LOCUS NC_013928:3 18207 bp DNA linear BCT 06-SEP-2013 DEFINITION Streptococcus mutans NN2025, complete genome. ACCESSION NC_013928 SOURCE Streptococcus mutans NN2025, complete genome. COMMENT locus start: 370893; locus end: 389099 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.979445; n0_4mer:D = 23.771503; n0_4mer:PS = 41.929831 FEATURES Location/Qualifiers source 1..18207 /organism="Streptococcus mutans NN2025, complete genome." gene 1..717 /gene="" /locus_tag="" /db_xref="370893..371609" CDS 1..717 /gene="" /product="hypothetical protein" /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKQGEPDPESN SALKFVLERAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN VNRTAANLRTAFGKNGGNMGAAGSVSYMFDKKGVIVFAGDDADSIFEQLLEADIDVED VEAEDGSVTVYTAPTDLHRGIEALRAGGVAEFQVTELEMIPQSEVTLEGEDLETFEKL IDALEDDDDVQKVYHNVDGL" gene 910..1257 /gene="" /locus_tag="" /db_xref="371802..372149" CDS 910..1257 /gene="" /product="bacterocin transport accessory protein" /translation="MSHFTEAIKHFNALTAQEAQEKIDSGEKFILFIGRSTCPYCQRF APKLSQVAADTGQTVAFLNSENQDDLTAVQAFREKYHVQTVPGLLVAQAGQVKVVCDS SLSQEAIADFIAQ" gene 1432..1815 /gene="yajC" /locus_tag="yajC" /db_xref="372324..372707" CDS 1432..1815 /gene="yajC" /product="hypothetical protein" /translation="MSYTTIIMFVVLIGAIFLMQRSQKKQAQERQNQLNAIAKGDEVV TIGGMYAVVDEVDNDNKKIVLDVDGVFLPFELTAIKRVVTKESQTVETDQTPEEATEI IETSKIEEKGSDSKETASTESAIEE" gene 1927..2676 /gene="uppS" /locus_tag="uppS" /db_xref="372819..373568" CDS 1927..2676 /gene="uppS" /product="UDP pyrophosphate synthetase" /translation="MFTLRRKKQDIKLSKIPAHIGIIMDGNGRWAKKRMKPRVFGHKA GMDALQDVTIAASELGVKILTVYAFSTENWARPQEEVKFIMNLPVEFFDKYVPKLHKN NVRILVIGDKEELPAATLDALERARELTKHNSGLILNFALNYGGRAEIVGAVKLIAQD VLDARFNPGDITEGLIADYLMTSNLPYLYRDPDLIIRTSGELRLSNFLPWQAAYSELY FTDTLWPDFDKKALYLAIEEFNHRHRRFGGV" gene 2691..3485 /gene="cdsA" /locus_tag="cdsA" /db_xref="373583..374377" CDS 2691..3485 /gene="cdsA" /product="phosphatidate cytidylyltransferase" /translation="MQKRVLFGGVALAIFLPFLFLGGLFFQLFVGVLAMIGVSELLKM KALEIFSFEGILAMLAAFVLTIPLENYLTFLPIDGSFSAFGLVIFLILAGTVLNTNRY SFEDAAFPIASSLYVGIGFQNLVNARISGLDKVFLALFIVWATDIGAYMIGRQFGQRK LMPAVSPNKTIEGSLGGILSAVVIAFIFMLFDKNVYAPHHFLVMLILVALFSIFAQFG DLVESSIKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHFFGLF" gene 3501..4760 /gene="" /locus_tag="" /db_xref="374393..375652" CDS 3501..4760 /gene="" /product="hypothetical protein" /translation="MSGLIAFIIIFGIIVLVHEFGHFYFARKSGILVREFTIGMGPKI FAHQGKDGTAYTIRILPLGGYVRMAGWGEDTSEIKTGIPVALTLNKAGVVTRIDLSDR QVDKTALPINVIAYDLEDKLEITGRVLEETKTYPVDHDATIVEEDGTEVRIAPLDVQY QKASIWGRLITNFAGPMNNFILGIFVFALLIFVQGGVQDSSSNHVRVTPNSAVAKLGL KNNDQILQIGKNKVHNWNDLTNAVAKSTSNLKKKEAIPVKAKTQGSVKTLKVIPKKVN GNYVIGVMPSMKTGFGDKIVGAFKMSWDGAFVILNGLKGLILQPSLNKLGGPVAIYQL SNTAAREGFARVLELMAMLSINLGIFNLLPIPALDGGKILINFIEVIRKKPLKQETET YITLAGVLIMVALMIAVTWNDIMRAFF" gene 4787..6637 /gene="proS" /locus_tag="proS" /db_xref="375679..377529" CDS 4787..6637 /gene="proS" /product="prolyl-tRNA synthetase" /translation="MKQSNMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYSYLP LAHRVIEKIKEIMREEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDQS DFILGPTHEETFTNLIRDAVKSYKQLPLNLYQIQAKYRDEKRPRNGLLRTREFIMKDG YSFHADYDSLDATYEDYRKAYEAIFTRVGLDFKAIIGDGGAMGGKDSQEFMAVTPDRT DLEHWLVLDKAIGSIEEIPADVLKEIKQELSSWLISGEDTIAYSSESDYAANLEMATS EYKPNNKVVSHEDIQRIETPNCKTIDEVAAFLEIDPTQTIKTLLFIADDEPVVALLVG NDQVNEVKLKNYLGADFLEPANEEEAREIFSASFGSLGPVNLPENVKIVADRKVKNIG NAVVGANEDGYHLTGVNPERDFEAAYVDIREVCEGEASPDGKGVLKFARGIEIGHIFK LGTRYSESMGSNILDENGRSIPIIMGSYGIGVSRILSAVIEQNARIFVNKTPKGAYRF SWGVNFPKTLAPFDVHLITVNVKDEVSQQLTAKVEESLVDAHYSVLTDNRNERIGSKF SDSDLIGLPIRVTVGKKASDGIVEVKIKSTGDTIEVNAENLLETLSILID" gene 6980..8530 /gene="" /locus_tag="" /db_xref="377872..379422" gene 8589..8660 /gene="" /locus_tag="" /db_xref="379481..379552" CDS 8589..8660 /gene="" /product="tRNA-Ala" /translation="GALAQLGERLLCTQEVSGSIPLG" gene 8920..11819 /gene="" /locus_tag="" /db_xref="379812..382711" gene 11884..12002 /gene="" /locus_tag="" /db_xref="382776..382894" gene 12004..12075 /gene="" /locus_tag="" /db_xref="382896..382967" CDS 12004..12075 /gene="" /product="tRNA-Val" /translation="GSLAQLGEHLPYKQRVSGSSPLT" gene 12106..12177 /gene="" /locus_tag="" /db_xref="382998..383069" gene 12206..12277 /gene="" /locus_tag="" /db_xref="383098..383169" CDS 12206..12277 /gene="" /product="tRNA-Lys" /translation="DSLAQLVEHLTFNQRVTGSSPVR" gene 12288..12368 /gene="" /locus_tag="" /db_xref="383180..383260" gene 12384..12455 /gene="" /locus_tag="" /db_xref="383276..383347" CDS 12384..12455 /gene="" /product="tRNA-Thr" /translation="AGLAQLVEHLICNQRVACSSHVA" gene 12459..12530 /gene="" /locus_tag="" /db_xref="383351..383422" gene complement(12766..13086) /gene="" /locus_tag="" /db_xref="383658..383978" CDS complement(12766..13086) /gene="" /product="hypothetical protein" /translation="MAFTNTKGRYASFGVVTSLPPELIDVFWEILDNNLKGVFTLDTL LTFQLVNNQGQLSFKYYDKYSKTVIVSDYATKFDPFYPEIVQIIDNNGRETIILPYEL DIDL" gene complement(13144..13677) /gene="" /locus_tag="" /db_xref="384036..384569" CDS complement(13144..13677) /gene="" /product="hypothetical protein" /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAVIGVNDH TLVTESDGRRWVTREPAIVYFHKKFWFNIIAMIRDNGVSYYCNLASPYIMDQEALKYI DYDLDVKVFADGEKKLLDVDEYELHKQKMGYSSDIDYILKENVKILVDWINNGKGPFS QSYINIWYKRYLELKNR" gene complement(13763..14539) /gene="recX" /locus_tag="recX" /db_xref="384655..385431" CDS complement(13763..14539) /gene="recX" /product="RecA regulator" /translation="MKITKIEKKKRLYLIEIDEAEHFYITEDTIVHFMLSKNKEILPE QLEEIKTFAQFSYGKNLALYYLSFKQRTEKEVKDYLIRHDINTTVIPQILTQLKEEKW LDDSKYIDNILQQNLHSGDKGAFILKQKLLQKGIESQLIEDMLKDFDFSSICIKTAQK LLKKYQSKLPKRALEDKLKQALTTKGFSYQEAQIALEDLDIENNSENEEELIYKELDK QYRKYSKKYENYELRQRLTQSLARKGFAFDAIKNALREYL" gene 14575..15954 /gene="" /locus_tag="" /db_xref="385467..386846" CDS 14575..15954 /gene="" /product="RNA methyltransferase" /translation="MNLRVKQKIPLKIKRMGINGEGIGFYKRTLVFVPGALKGEEIFC QITSVKHNFVQARLLTINKKSKFRVRPACPIYEECGGCQIMHLRYDKQLDFKKDLLKQ ALKKFKPQGYETYDVRATIGMEHPQHYRAKLQFQTRKFGGSVRVGLFKEQSHHLVDIK DCLIQDELTQKIVNRVCQLLDDYNIPVYDERRHFAGVRTIMVRKSQATNQVQLIFVTS KEVNLVGIIRDLTGYFPEIKTVAVNFNSSKSSAIYGQKTEILWGIDSISEEVLDYSFS LSPRAFYQLNPKQTQVLYHQALQALDVTAEDHLIDAYCGVGSIGLAFANKVKSVRGMD IIPEAITDAKRNAERMGYTNTYYEMGKAENIIPKWYKDGYQASALIVDPPRTGLDEKL LKTLLTYQPEKMVYISCNVSTLARDLVQLVKIYEVNYIQSVDMFPHTARTEAVVKLVK RKQNSCSKK" gene 15964..16425 /gene="nrdI" /locus_tag="nrdI" /db_xref="386856..387317" CDS 15964..16425 /gene="nrdI" /product="ribonucleotide reductase" /translation="MTKTITLIYISLSGNTKSFVARLTNYLQSKTDLTIHSVNVKDLV KDQADYFALSDYFVAFLPTYLEGGNGLDSGDIEILTTPLREFIAFADNYRYCYGIVGS GNKNFNNQYCLTAKQYAEQFGFPVLDNFELRGLADDVERIGDKILALYAAN" gene complement(16517..16586) /gene="" /locus_tag="" /db_xref="387409..387478" gene 16742..16996 /gene="" /locus_tag="" /db_xref="387634..387888" CDS 16742..16996 /gene="" /product="hypothetical protein" /translation="MSYEQEFLREFEAWVNSQVTINEMAMNASRKIIEEDKDERAADA YIRYESKLDAYKFIQGKFENYKAGKGFHDIPDGLFGERNY" gene 17179..17481 /gene="" /locus_tag="" /db_xref="388071..388373" CDS 17179..17481 /gene="" /product="sugar phosphate sensor protein" /translation="MTFVPVNWQGRFFVEGRSCLIEIYALVDNVKSLPHSLTPHVTLA YYHINGLPAEQAGKLKKTVAELNETPHDFILDNERLYCQTFTSMKDYRIVFPLIKE" gene 17485..18066 /gene="" /locus_tag="" /db_xref="388377..388958" CDS 17485..18066 /gene="" /product="cytosolic protein" /translation="MKIPFETEKLYYGFPIFLLGYRDETCGYNITTCSSSYSLGNMLV VGIGLKTNAAQKIKKFGRFTVNIPTEKSMQAIEQAGFVSHRDKFSLTGLDYSLSDIVD APILTDCPLVLECQVEKIIEKDNVAHIFAHIAGRKIDEKLIVKHQFRSQDFDPVYFMG DGKERIYRYLDQERSDKLGRFRRKSQEQNSEDL" ORIGIN 1 atgggacgta agtgggctaa tattgtcgct aaaaaaactg ctaaagacgg tgcaaactct 61 aaagtttatg ctaagtttgg tgtcgaaatc tatgtggctg ccaagcaagg ggagccagat 121 ccagaatcaa attcagcttt gaaatttgtt ttggaacgtg ctaaacaagc acaggttcca 181 aaacatgtta ttgataaggc tattgataag gctaaaggaa atacggatga aactttcgtg 241 gaaggtcgtt atgaaggctt tgggccaaac ggttccatga ttattgtgga taccttgact 301 tcaaatgtta accgtacagc agccaatctt cggactgctt ttggtaagaa tggcgggaat 361 atgggagcag ctggatctgt ttcttatatg tttgataaaa aaggtgttat tgtctttgca 421 ggtgacgatg cggacagtat ctttgaacaa ttgcttgagg ctgatattga tgttgaagat 481 gttgaagcgg aagacggttc tgtaacagtt tatactgctc caacagacct tcacagaggt 541 attgaagcgc ttcgtgctgg cggtgttgca gaatttcaag tgaccgaact tgaaatgatt 601 cctcagtctg aagtgacact tgaaggggaa gatttggaaa cctttgaaaa acttattgat 661 gctcttgaag acgatgacga tgtgcaaaaa gtttatcaca atgttgatgg cttataagca 721 aaaagaaacc ttgcaaattt tgtgaggttt ttttcttgcc ttcaaattaa agctggaaca 781 taggtcattt agtcgtataa agtgtagaag caatgctgtc agtggtctga aaatttacag 841 acaggctaat tgaaaattta aacaaaaaaa gctatgataa gactattaaa aaagaagtga 901 ggaaaattca tgtcacattt tacagaagcg attaaacatt ttaacgctct aacagcacaa 961 gaagcacagg aaaagattga tagtggagaa aagtttattc ttttcattgg acgttcaact 1021 tgtccttact gtcagcgttt tgctcctaag ttgagtcagg ttgctgcaga tacaggtcag 1081 acagtcgctt ttttaaatag tgaaaatcaa gatgatttaa cagctgttca agctttccgt 1141 gagaaatacc atgttcagac agtaccgggg cttttagttg ctcaagcagg acaagtcaaa 1201 gttgtttgtg attcatcgct ttcacaagag gctattgctg attttattgc tcaatagtta 1261 aggtttagac tgtttggcta ttttggtctc ttaatgttat cgtcctttta aatttttgag 1321 tttttataag gcttcgtttt aggcagaaat tgattttgca cttgctctta gcatctaatt 1381 ttgttatagt atgtgatggc tttattatta aagagatgag gagaatatac tatgtcttat 1441 actacaatta tcatgtttgt tgttttgatt ggagccatct ttttgatgca gcgttcccaa 1501 aagaaacaag ctcaagagcg gcaaaatcaa ttaaatgcta ttgctaaagg agatgaagtt 1561 gtcaccattg gcggtatgta cgctgttgtt gatgaagtgg acaatgataa taaaaagatt 1621 gttcttgacg ttgacggtgt cttcttgcct tttgaactaa cggcaattaa gcgcgttgta 1681 acaaaagaaa gtcagactgt agaaactgat caaacgccgg aagaagcaac tgaaattatt 1741 gaaacttcaa aaatagaaga aaaaggttca gattctaagg aaacagcaag tactgaatct 1801 gccattgaag aataattata aacctcaatc gttgtgattg gggctttttt caactggaat 1861 aaaattcgtt cataaatctt aaattatggt aaaatagatc tgatagtatt ttttaaggaa 1921 aaaataatgt ttacattaag acgaaaaaaa caagatataa aattatctaa aatcccagct 1981 catatcggta tcattatgga tggcaatgga cgctgggcta agaaacgaat gaaaccaagg 2041 gtatttggac ataaggctgg tatggatgcc cttcaagatg tgacgatagc ggcatcggaa 2101 cttggagtca aaattttaac agtttatgct ttttcaacgg aaaattgggc tcgtcctcaa 2161 gaagaggtta aatttatcat gaatttacct gtagagttct ttgataagta tgttcctaag 2221 ctgcataaaa ataatgttcg tattttagtg attggcgata aggaagaact gccggcagca 2281 actttagatg ctctggaacg cgctagagaa ctgactaaac ataattctgg acttatttta 2341 aattttgctt tgaattatgg cggtcgtgct gaaattgttg gtgctgtaaa gttgattgct 2401 caagatgttt tagatgctcg gtttaaccct ggtgatatta cagaagggct cattgctgat 2461 tacttgatga caagcaatct tccttacctt taccgtgatc ccgatttgat tattagaacg 2521 agtggtgagc tgcgtcttag taacttttta ccgtggcagg ctgcttatag tgagctttat 2581 tttacagata cactttggcc agattttgat aaaaaagctt tgtatttagc tattgaagaa 2641 tttaaccatc gccatcgtcg ctttggtggt gtttagaaag aggatttatc atgcagaaac 2701 gtgttctttt tgggggagtg gctctggcta tttttctccc tttcctattt ttgggaggtc 2761 tcttttttca gctttttgtt ggtgttctag ccatgattgg cgtatctgaa ctgttgaaaa 2821 tgaaggcgtt agaaattttt tcatttgaag gtattttagc tatgcttgcg gcttttgtgc 2881 tgactattcc tttagagaac tacctgactt ttttaccgat tgatggcagc tttagtgctt 2941 ttggtctcgt tatctttttg attttagcag gaacggtctt aaatactaat cgctattctt 3001 tcgaagatgc tgcttttcct attgcttcca gtctttacgt tgggattggt tttcaaaatc 3061 tcgttaatgc tcgcatttct ggacttgata aagtttttct agcccttttt atcgtttggg 3121 cgactgatat tggagcttat atgattggtc ggcagtttgg tcaacgtaaa ttgatgccgg 3181 cagtttctcc taacaagact attgaaggca gcttaggagg aattttgtcg gcagttgtca 3241 ttgcttttat ctttatgttg tttgataaga atgtttacgc accgcatcac ttcttagtca 3301 tgcttatttt ggttgctctc tttagtatct ttgcccaatt tggtgatcta gttgaaagtt 3361 caattaaacg acattttggt gttaaggatt ctggcaaact cataccaggg cacggaggta 3421 ttttagaccg ttttgacagt atgatttttg tttttccaat catgcacttc tttggtttgt 3481 tctaaaagga ggaggaaaga atgtcaggac taatagcttt tattattatc tttggaatta 3541 tagttcttgt ccatgaattt ggtcatttct attttgctag aaaatcagga attttggttc 3601 gggaatttac cattggtatg gggccgaaaa tttttgcaca tcaaggaaaa gacggtacag 3661 cttataccat tcgaattctg cctttaggtg gctatgtccg tatggctggc tggggagaag 3721 atactagcga aattaaaaca gggatacctg tcgctttgac gcttaataaa gcaggtgtgg 3781 tcactcgtat tgacctttct gacaggcagg tagacaagac ggccttgcct ataaatgtga 3841 tagcttatga tttagaagac aaattagaga ttacaggacg cgttcttgaa gaaactaaga 3901 cttatccagt ggatcatgat gcaacaattg ttgaagagga tggaacagaa gttcgcattg 3961 caccgctgga tgtgcaatat caaaaggcta gtatttgggg acgtttaatc actaattttg 4021 cgggtcccat gaataacttt atcttaggta tttttgtttt tgccctcttg atttttgtgc 4081 aaggcggtgt tcaggattct tcaagcaatc atgtgcgtgt gactcctaac agtgctgtag 4141 ctaagctcgg acttaagaat aatgatcaaa ttttacaaat cgggaaaaac aaagttcata 4201 attggaatga tctaactaat gcggttgcta agtcaactag taatttgaaa aagaaagaag 4261 ctattccagt taaggctaag actcaaggaa gcgtaaaaac tttaaaagtt atccctaaaa 4321 aagttaatgg gaattacgtt attggtgtca tgccaagtat gaaaacagga tttggggata 4381 aaattgttgg tgcctttaag atgtcttggg acggcgcttt tgttatcttg aatggtctta 4441 aagggctgat cctacagcca agtctcaata aattaggtgg tcctgttgcg atttatcaac 4501 tgagtaatac agctgctaga gaaggttttg caagagtcct tgaattaatg gctatgcttt 4561 ctattaatct gggtattttt aatttgttgc ctattcctgc tcttgatggt ggtaaaattt 4621 taatcaattt tatagaagtt attcgaaaaa aaccgctcaa acaagagaca gaaacctata 4681 ttaccctcgc tggtgttctt attatggttg cgcttatgat tgcagtaact tggaatgata 4741 tcatgcgagc atttttctaa attaatgaga cggagtataa tttttaatga aacaaagtaa 4801 tatgttaatc ccaaccttgc gcgaaatgcc aagtgatgca caagtcatca gtcatgccct 4861 tatggtgcgt gctggttatg tccgccaagt atcggcaggg atttactctt atttaccttt 4921 agctcatcgc gttattgaaa aaattaaaga aatcatgcgt gaagaatttg ataaaattgg 4981 tgctgttgaa atgctggcac ctgccctttt aacagctgac ttatggcgtg aatccggccg 5041 atatgaaact tatggggaag atctttataa gttaaaaaat cgcgatcaat cagattttat 5101 tttagggccg actcatgaag aaacttttac aaatctcatc cgtgatgcag tgaaatctta 5161 caagcagctt cccttgaatc tttatcaaat tcaagcaaaa tatcgtgacg aaaaacgccc 5221 tcgcaatggc ttacttcgta ctcgtgaatt tatcatgaaa gatggctata gttttcatgc 5281 tgattatgac agtttagatg ctacttatga agattatcgt aaggcttatg aagctatttt 5341 tactagagtt ggtttagatt ttaaagcgat tattggtgat ggcggtgcta tgggtggtaa 5401 agatagtcag gaatttatgg cagtaacgcc agatcgtaca gatttggagc attggctggt 5461 tcttgataaa gctattggct ctattgaaga gattccagct gatgttttga aagagattaa 5521 acaagaactc tcctcttggt taatatcagg agaggatact atcgcttatt caagcgagtc 5581 tgattatgcg gctaatctgg aaatggcgac gagcgaatat aagcctaaca ataaggttgt 5641 ttctcatgaa gatatacagc gtattgaaac accaaattgt aaaacgattg atgaagttgc 5701 tgccttttta gaaatagatc caacacaaac cataaaaacc ttgttattta ttgcagatga 5761 tgaaccagtt gttgctttac ttgtaggaaa tgatcaggtt aatgaagtta aactaaaaaa 5821 ctatctgggt gctgacttct tggaaccagc taatgaagaa gaagcaagag aaatttttag 5881 tgcttccttt ggttctctag gtccagttaa tctaccagaa aatgtcaaaa ttgtggcaga 5941 tcgtaaggtg aaaaatattg ggaatgccgt tgttggtgct aatgaagatg gttatcattt 6001 gacaggtgtc aatccggaac gtgactttga agctgcttat gttgatattc gtgaagtctg 6061 tgaaggagag gcatctccag atggtaaagg tgttcttaaa tttgcgcgtg gtattgaaat 6121 tggtcacatt tttaaattgg gaacacgtta ttcagaaagt atgggatcta acattcttga 6181 tgaaaatgga cgttcaatcc ctattattat gggaagttat ggcatcggtg ttagtagaat 6241 tctatcagca gtcattgaac aaaatgcacg tatctttgtt aataagacac ctaaaggagc 6301 ttaccgattt tcttggggag ttaattttcc taaaacgttg gcgccatttg acgtccatct 6361 cattacggtt aatgtaaagg atgaagtctc ccaacaattg acagcaaaag tagaagaaag 6421 tttggtagat gctcactatt ctgttttaac agataatcgg aatgagcgta ttggttcgaa 6481 attttctgat agtgacctta ttgggctgcc gattcgtgta acagttggta aaaaagcttc 6541 agatggtatt gtagaagtta aaataaaatc gactggagat acaattgaag tcaatgcgga 6601 gaacctatta gaaactttat ctattttgat agactagaat ttttttgaag gctgagctac 6661 ttgtgcccag ccttttgata tttaagatat tataaaatca ggttcagaaa gagaatgagc 6721 gattcagcag ttgattttta ataatcaata gtgtatttgt caaaactttt tgaaattctt 6781 ttgaaaaagt cttgacaaaa ttataaatac tttgatatac tatgaaagtt gctgtttaaa 6841 gtagcactaa gctctttgaa aactgaacaa gaagacgaac caaccaaagt gcagggtgac 6901 ataaagaaat gtgacctgtc aaagaacgaa aaaaaaactg tcagagtgca gaaatgagtg 6961 aagactcaag cttttaatga gagtttgatc ctggctcagg acgaacgctg gcggcgtgcc 7021 taatacatgc aagtgggacg caagagaaca cactgtgctt gcacaccgtg ttttcttgag 7081 tcgcgaacgg gtgagtaacg cgtaggtaac ctgcctatta gcgggggata actattggaa 7141 acgatagcta ataccgcata atattaatta ttgcatgata attgattgaa agatgcaagc 7201 gcatcactag tagatggacc tgcgttgtat tagctagttg gtaaggtaag agcttaccaa 7261 ggcgacgata catagccgac ctgagagggt gatcggccac actgggactg agacacggcc 7321 cagactccta cgggaggcag cagtagggaa tcttcggcaa tggacgaaag tctgaccgag 7381 caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc tctgttgtaa gtcaagaacg 7441 tgtgtgagag tggaaagttc acacagtgac ggtagcttac cagaaaggga cggctaacta 7501 cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg tccggattta ttgggcgtaa 7561 agggagcgca ggcggtcagg aaagtctgga gtaaaaggct atggctcaac catagtgtgc 7621 tctggaaact gtctgacttg agtgcagaag gggagagtgg aattccatgt gtagcggtga 7681 aatgcgtaga tatatggagg aacaccagtg gcgaaagcgg ctctctggtc tgtcactgac 7741 gctgaggctc gaaagcgtgg gtagcgaaca ggattagata ccctggtagt ccacgccgta 7801 aacgatgagt gctaggtgtt aggccctttc cggggcttag tgccggagct aacgcaataa 7861 gcactccgcc tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg 7921 cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg aagaacctta ccaggtcttg 7981 acatcccgat gctattctta gagataggaa gttacttcgg tacatcggag acaggtggtg 8041 catggttgtc gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc 8101 cttattgtta gttgccatca ttaagttggg cactctagcg agactgccgg taataaaccg 8161 gaggaaggtg gggatgacgt caaatcatca tgccccttat gacctgggct acacacgtgc 8221 tacaatggtc ggtacaacga gttgcgagcc ggtgacggca agctaatctc tgaaagccga 8281 tctcagttcg gattggaggc tgcaactcgc ctccatgaag tcggaatcgc tagtaatcgc 8341 ggatcagcac gccgcggtga atacgttccc gggccttgta cacaccgccc gtcacaccac 8401 gagagtttgt aacacccgaa gtcggtgagg taacctttta ggggccagcc gcctaaggtg 8461 ggatggatga ttggggtgaa gtcgtaacaa ggtagccgta tcggaaggtg cggctggatc 8521 acctcctttc taaggaaaaa cgcaaagcac attaggggaa cttcttgttt agttttgaga 8581 gggtaagtgg ggccttagct cagctgggag agcgcctgct ttgcacgcag gaggtcagcg 8641 gttcgatccc gctaggctcc attaaaacag gatactaaca gacggttcgc ttgcgaatac 8701 ttctgtagaa aattatctat ttttctaaga agtcagtctg gagttcaact tcatatcttg 8761 tttaagacaa ggaagtctat aaaatccact taggatatga taagtatcct agagatggtt 8821 cattgacaat tgaatagcta gtaaaagccc tatagcgcag ctatagggaa acaagaaaga 8881 aaccgagacg ctgaaaagcc agagaaacga gaaataaggt taagttaata agggcgcacg 8941 gtggatgcct aggcactagg agccgatgaa ggacgtgacg aacgacgaca tgctttgggg 9001 agctgtaagt aagccttgat ccagagatat ccgaatgggg gaacccaaca ggtaatgcct 9061 gttatccata actgttaagg ttatgagaag gaagacgcag tgaactgaaa catctcagta 9121 gctgcaggaa gagaaagcaa gagcgattgc ctcagtagcg gcgagcgaag aggcaggagg 9181 gcaaaccaga gtgtttacac tctggggttg taggactgcg ataaagcagc caagggaata 9241 gaagaagact ctgggaagag tcgccagaga gagtaagagc ctcgtatttg aaattcactt 9301 gatgccaagc aggatcctga gtacggcggg acacgaggaa tcccgtcgga atctgggagg 9361 cccatctccc aaccctaaat actccctagt gaccgatagt gaaccagtac cgtgagggaa 9421 aggtgaaaag taccccggaa ggggagtgaa agagaacctg aaaccgtgtg cttacaagaa 9481 gttcgagccc gttaatgggt gagagcgtgc cttttgtaga atgaaccggc gagttacgtt 9541 tacgtgcgag gttaagttga agagacggag ccgtagggaa accgagtctg aaaagggcgg 9601 ttaagtacgt agatgtagac ccgaaaccaa gtgacctacc catgagcagg ttgaaggtgc 9661 ggtaaaacgc actggaggac cgaaccagga cacgttgaaa agtgtttgga tgacttgtgg 9721 gtagcggaga aattccaaac gaacttggag atagctggtt ctctccgaaa tagctttagg 9781 gctagcgtcg gtcgcgagac tcttggaggt agagcactgt ttgattgagg ggtccatccc 9841 ggattaccaa tctcagataa actccgaatg ccaacgagtt aagaccggca gtcagactgc 9901 gagtgctaag atccgtagtc gaaagggaaa cagcccagac caccagctaa ggtccctaaa 9961 taattgttaa gtggaaaagg atgtggggtt gcacagacaa ctaggatgtt agcttagaag 10021 cagctattca ttcaaagagt gcgtaatagc tcactagtcg agtgaccctg cgccgaaaat 10081 gtaccggggc tgaaacaatt taccgaagct gtggatccct taggggatgg taggagagcg 10141 ttctatgtgc gcagaaggtg taccgcaagg agcgctggag tgcatagaag tgagaatgcc 10201 ggtatgagta gcgtaagaca ggtgagaatc ctgtccaccg taagactaag gattccaggg 10261 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgatagg tgtatccgat 10321 gggcaacagg ttgatattcc tgtactagag tattgagtga aggagggacg cagcaggcta 10381 actagagcgt gcgattggaa gagcacgtcc aagcagtgag gtgaggactg agtcaaatgc 10441 ttagttctgc gccaccaagc tgtgacgggg agcgaagttt agtagcgaag ctagtgatgt 10501 cactctgcca agaaaagctt ctagcgttaa tgaatactct acccgtaccg caaaccgaca 10561 caggtagtcg aggcgagtag cctcaggtga gcgagcgaac tctcgttaag gaactcggca 10621 aaatggcccc gtaacttcgg gagaaggggc gctggcgata agtcagccgc agtgaaaagg 10681 cccaagcaac tgtttatcaa aaacacagct ctctgcgaaa tcgtaagatg aagtataggg 10741 ggtgacgcct gcccggtgct ggaaggttaa gaggagcgct tagacgtttg tcgaaggtgt 10801 gaattgaagc cccagtaaac ggcggccgta actataacgg tcctaaggta gcgaaattcc 10861 ttgtcgggta agttccgacc cgcacgaaag gcgtaatgat ttgggcactg tctcaacgag 10921 agactcggtg aaattttagt acctgtgaag atgcaggtta cccgcgacag gacggaaaga 10981 ccccatggag ctttactgca gtttgatatt gcgtatctgt tacacatgta caggataggt 11041 aggagccaag gaagagtgaa cgctagttta cttggaggcg atgttgggat actacccttg 11101 tgtgatggct actctaaccc ggtaggttga tcatctacgg agacagtgtc tgacgggcag 11161 tttgactggg gcggtcgcct cctaaagtgt aacggaggcg cccaaaggtt ccctcagact 11221 ggttggaaat cagtcgcaga gtgtaaaggt ataagggagc ttgactgcga gacagacaag 11281 tcgagcaggg acgaaagtcg ggcttagtga tccggtggta ccgtatggaa gggccatcgc 11341 tcaacggata aaagctaccc tggggataac aggcttatct cccccaagag ttcacatcga 11401 cggggaggtt tggcacctcg atgtcggctc gtcgcatcct ggggctgtag tcggtcccaa 11461 gggttgggct gttcgcccat taaagcggca cgcgagctgg gttcagaacg tcgtgagaca 11521 gttcggtccc tatccgtcgc gggcgaagga aatttgagag gatctgctcc tagtacgaga 11581 ggaccagagt ggacttaccg ctggtgtacc agttgttctg ccaagagcat cgctgggtag 11641 ctaagtaggg aggggataaa cgctgaaagc atctaagtgt gaagcccccc tcaagatgag 11701 atttcccata acgttcagtt agtaagagcc ctgagagaag aacaggtaga taggttggga 11761 gtggaagcgt tgtgagacgt gaagcggacc aatactaatc gctcgaggac ttatccaaaa 11821 aaagcaggcg cagcgtcggt ttcagtggct agctattcaa tcgtgagtga gcgatcacgc 11881 ttgttaagtg atgatagcct aggggagaca cctgtaccca tgccgaacac agcagttaag 11941 ccctagcacg cctgaagtag ttgggggttg ccccctgtga gatagggtcg tcgcttagca 12001 agagggagtt tagctcagtt gggagagcat ctgccttaca agcagagggt cagcggttcg 12061 agcccgttaa ctcccataac taagtaacta aagtgattag ttagaggtcc cgtggtgtag 12121 cggttatcac gtcgccctgt cacggcgaag atcgcgggtt cgattcccgt cgggaccgtc 12181 tttttctgaa aagagaggga tcatcgactc gttagctcag ttggtagagc atttgacttt 12241 taatcaaagg gtcactggtt cgagcccagt acgggtcatc aagagatgcg ggtgtggcgg 12301 aattggcaga cgcaccagat ttaggatctg gcgcttaagg gcgtgggggt tcaagtccct 12361 tcacccgcat atagaggaga taggccggct tagctcagtt ggtagagcat ctgatttgta 12421 atcagagggt cgcgtgttca agtcatgtag ccggcattgc gaacgtagtt cagtggtaga 12481 acatcacctt gccaaggtgg gggtcgcggg ttcgaatcct atacgtaggt tgacttataa 12541 catatccaga gagaaggcta cccttgacct tctcttttat ggctccttgt caactgtaat 12601 aagtgattga taaagcgtgc gagagaatca gattggttct ctcttttgtg atgttcaaat 12661 ttttagtagc taatataact aaaaacactc ctaagttgga cttttgtatc caattttaga 12721 agtgcttaca agtgaattgc ttttaaatta ccattatttg aaaagttaca aatctatgtc 12781 caattcataa gggagaataa tagtttctct gccattatta tcaataattt gtacgatttc 12841 tggatagaaa gggtcaaatt tggttgcata gtcagataca ataacggttt tactgtattt 12901 atcgtagtac ttaaaactca gttgcccttg attattcact aattgaaagg ttaaaagagt 12961 atcaagtgta aaaacgcctt ttaagttatt atcaagaatt tcccaaaaaa catcaatcaa 13021 ttcgggaggt aaacttgtta ccacaccaaa acttgcatac cgtccctttg tatttgtaaa 13081 ggccatgata taagactcct ttctataaaa aagaaagcac cactgaagtg ctttttgaca 13141 actttaacga ttcttaagtt caagataacg tttgtaccaa atattgatat aggattgtga 13201 aaagggtcct ttaccattat taatccagtc tactaaaatt ttgacatttt ctttcaaaat 13261 gtagtcgata tcagaagaat atcccatttt ttgtttatgt aactcatatt catcaacatc 13321 tagaagtttt ttttcaccat ctgcaaaaac cttaacatct aaatcataat cgatatactt 13381 taatgcttct tgatccatta tataaggact agctaagttg caatagtaag aaacgccatt 13441 atctcgaatc attgcgatga tattaaacca gaatttttta tgaaagtaaa caatagctgg 13501 ttcgcgggtt acccatcgtc tcccatcact ttcagtgact agcgtatgat cattaacacc 13561 aataacggca ttttctgttg tttttagtac catagtgtcg cgccaagttc ggtgcaaact 13621 accatcatgc ttataacttt gaattgtaat aaagtcgcct tccttaggta atttcattgc 13681 cttaccaact ttctacaatt aagcttgtcc tttacagttt aacataattt caagaaaaaa 13741 gcattttttt ctgtcagaaa ggttacaaat actcccgtaa ggcattttta atagcatcaa 13801 aggcaaagcc ttttctggct aagctttgtg tcaggcgttg tctgagttca taattttcat 13861 attttttact atatttccga tattgtttat ctagttcttt ataaataagt tcttcttcat 13921 tttcagaatt gttttcaata tctaaatctt caagagctat ttgggcttct tgataggaaa 13981 atcctttggt cgttaaggct tgcttgagtt tatcctcgag agctcttttt gggagcttac 14041 tttgatattt tttaaggagt ttttgggccg ttttaatgca aatactgctg aaatcaaaat 14101 cttttaacat gtcttcaatt aattgagatt cgattccttt ttgaagtaat ttctgtttaa 14161 ggataaaggc gcctttatca ccagaatgaa gattttgctg caatatattg tcgatatatt 14221 tactgtcatc aagccacttt tcctctttta attgggtgag aatctgagga ataacagtag 14281 tgttaatatc atgtcttatc agataatctt tgacttcttt ttccgtgcgc tgtttaaaag 14341 aaagataata cagagcaagg tttttaccat aagaaaattg ggcaaaggtc ttgatttctt 14401 ctagttgctc aggaagaatt tctttattct tgctgagcat aaaatggaca atggtatctt 14461 cagtgatata gaaatgttca gcttcatcaa tttcaatcag ataaagtctt tttttctttt 14521 caattttagt aattttcatg cctttattat agcagaaaat gatagaatag tagtatgaat 14581 ttacgagtaa aacaaaagat tcccttgaaa atcaagagaa tgggaattaa cggtgaagga 14641 attggctttt ataagagaac cttagttttt gttcccggtg ctctgaaagg tgaagagatt 14701 ttttgtcaaa taaccagtgt taaacacaat ttcgtgcaag ccagactatt gaccatcaat 14761 aaaaaatcta aatttcgggt gcggcctgct tgtcctattt atgaggaatg tggcggctgt 14821 caaatcatgc atttacgtta tgataaacaa ttggatttca aaaaagattt gctaaagcaa 14881 gctttgaaaa aatttaagcc gcaaggttat gagacctatg acgttcgagc gacaattgga 14941 atggaacacc ctcagcatta tcgcgccaag ttacaatttc agacgagaaa atttggcggt 15001 tctgttagag tgggactttt caaagagcag agtcatcatt tggtagatat taaagattgc 15061 ttgatacaag atgagctgac ccaaaaaatc gtcaatcgag tctgtcagct tttggacgac 15121 tacaatatcc ctgtttatga cgaacggcgt cattttgctg gtgtcagaac tatcatggtc 15181 agaaagtcac aagctaccaa tcaagttcag ttgatttttg taaccagtaa ggaagttaat 15241 ctcgtcggaa ttattcgtga tttgacagga tattttccag aaattaagac ggttgccgtt 15301 aattttaatt ccagcaaatc cagtgctatt tatggtcaga aaacagaaat tctctggggt 15361 attgatagca tatcagagga agttttagat tattcctttt ctttatctcc cagagccttt 15421 tatcaactta atcccaaaca gacgcaggtt ctttatcatc aagcacttca agctcttgat 15481 gtgactgcag aagatcattt aattgatgct tactgtggtg tcggtagtat tggtcttgct 15541 tttgctaata aagtgaaatc agttagaggg atggatatca ttcctgaagc tattacagat 15601 gctaaaagaa atgctgagcg tatgggatac acaaacacct attatgaaat ggggaaagcc 15661 gaaaatatta ttccaaaatg gtacaaagac ggctatcaag catcggcgct tattgttgat 15721 ccacctagaa caggacttga tgagaaactt ttaaaaactc tgctaaccta tcagccagaa 15781 aaaatggttt atatctcttg taatgtttca actcttgcca gagatttggt tcaattggtt 15841 aaaatctatg aagtcaatta tatccaatcg gtcgatatgt ttcctcatac agcaagaact 15901 gaggctgttg ttaaattagt aaaacgaaaa caaaatagtt gttctaaaaa gtaaggaagt 15961 aaaatgacaa aaacaatcac tttaatttat attagtttaa gcggcaatac caaaagtttt 16021 gtagctcgct tgacaaacta tctacagtca aaaacggact taacaattca ttctgtcaat 16081 gtcaaagatt tagttaaaga tcaggcagat tattttgccc tatctgatta ttttgttgct 16141 ttcttaccaa cctatcttga aggtggaaat ggtcttgaca gtggggatat tgaaattttg 16201 acaacccctt tacgagagtt catagctttt gcagataatt atcgttattg ctatggcatt 16261 gttggttcag gcaataaaaa ttttaacaat caatattgtc tgacggctaa gcagtatgct 16321 gaacaattcg gttttcctgt gcttgataat tttgaattgc gcggtctagc cgatgatgtt 16381 gaacgtattg gtgataagat tttagcctta tacgcagcta actaatatct ttatttaaga 16441 acaaatagat caaacaagca acaatagaaa aaaggaactg agataatttt tcagatcctt 16501 tttcaattag tattattgcc accaccgaga atcgaactcg gaacggagca ttaccattgc 16561 tctattatac catttaacta tagcggcgac tcatctatca tactataaaa taatgaagaa 16621 tgcaaggagg gaaacttaat atcatttgtt cattaattta aattagaaaa cgaaatggct 16681 atctcttttt ctcttaaaat ggtataataa cagttacaga attttttaca aggaagatat 16741 gatgtcatac gaacaggaat ttttacgaga atttgaagct tgggtcaatt cacaagtgac 16801 cattaacgaa atggccatga atgctagtcg taaaatcatt gaagaagata aagatgagcg 16861 tgcagcagat gcttatattc gttatgagag caagctggat gcttataaat ttatccaagg 16921 aaaatttgaa aattataagg ctggcaaagg atttcacgat ataccagacg gtctttttgg 16981 tgagagaaat tattgatttc taaaggttaa tctgataaaa taaggtcatt cagaggtgtt 17041 ttgaattcca tttgttatag gaagcggcgt tactgggaaa tccgcacaaa tgtcgaaact 17101 ggttgctgat gtgatttttt gaaataaaat gagttgcggg tctagcccga aactgggtgg 17161 taccgcggag atcatagaat gacattcgtc cctgtcaatt ggcagggacg tttttttgtt 17221 gaagggaggt cttgcttgat agaaatttac gcattggtcg acaatgtcaa aagtttgccc 17281 cattctttga cgccgcatgt cactctagct tattatcata tcaatggttt gccagccgag 17341 caggcgggga aactgaaaaa gacggttgca gagctaaacg aaacgccgca tgattttatt 17401 ttggataatg agagacttta ctgtcaaacc tttaccagca tgaaagatta tcgaatcgtt 17461 tttcctctta taaaggagta gaatatgaaa ataccttttg aaactgagaa actttattat 17521 ggctttccta tctttctttt gggctataga gatgaaacct gcggttacaa tatcacaact 17581 tgctcttcct cttatagcct aggaaatatg cttgtcgtgg gaattggctt gaaaaccaat 17641 gccgcccaaa aaattaagaa atttggtcgt ttcacagtca atattcctac agaaaaatca 17701 atgcaagcta ttgagcaagc aggttttgtc agccatcgtg acaagttctc cctaactgga 17761 cttgattata gtctctctga tattgttgat gcccctatct taacagattg ccctcttgtt 17821 ttagaatgtc aagtcgaaaa aatcattgaa aaagataatg ttgcccatat ttttgctcat 17881 attgctggtc gtaagattga tgaaaaatta attgtgaaac atcagttcag gagtcaagat 17941 tttgatcccg tttatttcat gggcgatggt aaggagcgaa tttaccgtta cttggaccaa 18001 gaacggagcg ataagttagg acgttttaga cgaaagtcac aagaacaaaa ttcagaggat 18061 ctgtaatgaa aattctagaa acttataatg gcaaagagta tacaatgaat acagatgtat 18121 ttcaaaagtg tgcatcttac aaaatatgaa gacggtagaa taaattagca tgagtttaaa 18181 agagaagact gtgtaatcat aaaattc //