LOCUS NC_012470:5 18958 bp DNA linear BCT 07-OCT-2011 DEFINITION Streptococcus equi subsp. zooepidemicus, complete genome. ACCESSION NC_012470 SOURCE Streptococcus equi subsp. zooepidemicus, complete genome. COMMENT locus start: 1061392; locus end: 1080349 FEATURES Location/Qualifiers source 1..18958 /organism="Streptococcus equi subsp. zooepidemicus, complete genome." gene complement(0..1571) /gene="" /locus_tag="" /db_xref="1061392..1062963" CDS complement(0..1571) /gene="" /product="signal recognition particle protein" /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMSELREVKALAKPNEI LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEERERPE LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM KRQANKIKKAKKKRK" gene complement(1586..1918) /gene="" /locus_tag="" /db_xref="1062978..1063310" CDS complement(1586..1918) /gene="" /product="DNA-binding protein" /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI LTSIDNRD" gene complement(2151..2849) /gene="" /locus_tag="" /db_xref="1063543..1064241" CDS complement(2151..2849) /gene="" /product="GntR family regulatory protein" /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS QYVGDRFEFYLENN" gene 3123..4685 /gene="" /locus_tag="" /db_xref="1064515..1066077" CDS 3123..4685 /gene="" /product="GMP synthase [glutamine-hydrolyzing]" /translation="MTEISMLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHNI TAQELRDINPIGIVLSGGPNSVYADDAFGIDPEIFELGIPILGICYGMQLITHTLGGK VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK IRKTVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLEGVDFLAQGT LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV VWRQPFPGPGLAIRIMGEITAEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD ITSKPPATVEWE" gene complement(5463..6161) /gene="" /locus_tag="" /db_xref="1066855..1067553" CDS complement(5463..6161) /gene="" /product="phage repressor-like protein" /translation="MLMFSGIQLKTARLSRHISQEQLGELLGVNKMTISNWEKEKNKP NQKHFEELIKIFQLPAEYFYQENRLLLPYSQLSAFNKEKVISYSESLLEQQEKMIALP AKQKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNG EVVLIKQNSFDYDGAIYAVEWEGQTYIKKVYREENGLRLVSLNKKYPDKFAAFDDNPR IIGKIIANFMPLDV" gene 6348..6785 /gene="" /locus_tag="" /db_xref="1067740..1068177" CDS 6348..6785 /gene="" /product="GtrA-like protein" /translation="MLSKQKLSLEIIHYLISGLLTTILYFVLRYVIYSWLHQATISAG FANVIAIIAAFLMNDSYVFKQTSDKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV IGSLVEHDSERINSVESILSQALMVSLNFAISKYYIFKRHRSR" gene 7126..7899 /gene="" /locus_tag="" /db_xref="1068518..1069291" CDS 7126..7899 /gene="" /product="hypothetical protein" /translation="MTEDLNPSIVPRLNPKLLPAATIIKNFVDGEPDCNYEIYLLELL NNSTHFLKKGGSCFSAPSDESHGQCDAISKDYDIDFKLLSSSTRLQASNLFSYGISNL GNGITAITESKKKTGEIKATQIHVAFQTKDVAELIQLKEDFQNSRKHGIEKDIINVLN TLEKKKNIMLFFPYTCELEGYLETENLDDIIVSELNYYFNSLFVYRSLKMKEFDTYFV TIFQERFYIFSIQDDTLNLVEKIDCVLLPAFIKLKNYHL" gene 7913..9418 /gene="" /locus_tag="" /db_xref="1069305..1070810" CDS 7913..9418 /gene="" /product="protein kinase" /translation="LINPDFYKRLATIFCGDEMELFTYKSGPQLVSFFNTHFNAHDSY RQGFPTRWVYVNDKLLDFASKGIINSFFNLILSKQYLLTERQISEVDAIEHQQKIIDE LDKICSVYSLKLSKKGNEFSLVEIDLDLVEIGKGGFADIYFQKSTGLVLKKLNEESIR HQSLRSRLKREYEITKSCSDIGSIIRVFDFDRSNCSYTMEKADCTLVDYIEESELTEE SMFNILRQVIYTISLVHQRDVLHRDISPTNIFFVNGIIKIADFGLGKNLNTLTSHQTM DTASFGQLFYCAPEQLTLLKDADKRSDVYSLGRIINFVMTKNPNIFSHSLRSISEKAT NLEPDYRYQDATEMLNALNSWLNIRSDETFKKTIWEKIDKGVFDNDIENYIYEMSAKD LCQACINKRNIFIDCLLSFMKLDDTHANYIVQTIHSNYEQYLKQFEDADPFATLSYRV LRGNFSFTVNEVAARILKYVAHVVNRFSAKRMIDSLVDEGLEPLIETILER" gene 9420..10100 /gene="" /locus_tag="" /db_xref="1070812..1071492" CDS 9420..10100 /gene="" /product="hypothetical protein" /translation="LRGNVMTNDEYFNEIENYFKKLKYYKEKSKTIVAGIMDENSTEV DMFFISALNRRVQFMDGIIELLKTRNLTCAGILVRTQLDNLMRVFAAFISDDRRKFIQ ASLNGKGIRNMKDNQNKKMTDFYLKKRISEYYPEIEEIYNKSSGYVHLSEVAFHQAFW IDKSDGKDSFRFSVGLSPREELNPVLIECAEVFCHFTEIEYDFYQKIIDSKKIFDQRE KNIDKYNK" gene 10214..10726 /gene="" /locus_tag="" /db_xref="1071606..1072118" CDS 10214..10726 /gene="" /product="hypothetical protein" /translation="MAKYIFPDKTDLVNYLYEVLDNPSPIKIQKTLYLLFAYYGATYG KINLSNDSELDISNYTEFLFEPNFEAWMYGPVDFEVYERNKNGEYSAQKLSFESLNNE LNLSEKQNIVNFSDNIIRQTNVADDFSLVDRTHEDESWSIPYEKGNGAAHIPMDPYQI VEEYSTKYVQ" gene 10716..11381 /gene="" /locus_tag="" /db_xref="1072108..1072773" CDS 10716..11381 /gene="" /product="hypothetical protein" /translation="MFSNLNIGIKTGLKSPVSIKFQNKVFNSETYTPPTNINLKDVKV EVVFMNSAKKFINLPDLKFTNKKADVGEEDPKTLLNLDKLREDQNFLKYNSLPITISS NEQGNRIKGILYNFLEKDFVDQHEFCFRKSAIEDDFDVTNIHNGRFRVICLYRIKPST HKKERRKHYLEIAILDPYHLFIPSKLKVKEESSNKVITLDRDAAMNRVYNSVKDYNKD FDI" gene 11446..12075 /gene="" /locus_tag="" /db_xref="1072838..1073467" CDS 11446..12075 /gene="" /product="hypothetical protein" /translation="MWVEPEDFAWTYAKTNDFDWFKKRLMHWIESRDYDGIPENTKKV LKEVRQSFINQRQNGHRKAELQSEYWDKVIDYLAVAYYEERPGHLFTTSVTALNRPID EFSKDIQRIIWRFAETEDVEGAIKCLVGFVRPYLNEIHLFKLEPVFTDASEKLKKQRS QQIHKEDMDNEYWKIMIYNLDNVFVRLENYKSKTVYFNYLIQAELEKHK" gene 12232..15204 /gene="" /locus_tag="" /db_xref="1073624..1076596" CDS 12232..15204 /gene="" /product="type II restriction enzyme-methylase" /translation="MKNQIKALVNKFTSNKEYYQESTYDETSTRIDFLNKFFEIFGWD VSNNALLPENLREVIHEATIEVEEGNITKKKKPDYQFQIQGKGVFFVEAKKPSVDISV SQKSVFQLRRYGWSAGMQYSILTNFKEISFYDCTIKPNESDDVNVARIAKFNYTEYVE KIEEIAKFLEKNIVEKNEFDLSNSRQFSDFDVYFLNQIKSWRYSLAQNIIEHNEIIDI EDFNVFIQRFINKVLFLRICEDTNLEEYEQLQKIKNIVELQELFANADKKYNSGIFHL LDENIYTVDFEIIKVIFAELYYPLSPYDFSVIPPSILAKVYDVFLSERFEILNDEIKL VKKPEAIDFFGAVTTPKEIADLIVKESFEIRSEKNEIILEEFKIADICCGSGIFLLSA YEYLQNIIYDFSIKRLQQSLDDGVLVKEQNSYQLSFKTKKELLKSAIFGVDIDLSAVE VCKFSLLLSCLRNISFTELAQIKQESLLPNLDNNIKFGNSLVDDKFYDYYSTSNNSDN LLDIVGKISPFDFKEEFGKDIKFDLIVGNPPYTRSQKLAKYSPIEYQYFKSLASNYKS AQISSLDKYHLFVERGLHLLRENSGVLGYIIPNRFIKEKNQNTFRHILFENRCVKKII NYNEIQLFHGVSAYTCLLFLTSDRNHKTEYVSLSLKQSIPVSEQFGLSEFYDTDCLTS EPWELYSKETRQFLKLTSDINKFCKLHDLSDISVGLQTSLDEVFIIEADSSDDDFYYF SKNGIKYKVEKDIVKPAIYRVTLNKYKEIQPNRIMIFPYKKIDSTMQLINIDEMKTDY PECFNYLSKFKNKLKSRSIQSLKDLDTEWYRYGRHQSLSNFDSGDMIIWSVLTLKSNF VYTEPPILFTGGGQGPYYGIKSNNEKYSVRYIQAILNTPFISKLIEENSVYYRGGYFS AGKQFVENVPIRKIDFEIVEEKQKYAKIVDIVKELEKYSASLAIAVSNSEKTRLGRLI TGKEKQLNNLIEDLYGIR" gene 15204..16826 /gene="" /locus_tag="" /db_xref="1076596..1078218" CDS 15204..16826 /gene="" /product="type II restriction enzyme and methylase" /translation="MIETQDSKKNRGGYYTPQKLTDFIAKWAISTPSDKVLEPSAGDG RFVDSAYKVFQNFDVAFNTDQILAIEYNESEALKIDNNKAKVINSDFFKFFQEKLQNK ETFNVILGNPPFIRYQSIDKEISAKAFDSMIYYGFNPNKMTNLWAPFLLLSAELLTAD GRLGMIIPAELLQVDYAAEIRAYLLQKFSELTLISFNDNLFEGAQQEIVVLLGKIKSK NTGFRFIELNSLSDLETLELNNEATFVKDIEISKEKWLKYFLTPNEINNFKSAISNSK LKLFDDIAEVNVGVVTGQNNFFVVNKEIIDTFDLENDSLIDIVSRAEQINGIELNNSR LKELYNENKKVKLFMPKKVLSNNERKYIDFGESKEYHSGYKTRIRKEWYRVPVSWAPE AFFLRQVHEYPKIVINKTNATNTDTLHKVRARKNYEIGNIALSFLNSLTLLQCELTGR SYGGGVLTFEPGEVRSLKVPYYQFDAVERSMLMKLLSNGEIQQAVDIVDEIVLKNKCN FSKQEILKFKSGWLRLKKRRLNRKKKVYNLSI" gene 17311..18957 /gene="" /locus_tag="" /db_xref="1078703..1080349" CDS 17311..18957 /gene="" /product="hypothetical protein" /translation="LFHIDCNEQSRHLYYKDVYPNLGKIYKTGSNILEFDQLKLSTNV TIPLQWECNHCHNLFNLSISKMFSRIKRDSVYCYECKASFKELFFETDSTIPLSYLTP NYIKEWSSENTVHPTQVDILSDIEVKWSCKNCHGSYTAKICEKDSRSCPYCNDREMLS GFNSLEKTHSYLEIFWDSSNTKSLSKIWYKSTELMNWICPCCSVVFQCSPIEMISRVN LDNRNFQTCPALCDWTDKVFNNIIFHDTPIFLKEWSSKNEISLHRASMYQEYKKYWWN CSKCNGEYRCSIPIRREVPNSCPYCNKEQILKGYNTFADQYPVLAKYWSSKNELEPGN ITLDPLENKRYLWECVSCYMDFKSTFREVLEAYVEIGIAGLSDICPYCTGKLPNPQTE SLNIVKPFLIEEWHKNISNTKPIEEFFPESEIKLWWKCRNCHGQFLARICDREENDDC CPYCSGKKILKGFNTFDVKYPHLMKEWDYLNNILLLDPSEISESNANNVWWICRNNRE HRYKMSVQQRILFNKRSKEPCLICKGRRRKRGHFIPYKQI" ORIGIN 1 ctattttcgt tttttcttgg cctttttaat cttattagct tgacgcttca tggcctgctt 61 catggcaaat tgaccaatct taccctttag gccacctcca aagagctggc tcatatccat 121 atcaccaccc agtgcagaca tgtcaggtaa accaccttgc cccatcattc cttcaagggc 181 agacatatca ggcatgcctc ctggcatatt tggcatgttt ttagggagat tgttagggtt 241 gattcccatt tgcttcatca ttttagtcat atcacctgac atgacaccct gcatcatggc 301 tttagcttgg ttaaaatctt taataaattt gttgacttca acaaagctat tacctgaccc 361 agctgcaatg cgacggcggc gacttggtgt taaaagctct ggccgctcac gctcttcagg 421 tgtcatagaa gaaacaatag cacgtttgcg agcgatttgc ttatcgtcaa ccttaatatt 481 ggctagagca ggattagttg ccatacctgg aatcattttt agcagatctt ccattggccc 541 catgttttgc acttggtcta attgctcgat aaagtcatta aaatcaaagg tattttcacg 601 cattttctca gcaagctcta atgatttttt ctcatcatat tcctgacttg ccttttcgat 661 cagggtaaga agatctccca ttcccaagat acgacttgac atgcggtctg ggtggaaggt 721 ttcaatatcg gtgatttttt caccagttcc ggtaaatttg attggcttac cagttatttc 781 acgtatagaa agggccgcac cgccacgagt atcaccatca atctttgtta acactacccc 841 agtgatatcg agctgattgt taaattcgta agcaacattg gcagcctctt gtccaatcat 901 gctatcaacg acaagaagga tttcgtttgg tttagctagc gctttaacct cacgaagctc 961 gctcattagt ttttcatcaa tttgcaaacg tcctgccgta tcaatcaaaa catagtcatg 1021 gcgattttct tttgcctgcg ccaaaccatt agcaacaata tcaactgctg agtgatttgt 1081 ccccatatca aagacaggaa catttatttg ctgccccaag gttttcagct ggtcaatagc 1141 agccggacga tagatgtctg ctgcgatcat caatggacga gcattttctt ccttgatgag 1201 cttattggct aattttcctg caaaggtcgt tttaccagct ccttgcaagc ccaccatcat 1261 gatgacagta gggattttag gtgatttatc aagctctgcg gtttcggagc ctaagatacc 1321 agttagttcc tcattaacaa ttttaagtat ttgttgcgtt ggatcaaggg tatcaataat 1381 ctcgtgacca acagctcgct cacgtatacg cttgataaag gtcttaacaa ctggaagcgc 1441 aacgtccgcc tccaataggg ctagacgaat ctccttggtc acctcttgaa catcagcttc 1501 agataaggtt ttcttaccac gaatgtgctt aaaaacgtcc tgtaaacgtt gggttaggct 1561 ttcaaatgcc atagctataa ctcctcttaa tctctattgt caatactagt taaaatggaa 1621 attttgtcac gtaaataatg gtcactagga tattttgcaa gaatgtcatc aaatatttca 1681 ctacgcacga tataatcaga atacatatga agcttcattt cataggcttc cagaattttt 1741 tcagtgcgct taatattatc ataaactgct tgacggctaa cgccgaattc ttcagcaatt 1801 tcagccagac tataatcatc agcataatag agctcgatat agttcatctg tttatcagtc 1861 aacaaggcag cataaaattc aaaaagagca ttcattcgat ttgttttttc aatttccata 1921 atccccattt tatcatatca tgagcatttt taacagtggt aaatgatagg attagccttt 1981 tatcaagaag ctttcttaaa gcaaaaatgg ggatagtagc ttgttttgat agctgtccta 2041 aaaattatta aaaatatttt ttgaaatgtg ttgatacact ttgacaagca atagaaaaaa 2101 gaagtggtga accacttcct atcaatgtta ttcaagcatt atcgcttatg attaattatt 2161 ttctaaataa aattcaaagc gatcacctac atattggcta cgcacatatt caaagggtct 2221 accgtctgta aaaaaggaaa cctgagttaa tgctaaaata gcatgcccct tagctacctc 2281 tagataagag gcgacacgtt cactggctat tttcgcgtag atggtttgtt gacttttgcc 2341 gatttcataa ccgtttgagg ttagagtttg gaaaaagtgc tctgtaatat cagttttttt 2401 gacattttta ataaatttct cagggattga ggctacctcg taaactaagg gaaccttatc 2461 tgcataacga atgcgctcca ttcgaataac gtaatccgat tcttctaagt gcaactgatt 2521 tatttctgta tcacttgcta gctgacgttg ataggaaatc agctttgaag atggcttacg 2581 tccctgagaa ttcacaatct ctgtaaagct agtggtccca cgcattctct cttgtacgcg 2641 atgactggca acataagtac cactgccaac acgcctctct agaattccct cctctacaag 2701 cagtgttatt gcctgacgca atgtcatgcg actgacttca aaatgttctg ctaaatctcg 2761 ttcgcttggc aggcgactac caatagtcca gacttctttt tcgatgtctt ttttaatagc 2821 gtcatgaatt ttgatatagg ctggcagcat gctttactcc ttgggggtga tgatggtttt 2881 attttatcat attttcagcc taaattgcag cccaattatt atcaaaagca ttcatcaatc 2941 agctttttca tgctaagact gacaatagaa gatatttgag ggcattcatc ttgatatatc 3001 tctgcaaaaa gattattttt gatcacatca cttgaaaagc taatgccttt ttggtgaaaa 3061 tatgctacaa ttaattgaaa actatcagct aacaaggtgc tggtatataa tgaaagggtt 3121 ataatgactg aaatttcaat gttgaatgat gttcaaaaaa ttatcgttct tgattacggt 3181 agtcagtaca atcaactgat tgcaagacgt attcgagagt ttggtgtttt ttctgaactc 3241 aaaagccata acatcactgc gcaagagctt cgtgacatca atccaatcgg gattgttctg 3301 tctggtgggc caaattctgt ttacgcagac gatgcctttg gtattgatcc tgaaatcttt 3361 gaattaggga ttccaatttt agggatttgc tatggcatgc agctaatcac acatacctta 3421 ggaggcaagg tagtcccagc tggtcaagca ggtcaccgag aatatggtca atcatcatta 3481 cgtttacgct ctgcatcagc attatttgcg ggcactccag atgagcagct tgttttgatg 3541 agtcatggtg atgctgttac agaaatccca gagggctttc accttgtagg agattctaac 3601 gattgccctt acgctgctat ggaaaataca aaaaagaggc tctacggtat ccaattccac 3661 ccagaggtaa gacactctgt ctatggtaat gatattttga agaactttgc tatctctatt 3721 tgtggtgcac gtggtgattg gtcaatggat aatttcattg acatggaaat tgctaaaatt 3781 cgcaaaacag tcggagatcg taaggttctg ctaggtttat ctggtggtgt tgattcttca 3841 gttgttggtg tccttttaca aaaagctatc ggagatcaat taacctgtat ctttgttgat 3901 catgggcttc ttcgtaaaaa tgaaggtgac caagttatgg aaatgcttgg tggaagattt 3961 ggtctcaata ttattcgtgt tgatgcctca aagcgctttt tagatctcct tgcaggtgtt 4021 gaggatcctg agaaaaaacg taaaattatc ggtaatgagt ttgtttacgt ttttgatgac 4081 gaggctagca agcttgaggg cgttgacttc cttgcacaag gaacgcttta cacagacatc 4141 attgaatctg gaacagaaac tgctcaaacg ataaaatctc accacaatgt tggtggtctg 4201 ccagaggata tgcagtttga attaatcgaa cccctcaata cactctttaa agatgaggtt 4261 cgtgctcttg gcacagccct tggtatgcca gatgaagtcg tctggcgtca gcctttcccg 4321 ggcccaggcc ttgctattcg catcatggga gagatcacag cagaaaagct tgaaacagtc 4381 cgcgagtcag atgccatcct tcgagaagaa attgctaaag caggacttga tcgtgatgtg 4441 tggcaatatt ttacagttaa tacaggtgtt cgttccgtcg gagttatggg agatggtcgc 4501 acctatgact ataccatcgc tattcgtgct atcacctcaa ttgacggcat gacagcagac 4561 tttgcccaat tgccttggga agtcctaaag aagatctcag tccgaatcgt caatgaagtc 4621 gaccatgtta accgcattgt gtacgacatc accagcaaac caccagcaac cgttgagtgg 4681 gagtaacaga agcaactatg ttactgcaac aaagatgctg aaaacagagg gttttagcgg 4741 ttaaacggtg caaaaaactc cttagtgata ctgttttgat actaaaaagc tccagacaaa 4801 attaggtgct aaagagagtt attgaattga gcgagtttta cgagcgatac ttattgaccg 4861 aagtacaata aagtaagaga taattgaaat ccttccatca ttttggtgga aggattttgt 4921 gaaatagtgt ttgataaata ggaagttgtg aaggagggta tttatgggta agaataaaaa 4981 atagcatttg gcttctttat aggtgcaata tgcttttgta tagttgcggc tataactttt 5041 ctaaataaaa gctcaagtaa tactatgggt atacgggcag ccataggtgg atccttttca 5101 aacaaaaatg ggagtgagga agacgataat tcttcagatc ggcaaatccc agtttgtcta 5161 aattatcgaa cagtataaaa acaaagcaca tgactttaag attgtaaaat cttttagcta 5221 tgtgcttttt tcgttgcgtg aagtccgtca cgctctgtaa ggtacatgac aaataaacca 5281 ccgatggtca tgattgttaa aagagtcttt gtagctaagt aataagcttt aaaaaccttt 5341 aacgggcttc ttaatgcaga aaagtaaatc aaagaagtag aagcacctca aaaaataatg 5401 tgttaatgta attagcttgg ttgtgcaaca gtcatgcttt taagctaaca caaaggcaaa 5461 agcttataca tctaagggca taaagttggc aatgatttta ccaataatac gcggattgtc 5521 atcaaaggca gcgaatttat cagggtattt tttgttcaat gagaccaaac gcagaccatt 5581 ttcttcacga tatacttttt tgatataggt ttgtccttcc cactcaacag catagatagc 5641 accgtcataa tcaaaactat tctgtttgat gagaacaacc tcgccattca aataggttgg 5701 ctccatggag tcaccaaaaa cccatgaagc aaaatcataa tctaactgct catcgtaaaa 5761 cacaacatca aaattcccat caccaaagta agaatagcca gtccctgcag ataacctctc 5821 gtaaacacga taagggtaaa gtgtcttttg cttagctggt aaagcaatca ttttttcttg 5881 ttgctcaagc aggctctcag aatagctgat aaccttttct ttattaaagg cgcttaactg 5941 actataggga agtaaaagac gattttcctg ataaaagtac tcagcaggta attgaaaaat 6001 ctttataagc tcttcaaaat gtttttgatt tggcttattt ttctcctttt cccaattaga 6061 aatggtcatt ttattaactc ctaaaagctc tcctagctgt tcttggctaa tatgccttga 6121 taaacgcgct gtttttaatt gaataccaga aaacatcagc atgaatctcc tttgttagta 6181 tactttagta aagtattaac tttactaaag tatagcatag cttataagaa tattcaagct 6241 ttttatgctt atatcgaaaa gacagtagct gtcttaggtt taatggcaaa catgttatac 6301 ttatatagag ccatcaaaat ataataacac aaacaatggg aaagaaaaat gcttagcaaa 6361 caaaaattgt cacttgaaat cattcattac ctgatatccg gtcttctaac aaccattctt 6421 tattttgttt tgcggtatgt catctattca tggctacatc aggccaccat atcagcaggc 6481 tttgccaatg ttatagcgat catagctgcc ttcttgatga atgatagcta tgtttttaag 6541 cagacttctg acaaacgctt gtttagattt gccatgtttt tcctagctag agtagtgacc 6601 ttaggcttgg acatgctatt agcctattta ttggttgaga aatacccaga ggtcattgga 6661 agccttgttg agcatgattc tgaacgcatt aattctgttg aaagcatttt gagccaagcc 6721 ctaatggtta gcttgaattt tgctattagt aaatactata tttttaaacg acatcgcagc 6781 agataaaaaa cagaaaacta aaaatttatg tactttacat ctaacagtac ttaaaccctt 6841 gatacatcta taattgaagc ataaagtaca taatttaaaa aatgtacttt atttttgttt 6901 tgtacattat ttgaaagtgc aatatagtcc ataatttagt tacgatattc cagtttgagt 6961 aggatttcaa ttgtacaaaa tgaggtagaa aacaatgatg aagtagtagg gcaaattgta 7021 cattttttga tgattaaatt ttataatatt aaataattgg tgactgtaac ctaatagtta 7081 cattcttttt aaacgttggt ggtataatta gctgaaggag ttttttatga ctgaagattt 7141 aaacccaagt attgttcctc gtttaaatcc taaactgtta ccagctgcaa ccattattaa 7201 aaattttgtt gatggtgaac cagactgtaa ctatgaaatc tatttgctag aattattaaa 7261 taattcaaca cattttttga aaaaaggtgg ctcatgtttt tctgcaccct ccgatgaaag 7321 tcatggtcag tgtgatgcga tatcaaaaga ttatgatata gactttaagt tgttatcttc 7381 cagtactagg ctacaggcta gtaatttatt ttcctatggt attagcaacc ttggaaacgg 7441 aataactgct attactgaga gtaaaaagaa gactggggaa attaaagcca ctcaaattca 7501 tgtagcattt caaacaaaag atgtggcaga attgatacaa ttgaaagaag attttcaaaa 7561 tagcagaaag catggtatcg aaaaagatat tatcaatgta ttgaacacac ttgaaaaaaa 7621 gaaaaatata atgctatttt ttccgtatac ttgtgaattg gaaggttatc ttgaaactga 7681 aaatttagac gatataattg ttagtgagct aaactattat tttaattcac tttttgtgta 7741 cagaagttta aaaatgaaag agtttgacac ctattttgta actatctttc aagaaagatt 7801 ttatattttt tctattcaag atgataccct caacttagta gagaaaatag attgtgtatt 7861 actgcctgca tttattaaat taaagaatta ccatctataa ggaggaacag ctattgatca 7921 atccagattt ttataaaaga ctagcaacaa tattttgtgg agatgaaatg gagttgttta 7981 cttataaatc aggacctcag ctagtatctt tttttaatac tcatttcaat gcccacgata 8041 gttataggca aggttttccc acgagatggg tatatgtgaa tgacaaactg ttggattttg 8101 cctctaaagg tattatcaat tcttttttta atcttatact cagtaaacaa tatcttttaa 8161 cagaacgtca gataagtgaa gtggacgcga tagaacatca gcaaaaaata atagatgagt 8221 tagataaaat ttgctctgtt tattcgctaa agctttcaaa aaaagggaat gaattttcct 8281 tagttgaaat tgatttagat ttagtagaga ttggaaaagg tggatttgct gatatttatt 8341 tccaaaaatc tacaggattg gtgttaaaaa aactaaatga ggaatctatc aggcaccaat 8401 ctttgagaag tcgcttaaaa agagagtacg aaataactaa atcttgctcg gatatcggaa 8461 gtattatcag agtatttgat tttgatagaa gcaattgttc gtacacaatg gaaaaagctg 8521 attgtacatt ggtcgattat attgaggaaa gcgagcttac agaggagtct atgttcaata 8581 tattaagaca agtaatttat actatttcac ttgttcatca aagagatgtc ctgcatagag 8641 atataagtcc aactaacatc ttttttgtaa atgggataat taagattgct gattttggtt 8701 taggaaaaaa tcttaatacc ttaacttctc atcaaacaat ggatacagcc tcttttggac 8761 agctttttta ttgtgcacca gagcaactaa cactcttaaa agatgcagat aaacgaagtg 8821 atgtttattc acttggacgt attatcaatt ttgttatgac aaaaaatcct aatatttttt 8881 cacattcact tcgctctatt agtgagaaag ctaccaattt agaacctgat tatagatatc 8941 aagacgctac tgaaatgttg aatgcgttga attcatggtt gaatattagg agtgacgaaa 9001 ctttcaagaa aacaatatgg gaaaagattg ataaaggtgt ctttgataat gatatagaaa 9061 attatatata tgaaatgtca gcaaaagatt tatgccaagc ttgtatcaat aaaagaaata 9121 tttttatcga ttgcttactg agctttatga aattagatga cacacatgca aattatattg 9181 ttcagacgat ccattctaac tacgagcaat atttgaaaca gtttgaagat gcagatcctt 9241 ttgccactct ttcttatcgt gtcttaagag gtaatttctc attcactgtt aatgaagttg 9301 ctgcaaggat tttaaaatac gttgcacatg tagttaatcg atttagtgct aaacgaatga 9361 tagatagctt agttgatgaa gggctagagc cattgattga aactatattg gaaagatagt 9421 ttgagaggaa atgttatgac aaatgatgaa tatttcaatg agatagaaaa ttatttcaaa 9481 aaactaaaat attataaaga gaaatcaaag acaatcgtcg caggtattat ggatgaaaat 9541 tctactgaag ttgatatgtt ttttatttct gcgcttaata gacgcgtcca gtttatggat 9601 ggaataatag agttgttaaa gacaagaaat ttaacttgtg cgggaatttt agttcggacg 9661 cagctcgata accttatgag agtttttgct gcctttatat cagatgatag aagaaaattt 9721 atccaagctt ctttaaatgg taaaggtatt aggaatatga aagataacca aaataaaaaa 9781 atgactgatt tctatcttaa gaaaagaatt tcagagtatt atcctgagat tgaagaaatt 9841 tacaataaat catctggtta tgttcattta tcagaggtcg cctttcatca agctttttgg 9901 atagataaat ctgatggcaa ggatagtttt agattctctg taggtttatc tcctagagag 9961 gagctaaacc ccgttctaat tgaatgtgca gaagtattct gtcactttac agaaattgaa 10021 tatgattttt atcaaaaaat tattgattcg aaaaaaatat ttgaccagcg agaaaaaaat 10081 attgacaaat ataacaaata acgatatatt taatttgtaa tatattttat atcgttttaa 10141 aactataaaa gaattgacac aggtgacaga tgtgattgct tgtgtttttt tatggataac 10201 tggaggttat tattatggct aaatatattt ttcctgataa aactgatttg gttaattatc 10261 tttatgaggt gctagataat ccctcaccta ttaaaattca aaagacacta tatttgttgt 10321 tcgcttacta tggtgcaacc tatggtaaaa tcaatttatc caacgatagt gagttagata 10381 tatcaaatta tacagagttt ttgtttgaac ctaactttga agcatggatg tatgggcctg 10441 ttgattttga agtatacgaa cgtaataaaa atggagaata ctctgctcag aagttgagtt 10501 ttgaatcgtt aaataacgaa ttaaaccttt cagaaaaaca aaacattgtc aatttttcgg 10561 ataacattat tcgtcaaaca aatgtggcag atgatttctc cttagtggat cggactcatg 10621 aggatgaatc atggagcata ccttatgaaa aaggtaatgg agctgcacat attccaatgg 10681 atccttatca gatagttgag gaatattcaa caaaatatgt tcagtaatct aaatattggg 10741 attaaaacag gtctaaaaag tcctgttagt ataaaatttc agaacaaggt gtttaattct 10801 gagacttata cacctcctac aaatattaac cttaaagatg taaaagttga agtagtattt 10861 atgaattctg ccaaaaaatt tataaattta ccagacctta aatttacaaa taaaaaagcc 10921 gatgtggggg aagaagaccc caagacactt ttaaaccttg ataaacttcg ggaagatcag 10981 aatttcttaa agtataattc ccttcctatt acaatatctt ctaatgaaca aggtaatagg 11041 attaaaggga tactttataa cttccttgag aaagattttg ttgatcagca tgaattctgt 11101 tttagaaaat ctgcaatcga agatgacttt gatgttacta atatccacaa tggacgtttt 11161 agagtaattt gtttgtacag aataaaacca agtacacata aaaaagaaag acgtaagcat 11221 tatttagaaa ttgctatttt agatccatat cacctgttta ttccaagtaa actaaaagta 11281 aaagaagaga gttccaataa agttattaca cttgatagag atgcagctat gaatagagtt 11341 tataatagtg ttaaagatta taataaagac tttgatatct gaaagtatac caacttggta 11401 attctttcgg atatttttta tatatgacta caaggaggac tattctatgt gggttgaacc 11461 agaagatttt gcatggactt atgcaaaaac aaatgacttt gattggttta aaaaacgctt 11521 gatgcactgg attgaatcta gagactatga cggcatacct gaaaatacta aaaaggtttt 11581 gaaggaagtt cgtcaatcat ttatcaatca acgacaaaat ggacatagaa aagctgagct 11641 acaaagtgag tactgggata aggtaattga ctatctagca gtagcttatt acgaagaacg 11701 tccaggtcat ctctttacaa caagtgtcac cgcacttaat agaccaatag atgagttcag 11761 taaggatatt cagcggatta tatggcgttt tgctgaaaca gaggatgtag aaggggcaat 11821 caagtgctta gttgggtttg tccgtccata cttgaatgag attcatcttt ttaagttaga 11881 accagtcttt acagatgcca gtgagaagtt gaagaaacaa cgtagtcaac aaattcacaa 11941 agaggatatg gataacgaat attggaaaat aatgatctat aatttggata atgtttttgt 12001 tagactcgaa aattacaaaa gcaagacagt ttattttaat tacttgattc aagcggagtt 12061 ggaaaaacat aaataagttt ttaaaatttt tttgaaaaaa ctacaaagag tatcaaaatg 12121 agaccgttga gcaatcaaaa tatttgacta tctcattttt tcttatcatt tgctatggta 12181 taattgagat attcattata tgtgaattat atatcaaaaa taggggaaaa ctatgaaaaa 12241 tcaaattaag gctttagtta ataaatttac atccaataag gaatattatc aagaaagtac 12301 atatgacgaa acaagtacta ggattgactt tttaaacaaa ttttttgaaa tatttggttg 12361 ggatgttagt aacaatgcct tattacctga aaacttgcgc gaagtaatac atgaagctac 12421 tattgaagtt gaagaaggta atataacaaa gaaaaagaaa ccagactatc aatttcaaat 12481 tcaaggaaag ggagtctttt ttgttgaagc taaaaagccg tcagttgata ttagtgtctc 12541 tcaaaaatct gtttttcagc tcagaagata tggttggagt gctggaatgc aatactcaat 12601 tttaactaat tttaaagaaa ttagtttcta cgattgtacg ataaagccaa atgagtctga 12661 tgatgtgaat gtagctagaa tagctaagtt taactatact gaatacgtgg agaagatcga 12721 agaaatagct aaatttttag aaaaaaatat agtagagaaa aatgaatttg atttatctaa 12781 cagtagacaa tttagtgatt ttgatgttta ttttcttaat caaatcaaat catggagata 12841 ctctttagct caaaatataa ttgagcataa tgaaataatt gatattgaag atttcaacgt 12901 ctttattcaa cgttttataa ataaggtgtt atttctcagg atttgtgagg acacaaatct 12961 tgaagaatac gaacaacttc aaaaaataaa aaatattgtc gaactacaag agctatttgc 13021 aaatgcagat aagaaataca actcaggtat ttttcatcta cttgatgaaa atatatatac 13081 tgtagatttt gagataataa aggtaatctt tgctgagtta tattatcctc tgagtccata 13141 tgatttttct gtaattcctc catcaatatt agctaaagtc tatgatgtat tcctatctga 13201 aagatttgaa attctaaatg atgaaataaa gttagttaaa aagccagaag ctattgattt 13261 ttttggagca gtaactaccc caaaagaaat agcagatctt attgttaaag aatcttttga 13321 gattcgttca gaaaagaatg aaataatact agaagaattt aaaatagcgg atatttgttg 13381 tggttctgga atttttttac taagtgctta tgagtattta caaaatatta tttatgattt 13441 ttctatcaag cgattacaac aatcacttga tgatggtgta ttagtcaaag aacaaaactc 13501 atatcagtta tcatttaaaa caaaaaaaga attattaaaa agtgctatct ttggtgttga 13561 cattgacttg agtgctgtag aagtttgtaa attttctttg ttactctctt gtcttagaaa 13621 tattagtttc actgaattag cacaaataaa gcaagaatct ctcttaccga atttagacaa 13681 taatataaaa tttgggaatt cattagttga tgataaattc tatgattatt attccacttc 13741 taataattca gataatctat tggatatagt aggaaaaata tcaccatttg attttaaaga 13801 agaatttgga aaagatatta aatttgattt aatcgtaggt aatcctccat atactagatc 13861 tcaaaaattg gcaaaatact caccaataga atatcaatat tttaaatctt tagcttccaa 13921 ctataaaagt gctcaaatat catcacttga taaataccat ttatttgttg aaagaggtct 13981 tcacttatta agagaaaatt caggtgtttt aggttatatt atccctaata gatttattaa 14041 agaaaaaaat cagaatacat ttagacatat tctttttgaa aacagatgtg taaaaaaaat 14101 aatcaattac aatgaaattc agctatttca cggtgttagt gcatacactt gtttgctatt 14161 tcttacttcc gatagaaatc ataaaactga atatgtttct ttgtctctaa aacaatcaat 14221 tccagttagt gagcagtttg ggttgagtga attctatgac acagattgtt taactagtga 14281 accgtgggag ctttatagta aggaaactag acagtttcta aaacttactt cggatattaa 14341 taaattttgt aaattacatg acttaagtga tattagcgtt ggattacaga caagtctgga 14401 tgaagttttt ataatagaag cagattctag tgatgatgat ttttattatt tttcaaaaaa 14461 tggaattaaa tataaagttg aaaaagatat tgtaaaacca gcaatttata gagttacatt 14521 aaataaatat aaagaaattc aaccaaatag gattatgata tttccatata aaaaaattga 14581 ttcaacgatg caacttatta acatagatga aatgaaaaca gactatcctg aatgttttaa 14641 ttatctttct aaatttaaaa acaaacttaa aagtcggagt attcaatcac taaaagattt 14701 ggatacagag tggtatagat atggaaggca tcaaagttta agtaattttg atagtggcga 14761 tatgataatt tggtccgtac taacgttaaa atctaatttt gtatataccg agcctccaat 14821 tttatttact ggcggagggc aaggtccgta ttatgggatt aaatcaaaca atgagaaata 14881 ttcagtaaga tatattcaag ccatcttaaa cacacctttt ataagcaaat tgattgaaga 14941 aaacagtgtt tattatcgtg gaggttattt tagcgcaggt aaacaattcg ttgaaaatgt 15001 tccgataaga aaaattgatt ttgaaatagt ggaagaaaag caaaaatatg ctaaaatagt 15061 tgatatagtc aaagagttag aaaaatattc tgcgagttta gctatcgctg tatctaattc 15121 tgaaaaaaca agattaggga gattaattac aggtaaagaa aagcaactta ataatttaat 15181 tgaggatctt tacggaatta gataatgatt gaaacacaag atagcaaaaa aaatagaggt 15241 gggtattata caccccaaaa attaactgat tttatcgcaa agtgggcgat ttctacacct 15301 agtgataaag ttcttgagcc aagtgcagga gatggtaggt ttgttgattc tgcatacaag 15361 gtattccaga attttgatgt tgcatttaat acagatcaaa ttttagcaat agaatacaat 15421 gaatcagaag cacttaaaat agataataat aaagccaaag taattaactc tgattttttt 15481 aagttttttc aagaaaagct tcaaaataaa gaaactttta atgttatttt aggaaatccg 15541 cctttcatca gatatcaatc cattgataaa gaaataagtg ctaaagcatt tgatagtatg 15601 atatattatg gttttaatcc aaataagatg actaatttat gggcaccatt tctattgttg 15661 tcagccgagt tacttacagc tgatggtcgg ttaggaatga ttattccagc tgaattactt 15721 caggtagatt atgcagcaga aataagagct taccttctcc aaaagttttc agaattgacc 15781 ttaatctcat ttaatgacaa tttgtttgaa ggtgcccaac aagaaattgt tgttttatta 15841 gggaagataa aatctaaaaa tacaggtttt cgatttatcg aactaaatag tttaagtgac 15901 ctagagacat tagagctgaa taatgaagct acatttgtga aagatattga aatttcaaaa 15961 gaaaagtggt tgaaatattt tttaacgcca aatgaaatta ataatttcaa atcagcaatt 16021 tcaaacagta aattaaaatt atttgatgac attgcagagg taaatgtagg agtagtaact 16081 gggcaaaata atttctttgt tgtaaacaaa gaaattatag atacttttga cttagaaaac 16141 gatagcttaa ttgatattgt cagtagagcg gaacaaataa atggaattga gctaaataat 16201 tcaaggctaa aagagttgta taacgaaaat aaaaaagtaa agctttttat gcccaaaaag 16261 gttctaagta ataatgagag aaagtatata gattttggtg aatccaaaga ataccattca 16321 ggatataaaa cacgaatccg caaggaatgg tatagggttc cagtcagttg ggcaccagag 16381 gcattctttt tacgtcaagt acacgaatat cctaaaatag taataaataa aacaaatgcg 16441 acaaatacag atactctgca taaggtaaga gcgcgaaaga actatgaaat cggaaatata 16501 gctctgtcat ttttaaactc actgaccttg cttcagtgtg aactaactgg tcggagttat 16561 ggtggtggag tattaacttt cgaaccagga gaagtacgtt ccttgaaggt gccatactat 16621 caatttgatg cggttgaaag aagtatgtta atgaaattac tttcaaatgg tgaaattcaa 16681 caagcagttg atattgtcga tgaaattgta ttaaaaaata aatgtaactt ttcaaaacaa 16741 gaaattctaa aattcaaatc gggttggttg agattaaaaa aaaggcggct caatagaaaa 16801 aagaaagtat ataatttgtc tatctaaaaa caaagaacat agaacatatt atcccactcg 16861 atggaattaa tatgttctat gttcttttat taccattata aaggtaatta tgattttttt 16921 actgagtaac tttataaaat ttatatagta agtttttata aattttcgat gttgacaatt 16981 tcttcgaata aacgtagata ttctttttgt ttttcttggg gtacaagtag aagtctatta 17041 tgaaatttct caaagagtgg gtcaatagag ttcgtattgt ttttataatc ttgtaaaaaa 17101 ctgctaaggg ataaatgata tctatacaaa gtatcctaac tttgagcaat ttataaattt 17161 taacatcgaa gatcaattaa cgattaaaga tgaaatacaa aatctctcat ttgcttcaaa 17221 acgtattttt tcctataagt gcccgacttg tcaggaaaat tggagagata tagcaaaagg 17281 tgctagatta gggcaaagcg aaaatggtga gttgtttcat attgattgta atgaacaatc 17341 gcgacactta tattataaag atgtatatcc aaatctagga aaaatttata aaacaggaag 17401 taatattctt gaatttgatc agctaaaatt aagtacaaac gttacaatac ctcttcaatg 17461 ggaatgtaat cattgtcata atcttttcaa tctatcaata agcaagatgt ttagccgtat 17521 aaaacgagat tctgtttatt gctacgaatg caaagcctct tttaaagaac tattctttga 17581 aacagattca accattccat tatcttattt gactccaaat tatataaaag agtggtcatc 17641 agagaataca gtccatccaa ctcaagtaga tatcttatcc gatattgaag ttaaatggag 17701 ttgtaagaat tgtcatggta gctacactgc caaaatttgc gaaaaagact cccgaagttg 17761 cccttattgt aatgacagag aaatgctaag tggttttaac agtttagaaa aaactcacag 17821 ctatcttgag attttttggg attcaagtaa tacaaaaagt cttagtaaga tatggtataa 17881 atctactgaa ctaatgaact ggatttgtcc atgttgtagt gtagtttttc agtgcagtcc 17941 cattgaaatg atttctaggg tgaatctaga taatcgtaat ttccaaacat gccctgctct 18001 gtgcgattgg acagataaag tatttaacaa cattatattt catgatacac caatttttct 18061 caaagaatgg agtagcaaaa acgaaatttc tcttcatcga gcttcaatgt atcaagaata 18121 caaaaaatat tggtggaatt gttcaaaatg taatggcgaa taccgttgct caatcccaat 18181 tcgacgtgaa gttcctaata gctgtccata ctgtaataag gagcaaatat taaaaggtta 18241 caacactttt gcagaccaat atcctgtgtt ggcaaaatat tggagttcta aaaatgaact 18301 tgaaccaggt aatatcacac tagatccttt agaaaataaa cgttatctct gggaatgtgt 18361 cagttgttac atggatttca aatcaacgtt tcgagaagtt ttagaagctt acgtagaaat 18421 agggatagca ggattatctg atatctgtcc atattgcaca gggaaactcc caaatccaca 18481 aactgaatca ttaaatatag taaaaccgtt cttgattgaa gagtggcata aaaatattag 18541 caataccaaa ccgattgagg aattcttccc agaatcagaa ataaagctct ggtggaaatg 18601 tagaaactgt cacggacaat ttctagctag gatttgtgat agagaagaaa atgatgactg 18661 ctgtccatat tgttctggta aaaaaatact aaaaggattc aatacttttg atgttaaata 18721 cccgcactta atgaaagaat gggattactt gaacaatatc ttattgctag atccaagtga 18781 aataagcgaa tctaatgcaa ataatgtttg gtggatttgt cgaaacaatc gagaacatcg 18841 atataagatg tcggtacaac agagaatttt atttaataaa cgttctaaag aaccgtgttt 18901 aatctgcaaa ggacgtagaa gaaaaagagg gcattttatt ccctataaac aaatttag //