LOCUS NC_010465:18 18953 bp DNA linear BCT 06-OCT-2011 DEFINITION Yersinia pseudotuberculosis YPIII, complete genome. ACCESSION NC_010465 SOURCE Yersinia pseudotuberculosis YPIII, complete genome. COMMENT locus start: 2428620; locus end: 2447572 FEATURES Location/Qualifiers source 1..18953 /organism="Yersinia pseudotuberculosis YPIII, complete genome." gene complement(0..1091) /gene="" /locus_tag="" /db_xref="2428620..2429711" CDS complement(0..1091) /gene="" /product="hydrolases of the alpha/beta superfamily" /translation="MKHNAFKMTSVFKTTSVFKSTLLAAVISLSSGGAMSADYKLNPF TLTYDGAITENVKGKVNIHPVTYKLNGLEISANVYTPANYDPAKKYPAVVVAHPNGGV KEQVAGLYAQRLAEQGYITITADAAYQGASGGLPRNVDKPAYRIEDIHGMADFITQYP GVDTVRLGLLGICGGGGYSLKAGQTDKRFSAIATLSMFDSGLVRRNGYQDSQLSTIQE RLKQASDARAQEAAGGEVTYVGDAKLTDEQIAKLPFDLYRQGFEYYGKTHAHPNSTFR YTASSLLDLMRFDASSNMDLIDKPLLMMAGSKADSLYMSETAFKGASNAKDKELFLID GATHIETYWQPEYVNQAIGKLAQFYGKNL" gene 1356..2048 /gene="" /locus_tag="" /db_xref="2429976..2430668" CDS 1356..2048 /gene="" /product="two component heavy metal response transcriptional regulator, winged helix family" /translation="MRLLLVEDEEKTSSYINRALSELGFTVDVAATGIDGLYLALEYD YDTIVLDVMLPGMDGYSVLEGLRASKQTPVLMLSARGSVDERVKGLRHGADDYLPKPF SLIELVARIQALLRRRPSDGVDVSQLHINDLHLDLLARRVTRAGERLELTAKEFALLS LLARHQGEILSKMMIAEQVWDMNFDSDANVVEVAIKRLRAKIDTPYPVKLLHTVRGMG YVLETRPDRQTK" gene 2060..3445 /gene="" /locus_tag="" /db_xref="2430680..2432065" CDS 2060..3445 /gene="" /product="heavy metal sensor signal transduction histidine kinase" /translation="MIKRSISGRLALMFALASILIVSALGIVLRSSLHNSLQKQMHNE LQFRESLMAPWILSRTTLDGWQTLATKFTDLAAAEGGRVQYWVLSDDPQLQVGGPAPR GVTWASLSKGFSKVPGATDESCSLFLLMSEIPAQGERPALRYVVAIDSTPYMGTLNEF TRTLIVITAIGVLFVALLGFVIARIGMRPVNKLSEQAQHLAPGNHGQRLDTLTLPDEL QKLAVAFNGVLERQEIAWRQLESFNADVAHELRTPLTNLMGQTQLGLSRKRETHELED LLESNLEELERMTSIVNDMLFLSHAQAGEHATQLTDVSLREETYKTTEYVEPSFAEKN LSIHVEGDITARIDRRLFHRSLANLLENSARHAVTGTTVKVTISRENNLASIAVANIG APIAAEHLNRLFERFYRVDSSRARSDTHHGLGLSIVRAVAIMHRGDVFASSQNGINTF GLTLAITDPYI" gene 3722..4144 /gene="" /locus_tag="" /db_xref="2432342..2432764" CDS 3722..4144 /gene="" /product="Carboxymuconolactone decarboxylase" /translation="MMKKKIQQYLLCTALTFAGSMASIAHAQDAAKNNTKQPSRAQQL MGDIAPKMAQLTDDVLYADIWERPQLSKRDRSLVTVSALVAMDRPDQLRSHLRLARQN GVTEEELVEAITQLAFYSGWPTAVTAISIAKEVFKEGK" gene 4199..4669 /gene="" /locus_tag="" /db_xref="2432819..2433289" CDS 4199..4669 /gene="" /product="Cupin 2 conserved barrel domain protein" /translation="MKVFLITLAALLLPGTQALAAAQAAVTVSPAGSQPTTIGAPESF TGTAKVDSRFKGTAPARISGGTVSFEAGARTAWHTHPLGQTLIVSSGTGWVQEWEGAA QQIKTGDVVWIPPGVKHWHGASAKESMVHIAVSESQDGNTVTWMEKVTDGQYPQ" gene 4882..5955 /gene="" /locus_tag="" /db_xref="2433502..2434575" CDS 4882..5955 /gene="" /product="hypothetical protein" /translation="LKALLKTFTTCMLVGGLISQSTFAEPTKPLVIQSQGSFAAGGAV ITTPGQFDPKKPLDPTGQTYHGDHASVFYQIPENPHKYPIVMLHGAGQSSRTWESTPD GREGFQNIFLRRGFSTYLVDQPRRGNAGRSMVEGTVKPLADEQLWFNQFRLGIWPDFF DGVQFSHDKETLNQYYRQMTPNTGPFDIDVISDAMSAVVDKSGPAILFTHSQGGGPGW FTAMKNANVKGIVAFEPGSSFVFPEGDVPPPTKNAFDTVKGESVPLEKFMALTKIPVL IIYGDNIPDKPTALPAQDSWRARLAVARQWRDVVNKHGGDVTVIHLPEIGIKGNTHFP FSDLNNVEIADQVSKFLKDKNLQ" gene 6735..7640 /gene="" /locus_tag="" /db_xref="2435355..2436260" CDS 6735..7640 /gene="" /product="hypothetical protein" /translation="MSKVTSPDSINRIKHTEVIAASPNSEESIRSLSVLKEKASEILE KENAQFFDILPILESLKKDDIIEILNDLLERKDITSNYQLLSEDHVYLSRQHNFHLLM RLIGRSPSTTLYANEFDILVINPMNTPVSIPLYQCQVCEDLSQRPSALIRLEDTVLMP GKVYGFEAYKYILDFDTEAAQDAFILIAHSEPKGWLSWVYDKNSLEPIESICTSLQAS RIQMYVRMLGAMNATQAVPVLEKLAKSTYANFVRWEAVESLSLIDPQSTLELLDYLVK NDSDAQIIEAAEQSLAINKAEESEV" gene 7646..8578 /gene="" /locus_tag="" /db_xref="2436266..2437198" CDS 7646..8578 /gene="" /product="hypothetical protein" /translation="MAVKVDVKENTLITLNEFVSFLETSGTIEKLRNSIYSSEVMSCV ATQLRALAANKAHIFSIIIEELEKTDHFQSQNYGQAQGFVLYTTPWYTIRLMLWIPPG HQASAIPFSYKVAHDHAFDLMTVGFFGPGYRTSLYEFDYNEPIQRTDGLTQLSYKGEM YLRENEVIYYFANKDVHIQHEPESLSVSLNLIINKPDASARQTVFDIESTDEGSNLCW GKPHFNSIEKIASQRSIFSALSTHGNMRSKKAIEKIAHNHKADEVRALSWVAMLRAND TVLSDVLTLEKSHYVRRVLAEINMAQGETSNAPK" gene 8565..9515 /gene="" /locus_tag="" /db_xref="2437185..2438135" CDS 8565..9515 /gene="" /product="hypothetical protein" /translation="MLLNNITPVNKSLTLQDLLGILSHSSAISNVANGIYVESEILEV GSWLSAYAANKDEIFSQIITELENPYQFQLENDIQAPSFILYSNERITIRLVMWLPLQ GKLDRTPYSYEEAHDHNFDFWTVNFFGGGYRTRLYDYDYDKVSGVNNEVVELNCYGDK ILSPNTVMFYFRSKDVHTQYPPDELSVSLNLIVRPIKSKHQYEFQIDSDALEGKIEAR IKKGRYERYAFQNVLYNGLLSLENEKSRQLVHKVSLCNHREEIRLIAYEALLKHAQKK GNVSDIKSISEQAFKDQSLYIKNKISHSIGSMPCMSPKPR" gene 9561..9704 /gene="" /locus_tag="" /db_xref="2438181..2438324" CDS 9561..9704 /gene="" /product="hypothetical protein" /translation="MTKNTATKVKSIKLVTFGKNTALAGAVPRTLSGQEAGRVLGFGC HHS" gene 9856..10535 /gene="" /locus_tag="" /db_xref="2438476..2439155" gene 10640..11299 /gene="" /locus_tag="" /db_xref="2439260..2439919" CDS 10640..11299 /gene="" /product="Methyltransferase type 12" /translation="MNKSTKIGSQIYTPFTLKLYDWWVLKMSNHFAWKCPTHDVLVPH FTEYAGNEHLDIGVGTGFYLTHLPETTHISLMDINTNSLAVASNRIGSTRVKECIQHD VFEPFPAQYHGYFDSISMFYLLHCLPGALKDKVQVIANTAMGLKTGGTLYGATILGND AGHNRLGKKLMKVYNSKGIFSNKDDTEDGLHAMLSSQFRDVAITRVGMVVLFTATGRR E" gene complement(11434..12072) /gene="" /locus_tag="" /db_xref="2440054..2440692" CDS complement(11434..12072) /gene="" /product="Ribose/galactose isomerase" /translation="MKIALMMENSQAGKNAIILKELNAVASEKAYPVFNVGMSDEQDH HLTYIHLGIMASILLNAKAVDFVVTGCGTGQGAMMSLNIHPGVVCGYCIDPADAFLFA QINNGNALSLPFAKGFGWGAELNVRYIFEKAFTGVKGEGYPLDRKEPQVRNAGILNQV KAAVVKENYLDTLRAIDPELVKTAVSGARFQQCFFENCQDKEIEAFVKQILA" gene complement(12319..14430) /gene="" /locus_tag="" /db_xref="2440939..2443050" CDS complement(12319..14430) /gene="" /product="Sel1 domain protein repeat-containing protein" /translation="MQGRDYIPCDIAEYHLLDVAELPPKDKNRALCDMRSFLREGRYG ELDKQLESALTASFLSRDAEQRYYRGWMDMENTPDLRSVISMGPEGLAQIKAWQHDCP ESNHAWLAETLYWHHCAWRYRSYGWAKKTTAAMWVCAAACNEMMVLAALQALTLEPRQ WMAAALIIPAITAFGVPAWLAVIIANEKADSLPVLGELRDYQQCYPEEMAALMSYSGL NAYAQILAPDALPPGLLRNQTEKALIGPHYWLFASLHIHPTQFYIFTDYIPFQMPRWR GLPQDMLDLIVSPACEHLSLQEKDHLRHLIWWDDFRDDLGHKVADLVEREWQFTEVKR EAEQALNANDRAQALRWLAASYYVMEDEPSAWHYLQQAVAQEPSLGGYLHHAALRLAG KFAPESRWRHNQICHNAQLMHSPQAMVLQGYCLLTGLFGFTQNEALGREWLDYALQHD PKDAWDQTGFILNELNYPDDATRLFTLGAEYGARGTASSLGSFYLYAPSETRDILRAI SYYRQVVEQNSTLLSQKVIAKYPLIDNTDPFSYEDELKRAYYSLARCYQLLSYEETDT VKTAELEGKLVASLKASVDWGNDVALPELLALLSELHTLSVTHQYLDFLLEHGNKGSI LAMTSLAKIYFNRKDKHIYNYKLSARWMYFALALAPDDEKVNEVFFSRHARNRWVTHR YVWSTSRIAAHEIPGQEHPIC" gene complement(14635..14793) /gene="" /locus_tag="" /db_xref="2443255..2443413" CDS complement(14635..14793) /gene="" /product="hypothetical protein" /translation="MTDFQLSYISLYCFLHLTFECILLFLICEVGAILIKWNYECTMV TRIIETEN" gene 15008..17170 /gene="" /locus_tag="" /db_xref="2443628..2445790" CDS 15008..17170 /gene="" /product="Sel1 domain protein repeat-containing protein" /translation="LKKKLVALLILSYPSVAYLKQPPPAVPKPITFVAKIDNIDFNKT AIDSDMKLLLADRFHFKTKTPCNKNTLSGRPESFGLTSEVYAEKIKSLLVEILSERYL FLTIDQCDRGGTPMLTNIEVCTEALCGAEFMKKESYLWLNQDLKATVKRQATSVIPMP LTFDKEKQLWKVAGWFIESSEETEELIPSKLLAFEGYTDDETFKTQKFVSTFKSYYSS GNIQHILTYNKEGKEDGKYDSYYDEKGKLAETLVFKNGLINGEYIIYHENGAIESKRH FIDSKIADGECPHYYDNGNIKENHSYLNNKLEGKYFEYFPDGKIKDERTYHAGKVVGK YTVYFESGKIRAIYNKNNKDQYHGTNEEYSPEGQLVSKSTYKEGKKLSSQTWYKNGKM RQEEIYDNEGRKNGVSREWFDNGQLNTSTSYKNDILDGDSQKWNEQGEIVSLSPYKDG KLQGEHKYYDSGKLLYTTMYKNDKKDGPDRRWSINTGKLIEEMPYVEGIRSGIKKEFN DRTGRLLTTTPYVNNEIQGTGETYNADGVSIIHCYINNKSIDSLYNPIEIRKKASQSD DNAQYELGKYHYTCQDYDRGLKWLEKSADHKNIKALFLLAQMYNEGDGVKEDQTKYFS YLLKAAQLGLSDAQVEIGYLYLVGEGVEKNLPEAYQWHIKAAEQGNVHAHYNLGWIYQ NGDGTEKNLDKAKFHFTVAAKSGMREAYEELKKLESNK" gene 17234..18952 /gene="" /locus_tag="" /db_xref="2445854..2447572" CDS 17234..18952 /gene="" /product="hypothetical protein" /translation="MKLKINFFSTLVYTATFCSGLSFAHAQTLPDVYSVVERKLENAL PLAEHPHYDAQAPYFELHREILMFSSPERANTLLKKLDFSSKEAMLSLNISADWIAGT GNPDKAMVFLSQIGLEKPSSFSAYKNYVDAWIEKKQPESALKLLMLDNSARNYYLPAV LDAYRDTPDQAVTIYKDIYGDNIIEPTNQLRMLLAIAENYRVNGDPKNTLIYTDKAQV MFIDVLKKKKNNEIHFYKDYLNLINLYSFAGNKQQALILSEQLLRAAGDKGTYYDLAL SGIMAFYHANGFTEEYNALIATSIATTDKSFSFAPKPIEEIKLIRLLNATNETGLIKE RIDKLMISPEYACYDDRYCYEYKIDSLNFLYLSKSDALADKYLNIIIEESQNQKFNPW ETVTKSIVKKLVDIGRIAEAKKLAADAEVIYLSQLKDSPPKEVERNYRDLAEMYGFAG DVVSAERILNKHVTTAQNYFITDLFIKNKQWDEARARVVKDTGLSGQNLTLLQNICAT NTPECMQHITFTLKSMLTRESITAEDASGNQQLYQLGIIYHSLGIKPTEEQQLLIQKL YDNAAA" ORIGIN 1 ttataaattt ttcccgtaga actgagccaa tttacctata gcctgattca catattccgg 61 ctgccaatag gtttcaatgt gggtcgcacc atcaatcagg aacagttcct tatcttttgc 121 gttgctagca cctttaaacg ctgtttcgct catatacagg gaatcggctt tactgcctgc 181 catcatcagt agcggcttat cgattaaatc catattgctt gacgcatcga atctcattaa 241 gtcgagcaga ctgctggcgg tgtatctgaa ggttgaattg gggtgagcat gcgttttacc 301 gtagtactca aaaccctgcc gataaaggtc aaacggcagt ttggctattt gctcatcagt 361 cagtttggca tccccaacgt aagtaacctc tccaccagca gcttcctgtg ctcgtgcatc 421 agaggcttgt tttaaacgtt cttgtattgt ggaaagttgt gagtcctgat aaccgttgcg 481 tcttaccaga ccggaatcaa acatgctcaa cgtggcaatc gcgctgaagc gcttgtcggt 541 ttgcccggct ttcaaggagt agcccccacc gccgcaaata cccagcaggc ctaaacggac 601 cgtgtccacc ccaggatatt gggtaataaa gtctgccatg ccgtgaatat cttcaatgcg 661 gtaagcgggt ttgtcgacat tgcggggcaa gccgccactc gcgccttgat acgcggcatc 721 cgcagtaatg gtgatatagc cttgttctgc caaacgctga gcatacaagc cagcgacctg 781 ctctttcacg ccaccattgg ggtgagccac caccacggcc gggtattttt tagcgggatc 841 ataattcgca ggggtatata cgttggcaga aatttccaaa ccatttagct tataagtaac 901 aggatgaata ttgactttgc cttttacgtt ttcggtaatc gcgccgtcat aagtcagtgt 961 aaatggattt aatttataat cggctgacat tgctccccca gatgaaagac tgatcactgc 1021 cgctaacaag gtagatttaa aaaccgatgt cgttttaaaa acggatgtca ttttaaaagc 1081 attgtgtttc atttaaataa ttctccctat atccaaaata aaccacggat tcccccgaca 1141 cgtctcttga tcttaatttg cgcggagttg gcttgtagat gagtctaagg cgggtaggct 1201 gacatcagca tgacggccag ataacatttc tgtcagttaa agaaatactt tcctgacaaa 1261 aatgtcagga aaatgtcagc ctggtgttgg tcatgaacag ctaagatagg tgaaatgcga 1321 tttttgttgc cctgacgggt aaagggagag acgaacatgc ggctattgtt ggtagaagat 1381 gaggagaaga catcttcgta tatcaatcgc gccctcagcg agttgggctt taccgtcgat 1441 gtagcggcca ccgggatcga cggattatat ctggctcttg agtatgatta cgatacgatt 1501 gtgctcgatg tcatgttgcc cggcatggat ggttacagcg ttctcgaagg cctacgcgcc 1561 agcaaacaaa ctccggttct gatgttatcc gcccgtggct cggttgatga acgagttaag 1621 ggcctgcgtc acggtgccga cgattatttg cctaagcctt tttcgctgat tgaactggtt 1681 gcgcgtatcc aggccttgtt gaggcggcgt cccagtgatg gtgtagatgt cagccaattg 1741 cacattaatg atctacatct cgacctgctg gcaaggcgtg tcacgcgagc cggtgaacgt 1801 cttgaactca ccgccaaaga gttcgccctg ttaagcctgt tagccagaca tcagggggaa 1861 attctgtcaa aaatgatgat tgcagagcag gtctgggaca tgaattttga cagcgatgct 1921 aatgtcgttg aggtggcgat aaaacgcctg cgggcgaaaa tagatacgcc ctacccggtc 1981 aaactgctgc atacagtgcg aggcatgggg tatgtccttg aaactcgccc cgatcgccag 2041 actaaataga gagagtgatc atgattaagc gttctatctc tgggcggctg gcgctaatgt 2101 ttgccttggc ctccatactg atagtttcgg ctctcggtat tgtactgcga agctccttgc 2161 ataattcatt gcaaaagcag atgcataacg aattgcaatt cagggagtcg ctgatggcac 2221 cgtggatcct ctcccgtacc acgctggacg gctggcaaac gttggcgacc aaattcaccg 2281 atttggccgc tgctgagggc ggccgcgtac aatactgggt cctcagtgat gacccccagc 2341 ttcaggtagg cggcccggca ccccgtggtg taacctgggc ttcgttaagc aaaggattca 2401 gcaaagtacc cggtgcgaca gacgagtcat gctccctatt tctactgatg tcggaaattc 2461 ctgcccaagg tgagcgcccc gctctgcgct atgtggtcgc tatcgattcc acgccgtata 2521 tgggtactct gaatgaattt acccgcacgc tgatcgtcat tactgcgatt ggcgtcttat 2581 tcgtggcact gctggggttc gtgattgcca gaataggtat gcgccctgtt aataaactca 2641 gcgaacaggc ccagcacctt gcgccaggaa atcacgggca gcgtctggat accttaactc 2701 tgccggatga actgcaaaaa ctggccgtcg cattcaacgg cgtgctcgaa cggcaggaaa 2761 tcgcctggcg gcaacttgaa agttttaatg ctgatgtcgc acatgaactg agaaccccgt 2821 tgaccaatct gatggggcaa acgcaattag gtctatctcg taaacgggaa acgcatgagc 2881 tcgaagattt actggagtcc aatctggaag aactcgagag aatgacctct attgttaacg 2941 atatgctgtt cctctcccat gctcaagctg gggagcacgc aacccagtta accgacgtgt 3001 ctcttcggga agagacctat aagaccacgg agtatgtaga accttcattt gccgaaaaaa 3061 atttgtctat tcatgttgag ggagatatca ctgcacgcat tgatcggcgg cttttccacc 3121 gctcactggc gaatctgcta gaaaacagcg cccgccatgc tgttactggt actaccgtga 3181 aagtgacgat ctccagagaa aataatctgg catccatcgc ggtagccaac attggagctc 3241 ccattgcggc ggaacatcta aaccgtttgt ttgagcgttt ttatcgtgtt gattcttccc 3301 gtgcacgcag tgacacacac catggactcg ggctctccat cgtcagggcg gtggcgataa 3361 tgcatcgtgg agatgtgttt gccagtagcc agaatgggat taataccttt ggtctgaccc 3421 ttgcaataac tgacccttat atatagacag tgagtccgtt gaaaaagaaa tgagtcgtta 3481 tgtgaagtct ggcctggctg agcgagggta acgtctatga cagtgtattt ttgcatacag 3541 gtttaagagg aggatctccc tcctcttctt ctttcttgct ttacgcgact gatcaatcat 3601 cgcaattctg acaaacatgt caggcaaccg tcagcctggt gacatgaagc atccggtaaa 3661 atcacgttat cgccaccgac ataatccccc ctctttaatc gtgccgataa caaaggaaat 3721 ggatgatgaa aaagaaaatt caacagtatc tgctttgcac tgctcttaca tttgccggct 3781 caatggctag cattgctcac gcgcaggatg cggcgaaaaa taacacgaag caaccgtctc 3841 gggcgcaaca attgatgggg gatatcgccc ccaagatggc gcaactcact gacgatgtcc 3901 tgtatgccga tatctgggaa cggccgcaac tctcaaaacg tgacaggagc ctggtgacgg 3961 tcagtgctct ggtggcaatg gatcgccctg accaattgcg ttctcatctg cgcctggctc 4021 gccagaacgg tgtcactgaa gaagagttgg ttgaggctat aacccaactt gccttctatt 4081 ctggatggcc aacggcagta acggcgatat ccattgcaaa agaagtattt aaagaaggga 4141 aatagttttt atcttcaatg gattaattag aatatctcac gttaaaggat tgaatcgata 4201 tgaaagtttt cctgatcaca ctggctgcgc ttttactgcc cggtacgcaa gcgcttgctg 4261 ctgcgcaggc ggcagtgacc gtcagtcctg cgggttcaca acctacgact attggtgcac 4321 cggaatcttt taccggtaca gcaaaagttg actcacggtt taaaggcacc gccccagccc 4381 gaatttccgg cggtaccgtc tcattcgaag ccggagcacg aacagcatgg cacacgcatc 4441 cccttggaca gacacttatt gtttcttctg gtaccggctg ggtacaggaa tgggagggcg 4501 ccgctcagca aatcaaaacc ggtgatgtcg tgtggatccc accgggtgtt aaacactggc 4561 atggcgcatc cgcaaaagag tcaatggtgc atattgctgt ttcagaatca caggacggta 4621 acactgtgac gtggatggaa aaagtcacag acggccagta cccacaataa taaaatgcca 4681 tttttgcatt cccgcctgaa acagaactac cccgagatat tcatgaatgg cggtttagcg 4741 aaagacattg agctcaaaca ttttattgat attagatatc cgttcatgag ttctgcctgt 4801 taacgcattc attttagcag catggtcatt cgtgaaaatc tcgctatgat tcagttgtcc 4861 gctatcacat aaggaaaaga ccttgaaagc cttactgaaa acattcacca cttgtatgtt 4921 ggttggtgga ttaatctccc aatctacatt tgctgaacca acaaaaccct tggttatcca 4981 gtctcaagga agttttgccg ccggtggggc cgtcattacg acaccagggc agtttgatcc 5041 gaaaaaacca ttggacccaa caggtcaaac atatcatggt gatcacgcct ctgtgtttta 5101 ccagatccct gagaacccac acaaatatcc cattgtgatg ttgcacggtg ccgggcagtc 5161 ttcccggaca tgggaaagca caccggatgg ccgcgagggt tttcagaaca tcttcctgcg 5221 ccgtggcttt tcgacctatc tggtcgatca accgcgtcgg ggtaatgccg ggcgcagtat 5281 ggtggaagga actgtcaaac cacttgctga tgagcaatta tggtttaacc agttccgtct 5341 gggtatatgg cccgatttct ttgatggcgt acagttctcc catgataaag agacattaaa 5401 tcagtactac cgtcagatga cccctaacac cgggcccttt gatatcgatg taatttcaga 5461 tgccatgtca gccgtagtgg ataaatctgg cccggctatt ttgtttacac actctcaggg 5521 tggcggccca ggctggttta ccgcgatgaa gaacgccaat gtaaaaggga tagtcgcgtt 5581 tgaacctggc agcagctttg tctttccgga aggcgacgtc cctcccccaa caaagaatgc 5641 ttttgatacc gtaaaagggg aatcggtgcc tctggagaag tttatggcac tgactaaaat 5701 ccctgtcctg attatctacg gcgacaatat ccctgacaaa ccaacggcct tgcctgcaca 5761 ggatagttgg cgtgcccggt tggctgttgc gcgtcaatgg cgggatgtgg tgaataaaca 5821 tggcggagac gtgacagtaa tccatttgcc ggaaattggt ataaaaggca atactcactt 5881 ccctttctct gatctgaata acgttgaaat cgccgatcag gtatcaaaat tcctgaaaga 5941 taaaaatctt cagtaataaa aaattagtgg ggtcgttgac ggctccacta ctgcttatat 6001 actcgtcata ctttaagctg catctgtgtt ggctacgctc aacaacccca ggtacttatt 6061 tatgtaagcg cctggggact tacttcgttg ccgccttcct acaacgccaa ttattttgag 6121 catatcgggc atttatccta agtgcacgct catatttata aatatgagga aattgtattt 6181 ttaactcatc cgcttttttt agacgataat attgggacct tctttaagcc aaaataggta 6241 gcacgggaaa ttccgctttc tctgctacca ctttaactag tcctccctgc tgaccagaga 6301 agcgcaacag ttatccctga atggggccta acatctgcaa ccattgcggc aacgctacca 6361 tcattcggcc attccagaat acgttctcgc tcaaactccg atgtctaatt tattcaacga 6421 cgcctgtaat attcataata ttaaaataaa tatcacaatt taatgcatta attaatatct 6481 ccttaacaaa tgatccatat ttttacgata gctataaaaa actaaccgct ttgatattga 6541 ctctaaaaac caaaatgtat aacacagtgt catgtcaagc ttcccagagt aaagtcataa 6601 tacgtatgtc atcacaacac taaaggggct ctgttaaaag acaaataagc tgagtacata 6661 ataagctgag tacattatga atagcagata cgttaagttt ctcagaaaca atgtatttat 6721 gctaaggaga aaatcatgtc gaaagttact agtcctgatt ctatcaatag aataaaacat 6781 acggaagtta ttgcagcatc tccaaactct gaagaaagca ttcgcagcct gtccgtgctt 6841 aaggaaaagg cctctgaaat attagaaaaa gagaatgcgc agttctttga tattctgcct 6901 attctggaaa gcctgaaaaa agatgatatt attgaaatat taaatgatct actggaaaga 6961 aaagacatta cttcaaatta tcaattgcta tcagaagatc atgtttactt aagtaggcaa 7021 cataattttc atctacttat gcggcttatt ggtagaagtc cgtcaacgac tttgtatgca 7081 aacgaatttg atattctggt tatcaacccc atgaatacgc cagttagtat tcctttatac 7141 cagtgccaag tttgcgaaga cctctctcaa aggccatcgg cactgataag gctcgaagat 7201 accgtattaa tgccgggtaa agtctatggc tttgaagcct ataaatatat tctcgatttt 7261 gatactgaag ccgcacagga cgcttttatc cttatcgctc actccgagcc caaaggttgg 7321 ttgtcatggg tctatgacaa gaactcactc gaacctattg aatctatttg taccagcctc 7381 caagcatcaa ggatacagat gtacgtgaga atgctcggtg ccatgaacgc gactcaagct 7441 gtgcctgttt tggaaaaact ggcaaagtct acatatgcaa actttgttcg ttgggaagcg 7501 gtcgaaagcc tctcacttat tgatcctcaa tctactctag agttactcga ctatttggtg 7561 aagaatgact ctgacgctca aataattgag gccgcagaac agagccttgc aataaataaa 7621 gcagaagagt cagaggtgta aatattatgg ctgtcaaagt ggacgtgaaa gaaaatacac 7681 tcatcacact gaatgaattt gtgtcatttc ttgaaacgag tggaactatt gaaaagctta 7741 gaaattcaat ctactcatcc gaagtaatga gttgtgttgc cactcagttg cgtgcattag 7801 cggccaataa ggcgcatatt ttttctatta tcattgaaga gttggagaaa acagaccact 7861 ttcaatcaca aaattacggg caagctcaag gatttgttct ttatacaaca ccgtggtata 7921 caatccggct aatgctgtgg atcccacccg gacatcaggc cagcgctatt cccttttctt 7981 acaaggtcgc acatgaccat gcttttgacc tgatgaccgt aggcttcttc ggccctggtt 8041 atcgcacatc actgtacgaa tttgattaca atgagcccat tcaacgtact gatggactta 8101 cccagctcag ttataaaggg gaaatgtatc tgcgagaaaa tgaagttatc tattattttg 8161 ctaataaaga tgtgcatata caacacgaac cagagtcact ttcggtttca ttaaatttaa 8221 tcattaataa accagatgcg tctgcccgac aaactgtttt cgatattgaa tctacagatg 8281 aaggtagcaa tttatgttgg ggaaaacccc actttaacag tattgaaaaa atagcttccc 8341 agcgctcaat tttttcagcg ctatcaaccc atgggaatat gagatcaaaa aaagctatcg 8401 aaaagatcgc acacaatcat aaagctgatg aagttcgcgc cctgtcttgg gtagcaatgt 8461 tacgtgcaaa tgataccgta ttaagcgatg tgctcacact agagaaaagt cattatgtca 8521 ggcgtgtact tgccgagata aacatggcgc aaggagaaac tagcaatgct cctaaataat 8581 attacgccag tgaataaatc actgacacta caagatttat taggaatttt gagtcactca 8641 tcggcaattt ccaatgtggc aaatgggatt tatgtggaaa gcgaaatcct tgaagtaggt 8701 tcatggcttt cagcctacgc ggctaataaa gatgaaattt tttcgcagat cattaccgag 8761 ttggagaacc cttatcaatt ccagctggag aatgacatac aggcaccgag ttttattctt 8821 tacagtaatg aacgcataac tattcgtctt gttatgtggc tcccattgca gggaaaatta 8881 gatcggacac cttattccta cgaagaagca catgatcata attttgactt ttggacagtg 8941 aatttttttg gaggtggcta tcgaactcgg ctctatgact atgattacga taaagttagt 9001 ggcgtaaata acgaagttgt agaacttaat tgttatggag ataagattct ttccccgaat 9061 acagttatgt tttattttcg tagtaaggat gttcatactc aatatccgcc tgatgaatta 9121 tcagtatcgc tcaatttaat agtgcgacca ataaaatcga agcatcaata cgaatttcag 9181 atagattcag atgcattgga aggaaaaata gaggcaagaa ttaaaaaggg aagatatgag 9241 cgctacgctt ttcaaaatgt gttatataac ggcctactga gtcttgaaaa tgaaaaaagt 9301 cgtcaactgg ttcacaaagt gtctctttgt aaccatcgag aagagatacg attaatcgct 9361 tatgaagctt tacttaagca cgcccaaaaa aaaggtaatg tgagtgatat aaagagcatt 9421 agtgaacaag catttaaaga ccaaagcctc tatatcaaaa ataagatttc tcacagtatt 9481 ggaagcatgc catgcatgag tccaaaaccc cgctaatata gttagcggat tactttatct 9541 caagaagata ggagtcatat tatgactaaa aatactgcga ctaaagtaaa aagcatcaaa 9601 ctcgtaacct ttggcaaaaa tacggctctg gcgggcgcag tgcctagaac attatcaggc 9661 caagaagccg gccgtgtgct tgggtttggg tgtcatcact cttaatttaa gcatttaata 9721 tactggacgt gacctagaag tagatattgg aataatttgt tccaataatc ttcacataac 9781 ttagtgactc aagccgggag tggcggtctt ctcacacccg gcttttatct aatagccaaa 9841 aatgaattga ggaagtatgt cctgtaattt taaaataata ctcaccggtg cgtcaggatt 9901 aattggttct gccattgctg atgcactgta taaatcaggt atgaatcttg ttcttgcttg 9961 taaacgttcc caaaaattac aagacagata tcttagcgat gataagtcca aaagagctta 10021 tttttggtat ggcgatctta ccaacgaaaa agcctgtcgt gaattagtgg agtatgctgt 10081 tcagcaaatg ggggggtgga tgtattgatc aattgtgccg gcgtctttaa tttttctgct 10141 ctcgaagaga tgacctatag tagaattacc gataccatca gtaccaacct tctcgcccct 10201 attcatctta cacatcttgt attaccttat attaagacca gtgcctgccc aataatcgtg 10261 aatatatcct caattgctgg tttctccagt ttgcctgaag gcgcgtgcta cgcagcatct 10321 aaatgggggc ttaatggctt tatccacagc atccgcgaag aattacgcaa aaaatcaatt 10381 cacatctgta atatatcgcc ttgtcaggtt aaaacactgt cccatcattc tgatacggca 10441 atcagaacca tagcaccgga aaatatcgct aatgcggtta ttttagtttt gtcatatgta 10501 caaaaaacgt cgtcttcaat tgacgtagtg ctgtagccat ttcccatgaa atccatatgg 10561 ttatgtgttt tttctatttg atctctaccc cataggttga tttaataagc accgtaacga 10621 aataataacg gaatattatt atgaacaaat caaccaaaat aggttcccaa atatatactc 10681 catttaccct gaagttatat gactggtggg tattgaaaat gtccaatcac tttgcttgga 10741 aatgccctac tcacgacgtt ttagtacctc atttcactga atatgccggt aatgaacatt 10801 tggacatagg cgtagggact ggcttttatc tgacacatct gcctgaaact actcatatct 10861 ctctgatgga tatcaatacc aacagccttg ctgttgccag caatcgcatt gggtcaacac 10921 gggtcaagga atgcatccag catgatgttt ttgaaccgtt cccagcccaa taccacggct 10981 attttgactc aatttcaatg ttctatctgc tgcattgcct ccctggtgcg ctaaaggata 11041 aagtgcaagt gatagccaat accgctatgg ggttaaaaac gggtggcaca ctttatggcg 11101 cgacgatatt aggcaatgat gcagggcata atcgtcttgg gaagaaattg atgaaggtgt 11161 ataactcaaa aggtattttt tctaacaaag acgatacgga agatgggctc catgccatgc 11221 tatcgtccca gttccgtgat gttgcaatta cccgtgtagg catggtcgtg ctttttaccg 11281 caacaggccg ccgcgagtaa tatattcacc atgcattgaa ttttagctat gcagtaaatg 11341 tgacacagca taaaaaactg cactgccaaa tatcagggtg ttatccaata attggggtgc 11401 agttcaataa gaaacctttt gttcgattat atcgttacgc gagtatttgt ttcacgaacg 11461 cttcaatctc tttatcctga cagttttcaa agaaacactg ctggaaacgt gcaccgctaa 11521 cggcggtttt caccaactca gggtcgatag cacgtagtgt atccagataa ttttctttca 11581 cgactgccgc tttcacttga ttcaagatac ccgcattacg tacctgtggc tctttacgat 11641 caagtggata gccttcgcct ttcacaccag tgaacgcttt ttcaaagata tagcgcacgt 11701 taagttccgc gccccagcca aagcctttag caaacggcag tgacaacgca ttaccattgt 11761 taatttgtgc aaacaggaaa gcatctgctg gatcgatgca ataaccacat acaacgcctg 11821 gatgtatatt caatgacatc atggcgccct gccctgtacc acaaccggtc accacaaaat 11881 caaccgcttt agcattcaac aaaatgctgg ccatgatgcc caggtggata taagtcagat 11941 gatgatcttg ctcatcgctc atcccaacgt tgaataccgg atacgctttt tccgaggcaa 12001 cagcattcag ctctttaagg attatcgcgt ttttacctgc ctgactgttt tccatcatca 12061 gtgcgatttt cattttgtta tctcctctta gtcaatgagc agtcgcccat tgaatgtgat 12121 agtttgacat gactgcgctg aacatagcat tttgtgaaca tcatttcaat tttaatgaaa 12181 atatgtttta ccttaatcgc atttcgcgat tgggtcagca ttcactcaag tggatatcca 12241 tacagaacgc accgatttta tgggccgatt acgtattaaa aatacccgga cagaacctcg 12301 cgattgatac tgattagggt cagcatattg gatgctcctg ccctgggatt tcatgtgcgg 12361 caatgcgtga tgtcgaccag acataacggt gagtaaccca acggttgcgc gcatggcggg 12421 aaaaaaagac ttcattaact ttttcatcat caggcgccaa cgccagtgcg aaatacatcc 12481 agcgagcgct aagcttatag ttataaatat gtttatcttt tcgattgaag taaatttttg 12541 ccagtgaagt catcgccaat atactgcctt tgttgccatg ctccagtaga aagtcaagat 12601 actgatgagt cacactcaag gtatgaagtt ctgaaagcag ggctaacaac tcgggtaaag 12661 caacatcgtt tccccagtca accgatgctt ttaatgatgc aaccaatttc ccctcaagtt 12721 cggcggtttt taccgtatca gtttcctcgt atgaaagcag ttggtaacag cgcgccagtg 12781 agtaataggc tctttttagt tcatcttcat acgagaatgg atcggtgtta tcgattagcg 12841 gatatttggc gatgactttt tggcttaaaa gcgtactgtt ttgctcaaca acctgacggt 12901 aatagctgat tgcgcgcaga atgtcccgtg tctccgatgg tgcatacaga taaaagctac 12961 ccaggcttga cgccgtgcca cgcgcaccat attcagcccc aagagtgaac agacgcgtag 13021 catcgtcagg gtaattaagt tcatttaaga tgaaaccggt ttgatcccag gcatcttttg 13081 gatcgtgctg caaagcataa tcaagccatt cacgccctaa cgcctcgttt tgtgtaaacc 13141 caaacagccc ggtcaacaaa cagtagccct gtaaaaccat tgcctgggga gaatgcataa 13201 gctgcgcatt atggcaaatc tggttatgcc gccagcgtga ttcaggggca aactttccag 13261 caagccgtaa cgcggcatga tgtaaatacc cgccaagact aggctcttgt gcaaccgctt 13321 gctgtaaata gtgccaggcg gatggttcat cttccatcac gtagtaactc gcggccagcc 13381 agcgtagtgc ctgagcgcga tcatttgcat tcaacgcctg ttccgcttcg cgtttcacct 13441 cggtaaactg ccactcacgt tcaaccagat cggcgacttt atggccgaga tcatcacgaa 13501 aatcatccca ccagatcaga tggcgtaaat ggtccttctc ctgaagactc aaatgttcac 13561 aagccggtga aacaattaag tccagcatgt cctgcggtaa accgcgccaa cggggcattt 13621 ggaacgggat gtaatcggtg aagatgtaga actgggttgg atggatatgc aagctggcaa 13681 acagccaata atgcgggcca ataagtgcct tctctgtttg attacgcagt aaacctggcg 13741 gtaacgcatc gggagccaat atctgagcat aggcattcag tcctgaataa ctcatcaagg 13801 cggccatttc ttcaggatag cactgttgat agtcacgtaa ttcgcccaga accggcaatg 13861 aatccgcctt ctcattggca ataatgacag ccagccaggc cggaacgcca aacgcggtaa 13921 tcgccgggat aatcagcgca gcggccatcc actggcgtgg ctccagtgtt aatgcttgca 13981 gggctgccag caccatcatt tcattacagg cggctgcaca tacccacatc gcagcagtgg 14041 tcttcttcgc ccagccatag ctgcgatacc gccaggcaca atgatgccag tacaacgttt 14101 cagccaacca ggcatggttc gattcagggc agtcgtgttg ccaggctttg atctgtgcca 14161 aaccttccgg ccccattgaa atgacgctac gtaaatcggg ggtattttcc atatccatcc 14221 agccacgata ataacgctgc tcggcatcac ggctaaggaa tgatgcggta agtgcacttt 14281 ccagttgttt atcaagctca ccataacgcc cttcacgaag gaaggaacgc atgtcgcata 14341 acgccctatt tttgtccttc gggggtaatt cagcaacgtc aagcagatgg tactctgcga 14401 tatcgcaggg aatgtaatcg cgtccttgca tagttctgtt tcctttcagt gatagggaaa 14461 taggtataaa aaacaggtga caatacttca gtgagattaa ccatacttcg ggataaacat 14521 ccccctaaaa aatcgatgtt aacgctgtgg gatatatctc atgattacgt gttggatatc 14581 ggcaaggcga cgtcatctat tcttattgaa gcacgaggat aaaataagat atttctcaat 14641 tttctgtctc tattatacgg gttaccatcg tacattcata attccattta attaatattg 14701 cacccacttc acaaattaaa aataataaaa tgcactcaaa agttaaatgt aaaaaacaat 14761 agagagaaat gtaacttaat tggaaatctg tcatttctac tgtaacctca agaattcatc 14821 accgccgata gattaatatt tttaatatta tcaatcacta ccacaacatc tgaaaaatta 14881 cgttttgaca ctcattaatt tacttgtaat atattagcac tattggttag aaaaatggca 14941 tttcaccctg aaattgacta taaaaaatat tatggcaatg gattgaacgt ttaaattaag 15001 gattaacatt gaaaaaaaaa ctggtggcac tcttaatact ctcttatccg tctgttgcat 15061 atctaaagca accccctccg gcagtaccta aacccattac ctttgttgct aaaattgata 15121 acattgattt taacaaaacg gccattgata gtgatatgaa attactgctg gccgatcggt 15181 tccactttaa aaccaaaacc ccctgtaaca agaatacgct ttcaggccgg ccagaatcat 15241 ttggtttaac gtcagaagta tacgcggaaa aaatcaagag tttgctcgtt gagatcttaa 15301 gtgaacgtta ccttttcctg acaatagatc aatgtgaccg cggtggcaca ccgatgctca 15361 ccaatataga agtttgcact gaagcactgt gcggtgctga attcatgaaa aaagaatctt 15421 atctttggtt aaatcaagac ttaaaggcca cggtgaaacg ccaggcgaca tcggtgatcc 15481 ctatgccatt aacctttgat aaagaaaagc agctgtggaa agtggccggg tggtttattg 15541 agtcatcaga agaaactgaa gaacttatac cgagcaaact gctggccttt gaaggttata 15601 ctgacgatga aacattcaaa acacaaaaat tcgtctctac cttcaaatcc tattactcca 15661 gtggaaatat tcaacatatt ctcacttata ataaagaggg aaaagaggat gggaaatacg 15721 actcatatta tgatgaaaaa ggaaaattag ctgagacgtt ggtatttaaa aatggcttga 15781 tcaatggtga gtatattatc taccatgaaa atggtgctat tgaaagcaaa cgacatttta 15841 ttgacagcaa aatagccgat ggagagtgcc ctcattatta cgacaatgga aacattaaag 15901 agaaccatag ctatttgaat aataaactcg aagggaaata ctttgagtat tttcctgatg 15961 gtaaaattaa agatgaaaga acctaccatg ctggcaaagt cgttggtaaa tacacagtct 16021 actttgaatc aggtaaaatt agagctattt ataataaaaa caataaagat cagtaccatg 16081 gaactaacga ggaatacagc cccgaagggc agttagtgtc taaatcaacg tataaagaag 16141 gaaaaaaact ctctagccag acttggtata aaaatggaaa aatgcgacag gaagaaatct 16201 acgataacga aggtcgcaaa aatggcgtat caagagagtg gtttgataat ggacaactta 16261 atacatcaac cagctataaa aatgacatct tagatggtga tagccagaaa tggaacgaac 16321 agggtgaaat agtatcactc tcaccgtata aagacggcaa acttcagggt gaacataaat 16381 attatgattc aggaaaacta ctttatacca caatgtataa gaacgataaa aaagatggtc 16441 cggatagacg atggagtatc aatacaggga agttaattga agaaatgccc tatgttgaag 16501 gcataagaag cggcatcaaa aaagagttta atgatcgtac cggtagactg ttaacaacca 16561 ccccttatgt gaataatgaa atacagggca ccggagaaac atataatgcc gatggtgtta 16621 gcattattca ctgctatatc aataataaaa gtattgactc gctatacaat cctattgaaa 16681 tacgcaaaaa agcctcacag agtgatgata atgcacagta tgaactgggt aagtatcatt 16741 atacttgtca agactatgat agaggtctta agtggctaga aaaatcagca gaccataaaa 16801 atattaaggc gttatttctt ttagctcaaa tgtataatga aggtgacggc gttaaagaag 16861 atcaaaccaa atatttctcc tatttactca aagcagcgca gttagggcta agtgatgctc 16921 aagtggaaat tggctatctg tatctcgtcg gtgaaggggt agaaaagaac ttaccagaag 16981 cctatcagtg gcacataaaa gctgccgaac aaggaaacgt gcacgcccat tataaccttg 17041 gttggatata tcaaaatgga gacggcaccg agaaaaattt ggataaggca aaattccact 17101 ttaccgttgc agctaaaagt gggatgagag aagcctatga agaattaaaa aaattagaat 17161 ccaacaagta aataatttta ataatggggt ctggattaat cagacctcat aaaattgatc 17221 atggataaga ttatatgaaa ctgaaaataa actttttttc aactttagtc tataccgcaa 17281 cattttgctc tggcttgagc ttcgctcatg cacagacatt gcccgatgtc tattcagtgg 17341 ttgaacgaaa actggaaaat gccctaccgc tggcggaaca cccccattat gatgctcagg 17401 ccccttattt cgaactgcac cgagaaatcc tgatgtttag ctcaccagaa cgagccaata 17461 cgctattaaa gaaacttgat ttcagttcga aagaggcaat gttatcactg aatatttctg 17521 ctgactggat tgcgggaaca ggtaatccag acaaagcaat ggtattttta tcacagattg 17581 gactcgagaa accgagctca ttctcagcat acaagaatta tgttgatgcc tggattgaaa 17641 agaaacagcc tgaatctgcg ttaaagttac ttatgctgga taacagtgca aggaactatt 17701 atcttcccgc tgttttagac gcttatagag atacgccaga tcaagcggtg actatttata 17761 aagatattta tggcgacaac ataatagaac cgaccaatca attaaggatg ctgcttgcta 17821 ttgcagaaaa ttatcgtgtc aacggtgacc ccaaaaacac ccttatttat accgataaag 17881 cacaggtaat gtttatcgac gtgctcaaaa agaagaagaa caatgaaatt catttttata 17941 aagattactt gaatttgatc aatctatatt catttgcagg taataagcaa caagcattaa 18001 tattatcaga acagctactc agggcggccg gagataaagg tacctattat gatttggcat 18061 tatccgggat catggcattt taccatgcta atggtttcac tgaagaatac aatgcattaa 18121 ttgcaaccag cattgccact acagataagt cctttagctt tgctcccaag cctatagaag 18181 aaataaagct tatccggttg ttgaatgcca ctaacgaaac cggcctaatt aaagagcgta 18241 ttgataagct gatgatctca ccagaatatg cctgttatga cgatagatat tgctatgaat 18301 ataaaataga ttcgcttaat tttctatatt taagcaaatc tgatgcatta gctgataaat 18361 atttaaacat tattattgaa gaatcacaaa atcaaaaatt caatccatgg gaaacggtaa 18421 ctaaatccat cgttaaaaaa ttagttgata ttggacgtat cgccgaagct aagaagttgg 18481 ctgcagatgc agaggttatt tatctctcac agctaaaaga ctctccgccc aaagaagtcg 18541 aaagaaatta tagggatctt gctgaaatgt atggttttgc aggcgatgtc gtcagtgctg 18601 aacgaatact taataagcat gtcaccaccg cccaaaatta ctttattacc gatctgttta 18661 taaaaaataa acagtgggat gaagccagag cgcgtgttgt gaaagatacc ggtctttctg 18721 gacaaaacct gacgttattg caaaatattt gtgctaccaa tacacctgaa tgcatgcaac 18781 atatcacgtt cacacttaaa tcaatgttaa cgcgtgaatc cattaccgca gaagatgcat 18841 cagggaatca acaactctac cagttgggga tcatctacca ctctcttggg ataaagccga 18901 ccgaggaaca acagcttctc attcaaaaat tatatgataa tgcggcggcc taa //