LOCUS NC_009376:20 31464 bp DNA linear BCT 05-SEP-2013 DEFINITION Pyrobaculum arsenaticum DSM 13514 chromosome, complete genome. ACCESSION NC_009376 SOURCE Pyrobaculum arsenaticum DSM 13514 chromosome, complete genome. COMMENT locus start: 2102536; locus end: 2133999 COMMENT n1_4mer:GRV/n1_4mer:RV = 1.734143; n0_4mer:D = 39.441685; n0_4mer:PS = 27.721606 FEATURES Location/Qualifiers source 1..31464 /organism="Pyrobaculum arsenaticum DSM 13514 chromosome, complete genome." gene 1..1698 /gene="" /locus_tag="" /db_xref="2102536..2104233" CDS 1..1698 /gene="" /product="radical SAM domain-containing protein" /translation="MRLAVVDGYTDEPAGLGVPPYLDVYARYVAGAAELAGVETVHYF TIDTLRQDWAKSLSHLAEYDVVVVIAGVTTPGKYLGGTPISLDEILDIGRVEGPVRIL GGPVAKFGYGIEGGTVAVPPSKFRRYYDVVVSGDVDLVVYRALTEGLEKAVPSETHKD FYLVDEFAVRGAKIVLQHPNYGKNLIVELETYRSCPRYVTGGCSFCTTVAYGPVITRS IEGIVKEVEALYKAGVMHFRLGRQADFYTYMAHDVGREDFPRPNPTAIERLLVGIRNA APGLRTLHIDNVNPGTVARWREESIQITKLLVEYGTPGNVAAMGIESADPRVVKINNL KVDTEEALEAVALFTKYGSARGPNGMPYLLAGINFVAGLPGETEETYRHNVEFLKEVL ARGLLVRRVNIRQLLIFPTSRLWPKARKLTSRLREHKRRFLLFKKWVREVFDREMLRR LVPQGTVLREVFTEVHYHNGTYARQVGSYPLLVYIPTRLELGRYIDVVVVDHGSRSVL ALPYPVNINVANKRVLRHLPGMTRDRLKALVSGRPFKSLDELKQKVGDGEYLNYVSF" gene complement(1722..1916) /gene="" /locus_tag="" /db_xref="2104257..2104451" CDS complement(1722..1916) /gene="" /product="hypothetical protein" /translation="VRLIYAYAGFSLGIALYLIVLTVSGLKTPDIAIGQAKINLFLFI VSAFVIFTLYVIYKLRESGS" gene complement(1945..2295) /gene="" /locus_tag="" /db_xref="2104480..2104830" CDS complement(1945..2295) /gene="" /product="peptidyl-tRNA hydrolase" /translation="MTIAVRKDLEISCGKAAAQVGHAAVECVLLAMRDVRWRKWLDKW LTEGQKKVVLAAEDAAHLYQIYETAKRLDLPTAVVVDAGLTELPPNTPTAVCVGPGPD DVVDKVTGSLRLYR" gene 2372..6148 /gene="" /locus_tag="" /db_xref="2104907..2108683" CDS 2372..6148 /gene="" /product="peptidase S8/S53 subtilisin kexin sedolisin" /translation="MRIKPILTALVITMVILYAQSLKTTGTNPAIFDTNAPVVAKLVV SDLNSFASQWKAAPTVRLMKIANRDVNVVSLSINGVQLSGRVDGNVASLYYKGPAAAL KKVVESPYVQSVYVKAMPEIPPKDFFTEVRDFVERGAGTPQPTLPLMREIIGASKVEQ LFGVNGTGVVIAIVDTGVDYGHLDLQDALAWLIKTKDNKEIIAASIAISGTTLQYKTL RGQTASVPLDQVASVEPLVLDADESQVILFQGFTASGGYLPTSGKAFNVVDGPSLYDV TASCNYAVAGLTSRSGVYKFGMTYLYIPWYGGYVSVGVVMYDPEQPGVYTAARVDINN NCNFSDDTELRYFGNRLIIDNPTAPTRSLGVAGGYFFDRGLWFDFYAKFYPGWDLSGN YLSIFYDFNGHGTACSSVAAGRGKATYNLGLLGPQKLRGIAPGAKVLGVKGLWSGMVE PGMMWAAGFDVDSNGQWYWTGQKRAHVISNSWGISTFTYDYAGFGYDFESAVVNALAA PRFLDRNYPGIVIVHAGGNGGYGFGTITSPGAAVGAITVGAATSGHFWLAIGTPYNGF RWGDIISWSLRGPTPAGYVKPDVVNVGAFGIATYPVGWGRYYYGTPEDWDTFGGTSQA TPLTAGVVALVLSAVADRVDPASVDPYLVRQFITSTAVDIGYTPFTAGHGFVNATATV IAARSYYGLPAPIAPVALIRTNSVFNPENSWDFQWRVNIPLYFGYLLNNLLTTQWTSY IQTYIPQPNIGMTSLYLSTTPGGQAVGQLVVTSTNWALSVKAEAFTLTPVYKKSTVIS IPVRALGGYFTMQQLGFDENVLKQADLVVFRMSYSFSAFDPEFNYALNTRPVLWVFGW ADLNNDGQISTNELTWLNYGYQRHTVTEVPVSKLSAKLLPNQRLVLRVDARPVAPPYP ATVPVNVEVVAYKRTPAPDVQITPTSIVLKPRQSFTFTVVVRAPPNVAPTAYERLVVL TINGTSYVVPLSYVVRASVPVNAEYVLTAGRSDSWYNVSEVRGGNDWSWRYESGDWRV YFISTPTLARGLYVDFAWSCTNTSMIVYTLTDSGFFAGYLWNQGVSYHQYLGSGIFTW TSTGGQARIVALPSASFAVPISVSGFAHTTMSASYPIRESRSFIILARTSLYGGCGTS EPIKGVVKPFIEGRDAPVLATTSPFIRVALSKPPIDYDFAVKFASVLGGGFVVPMATI SGDLTFNMYFIRTPLFVDYVALLYSSRYATWYRTGGNNFGGYPWYAVEGVSVIS" gene complement(6141..6545) /gene="" /locus_tag="" /db_xref="2108676..2109080" CDS complement(6141..6545) /gene="" /product="NUDIX hydrolase" /translation="VYIVERGDVFYLLLHGRFGWDFPHGLVHLYETDEAAAIREILEE TGLKVELIPSFKEEIRYKYSKKGRTVYREVVYFLARSREKEVKLSKEHDSYIWAAREE VLRLVSRDEIRAVLLKAWKKILETEKLVEKIS" gene complement(6612..7211) /gene="" /locus_tag="" /db_xref="2109147..2109746" CDS complement(6612..7211) /gene="" /product="hypothetical protein" /translation="VLSVAILREYGVDLCDGQALARCCLGDICADVPVDKKTAPGLYS LEEAERSPSLRTCLEVLKRQREKGLRRVEVCSEKKSDTCVKKLVGYLLARYGGPILLV GFNSRVAGELFSLTNGAVADVEGRLIPYDLVDLSEPENWIEKARVVLITPGALHLTNV VELVKKAKELGKPIVMYGAISTLYKDLGIEYFCPYGLRI" gene 7318..9063 /gene="sdhA" /locus_tag="sdhA" /db_xref="2109853..2111598" CDS 7318..9063 /gene="sdhA" /product="succinate dehydrogenase flavoprotein subunit" /translation="MEILKYDLLIIGSGIAGLRAATAAAWASGGKISIAILSKIQAMR SHSLSAEGGMSAVLYPEKTNDSLELHAYDTVKGSDFLADQDAVQVLVEYAPKEVRYLE RIGVPWTREPDGRIAQRPFGGMSIPRTTFAADKTGFFIMSTLFSETRRFDNIHVYHEH FVTKFIIENGEFRGVTAYDLKRGEFKFFYAKAGIIATGGAGRLYRFTTTAHSTTGETL AYALREGIAIKDMEFVQWHPTALVPSGILVSEAARGEGGYLINKDGERFMKKYAPQKM ELAPRDIVSRAILTECMEGRGFQHESGMCYVGLDLRHLGEEKINKRIPFIRELAHKYA GIDALSEPIPVRPAVHYTMGGIHTDTWGRVLTADGKWVRGLWAAGEAAAVSVHGANRL GSNSLSECSVWGRLTGEQAAKYVLEQPPLSSPDGKVVEIAKKEEARVFDKLLHKEVNA PMPYEVKRQLNDIMEEHFGPFRHGSAMAEGLAKLKKLRDISSYRVVDSSKVYNQNLKD ALEVDGMINLALVIGVGAYARTESRGAHYRLDYPKRDDVNWLRHTVAYLYGGEIKLTY TPVTITKWQPEERKY" gene 9065..9778 /gene="sdhB" /locus_tag="sdhB" /db_xref="2111600..2112313" CDS 9065..9778 /gene="sdhB" /product="succinate dehydrogenase iron-sulfur subunit" /translation="MKSLVVKVKRFDGSKTWWQEYKVDISSEKISVLDVLIKIKEEQD PTLAVRYSCRMAICGSCGMVINGIPRLACQTLISELGDSKIIVEPMWNHKVIKDLVVD LEPDFEKVKAVKPYIICDTKEIYEKDVEFGQRPEELEKYYNFAYCIQCGLCMAACPVV ASHERFLGPMALNAAYRWSADSRDQGWKERAKIIDREEGVWSCHLAYTCSAVCPRGVD PGFSIQLLKAALIRRTKKP" gene 9825..10253 /gene="" /locus_tag="" /db_xref="2112360..2112788" CDS 9825..10253 /gene="" /product="hypothetical protein" /translation="MKSGKGIGEWFRYVNYERAFFTVQRLSGIYLVLYLFGRVFSDAL LGWSYTESFDSTLLGRLLGALFFVFIAFHGLNGLRIALIEFGIIKGWPIRDPIKPLPA LRTSTLHKLYIAFMIIVGIVAAIYMPYLTFFGQSFHITGP" gene 10250..10585 /gene="" /locus_tag="" /db_xref="2112785..2113120" CDS 10250..10585 /gene="" /product="succinate dehydrogenase subunit D" /translation="MRESTIRLVFLLAALWVLFAIPVLFVTVLPLSVVMITNPITIYP HGFAQINYNLRYVEAAIATGWVIHGGLGVRRILAEFVKTERGVKLLNLFTVLLIAVVW ISALYALFR" gene complement(10804..11574) /gene="" /locus_tag="" /db_xref="2113339..2114109" CDS complement(10804..11574) /gene="" /product="proliferating cell nuclear antigen" /translation="MSVRALFPKGKEPRYVFEVLIGALPEAVLNFSHEGISLKALDPT KTALFELMFHATALEDYSIEEETKVGIIFTTLKDVLKRIGATEKLEIGVDKDRNRFSL YVYPKKGKDVGLVRRFSFPIVQAVEEEVPELPLSFDASFEMDTDVFDDVVAMVEEVSD WIEIRVGPDSVTFRGVGEGGKAAEAELTHDSDSVFSISADSPVSAKYSVEMLRDISRK MKSLSKRVKVELASGKPLRLSYEFTTGSFAATIAPRVD" gene complement(11637..11876) /gene="" /locus_tag="" /db_xref="2114172..2114411" CDS complement(11637..11876) /gene="" /product="hypothetical protein" /translation="VKSIIGTNVQNQVSSFCTVIWRGEKYRVLCTPSYLLSVATKIAE AERVSYFDIYKRLVASLGSEYSEARAAVSVLLSEK" gene complement(11909..12127) /gene="" /locus_tag="" /db_xref="2114444..2114662" CDS complement(11909..12127) /gene="" /product="regulatory protein ArsR" /translation="MGDSSRGLAELIINLLRERGELTSKEIAEILGVKRSSVTAVLAR LRREGVVEYLGFCFGGNRCNTKWRLKMN" gene complement(12242..12529) /gene="" /locus_tag="" /db_xref="2114777..2115064" CDS complement(12242..12529) /gene="" /product="hypothetical protein" /translation="MLLIKKTYIKKGEAVIGEYIFVKRGLFEAEAEYDIEEGVLYYLQ ICWLGRCYVWYNEEPDRAPPPLVVKRVRKIFRELSKFSVAANAALRVLASV" gene complement(12760..13536) /gene="" /locus_tag="" /db_xref="2115295..2116071" CDS complement(12760..13536) /gene="" /product="circadian clock protein KaiC" /translation="VAEYHLYYETIPTGIEGLDSVLGGGFIRGRTYLISGETGTAKTL TALTFLIQGALKYGEPGIYISVDETYEQFVEGARRFGWDIEDLRARGLIEVLVPEMDI VERIREKDPTAIAKSLVASIREYVAALNAQRLVIDPIAPLVSLDKDVQVLREYIRVLV MSIEREIGTTNIITTEIPSGSGAISRYGVEEFLATGVFIMGIGKTADGQFKRVMFIRK MRWSAVHPGVYEVEIVPKVGIIVKGQIRERLVPVTYLPTL" gene 13538..13978 /gene="" /locus_tag="" /db_xref="2116073..2116513" CDS 13538..13978 /gene="" /product="hypothetical protein" /translation="MLDTGYLYILFYLNTLTPVPVELVSERIKNIGKLRVYMLVESTA PDLSKEISDFMSEALAKPIEVKTGNVNIALTFLWSLVNRVAKHLEDAGEEVLDIEFSR GRTVIVTKRGYVINIVVRQRQNQYVAEIEGVVDVEESPFKVEDF" gene complement(14144..14830) /gene="" /locus_tag="" /db_xref="2116679..2117365" CDS complement(14144..14830) /gene="" /product="MoaD family protein" /translation="VKIRVKYFSALRDITGKTSEDLEMPDGSTLGDLINWFFKQYPKA QAFKEELLVLVNGKSLDWSYVLNGGDEVAIMPPVSGGGGVINTQLDLNKELADIIHKT AHQGAGGVVIFVGYVKGRVDQATVETLEYEAYEPHATSKLLEIEEWARRQEGVLDARI YHMVGSLKPGDHTIYVFVSAITREIAFRVARDALERVKHEVPIFKLEKRSDGEFWVLG DGKRVPRSRG" gene 15026..16300 /gene="" /locus_tag="" /db_xref="2117561..2118835" CDS 15026..16300 /gene="" /product="FAD dependent oxidoreductase" /translation="MKYDVVVVGAGPAGLAAAYKLASAGFKVLVLERGREPGAKELYG GRIYAYWLDRFLPEFRKDAPVDRWVRKERVTLLTENKALTVESAVLEKERSSFVVPLV SFVSWMAKLAQNAGAKIVTEITVDALVRDEKGRFVGIQSGSDMVQADFIIDAEGVNRL LLERAGIVKKLEPHYVAVGVKEVLKFENKKVLEERLGLDEDEGLAWAIAGYPTEYLPG GGFIYTYKDSLALGVVVYLKNWEKLKTPVYDLVEKLRLHPYIASLVKGATLQEYGGHM TPVAGINMAPPRFYYDGLLIAGDAAGFLLHTGVLIRGVDFAIASGVLAAEAIKETNSP SAEDLSVYEKKLRTSFILPQLEKFRSADKLLGDEALFKDLAVFSTEAAYRYFNIDDKH RTLLEAVREASKKTGISTLKIMINMLRAVRSL" gene 16297..16587 /gene="" /locus_tag="" /db_xref="2118832..2119122" CDS 16297..16587 /gene="" /product="4Fe-4S ferredoxin" /translation="MSLKYFTIEERLNANAWDVDVHRPHIKIKDPERCKKCEKKPCTY MCPAKCYVQQGDYIVLSTEACVECGTCRVVCPHGNIEWNYPRSGMGIWYRFT" gene 16590..17384 /gene="" /locus_tag="" /db_xref="2119125..2119919" CDS 16590..17384 /gene="" /product="electron transfer flavoprotein subunit beta" /translation="MKIVVLTKAAVPLSSAIKIDPKTGTLVREGVPLTTNVWDRDAVE FALKLKDRYGGEVIALSMAPPSGIPALESLIGMGVDRAILASDRAFAGADTWATAHVL AKTIEKYVPDYDLVVAGEETIDSTTAHIGAQTASWLGVPYVYYVYDAEVKGRTLVVRR FLEDEGIDEVYEVDMPAVISVLKGSQIPREVKLSRKLNAREYIQIVSNKELGLDPECI GLRGSPTLVAGMAPATYPPRKKVVIQGVPSEVVKKLVEILKSEGVL" gene 17387..18427 /gene="" /locus_tag="" /db_xref="2119922..2120962" CDS 17387..18427 /gene="" /product="electron transfer flavoprotein subunit alpha" /translation="MPCRLWPPINKEDYRGVWVYLEREGERLKDVGLELLGKARDLAQ KLGGVEVAGVLVAGGEELAREAIYHGADKVVIIDNPDLKIYTPAEYAEAIARVVQKYR PEIFLIGATKRGRELAAYIANTLATGITADCTALEIDPKTRDLLQIRPTFGGTQLATI RTPQRRPQMASVRPGVFPKPPRDPSRTGEIIVEKVEVAKRRTRLVSIEKRLEKDVADL PPVESSDVVVAGGRGLGTAEGFKLLIELAKLLNGTVGASLMAVRAGWAPHTRQIGQTG KTIRPKLYIAVGISGAIQHLMGITEAKMIIAINPDPHAPIMENADYAVVGDYKQIIPL LIEELKRLKNQS" ORIGIN 1 atgcggcttg ctgtagttga tggctacaca gacgagccgg cgggtcttgg agtcccgcct 61 tacctggacg tatatgccag gtatgtggcc ggagccgccg agctggcggg cgtcgagaca 121 gttcactact tcacaatcga cactctcaga caggattggg caaagagctt gagccacctc 181 gcggagtacg atgtcgtagt ggtgatcgcc ggcgtgacga ctcccggcaa atatctaggc 241 ggcactccta tatcgctaga tgaaatcctt gacatcggtc gcgttgaggg acctgtgaga 301 attctaggcg gcccagtggc gaagttcgga tacggaatag agggagggac cgtggcagtc 361 cccccctcaa agttcaggcg ttactacgac gttgtggtat caggagatgt tgacttggtg 421 gtgtacagag cactcaccga aggactagaa aaggcggtgc cttccgaaac acataaagac 481 ttctacttgg tagacgaatt tgcagtacgg ggggcaaaaa ttgtcctcca gcaccctaac 541 tacgggaaga acctaatagt agagctggag acttatcgat cttgtcctcg atatgtcacg 601 gggggttgtt ccttctgcac cacggttgcc tacgggccgg ttataactag gtcaattgag 661 ggaatagtca aggaggtaga agcactttac aaagccggag tgatgcattt tagacttgga 721 cgacaggccg acttctacac ctacatggcg cacgacgttg ggcgtgagga tttcccgaga 781 ccaaacccca ctgcaataga gagacttctc gtagggatta gaaacgcggc tcctgggctg 841 aggacccttc acatagacaa cgtaaacccc ggcaccgtgg ctaggtggag ggaggagtct 901 atccaaatca cgaagttgct ggtggagtac ggcacgcctg gaaacgtggc ggctatgggg 961 attgagagcg ccgacccccg cgtggttaaa atcaacaatc tcaaagtaga caccgaggag 1021 gcgctcgagg cggtggcttt gtttaccaaa tacggatccg ccaggggccc aaacggcatg 1081 ccgtatctgc tagccggcat aaatttcgtc gccggtctgc caggcgagac cgaggagacg 1141 taccgccaca atgtggagtt tctaaaagag gtgctggcca ggggcctgct cgtgaggcgc 1201 gttaacataa ggcaactcct gattttcccc acatcgcgcc tgtggccaaa ggcgcgtaag 1261 ctcacctcaa ggcttaggga gcacaagagg agatttctcc tgttcaagaa gtgggttagg 1321 gaggtttttg acagggagat gcttaggaga ttagtgccgc agggcacagt gcttagggaa 1381 gtctttacag aagtccacta ccacaacggc acctacgcca ggcaggtagg ctcctaccca 1441 ctcctcgtgt acatacccac caggttggaa ctaggcagat acatcgacgt ggtggtcgtc 1501 gaccacggct cgcgtagcgt cttggccctg ccatatccag tcaacataaa cgtggccaat 1561 aagcgagttc tcagacacct cccggggatg accagggata ggctaaaagc tctggttagc 1621 ggaaggccct ttaagagcct agacgagtta aagcagaagg tgggcgatgg ggagtacctc 1681 aactacgtgt cgttttgaca caaaggcata agacaagcgc ctcagctacc agattcccta 1741 agcttgtaga tgacgtagag ggtaaagatg acaaatgcag acacgatgaa taggaatagg 1801 ttaatctttg cctggcctat tgcgatgtcc ggagtcttga gacctgagac tgtgaggaca 1861 atgaggtaca gcgcaattcc cagggagaaa cctgcgtagg cgtatatcag cctcacgggc 1921 ggtgggaaaa acgcaaattt atacttatcg atacaaccta agagacccag taaccttgtc 1981 cacaacgtcg tcagggcctg gccccacgca gacggcagtt ggcgtgtttg gcgggagttc 2041 tgtaagcccc gcgtccacca ccaccgctgt gggcaagtcg agcctcttcg cagtttcgta 2101 aatctggtac aagtgggcgg cgtcctccgc cgccagcacc acctttttct gcccctcggt 2161 aagccactta tctagccact tcctccacct cacatcccgc atcgctagta atacacactc 2221 cacagctgcg tgccctacct gcgccgccgc tttcccgcaa gaaatctcta aatccttcct 2281 aacagcaatg gtcattttca tatgacctaa agtcgacatg taaaaaattt gtaaagttgc 2341 aatatttaaa aaaagttttc aactatgtgc tatgagaata aaacccatac ttacagcatt 2401 ggtaataaca atggtaatcc tttatgccca gtctctgaaa actacaggca caaacccggc 2461 gatctttgac acaaacgcgc cggtggttgc caaactcgtt gtttctgact taaactcgtt 2521 tgcatctcag tggaaggcgg ccccgactgt acgattgatg aaaatagcaa atagagatgt 2581 aaatgtcgta tcgctttcca taaacggcgt ccagttgtct ggtagagtgg atggcaatgt 2641 ggcatcgctt tactacaagg ggccagccgc ggctttgaaa aaagttgtgg aatctccata 2701 tgtccagtcc gtatacgtga aggcaatgcc ggagataccg cctaaggact tctttacgga 2761 ggtgcgcgat tttgtggaaa ggggggcggg cactccgcaa cccacgctcc cgctcatgag 2821 ggagataatc ggcgccagca aagttgaaca gctattcggc gtaaacggca ccggcgtggt 2881 gatcgccata gtggacacag gcgtcgacta cggtcaccta gacctccaag acgcactggc 2941 atggctgata aagactaagg acaacaagga gattatagcc gcctcaatag cgatctccgg 3001 caccactctc cagtacaaga cgctgagggg tcagacagcc tcggtacccc ttgatcaagt 3061 agcctcagta gagccgcttg tcctcgacgc agacgagtcg caggttattc tcttccaggg 3121 ctttacggcc tctggaggtt acttgcccac cagcggcaag gcatttaatg tagtagacgg 3181 acccagcctc tacgacgtca ccgcatcttg caactacgca gtggcgggtc tgacaagtag 3241 gagcggcgtg tataaatttg gcatgacgta cttgtacatt ccgtggtacg gcggctatgt 3301 aagtgtcggc gttgtgatgt atgacccaga acagccgggc gtctacaccg cggcccgtgt 3361 agatatcaac aacaactgca acttctctga cgacacggag ctgagatact tcggcaatag 3421 gcttattata gacaacccca cggcgcctac taggagcctc ggcgtcgccg gaggctactt 3481 cttcgaccga ggcctttggt ttgacttcta cgccaagttc taccccgggt gggacctctc 3541 cggcaactac ctcagcatct tctacgactt caacggccac ggcacggcct gtagctccgt 3601 ggccgcgggt aggggcaagg ccacgtacaa cctgggcttg ctgggtccac aaaagctgag 3661 ggggatcgcc cccggcgcca aggtgctcgg cgttaaggga ctgtggtcgg gcatggtgga 3721 gcccggcatg atgtgggctg ccggcttcga cgtcgatagc aacggccagt ggtactggac 3781 tgggcagaag agggcccacg tcattagcaa cagctggggc atctcgacgt tcacatacga 3841 ctatgccggc ttcggctacg atttcgagtc tgcagtggtc aacgccttag ccgcgccgag 3901 gttcctcgac agaaactacc cgggcattgt aatagtacat gccggcggca acggcggcta 3961 cggcttcggc accatcacaa gccccggcgc cgccgtaggg gccatcaccg taggcgccgc 4021 caccagcgga cacttctggc tagcgatcgg cactccgtat aacggcttta ggtggggcga 4081 cataatcagc tggtcgctga gggggccaac gccagccggc tacgttaagc ccgatgtagt 4141 caacgtaggc gccttcggca ttgcaaccta tccagtgggc tggggcagat actactacgg 4201 cactcccgaa gattgggata cctttggcgg cacctcgcag gcgacgccgc taacagcagg 4261 cgtagttgct cttgtgctca gcgcggtggc cgacagggtt gatcccgcct ctgtagatcc 4321 ctatctggtt aggcagttca tcacaagcac cgcggtcgac ataggctaca cgccgtttac 4381 cgcaggccac ggctttgtaa acgccacagc aaccgttatc gcggcgcgct cctactacgg 4441 cttgccggcg ccaatcgcgc ccgtggcgtt gatccgtacg aattctgtat tcaacccaga 4501 aaactcctgg gatttccagt ggagggtaaa tataccgcta tatttcggtt acttattgaa 4561 caacttattg accactcagt ggacgtctta tatacagacc tatatcccgc aacctaacat 4621 cggtatgaca agcctctacc taagcacgac gccaggcggc caagcagtgg ggcaacttgt 4681 ggtcacttcg acaaattggg cgctttctgt taaagcagag gcctttacgc taacgccggt 4741 atataagaag tctacggtaa ttagcatacc ggttagggca ctcggaggtt atttcacaat 4801 gcaacaactc ggctttgatg aaaacgtgtt gaagcaggcc gatcttgtgg tgtttaggat 4861 gtcttacagc ttctcggcat tcgacccaga gtttaactac gcacttaaca cgagacctgt 4921 tttgtgggtc ttcggctggg ccgatctcaa caacgatgga caaatctcca ctaacgagct 4981 cacgtggctg aactacggct accaacgcca tacggttact gaggtgccag tctcgaagct 5041 atctgcaaag ctcttgccta atcagaggct tgtgctaaga gtggatgcac gcccggtcgc 5101 acctccatat cccgctactg tgcctgtaaa tgttgaggtt gttgcgtaca agaggactcc 5161 ggcaccagat gtacagataa cgccgacaag catagtgctg aaaccgcgcc agagcttcac 5221 ctttacagta gttgttagag cgcctccaaa cgtcgctccc actgcctacg aaaggcttgt 5281 tgtcctcacg ataaacggca cgagctacgt agtgcctctc agctatgttg tgagagcaag 5341 cgtcccagtg aacgcggagt atgtcctaac cgccgggagg tctgacagct ggtacaacgt 5401 cagcgaggtg aggggtggca acgactggag ctggaggtac gagtctgggg actggcgcgt 5461 ctacttcatc tccactccga cacttgccag agggctttac gtggacttcg cgtggagctg 5521 taccaacacg tctatgatcg tctacacatt gacagacagc gggttctttg caggttattt 5581 atggaaccag ggtgtcagct accaccagta tctaggctcc gggatattta catggacaag 5641 caccggtggc caggctagga ttgtggctct cccctccgca tctttcgcag tgcccataag 5701 cgtaagcgga tttgcccaca caactatgtc agcctcttac cccatccgcg agagtaggag 5761 ttttatcatt ctggcgcgga cttcgctata cggcggctgt ggcaccagcg agccgatcaa 5821 gggtgtggtc aagccgttta tagagggtag agatgcgccg gttttagcca ccacgtcgcc 5881 gtttataaga gttgcgctta gcaagccgcc catagactac gacttcgccg tcaagttcgc 5941 ttctgtactc ggcggtgggt tcgtagtacc tatggcaacg atcagcggcg atttaacctt 6001 taacatgtac ttcataagga ccccgttgtt tgtagactac gtcgcattgc tctactcatc 6061 cagatacgcg acgtggtata ggactggtgg gaataacttt ggcggatatc cgtggtacgc 6121 cgttgagggg gtgtctgtaa ttagctaatt ttttctacta gcttctcggt ttctaagatt 6181 tttttccatg cctttagtaa aactgcccta atttcgtcac gggatactag ccgcagtacc 6241 tcttctctgg cggcccatat gtatgagtcg tgttcttttg agagttttac ttctttctcg 6301 cggctgcggg ctaggaagta taccacctcc ctgtatacag tacgtccctt ttttgagtat 6361 ttgtagcgta tctcctcctt gaaggatggg atcagctcca cttttaggcc agtctcttcc 6421 agtatttccc ttatggcggc ggcctcgtct gtctcgtaga ggtggacaag gccgtgtggg 6481 aagtcccagc caaatctgcc gtgtagcaac aagtagaata cgtctcctct ctctactatg 6541 tacactaccg ccccagcgga gcgctcataa aacctcacaa caagtctatc atgcgtgtta 6601 atattttttt actatatcct taaaccatac gggcagaaat actcaattcc aaggtctttg 6661 tacagggtgg aaattgcgcc gtacatcact attggctttc caagctcttt ggcttttttc 6721 acaagctcca ccacgttggt gaggtgcaga gccccaggtg ttatcaatac tacacgtgct 6781 ttttctatcc agttttctgg ctccgatagg tctacgaggt cgtaggggat gagtctcccc 6841 tcgacgtctg ccactgcgcc gtttgttaga gagaatagct ctcctgctac tctgctatta 6901 aaccctacta gaaggatggg gccaccgtat ctagctagca agtaacccac aagcttcttg 6961 acgcatgtat ctgacttctt ctcgctacaa acctctactc ttcttagacc tttttctctt 7021 tgtcttttca atacttcgag acatgtccgt agactggggc ttctctccgc ctcttcaaga 7081 ctgtagagtc ccggtgccgt ttttttgtct actggtacgt ctgcgcagat gtctccaaga 7141 caacatcttg caagtgcttg accatcgcat agatcaacgc cgtactctct tagtatcgca 7201 acagacaaca cgtccctaag gcgagatgta gttataaacc ttgacgctgt gtcttgagat 7261 acggctttgc gcgtttgtcg aaaatcaaaa tttaaacttt agcaataacg taatacaatg 7321 gaaattttga agtacgactt actaatcatt ggatccggaa tagcgggttt gcgtgcggcc 7381 acagcagccg catgggccag cggggggaaa atatccattg caattttgtc caaaatccag 7441 gcgatgcgta gtcacagcct ctcggcggag ggcggtatgt cggctgtact ttacccagaa 7501 aagacaaacg attctttaga gttgcacgcc tatgacacag ttaagggtag tgatttcttg 7561 gcagatcaag acgccgtgca ggttctggta gaatacgcgc cgaaagaggt tagatatcta 7621 gaaagaattg gtgtcccctg gacgagagag cctgatggga gaattgcaca gaggcccttc 7681 ggagggatgt ctatccctag gactactttc gcagccgaca agacaggctt ctttattatg 7741 tcaacgcttt tctctgagac ccggagattt gacaatatac atgtctacca cgagcacttt 7801 gtgacgaagt ttattattga aaatggcgag tttagggggg tcaccgccta cgatctaaag 7861 aggggggagt ttaaattctt ctacgccaag gctggcataa tagcgacggg cggagccgga 7921 aggctgtacc gcttcaccac cacggcgcac tccactactg gagagacact ggcctacgcc 7981 ctgagagagg gaatagccat taaggacatg gagttcgttc agtggcaccc cacggcactt 8041 gtgcccagtg gtattttagt cagcgaggcg gcaagggggg agggcggcta tctaataaac 8101 aaagacggcg agcggtttat gaaaaaatat gcgccacaga aaatggagct ggccccaagg 8161 gacattgtgt cccgtgctat cctcaccgag tgcatggagg ggaggggatt tcagcacgaa 8221 tctggaatgt gctacgtggg gctagatctt agacacttgg gagaggagaa gattaacaaa 8281 aggattccgt tcatacggga gctggcacat aaatacgccg gcatagacgc cttgtctgag 8341 cccatacctg tgaggccggc ggtccactac acaatgggtg ggatacacac ggatacttgg 8401 ggacgtgtgc tcaccgcaga cggcaaatgg gtgagggggc tgtgggcggc cggcgaggcg 8461 gcggctgtca gtgtccacgg agcgaatagg cttggttcca actctctgag cgagtgttct 8521 gtgtggggga gactcaccgg tgaacaagcc gctaagtacg tcctagagca accgccgctc 8581 tcctcgccgg atggtaaagt tgtggagata gccaagaagg aggaggcccg ggtgtttgac 8641 aagctcctac acaaggaggt gaacgcgcct atgccctacg aagttaaaag acagctaaac 8701 gacataatgg aggagcactt tggacctttt agacacggct cggcaatggc agaaggactt 8761 gccaaactta agaagctaag agacatctcc tcctaccggg ttgtagacag tagtaaggtc 8821 tacaatcaga atttaaaaga tgcactagag gtggatggca tgatcaactt ggctctggta 8881 ataggcgtag gcgcatatgc ccgcacggag tctaggggcg cccattatag gcttgactat 8941 ccaaagagag acgacgtcaa ctggcttaga catactgtgg cgtatctata cggcggggag 9001 ataaagctga cgtacactcc agtaactatt accaagtggc aaccagaaga gagaaagtat 9061 tgatatgaag tctctagtcg taaaggtaaa gagattcgac ggctctaaga cttggtggca 9121 ggaatacaaa gtagatattt catcagagaa aatttcagtt ctagacgtct tgataaagat 9181 aaaggaggaa caagacccga ccttggctgt gagatacagt tgccgcatgg cgatctgcgg 9241 ttcttgcggc atggttataa acggaatacc gcggctcgcc tgtcaaacct tgatatctga 9301 gcttggtgac tccaaaatta tagttgagcc tatgtggaat cacaaagtaa taaaagactt 9361 agtggtagac ctagagccag attttgaaaa agtaaaggca gtaaagccgt acattatctg 9421 tgatactaag gagatatatg aaaaagacgt cgagtttggt caaagacccg aggagcttga 9481 gaagtactac aacttcgcct attgtatcca atgtggccta tgcatggcgg catgcccagt 9541 ggtggcttca catgagagat ttttgggacc catggcgctg aacgcggcat atagatggag 9601 cgctgacagc agagatcaag ggtggaaaga gagagcaaag attattgata gggaagaggg 9661 cgtctggtcg tgccacctcg cctatacgtg tagcgccgtg tgcccccgcg gtgttgaccc 9721 cggcttctca atacagctat taaaggccgc tcttataagg cggacaaaga aaccttaagc 9781 tagaaacgaa gaaatagatt aatagacacg gcacaattag aaatatgaaa tcaggaaaag 9841 gcataggtga gtggtttaga tatgttaact atgaaagagc attctttaca gtgcaacgcc 9901 ttagcggaat atacctagtc ctttacctct ttggaagagt tttttcagat gcattactgg 9961 gttggagtta tactgaaagc tttgactcca ccctgctcgg cagattgttg ggagcgctct 10021 tttttgtatt tatagccttt catgggctta atggtcttag aattgcgctg atagaatttg 10081 ggataataaa aggctggcca ataagagatc ccataaaacc gctccccgcc ctcagaacgt 10141 cgacacttca caagctctac atagcattca tgataattgt aggaatagtg gccgcaatat 10201 acatgccgta tcttacattt ttcggacaaa gctttcacat tacgggacca tgagagagag 10261 cactattagg cttgtctttc ttctagcagc gctctgggtc ctctttgcca tacctgtact 10321 ttttgtaact gtgctaccac ttagtgtagt aatgataaca aatccaatca ccatataccc 10381 ccacggattt gctcagataa attacaatct taggtacgtc gaagccgcca tagccacggg 10441 gtgggtgata catggtggtc tgggcgtgag aagaatactg gcagagttcg ttaagacaga 10501 acgtggggtg aagttgctta atctttttac cgtattgcta attgccgtgg tctggatctc 10561 ggcgctctac gcacttttta gatagtcaga tttggtgtct ttcgtcacgg ttcagaaata 10621 ccagccaaca tcacacctct taaaaagggt ggctaatata aaaactgttt agtgaaaggt 10681 actacaacta tataatttgg gacctcttgc ctgttgagtg ccgttgcgtg tataacaaaa 10741 gaagcgactc aggggaagcc gtgaggaagg ggatgtggaa tcggtcgctt tgtagtcttt 10801 ttactagtca actctcgggg caatagtagc tgcgaaagat cctgtggtga attcatagct 10861 gagtctcagc ggcttgcctg aggctagctc taccttcaca cgttttgaaa gacttttcat 10921 ttttctgctt atatctctga gcatttctac actgtactta gcagagacgg ggctgtcggc 10981 agatatgcta aataccgaat cactatcatg cgtaagctct gcctctgcgg cttttccccc 11041 ctcgcctact cctctaaacg tcacagagtc cggccctact ctgatctcta tccagtcgga 11101 gacctcctcc accatggcta caacgtcgtc aaatacgtct gtgtccattt caaaactggc 11161 atcaaaactc agcggtagct caggaacctc ctcttcaacg gcctggacta tgggaaacga 11221 gaaacgccta actagcccaa catcttttcc cttcttggga tatacataga gagagaagcg 11281 gttcctatcc ttatctactc ctatttccag cttctcagtg gcgccaatac gtttcaacac 11341 gtcttttaac gtcgtaaaga ttatgccgac cttagtttcc tcctcaatgc tgtaatcttc 11401 tagtgcagtg gcgtggaaca ttaactcgaa aagcgcggtc ttagtaggat ccagcgcctt 11461 taaacttatg ccctcatgag aaaaattcaa gaccgcctca ggaagagctc ctataagcac 11521 ttcaaagaca taccgaggct ccttcccctt aggaaacaat gctctaacac tcatggatcc 11581 aattaccgca tgtgattaaa taatttatag tgactaaggt gtattagtcg ccaggctcac 11641 ttctcggaaa gaagcaccga cactgcagca cgcgcctctg agtactcact ccctaagctg 11701 gccactagcc gcttgtagat gtcgaaataa gatacgcgct ccgcttcagc tatctttgtg 11761 gcgacactta gtaaatagga aggggtacag agaactcggt acttctcccc tctccagatt 11821 acggtacaaa aagacgacac ttggttttgg acatttgtcc caattattga tttcacgtat 11881 gtttacctca ctggggggtt ctctgaaact aattcatttt aagcctccat ttagtgttgc 11941 acctgttgcc accgaagcaa aaaccaagat actccacaac accttccctc ctcaggcggg 12001 ctagcacggc ggtgactgag ctcctcttca cgcccagtat ttcagctatt tccttgctag 12061 ttagctctcc gcgttctctt agcaggttta taatcaattc cgccagcccc cgagaggagt 12121 cgcccatgta agctgttgcg cgttgatatt tattactttc gcgttaattt ttaaaataca 12181 ttagatcgac aagtgcaggc cgatgagcaa ggtcagagat cccgacacat gaagaccggc 12241 cttataccga ggctaatact ctcagcgccg cgttggctgc aacagagaac ttagacagtt 12301 ctctgaaaat tttgcgcacc ctcttaacaa ccagcggcgg gggagccctg tccggctcct 12361 cgttgtacca cacatagcat ctccctagcc agcatatttg caaataatag agtacgcctt 12421 cttcgatatc gtattccgcc tctgcctcaa ataggcctct tttaacaaag atgtactccc 12481 ctatcactgc ctcgcctttc tttatgtaag tcttctttat cagtagcatc cctctccgta 12541 ttaacagggc taactcctct gacacgtata cgtcgtagct gtaagctata tttccagcaa 12601 acaagctggt gaattaccag aatataacaa aatggtgccg atcaccctct gaggcgatgc 12661 cttgtcggaa ctaggcttat ataagtctgc gcctttttcg ctcagacgtg atgaagacgg 12721 gatttttaga gcggtgacag gcagaaccca gctgactggc tacagagttg gcaagtaggt 12781 gactgggaca aggcgttctc ttatttgtcc cttcacgatg atgcctacct ttggcacaat 12841 ttctacctca tacacgcccg gatgtactgc gctccagcgc attttcctta tgaacatcac 12901 tcgtttgaac tgcccatctg cggtcttgcc gattcccatt ataaaaacgc ctgtggctaa 12961 gaactcctca acgccgtatc tgctgatggc accagagccc gatgggattt cagttgtgat 13021 tatgttagta gtccctatct ctctctcgat actcataacc agaaccctga tgtactccct 13081 taaaacttgg acatccttgt ccagtgagac aagcggcgcg atgggatcta tcacgagcct 13141 ctgcgcgttt agagccgcca cgtactccct tatggatgcc acaagagact tcgcaattgc 13201 tgtcgggtcc ttttcgcgga tccgctcaac tatatccatc tcgggcacca gaacctctat 13261 cagccctctt gctcttagat cttctatatc ccagccaaag cgtctggcgc cctccacaaa 13321 ctgctcatac gtctcatcaa cggatatgta tataccgggc tccccgtact tgagcgcgcc 13381 ctgaataaga aaagtgagag cagtcaacgt cttggcggtt ccagtctccc cagagattag 13441 gtacgtcctg ccccttatga aaccgcctcc caacacgctg tctagcccct cgatccccgt 13501 ggggatagtc tcgtagtata ggtgatattc agccacaatg ctagataccg gttacctata 13561 tatactcttc tatttaaata ctcttacccc agtacctgtg gagctggtga gtgagcgcat 13621 aaagaacatc ggcaagttac gcgtctacat gcttgtcgag tccactgcgc cggatctgag 13681 caaggagatc agcgacttta tgtcagaggc cctcgcaaag ccaattgagg taaaaacagg 13741 caacgtaaac atagccctca ccttcctctg gagtttagtc aaccgcgtag ctaagcacct 13801 cgaagacgcc ggcgaggagg ttctagacat agaattcagc cggggccgga cagtaatcgt 13861 gacaaagcgc ggatatgtca tcaacatcgt ggtaagacag agacaaaacc aatacgtagc 13921 ggaaatagag ggcgtagtcg acgtagagga gtccccattc aaagtcgaag acttctagcc 13981 tggacgattg acgctcccat cagctcgcct agctccgcca ctaccttgcc cctcagtctt 14041 attgcgacat cccgtttgta gcccgacacc cttaaccgca cccccacagc acagatgcca 14101 atctactagg gagttggtat ctgagatagg attgtgggcc tacttaaccc cgacttctag 14161 gaactctctt gccgtctccg agcacccaga actctccgtc gcttctcttt tctaacttga 14221 aaatcggtac ctcatgcttt acacgctcca acgcgtctct agcaactcta aatgcgattt 14281 cgcgtgttat agcagagaca aatacgtata tggtgtggtc gccgggtttc agcgagccga 14341 ccatatgata tattctcgcg tcgagcaccc cctcctggcg ccttgcccac tcttctattt 14401 caagtagttt tgatgtggcg tgtggttcat atgcctcata ttcgagagtc tctactgtgg 14461 cttggtcaac tcttcccttt acgtacccca caaatatgac aacaccgcca gccccctggt 14521 gggctgtctt gtgtataata tcggctagct ccttgttcaa atcaagctgg gtatttatca 14581 cgcctcctcc accgcttact ggtggcataa tggctacttc gtctcccccg ttcagtacgt 14641 acgaccaatc tagagacttt ccgtttacta gtactagtag ttcctctttg aaagcttggg 14701 cttttgggta ctgcttaaag aaccagttga tgagatctcc tagtgtagat ccgtctggca 14761 tttctaagtc ttctgatgtt ttaccggtta tatctcttag tgctgagaag tactttacgc 14821 gtatcttcac gtcggttttg aatgtttaga atttttaagt aattcgggtt tgtacatatc 14881 taacactaat ttctataatg aaatagttct acctaaatta caaactatat tctttatata 14941 gtttattata taattttgct aaaagaaaat tcgattaact tcttgccgaa atttatatat 15001 atatttacta ccgagaaatt ctcgcatgaa atacgacgtc gtagtagtcg gagctggccc 15061 ggcgggcctc gcggcggcgt acaagcttgc ctctgctggt tttaaagtac ttgtcctgga 15121 aagaggtaga gagccaggcg ctaaggagtt gtacggcgga cgtatttatg cttactggct 15181 tgatagattt ctccctgaat ttcgtaaaga tgctccggtc gataggtggg ttaggaaaga 15241 aagagtgact ttgctgacag agaacaaggc tctgactgtg gagtcggcgg tattagagaa 15301 ggagaggtct agcttcgtgg tgccgttggt ttcttttgtt tcgtggatgg caaagcttgc 15361 acaaaacgca ggtgcgaaga tagtgactga gatcaccgtt gatgcgttgg tgagagatga 15421 aaaaggcaga tttgtgggca tccagtctgg ttctgacatg gtgcaagccg actttataat 15481 agacgcagag ggagttaacc gcttgcttct agaaagggct ggtattgtga aaaaactaga 15541 gcctcactac gtcgccgtgg gagttaagga ggtgttgaaa tttgaaaaca agaaggtgct 15601 ggaagagagg ctcggcctag acgaagacga ggggcttgcg tgggctattg ccggctatcc 15661 cacagaatat ctgccgggcg gcggcttcat atatacgtac aaggactctc tcgcacttgg 15721 agttgttgtt tatttgaaga actgggagaa gttgaagact ccggtatacg atctcgtgga 15781 aaaactccgc ctacacccct acatagcgtc tctcgtcaag ggggctacat tacaagagta 15841 cggggggcac atgacacctg tggcgggcat caacatggcg ccgccgaggt tttactatga 15901 tggcctactg atagcaggag acgccgcagg cttcctcctc catacaggtg tccttataag 15961 aggtgtcgac tttgccatag cttcgggagt attggccgcg gaggctataa aagagacaaa 16021 tagcccctct gccgaggatc tctctgtata cgagaaaaag cttagaacaa gctttatact 16081 gcctcagctt gaaaagttta gaagcgccga caagctactg ggcgacgagg ctctctttaa 16141 ggacctggct gtattttcca cggaggcggc gtataggtac ttcaacattg atgacaagca 16201 cagaacgcta ctagaggcgg tacgcgaggc gtcgaagaag accggaataa gtacactaaa 16261 gataatgata aatatgctaa gagcggtgag gagtctatga gcctgaaata ttttactatt 16321 gaagagagat taaacgcaaa tgcgtgggat gtcgatgtcc acaggcctca tatcaagatc 16381 aaagacccag aacgttgcaa gaagtgtgaa aagaagccat gcacatacat gtgccctgcc 16441 aagtgttatg tacaacaagg cgactacatc gtcctcagca ctgaggcttg tgttgagtgt 16501 ggcacatgcc gcgtcgtctg cccccacggt aacatagagt ggaattaccc acgttcggga 16561 atggggatct ggtatagatt tacgtaagta tgaagatcgt agttcttaca aaagccgctg 16621 ttccgctatc ctcagcgatt aaaatcgatc ccaaaacagg cacattagtg agagagggcg 16681 ttccgctgac aacaaatgtg tgggataggg acgccgtgga gtttgcgctt aaacttaagg 16741 acaggtatgg aggagaggtc attgcgcttt ctatggcgcc tccaagcgga atacctgcat 16801 tggagagtct tataggaatg ggagttgata gggctatact tgcgtcagac agggcgtttg 16861 caggcgcgga tacttgggcc accgcacatg tgcttgcgaa gacgatcgaa aagtacgttc 16921 ctgactacga cctagtggtg gctggtgagg agactattga cagcaccact gcgcacatag 16981 gggcgcagac agctagttgg ctgggggtgc cgtatgttta ttatgtatat gacgcggagg 17041 taaaggggag gacacttgtg gtaaggcgtt ttctcgaaga cgagggcatc gacgaggttt 17101 atgaggtaga tatgcctgca gttatttcgg tattaaaagg ctcgcagata cctagagagg 17161 tgaagctgag ccgcaagctt aacgcaaggg agtatataca gattgtcagc aataaggagc 17221 tagggcttga tccagagtgt ataggactta gagggagccc gacattggtt gccgggatgg 17281 cgccggctac gtatccaccg cgcaagaaag tggtgataca gggagtgccc agtgaggttg 17341 tgaaaaaact agtcgaaata ttaaagtctg agggggtgtt atagctatgc cgtgcagact 17401 ctggcctcca ataaataaag aggattatag aggagtttgg gtatacctag aaagggaggg 17461 agagaggctg aaggatgtgg gccttgagct gttgggcaag gccagggacc tggcccaaaa 17521 attgggcggc gttgaggtgg ctggggtgct cgttgccggt ggcgaggaat tggcacgtga 17581 ggcaatatac cacggcgcgg acaaggtagt aataatagat aacccggatc tcaagatcta 17641 tactcctgcg gagtacgccg aggccatagc tagagtagtc cagaaatata ggcctgaaat 17701 attcctaata ggggctacta agcgtggcag agagctcgct gcgtatattg caaacacgct 17761 ggccacgggc attacggctg actgcacggc cctggaaatc gacccgaaaa cccgcgactt 17821 gttgcagata cgcccaacat tcggggggac ccaactggct acaataagaa ccccgcagag 17881 gcgtccccaa atggcgagtg tgagaccagg cgtcttcccc aagccgccaa gagatccgag 17941 caggaccggc gaaatcatag tagagaaggt agaagtcgcg aagaggagga cgcgcctagt 18001 atctatagag aagcgtctgg agaaagacgt agcagatctg ccaccagtag agtcctcaga 18061 cgtagttgtg gcggggggca gggggcttgg caccgctgag gggtttaagc tactgataga 18121 attagctaag ttgctaaacg gaacagtggg cgcctcgctc atggcagtac gtgccggctg 18181 ggccccccac acgcggcaaa taggccagac aggcaagaca attaggccta agctttacat 18241 cgcagtgggg ataagcggcg ccatacaaca cctgatgggg ataacagagg cgaagatgat 18301 aattgccata aaccctgatc cccacgcccc gattatggaa aacgcagact acgccgtcgt 18361 gggcgactac aagcagatta ttcccctgct catcgaggaa ttaaagaggc ttaagaatca 18421 gtcgtaatac cagtcttcac gagtcagcga tcggggtcgt cctcacccgt ctatacataa 18481 ctgtgtctat ataagtacct aggtggcatg ttttccgtgg gcttatcgtg tcttaagttt 18541 ttaaatcccc cactttagta ggctgtgtcg tctatcttcg gcgaacagct ccctaaaggc 18601 acacgtgtgg agtatatagg cgacgtgccc atcgttgagg agtgcccgcg cgatgtcaaa 18661 actcttaacg gcgagcctgt gctcctcttc gggaagtgga gctacgagga cgttgttatc 18721 agagacccag gtctgaggag atatatctgc ctaaggcctg tggtgcttcc tcatacggag 18781 gggagatacc agaagaagcg atttggcaag gctaggatac ctattgtgga gcggctgata 18841 aacttaatga tgcgccccgg gagaaacgcc ggaaagaaac acaaggccta caacatcgtg 18901 aagagggctt ttgacctcgt gtactacaaa acaggtaaga acccgctcca agtgtttata 18961 gacgctatta taaacacggc gcctagagaa gaggttacca ggattatcat gggcggcatt 19021 gcctacgccg tatctgttga cgtgtcgccc cagaggcggc tcgacttagc tctccgctgg 19081 atagcagagg gggctagggc atgctccttt aataacccaa agcctataga ggagtgcttg 19141 gcggatgagc tagtcgccgc cgcggctaat gaccccaaga gctacgccgt gagaaagcgg 19201 gaagaactag aacgcatagc agcggcgtcg cgctaatagt ttttaacaag tcccaatttc 19261 gatacatggc tgagcttttc tggtttgaga agtataggcc gaggtctttt gatgaggtgg 19321 tggatcttga ggaggttaag gctcggctta gggagtttgt gaggggtggg aatatgccgc 19381 atctgctttt ctacggccct cctggcactg ggaagactac catggcgctt gtgttggcta 19441 gggagttgta tggggagtat tggcgggaga atacgctgga gctaaacgcc tcagacgaga 19501 gggggataaa cgtaattagg gagagggtga aggaattcgc caggacagcg cctgtgggca 19561 aggcgccgtt taaactcgta atactagacg aggcagacaa catgacctca gacgcccaac 19621 aagcactacg cagaataatg gaaatgtacg cccaaaacac aagattcata ctactagcaa 19681 actacgtgtc gcgtattatt gatcccataa tatccaggtg cgcggtgttt aggttttccc 19741 caatgccccg tagcctaatg gctgagaggc ttcgccacat tgctaagagt gaggggattg 19801 agttaagaga tgatgccata gatctgatat acgaggtatc agagggggac atgcgtaagg 19861 ctataaatct gctacaagtg gcggcggcta ctagcaaggt tgtcgacgca aacgccgtgg 19921 cgtcggccac cacgatgatt aggccggcgg atgtcgtaga gcttttcaat ttagcattca 19981 acggcgatgt tacgaaggcc agggaaaagc taagagaatt gatgtatgta aagggaattg 20041 ctggaatcga cttcataaga gcattccaga gagagctcat tcgtatgccc ctcgacgatg 20101 aggttaaagc ggagatagcc gagcttttgg ccgaagtcga ttacagatta acgcaaggct 20161 cagatgagga actgcagttg ttgtatcttc tatctaaact gggcgccata gggaagagag 20221 ctagacagac gccgcctcct tcgaagagga ggtaaatggc cctgccgtgg gttgagaagt 20281 ataggccgaa gtcgtttgca gatgtagtag accaagagga ggctaaatac gtcttggcat 20341 cgtggatctg cgccagattt agggcaccta aagacttctg taccaggtgg gcaaagaaaa 20401 aagacaagga gattttagac gcgagggctg tcctccttgc ggggccgcct ggggttggca 20461 aaaccacact gatccatgcc cttgcccgag agattgggta tgagcttatt gagctcaatg 20521 ctagcgatgt cagaactgcg gagagactaa aggaggtagt tggtagaggg ctgagagagg 20581 ggtcgctatt cggctatggg ggtaaaattg ttctatttga cgaagtagac gggcttcatg 20641 taaaagaaga tgctggggga ttagaggcaa ttatcgagat catagagaat tcaaaagttc 20701 ccatagtcat gacagccaat aatccctacg accccaggtt taggcctctg agagatatat 20761 ctctcgtggt caacctgaag cgcctctccg aggaggaggt tgtggaggtt ttgaggagga 20821 tttgcacaag tgagggcgcc aagtgtgaag aggaggcgtt gagaagtatt gctaagtcgt 20881 ctctggggga tttgcgggcg gctataaacg acttgcagat gtacctctct ggcgggagga 20941 agacgttgac tgtagacgat attaagaggg taggagagcg gaacccgcaa ctatctatgt 21001 ttgaaatact ggaccgcgta tatagggccc gttggtttga tgaagcgcgg gcaatttcgt 21061 ttaacccctc ttttgactgg gagcagtact tcatctgggc tacagagact attcccgtcg 21121 tatataaaga gatagagact atgtctgttg cctatgatag gctcagcaaa gcggatatgt 21181 tcattgggcg tataaagcgt acgcaggagt gggagctctt accatatgcc ctcgagcttg 21241 ccctcggcgg ggtttcccag attaagagca aacccaggtt gcctcccttt ataaaatatg 21301 gatttcctca acggcttctc atactcgcca agtcgagaga ggctaggaaa aggagagacg 21361 tcctcgtgga atatctggca cagaatttgc acgtatctag gtcttacgtg aagtccgaga 21421 taatctacgt attaggggtg ttggccaaga gcgattccaa aattgtagaa aggttaagca 21481 aggctcttgg gatcaacgcc atagatatca aaacgctctt gtaacgtgaa tagaaaatac 21541 attattgttc ggactattcc gaagaaggag ggacaagtag ctagggatct atgtgattgt 21601 atctatttcc atgatagcga ggttatgtgc gtcccagtgg ctgttggcag agtttatgtg 21661 tatacattag taggcgctct ccaaaactgc ttagcaatgg actatttcaa aaagctggtg 21721 agggggtttg aggtatacga cgaggtgtca cactacgaac cgtctaggtg cgatgactgt 21781 atcgtcgtaa agattggcga agtgtatttc gtacgtaggg ttggcaaaaa cttttaggat 21841 acgcattcat ctcttttcag atgtaagttg aaagtattta tattgagtca gtgatttccg 21901 catggccatt gtagttgatg aagccgtgtt ttcacccagc tacgtccctg ataagttacc 21961 gcatagagat gaacaactgc ggcagttgca ccttctgctg tctggatggc ttcagagccc 22021 tggccaacac tatcccagag taaccctagt agggaggcca ggcactggta aaactgtcac 22081 aatacgtaaa ttatgggaaa tgtataaaga gcgatcaaag gctaagttta tttatattaa 22141 tggatttata tttagaaatt ttactgcaat tataaatgaa attgccagat ctttaagtat 22201 cccgttcccg cgtcgaggtt taagcagaga cgagtttttg gcgcttctta tagaacacct 22261 acgtgagcgc gatctctacg cctttatggt ttttgacgac gcctttaacg tatcgccaga 22321 tatcctctca acttttatta gactggggca agaggttgac aaactaggcg catttagggt 22381 agccctggct gttgtgggtc acagcgacac gttgttaaac aaccttgacc cctccacacg 22441 tggaataatg ggcaagtatg tgatacgatt taacccttac accaaggacc agattttcga 22501 catattacta gacagggcga gaatggggct tgcagagggt tcctacagcg aagaaatact 22561 gcagatgata tcggacataa ctggggccca gagccccctt gatgcccaca aaggcgatgc 22621 tagactggca atagatatcc tctacagatc agcctatatc gcccaacaaa gcgggcggag 22681 acagataatg cctgaagatg tgagaaaagc ttctaaagag gtcttgttcg gagtgtcgga 22741 agaagtgctg ataggcctcc cgctccacga gaagttgctc ctacttgcca ttgtcaggac 22801 acttaaaacg ttgcacaccc cttatgtcac atttggagag gcagaagaga cctataaaat 22861 gatctgtgaa gagcatggcg aaaagccaag ggtgcacagc cagttgtgga cttatcttaa 22921 cgatctcaaa gaaaagggca taatcgagac tcgtcaaaat agaaagggtg agggggtacg 22981 tgggcggact acactcatct caataggaac cgagcccctt gacacactgg aatctgtgct 23041 gataaagata ataagggagg agttaaaatg atagaggaag cactgagggc cccgcttaga 23101 atacgtattt tactagctct ctgggagcat ggcgagatta acgcgacgga gctagcacat 23161 attttaggaa ctaactacgc ccaacttgct acgcatttaa aagatcttat caactatggc 23221 ctagtagagg agaggcgggt aggccgtgtg agattagtaa aggtgaggaa agatgatgta 23281 gtaatttctc taattaaagc tttaatagta gctaatgaaa aaattaaact aaatcaaaaa 23341 atattaaata aaacaaatag ttaatcctaa acatttcaca tacatatgca acatatttat 23401 taacgactgc tacagtgggc gtgggcgccc gtttcgagaa actagttatg gatctactcc 23461 ccgccctagg cttggcacca aagacgacac gcctcaaaat ttttagagaa ggcgttgagg 23521 taggggaagt tgacatagtc gccatagatg aaaagggaga tacctacgcc atagaggtga 23581 aggctgggaa agttgatatc agtggcgtga ggcaggctta tgtaaacgcc atgctgatgg 23641 gagccaaacc gttagtcata gcaaggggct acgcagacga gggggcgcgg caactcgcca 23701 aagaacttgg cgtagaggta gtgctattgc ccgactacat attcctctca ctagacgatc 23761 tatacactgc attcgcgagc ggactagcca gattcttcaa agcagtattg tcactatata 23821 caaatctata ccaatatctt gattacatca aagaatgcca agatatggaa tgtatttgta 23881 aaaaaataag ttgtaaggaa ttatttaaaa aactaccaaa agaagcacgt aatattgaaa 23941 tgatatcact agtcctagag ctacacaacg caatgccaat gatatgtgaa gaggtcgacc 24001 agtgtatcag atttttaaaa tctacaaata agccttgtgg atcccagagt agagaaaata 24061 cgccgtgaat ttaggcctaa ggtgaagcct attgaatgga ggggcgacaa gctggtcctc 24121 cttgatcaga ggatgctacc atttgagaca aggtatgtag aagctaggac tgtagaagat 24181 gtcgcggcag ccatccgcga tatggtcgta agaggggcgc ccgctattgg cataacagcc 24241 gctttcggca tggtgatagc gttaagcgaa aaacctattg acaacataga cgatgcccta 24301 aagactttgt cattggctag agacatcctt tctaaaacta ggccaaccgc cgtcaatcta 24361 ttctgggccc ttgataggat gcacaacaag gctcttagcc tagcctcggc tacgtcatca 24421 gttagagaac ttagagaggg actagaggcg gaggctaaga aaatattcga ggaagagcta 24481 gaggcggaga ttaggatagg tctatacggc gcggagctac tagaagctgg agatactgtt 24541 ctgacaatat gcaatgccgg tggtcttgcc acaggcacgg gcttaggcac agcaaccgcc 24601 ccaatttacg ttgctaaaat gttgggaaaa gacatttcgg taatagcacc tgagacgaga 24661 ccgtggcaac aaggcgcacg actcacagtc tacgagcttg ttaacaatgg cataaggact 24721 acgttaatag cggataccgc cttaggactt gtgatgtata agcggatggt tgacatagtt 24781 atggttggcg ctgaccgtat tttgctcgac gggcacgttt ttaacaaaat aggcacactg 24841 aacgaggcca tactcgccca cgagttcggt atacctttct atgtactagc accaaccagc 24901 acaatagacc caaaaagtag cgtagacagc gtaaaaatag aagaacgcga cccagacgag 24961 gtgcgcacgg ttagaacaag ccagggaaaa gtatatgtaa cactgaagga tatccaagtc 25021 tacaaccccg tattcgacgt aactcctcct aaatacataa cgggaataat tactgaaaaa 25081 ggagttgcga cacaacctct ctcggtaaac ctaaggaaac tgttgaaaaa catatagata 25141 agatgtataa tatctgcgcc atcaaacttt taaacacaaa tttcataaaa aacatgaata 25201 gatgctaaat tttaaaaata aaactcttcg catcgacaat gcgcctcgaa gctgctgaaa 25261 aaaagctcat tgaggctcta gtagtgttgc tactaaacgc gcggggaaaa atcgtcagta 25321 tcaaggcgac ctccctagca aaaatagcag gtctaggtga aaatcacgga gcaatactaa 25381 aagccgcgag acttcttcaa aaactttcca cgtataaatt cgtaagaata gccccagaca 25441 gaaggggaaa caagacgtat agatatgtcg taaaagctga tgacgagctg tggaaactgg 25501 tccgtaaaga cccagaaaaa gcgagagaag tgcttatgaa aataatttcc aagtaatgta 25561 ttatggaagt atagaaatag ataacttact atataaacat ttcttggaat atttatctga 25621 ctcggaaata gaatcgatgc tacgttctgt cctaacacca ccgcaacgct actacataag 25681 agttaacacg acaaagatta caccaaacga gctcataaaa agacttaacc tccgcggcat 25741 ctcagcctat aaagacgaag tctttgaaga cgccgtatgg ttccccgtag aagggccctt 25801 taagataccc tctgctaaaa agattgtagt tgttgacaaa aaagcagcag aaagtattat 25861 gttgggagct gatttatatg gacctgccat aataaaaacc gaccccgtaa aaagcggcga 25921 ggaggtaaat atagtgtcgg ataatggagt actagtggca tatgggaagg ctgtaatgaa 25981 cagcgacgag gcgctcagaa gtagaagggg gctttttgta caggttgaaa aatctctata 26041 caaggccccg aagcttagga atttgccgga atatgccgag gggcttttct acagccagag 26101 cctacctgct atagctgtgg gccacatagc gcgaaaattc gcacaacgga gcgtagtaga 26161 ccttaacgcg gcccccggcg gcaaagccac ccacctggcg caatacggaa ttcacgtgat 26221 tgctgtagat agatcctcgc caaaaattag caaattgaaa tacgaggtag aaagactcgg 26281 actcaactcg gtcgacgttt tgctacacga tagtaggtat ctagataggg atttccccaa 26341 attaaaagcg gatgttgcgc tggtagatcc accttgcacc gacctaggag tgagacctaa 26401 gatataccaa aaagtgacgt acagcacggc caagacattg tccaagtacc aggttcagtt 26461 tttaaaaacc gcgttaaagc tcgccgacta cgtaatttat tcaacgtgca caaccacagc 26521 aatagaaaac gaagaagtga ttaagaagtc cggagcggaa atagtagacc cggaaataag 26581 cataggcgcc ccaggttggg aatgtgcaga gtgtagaaga ttcttgccgc acatacataa 26641 caccccgggc ttcttcatcg cggttctaaa ggctaagaaa gcgccttgat agtcctcgac 26701 acatatgagt cgcatagttt cttgtaggcg cagtagatac aagcaacggg gctttcccct 26761 cttaatcttt tttctataac tttgcagata tttttaatat aaaactgagg gaaacactct 26821 ttacaaacaa ataaatcttt atgtatatat gatatattct taaaatttac ttcccgttta 26881 cacacagcac attgaggcat ttgagatata tgccacaaat ttataagcgt aaacattacg 26941 taatattgtg ttccagccat acaccctaga agaaggcaga tatctagtca agctagctag 27001 gtctgttgta gaggcttatc taacacacgg caaaatcgtg attccagaaa accccccgcc 27061 gagacttata aacgacaact acggcgtatt taccacaata gagacagtcc agggagagaa 27121 atttgaacta agaggatgca taggctatcc cgaggggtat aaaaacacgc tatatgccac 27181 aatttacagc gccataggtg catgctgcca agatccccgc ttccccgcta tgcgcagaga 27241 agagcttaat tctgttgtct tcgaagtgag tattctaagc ccattgacgc tactagacga 27301 cgaccctagg aaataccttg agttggtgca ggtcggccgc catggccttg tagtgaagag 27361 ggggccttac tctggcttac ttctgccaca agtggcagtc gaagagtgct ggtctacaga 27421 agagttccta atacatacgt gtgtgaaggc gtggcttccg ggcgattgtt ggctagatcg 27481 taggacaaaa ctctacatat acgaggcaca gatattccgg gagagagaac ccaacgagga 27541 ggtataccaa agagatctat taggcgagct agccaagtgc cgaaaatagc tatacgtagt 27601 caaggaattc actcaaaaag cgtatcgtga ggtagtcaag atactgcgat cctaccgcca 27661 caagcttttt gccacctctc cttattacat atacatactc accaccgcgc tctgcctgaa 27721 gaagatctac atccagcttt tcgtacatat cgacgtccat cctctctcct atttccttat 27781 ctccaagctt aacgtactta aaccctagta agtctctcag ctcttctagc gaggagggta 27841 tgtaccccac cctcccataa ggcgggataa ccttatccaa cctctctttc aactcgacta 27901 cttgcctaat aatttcttgc tctcctggcg tgtacctagt ccctagctcc ggaggagggg 27961 gaggagtcct cctcgcaatg aagaatatga ttaccccaag cacgactaga gccaatacaa 28021 gagctataac ctcagggact tggaggtaca tatctactag aaacctatca atatttaata 28081 actacaatga tctttccgcc tgggcatttc ctcacatatc agaagaccct tagctcttca 28141 ctccgtgcct agatataatc cgatatttat ttcttctcat aacaatcttc ccaagcctat 28201 ggagattccc caagaacatc atagcgagac ctagcaccac cagctcgtac tcgttgccca 28261 ttacccccat cactaacagg aagcctccgt acacagttgc catgtgtata aacataacaa 28321 gattctcaac cgcttttaaa agagccacaa ataactaaca ctgaaccggc tctattttca 28381 agatctcccc agcaatctcc accacacgta ttctgcaacc cttctttacc ggtgtatcag 28441 aaacagccct ccagtattct ccgaagacta tcacaaagcc gggagatcca ggccctatat 28501 cgtccactgc caccccctct gcccccttga gagttgtcaa aatttcagag ggcggcctct 28561 gtttatggat aataactgcc ttgtacacga caaagacgag aaatcctaga agtattgcta 28621 tgtttacata taggccaagc tggatgagcc accaatccct gatgtggata agctctccac 28681 tgaaaacgtt agcaggatag gcggataaga atcccactac tagcaggacg gcgcctacgc 28741 cggccacggc gccgtgtgcc gccatgccca ttaatatctc tgccagtatc aacacggcgc 28801 ccataattat aagcgcgagg cccaaccacg ccgttggcaa aatcgagaac atagatataa 28861 ccagcaatac tatggccgcc accgcggcgg cggggtggcc tgtgataaac gccgcaagca 28921 gtaacaaaaa cgccaagaga gacaagacgc tggacatcac tgggtcgctt agccacatct 28981 gtaaagtttc agtaagtgaa ggttcgacac gccttatcac cgggctctct accactagct 29041 ctgtttgctg gtttcgcaac aacaccgtca tgccgtttat cttcttcaaa aggtcatcta 29101 caccggtggc caccacgtct attaccctat atttcaacgc cgtctcggcg tctaggttaa 29161 tattctgggt aatacagaga cgggcaaaag taccgttcct gccatacgac ttagacacag 29221 tttcgagata tcctatcaat gcgtttagaa tcttagactc atttaccggg gttccaccag 29281 atatcggctg acaagagcct attacagtat gcggcgccat ggcggcgatg tgggtcgata 29341 gcagtatata agtccccgca gaccaggcat agctgtagtc cgggtagaca tatcccacaa 29401 caggcacggg ggagttgcca atctccctta ttatctggag agtggggtct gccaagcctc 29461 caggagttga taacaatatg agcacaagcc cgttgttctg ctcagcgagg gatatagctc 29521 gctgtatctg cgagtaggta taggggccta caaccccgtt aatttcaact acataaactg 29581 acgtagccac ataggcatag gaaaaggcta ctaacaacag tagaatcgct attctcatta 29641 cttctgttgc tctcttttag atatcgctaa ggggagggcg acgtactcca gggtgggcgg 29701 agtcacaatt atcaggttgt gctcccgagc tatttcaatc aacgcgtcta tcatcctgag 29761 ctgaacagcc gtcgggtttt gcgaataccg ctccgcagcc tctaggtata tcttgctagc 29821 ctcgtactca gcagaggcca aagttatctt cgcccgcctc accctctcgg cctctgcttg 29881 actcgccatg gcacggagca acacgtcggg tagtttgata tcctttatag ccaccgcgct 29941 taccttcact ccccacggcg tgacatgctc atcgactatt gaggcaattc tcttagcaat 30001 ctcgtcccta tgcgtaagga gtgtgtctag atctaccata cctaccacat cgcgtagagt 30061 cgacgcagca tatatagcca cagccgggac gtgattgcgc acagttaagg ctgtttttag 30121 ggggtctatc acacggagat atatagccgc gtctatggtc acctccacgt tgtccttagt 30181 taatgcgcgc tgcgcaggta cgtcgacgac ctcaactcta aggtcatacc tcattattgt 30241 ctcaattatt gggatgatga agaccaagcc agggcctacg actcctacaa cacggcccaa 30301 cctgaactta acagctctct gatactccgg gatgatacga atagcagaag aaagtatggc 30361 tacaagaatt atcaacgcaa agaaaaccaa agcggcaaag actatctgtt ctatttggag 30421 tagcatatga caatatgtaa ctgagtataa aagcttaagt ctacagaaat ttttaatcta 30481 gacaaataac tggctaacta gatgaggtaa acacggggac gggctgaaaa tgatgtaaat 30541 tccgcgctcc cgataatact cagccgcgag aagtctcttc acagttctgt cagtcctgga 30601 gtcatcaact tttatattgt gaacatgtac agaccttcac atgttgaaat tcgaccaaat 30661 tttaaaagag ctagaggagg tggataggct agtaaagagc gtagaggatg taaaaaggca 30721 agttgcaatc agcgcagaga gcattgccaa aaaacattca gaagaggtag ttaaaaggat 30781 tgaagaaatc gtaaaaaacg ccattaacga atataaaata aaaactatag aagagacgaa 30841 aaaagaggcc gaaaaaatcg ctactgacgc tgaggaaaga gccaaaaata ttgtttccaa 30901 ataccaacaa agaaaagagg ctattttgaa aagagttctt gagatactca acttatgagc 30961 tcgatactcc ggagaccgta tctagggcct agagtaagag gactacgcat taaagaactc 31021 ccccgagata agctcatatc tctagcatat gctaatactc ttgacgaatt tttaaacata 31081 ctaaaaacta cccactacag tatcacgctt gacagattaa cacgtgaaaa tatttcagaa 31141 ctacgtagaa accttgtaaa aaactaccta gatactgtca gatctatatt tttaagttct 31201 ggaagagatg taaaaaacgc catactcctt tctcttaaat acttcgagta tgagaacatc 31261 agaaacctag ccattgcaat aaaggctggg aaaaacccag aagattacat cctatgggag 31321 cccttggaat tcacgcgtag gcgtcacata atcgcaggtc tactaggcgt aaaaaacatc 31381 gaggaaattg aagaaaggct tagaaatcta aaacacccag catacaaggc gtttcagctg 31441 tctagcaaat atggcgagga aaaa //