LOCUS NC_010723:12 23225 bp DNA linear BCT 25-AUG-2011 DEFINITION Clostridium botulinum E3 str. Alaska E43, complete genome. ACCESSION NC_010723 SOURCE Clostridium botulinum E3 str. Alaska E43, complete genome. COMMENT locus start: 915697; locus end: 938921 FEATURES Location/Qualifiers source 1..23225 /organism="Clostridium botulinum E3 str. Alaska E43, complete genome." gene 0..1124 /gene="rpoD" /locus_tag="rpoD" /db_xref="915697..916821" CDS 0..1124 /gene="rpoD" /locus_tag="rpoD" /product="RNA polymerase sigma factor RpoD" /translation="MAEGGKESMEQKVKNKAEKGKEDKSAKMAMVKGLIDKGKKNGSL TYKEIMDEIDHIDLSPEQIEKIYEVLEMMGIEVIGGATDAPEVEEEIDLTVLEGIAID DPVRMYLKEIGKVPLLSSEQEIDYAKRIEEGDPVAKKKLAEANLRLVVSIAKRYVGRG MLFLDLIQEGNLGLIKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHM VETINKLIRVQRQLLQELGRDPFPEEISKVMELPVDKVREIQKIAQEPVSLETPIGEE EDSHLGDFIPDDEAPAPAEAAAFTMLKEQLINVLDTLTPREEKVLRLRFGLDDGRART LEEVGKEFNVTRERIRQIEAKALRKLRHPSRSKKLKDYLD" gene 1217..1903 /gene="" /locus_tag="" /db_xref="916914..917600" CDS 1217..1903 /gene="" /locus_tag="" /product="Bcl-2 family protein" /translation="MDLSKRLNWILEYVDKCNTVMDVGTDHGYIPIYLVKNKIVEKAI ASDINKDPLQKAKINASLDGVIDKIDLRLGGGLSLLKKNEVQGVIIAGMGGNLIRDIL EKDINKVRKLDYLILQPAQNPEVLREYLYNSNYEILNEDLCFDEGQFYELFKVKYKMG ENTKLDPIFYEISPVMLKENNKLIKEYIKSKIEKYNKILSFIKEETETAKLRKEEIHT KIKMLEDFIR" gene 2021..2812 /gene="" /locus_tag="" /db_xref="917718..918509" CDS 2021..2812 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MVTVKEISNIIEKKAPIFLKEDFDNVGLMVGDKDKEVKSVLLAL DCTKKVIKEAIDNNVDLIITHHPLIFKKPKSIISGDLLGDKVIDLIKNDISLYSCHTN LDSAKGGVNDMLLELLDLKYSKIIESSNIKGFEECGLGRVIELKKNTSIEEIVNILKE KLNMKNMRVVKGNKDINKLAIINGSGQDFFYMSKELGVNCIITGDTTYHFASDFKEYG INIIDAGHFSTEWLAFIKSLDFLRDSFREIKFIISEKCEDPYDFI" gene 2869..3105 /gene="" /locus_tag="" /db_xref="918566..918802" CDS 2869..3105 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MGDDNNKSFKHTFKNMRRSCRGGRRRGAWFPFFSGPCPWYFCPK SVVGCLILVSLLLCGVNIYGVIIITLLILLFILV" gene 3244..3533 /gene="" /locus_tag="" /db_xref="918941..919230" CDS 3244..3533 /gene="" /locus_tag="" /product="Bacterial RNase P class A" /translation="EESRGSIGQGAG*RPVKAT*RIVQQRYTA*VYLGKGGKAR*ELT SVMVTSRLCKPHLEQDRIERH*GIARPASGCVA*AHWQQ*V*IDDCLIQNPA" gene complement(3591..4052) /gene="" /locus_tag="" /db_xref="919288..919749" CDS complement(3591..4052) /gene="" /locus_tag="" /product="phage protein" /translation="MTYEDLLVYAQNKGLNIKEKKLKFNFKGLYKNSRILINSDIDTD IERKCILIEEIGHHETSFGNIIDYNNLNSKKQELRARRWANEKLIEIKDLICAYNYGV KNKYELADFLGVTEEFLNDTIINYRKKYGICYQIESYLIYFEPNLGILKLV" gene complement(4070..4435) /gene="" /locus_tag="" /db_xref="919767..920132" CDS complement(4070..4435) /gene="" /locus_tag="" /product="transcriptional regulator" /translation="MSYIGNFLKNKRIEKKLTLKDLSDLSGVGPSTISDIETGKALNP RMITLQKLASSLDISVNDFFEERKIDIIDENLIKNVDIEKQKQIDTVAAHLEDKHLTP KKVKLLKDYIDALFDDENW" gene 4690..5199 /gene="" /locus_tag="" /db_xref="920387..920896" CDS 4690..5199 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MELQEINIEGIIEMAVKTAIKEYDKEQKDLDKKKVFHNTKLLMK HYNDLKSHIIYSISDINDITNTDKIELEKEEYDELYILSIKQSKVKTLIMISHIDSSL EVLKKEQRKKGVVEKYLALEKLFIDEKTYEEVAEELNCGVITIRRWVKEMLEELGIYL FGIEGIKVC" gene 5960..6376 /gene="" /locus_tag="" /db_xref="921657..922073" CDS 5960..6376 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MISKLKLEINKMLSQNFHEINIYDDAMKQGFTKPCFFVQVLSSK QVKELNRRYKEVIYFDVNYLSNKESINLDYFNMADTLYKTLEYIEVDNKKYRVSNKEH EISEGILHFKFQVKFNLLKIIEEVNMNKMGVDIVGK" gene 6366..6521 /gene="" /locus_tag="" /db_xref="922063..922218" CDS 6366..6521 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LESKFSKEQLVQSKHFTRNEKDILNALLAEDDYSINDARDVINK FYNMEVK" gene 6522..7832 /gene="" /locus_tag="" /db_xref="922219..923529" CDS 6522..7832 /gene="" /locus_tag="" /product="sheath tail protein" /translation="MAGGTWEKQNKIRAGAYVNFKSKKNNDSSNNERGVMALPLILPF GPEKTIVKIDNETDLLGTIGIEINEESTLMLKEALKKAKTVLLYRLNEGVKATKVLGE LTVTSKWSGSKGNDIRIQIQTNVNDEAKFDVITFLEYTKLDTQTVKNIDELVSNALVD FKGSGELTLSAGVKLEGGEDKPITGKDYVDFLAELELFDFNTVAIPYDDSDTKLVVKE FIKRLRECEGRKVQAVLPNFAEADYEGIISIKNGVYLKDNVHVTNVQVTAYVAALTAG SGYANSNTYALYEGASNVDVRYADSEIKEIIKKGEIIFINNNQQVLIEQDINTLKTFT EDKKSDFRKNRVIRVLDGINDKIKYKWEESYIGKVSNNEDGRNLFKKDILNILETLQG QGALENVVVEDIEVLKGNSNDSIVVNVNAQPVDSMEKIYMTVFI" gene 7851..8318 /gene="" /locus_tag="" /db_xref="923548..924015" CDS 7851..8318 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSNFLNFSDTLSGTEAKGFITVNGRNEELFYAKKLESDAEKTKT TGKTLGSRVEQNKATGWKGTGTLTIYYVTSLFREMMIKYIKTGKDVYFDMTVTNEDAT STVGKQTIVLKKCNFDKVSMAMFDVESEVLEEEMAFTYEDVDLLDKFGKPVIG" gene 8618..9031 /gene="" /locus_tag="" /db_xref="924315..924728" CDS 8618..9031 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNNFEDFLMDSFEDTQEIEREVTIGGKKKLMRFRPISAEMGDMI RKRNRKTKLIKGQRIMETDQDKYVSDLIIETTTCPDLKNSELQASWGVLGAEELLSAM KSKMRDGEFSDWSSIVGEVNGYDKSVNDLIEEAKN" gene 9227..11176 /gene="" /locus_tag="" /db_xref="924924..926873" CDS 9227..11176 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MASMETGLMVMDGMVNQPMRQPVIQMQQIQLIQQQISLTNVLQI NVQKAADEQDKLNQNVNKSTSSMSALAAKASETFKSFFNTESLKKGIETVIGEASKMQ DKMISVQGMLGDKGAGTAYFSHLQKQANESGFSFDELKNNAQSFMGVTKNTENLDKLA NLSERLSLGNSGEGISGAGGAINSMLSGDGSDLKDKFGFNSGDIGILQASKDLDDFTS KFDVLLNEKGLNTSMLDEFNNSASSQFENIKENFNSSLGEAGQGALEAFAPVMEIING MFSNGSFQVFFDLISIGLGVLATTISWICEIVRNNWGIIESILIAIGIYLLGTIIPSV FTLIAQGLAVAATWIIANLPILMVIGAIALLIYALMQCGITTQQVCGFIGGIFMVIFG YIYNRIVFIWNIFASLAEFVENVFNHPLYSIQRLFYNIWNYIVEFVGSALDWIVEKAK SIPFLKDLIGDFSIGSFKVDIPDPPEDYKTVQRMEYKDLGNEFDFGYTKAGNFLSGAG NKLQDVTSKIDNFKNNINLDDIRNKSNNSLGNNSGGIPNDMGGGSDALTSAIDNTNLG NNVSEGSEAIKGINDSVEVSNENLELMNDLAELESLQNFITLTPTVQVTTGDIKEEAD INTIISRIESYMENEMTNSAEGLYA" gene 11176..11838 /gene="" /locus_tag="" /db_xref="926873..927535" CDS 11176..11838 /gene="" /locus_tag="" /product="peptidoglycan-binding LysM" /translation="MSKRYKMRLSINEGREGFILPVLPQEIEISDSGDNKTHNVINLG EVNVINIPKLTKISFKSYFPKNNGPYVNDKHFFRPHEYMRRLNEWRQNAEKVRFIFIG SEFEINDLFSIENLKFTEKGGEVGDIYYSIELKRYKPYYANRAVVIETKNGVIVENYN TTLRPDDKVKINIHKVVEGDTLWHIAKKYLGDGNRYKEIAELNNISNPDLIYPGQVIN IP" gene 11850..12821 /gene="" /locus_tag="" /db_xref="927547..928518" CDS 11850..12821 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNIELLIDDKKSNIYNLSNLIKQVTWKTKRKGSPSSLEVTLLTD ETLSVSNGDIIRFKVDGINIFYGYVFKYSGNEGEEIKLTAYDQIKYLMYNDTFSDVNL KASDVVERILYNLGLTKGIIEDTGYVIPRFNEKDKKLLDIIYKALEKTLASTKRTFVL YDDFGSVNLKDINNMRQELIISENTNLGKYDWSKSIEESYNAIKLVRKNEDSEEEKVY TKEDKDNIYKWGKLQFFKSIDDKVNEAKMEEILKAHLILKNKEKKSLKLKDVLGTDIK LEAKLRGGSGVWVDIKRYGINQIYLIEEVTHKFSKDGHIMDFDLKVV" gene 12825..13154 /gene="" /locus_tag="" /db_xref="928522..928851" CDS 12825..13154 /gene="" /locus_tag="" /product="phage protein" /translation="LASMIEIIKQASVNAINAGNPLDIEFGTIIDDNLTVRIDQKRIL QKDFFVVPESLNRYEIDLTHNHSDTSSALGTIVIREGLKKGDILALLMIEKGSRFLIL DKVGKYE" gene 13147..13554 /gene="" /locus_tag="" /db_xref="928844..929251" CDS 13147..13554 /gene="" /locus_tag="" /product="phage protein" /translation="MNNFSVLPKGGIIKDIDNIKEKKHSSKTYKIKENRIIGFCDEIE ALEQTIYFILNTERYDYLIYPDSYGSELRRTIEMDRGIAESELKRRIKEALTQDDRIE NVDEFIFEYEKDSVLVKFTVFSIYSKLYESVVI" gene 13557..14615 /gene="" /locus_tag="" /db_xref="929254..930312" CDS 13557..14615 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LFEVKEEDLLKEMIDKIPNDLDKREGSSLIYNALAPAAQEISRL RSDMDRFLEYTFASPNIPDEYLDKRCAEHGIERKKATYAVKLGTFYDTEEKLIDIPLN SRFSIDKTTYIAIEKIEKGKYKMQCELIGTKGNYLSGNLLPVEYIERLGSGVLGETIL DGVDTENNESLFNRLMVKVRTPSTSGNKYDYLNWALSVNGVGDAKIFSETNLKGEHES GCVKVVIVDSNKHKASLKLIEDVSQYIEMVRPIGATVSVVSAVEKTINITADINLIKG YNLGVTEKEFVKLLEEYLKNISFKQDYISIARIGEILLNTNGVIDYSNLLINKNTSNI KLADEEIAILGNVSLGVM" gene 14616..16697 /gene="" /locus_tag="" /db_xref="930313..932394" CDS 14616..16697 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LDISNFNEKFNKIEGNIYVIEEKIEQINGVYEGELAHDNINIKT LNVYTGSKLTGEKIESYSISTPSFTPWKTIIKVFSEVTPLYISYETVGDQVEAEDINK LQDTLVFTQQNLNEEIHRATKSENILIDNLNSEVVRSTQVENNIAMNLNTEVNRSKNV EDAINKELSNEVKRAINAEKVLTDNVNTTNSKLTTERDRAEKAEEILTKSINNEISRA KSIEDDIKSKLNEEFNRSKKEETSIVNNLENEVKRAIDAEKILTDNLNSEIYRSKTKE NNIEENINSYKSSNNIEIQKLKEKDIDFQNKKSDLSYVNSELNKRYTKDQTFTREEVL QKIKDIIGTAPEALDTLQEIAKALNNDADFAGTMTKQLTTKVDKTQGKQLTDENYTLE EKNKLSKIEKEANNYVHPANHSADIIVDNPNKRFTNDAEKSKNLESYNKKHEHLNKTT LDRITDNLINKWSDANTHVNDNVRHITDEERKLWNTVSKKSDNGHVHNYNELSNKPLI PTKTSELNNDFGFITQKDIDTSQNHIHSNKSVLDEINKSLIDNWNTVSNKVDKRHKHS ISEINNMPSSLPANGGTASRIYGSMASNDFIRIEGQGKDDNGSLEIATADNGNEPIYV RQYTGSFATISRTLTLLDSNGNTICPGTLNANNLQVCGANVYTTNRKPTASEIGAMAK GPIKWNDLKGV" gene 16699..17313 /gene="" /locus_tag="" /db_xref="932396..933010" CDS 16699..17313 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MYGLNNYGTIKYAEKKLNEEDIKKYFLNLSKYVPSFISDIKEMK TIYNVQGTELGGFLYYLKDLIDQAFIETATWGLIYWENEYGIETNLNSSYEDRREIIK AKKRGSGTTTKEMIKNVAETFSGGEVNVIEDNKNYSFIVQFVGVKGIPKNMQGFKNML EDIKPAHLSYSFKYTFTIWDFIKEKDLKWNSIENKSWNELKVYE" gene 17328..18128 /gene="" /locus_tag="" /db_xref="933025..933825" CDS 17328..18128 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKLTSNYSLKKPDGSDVVNIQDFNDNSDKIDLELKKVDSQLKEK ANLKDVKIFSSLADIGLTQNDMTTDFASNVLKIIKAIGANRRISLYPYQTESNTNLYN SVKTWCGFNTDAFHVIIDTSFNGAENLPNKIEVIPNYNNGNNRVFLGFYDNELGNCRE VATTESFEINLLNGASVYLTDSNYSPYFIRVGQLATITGNIKVSGISDDTVIMRLPQP KGHKWIKTFTNNGIPISFYLSPSGELKIRGASRVDEGDNLPLDFLYRI" gene 18145..18480 /gene="" /locus_tag="" /db_xref="933842..934177" CDS 18145..18480 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MTIEEVDKLNIKNEDGEFTPKTIEKIVEEEIDGETVQTFDYEIV QSAEDYYKEWLNNKNNQPKKEPTENEVLISNIILENAQLKTGLQEQQELTANLLLQIA ELKGGNANV" gene 18473..18607 /gene="" /locus_tag="" /db_xref="934170..934304" CDS 18473..18607 /gene="" /locus_tag="" /product="phage protein, XkdX family" /translation="MYKWIKKFYLMELYTDENLNVFVGSKDITEEEKQEIVNSKVISQ" gene 18721..18921 /gene="" /locus_tag="" /db_xref="934418..934618" CDS 18721..18921 /gene="" /locus_tag="" /product="UviB homologous protein" /translation="LDEIMKMALSQGLGYALFVFLLLYVLKTTGERENKYQSLLDALA EKFNVVEDIKEDVKEIKNKIES" gene 19060..19854 /gene="" /locus_tag="" /db_xref="934757..935551" CDS 19060..19854 /gene="" /locus_tag="" /product="glycosyl hydrolase, family 25" /translation="MRGIDVSDHNGDINFNKVKEDNIEVVYIKATEGTTYKDPYLNKN YNEAKKVGLKTGFYHFLVGSSEPETQAKNFYNNIKDKVNDLKPCLDVEISNFNVMDYV LKFIKKFESLCELPLCIYTSPYFANENLDSRVTKYKCWIAHYEVENPMKTIIWGENYA GHQFTEKGKIKGINTNVDINKFTEDILVEEKKIGYVITDYLPNGYRGNNQFKGIDLEY VLSYFNGIRCYVRSDSNGIWLETQVLPMSKCQELKVKLGNWFYTIK" gene 20002..20166 /gene="" /locus_tag="" /db_xref="935699..935863" CDS 20002..20166 /gene="" /locus_tag="" /product="surface lipoprotein-related protein" /translation="MKEQWYEKAWATILFLFIFYPVGLYLMWKYRSINKIAKILITMF VICLSSTFVS" gene complement(20189..20755) /gene="" /locus_tag="" /db_xref="935886..936452" CDS complement(20189..20755) /gene="" /locus_tag="" /product="acetyltransferase, gnat family" /translation="VSKDNFKKSININIPINSSKIYVNEITLDELIYIYSWSNKEIEE KVTCRPILNKTINETIELYKSLLISDNTYILGLYNINNNELLGKITLFDYNYRNKSLE IGYYLIPKFRKNGYMNEAIKIILNLLFRKLNMNKVYAQTASFNSDSNSLLKLNKFKLD GILREHHELNEVFYDDYIYSILRSEFML" gene 21122..22168 /gene="" /locus_tag="" /db_xref="936819..937865" CDS 21122..22168 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNKKIKKKPTRKKTRCDKKKKTSLLIFMGAIYIIAFLIVTTPFV LIYGPYDKIKKTFITTVLATRHAYLVNDFIPQQTLDKILGKNELEEDSVPANTSIDLN KIDVKNNSGNKVTKYDIHTDRYDGYMLEIENPHKVKVAMTKYLGKLGQKTSEMAEEHN AIAAINGGSFVDKSSDGITYAGTGGQPGGFVISSGKVVYPIGKCNEHSVENVIAFTKK GQLIVGNHTLAELKKLDVQEAMCFREPNVIINGIRQHKKEDYIDGINPRTAVGQKEDG TVLFLALDGRKLSKPGATIYEVQEIMRSRGAINAGMLDGGYSTTMYYKGDVINSPNAW DGERSVATAFYVEQ" gene 22187..23224 /gene="" /locus_tag="" /db_xref="937884..938921" CDS 22187..23224 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKILKNVLVFSFIALLIQQGIFLYIENIYLSSNMDIKIEKSDDS EVRKNEQKEVELKEDVDDLKVSSNGRYIAGLQNGRLKVLDSDENKYKDIKNNVNSNIV FYKWITNSDRIIAIQKIKEKGRNYFEPIAFNAKNGEQIELADFDLNKLRVRIENSEDK VEDIPFSIGTHSLYIKIKKSNEKSDLYRANTMNQLEKKRSNKEIGNIVIPTTAANAIM EMGTQVTILDKPDNLLIPNTKNTKLLGTDINDNVYFASEVDNKVVKIYYAISSDNYKD WKEFKLDNPVNKEDILIDYSGKVYINDNEKKIAVELTSKKTIKYKGELIQTYSKGVIS KNGNKLIKNNI" ORIGIN 1 atggcagaag gaggtaaaga aagtatggag caaaaagtta agaataaggc cgaaaaagga 61 aaagaagata aaagtgctaa aatggccatg gtaaaaggtc tgattgataa gggtaagaaa 121 aatggttctt tgacttataa agaaattatg gatgaaatag accatataga tttaagtcca 181 gagcaaatag aaaagattta tgaagtactt gaaatgatgg gaattgaagt aataggtggg 241 gcaactgatg cgccagaagt tgaagaagag atagatttaa cagttttaga gggaatagca 301 atagatgatc ctgttagaat gtacttaaaa gaaatcggta aggtaccttt attatcatca 361 gaacaagaaa tagattatgc gaaaagaatt gaagaaggcg atccagtagc taagaagaag 421 cttgcagagg ctaatttaag attggtagta agtatagcta aaagatatgt tggtagaggt 481 atgttattcc tagatttaat tcaagaagga aatttaggac ttataaaagc agtagaaaaa 541 tttgactata gaaagggttt taaattttct acttatgcaa catggtggat tagacaggca 601 ataactagag ctattgcgga tcaagctaga actattagaa taccagttca tatggtagag 661 actatcaata aattaataag agttcaaaga caattattac aagaattagg cagagatcct 721 ttcccagaag aaatttcaaa ggtaatggaa ttaccagtag ataaggtacg tgaaattcaa 781 aaaatcgctc aagaacccgt atcattagaa acacctattg gtgaagaaga agattctcat 841 ttaggtgact ttataccaga tgatgaagct ccagctccag cagaagcagc agcatttaca 901 atgttaaaag agcaattaat aaatgtatta gatactttaa ctcctagaga agaaaaagtt 961 ctaagattaa gattcggatt agatgatgga agagctagaa cacttgaaga agtaggaaaa 1021 gagtttaatg taacaagaga aagaattaga caaattgaag ctaaagcatt aagaaagctt 1081 agacatccat caagaagtaa gaaattaaaa gattatttag attaaaaagc acctttacag 1141 gtgctctttt ttatagtata aaaaattata gaattttttg aaatttaaaa aattataggt 1201 agaataggag aacaattatg gatttaagca aaagattaaa ttggatatta gaatatgttg 1261 ataaatgtaa tactgttatg gatgtaggaa ctgatcatgg atatatacca atttatttag 1321 taaaaaataa aatagtagaa aaagcaattg ccagtgatat aaataaagat ccgcttcaaa 1381 aagcaaagat taatgcctca ttagatggag tcatagataa aatagattta cgcttagggg 1441 gaggtctttc acttttaaag aaaaatgaag tacaaggtgt gataattgct ggaatgggtg 1501 gaaatttaat aagagatatc ttagaaaaag atataaataa agttaggaaa ttagattatt 1561 taattcttca accagcacag aacccagaag tattaagaga atacttatat aatagtaact 1621 atgagatttt aaatgaggat ttatgctttg atgaaggtca attttatgaa ttatttaaag 1681 tgaaatataa aatgggtgag aatactaaat tagatcctat attttatgaa ataagtccag 1741 taatgttaaa agagaataat aagttaataa aagaatatat aaaaagtaaa attgaaaaat 1801 ataataaaat tttaagcttt ataaaagaag aaacagaaac agctaaatta agaaaagaag 1861 aaatacatac taaaataaag atgttagaag actttataag ataggaataa aattaaatat 1921 aaatatagca taaaacttac taaataggat attacattaa gaattctaaa atattaatga 1981 tagattaaga gaaaaactat aaatatagtg gagggattta tatggttaca gtaaaagaaa 2041 tttcaaatat aattgaaaaa aaagctccta tatttttaaa agaagatttt gataatgttg 2101 gattaatggt tggagataaa gataaagaag taaagtcagt tttattagca ttagattgta 2161 ctaaaaaagt tataaaagaa gctattgata ataatgttga cttaataata actcatcatc 2221 cattaatatt taagaagcct aaaagtataa ttagtggaga tttattaggt gataaagtta 2281 tagatttaat aaaaaatgat ataagcttgt attcatgtca tactaattta gattctgcta 2341 aaggtggagt taatgatatg ttacttgaat tattagattt aaaatatagt aaaataattg 2401 agagttctaa tattaaagga tttgaagaat gtggactagg tagggttatt gagttgaaaa 2461 aaaacactag tattgaagaa atagtaaaca ttcttaaaga aaaattaaat atgaaaaata 2521 tgagggttgt taaaggtaat aaggacataa ataagttagc aataattaat ggaagcggtc 2581 aagatttttt ctatatgtct aaagagcttg gtgtaaattg tataataact ggtgatacca 2641 catatcattt tgcttctgat tttaaagaat atggaattaa tataatagat gcgggacatt 2701 tttcaactga atggttagcc tttataaaga gtttagactt tttaagagat agctttagag 2761 agataaaatt tataatttca gaaaaatgtg aagatccata tgattttatt taactaaatc 2821 aaagaatata tgcatatatt attgtgaaag caatttatag gtgggtatta tgggagatga 2881 caataataaa agttttaaac atacgttcaa aaatatgagg agatcttgta ggggggggag 2941 aaggcgaggt gcttggtttc cattcttttc aggtccatgt ccttggtatt tttgtcctaa 3001 atctgtagta ggatgcctaa tacttgtatc actactttta tgcggggtta atatttatgg 3061 tgtgataata atcactttat taatcttatt atttattttg gtataaaata aatctattta 3121 ataactttaa cacctgtttt aataattata aaaaatatta aattttattt gtaattatta 3181 aataactatg atattatata tcttgcgagc aaaacgtgca atcgctgctg ggcttgaccc 3241 aggagaggaa agtcggggct ccatagggca gggtgctgga taacgtccag tcaaggcgac 3301 ttgaaggata gtgcaacaga gatataccgc ctaagtttac ttaggtaagg gtggaaaggc 3361 gaggtaagag ctcaccagcg tgatggtgac atcacggcta tgtaaacccc acttggagca 3421 agaccgaata gagaggcatt aagggattgc ccgtcccgcc tccgggtgcg tcgcttgagc 3481 tcattggcaa caatgagtct agatagatga ttgcttaata cagaaccccg cttacggctt 3541 gtctcgtaca aatatgaaga acactaggtt aacgtctagt gttcttttta tttaaactaa 3601 tttcaatatt cctaagtttg gttcaaaata tattaaataa gactctatct gataacaaat 3661 accatatttt tttctgtagt taataatggt atcatttaaa aattcttcag ttactcccaa 3721 aaaatcagct aattcatatt tattttttac accataatta taagcacaaa ttagatcttt 3781 tatttcaata agtttttcat ttgcccatct tcgagctctt aattcttgtt ttttactgtt 3841 aagattatta taatcaatta tatttccaaa ggatgtttca tgatgtccta tctcttcaat 3901 tagaatacat ttacgttcta tatctgtgtc aatatcagaa ttaataagta ttctactatt 3961 cttatataat cccttaaaat taaattttaa tttcttttct ttaatattta accccttatt 4021 ttgagcatag acaagtaaat cctcatatgt cattaaatta ctcatgcaag ctaccaattt 4081 tcatcatcaa atagagcatc tatgtaatct tttagtaatt tcaccttttt tggagttaaa 4141 tgtttatctt ctaaatgtgc tgcaactgta tcaatttgtt tttgtttttc aatatctaca 4201 ttttttatta aattttcatc tataatatca atttttcttt cttcaaaaaa atcatttacg 4261 gatatatcaa gagaagaagc tagtttttga agtgttatca ttcgaggatt taaagcctta 4321 ccagtttcta tatctgaaat tgtacttggt ccaacaccac tcaaatctga taggtctttt 4381 aatgtaagtt ttttttcaat tcttttattt tttaaaaagt tacctatata actcatataa 4441 atcactcctt tatatttatt ccggtttaca gaaatataat atcatttaat atggaaaaag 4501 taaacaattg tatacagtaa accgaataaa tgagagaaaa tgtatgaaaa tcaagctaaa 4561 ataccgggaa aacgtaataa atcagatttg ctcaaacggc aaaccgtata taaaatgtat 4621 ttatagatta attagaattt cgatatgttt taaaacaaag tttaaatttt attgaggggg 4681 agtaaacatt atggaattac aagaaattaa tatagaagga attatagaaa tggcggttaa 4741 aacagcaata aaagaatatg acaaggaaca aaaagattta gataagaaaa aagtttttca 4801 taataccaaa ttactaatga aacattataa tgatttaaaa tctcatatta tttattcaat 4861 aagtgatata aatgatataa caaatactga taagattgaa ttagaaaaag aagaatatga 4921 tgaattatat atattaagta taaaacaaag taaagtgaaa acattaataa tgatatcaca 4981 tatagattct tcattagagg tgttaaaaaa agagcaaaga aaaaaggggg ttgtagagaa 5041 atatttggca ttagaaaaac tatttataga tgaaaagaca tatgaagaag ttgcggaaga 5101 acttaattgt ggtgttatta caattagaag atgggttaaa gaaatgttag aagaactagg 5161 aatatactta tttggaatag aaggaataaa ggtatgttaa aatataatga caaatagatg 5221 aaaaaaagat gctattttaa tgaaataata accatgagat aatggtattg tggaaaagta 5281 agaaaacaca aaaacaataa ttaaaatatg gttatatgag aaaagcactt gtatgaaaat 5341 atgagtgctt ttaactataa taaagctaaa ttgtataaat gaaatgttgt tttgaaaaat 5401 agatgaaaaa aagatgttat tttaatgaaa taataaccat gagataatgg tattgtggaa 5461 aagtaagaaa acacaaaaac aataattaaa atatggttat atgagaaaag cacttgtatg 5521 aaaatatgag tgcttttaat tataataaag ctaaattgta taaatgaaat gttattttga 5581 aaaatagatg aaaaaaagat gttattttaa tgaaataata accatgagat aatgatattg 5641 tggaaaagta aaaaaagaca tatgatttta ggtacctaaa aatatatata aatttagaag 5701 tcttatatta ttaaggcttt gttttgagta gatgttaata tatgtaatag acaaagtggt 5761 attgtaattg gattttgaga atacttaatg agtattgtta catttatcgc ttgtctcaat 5821 tttatattgg gagcaagcta aaataggact atactcattt ttagtattca taagttcaat 5881 tactcagacc actttgctta tacatgtatt aacacacaac cttaaatcaa agcagtactt 5941 gaagggaggt gataatttga atgataagta aattaaagct tgaaattaat aaaatgttat 6001 ctcaaaactt tcatgagata aatatatacg atgatgctat gaaacaaggt tttactaagc 6061 cttgtttttt tgtgcaagta ttatcttcaa aacaagtaaa agaattaaat agacgatata 6121 aggaagtcat atattttgat gtaaattatt taagcaataa agaaagtatt aatttagatt 6181 attttaatat ggctgatact ttatataaaa cacttgaata tatagaagtt gataataaaa 6241 agtacagagt atctaataaa gagcatgaaa tatcagaggg aatattacat tttaaatttc 6301 aagtaaagtt taatctatta aaaatcattg aagaagtaaa tatgaataag atgggagtag 6361 atattgttgg aaagtaaatt ttcaaaagaa caattagtac aatctaaaca ttttacaaga 6421 aatgaaaagg acattttaaa tgcattattg gctgaagatg attatagcat aaatgatgca 6481 agagatgtaa taaacaaatt ttataatatg gaggtcaaat aaatggcagg tggaacatgg 6541 gaaaaacaaa ataaaataag agcaggagct tatgttaatt ttaaaagtaa aaagaataat 6601 gatagtagca ataatgaaag aggggtaatg gctttaccat taatattacc ttttggacca 6661 gaaaaaacaa tagtaaaaat agataatgaa acagatttgt taggaacaat aggaatagaa 6721 ataaatgaag aaagcactct aatgcttaaa gaagccttaa agaaagcaaa aacagtttta 6781 ttatacagac ttaatgaagg tgttaaggct acgaaggtgc taggagaatt aacagtaaca 6841 tcaaaatgga gtggaagtaa aggaaatgat ataagaattc aaattcaaac caatgtaaat 6901 gatgaagcta aatttgatgt aattacattc ttagaatata caaaattaga tacacaaact 6961 gtaaaaaata ttgatgagtt ggtatctaat gcacttgtag actttaaagg atcaggtgaa 7021 cttactttat ctgctggagt aaagctagag ggtggagaag ataaacctat tacaggaaag 7081 gattatgtag attttttagc agaattagaa ttatttgatt tcaatactgt agcaataccg 7141 tatgatgatt cagatactaa gttagttgta aaagagttta ttaagaggtt aagagaatgt 7201 gaaggaagaa aagttcaagc tgttttacca aactttgcag aagcagacta tgaggggatt 7261 atatctataa agaatggtgt gtatcttaaa gataatgtac atgtaactaa tgtacaagta 7321 acagcatatg tagcagcatt aacagcagga tcaggttatg ctaattctaa tacttatgct 7381 ttgtatgaag gtgcaagcaa tgttgatgtt agatatgcag atagtgaaat aaaagagata 7441 atcaaaaaag gtgaaataat atttattaat aataatcaac aagttttaat tgaacaagat 7501 attaacacat taaagacttt tacagaggat aaaaagtctg actttagaaa aaacagagtt 7561 ataagagttt tagatggaat aaatgacaag attaaatata agtgggaaga atcttatatt 7621 ggcaaagtaa gcaataatga ggatggaaga aacttattta agaaagatat attaaatatt 7681 ttagaaacat tacaaggaca aggagcatta gaaaatgtgg ttgtagagga tattgaggta 7741 cttaaaggaa attctaatga ttctattgtt gtaaatgtta atgcgcaacc agtagatagt 7801 atggaaaaaa tatatatgac tgtatttata taatgattgg aggaatatta aatgagtaat 7861 tttttaaatt ttagtgatac tttaagtgga acagaagcaa aggggttcat aactgtaaat 7921 ggaagaaatg aggaattatt ttatgctaaa aagttagaat cagatgcaga aaaaactaaa 7981 acaactggca aaactttagg cagcagagtt gaacaaaata aagctacagg ctggaaagga 8041 acaggaacac ttacaattta ttatgtaaca tctttattta gagaaatgat gataaagtat 8101 attaaaacag gaaaagatgt ttattttgat atgacagtta ctaatgaaga tgcaacgtct 8161 acagttggaa agcaaacaat tgtattaaaa aaatgtaact ttgataaagt aagcatggct 8221 atgtttgatg tagaaagtga agttttagaa gaagaaatgg catttactta tgaagatgtt 8281 gatttattag ataaattcgg aaaaccagta attggttaat gttataaatc tactttgttt 8341 tagcagaata cgttgatata ttcataagta aaggtggact gagtaattga acttagaaat 8401 actaaaaatg agtatagtct cattttagct tgctcccaat ataagattga gacaagcagt 8461 aaatgtgaca atactcatta agtattctca aagtccaatt acaatgccac tttacctatt 8521 gaatatatca acgtatgtta aaacagaatc ttatttatgc tttcagtatt aaatattagt 8581 gtaaaaacaa aaaacgatta gtgaaggagt atggaataat gaataatttt gaagattttt 8641 taatggatag ttttgaggac acacaagaaa ttgaaagaga agtaacaata ggtggtaaga 8701 aaaagctcat gagatttaga cctatttctg ctgaaatggg agatatgata agaaagagaa 8761 atagaaaaac taaattaata aaaggtcaaa gaataatgga aacagatcaa gataaatatg 8821 tatctgattt aataattgaa acaacgactt gtccagattt aaaaaattca gagctacaag 8881 cttcatgggg agttcttggt gctgaagagc tactaagtgc aatgaaatct aagatgagag 8941 atggagaatt ttcagattgg tcatcaatag taggagaagt taatggctat gataaaagtg 9001 ttaatgattt aattgaagaa gcaaaaaact aattaaggag ggagatggtg aagcatcata 9061 tgctcactat gccctccata aattaaaaat actacctcat gaattaatga atttatctag 9121 acaagaaaag gcgtttatat atgcttcaat agatttacac gtagaaaagg aaaagaaaga 9181 agcaaatagg atgaagagaa aaagataaaa agagaggagg taatattatg gcatcaatgg 9241 aaacaggact aatggtaatg gatggtatgg tgaatcagcc catgaggcaa ccagtaatcc 9301 aaatgcaaca aatacaatta atacagcaac aaatatcatt aacgaatgtt ttacaaataa 9361 atgttcaaaa agcagcagat gaacaagata aattaaatca aaatgtaaac aaaagtacat 9421 ctagtatgtc tgctttggcg gcaaaggcat cagagacatt taaaagcttt tttaatacgg 9481 aatcattgaa aaaaggaata gagacagtta taggtgaagc aagtaaaatg caagataaaa 9541 tgatttcagt acaaggaatg cttggagata aaggagctgg aacagcatac tttagtcatc 9601 ttcaaaaaca agctaatgaa tcaggatttt catttgatga acttaaaaat aatgcacaat 9661 catttatggg agtaactaaa aatacagaaa acttagataa actagctaat ttatcagaac 9721 gtttatcact tggtaattca ggagaaggaa tatccggagc aggtggagct attaatagta 9781 tgctatctgg agatggatct gatcttaaag ataagtttgg atttaatagt ggtgatatag 9841 gaattttaca agcaagtaag gatttagacg attttacttc aaaatttgat gtgttattaa 9901 acgaaaaagg cttaaatact tcaatgttag atgaatttaa taattcagct tcctcccaat 9961 ttgagaatat taaagaaaac tttaatagta gtttaggaga agcaggacaa ggggcattag 10021 aagcgtttgc tccagttatg gaaataataa atggaatgtt ttcaaatgga tcatttcaag 10081 tattttttga tttaatatca ataggacttg gagttttagc tacaactata tcatggattt 10141 gcgaaattgt aagaaataat tggggaataa tagaatcaat tttaatagca ataggaatat 10201 atttattagg aacaataata ccaagtgttt ttacgcttat agcacagggg ttagcagttg 10261 ctgctacatg gattattgct aatttaccga tattaatggt tattggagca atagcattgc 10321 tcatatatgc gctaatgcaa tgcggaatta caactcagca ggtatgtggt tttataggtg 10381 gaattttcat ggttatattt ggttatatat acaatcgaat tgtatttatt tggaatatat 10441 tcgctagctt agctgaattt gtagagaatg tatttaatca tccattatat tctatacaaa 10501 gattatttta taatatatgg aattatatag ttgaatttgt aggtagtgct ctagattgga 10561 ttgtggaaaa agctaagagc attccatttt taaaggattt aattggagat ttttcaatag 10621 gttcttttaa agtagatata ccagatcctc cagaagacta taaaactgtt caaagaatgg 10681 aatataagga cttaggaaat gagtttgatt ttggatatac taaagcagga aattttctat 10741 ctggtgcagg aaataaattg caagatgtta catctaaaat agataacttt aaaaataata 10801 ttaatttaga tgatattaga aataagagca acaattcatt aggaaataat tcaggtggta 10861 ttccaaatga tatgggaggc ggcagtgatg ctttaacctc tgcaatagac aatactaatt 10921 taggtaataa tgtatcagaa gggtcagagg ccattaaggg gataaatgat agtgtagaag 10981 tttcaaatga gaatttggaa ttaatgaatg atttagcaga acttgaaagt cttcaaaatt 11041 tcataacgct cactccaact gtacaagtaa ctacaggaga cataaaagaa gaagctgata 11101 taaatacaat tatctctaga atagaatcat atatggaaaa tgaaatgact aatagtgcag 11161 aggggctgta tgcgtaatga gtaaaagata taagatgcga ttaagcataa atgaaggtag 11221 agaaggattt attttgccag ttcttccaca agaaattgag ataagtgata gtggagataa 11281 taaaactcac aatgtaataa atttaggtga agtaaatgta ataaatattc ctaagttaac 11341 taaaatatca tttaaaagct atttccccaa aaataatggt ccttatgtga atgataagca 11401 tttttttaga ccacatgaat atatgaggag actaaatgaa tggcgtcaaa atgcagaaaa 11461 agtaagattt atatttatag gttcggaatt tgaaataaat gatttatttt ctattgaaaa 11521 tcttaaattt accgaaaaag gtggagaagt aggagatata tactattcaa tagagttaaa 11581 aaggtataaa ccttattatg ctaatagggc agttgtaata gaaacaaaaa atggtgtcat 11641 tgttgaaaat tataatacaa cacttagacc tgatgataaa gtaaaaatta atattcataa 11701 agtagttgaa ggtgacactt tatggcatat tgcaaaaaaa tatttgggtg atggaaatag 11761 atataaagaa atagcagaac taaataatat atcaaatcca gatttaatat atccaggaca 11821 agttattaat attccataaa ggaggttaac atgaatatag aattattaat tgatgataaa 11881 aaaagtaata tctataatct tagcaatctt ataaaacaag taacatggaa aacaaaaaga 11941 aaaggaagtc cttcaagctt agaagtaaca ttgttaacag atgaaacatt aagtgtatca 12001 aatggtgata tcataaggtt taaagttgat ggaatcaata ttttttatgg ctatgtattc 12061 aaatatagtg gtaatgaagg ggaagaaata aaactaacag cctatgatca gattaaatat 12121 ttaatgtata atgacacttt ctcagatgtt aacttgaaag caagtgatgt agttgaaaga 12181 atactttata atctaggatt gacaaaaggt attatagaag atactggtta tgtaattcct 12241 agatttaacg aaaaagataa aaaactatta gatattattt ataaagcatt ggaaaaaact 12301 ttagcttcaa ctaaaagaac ttttgtctta tatgatgatt ttggaagcgt taatcttaaa 12361 gatataaata atatgagaca ggaattaata atatccgaaa atactaattt aggtaaatat 12421 gattggagta agtcaattga agaaagttac aatgctataa agcttgttag aaaaaatgag 12481 gattcagaag aagaaaaagt atacactaag gaagataaag ataatattta caaatggggt 12541 aagcttcaat tttttaaaag tattgatgat aaagtaaatg aggctaaaat ggaagaaata 12601 ctcaaagctc atttaatatt gaaaaataaa gagaagaagt cattaaaact taaagatgtt 12661 ttaggtactg atattaaatt agaggcaaaa cttagaggag gatctggtgt gtgggttgat 12721 ataaaaagat atggaataaa ccaaatatat ttaatagaag aagtcacaca taagttttct 12781 aaagatggac acataatgga ttttgattta aaggtggtgt aaagtttggc tagtatgata 12841 gaaattataa aacaagcaag tgtaaatgca attaatgctg gaaatccttt agatatagaa 12901 tttggaacta taatagatga taatttaact gttaggatag atcagaaaag aatattacaa 12961 aaagattttt ttgttgttcc agaaagttta aatagatatg aaatagattt gacacacaat 13021 cactcagata catcatcagc tcttggcaca atagttatta gagaaggatt aaaaaaagga 13081 gacattcttg cattgttaat gattgaaaag ggaagtagat tcttaattct tgataaggtg 13141 ggaaaatatg aataatttta gtgtattgcc taaaggaggt ataataaaag atattgataa 13201 tataaaagag aaaaagcatt ctagtaaaac ttataagata aaagaaaata gaataattgg 13261 attttgtgat gagatagaag cacttgagca gacaatatat tttatattaa atacagaaag 13321 atatgattat ttaatatatc ctgatagcta tggaagtgaa ttaagaagaa ctatagaaat 13381 ggacaggggt attgcagaaa gtgagttaaa gcgtagaatt aaagaagcat taactcaaga 13441 tgatagaatt gaaaatgtag atgaatttat atttgaatat gagaaagaca gtgtattagt 13501 aaaattcact gtcttttcta tttactcaaa attatatgaa agtgtggtga tttaaatttg 13561 tttgaagtaa aagaagagga tttgttaaaa gagatgatag ataaaatccc taatgatttg 13621 gataaaagag aaggcagtag tttaatctat aatgccttag ctccagcagc acaagaaata 13681 tcaagactaa gatctgacat ggataggttt ttagaatata cttttgcatc acctaatata 13741 cctgatgaat atttagataa aagatgtgct gaacatggaa ttgaaagaaa gaaagcaaca 13801 tatgcagtaa agttaggaac tttttatgat acagaagaga agttaattga tattccattg 13861 aattctcgat tttctataga taaaaccaca tacattgcaa tagaaaaaat tgaaaaggga 13921 aaatataaaa tgcaatgtga acttataggt actaaaggaa attatctaag tgggaattta 13981 cttcctgttg aatacattga aagattagga agtggagttt taggtgaaac aatactagat 14041 ggtgttgata cagaaaacaa tgaaagtttg tttaatagat tgatggtaaa agtaagaaca 14101 ccatcaacat ctggtaataa atatgattac ttaaattggg ctttaagtgt taatggagtg 14161 ggagatgcaa aaatattttc cgaaactaat ttaaaaggtg aacatgaaag tggatgtgtg 14221 aaagttgtta tagtagattc taacaagcat aaggctagtt tgaaattaat agaagatgta 14281 tctcaatata tagaaatggt taggccaata ggggctacag ttagtgttgt tagtgcagta 14341 gaaaagacaa tcaatataac cgctgatata aatttaataa aaggatataa tttaggtgtg 14401 acagagaaag aatttgttaa attattagaa gaatacttaa aaaatataag ttttaaacaa 14461 gactatataa gtattgcgag aattggagaa atattactta atacaaatgg agtgatagat 14521 tactctaact tactaataaa taaaaatact tctaatataa aattagctga tgaagaaata 14581 gctattttag gaaatgtaag tttaggagtg atgtaattgg atataagcaa tttcaatgaa 14641 aaatttaata agattgaagg aaatatttat gttatagaag aaaaaataga gcaaattaat 14701 ggagtttatg aaggtgaact tgctcatgat aatattaata ttaaaacatt aaatgtatat 14761 acaggctcaa agctaacagg agaaaagata gaaagttata gtatttcaac accaagtttt 14821 actccatgga aaaccataat taaagtattt tcagaagtaa cacctttata tatttcttat 14881 gaaacagttg gagatcaggt agaagcagaa gatattaata aacttcaaga cacattagtc 14941 tttacacaac aaaaccttaa tgaagaaatt catagggcaa ctaaatctga gaatatatta 15001 atagataatt taaatagtga agtagtaagg tcaacacaag ttgaaaataa tatagctatg 15061 aatttaaata cagaggttaa tagatctaag aatgtagaag atgctattaa taaagagctt 15121 agcaatgaag ttaaaagagc aattaatgct gaaaaagtat taacagataa tgtgaatact 15181 acaaatagta aactgactac tgaaagagat agagctgaaa aggctgaaga aatattaacc 15241 aagagtatta ataatgaaat atctagagca aagagtattg aagatgatat taaaagcaaa 15301 cttaatgagg aatttaatag atctaaaaaa gaagaaacaa gtatagtgaa taaccttgag 15361 aatgaagtta aaagagcaat tgatgctgaa aaaatcttaa cagataattt aaatagtgaa 15421 atatataggt caaaaactaa agaaaataat atagaagaaa atattaatag ttataaaagt 15481 tctaataata ttgaaataca aaagttaaaa gaaaaagata tagattttca aaataaaaaa 15541 tcagatttat catatgtaaa ttcagaatta aataaaagat atacaaaaga tcaaacattt 15601 actagggaag aagttcttca aaagataaaa gacattatag ggactgctcc agaagcatta 15661 gacacattac aggaaatagc taaggcttta aataatgatg ctgattttgc aggtactatg 15721 actaaacagc tcactactaa agttgataaa actcaaggca aacaattaac tgatgaaaat 15781 tacacattag aagaaaaaaa caaactaagt aaaatagaaa aagaagctaa taattacgta 15841 catccagcta atcacagtgc agatattata gtagataatc ctaataaaag atttacaaat 15901 gatgctgaaa agtcaaagaa cttagaatct tataataaaa agcatgaaca tttaaataaa 15961 actacattag atagaataac ggataatcta ataaacaagt ggagtgatgc taatactcat 16021 gttaatgata atgttagaca tattactgat gaggaaagaa aactatggaa tacagtaagt 16081 aaaaaatctg acaatggtca tgttcataac tataatgaat taagcaataa accacttata 16141 ccaacaaaaa caagtgaatt aaataatgat tttggattta taactcaaaa ggatatagat 16201 acatcacaaa atcatataca ttcaaataag tctgtactag atgaaattaa taagagttta 16261 atagataatt ggaatactgt aagtaataaa gtagataaga ggcataagca ttcaatatca 16321 gaaataaata atatgccatc atctttgcca gccaatggtg gaacagcttc aagaatttat 16381 gggagtatgg cttcaaatga ttttataaga atagaaggac aaggaaagga tgataatgga 16441 agtttagaaa tagctactgc agataatgga aacgaaccta tttatgtaag gcaatatact 16501 ggaagctttg ctactatttc taggacacta acattgttag attctaatgg aaatacaatt 16561 tgtcctggaa ctttgaacgc taataatcta caagtttgtg gagcaaatgt atatacaact 16621 aatagaaaac caacggctag tgaaatagga gctatggcaa agggacctat aaagtggaat 16681 gatttaaagg gggtatagca tgtatggatt aaataattat ggaacaatta aatatgcaga 16741 aaaaaaatta aatgaagaag atataaaaaa atactttctt aatttaagta aatatgtacc 16801 ttcttttatt tcagatataa aagaaatgaa gactatctat aatgttcaag gaacagaatt 16861 aggtggtttt ttatattatt taaaagattt aattgatcaa gcatttatag aaactgctac 16921 atggggatta atttattggg aaaatgagta tggaatagaa acgaatttaa atagtagcta 16981 tgaagacaga cgagaaataa taaaggctaa aaaaaggggg agtggtacta caacaaaaga 17041 aatgattaaa aatgttgctg aaacattctc tggcggagaa gtaaatgtaa tagaagataa 17101 taaaaattat tcttttatag tgcaatttgt tggagtaaaa ggtattccta agaatatgca 17161 aggatttaaa aatatgctag aagatataaa gccagcacac cttagctata gttttaaata 17221 tacatttaca atttgggatt ttattaaaga aaaagatctt aagtggaata gtattgaaaa 17281 taaatcatgg aatgaattaa aagtttatga ataggagatg aagaaaatat gaaattaaca 17341 agtaattata gtttaaaaaa accagatggt agtgatgttg ttaatataca agattttaat 17401 gataattcag ataagattga tttagaatta aaaaaagttg attcacaatt gaaagaaaaa 17461 gcgaatctaa aagatgtgaa aatatttagt agtttagctg atataggatt aactcaaaat 17521 gatatgacta ctgattttgc tagtaatgtg ctaaagatta ttaaagcgat tggagcaaat 17581 agaagaatat ctctatatcc atatcaaact gaatcaaata ctaatttata taattcagtt 17641 aaaacgtggt gtggttttaa tactgatgcg tttcatgtaa ttatagacac atctttcaat 17701 ggtgctgaga acttacccaa taaaattgaa gtaattccta attataataa tggaaataat 17761 agagtatttt tggggtttta tgataatgaa ttaggaaatt gtagagaagt agccacaacg 17821 gaaagctttg agataaacct attaaacggt gcgagtgttt acttaacaga ctcaaattat 17881 tcaccatatt ttataagagt agggcaacta gcaacaatta caggtaatat aaaagtaagt 17941 gggatatctg acgatactgt aataatgaga ttaccacaac ctaagggaca taaatggatt 18001 aaaacattta ctaataatgg tattcctata tcattctatt tatctcctag tggtgaactg 18061 aaaatacgtg gtgcatcaag ggtagatgaa ggtgataatt tacctttaga ttttttatat 18121 cgaatataaa aggcaggtga aataaatgac tattgaagaa gtagataaat taaatataaa 18181 aaatgaagat ggtgaattta cacccaagac tatagaaaaa atagttgaag aagaaatcga 18241 tggtgaaact gtacaaacat ttgattatga aatagtacaa agtgctgaag attattataa 18301 agagtggcta aataataaaa ataatcaacc taaaaaagag ccaacagaaa atgaagtgtt 18361 gatctctaat ataatattag aaaatgcaca attaaaaaca ggattgcaag agcaacaaga 18421 attaacagct aatctattat tacaaatagc tgagttgaag ggtggtaatg caaatgtata 18481 aatggattaa aaagttttat cttatggaac tttatacaga tgaaaactta aatgtatttg 18541 taggaagtaa agatattacg gaagaagaaa aacaagagat tgtaaatagc aaagttattt 18601 cgcaatagga ataaattatg aattataaat aaaaatgtaa aggcaataaa ttaatcacct 18661 ttttaggtgt tttttattgc ctctttaatt taaaattaat cagataaaag gaggagtata 18721 tttggatgaa ataatgaaaa tggcgttaag tcaggggtta ggatatgcat tatttgtttt 18781 cttattattg tatgttctta agacaactgg tgaacgagaa aataagtatc aaagtttact 18841 tgatgcttta gctgaaaagt ttaatgttgt tgaagacata aaagaagatg tcaaagaaat 18901 taaaaataaa attgaaagtt agaaataaaa atagattaaa ttttataaat aagttgacat 18961 atcaaataac attttactta tgaatagata gcatcatata ttttaaagac agtattcatg 19021 taaataaaaa ttacttagta actatgaaag gtgaggttag atgagaggga tagatgtaag 19081 cgatcataat ggagatataa attttaataa agtaaaagaa gataatatag aagttgttta 19141 tataaaagca actgaaggaa caacgtataa agatccttac ttaaataaaa attataatga 19201 agctaaaaaa gttggtctta agacaggctt ttatcatttt ttagttggct cttctgagcc 19261 agaaactcaa gcaaaaaatt tctataataa tataaaagat aaagtgaatg atttaaaacc 19321 atgtttagat gtagaaataa gtaattttaa tgtaatggat tatgttttaa aatttataaa 19381 aaagtttgaa agtttatgtg aattaccact ttgcatatac acttcacctt attttgcgaa 19441 tgaaaaccta gattctagag ttactaaata taaatgttgg atagctcatt atgaagttga 19501 aaatcccatg aaaacaatta tatggggaga gaattatgca ggacatcaat ttactgaaaa 19561 aggtaaaata aaaggaatta atactaatgt agatataaat aaatttacag aagatatatt 19621 agtagaagaa aagaaaatag gatatgtaat aactgattat ttgccaaatg gatatagagg 19681 aaataatcag tttaagggta ttgatttaga atatgtttta agttatttta atgggattag 19741 atgttatgtt agaagcgata gtaatggtat ttggttagaa actcaagttt taccaatgag 19801 taaatgtcaa gaattaaaag ttaaattagg taattggttt tatacaataa agtaaattag 19861 attaagtata tatttcaact aaaggatata tgattataaa agatattatc ttttagttga 19921 aattttaata aaatatggta aaataatgtg attgtaaaat taaaaatatg taaagtaaaa 19981 tttgatttag gagaaatata ctatgaaaga acaatggtat gagaaagctt gggctacaat 20041 tttgttttta tttatttttt atccagtagg attatattta atgtggaaat ataggagtat 20101 aaataaaatt gcaaaaatat tgattacaat gtttgtaatt tgtttgtcat ctacatttgt 20161 tagctaaaat taaaattttt tatatgaacc taaagcataa attcacttct taaaatacta 20221 tagatataat catcataaaa cacttcattt aattcatgat gttcacgtaa aattccatct 20281 aatttgaatt tgtttagttt taataatgaa ttagaatcac tattaaaact tgcagtttga 20341 gcataaactt tattcatatt taattttcta aacaatagat ttagtataat tttaatggct 20401 tcattcatat aaccattttt tctaaattta ggtattaaat aatatccaat ctctaaactc 20461 ttatttctat aattataatc aaataatgtt atcttaccta atagttcgtt attattaata 20521 ttatataaac ctaatatgta ggtgttatca gaaattaata aagatttgta tagttctatc 20581 gtttcattta tagttttatt tagaataggc ctacaagtca ctttttcttc aatttcttta 20641 ttactccagc tatatatata aatcaattca tctaaagtaa tctcattaac atatattttt 20701 gaactattta taggtatatt aatgttaatt gatttcttaa aattatcttt actcactttt 20761 aagtttcctt tcttatacaa atagtaatat tgctcactat taaataaaca taattactta 20821 gttaatttta tgatttttca tatagtaact ttctatatgt atggttatgt aagctgtaga 20881 aaaggtgaaa gtgtaatttg ctacaataaa ttatactaca ttttatggaa aatatacaaa 20941 aaaatactta attagcattt ataattactt attttatcga ataaacttta ttacgaatat 21001 tgctaaatac gaggatatta ttaataaata tttcggcaat ttaactattt tgtaatattt 21061 atacaaacat atgtggtaaa attttatata taatattata ccccttaaaa taaggaggaa 21121 ctatgaataa gaaaattaaa aagaaaccaa caagaaaaaa gacgagatgt gacaaaaaaa 21181 agaaaacatc attattaata ttcatgggag caatttatat tattgctttt ttaatagtaa 21241 caacgccatt tgtattaatt tatggaccat atgataaaat taagaaaact tttataacaa 21301 cagttttagc aactcgtcat gcatatttag taaatgattt tatacctcaa caaacactag 21361 ataagatttt aggaaaaaat gaacttgaag aggatagtgt tccagcaaat acatcaatag 21421 atttaaacaa aatagatgtt aaaaataatt caggaaataa agtaactaaa tatgatatac 21481 atactgatag atatgatggt tatatgctag aaatagaaaa tccacataaa gttaaagtag 21541 caatgacaaa gtatttagga aaattaggac aaaaaaccag tgaaatggca gaagaacata 21601 atgcaatagc agctataaat ggaggatcat ttgtagataa gtcttcagat ggaataactt 21661 atgcaggaac aggtgggcaa ccaggtggat ttgtaatatc aagtggaaag gttgtatatc 21721 caataggaaa atgtaatgaa cattctgttg aaaatgtaat tgcatttact aaaaaaggtc 21781 aattgattgt tgggaatcat acacttgctg agttaaaaaa acttgatgta caagaagcaa 21841 tgtgttttag agaacctaat gtaataataa atggcattag gcaacataaa aaagaagatt 21901 atatagatgg aattaatcct aggacagcag ttggacaaaa agaagatgga acagtactat 21961 ttctagcttt ggatggtaga aagttatcta aaccaggagc tacaatatat gaagttcaag 22021 aaataatgag aagcagaggg gctataaatg caggtatgtt agatggggga tattcaacta 22081 cgatgtatta taaaggtgat gtaattaatt ctcctaatgc ttgggatgga gaaagaagtg 22141 ttgctacagc attttatgtt gaacagtaag ttaggagatg aaatattatg aaaattttaa 22201 agaatgtact agtatttagc tttatagctt tgctaattca acaaggaata ttcttatata 22261 ttgaaaatat atatttatca tcaaatatgg atattaaaat agaaaaatct gatgatagtg 22321 aagttcgtaa aaatgaacaa aaagaggttg aattaaaaga agatgtagat gatttaaaag 22381 tatcttctaa tggtagatat attgcaggac ttcaaaatgg aagattgaaa gtattagata 22441 gtgatgaaaa taaatataaa gatattaaaa ataatgttaa tagtaatatt gtattttaca 22501 aatggattac aaattcagat cgtataattg ctatacaaaa aataaaagaa aaaggaagaa 22561 attattttga gccaatagca tttaatgcta aaaatggaga acaaattgaa cttgcagact 22621 ttgatttaaa taaattaaga gtaagaattg aaaatagtga agataaggtc gaagatatac 22681 ctttttcaat aggtactcat agcttatata ttaaaattaa aaagagtaat gaaaaaagcg 22741 atttatatcg tgcaaacact atgaatcaat tagagaagaa aagaagtaat aaagaaatag 22801 gtaatattgt tatcccaact acagcggcta atgcaataat ggagatggga actcaagtaa 22861 caatattaga taaaccagat aatttattga tacctaatac aaaaaataca aagttactag 22921 gaacagacat aaatgataat gtttattttg cctcagaagt ggataataag gttgtaaaaa 22981 tatattatgc aatttcatcg gacaattata aggattggaa agaatttaag ctagataatc 23041 cagtaaataa agaagatata ttaattgact atagtggaaa agtttatatt aatgataatg 23101 aaaagaaaat tgcagtagaa cttacaagta aaaaaacaat taaatataaa ggtgagttaa 23161 tccaaacata ttctaaagga gttatatcaa agaatggtaa taaattaatc aaaaataata 23221 tataa //