LOCUS NC_013894:3 18477 bp DNA linear BCT 09-OCT-2011 DEFINITION Thermocrinis albus DSM 14484 chromosome, complete genome. ACCESSION NC_013894 SOURCE Thermocrinis albus DSM 14484 chromosome, complete genome. COMMENT locus start: 415776; locus end: 434252 FEATURES Location/Qualifiers source 1..18477 /organism="Thermocrinis albus DSM 14484 chromosome, complete genome." gene 0..1448 /gene="" /locus_tag="" /db_xref="415776..417224" CDS 0..1448 /gene="" /product="nitrogenase molybdenum-iron protein alpha chain" /translation="MGVLVDKETALKIIEEVLSAYPKKAKKDREKHIAVVEPQDDKCT PKSNIKSRPGVMTVRGCAYAGSKGVVWGPIKDMIHISHGPVGCGYYSRAGRRNYYIGT TGVDTFVTPHFTTDFQERDIVFGGDKKLMKAIEELNTLFPLAKGITIQSECPIGLIGD DIEAVARMASKKIGKPVIPVRCEGFRGVSQSLGHHIANDSMRDWIYEKGLKGQEIEST PYDVAIWGDYNIGGDAWATRKILEDMGLRVITQFSGDGTFSEVANAVKARYILVHCYR SSNYLARYFEEKFGIPWIEYNFFGPTQIFASMRKIAALFDDKIVERTEELIEKVYKPR LDRVIEKYRPRLEGKTVLLYVGGLRPRHMITAFEDLGMNVIATGYEFAHQDDYQRTLH YIDKNTTIIIDDATAYEIEELTRKLNPDLVASGIKEKYQAQKMGKPFRQMHSWDYSGP YHGIEGFEIFARDIDMAVNGNVWKYIEAPWKK" gene 1467..3105 /gene="" /locus_tag="" /db_xref="417243..418881" gene 3111..3680 /gene="" /locus_tag="" /db_xref="418887..419456" CDS 3111..3680 /gene="" /product="putative transcriptional regulator, Crp/Fnr family" /translation="MSVVERLKRYIEEGLVAEHTYKVGEDLSFEKGVYVVKEGVIELF TFKRKGKQVLDLLFKGDVIGFLLRNTSLTNYKARPLTPSTLFYIKEDALIKIGEKEPH LALDIFASLLSKQAYLYNVLTIVFAGDATEKIRDLMCLLERRAEEKGTYLTLRKSQIA SITGLSYEHVVRKMKCIRIKNKNGRIRLW" gene 3674..4135 /gene="" /locus_tag="" /db_xref="419450..419911" CDS 3674..4135 /gene="" /product="hypothetical protein" /translation="MVIKKEDIDLGEEVLKEIVRQVRAYDTYGTWEKRKDEDILKEFL KTSSKQIAHAGGSCSLDPRAMLKLHAYFKALGVIIERLSGYLTSAVINIDHEGNGTVI LYAGRLILINKSIRDANNFGFKSTDNIKQEAEKLINKALQLIEKYEEVCKI" gene 4132..5208 /gene="" /locus_tag="" /db_xref="419908..420984" CDS 4132..5208 /gene="" /product="DegT/DnrJ/EryC1/StrS aminotransferase" /translation="MRRLIPFKPYGYSKEDMISAVEAMGHPYCFSGLRRKELEDSFCQ YSGRKYAVATRDVVPGLLALLEYLGLSYGDTVAYTPLSLAPHFAKYTKFMGLNSAYAD VERWFFNVDVKRLSNVITSYKPKVLIVNNSLGIPADWDAVRELLKGTGIFLIEDSRET LFSDYKGRPAGSLGDVSFLAFSPNSVLRGYGGVILTDDALIYKRIREKVEPMDDIMAS LLISQTKSLEERINIRRELAQLYSQLLSNMEGMKPQFFPKYVNKPCWSYMCVHLAKRY GRDAVDSIVELMWDDGIETLKYPVSQDIQEGKSMPHLHISHEVSTRAILLPLHEDMDE EDVYFVCERFKDYVIQIGAGSVDH" gene 5223..6581 /gene="" /locus_tag="" /db_xref="420999..422357" CDS 5223..6581 /gene="" /product="nitrogenase MoFe cofactor biosynthesis protein NifE" /translation="MRNLEEFFTEPACGINKSKGDKEKKVGCSKPKPGSASGGCAFDG AQITLLPIADAVHIVHGPIACAGNSWDNRGTRSSSPITYYRMGFTTDLSEIDVIHGGE NKLYMAIKEAVEKYNPPAVFVYQTCVPAMIGDDIQAICNKASKDFNIPVVPVDSPGFV GSKNLGNKLAGDALFRYVIGTKEPEYTTPYDVNLLGEYNIAGELWQVLPLLQEAGFRI LACITGDSRYNDIATAHRAKVNMVVCSKALLNLARRMEEKYGIPYFEGSFYGIKDTSD ALRNMALLIGDKDLIERVEKLIEVKEAETKEKLKPYIEKLKGKKVLINTGGVKSWSMV AQVQELGMEVVGTSAKKSTEGDKGRMLELLGDEKKLIDDPNPKELIKIMRSENVDLLL AGGRSKFVAFKEGIPFLDVNQERIRGYAGYEGMLLLAEDIVRTLENPVWNLRRRKAPW QE" gene 6569..7912 /gene="" /locus_tag="" /db_xref="422345..423688" CDS 6569..7912 /gene="" /product="nitrogenase molybdenum-iron cofactor biosynthesis protein NifN" /translation="MARVVESKKALSVYPLKLSQPLGAMYAFMGVKGSIPLIHGSQGC ASFAKTFLTRHFWENIPVQTTALSQIATVMGNDDVLHTALKNVIERAKPEVVAVITTG VTETRGDYTEGSIKLFRELYPDFRHVEILCVHTPDYEGSFHTGYKEALLSIVKNVVRT KYATVPDQVNLIVSYSLTAEDIDTLKELLELFGLKVIVLPDISMSMDGGVLGFSSVIP NGTALRDIQRMSSSTITIAVGESAKAAGEYLEKEFMIPMYYFEHLMGIESYDELIRLL INLTGRDLPERVKRWRNRLLDMMIDSHFYLSKKRVAIAGEPDYIIGLSQFLAKELGMV VSLAVTTVKTESLETLPVEDIIVGDLEDILNSKKDFDLLIGNTNLRHVASKLNVPHYR VGIPIFDRLGHFLKGFIGYKGSTYFTMDIANLLMEREEEESYRVPDYVKRRYEQC" gene 7906..8292 /gene="" /locus_tag="" /db_xref="423682..424068" CDS 7906..8292 /gene="" /product="nitrogen fixation protein NifX" /translation="MLRVAFATKSLDKVDDHFGHARVFAIYDVGPTGYSFVEYRYFED IPDEEYDKINSKVEKLMDCSIVYVIAIGATAAARIVKHKIHPVKVNEPTPIEDIVNKL VETLNSNPPPWLKKALMDSKEKLMEG" gene 8296..8724 /gene="" /locus_tag="" /db_xref="424072..424500" CDS 8296..8724 /gene="" /product="TOBE domain protein" /translation="MKLAARNKFSGIVNDIERGRVVSKVSVMLKNGEIIKSIITTEAV ESLKLEVGRDVFVIIKATDVMLGVPEENDAPSLSARNIMKGTVKAVTEHNINSIVKVD VGGLTFTSFITTEALKELGIKEGMEIFVIVKASNVIISIQ" gene 8745..9026 /gene="" /locus_tag="" /db_xref="424521..424802" CDS 8745..9026 /gene="" /product="protein of unknown function DUF683" /translation="MCVSKLSLDMNMEREREDLESVYSKMSLEELKEEVKKLRMMAVQ SATKLHDLAEEGLPNRWREIPSVAKEAYEIHRKYFVAKTIFEKRSKEGG" gene complement(9023..10597) /gene="" /locus_tag="" /db_xref="424799..426373" CDS complement(9023..10597) /gene="" /product="CTP synthase" /translation="MAKFIFVTGGVLSSLGKGVTSAAIASLLEEMGYKVTLQKLDPYL NVDPGTMSPYQHGEVFVTEDGAETDLDLGHYERFTNARMGRWNNVTSGRVYFNVIQRE RKGEYLGMTVQVIPHITEEIKRLIRSIEEDKDVVVVEIGGTVGDIESLPFLEAVRQMG LEVGRENAVYIHVTYVPYVKSAGELKTKPTQHSVKELRAIGIQPDVIVCRSEIEIPDS IKEKIALFTNVNKSAVISAPDVEFIYEVPIIFRKQDLHRWLTRRLGLEFREVPSRWDR IVHILKHAQRKVKVALVGKYVALRDAYKSVVEALTHGGIANDARVEILWINSECVREE DLKEADGILVPGGFGERGIEGKMLALRFGRVSGKPTFGICLGMQLMCVEFARSVLKLE RANSTEFDPYTPYPVIDLMEDQKNIEELGGTMRLGAYPCVLAEGSKARAIYGKEIVYE RHRHRYEFNNAYRDIFQKEGVVFSGLSPDGKLVEIIELKDHPWYIGCQFHPEFKSKPF EPHPLFASFIKACLGD" gene complement(10609..10824) /gene="" /locus_tag="" /db_xref="426385..426600" CDS complement(10609..10824) /gene="" /product="thiamineS protein" /translation="MVRIEVLYRGRKVELHFEKDKVTADDVLKALGLSRQYAFVVKNG EVVSEEEPIKPEDQVRVINAISGGKNL" gene complement(10793..12007) /gene="" /locus_tag="" /db_xref="426569..427783" CDS complement(10793..12007) /gene="" /product="protein of unknown function DUF224 cysteine-rich region domain protein" /translation="MEKLVEIPLDLAQKCVKCGLCKSVCPTYRQEEGSYARGRLALAE MVVKGDLPLTQEVAKQWDECAMCRRCEWICPNDVQYKEIMAFARHHQKKKLGMGLVKR MALKSLMLLQSPLGRKVVPILGKILRLLPAEGLRIIFPTGARKFMPKASPSAFELRGK VFQADQEKGKLLFFTGCMIDAFYTETGRNVIKLMNRAGYTVIVPEDIRCCGAPHYYSG DMESFTQLKEHNMKEMSKYQYDAVVVACPTCGGALKEDYGIDKDVFDFTQIIQKNPLP FKGNGERVTFHVPCHSYTAMKLKEEVFYDTLKMVKNAEVRKASKDKSCCGFAGIFSIT NPALSDKIQKEKMDDLLKTEAQVVLTTCPGCVLQLTDGTRKYGKCQKVMHLADYLAQR LHDGEDRGSLQR" gene complement(12016..13278) /gene="" /locus_tag="" /db_xref="427792..429054" CDS complement(12016..13278) /gene="" /product="peptidase M16 domain protein" /translation="MIIILLFLSFLGISYGGGKVHYLTLKNGVRIIVEETHGRGIVSG SIFIKGGTHGEKKRGTTHLMATLLIRGTKSYDAYSIASTFEDWGGSISTSTADDYVEI SFSTRPQGFEKALEVIKSILTEPLFSQDDLSREKNNTIVAIRASRERGFDFAMEHLRR ITYRGTSYEVSPLGREEDIQNITREDLLERWRQLVKGGNVVVSISGDISWDQVRGKLE EAFSSLPAGSYPVDTVSTYIEETKLEKVEREGSQATIMCAFNAVPYNSKDYFAFKVLT SILGDGMNSKLFKELREKKGYAYATFAMYPTRLASPRLIAYIGTSPQKAQDALQDLVK VILHSPIEEGDLQLAKKRMVGDYILDHQTRARRAWYRGFYEVLGLGYKTDDEYVSRIQ EVRWEDIKRLRENLGDKYHCVVVQPPKI" gene complement(13275..14567) /gene="" /locus_tag="" /db_xref="429051..430343" CDS complement(13275..14567) /gene="" /product="peptidase M16 domain protein" /translation="VLVLLIVLLEVVVMSVSFATTQLKVYKLSNGATLIVNPRDDTTA VSLQVWFRVGSIYENYQQKGMAHFLEHMLFNGSEEYPYGEIDRLVEEMGGDINAGTSK DYTFYYITVAQPYWQQALRLLYQLTQKPLLQEQMVEKEKPIVIEELRRGKDNPSNVLW EELEKLAYKVSPYRFPIIGFEETIQKFNREMLLEFFRNFYQPQNMYVVVVGDVDPQEV LKVTEETFGKETGRRVPFSDFLPEPDWSQNRFKKLEDPRLERAMWAIAWKTVPAGEKE YYALVVLDQILGGGRTSLFYRELREKGLVYSVSTGDMGRPRDNLYVIYATFDPSKYQE VKERIFKLMQDLSTNLSDEDVEKAKERIINGEVFTQEKPQREAYFIGYSATVIGRLDY YLYFENNIRSVRKIDVLRVLERYFLGRPYVELLMVPKR" gene 14569..15108 /gene="" /locus_tag="" /db_xref="430345..430884" CDS 14569..15108 /gene="" /product="hypothetical protein" /translation="MIILCNVVIVVVMGLSGSGKSYLAKLLHRYWGFEWIRSDEIRKK LAGIEPTKHVREAFGEGIYSQDWTERVYSQMVKMAEDLVKEGKKVVLDATFLKEWQRE LVKSAFPDAIFLLAEASDETIRRRLREREDISDATEEIYLKQKEVFERPSYAVVVNTE KSEEELRELLQNLLSAKGV" gene complement(15065..16177) /gene="" /locus_tag="" /db_xref="430841..431953" CDS complement(15065..16177) /gene="" /product="peptidase S41" /translation="MNLPIFLLLILLQLAYSQETCSREETLQRLREYIQRYYLWKEKL GPLPTWQDESEAIQFLRQKGDKWTTITNIEEDRSWYSEGKLVGIGIRWDDKGQVVRVF RGSPAEKAGIRPGDIIYSINGERDNTKWSVVIRNTPAEKPVELVLIRNGLFVTVDVYK GPFVVDPIEDVKVLEFMGKKLGYIHLVNFTMPALREFSAALEKLISEGIDGLVLDLRN NSGGLISVAKGIADTLIGGEGVMFYLESAGNGVVLYEFSNRKGIGMPILVLVNRNTAS AGELLTALLKRYAKAVVAGENTFGKYVGSNVYPLNSCGKVVRLVTFVMKLPDGSPIAP DGGIRPDCPLGKDDSLSSALKCIKPLLPKEDFAITP" gene 16244..16639 /gene="" /locus_tag="" /db_xref="432020..432415" CDS 16244..16639 /gene="" /product="hypothetical protein" /translation="MEKMLVFLNSLYLGMASFFSFYVAPTLFKVLGKEQAGKVVEKVF PVYFGVGGLVALLSVLLGFRIGKFFVLLAILNLLLHILQEFYILPTANQLKQSNYEEF MRWHGISVSVNLAILVITLLMVVIILRKL" gene 16642..17001 /gene="" /locus_tag="" /db_xref="432418..432777" CDS 16642..17001 /gene="" /product="Crossover junction endodeoxyribonuclease" /translation="LYISTLPVPKSNRYIRRRGGKVFKPPRIKNWEVRALWEIKQQYS GSTLLGPLRMEVELTLPNRRKRDIDNMLKSLWDILEKAKVIGNDDQIQELYVIKRYSK GQQGTKIRIIEGISDTQ" gene complement(16973..18232) /gene="" /locus_tag="" /db_xref="432749..434008" CDS complement(16973..18232) /gene="" /product="Peptidase M23" /translation="MRRGVFLLGISLLITLAWGKECKFHKVRKGDTLESIAREYGVSL SDIKRYNKNLKENRLKVGQQICIPVKTKAEKKQGDYAIYRVKKGDTLEEIAQKFGVDV KELAKFNGLKSHVIKEGQELKIPARSHGEKVSKKGKEVDYTTYTVKKGAKLQHVAQKL GVPLRELEKLNPELKGKWLKPGTVVKIPKKMKEEKVAEKVEKVSKKGEEVDYTTYTVK KGAKLQHVARKLGVPLRELEKLNPELKGKWLKPGTVVKIPKKMKEEKVAEKVEKVEKK TEREKIPTVEERETPPPPPVEKKISIGKLPMPVEGKIEKAQRGVQIVGNCDQKVRAVE SGKVIYSGDDLKAYGNMVIVDHGSFISLYANNSTNLVRRGDTVEKGQAIAVIGKDKDS GRCVLHFELRDKDGIPLNPTEYLRSLQ" gene complement(18201..18476) /gene="" /locus_tag="" /db_xref="433977..434252" CDS complement(18201..18476) /gene="" /product="acylphosphatase" /translation="MLVAYRVYLRGVVQGVGFRAFTRKVAESYALDGWVRNLPDGRVE IWVQGDKDVVWQFLKEVSEGPRGARVDVMEIVKEVPQHEERGFSVRY" ORIGIN 1 atgggtgtac tagttgataa agaaacagct ctcaagatca tagaggaagt actaagcgct 61 tatcctaaga aagccaaaaa agacagggag aagcatatag ccgtagtgga acctcaagat 121 gataagtgta ctccaaagtc taacatcaaa tcaagaccgg gcgttatgac cgtaagagga 181 tgtgcttatg cgggttcaaa gggtgttgta tggggaccaa taaaggatat gatacacata 241 tcgcatggtc cggtaggttg tggttactac tccagagctg gtagaaggaa ttactatata 301 ggtacaacag gtgtagatac ctttgtgaca cctcacttta ccacagactt tcaggaaagg 361 gatatcgtat tcggcgggga taaaaaactt atgaaagcca ttgaagagtt gaacactctc 421 ttccctcttg caaagggtat aaccatacag tcggagtgtc ccatagggct tataggagat 481 gatattgaag ctgtggcaag gatggcctcc aaaaagatag gaaaacccgt aattccagtg 541 aggtgtgaag gttttagagg ggtgtcccaa tctctggggc accatatagc aaacgatagt 601 atgagagatt ggatatacga aaaaggttta aagggtcaag agatagaatc cacaccttac 661 gatgtggcaa tatggggaga ttataacata ggtggtgatg catgggcaac gagaaaaata 721 ctggaggata tgggactcag agtcattacc cagttttcag gtgacgggac cttttctgaa 781 gtggcaaatg ctgtaaaggc gagatacata ctcgtacact gttatagatc ctccaactat 841 ctggcacgct acttcgaaga gaagtttggt atcccatgga ttgagtacaa cttcttcggt 901 cctactcaga tatttgcctc catgcgaaag atagctgccc tctttgatga taagatagtt 961 gaaagaaccg aagagcttat agagaaggtt tataagccga gactggatcg tgtaatagag 1021 aaatacagac caagactaga aggaaagaca gttctcttgt atgtaggtgg tttaaggcca 1081 agacatatga tcacagcctt tgaggatctt ggtatgaacg ttatagctac tgggtacgaa 1141 tttgctcacc aagatgacta tcaaagaaca cttcactaca tagacaaaaa cactacgata 1201 ataatagatg atgctaccgc ttacgaaata gaggaactca ccagaaaact taacccagat 1261 ctggtagctt ctggaattaa ggagaagtat caagcccaga agatgggtaa gcccttcaga 1321 cagatgcaca gctgggatta cagtggtccg taccacggaa tagaaggttt tgagatcttt 1381 gcaagagata tcgatatggc agtaaacgga aatgtgtgga agtatataga agctccttgg 1441 aaaaaataat ttatggaggt aatcgccatg ggtatacatc atgagctaaa cataaaagat 1501 caccttgagt gttttagaaa tgatgaattt aggaatatga tcgccaacaa gcgaaagaac 1561 tttgaagatt gggtaggcga agagaaggtg aaagaagtgg cagaatggac aaagacatgg 1621 gagtacagag aactgaactt taagagggaa gccatctcca taaaccccgc aaaggcatgt 1681 caacctctgg gcgcgcttct gtgcgccctt ggttttgaaa gaaccctccc cttctctcac 1741 ggttcccagg gttgtgtggc ctatttcaga actcacatgg caagacactt taaagagcct 1801 gtacctatgg tttccacttc catgacagaa gatgccgcag tatttggtgg cttaaacaat 1861 atgcatgaag gactccagaa tgccatagcg ctctataaac ctaagatgat agctgtcagt 1921 accacatgta tggcagaggt gatcggtgat gacctcaaca gctttataac aacagcaaaa 1981 gagaaggggt taatacctga ggatttcccc atatgttttg ctcatacacc gtccttcgta 2041 ggatcccata taactggtta cgataatatg atgaaagcta tccttcagca tatgacatct 2101 tacttcgaaa agtacggagt tgataacata gacaaatacg atgaaaacgg agagttctat 2161 gaggagggtg gtttattagg ctggctccag aaaggtaaag gaggtgatta atatgagtgc 2221 gggtagagta aatatcatac taggttttca tacatactta gaggattata aagaggtaag 2281 aaggatagtg gaaaagtttg ggctagagtg catagttctc tctgatcctt ccgaaaatct 2341 aaactctggt ctcactggtg attacaaact gtactacggt ggcacccccc ttaaggatat 2401 atacagagcc aaatcttcta tggctaccat agtcttccag aagtactcta ccgaaaagac 2461 cagagagtac atagagaaag agtggaaaca gcctacttat gtggtaagac cttatggcat 2521 acagggaacg gatgagtttt taatgctact ttccaaactc tctggaaatc ctgtaccaga 2581 agaacttgaa cgcgagagac agttgctcct ggacgccata gcggactctt attactggat 2641 acacggcaag agatttgcgc tgtggggaga tccggacttc gtttacggac ttacatcttt 2701 cctcttagag ttgggagcag agcctgttca cattttgagc actaacggta acgaagagtg 2761 ggcggaagag gttaaggagc tctgttcgaa gtttgataat ggaaagtacg cacagttatt 2821 ccccggaaag gacctttggc atatgagaag tcttctgttt acggaacctg tcgattacat 2881 gataggtacc tcctacggaa agtacctctg gagagatacg ggtactcctc tcatacgtat 2941 cggttatcct atctttgaca ggcatcatct tcacagatac ggcatcctat tctacaaggg 3001 tgctctcaac atgctcgtat ggatagtgaa ctccatactg gatgaagtag acagaagaac 3061 aataggcatt gccactacag actatagctt tgatctcatc aggtaaataa gatgagtgtc 3121 gtagagaggt taaaaagata tatagaagag ggcctcgttg cggaacacac ctataaggtg 3181 ggagaggatc tgagttttga aaagggggtt tatgtggtaa aggagggggt catagagcta 3241 ttcaccttca agagaaaagg taaacaggta ctggatctcc tctttaaggg ggatgtaata 3301 ggctttctat tgaggaatac ttcccttacc aattacaagg ctaggccact caccccctcc 3361 accctcttct acatcaagga ggacgcgctt atcaaaatag gagagaagga accgcacctg 3421 gccctcgata tctttgcctc tttactttca aagcaggcct atctctacaa tgtactcacc 3481 atagtctttg caggtgatgc aacagagaag ataagagacc tcatgtgttt acttgaaagg 3541 cgcgcggaag aaaaaggtac atatcttacc cttaggaaga gccaaatagc aagtataaca 3601 ggactaagtt atgagcatgt tgtaagaaag atgaagtgta taagaataaa gaataaaaac 3661 gggaggataa gactatggtg ataaaaaagg aggacataga tcttggtgag gaagtattaa 3721 aagagatagt gcggcaagta agagcttacg atacatacgg aacatgggag aagaggaagg 3781 atgaagatat acttaaggag tttctcaaga catcttcaaa acagatcgca catgcaggag 3841 ggtcctgtag tctggaccca agagctatgc ttaaacttca tgcttatttc aaagcgttag 3901 gtgttatcat agaaagactt tcaggttacc taacttccgc agtgataaac atagaccatg 3961 aaggaaatgg aaccgttatt ctgtacgctg gcagactaat tctgataaat aaaagcataa 4021 gggatgccaa taactttggt ttcaaatcta cagataacat caaacaggaa gcggagaagt 4081 tgataaacaa agctttacaa cttatagaaa agtatgaaga ggtttgtaag atatgaggag 4141 gttgatacct ttcaaacctt acggttattc taaggaagat atgatatctg ccgttgaggc 4201 tatgggtcat ccttactgtt tctcgggact gagaagaaag gaattagaag attctttctg 4261 tcagtacagt ggcagaaaat acgccgttgc cacacgtgat gtcgttcctg gccttttggc 4321 tcttcttgag tacttaggtt tatcgtacgg agacacggtg gcctacactc ctctctcctt 4381 agctcctcat tttgctaaat acaccaagtt tatgggacta aactctgctt acgcagatgt 4441 agagaggtgg ttctttaacg ttgatgtaaa aagactgtcc aacgtaataa catcgtataa 4501 gccaaaagtt cttatagtaa acaattctct tggtatacct gcagattggg atgctgtaag 4561 agaactctta aaaggaacag gtatatttct gatagaagac tctagagaga cgcttttcag 4621 cgattataaa gggcgccctg caggctcttt gggtgacgtt tccttcttgg ctttttctcc 4681 caactctgtg ctgaggggtt acggaggagt aatactaacc gacgacgcac ttatttacaa 4741 aagaatcaga gagaaagtgg aacctatgga cgatataatg gcttcccttc ttatctccca 4801 aaccaaaagt ctggaagaga ggataaatat aagaagggag cttgcgcaac tttactccca 4861 gttgctgtca aacatggaag gtatgaaacc tcagtttttc cctaaatacg taaacaaacc 4921 ttgttggtca tatatgtgtg ttcatttagc aaaaagatac ggaagggatg cagtagacag 4981 tatcgtagaa ctaatgtggg acgatggtat agaaactcta aagtatcctg tgtcacagga 5041 tatacaggaa ggtaaaagta tgcctcacct acatatatct catgaggtaa gtacgagagc 5101 catactgttg cctcttcatg aggatatgga cgaggaggac gtgtactttg tctgtgagag 5161 gtttaaggat tatgtgatac agataggagc aggtagtgta gatcattgaa ggaggttgtt 5221 gccatgagaa acttagaaga gttttttaca gaacctgcgt gcggtattaa taaaagtaag 5281 ggagataaag agaaaaaagt tggatgctct aaaccaaaac caggaagtgc atccggagga 5341 tgtgcctttg acggtgctca gataacactt cttcccatag cggacgccgt tcatatagtt 5401 cacggtccaa tagcatgcgc tggaaactct tgggataaca gaggcacaag atcctcttca 5461 cctatcacct actataggat gggtttcacc actgacctct ctgagataga tgtgatacac 5521 ggaggtgaga ataaactgta tatggccata aaggaggcag tggaaaagta taaccctcct 5581 gctgtgtttg tataccaaac gtgtgtaccg gctatgatag gagacgatat acaggccatc 5641 tgcaacaagg cttccaaaga ttttaacata ccagttgtac ctgttgattc accaggtttt 5701 gtgggtagta agaatttggg caacaagctt gccggagatg ctttattcag atacgttata 5761 ggtacaaaag aaccggagta tacaacaccc tacgatgtga acttgttagg ggaatacaac 5821 atagcaggag aactttggca ggtgcttccc cttcttcagg aggctggctt tagaatacta 5881 gcgtgtataa ccggtgactc aagatacaac gacatagcaa cggctcatag agcgaaggta 5941 aatatggtag tatgttcaaa agcattactg aaccttgcaa gaagaatgga ggaaaaatac 6001 ggtataccgt actttgaagg ttcattttac gggataaagg acacaagtga tgccttgaga 6061 aacatggctc ttcttatagg tgacaaggac ctgatagaaa gagttgagaa gttaatagag 6121 gtaaaggaag cagagactaa ggaaaaacta aaaccctata tagaaaaact taagggtaag 6181 aaggtactta taaacaccgg tggtgttaaa agctggtcca tggtggcaca ggttcaggaa 6241 ctcggtatgg aggtggtagg taccagtgca aagaaaagca cagagggaga caaaggcagg 6301 atgttagaac ttttaggaga tgagaagaaa cttatagatg accctaaccc taaggagctt 6361 attaagataa tgagatcaga aaatgttgat ttactcttgg ccggaggtag aagcaagttt 6421 gtagccttca aggaaggtat accattcctt gacgttaacc aagagaggat aaggggatac 6481 gctggttatg agggtatgct tcttctagca gaagatatag ttagaacact ggaaaacccg 6541 gtatggaatc tcagaaggag gaaagcgcca tggcaagagt agtggagagt aaaaaggcac 6601 tgtccgtata tccccttaag ttgagtcagc ctctaggagc tatgtatgcc tttatgggtg 6661 taaaaggaag tataccacta attcatggat ctcagggctg tgcctctttc gcaaaaactt 6721 tcttaacaag acacttttgg gaaaacatac cggtacaaac tactgcctta tcacagatag 6781 caacggttat gggaaacgac gatgtactac acacagccct aaagaacgta atagaaaggg 6841 caaaacctga agtggtagct gtaatcacta ctggggtcac ggagacaaga ggagattata 6901 cagaaggttc tataaaactc tttagagagc tttaccctga tttccgtcat gtagaaatac 6961 tttgtgtgca cacacctgac tacgaaggat cctttcacac gggctataaa gaggcccttc 7021 tttccatagt aaagaatgtt gtgcgtacaa agtatgcaac ggtaccagat caagtaaacc 7081 tgatagtaag ttacagcttg actgccgagg acatagatac tttaaaggag cttttggaac 7141 tttttggttt aaaggtaata gtattacctg acatatccat gagtatggat ggaggtgtgc 7201 tgggcttttc ttcggtaata ccaaatggaa cagcactgag ggatattcaa agaatgagtt 7261 cttctaccat aaccatagcg gtgggagaga gtgccaaggc tgcaggtgag tatttagaga 7321 aagagtttat gatacctatg tactactttg aacatcttat gggaatagag agttacgatg 7381 agttgataag attgcttatt aatctaacgg gccgtgatct gccggaacgt gtcaagagat 7441 ggagaaacag attactggat atgatgatag acagtcattt ttacttatct aaaaagcgag 7501 tagccatagc gggagaacca gattacatta taggactgtc tcagttcctt gcaaaagagt 7561 tgggaatggt agtttcgttg gctgtcacca ctgtcaaaac tgaaagttta gagaccttac 7621 cagtagaaga catcatagtg ggtgaccttg aagatattct taacagcaaa aaggactttg 7681 acttactgat aggtaatacc aatctaagac atgtagcttc taaactgaat gtacctcatt 7741 acagagtggg cattcccatc tttgacaggt tgggacactt tctgaaaggt tttatagggt 7801 ataaaggttc cacttacttt accatggata tagcaaatct tcttatggaa agggaagaag 7861 aagaatctta cagagttcct gattatgtca agaggaggta cgagcaatgt tgagagtggc 7921 ttttgctaca aaaagtctcg ataaggtgga cgatcacttt ggacatgcta gggtgtttgc 7981 catatacgac gtgggaccca caggttacag tttcgttgag tacagatact ttgaagacat 8041 acctgatgaa gagtacgaca agataaactc taaagtagaa aaactgatgg actgttccat 8101 agtttacgtt atagcgatag gggcaactgc ggccgcaaga atagtaaagc acaagattca 8161 tcccgtaaag gttaacgagc ctactcctat agaggacata gtgaataagt tagtagaaac 8221 cctgaactct aatccgccac cttggttgaa gaaggcactt atggacagta aggaaaaact 8281 tatggaaggt taagagatga aacttgcggc aagaaataag ttctctggta tagtcaacga 8341 tatagaaaga ggtcgtgtgg tttcaaaggt ttcagtaatg ttaaaaaacg gtgagatcat 8401 aaagtccata atcactacgg aggctgtaga atctttgaaa ttagaagtag gaagagacgt 8461 attcgtcatc ataaaggcca cagatgttat gctgggggtt cctgaggaaa acgatgcccc 8521 gtcactgagt gctaggaata taatgaaggg aactgtcaaa gctgtaacgg aacataatat 8581 aaacagtata gtaaaagtgg acgtaggtgg gctgacattc acatctttta taactacaga 8641 ggctcttaaa gagttgggaa taaaggaagg aatggagatt tttgttatag taaaggcttc 8701 caatgtaata atatcgattc aataaataag taaggaggtg tagccatgtg tgttagtaag 8761 ctgtccttgg atatgaatat ggagagagag agggaagact tggaaagtgt gtactccaag 8821 atgagcctag aggagctaaa ggaagaggtg aaaaagttaa ggatgatggc cgttcagagc 8881 gctacaaaac ttcacgatct tgcagaggag ggacttccta acaggtggag agaaatacct 8941 tccgttgcaa aggaagctta cgagatacac agaaagtact ttgtagctaa gactattttt 9001 gagaaaaggt ccaaagaagg aggttaatcg cccaagcatg cctttatgaa ggatgcaaat 9061 agaggatgtg gttcaaaggg tttactctta aactcagggt gaaactgaca tcctatgtac 9121 cacggatgat ctttgagctc tatgatctcc accaacttgc cgtccggtga aagccccgag 9181 aacactacac cctccttttg gaatatgtct ctgtatgcgt tgttaaactc gtacctgtgg 9241 cggtgtcttt cgtaaactat ctccttgccg tatatagccc ttgccttgct tccttctgca 9301 agcacacacg ggtaagctcc taacctcatg gtcccaccca gctcttctat gtttttctga 9361 tcctccataa gatctattac agggtaaggt gtgtaaggat caaactcggt ggagttggct 9421 ctctccaact taaggacact gcgagcaaac tccacacaca tgagttgcat acccaaacat 9481 ataccaaagg taggtttacc ggacactctt ccgaaccgta gtgccagcat cttaccctct 9541 atgcctctct ctccgaaacc acccggaacc aaaataccgt ccgcttcttt tagatcctcc 9601 tccctcacac actcggagtt tatccaaagt atctccactc tcgcatcgtt ggctatgcct 9661 ccgtgagtta aagcttccac cacactctta taggcgtctc ttagagctac gtacttaccc 9721 acaagagcca ccttcacttt tctttgggca tgcttcaaga tgtgtactat tctgtcccac 9781 cgggagggca cttctctgaa ctccagtcca agtcttcggg tgagccagcg gtgaagatcc 9841 tgcttcctga agatgatggg aacctcgtat ataaactcca cgtcgggtgc ggagataaca 9901 gcagatttgt ttacgttggt aaagagagct atcttctcct tgatggagtc gggtatctct 9961 atctccgatc tacatacgat tacatctggt tgtatgccta tggctctcag ttccttcacc 10021 gagtgttgtg tgggttttgt ctttagctca ccagcgctct tcacataggg tacatacgtg 10081 acgtgtatgt acaccgcgtt ttctctgccc acttcaagac ccatctgcct gacggcctcc 10141 aagaaaggca gactctctat atctcccacc gtacccccta tctctaccac caccacatcc 10201 ttatcttcct ctatggacct aatgagtctc tttatctcct ccgttatgtg gggtatgacc 10261 tggactgtca ttcccagata ctcacccttt ctctccctct ggatgacgtt aaagtaaacc 10321 cttcctgatg tcacgttgtt ccatcttccc atacgggcgt tggtaaagcg ttcgtaatgc 10381 cctaagtcta gatctgtctc tgcgccgtcc tctgtaacga aaacctctcc gtgctggtaa 10441 gggctcatgg tacccggatc tacgttaagg tacggatcca gcttctgaag ggtgacctta 10501 taacccatct cctccaaaag ggaggctatg gctgctgagg tgacaccttt ccctaaggaa 10561 gacagaacgc cacccgtcac gaatataaac ttggccatgt gagaatattt tagaggtttt 10621 taccacccga gatggcgttt atgaccctta cctggtcctc cggttttata ggttcttcct 10681 cactgaccac ttctccgttt tttaccacaa aggcgtactg tctagataat ccgagagcct 10741 tcagtacatc atctgcagta actttgtcct tttcaaaatg caactctacc tttctacctc 10801 tgtaaagaac ctctatcctc accatcgtga agcctctgag ccagataatc agccaagtgc 10861 attaccttct gacacttccc gtattttctg gttccgtcgg tcagttggag tacacaaccg 10921 ggacaagtgg ttagaaccac ctgggcctcc gttttgagaa ggtcatccat cttctccttc 10981 tgtattttat ctgacagggc aggattggtt atggaaaaaa tacccgcaaa accacaacaa 11041 gatttatctt tgctggcttt tctaacttca gcgttcttta ccatcttcag ggtgtcgtaa 11101 aaaacctcct ctttcagctt catggcggtg taagagtgac acggtacgtg aaaggtcacc 11161 ctctcaccgt ttcctttaaa aggaagaggg ttcttctgta ttatctgggt aaagtcaaaa 11221 acatccttgt ctataccgta atcttcctta agtgcaccac cacaggtagg acaggctact 11281 accactgcat cgtactggta tttactcatc tccttcatgt tatgttcctt cagttgggta 11341 aaactctcca tatcacctga gtagtagtga ggcgctccac aacaccttat atcttccggg 11401 actatcaccg tataaccagc tctgttcatc aactttatta cgtttctgcc tgtctctgtg 11461 taaaaggcat ctatcataca acctgtgaag aagaggagct tacctttctc ctgatccgcc 11521 tgaaagacct taccacgcaa ctcaaaggcg gagggagatg ccttcggcat aaacttgcga 11581 gcccccgtag gaaagatgat acgcaaacct tctgcaggaa gtagtcgaag tattttccct 11641 aggatgggaa ctacttttct gcccaacgga gactgtagta acataaggct tttcagcgcc 11701 atcctcttta ccagacccat acccagtttt ttcttttggt gatgtcgcgc aaaggccatt 11761 atctccttat actgaacatc gttggggcat atccactcac accttctgca catggcacac 11821 tcatcccact gcttggctac ttcttgggtg agaggcagat ctccctttac caccatctct 11881 gccaaagcca acctaccccg tgcgtaagat ccttcctcct gtcggtaagt aggacatact 11941 gacttgcaga ggccacactt tacgcacttt tgtgctaaat ccaaaggtat ctctaccaac 12001 ttttccatag tctttattaa atcttgggtg gttgcaccac cacgcaatga tacttatcac 12061 ctagattttc cctcagacgc tttatgtcct cccacctaac ctcctgtatc cgtgaaacgt 12121 actcatcatc cgttttgtaa ccaagaccta acacctcgta aaagcccctg taccaggctc 12181 ttctggctct tgtttgatgg tcaaggatat agtcgcccac cattctcttc ttagccagct 12241 gaagatctcc ttcttctata ggagaatgta agatcacttt caccaggtcc tgaagtgcat 12301 cctgtgcctt ttggggagaa gtgcctatgt aagctataag acggggagat gcaaggcgtg 12361 ttgggtacat ggcaaaggtg gcgtaagcat agcccttttt ctccctcaac tccttaaaaa 12421 gctttgagtt catcccatca cccagtatag aggtaaggac cttgaaagca aagtagtcct 12481 tagagttgta aggaactgcg ttgaaagcgc acattatggt tgcctgagat ccttccctct 12541 ccaccttttc taacttggtt tcttctatat aagtgctcac cgtatccaca ggataactac 12601 ctgcaggtaa agaagaaaaa gcttcttcca attttcctct cacctgatcc caacttatgt 12661 ctcccgatat gctcaccacc acgtttccac cttttacaag ctggcgccac cgctcaagaa 12721 gatcttcccg tgttatgttc tgtatgtcct cttctcttcc taaaggagat acttcgtagc 12781 tggttcctct gtaggttatc cttcttagat gttccatggc aaagtcaaag cctctctctc 12841 tgctggccct tatagcaact atggtgttgt tcttttccct actgaggtca tcctgcgaga 12901 agaggggttc tgtcagtata ctctttataa cctcaagagc cttttcaaaa ccctgtggtc 12961 ttgtagaaaa gcttatctcc acgtaatcat ctgccgtgga ggttgatata ctacctcccc 13021 agtcttcaaa ggtactggct atactgtaag cgtcgtagct tttagtaccc cttataagga 13081 gagtggccat aaggtgtgtg gtgcctctct ttttctctcc gtgggtaccc ccttttatga 13141 agatactgcc gcttactata cccctgccgt gagtctcttc cactatgatg cgtacaccgt 13201 ttttgagggt cagataatgc accttaccac ctccgtagga gatacctaaa aaactcagga 13261 aaaggagtat tataatcatc tcttaggtac cataaggagt tccacgtaag gccttcccaa 13321 gaagtacctc tctaaaaccc gaagaacgtc tatcttcctt acacttctta tgttgttttc 13381 aaagtaaaga tagtaatcca atctccctat gactgtagca gagtatccta tgaagtaagc 13441 ctctcgctga ggtttttctt gagtgaacac ctcaccgttt attatccttt ccttagcttt 13501 ttccacatcc tcgtcagata ggtttgtact gagatcttgc ataagcttaa agatcctttc 13561 ctttacctct tggtatttgg aaggatcaaa ggtggcataa atcacgtaaa ggttgtcacg 13621 aggccttccc atgtcccctg tagacacact gtaaaccaaa cctttctccc tcagttccct 13681 gtagaagagg gatgttcgtc ctcctcccag aatctggtcc agcaccacga gagcgtagta 13741 ctccttctca ccagccggaa ctgttttcca ggctatagcc cacatagctc tctctaatct 13801 cggatcttcc aacttcttga aacggttctg agaccaatca ggttccggta aaaagtcgga 13861 gaagggaact cttctgcccg tctccttacc gaaggtttct tctgtcacct tcagcacctc 13921 ctgaggatcc acatctccca ccaccaccac gtacatgttt tggggttggt agaagtttct 13981 gaagaactca agaagcatct ctctgttgaa cttctggatt gtctcttcaa agcctatgat 14041 gggaaagcga tagggtgata ccttgtaggc cagtttttcc agctcttccc acaacacgtt 14101 ggaggggttg tccttgcctc ttcttaactc ctctatgacg atgggctttt ctttttccac 14161 catctgctcc tgcagtaagg gtttttgggt gagttggtaa agtaatctca aagcctgttg 14221 ccagtaaggt tgcgccacag tgatgtaata gaaggtgtag tctttggaag ttcccgcgtt 14281 tatgtcgcca cccatctctt ccaccaacct atctatctca ccgtaaggat actcttccga 14341 accgttaaag agcatgtgtt ccagaaaatg agccataccc ttctgttggt agttctcgta 14401 aatggaacct accctgaacc acacctgtag agacaccgct gtggtgtcgt ccctaggatt 14461 cactatgagg gtggctccgt tgctgagttt gtacactttc aactgagttg tggcaaagct 14521 aacactcata accactacct ccagaagcac tataaggaga accagcacaa tgataatatt 14581 atgcaatgtt gtgatagtgg tggtgatggg tctttcgggg agcggtaaat cttatctggc 14641 caagttgctc catcgttact ggggtttcga atggataaga agtgacgaga taaggaaaaa 14701 actggccggg atagaaccga caaagcacgt aagggaggcc ttcggtgagg gtatatactc 14761 tcaagactgg accgagaggg tatatagtca gatggtgaag atggctgagg atctggtgaa 14821 ggaggggaaa aaggtggtac tggacgccac ctttttgaag gagtggcaga gagagttagt 14881 aaaatcggct ttccctgatg ctatttttct actggccgag gcaagtgacg agaccataag 14941 gcgtaggttg agggaaagag aagatatctc cgacgccaca gaggagatat acctaaaaca 15001 gaaggaggta tttgaaagac cttcttacgc ggtggtggta aacacggaga aaagtgaaga 15061 ggagcttagg gagttattgc aaaatcttct ttcggcaaaa ggggtttgat acacttcaga 15121 gcagaggaca gagaatcgtc ctttcctaaa ggacagtctg gccttatgcc accatccggt 15181 gctatggggg aaccgtcggg caatttcatg acaaaggtca ccagcctcac caccttccca 15241 caggagttaa ggggataaac gttacttccc acatactttc cgaaagtgtt ttcacccgct 15301 acaaccgctt tggcatacct tttgagaagg gcagtgagta gttcacccgc tgacgctgtg 15361 tttctgttaa cgagaaccaa aataggcatt ccaatgccct ttctgttact gaattcataa 15421 agaacaacgc cgttacccgc cgactctaag tagaacatca ccccctcacc acctatcaga 15481 gtgtccgcta tacctttggc caccgatatg aggcctccgc tgttgtttct tagatccagt 15541 acaagaccat ctataccttc tgatatcagt ttttctaaag ctgcagaaaa ttcccttaac 15601 gcaggcattg taaagttaac gaggtgtatg taacccagtt tcttacccat gaactccagc 15661 acctttacgt cctctatagg atccaccaca aagggccctt tgtaaacatc aacggtgacg 15721 aaaagaccgt tccttattag gactagttct acgggctttt cagcaggggt gtttctgatg 15781 acaacactcc acttggtgtt gtctctttcg ccgttgatgg aataaatgat atctccgggc 15841 cttatgcctg ccttctcagc aggggagcct ctgaaaaccc taaccacctg acctttgtca 15901 tcccacctta taccaattcc taccaacttt ccttcagagt accaactcct gtcttcctct 15961 atgttggtta tggtagtcca cttatcaccc ttctggcgga gaaactgaat agcctctgat 16021 tcatcctgcc acgtgggtaa aggacccagt ttttccttcc acaggtagta tctctgtatg 16081 tattccctca gtctctgcag tgtttcctct ctggagcaag tttcctgact gtaagctaac 16141 tgaagcagta tgagaagtag gaaaatgggc aggttcatag ctccgcagta tcctaataat 16201 aacatctgtg gtgccttttg gcaacgctgt taaaataaaa gactatggag aagatgctgg 16261 tttttctcaa cagcctctat ctgggaatgg cttccttttt cagtttctat gtggcaccta 16321 ccctctttaa ggtattaggc aaggagcagg cgggcaaggt ggtggagaag gtgtttcccg 16381 tttactttgg tgtaggtggc cttgtagcac ttctgtccgt ccttttgggt tttcggatag 16441 gtaaattctt tgtccttcta gccatcctca atttactact gcacatactg caggagtttt 16501 acatacttcc aacggcaaac caacttaagc agagtaacta cgaggagttt atgagatggc 16561 acggtatatc ggtgagcgtg aatctagcca ttctggtgat aaccctcctc atggtggtga 16621 taatactcag aaagttgtag agctgtacat atccacactc cctgttccta aaagcaacag 16681 atacataaga aggcgtggtg ggaaggtttt taaaccacct cgtataaaaa actgggaggt 16741 gagagccctc tgggagataa aacagcagta ctcgggaagt acccttttgg gaccattacg 16801 gatggaagtg gagcttacac tacccaaccg gaggaagagg gacatagaca acatgctaaa 16861 aagcttgtgg gatattttag aaaaagcaaa ggttataggc aacgacgatc aaatacagga 16921 actttacgtc ataaaaaggt actctaaggg gcagcagggt actaagataa ggatcattga 16981 agggatctca gatactcagt aggattaagg ggtataccat ccttgtctct aagttcaaag 17041 tgaagaacgc accttccaga atccttatcc tttcctatca ctgctatagc ctgtcccttt 17101 tccaccgtgt ctcctctcct taccaggttg gtggagttgt tggcataaag ggatataaag 17161 ctaccgtgat ctacaatgac catgttaccg taagccttaa gatcatctcc gctgtatatc 17221 accttccctg actcaacagc tcttaccttc tgatcacagt ttcctactat ctgcacaccc 17281 ctctgagcct tttctatctt accctctaca ggcataggca gtttccctat gcttatcttc 17341 ttctctaccg gtggtggagg tggtgtctcc ctctcttcca ccgttggtat tttttccctc 17401 tctgttttct tttccacttt ctctaccttt tcagccacct tttcttcttt cattttttta 17461 gggattttta ccaccgttcc cggctttagc cattttcctt tcagctctgg gtttagcttt 17521 tccagctctc tgagcggtac acccagtttt cgagccacat gctgaagctt cgcccccttc 17581 ttaacagtgt aagtggtgta atcaacctct tctccttttt tactgacctt ttccaccttt 17641 tcagccacct tttcttcttt cattttttta gggattttta ccaccgttcc cggctttagc 17701 cattttcctt tcagctctgg gtttagtttt tccagctctc tgagcggtac acccagtttt 17761 tgagccacat gctgaagctt tgcccccttc ttaacagtgt aagtggtgta atcaacctct 17821 ttcccttttt tactgacttt ttccccgtga ctacgtgccg gaatcttcag ctcttgacct 17881 tcctttatga catgagattt tagtccgttg aatttggcca actcctttac atctacacca 17941 aacttctgag ctatctcctc aagggtatca ccctttttca ccctgtagat ggcgtaatct 18001 ccttgttttt tctctgcctt tgtctttaca ggtatacata tctgctgacc taccttcagc 18061 ctgttctcct taaggttttt gttgtaccgc ttgatatcgg atagagatac gccgtactct 18121 cgagctatac tctccaaagt gtcacctttt ctcactttgt ggaacttaca ctctttcccc 18181 cacgctaaag ttataagtaa gctaatacct aacagaaaaa cccctctcct catgctgagg 18241 cacctccttt actatctcca tcacatctac cctagcgccc ctcggacctt ctgacacctc 18301 cttaagaaac tgccacacca catccttatc tccctggacc catatctcta ctctaccgtc 18361 gggtaggttc ctcacccaac catcgagagc ataactctcc gccaccttcc tagtgaaggc 18421 tctgaaaccc acaccctgca ccacaccccg caagtacacc ctataagcca ccaacat //