LOCUS NC_012622:25 17672 bp DNA linear BCT 04-SEP-2013 DEFINITION Sulfolobus islandicus Y.G.57.14 chromosome, complete genome. ACCESSION NC_012622 SOURCE Sulfolobus islandicus Y.G.57.14 chromosome, complete genome. COMMENT locus start: 2662428; locus end: 2680099 COMMENT n1_4mer:GRV/n1_4mer:RV = 2.590913; n0_4mer:D = 19.728842; n0_4mer:PS = 37.376051 FEATURES Location/Qualifiers source 1..17672 /organism="Sulfolobus islandicus Y.G.57.14 chromosome, complete genome." gene complement(-2316..32) /gene="" /locus_tag="" /db_xref="2660111..2662459" CDS complement(-2316..32) /gene="" /product="hypothetical protein" /translation="MRRERRLQVVEIIVVILLSILTPMIALWKVFFHVGYIYQRDSYP TFYLDSRQAALSYLNFPMIIDNVWMPLVVILYFNFISPVIAYWITYLLFPYAISVPSM YFSSRYFLNKYAKETKLWIKISVSSTIAFLYAITPTAYYFSHWSNYAAFYALLPALIA GTFYSLEKGGLSGAILLSLFASLTTTDPRGFVYTLFIILSILIYRHKLNDLKVFLYSI PFYLLLNSRLFVVLFYNFHSYSSISFTISNQQLWLNYFTFPLLDSLRGLSLFRPLVSY LSFGNPLLIYVMSFAFVETGILGYIFLKKKGSPANYFLALYLFLVFLVSSYVNVLGYN IMLNLTYPLLDFLAQTFVYSYLWLFLPTYLTEMILAPLFLLVSLVMAKILSKHYLIPL FILIVLSQFTFSSSMVISGDYLGNYNPVNPPPLLVNLAKFLENNTIGNVLVDAIVPSN WSTFIEVLPNVTSAFLVNTSSVGTILNEYGIQYVVSTVNDNYTLSIINSHKNVFTLVY NDSYFLVYKNNDFTYNINSPIFINFEYPKIPNTNSSLNVVPSYLMFDIPPKYIGGYFG NVTYAELLALSAYKQGILPVKLNVKHLPYPNNFTDTINVNVYDEEILSEFPSISFISV SNTSFLNLGVKPGFYKVVLVYVSLPGGGVFGVTNGSYSLSVSTSSPNISIVFSYLGNI SVSSSVKLFFIGNSLSYLIGVMFIPYNISIQNELNGNNISSYPYPQLGRAFGYPYNDN NVISFSIMINLITLLITVILFISLLYARTYFRKITLKIFHHN" gene complement(1..696) /gene="" /locus_tag="" /db_xref="2662428..2663123" CDS complement(1..696) /gene="" /product="hypothetical protein" /translation="MSSPLLFLLIIALFPNAFVEYSLHIQINYDNQVYHLSELLFENV TRVCYNNATFAYNLTVYVLNFSQILTSSTILDNVSLPETFFYIPNVGEPVIERGVILS LLSSNNSNYVYYGKTFIGYIELEYFYYVNSTGVPYKIVILQIGESGQIVSNTTYTLVS SNLVNPNEQPILPDGFKFTNDSNIINLPISLDLNSDLDQVVGKYISFVTLLLIFVLVM VKIYASRKKTSSS" gene complement(699..1268) /gene="" /locus_tag="" /db_xref="2663126..2663695" CDS complement(699..1268) /gene="" /product="hypothetical protein" /translation="MLFQKFSIIQMINKTFNNGTVLVGISIISWNTSMQSKFSYSLVN STLPLPFYYVSPLLLGEKNISVSRVNLFYVNHTNSCYVYLGKSNVEGVAIETYFYFKS DGLADKIINLQIGANGKISSETTLVLWMTNFNNTHIGIPYFEGITTASSEVIVSLFPQ YSKIMEYIIIVGALLVMVILLFRGTKWVR" gene 1292..1402 /gene="" /locus_tag="" /db_xref="2663719..2663829" gene complement(1439..1864) /gene="" /locus_tag="" /db_xref="2663866..2664291" CDS complement(1439..1864) /gene="" /product="hypothetical protein" /translation="MIIRRKNAKALSGAVTALILVIASVIIALVVVGFAFGLFGAFAG QGTVTQVGTATLSASNRTLTVTLKNTGATTQVTGVIINGNSATVSGQVTISAGQNTYS ISLVGISSTTLQNLVGSTISLTLQLSNGQTVTVSAIITS" gene complement(2153..2677) /gene="" /locus_tag="" /db_xref="2664580..2665104" CDS complement(2153..2677) /gene="" /product="Insertion element protein" /translation="MGRKAVVRQDVSCPSCGSHHVVKCGRPLGRQRYLCRDCGRYFLG DATYHHHSKKLREEALRLYANGMSIRAISRVLNVPLGTVFSWIKRYGRQKYEKLVELW GKAKDLVKGGVVSKVVDEMWTYLYKNTRAFYKWIFTCYVYTRLEFTSFTLWAIGMRIL FARLKSICWMRVDG" gene 2993..4042 /gene="" /locus_tag="" /db_xref="2665420..2666469" CDS 2993..4042 /gene="" /product="transposase IS4 family protein" /translation="MVTPGLPHQNNIQQIGYKLLSMLNFKGKKGEEVARTLISACLWN DSVESKSRAYGVSPQTVRNYVEEQGVEVIEKLLESARKISLKVLKGVKEIDVSIDWTT KTWYGRPVGGLGSSEEGNSWNYATATTKFNGKVLLLAFVTQVKGMTKEEIVKALVEQV VAMGFKIRLITLDAGFYTVDVLNFISQFKYIVAVPVGDVKVYEEFDGDYTTNSKRHRR DEQVEFRLLVYSKEKVRRKSLVYFARATNLDLSKREVLDLYNKVRGPIETSYRNIKAF LPFTSSTKFVFRTLIFVLALVLYSLYTIFKGEVGREEFRLLLILLFPDLFNPENFTFN IIKTLIYTIDLFLRR" gene 4039..5073 /gene="" /locus_tag="" /db_xref="2666466..2667500" CDS 4039..5073 /gene="" /product="transposase IS116/IS110/IS902 family protein" /translation="VILGLPRRTEHYDKIHACRCDKGVGVIGIDVSKDYLITSRGRVR KYKNNKEGYEEILEMKPCTIVLEPTGVYAIRPSQYFKEKGIKVLQVSPNMLSREKEFR GKKTDFYDAEKLENMVDKAKEYEYNPLREMVTLYLFLKDIEVKYKNRLERTLFLVSDN NKISKERLEKLAKGDFTQEELYQLEYTPIVVEEIKVLAKTLLETQEKLKEVRRMIEEQ VPDNHVLLTIPGIGRLAAGIIIGIVGDVKRFPKPESFVAYCGLDPVVERSGKAVISKG ISKRGNKYLCSLLYFLAGRNYSRNPNLLKFYESHKDRLKGKKFYTALARKLARIIWSV WYNNKPYEPK" gene complement(5058..5303) /gene="" /locus_tag="" /db_xref="2667485..2667730" CDS complement(5058..5303) /gene="" /product="hypothetical protein" /translation="LNFKNKRVLETSYFKDTFIQGEITGTTIFSDKNYLIKRVSVAFS NKYFGHISSIILAKIATWVLSTQVAIKGKGFFNYLGS" gene 5313..6152 /gene="" /locus_tag="" /db_xref="2667740..2668579" CDS 5313..6152 /gene="" /product="hypothetical protein" /translation="MEIEIKTPSATVKINNDNKQTEIINGRDRIVIGRVYYYLTKTIF LIPRLYGITAKEPLVNWKNEFERQFTHILTNELSLAKLLTLELYFKITSPKMSIIGTI QNGKVEAKVELKVLPELELQEDKIRSLVKIDSFYFSDINKKRPYIIPAIRAGLVASFY KFLPIRFEGAPGIPKTLGIISDFINSMVLPQGYSEEVLAHKIYIKDDEVYCDDNILYN ADSSVLSLFPIVYFIKNSSNNDIIVIEQPEVHLEEFKETLKELLKMSKAKLVLVSNEA IST" gene complement(6448..6663) /gene="" /locus_tag="" /db_xref="2668875..2669090" CDS complement(6448..6663) /gene="" /product="transposase ISC1058" /translation="LGYNRWREEKGYGVGWRIESLFSAVKRTFGESVRATSFLGQVVE AKLKFWAYAWMIHLANSLVGRAPGIRV" gene 6743..7162 /gene="" /locus_tag="" /db_xref="2669170..2669589" CDS 6743..7162 /gene="" /product="hypothetical protein" /translation="MIIRRKNAKALSGAVTALILVIASVIIALVVVGFAFGLFGAFAG QGTVTQVGTATLSAGTGTLTVTLKNTGATTQVTGVIINGNPVSLSSQVTISAGQNTYS ISLGTSSTLQNLVGSTISLTLQLSNGQTVTVSAIITS" gene 7278..7643 /gene="" /locus_tag="" /db_xref="2669705..2670070" CDS 7278..7643 /gene="" /product="hypothetical protein" /translation="VEYPYFDLKTARELLPWLRDRLIQLRKIKNEIEILLVNGDKYAL QQYASETKKIIDEIISKGIILRDIDIGLVDFPAIINNKPAFLCWKIDEGDIKYWHYTD EGFRGRKRLTGYEDILSLR" gene 7676..9865 /gene="" /locus_tag="" /db_xref="2670103..2672292" CDS 7676..9865 /gene="" /product="molybdopterin binding aldehyde oxidase and xanthine dehydrogenase" /translation="MYVGERVKRKEDLKFITGSGRYVDDIEYPGTLYLYIVRSNIAHA KIKKIDVSDALKVNGVIGVITGLTIPFENRPRNWPMAKDEILYVGHPIAAILATDKYT AADGADSVQIDYEELPAVIDPEKALKDNVKAVEGKSNIAYKKVYNAGDPDKALSNSDI ILEEKLEISRVYPSPMETRGLLSVYQEGSLLVYASTQSAHYMRRYLLSAFGNMVRDIR VIQADVGGAFGAKLFPYAEDFITVYASLQYKRPVKWVALRSEDIRGMYHGRGQIHKVK FGAKKDGTLTAMIDDAVIDLGAASHGTYLVDIAATMLTGPYKVRDLRVNAYGVYTNKT PLDQYRGAGRPEAAFVYERIMDIISDELKLDPIYVRKRNLITELPYVNPLGLKYDSGN YLKLLEKAEKVYREFEERANELRKQGRRIGAGLSFYLEQNNFGPWESASVRIKADGKV QVIIGASPHGQGTETGIAQIVADELEISVDDVEVIWGDTAIIGEGFGTYGSRSLTLAG NAALLAARTVKEKALRLAAQFMKSDVQELEYKNGEVINPKSGRTMSLKEIATRNMASL GGIWEYKEEPGLEASGYFGFDNLTYPYGSHVVLTEVDDSGKVKILDYYAIDDIGTVVN PMLAEAQVIGGVIQGFGESIFEEIVYDENGNLLTGNLFDYAIPTAVEAFNIKWEYMEE GKSNAPLPAKGIGEGATIGTPPALIRAIEKAIGKRLTRLPSKLENLI" gene 9958..10365 /gene="" /locus_tag="" /db_xref="2672385..2672792" CDS 9958..10365 /gene="" /product="Rhodanese domain-containing protein" /translation="MTQVIESYSSPFYKNIIDLPPSMVRKLWKSGKIIILDIRTPQEY EDHHIPGAILAPLDYLEHLTELFEDREVAVVCEHGNRASYATYGMPHLYKKKAYYMIG GMALWMAMGYEVESGMDENGVLWQKILEMKFNY" gene complement(10355..10753) /gene="" /locus_tag="" /db_xref="2672782..2673180" CDS complement(10355..10753) /gene="" /product="hypothetical protein" /translation="MRKGLSDSLTMMIVILASVILAITVISILFGYLGYFGSSYGEVR QIGTALITQDGKLNITLENSFSNAKIVGIIYSTTLHNIDYTLSIGQHKYTINTGFTFP NGLQTVTLTLVIVTNQNTIYVPVEAQLVNS" gene 11059..13410 /gene="" /locus_tag="" /db_xref="2673486..2675837" CDS 11059..13410 /gene="" /product="Peptidase M1 membrane alanine aminopeptidase" /translation="MIKVNRYEIFLDFSFQTGDYKGYEKIEMESDEETVVLDAVGLKI LKVKVNEKEIEFSQDESKVNVKSGSFSGILEVEFEGKVAERKLVGIYKASYKDGYVIS TQFEATHARDFIPCFDHPAMKAKFKLTVRVDKGLKVISNMPVVREKEENGKLVYEFDE TPRMSTYLLYLGIGNFEEIKDEGKIPTIIVATIPGKVQKGRFSMQISRNSIEFYGKYF EIPYQLPKVHLIAIPEFAYGAMENWGAITFRETALLADDSSSVYQKFRVAEVVAHELA HQWFGNLVTLKWWDDLWLNESFATFMSHKAISQLFPSWNFWGYFVLNQTSKALEKDSV STTHPIEAHVKDPNEVEQMFDDISYGKGASILRMIEAYVGEENFRRGVVNYLKKFSYS NAQGSDLWNSISEVYGSNISPIMADWITKPGYPMVRVSVSGNRVNLEQERFSVLGNVE NLTYKIPLTMEVNGKIVTHLLDKERETITFEEDIKSFKANVNRTGFYRVLYNSYLVFN AKLSELDKWGIINDYWAFLLAGKIDFKEYERIISKFFNDKDFLPVNELSNELFTLYAI NPDKYQGISKEFHRIQLKNWRNSKDELGRLTYSNILYRLAAMDDEFSLGLSEMFRFYD SLDSDTRQGVAVAYAITYEEDAIDELLERYRKESFDEEKLRYLTSMLFFRKPYLVGNT LSLILSGEIKKQDIPYTLSVVSYNPYAKSAVLSWIKMHVNFMREAYKGTGILGRRLAE VIPLIGIGAEKETEQFFSNLKMPEGERGIRTGLELLKAYSRLK" gene 13460..13810 /gene="" /locus_tag="" /db_xref="2675887..2676237" CDS 13460..13810 /gene="" /product="hypothetical protein" /translation="MDKYKLALLGEAGAAGLDRGFSIRYKVFYESYLNEVSHWKYFQK YSRSFLEKPVYYAFSILGFVISLFGIEAVKKVNEIVERNAIDFYKINFNESNEDIKRI LEDEEKHFSMSVDA" gene 13839..14669 /gene="" /locus_tag="" /db_xref="2676266..2677096" CDS 13839..14669 /gene="" /product="xylose isomerase domain-containing protein" /translation="MVKIYLGPAGIPHSSKKKNTIEGIRTVKELGLNAMEVEFVQGVR MSRETAEETGQVAKELGVRLSVHAPYFINLCSEEKDKIDASKQRILDTADRAELMGAD AIAIHIAFYGKMNPEECYQNVKEGLAEVIDKAKEMGIKNVKFGVETMAKETAFGTLDE VISISKELKGVIPYIDWAHTFARQGGEIDYGKIIDRLIKELGLTHINSHFESLVSRKG KYVDEHIPIDANAPPFEPLAKELLKRDISITLICESPELERDALKMKEVLERLGYRLE" gene 14650..15351 /gene="" /locus_tag="" /db_xref="2677077..2677778" CDS 14650..15351 /gene="" /product="SPP-like hydrolase" /translation="LDIDWNEILVASDYDRTLANEESNFVISPIVVQKINEFSKKYKF VVVSGREKKFMDKLAVGLRPTAWILENGSLIFFDNKEFVLCEKSWFERDREKIIEILD NLKAKYSIGRVIIYIDGYGSKLDMLRDIEKYGRIEVNRNDAMILPKGVDKGVGVLKFK ELTGFKGKIIAVGDSENDYALFRIADIKVAVANAIPQIKEIADIVTEKPNGLGVVEIL DKILSGNFGKEVDIH" gene complement(15313..15696) /gene="" /locus_tag="" /db_xref="2677740..2678123" CDS complement(15313..15696) /gene="" /product="hypothetical protein" /translation="VEIDLESLETARNIKSELNLDIELLNADIIQFYGRFDTVIQNPP FGVVNRGIDIKFLQTAFSISNVVYSIHKSNERSRQIIIKIAKEHGFSAEILSERYRLK PYYPWHMKRIHEFLVDIYFFSKIPR" gene complement(15891..16559) /gene="" /locus_tag="" /db_xref="2678318..2678986" CDS complement(15891..16559) /gene="" /product="HAD-superfamily hydrolase" /translation="MKAIFVDLGETLVHFKPRYHENIAYALKEIGYNVDEKRVFKAVA KILGKHHYPSPEYGGLSAFDFRELFYELNIYPDQESIARLNSKNLLSGEYELYDDSIT FLEEAKQLGFKVVLVSNATRNIYKIVEDLGIKKYFDGIVASCDLNVMKPHPKIFSYAM EIAKSDGIHIGDIYEIDVIGAKRAGLEAILLDRLGFYPEIKENRVNNLLEALELVKER LKNS" gene complement(16573..16878) /gene="" /locus_tag="" /db_xref="2679000..2679305" CDS complement(16573..16878) /gene="" /product="hypothetical protein" /translation="LNTDFLTTREKIFFLLSYSDEPLSAREIMRRLDIRKEKEIYDHI EHLARSSKRKGYTLIIIPARCKSCGYAFNSEKIKRPSRCPVCKSEKIEMPKFLIRNK" gene complement(16853..17620) /gene="" /locus_tag="" /db_xref="2679280..2680047" CDS complement(16853..17620) /gene="" /product="dTDP-4-dehydrorhamnose reductase" /translation="LKIAVTDEGEIAKAFARFLGSNSNEITIVDSPSKVIREKPDVIL HTFEIPIFESNMNPPLAWSFNTWYAINIARAGSKVGSVNVFLSSFLIYDGKRGFYKEH NTPNPLNYYGLTKLVGESSIITLGNYLVLRVGALFSLSYRGFLFPFIKASTRGKILKC NKNFYISIIDLNTLAKVSKLLINKEARGVINVGSNRVSLFEICSYLSDIFGNEVIEID NQQRDFSLDDWLLRAYNIKIDAKESILSLIEYRLLNN" ORIGIN 1 tcaactactt gaagtcttct ttctcgacgc ataaattttc accatcacga gtacaaaaat 61 gagcaaaaga gttacaaaac ttatatattt accaactact tgatctagat cagagtttaa 121 atctaaagaa ataggtaaat taataatatt actatcattt gtgaatttaa agccatctgg 181 aagtattggt tgttcgttag gatttacaag atttgagctc actaaagtat aagttgtatt 241 actgactatc tgtccactct cccctatttg aaggataacg atcttatatg gaaccccagt 301 ggaattaacg taataaaaat actcaagctc aatataacct ataaaagtct tgccgtaata 361 tacatagttg gaattatttg aggatagtaa agacaagata acacctcttt caattactgg 421 ttctccaaca ttaggaatat agaaaaaagt ttccggaaga gagacattat ctagaattgt 481 ggaagaagtt agaatctgag agaaattgag aacataaaca gtcagattat aagcgaaggt 541 tgcattatta taacaaactc ttgtaacatt ttcaaaaaga agctctgata gatggtaaac 601 ttggttgtca taatttattt gaatatgaag cgagtactct acaaaggcgt taggaaataa 661 ggctattatt aggagaaata gaagaggaga agacatgact atcttaccca tttagtcccc 721 ctaaataaaa gaattaccat aacgagaagt gccccaacta ttataatgta ctccataatt 781 ttagaatatt gcgggaatag actgacaatt acttcactac ttgcagtcgt aattccctca 841 aagtaaggta ttccaatatg cgtattattg aagttcgtca tccataaaac taatgtagtt 901 tcactagata tcttaccatt tgcacctatc tgtaagttaa ttatcttatc cgccaaacca 961 tcagacttaa aataaaagta agtttctata gctacgcctt ctacattact ttttccgaga 1021 taaacgtaac aggagttagt atgattaaca taaaaaaggt ttactctact tacacttatg 1081 tttttttctc ctaataataa gggtgaaaca taataaaatg gtaatggaag agtagagtta 1141 actaatgaat atgaaaactt actttgcatt gatgtattcc atgatattat acttatacca 1201 actagaactg tcccgttgtt aaaggtcttg tttatcattt gaattataga aaatttctga 1261 aataacatag atccatcttg gagataataa gttgaggtgc cgttataaat tgcgaatgtg 1321 ccagaaacta gagaagattg agaggacgtt attaaagtta aggaaagggc taatggaaaa 1381 agaagaatag acaggaaaaa tattaaaaaa aacttttcat cttgctggct cctctttttc 1441 agctcgttat tattgcactc actgttactg tttgtccatt agaaagttgt aatgtcagcg 1501 aaatagtaga accaactaga ttttgtaatg tagtagaact gatgccaact agtgagattg 1561 aatatgtatt ttgaccagca cttatggtaa cttggcctga tacagtagct gagtttccat 1621 ttataatcac tccagtaact tgtgtagttg ctccagtatt cttcagagtg actgtcagag 1681 ttctattact agcacttagt gttgctgttc cgacttgtgt tactgtccct tgtcctgcaa 1741 atgctccaaa taatccaaag gcaaatccca caactactaa tgctattatt actgatgcta 1801 ttactaatat taatgcagtt acagcaccgg acaatgcttt cgcgttcttt ctcctaataa 1861 tcatgttcat acctaatata atctaactaa tagttctata taaatgtttc ttccaaagtg 1921 cttgagtgtg acatagggtc gtcattaagc tacaaattct ggtattagct ttttctccca 1981 taagactagg gctatgaagt acatcatggt actaatgctc ctatttactg ccttagtagc 2041 cctcttaaaa cgtacaagct atcccttagt gaggaatgaa aggactcgtt cgggttaact 2101 ggtgagataa ccgtgtggtc tttcaaccag aagtacaagt tataatcatc gctcacccat 2161 ctaccctcat ccaacaaata ctttttaacc ttgcgaaaag tattctcatc cctatcgccc 2221 acagagtaaa tgaggtaaac tccaatctcg tgtacacata acaagtaaaa atccatttat 2281 agaatgccct agtattcttg tacaagtaag tccacatctc atcaacaacc ttactcacaa 2341 caccaccctt aaccaaatcc ttagccttcc cccacaactc aacaagcttc tcgtacttct 2401 gcctaccata acgcttaatc caagagaaca cagtacctag aggtacgtta agcaccctgg 2461 atatggccct tatactcata ccattagcat acaacctcaa agcctcctcc ctcaacttct 2521 tggaatggtg atggtaagta gcgtcaccca agaagtatct accacaatcc ctacacaaat 2581 acctctgcct acccaaaggc ctaccgcact taacaacatg atgagaacca caagaggggc 2641 aagaaacgtc ttgcctaact acagccttcc tacccataag taatactcgt tatacaaata 2701 taaatagctt aatgactaca ctatgtccta tataggtttt attagtcggg gagagtaata 2761 ctctcctcgg ctggggaaac atggtcgaga cactatctga agcaaagtct tcgggtgagg 2821 gcgtgaccaa cccctaccgt ccggtagacc caaaatcata ttaggaaaaa tatttctgat 2881 aggataatat cgaacttata aaagataaag aaatttataa gagtataaag aattcaattg 2941 aagaaagggt ttaaggtgag ggagatggag tattaccacg tgagatagga agatggtaac 3001 acccggtctc cctcaccaaa ataacattca acaaatagga tataaattac tttccatgct 3061 gaacttcaag ggaaagaaag gggaagaggt ggcgagaacc ctcatctcag cgtgtttatg 3121 gaacgattcg gtggaaagca agtccagagc gtatggcgtg tccccacaga ccgtgaggaa 3181 ttacgtggag gagcaagggg tggaagttat tgagaaactc ttggaaagcg ccaggaagat 3241 atccttgaag gtactgaagg gagtcaagga gatagacgtc tcaatagact ggacaaccaa 3301 gacctggtac gggagaccgg tgggagggct cgggagttcg gaggagggaa actcttggaa 3361 ctacgcaact gcgacgacaa agtttaatgg gaaagtgctc ctactggcct tcgtcactca 3421 agtcaagggg atgactaagg aagagatcgt gaaggccctc gtggagcaag tcgtcgcgat 3481 ggggttcaag ataaggttga taactcttga cgctggtttc tacacagttg atgtgctcaa 3541 tttcatttca cagtttaagt atatagttgc tgtcccagtt ggggatgtta aggtgtatga 3601 ggagtttgac ggggattaca caactaatag taagaggcat aggagggatg agcaggtcga 3661 gttcaggctt ctcgtgtaca gcaaggaaaa agtgaggaga aagagtcttg tttattttgc 3721 tagggctact aacctagacc tatccaagag ggaagtgttg gatttgtata ataaggtaag 3781 gggtcccata gagacctctt ataggaacat taaggctttt cttccattta ctagttctac 3841 taagtttgtt tttcgcacgt tgatcttcgt gctggccctt gtactctact ccttatatac 3901 catattcaag ggggaggtgg ggagagagga gtttagatta ttattaattc ttttatttcc 3961 tgatttattc aatccagaga attttacatt taatataatt aaaacactta tttacactat 4021 agatttattt ttaaggaggt gattttgggt ctaccgcgtc ggactgaaca ttatgataaa 4081 attcacgcat gtaggtgtga caaaggggta ggggtaatag gaatagacgt atcaaaagat 4141 tatttaataa ctagtagggg gagggtgaga aaatacaaga acaacaaaga gggatatgaa 4201 gagatacttg aaatgaaacc ttgtacaata gtcctagaac ctacgggagt ttacgcaata 4261 aggccttcac aatacttcaa ggagaaagga ataaaagtac tacaagtaag cccaaacatg 4321 ttatcaagag aaaaggagtt taggggaaag aaaacggatt tttacgatgc tgaaaaatta 4381 gaaaacatgg ttgataaggc aaaggagtac gagtataacc ccttgaggga aatggtaaca 4441 ctttacctct tcctcaagga catagaagta aagtacaaga acaggttaga gagaacacta 4501 ttcctagtaa gcgacaacaa caagataagc aaggaaaggt tagaaaaact cgcaaaagga 4561 gattttacac aagaagaact ataccaacta gaatacacac caatagtagt tgaagaaatc 4621 aaagtcctag caaaaacact cctagaaacg caagagaaat tgaaagaagt taggaggatg 4681 atcgaggaac aagtaccgga taatcacgtt ttattaacaa tcccgggaat tgggaggctt 4741 gcagctggta ttattattgg tattgttggt gatgttaagc gttttcctaa accagagtcc 4801 tttgtggctt attgtggtct cgatccagtt gtggaaagga gtggaaaagc tgtaataagt 4861 aagggtattt cgaagagggg taataagtac ttgtgtagtt tgctttactt cttggcaggg 4921 aggaattatt ctaggaatcc taatttgctg aagttttatg agtctcataa ggataggtta 4981 aaaggtaaga agttctacac tgctttggct aggaagttgg caaggattat atggagtgta 5041 tggtataata ataagcctta tgagcccaaa taattaaaga aacccttccc cttaatcgcc 5101 acctgggttg aaaggaccca cgtggcaatc ttagctaata ttatgcttga aatatgaccg 5161 aaatatttat tactgaacgc cacactcact ctttttatga gatagttttt atcactaaaa 5221 attgtagtac cagttatctc gccttgtata aatgtgtctt taaaataaga agtttctaaa 5281 actcttttat ttttaaaatt caaataacgc ttatggaaat agagataaaa actccttctg 5341 ctactgttaa aattaataat gataataagc aaactgaaat aattaacgga agggatagaa 5401 ttgtaatagg tagagtttac tactatctaa ctaagaccat attcttaatt cctagacttt 5461 atggaataac agctaaagaa ccactcgtaa attggaaaaa cgagtttgaa agacaattca 5521 cgcatatttt aacaaatgag ttaagtttag ctaagttatt aacattagaa ttatacttta 5581 aaataacctc acctaaaatg tctatcatag ggactattca aaatggtaag gttgaagcta 5641 aagtagagtt gaaagtttta cctgagttag aactgcaaga agataagatt aggagtttgg 5701 ttaagataga ctccttttac ttttcagata ttaataagaa gagaccatac attataccag 5761 caattagggc tggattggta gcatcatttt acaaatttct tcccattagg tttgagggag 5821 ctccgggtat tccaaagacg ctcggcataa tttctgattt cataaactca atggtcttac 5881 cacaagggta ttctgaagag gttctagcac ataaaatcta cattaaagac gatgaagttt 5941 actgtgatga taatatacta tataatgcgg actcttccgt gttaagctta tttcctatag 6001 tctatttcat taaaaattca agcaataatg atattatagt tatagagcaa cctgaagttc 6061 atctagagga gtttaaagaa actctaaaag agttacttaa aatgtctaag gcaaaattag 6121 tattggttag taatgaagca atctcgactt gaatataaat taaagaggct atatcttttg 6181 tttatatagg aaattagcaa attatattct agagatgtat tctgacttat cgggaattca 6241 gaaaacaaat ccacttaaga atattaatca aaatataaat agcctccatg gtatttaatg 6301 tcctattagg gcgccgtgag aagaccctac caagatgtat gtgtagttgg aatgctttgt 6361 tgatctcttc aatttatttc ataagcatga aatgatacac tgagaatttt tcagtaatta 6421 atatttattt caacgttatt cgcaagctca caccctaata cccggagctc taccaactaa 6481 agaattagcc aagtggatca tccacgcgta agcccagaac ttgagcttag cctcaaccac 6541 ttgccctaaa aaacttgtag ccctaacaga ttccccaaaa gtacgcttca cagcagagaa 6601 taaggactca atcctccacc caacaccata acccttctcc tccctccaac gattataacc 6661 caacttcttg aactccctta cagcctttag ttggaagaaa catttatata gaactattag 6721 ttagattata ttaggtatga acatgattat taggagaaag aacgcgaaag cattgtccgg 6781 tgctgtaact gcattaatat tagtaatagc atcagtaata atagcattag tagttgtggg 6841 atttgccttt ggattatttg gagcatttgc aggacaaggg acagtaacac aagtcggaac 6901 agcaacacta agtgctggta ctggaactct gacagtcact ctgaagaata ctggagcaac 6961 tacacaagtt actggagtga ttataaatgg aaacccagtt agtttatcaa gccaagttac 7021 cataagtgct ggtcaaaata catattcaat ctcactaggc accagttcta cattacaaaa 7081 tctagttggt tctactattt cgctgacatt acaactttct aatggacaaa cagtaacagt 7141 gagtgcaata ataacgagct gaaaaagagg agccagcaag atgaaaagtt ttttttaata 7201 tttttccaat tttgcaaaaa tttttatcat aattcatata aacattatta tttaagcctt 7261 tgcgaatact agtatttgtg gaatacccat attttgactt gaagactgct agagaattgt 7321 taccgtggct tagggatcgc ttaatacaat tgagaaagat aaagaatgag attgagatcc 7381 ttttagttaa tggtgataaa tatgctttgc aacaatacgc tagtgagact aagaaaatta 7441 ttgacgaaat catttcaaag ggtattatac tacgagacat agatataggc ttagttgact 7501 tcccagctat tataaataat aagcctgcat ttctttgttg gaaaatagac gagggtgaca 7561 taaagtattg gcactatacg gacgagggat ttagagggag aaagaggtta actggttatg 7621 aggatattct aagtttacgt taaatttatt tatttaattc tcttaacaat tccctatgta 7681 cgttggtgaa agagtaaaaa gaaaagagga tttaaagttc attactggtt ctggacgata 7741 cgttgacgac attgagtacc cggggacatt atacctttat attgttagga gtaacattgc 7801 gcacgctaaa attaagaaga ttgacgttag tgacgctttg aaagtaaatg gtgttattgg 7861 tgttatcact ggtttgacaa tcccttttga gaatagacct aggaattggc caatggccaa 7921 ggatgagata ttatacgttg gccatcctat tgcagcaatt ttggctactg ataaatatac 7981 agcagctgat ggtgcagatt cggttcaaat agactacgag gagttacctg cagttatcga 8041 tccagaaaag gctttgaaag acaatgtaaa agcagttgag ggtaaaagta atattgccta 8101 taagaaggtt tataacgcgg gtgatccaga taaagccctt tcaaactcag atattatatt 8161 ggaggagaaa ctcgaaattt caagggttta tccctcgcca atggaaacta gaggattgct 8221 ttcagtatat caagagggta gtttgttagt ttacgcatct actcaatccg cccattacat 8281 gagaaggtat ttattgtcag cctttggtaa catggttagg gatataagag ttattcaagc 8341 tgatgttgga ggtgcttttg gggctaagtt attcccatat gctgaggatt tcataactgt 8401 ttacgctagt ttgcaataca agaggcccgt aaagtgggtt gctttaagga gtgaggatat 8461 aaggggtatg taccatggta ggggacagat acacaaggtt aagtttggag ctaaaaagga 8521 tggtactttg actgcaatga tagacgatgc ggttattgac ttaggtgctg cttctcatgg 8581 aacttacttg gtggatatag cagctacaat gttgactgga ccgtataagg ttagggatct 8641 aagggttaat gcttatggcg tttacacgaa taagactccg ttggatcaat ataggggtgc 8701 cggtaggcca gaggctgctt tcgtatacga aaggatcatg gatattattt ctgatgagct 8761 gaaattggat ccaatttacg ttagaaaaag gaacttaatt actgaattac cttatgttaa 8821 tcctcttggt ctaaagtatg attctggtaa ttacttaaag ttactggaaa aagccgagaa 8881 agtctatagg gagtttgagg agagagctaa tgagttgaga aaacaaggta gaagaattgg 8941 tgctggttta tcattttatc tagagcagaa taactttggt ccttgggaga gcgcttcagt 9001 taggattaag gcggatggta aggttcaagt tataattggt gcaagtccac atggccaagg 9061 tactgaaact ggtattgctc aaatcgttgc cgatgaatta gaaataagtg ttgatgatgt 9121 tgaagtgatc tggggcgata ccgctattat aggtgagggt tttggtactt acggtagtag 9181 gagtttaacc ttagctggta atgcagcatt attagctgct aggacggtaa aggagaaggc 9241 tttgaggtta gctgcacaat ttatgaagtc agatgttcaa gagcttgaat ataagaacgg 9301 tgaggttatt aatcctaaga gtggtagaac aatgagtctg aaggaaattg ctactcgtaa 9361 tatggctagc ttaggtggta tttgggagta caaggaagaa cccggactgg aagctagtgg 9421 atatttcgga tttgataatc taacttatcc ctacggttca catgtggttt taacagaggt 9481 tgatgattct ggaaaggtta agatactaga ttattatgct attgacgata taggtactgt 9541 tgtaaatcca atgttagctg aagctcaagt tataggagga gtgattcaag gctttggtga 9601 aagtattttt gaggaaattg tttacgacga gaatggtaat ttgctaactg gtaatttgtt 9661 tgattacgct attccaacag ctgttgaggc attcaatatt aaatgggagt acatggaaga 9721 gggaaagtct aatgctcctt tgccagcaaa gggaattggt gagggagcga caatcggtac 9781 tccaccggct cttataaggg caatagagaa ggctattggt aagaggttaa ctagattgcc 9841 aagcaaatta gagaatttaa tataaaattc tcctttttta taaagtaatt taaaattctt 9901 ttgacagtag tatagataga aagctattta agtaaaaata aacactgtta aagcagtatg 9961 actcaagtaa tagaatccta ttcctcacca ttttataaga acataatcga tttacctcca 10021 tcaatggtta ggaaattatg gaaaagtgga aagataataa tactcgatat tagaacacca 10081 caggaatatg aggaccatca cataccgggg gcgatcttag cacccctaga ctatctagaa 10141 catttaactg aacttttcga agatagggaa gttgcagtag tttgtgaaca cggaaatagg 10201 gctagttatg ccacatacgg tatgcctcat ctttacaaga aaaaggctta ctatatgatt 10261 ggtggaatgg cattatggat ggcaatgggt tacgaagtgg aaagtggaat ggacgaaaat 10321 ggagtgttat ggcaaaagat tctagaaatg aaattcaact attaacaagc tgagcctcca 10381 ctggaacgta aatagtattt tggttagtta ctattactag agtcaaagtt actgtttgta 10441 acccattagg aaaggtaaat ccagtgttaa tagtatattt atgttggcct atcgatagcg 10501 tatagtcaat gttatgcaaa gttgtgctgt agattatccc tactatctta gcattgctaa 10561 aggaattttc caaggtgatg ttgagtttac catcttgtgt tatgagagct gtacctattt 10621 gtcttacttc tccatagctg cttccaaaat accccagata tccgaacaat atagaaatta 10681 ctgttatagc taagattact gaggctagta tcactatcat cattgtcaag gaatcactta 10741 aaccttttct catatgtgtt atttagtttt cgatgaatat aaattagacc gttttatata 10801 gattttttgt actgattttt atatatagtt atacgagtct agtgaaaaag gtttatatag 10861 aatagatatc gctgatattc tgctacaatg aagaatacga aacaccaggt cctttagggt 10921 atagcaaata ccgaacttta atcaaaacta agaggttcat atatgttaag agtcctctga 10981 tcctcctaaa aatacccttg ataacgagtt ttcaagttaa tagaaaacac tttaaacctt 11041 attatatcat aaaaacacat gattaaggtt aatagatacg agatttttct tgatttcagc 11101 tttcaaactg gagattataa gggatatgag aaaattgaaa tggaaagcga tgaagaaaca 11161 gtagtactag acgctgtagg tttgaagatt ttaaaagtaa aagtaaacga aaaagagatt 11221 gaattctcac aagacgagag taaagtcaac gtgaaaagtg gatctttttc tggtatttta 11281 gaggtagaat ttgagggaaa ggttgctgaa aggaaattgg tgggtattta taaggcttct 11341 tataaagatg gatacgttat tagtacgcag tttgaggcaa cacatgctag ggactttatc 11401 ccttgttttg atcatcctgc aatgaaggcc aagtttaagt taactgttag agttgataaa 11461 gggcttaagg taatatccaa tatgccagta gtaagagaaa aggaagagaa tgggaaatta 11521 gtatatgaat ttgatgaaac gcctagaatg tctacctatt tactatacct aggaattgga 11581 aactttgagg aaattaaaga tgaaggtaag attccaacaa ttatagtagc cacaatacca 11641 ggcaaagtgc aaaagggaag attctctatg cagatctcaa gaaattctat agagttctat 11701 gggaagtatt ttgaaattcc ctaccaattg cctaaagttc atttaatcgc aataccggaa 11761 ttcgcatatg gggctatgga gaattggggg gcaattactt ttagggagac tgctttattg 11821 gctgatgatt cttcttctgt ttatcagaag tttagggttg ctgaggttgt tgctcatgag 11881 ttagctcacc aatggtttgg taacttggta actttaaagt ggtgggacga tttatggtta 11941 aacgagagtt tcgcaacatt catgagccat aaggctattt cgcaactatt cccgtcatgg 12001 aacttctggg gttatttcgt tttaaaccag acttctaaag cattggagaa ggactctgtg 12061 tcaactacgc acccaataga ggcacacgta aaggacccta atgaagtaga gcaaatgttt 12121 gatgatatta gttacggtaa gggggctagt attttaagga tgattgaggc ttatgttggt 12181 gaggagaatt tcagaagggg tgtagttaac tacttaaaga agttctcgta ttcaaacgct 12241 caaggttctg atttatggaa ttccatttct gaagtttatg gttctaatat ttctccgata 12301 atggctgact ggataactaa acctggctat cccatggtta gggttagtgt ttctggaaat 12361 cgcgtaaact tagagcagga gagattttcg gtattaggaa acgttgagaa cttgacttat 12421 aagattcctc ttaccatgga ggttaacggt aagattgtaa ctcatttact agacaaggag 12481 agagagacta taacttttga ggaagatata aagagcttta aggctaacgt aaataggact 12541 ggattttatc gagttcttta caactcttat ctagtgttca atgccaaatt atcagagctc 12601 gacaagtggg gtattataaa cgattactgg gctttcctat tggctggtaa aatagacttt 12661 aaggaatatg aaaggataat atctaaattc tttaatgaca aagatttctt accggttaat 12721 gagctttcta atgaattatt taccctttat gcgataaatc cggacaagta tcaaggtatt 12781 tcaaaggaat ttcatagaat tcagctgaag aattggagaa attcaaagga tgagttagga 12841 agactgacgt attcaaatat tctttataga cttgctgcaa tggatgatga gttctcttta 12901 ggtctttctg agatgttcag attctacgat tctctagatt ctgatacgag acaaggagta 12961 gctgtggcat atgctattac ttatgaagag gacgctattg acgaactgtt agagagatat 13021 aggaaggaaa gctttgatga ggaaaaactt agatatctaa ccagcatgtt attctttagg 13081 aagccttatc ttgtgggaaa cactttaagt ttaatactga gcggtgagat taagaagcaa 13141 gatattcctt atacattaag cgtagtatct tacaaccctt atgctaagag tgcagtgcta 13201 agttggatta agatgcatgt caacttcatg agagaggcct ataaggggac tgggatactt 13261 gggaggagac ttgcagaagt tattccacta attggaatag gggcagaaaa agaaactgag 13321 cagttcttta gtaatcttaa aatgccagaa ggagagagag gaataagaac agggttggag 13381 ttacttaaag cttattcgag gttaaagtga taaagatttt ttaacatgta ccttttaccc 13441 tttctaaata ttatatatca tggataagta caaattagct ttattaggtg aagctggtgc 13501 ggccggatta gatagaggat tttcgattag atataaggtt ttttacgagt cttatctgaa 13561 cgaggtatct cactggaagt attttcaaaa atatagtaga tcgttcttgg agaaacccgt 13621 atattacgct ttttcaatcc ttggttttgt gatttcacta tttggaatag aggctgttaa 13681 aaaggttaat gagatcgtag aaagaaacgc cattgatttt tacaagatta actttaatga 13741 gagtaatgaa gatataaaga gaattctgga ggatgaggaa aagcacttct ctatgtcagt 13801 tgatgcttaa ataagttttg cataagaaga ttaaattaat ggtaaagatt tacttaggtc 13861 ctgcgggaat tccgcactcc tctaaaaaga agaatacgat tgagggtata aggactgtta 13921 aagagttagg cttaaacgct atggaagttg agttcgtgca aggtgtaaga atgagcaggg 13981 aaactgcaga ggaaactgga caagttgcta aggaattggg agttaggtta tcggttcacg 14041 ctccatattt catcaatttg tgttccgagg aaaaagacaa aattgatgct tcgaagcaga 14101 gaattttaga tacagctgac agggctgagt taatgggagc tgatgctata gctattcata 14161 ttgcattcta cggtaaaatg aacccagaag aatgttatca aaacgttaag gaaggattag 14221 cagaggtaat agataaggct aaggaaatgg gtataaagaa cgttaagttt ggtgttgaaa 14281 ctatggctaa ggaaactgct tttgggactt tagatgaagt catctcgata tctaaagagc 14341 taaagggcgt aataccctac atagattggg ctcatacttt tgctaggcaa ggtggggaaa 14401 tagattatgg gaagattatc gataggctaa ttaaggaatt aggtttgact catataaatt 14461 ctcacttcga atctctagtt tctaggaaag gaaaatatgt ggatgagcat attcccatag 14521 atgctaacgc cccaccgttt gaaccattag ctaaggaatt gcttaaaagg gatatttcga 14581 taacattgat atgtgaaagt ccagaattgg aaagagatgc gttaaaaatg aaggaggtat 14641 tggagagact tggatataga ctggaatgaa atactagtag cttcggatta tgataggaca 14701 ttagccaatg aagagagtaa ttttgtaata tcccccattg ttgtacaaaa gataaatgaa 14761 ttttcaaaaa agtataagtt tgttgtagtg agtggtaggg aaaagaaatt tatggacaag 14821 ttggctgttg gtttaagacc tactgcgtgg atactggaga atggttcgtt gatatttttc 14881 gataataaag agtttgtgct ttgtgaaaag agttggtttg aaagagatag ggagaagata 14941 attgaaatat tagataatct taaagctaag tattctatag gtagagttat aatatatatt 15001 gatggttatg gatctaaatt agatatgcta agggatatag aaaagtatgg aagaatagag 15061 gtgaatagaa acgatgctat gattctacct aaaggtgtgg acaagggtgt aggagttttg 15121 aagtttaagg aattaactgg atttaaggga aagataatag ctgtaggaga tagtgaaaac 15181 gattatgcgt tatttagaat tgctgacatt aaagtagcag ttgcaaatgc aatacctcaa 15241 ataaaggaaa ttgctgatat agtgactgaa aaacctaatg gtttaggagt agtggagatt 15301 ttagataaga tattatctgg gaattttgga aaagaagtag atatccacta agaactcatg 15361 aattcttttc atgtgccaag gataatatgg ttttaatctg tacctctcag acaatatttc 15421 agcagaaaat ccgtgctctt tagctatttt gattataatt tgcctcgatc tttcattaga 15481 cttatgtata gagtagacta cattggaaat actaaaagct gtttgtaaaa acttaatatc 15541 tattcctcta tttactactc caaatggagg attttgaatt acagtatcaa atctaccgta 15601 aaattggatt atatcagcat ttaacagctc tatgtctaag tttagttcgc ttttgatatt 15661 tcttgcagtc tctaatgatt ctagatcaat ctccacacaa gtgcaataag cacctaaaag 15721 tgaagccgca aagcagaaaa cgccagttcc acaacctaaa tcaactacct tcttattgct 15781 tatatgccca gatatatatg cgtgccaaac tatttgagca actattggtg aaggtgttac 15841 atactgttct agttcgtact tcggatttgg atgtggtttt gaatattttt ctaggaattt 15901 ttcaatctct cttttactaa ttctagagct tccaataaat tattcaccct attttccttt 15961 atttcaggat agaaccctaa tctatctaaa agtattgcct caagacctgc tcttttcgca 16021 ccaattacgt ctatttcgta aatgtcgcct atatgaatac catcactttt agcgatttcc 16081 atggcgtagg agaaaatctt tgggtgaggt ttcataacgt tcaaatcaca tgatgctact 16141 ataccatcaa agtacttctt aatacccaga tcttctacta ttttatagat atttctggtt 16201 gcgttactaa ctaaaacaac tttaaatccg agttgtttgg cttcctctag gaacgtaatt 16261 gaatcgtcat agagttcata ttccccagat aacaagtttt tgctatttaa tctagctatt 16321 gattcttgat caggatatat attaagttca taaaacagtt ccctaaaatc aaaagctgaa 16381 agacctccgt attctgggct aggatagtga tgttttccta gaatcttcgc aactgccttg 16441 aaaactctct tttcgtcaac attataccca atttccttaa gggcatatgc aatattttcg 16501 tggtatctag gcttaaagtg tactagcgtc tctcctaagt ctacaaatat tgccttcata 16561 tatatattcg ctttacttgt tcctaattaa aaattttggc atttcaattt tctcagactt 16621 gcaaactggg catctactag gcctttttat tttctcagag ttgaatgcgt agccgcaact 16681 cttgcaccta gccggtatta ttataagcgt ataacctttc cttttgctcg accttgccaa 16741 atgctctata tgatcgtaaa tctctttttc cttcctaata tctagtcttc tcattatctc 16801 cctagcactc aacggttcat ctgaataaga taacaagaaa aatatttttt ccctagttgt 16861 taagaagtct gtattcaatt aagctcaata tactctcttt tgcgtcaatt ttaatattat 16921 atgctctcag tagccaatca tctagagaaa aatccctctg ttgattatca atttcaataa 16981 cttcatttcc aaagatatct gaaagataac tacatatttc aaaaagagat actctgttac 17041 ttcctacgtt tattacaccc ctagcctctt tattaataag taatttactt accttagcta 17101 gcgtattcaa atcaataata gatatataaa agtttttatt acatttcaag atttttcccc 17161 ttgtagaagc tttaataaat ggaaatagaa aacccctata tgatagtgaa aataacgctc 17221 caactcttaa aaccaagtaa ttacctaaag tgataatact actttctcca actagtttgg 17281 ttaatccata gtaattcaat ggattaggag tattatgctc tttgtaaaaa cctctctttc 17341 catcataaat tagaaaagaa gaaagaaata catttacgct tcctacctta gaaccagctc 17401 tagctatgtt aatagcatac cacgtgttaa atgaccaagc taagggggga ttcatgttac 17461 tttcaaaaat tggtatttca aaggtgtgca atatcacatc tggtttttct cttataacct 17521 tagaaggact atccactatt gtaatctcat tactattact accaagaaat ctggcaaagg 17581 ctttagcaat ctctccttca tctgtaactg caattttcaa tatctatatc ctctctgatc 17641 tagaattaaa aagtttcgat gattatatag tg //