LOCUS NC_009332:5 24690 bp DNA linear BCT 07-SEP-2013 DEFINITION Streptococcus pyogenes str. Manfredo chromosome, complete genome. ACCESSION NC_009332 SOURCE Streptococcus pyogenes str. Manfredo chromosome, complete genome. COMMENT locus start: 1638763; locus end: 1663452 COMMENT n1_4mer:GRV/n1_4mer:RV = 2.011705; n0_4mer:D = 24.063716; n0_4mer:PS = 36.624437 FEATURES Location/Qualifiers source 1..24690 /organism="Streptococcus pyogenes str. Manfredo chromosome, complete genome." gene 1..1322 /gene="ska" /locus_tag="ska" /db_xref="1638763..1640084" gene complement(1420..1863) /gene="" /locus_tag="" /db_xref="1640182..1640625" CDS complement(1420..1863) /gene="" /product="D-tyrosyl-tRNA(Tyr) deacylase" /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA SQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH" gene complement(1878..4109) /gene="relA" /locus_tag="relA" /db_xref="1640640..1642871" CDS complement(1878..4109) /gene="relA" /product="GTP pyrophosphokinase" /translation="MRNEMAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHF YQVRKSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDA RDIVDGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLR KDKQERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRRER EALVEAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVM ETQSDVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKD MHQVAEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKE DIFSERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKT GDVVEIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQE QGYVANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERA KAKAEAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGY ITKGRGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLND VLQILSNSTKSISTVNAQPTKDMKLANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKR TNG" gene complement(4349..5047) /gene="scl" /locus_tag="scl" /db_xref="1643111..1643809" CDS complement(4349..5047) /gene="scl" /product="collagen-like surface protein" /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEAPAAPL TSEQRQKEIDKIKQEIQTKYPKASEEKFWESSFWGRKYFNEQEYLKSLQTFTEQRLQD IVNLIEKGATKGDKGDAGPKGERGPAGQPGEKAPEKSPEVTPTPETPEQPGEKAPEKS KEVTPAPEKPADKEANQTPERRNGNMAKTPVTNNHRRLPATGEQANPFFTAAAVAVMT TAGVLAVTKRKENN" gene 5421..5903 /gene="" /locus_tag="" /db_xref="1644183..1644665" CDS 5421..5903 /gene="" /product="flavoprotein NrdI" /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH ETFPIKEEFVAILPTYLEGGNGVDSGEVESLTTPLGEFIAAHGNAQRCLGIIGSGNKN FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQLIMEASSRHSSNDTQTLPNS" gene complement(6296..7114) /gene="" /locus_tag="" /db_xref="1645058..1645876" CDS complement(6296..7114) /gene="" /product="endonuclease/exonuclease/phosphatase family protein" /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYHEG VAILSKQPIHVSDILVSAMADETNYHTRRSLIAKTRLDGKEVAVVNVHLSWFDKGFLG EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV ADIDGWQGNKEALKVDHVFTSKDFIIRSSKTTFEGGDAPVVSDHYGLEVTLDWR" gene complement(7197..9383) /gene="" /locus_tag="" /db_xref="1645959..1648145" CDS complement(7197..9383) /gene="" /product="PTS system, glucose-specific IIABC component" /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI NHDSAFLASLGNIIAQIGWVVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI TGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPKVNMSQLT SKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVA GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA DLAAIQSAERETTIVVAFTNTTEIQDVTLTSLGNQPAKTKVATVEL" gene complement(9738..10487) /gene="" /locus_tag="" /db_xref="1648500..1649249" CDS complement(9738..10487) /gene="" /product="16S ribosomal RNA methyltransferase RsmE" /translation="MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLADEAEVVLVFDDG VKYLAKVTNSMAQELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNVVPEVHLFEQKTEFLKSLSS FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPAEITQFEAAGAIK VGLGPRIMRAETAPLYALSALSYALELQASK" gene complement(10487..11440) /gene="prmA" /locus_tag="prmA" /db_xref="1649249..1650202" CDS complement(10487..11440) /gene="prmA" /product="50S ribosomal protein L11 methyltransferase" /translation="METWQEVTVHVHRDAQEAVSYVLIETGSQGVAIADSADYIGQKD RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKDQGYLILSGIISEK LDMVLEAAFSAGFFLETHMIQGEWNALVFKKTDDISGVIGG" gene complement(11511..11981) /gene="" /locus_tag="" /db_xref="1650273..1650743" CDS complement(11511..11981) /gene="" /product="hypothetical protein" /translation="MAKYGFLSVIEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF AQFLNDVAIEGHSDLMDFLADDSKVDFGLEWNAQAFEEGQQGLEEGESYPYPRY" gene 12154..14127 /gene="" /locus_tag="" /db_xref="1650916..1652889" CDS 12154..14127 /gene="" /product="surface-anchored amidase" /translation="MKYSRRYPSQTRQMLLALLLMTASLQAGAMTTYADEVNTNHQPP TAQVEASKPTAMESVTSPADQTHPISTQEASSPLHPLTTEATPAAQESPITLEDYKAA SASQLAEWARQQRLTGQQLLDFALETIKETNPELNNVISLREPLARQESEQMTDEGQP FYKVPILVKGLGHTVAGSSNTNGLAFLKDKTSSSTSAFVKQLQKAGFIVVGQSSFPEM GWINVTNSNLYGNTHNPWQLDQNPGGSSGGSAAAVASGQVSLASASDGGGSTRIPASW SGLIGLHPTRGILEGNPTSERSNVSHFALTKSMEDTEKLFQFLLKDKAKAQQNPQRLD TSIPIAYSTQTPAGTPISEEAIAAIKEAVAFLQEQGYQTVEVPYPVDGKLMMQYYYTI AASAAPSINFMAQQTLKRPLQKEDVELLSWALYQTGKDLTKEDVNKAWEGIAAMTEQL NQFYQKYPIFLTPTTAYPAPAADYHHIPKDLVAQLSDMSGLSKEEKLGLIYRQWLPAW TLTPFTQLANLTGTPSLSLPTHVTKSGLPLGILVNSGAHNDSLLLQLGQLFEKANRFH ILTAGKKGLLETPTHEHNLSTQSENKQDVAIPVTYQTKGFTTVPTKGQNGLVTLPQTG DGQSKGVLLTSYISLFLGTLFLAGSFWSNKVKD" gene 14312..16069 /gene="" /locus_tag="" /db_xref="1653074..1654831" CDS 14312..16069 /gene="" /product="chorismate binding enzyme" /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKTLDQVDPVIQQVQHYQ ELGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP NQWVSATQKKAYQKTIETIHREMRQGNTYQVNYTIQLTQELNAADSLAIYNKLVVEQA AGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNTWLDQQEHDWLQAD GKNRSENMMIVDLLRNDMGKICQIGSVCVDRLCEVERYSTVWQMTSTIVGDLKADCDL IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFL EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL EPLSAEFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN LFIQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL YPLNLELTHLDALLAKSQA" gene 16102..16668 /gene="trpG" /locus_tag="trpG" /db_xref="1654864..1655430" CDS 16102..16668 /gene="trpG" /product="anthranilate synthase component II" /translation="MILLIDNYDSFTYNLAQYLSKFDETIVLYNQDPNLYDMAKKANA LVLSPGPGRPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL FGLQFHPESIGTPDGMTMIANFIAAIPR" gene 16701..17969 /gene="" /locus_tag="" /db_xref="1655463..1656731" CDS 16701..17969 /gene="" /product="recombination factor protein RarA" /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL VGHHYFEANETGKYERALGSNKERIDKLSD" gene 18255..18327 /gene="" /locus_tag="" /db_xref="1657017..1657089" gene 18468..18908 /gene="" /locus_tag="" /db_xref="1657230..1657670" CDS 18468..18908 /gene="" /product="acetyltransferase (GNAT) family protein" /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLAFAEDYL RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI" gene 18963..19469 /gene="" /locus_tag="" /db_xref="1657725..1658231" CDS 18963..19469 /gene="" /product="topology modulation protein" /translation="LKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERS DHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLN YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHKTIVLTNQKQL SHYMNTIN" gene 19718..20419 /gene="smeZ" /locus_tag="smeZ" /db_xref="1658480..1659181" CDS 19718..20419 /gene="smeZ" /product="mitogenic exotoxin Z precursor" /translation="MKKTKLIFSLTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY SDIVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKTGDKIAVFSVPFDWNYL SKGKVTAYTYGGITPYQKTSIPKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLK VRKFLIAQHQLYSSGSSYKSGRLVFHTNDNSDKYSFDLFYVGYRDKESIFKVYKDNKS FNIDKIGHLDIEIDS" gene 21148..22782 /gene="dppA" /locus_tag="dppA" /db_xref="1659910..1661544" CDS 21148..22782 /gene="dppA" /product="dipeptide-binding extracellular protein" /translation="LIVSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDE LVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTW SFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEA HSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPY FKKWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYV KKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPF WNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVE VAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTN ITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTY IGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK" gene 22895..23872 /gene="dppB" /locus_tag="dppB" /db_xref="1661657..1662634" CDS 22895..23872 /gene="dppB" /product="dipeptide transport system permease protein DppB" /translation="VKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNY DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL SSEYVLFARARGETQWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV" gene 23869..24690 /gene="dppC" /locus_tag="dppC" /db_xref="1662631..1663452" CDS 23869..24690 /gene="dppC" /product="dipeptide transport system permease protein DppC" /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE QPSVGIILSEAAKHISLGNWWLVVFPGLYLILVVNAFDTIGESLKKLFYPQTDHF" ORIGIN 1 atgaaaaatt acttatcttt tgggatgttt gcactgctgt ttgcattaac atttggaaca 61 gtcaagcctg tccaagctat tgctgggtat gaatggctgc tagaccgtcc atctgtcaac 121 aacagccaat tagttgttag cgttgctggt actgttgagg ggacgaatca agaaattagc 181 cttaaatttt ttgaaattga cctaacatca cgacctgctc agggaggaaa gacagagcaa 241 ggcttaaatc caaaatcaaa accatttgct acagataaag gcgcaatgtc acataaactt 301 gaaaaagctg acttattaaa ggctattcaa gaacaattgg tcgctaacgt tcacagtaac 361 gacggctact ttgaggttat tgattttgca agcgatgcaa ccattactga tcgaaacggc 421 aaggtctact ttgctgacaa agatgattcg gtaaccttgc cgacccaacc tgtccaagaa 481 tttttgctaa gcgggcatgt gcgcgttaga ccgtatcaac ctaaagccgt tcacaactca 541 gctgaacgcg ttaacgtcaa ctatgaagtg agctttgtct ccgaaacagg aaatttagac 601 tttacgccat cgttaagaga tcgataccat ttgaccacac tggcagttgg tgactctctt 661 tcatcacaag agttagcagc aattgcccaa tttatcctat caaaagagca tccagattat 721 atcattacaa aacgtgactc ctcaatcgtc actcatgaca atgacatttt ccgtacgatt 781 ttaccaatgg atcaagagtt tacttaccat gtcaaaaatc gggaacaagc ttatgggatc 841 aataaaaatc tggtcaggaa gaaaaaatga acaacactga cctgatctct gagaaatatt 901 acatccttaa aaaaggggaa aagccgtatg atccctttga tcgcagtcac ttgaaactgt 961 tcaccatcaa atacgttgat gtcgatacca aggacttgct aaaaagcgag cagctcttaa 1021 cagctagcga acgtaactta gacttcagag atttatacga tcctcgtgat aaggctaaac 1081 tactctacaa caatctcgat gcttttggta ttatggacta taccttaact ggaaacgtag 1141 aggataatca cgatgacacc aaccgtatca taaccgttta tatgggcaag cgacccgaag 1201 gagagaatgc tagctatcat ttagcctatg ataaagatcg ttataccgaa gaagaacgag 1261 aagtttacag ctacctgcgt tatacaggaa cacctatacc tgataaccct aaggacaaat 1321 aacctcgatc ttctaaaacg atgagattaa ctgacaaaaa aagcaagcaa cacgctatca 1381 acagttgctt gcttttttct aacctcttag ttgtagagac tagtgacatt tcgtgtctaa 1441 aataatcgta actggtccat cattgatgag actaacctgc atatctgccc caaaaacgcc 1501 acgctcaact ggcacaaact ctgccaattg ttcattaaag ctatcataca actgactagc 1561 caaatctggc ttagcagcac cagtaaaggc aggacggttt ccctttttgg tgtcagcata 1621 aagggtaaat tgcgacacag ataagatact gcccttgatg tcttggatag actggttcat 1681 cttgccatca gcatctgaaa aaatgcgcat gttgactatt tttcgcacag cgtaagccaa 1741 atcttctgca ttatcatctg gtcccacacc tactaacaac aacaatcctt gattaatagc 1801 gccagcaatt ttcccatcaa tagaaacaga ggcctctttg acccgttgca agacaagttt 1861 catggtttta tcctttctta gccattggtc cgcttcacgc tataaacatc tggaactgcc 1921 ttgatttttt cgacaacagt ggtcagatgc gtcagatttg gaatgccaaa gctcacgtga 1981 atattagcta acttcatgtc tttggtcggc tgagcattga ctgtcgatat gctcttggtt 2041 gagtttgata aaatttggag cacatcatta agcagaccac tacgattgag cccatagata 2101 tcaatttcag cctgataatc tttactcgaa ttgtccaaat cccactcgac ctcaatcaag 2161 cgttcttggt agccatcttg actcttaatg ttatgacagt ccgatctgtg aatcgcaatg 2221 ccacgccctt tggtaatgta gccgtcaata ggatcaccag gtacaggatt acaacacttg 2281 gcaatccgca tcaagaggcc tgatgctcct tggataatga ctccattttc actgcgaacc 2341 ttgagcacat ctttgttttc gtgtttgacc tcaccgccct taaccaattc ttctgcttct 2401 gctttagcct tggccctttc ttcttcacgg cgctcttttt cggttaactt gttaaagaca 2461 ctgataggac taatgtcacc aaacccaacg gctgcataga gtgattcttc actcttcaca 2521 ctgacttttg gaaggattgc ttcaatgcgt tttttgtcaa ggtatttatt ggcaacgtag 2581 ccctgctctt gaaaataaga caccaacaaa tcacggcctt tattcactga caattccttg 2641 tcttgatttt taaagaactg acgaattttg ttgcgagcct tattggtttt gaccagtttt 2701 acccagtctc gactagggcc aaaggaattg gcattggtga tgatttcaac cacatctcct 2761 gtttttaact tggcagtgag aggaaccata cgtccattaa ccttggcacc tgttgctttt 2821 tcaccgattt gcgtatggat cgcataagca aaatcaatag gacctgattc ttttggcaac 2881 tcctgaacgg cccctgtcgg tgtaaagaca taaatccgtt cagaaaaaat gtcttctttg 2941 accgaatcca caaagtccac tgcatcgcca tttgaggcat cttgcaattc taccagctct 3001 ttgatccagt tcatgccaac ggcttgctca gcctgattga ccttaccacg cacgcctttt 3061 ttataagccc agtgagcagc aaccccgtac tcagccactt gatgcatgtc cttagttctg 3121 atttgaatct caataggtcc ttttggccca tacacagtgg tatgaatcga ctggtagcca 3181 ttagctttag gagctgcaat ataatccttg aagcggcctg gcatgggacg ccaaagctcg 3241 tgaatatagc caaccatagc atagacatcg ctttgcgttt ccatgacaca acgaatggca 3301 atcagatcaa aaatctgatc gaaacgtttc tttttgtccc gcattttccg ataaatcgaa 3361 taaatgtgtt ttggtcggcc atacacatct ccaaacaagc cttgttgtgt cgtataggtt 3421 ttgaccttac tgacaatagc ctctaccaaa gcttcacgct cgcgacgttt ttctttcatc 3481 atatgggaaa ttttgtaaaa ttcggtttca ttgaggtaac gaaaagccaa atcttctagt 3541 tcccatttga tgcgactaat ccccaaacga tgcgccaagg gggcatagat ttccatggtt 3601 tcgcgcgaaa tgcgctcttg tttgtccttg cgcaaatgtt tgagggtgcg catattatgc 3661 aggcggtcag ccaatttcac caaaatcacg cgaatatctt tggacatagc catcagcatt 3721 ttgcgatggt tttcggcgag ttgctcctca tgagatttgt actcaacttt acctaacttg 3781 gtgacaccat caacgatatc acgagcatct tggccaaagt ctgcttcgat ctcatctaag 3841 gtaatgtccg tatcttctac gacatcatgt aaaaagccac aggcaactgt cacagcatcc 3901 agatgcaaat cagccagaat ccccgccacc tgaatcggat ggacgatata gggttcgcct 3961 gactttctca cttggtagaa atgggccgct gttgcatatg ctaaagcctt tgccacaaaa 4021 gccacatcag tcttggtcat ataggtggcc gctaaggcaa tgacttcttc tcctgttacg 4081 ttcattattt ttgccatttc gttcctcatc tagcatttct tttccctatt ttaacacttt 4141 acacacaaaa gcaaaaggca gaatctgcta agaaagcgct tagtgtgacc ttttcttaga 4201 aaacggttag tgagctgctt ttgatatctt ttgggatctc tcaggcgtga gcatgatacc 4261 aaaggcctgc tcccgaccaa aaatagagag aaccaagggg ctctctctat tatgtttgct 4321 tatcagtaag gcctctcaat ttagaggatt agttgttttc tttgcgtttt gtaacggcta 4381 ggacaccagc tgttgtcatc actgctactg ctgctgctgt aaagaatggg ttggcttgct 4441 caccagttgc tggtagacgt ctgtggttgt tggttacagg tgtcttagcc atattgccat 4501 tgcggcgttc tggcgtttgg ttagcttctt tgtcagcagg tttttctgga gctggagtta 4561 cctctttgct cttttctgga gctttttcac ctggttgctc tggcgtttct ggcgttggtg 4621 tcacttctgg gctcttttct ggagcttttt cgcctggttg gcctgctggg ccgcgctcgc 4681 ctttaggacc agcatcacct ttatcacctt ttgttgcacc tttttcaatc agatttacaa 4741 tatcttggag tctttgctca gtaaaagttt gtaaagattt tagatactct tgttcattaa 4801 agtactttct tccccaaaag ctactctccc aaaatttttc ctcagacgct tttggatatt 4861 tagtctgaat ttcctgttta atcttgtcaa tttctttttg tctctgctcc gatgtcagag 4921 gagcagctgg agcctcagcc ttaacgctgc ttgccccgcc tccaaaggct agaaggacgg 4981 cagcagctga ggttagtccg tagcgccaga ccagtttgtt gagattatgg tgctttgatg 5041 tcaacatatg ttgttctctc tttctctatt agatggtgtg ttttagataa aaataacatg 5101 gtagctagac ctgattatct ataatagagt gtgaaaacaa ttgtaaagtt ctcttttgtt 5161 gttcatcttt tagattttga ctgatcgctc ttttgtggag atcagagggc cactttggca 5221 cttgcctgcc tcgtttttaa gtcgagggca agcgcatcct ttctttaaga aggtcactct 5281 tttttgaaat gttgcttttt ttgactgcct gtaccttctt gtctggttgg ataccgctag 5341 gtttcttctt tacttgtttg ttggtcttga ttgtggtaag cttatgaaga aaccttgtag 5401 gataaaaaaa ggagacactt atgcctcaga ttacccttgt ttttattagc ctcagtggca 5461 acacccttag ctttgtcaag cggctatccc tttatctagc agacaattac gattaccatg 5521 tcaaacagat taacattaaa gatttgaagc acgagacttt tcccatcaag gaagagtttg 5581 tggcgattct acccacttat ctagaaggcg gaaatggcgt tgactctggt gaggtggaga 5641 gcctcaccac tcctttggga gagtttattg ctgcccatgg caacgcccag cgttgtcttg 5701 ggattattgg ctcaggcaac aaaaacttta accatcagta ttgcctgaca gccaaacagt 5761 atgccaaacg ctttggcttt ccactgctag gtgattttga gctgcgaggg actcctgatg 5821 acatttcgcg gttagcccag ctcatcatgg aggccagctc cagacactcg tctaacgaca 5881 cacagacatt gcctaacagc tagacagtct atagatgatc atagctgttt taaaaaagag 5941 cgcttttagg acaataacta cagagggccc taccctacgc cttgtgattt ctcagccttt 6001 gaaaagagcg atcacagtgc ttcttggggc ttgggatcac accaagcact cctagaaata 6061 cccccatgca gactttagca aggcaactaa acgcttggtg gtactttctg tgaagctcag 6121 atggttggtg acaaaaaagc cctggttttc tagggttact gacatgacta aagaggtcta 6181 accagctcta ccttgagctc gttagacctc tttgtgttct cctaatccct ctagacgatc 6241 gcagtttctt atgtgtcttg gcttctctta tgtggtgtgc ctgttagcac atgctctaac 6301 gccagtctaa tgtcacttct agaccatagt ggtcactgac gactggcgca tctccgcctt 6361 caaaggtagt cttagaagat cggatgatga agtccttgct ggtaaagaca tgatctacct 6421 tgagggcttc tttgttacct tgccagccat caatatcagc cacgatgcta tgatcaccaa 6481 acacatggtc agcaacctta tggctatctt gtaggtctag ggggctaccc atcatcactt 6541 gataaccgtc ttgatccgtt ggattgttaa aatctcccat aagtagcaag ggacagttta 6601 gtgtgagcag ttctttttct aatttctccc actcccctaa aaaccccttg tcaaaccaag 6661 ataggtgcac attgacaaca gcgacttctt tgccatctaa cctggttttg gctatgagtg 6721 agcgtctggt gtggtagttt gtttcatcag ccatcgctga caccagaata tctgaaacat 6781 gaataggttg ttttgataag attgccacgc cttcatggta aatgtcatag ccaatatgat 6841 tataagccca agaccaataa tagtgctgcc ctcgtttttg taaataatgg atcaagagca 6901 gggcaaaatg gtctttatga atgcttggtg tccctgaaag agcttgatat cttggtaaat 6961 ctgtggccag ctcgctctcg attaactgat tgatttcttg caagcaaatg atatcgtatt 7021 tttcagctaa aatatgctca gccaaagcaa ctaatttttt aagagtgttg gcttgcatcc 7081 acgaatgggt attcagtgtt aataccttgg tcattaatcc tcctttataa gacaagaaga 7141 gccatagggc ctaaaccagc tatggctatt acctatcact atctcgtgat gttttgttaa 7201 agttctacgg tggctacttt agtcttagca ggttgattgc ctaaagatgt caaggtcaca 7261 tcttggatct ctgttgtatt ggtaaaggct accacgatag tggtctcacg ctctgctgat 7321 tggatggcag caagatctgc tacgactaat aggtcacctg catgaacccg ttgcccttct 7381 gagactttga ctgaaaaagg cacaccattt aaggcgacgg tatcaagtcc cacgtgcacc 7441 agcacttcaa gaccattatc tgtcagtaaa ccaaaggcat gcttggtcgg aaagacactg 7501 gtcacaaggc cagctacggg tgcatagata ttaccatttg ttggttcaac cgcaaaccca 7561 tctcccatca tcttagcagc aaacacctgg tctttcacac ctgtgattgg gagaaccatc 7621 ccgtctgcca ctgatagcac atcttctgtc acgtgtttaa aatcttttgc gggagtcggt 7681 ttgctagtga gctgtgacat attgactttt ggaataacag cccctgagtc cagcaaatct 7741 tgaatatctg atttcaaaat atctgcttta gggccataga ccgcttgaac gccgttgcct 7801 ttttggatca agcccatagc gccagctttt ttccaatcgt cctcagcgcc aatcttagcg 7861 gggtctttga ccgtcactcg taagcgcgtc atacaagcat caacatcatc aatattgcct 7921 gccccaccaa ggagattaat gatttgtacg acttgagagt tgctatctgc tacttgggtc 7981 ggtgttgctt gagtgttatg gtcacccagt atatcggcat cgtagttgcc taaacggcca 8041 gctgttgcga gatgcatttt cttgatcatc atatccgcaa taaagtacat gataactgca 8101 aagaggatag aaacccaaac aaagttaatc acatccatgc ctaggcctgc tttaagggcc 8161 ataggggtac gggttagtag ctcaatgttc ccaaatgagt gaacacggag attcacaagg 8221 tcagccatgg caaatgaagc tccttgaaca agggcataga cgatgtaaag tggcattgct 8281 gcaaacataa ataggtactc aagtggctca gttacccctg tcaaaaaaac cgctgccgct 8341 gctgagatga acatcatttt gtatgtgtgt tttttatcgg catccacatt acggtacatg 8401 gctaaggcaa cccccatcaa tgttccggta gctccaatca tttgtcctac cttaaagcga 8461 gctggagtca cactatccat taagtgacta taggctgaag cgtctgatcc tttaaggtga 8521 acaaggtcag ttacccaagc aagccacaaa gggtcttgac caaatacttt tgtccccgct 8581 gctgcacctg tcatgacctc ataggttcca ccaagagctg tatagttcat tgggatcgtc 8641 aacatgtggt gaagaccaaa tggcaacaag agacgttcca aggtaccata taggaatggg 8701 gctaggattg gagctgaatc ttgtgaggag gcaatccaca tcccaaaact gttaatccca 8761 gactggatca ccggccaaac aacaaccaaa ataagggcta caaaaataga acgtaaaata 8821 acgacaaatg gtacaaaacg cttcccatta aagaaggtca aaacttcagg aagtttacgg 8881 taattatagt atttgttata ggccgttgct cctacgaacc ctgcaataat cccaacaaaa 8941 acccctgtgt ttaaagctgg agattccaag acactggtga aataatcttt aacgatcatt 9001 tgagtgccaa ggaggcttgt gatttttgct tctggatcag ctagcatagt actagacacg 9061 ccataaaaag cgcctgttat ccgattgatc aaaacaaaag caagacctga ggcaaaggcc 9121 cctccagctc tttctttagc ccaactacca ccaatggcca aggcaaatag caaatgaagg 9181 tttacaataa caacccaacc aatttgagcg ataatgttgc ctagagatgc caaaaatgct 9241 gaatcatggt taatcattgg aatagagttt ccgatactga tcattaaacc agccgctggc 9301 atgacagcaa taacgaccat aagacatttc ccaaattttt gccaaaattc gaaacgaaac 9361 agttgcttga atgatgtttt cattctatct ctcctttatt atcccctttt agccatagct 9421 gcccttaagg cgcttttgtg acacaatgat atagactaca actcagtgat gcaatcgttt 9481 gcattgatct gataccttta ttatactagc ctcgcaacaa tttgtaaagc gttttcttag 9541 acagatgtta gtcgtttttc ttcattaaat agtagtgtag ctcaccaaaa agatgacaag 9601 agcccatttc cttttttggt gatgagccca tcaacgctct tcaaaaaaca agaagcaata 9661 aaaaaaggcc gttgacacaa tcgtgaactg cctgttcgtt tctttagcct cttctttcta 9721 aagtaagcac agcttactta ttttgatgcc tgcaattcca aagcataact aagagcactt 9781 aaggcatata gcggcgctgt ctctgctcgc ataatgcgag ggcctaagcc caccttgatg 9841 gcacctgctg cctcaaactg agtgatttca gctggggaaa ttcccccttc tggtccaaag 9901 ataaagagga tttttgcccc tggcttaact tcttttactt cacgcgccaa ggtcgctagc 9961 tgacctgcct tagctgtttc ctcataagca atgaagatat gatcaaagct agaaaggctt 10021 tttagaaact ctgttttctg ttcaaaaagg tgaacttcag gcaccacatt tcgtttgctc 10081 tgctcagcag ctcctaaaac gattttagcc aatttgtctt cttttttagc taattttttg 10141 ccatcccatt tgaccactga ccagtctgct gggtagcccc acagcgcact tgctcccaat 10201 tcagtcactt tctgggcaat cgtatctaac ttatctcctt taggaaatcc agaagcaata 10261 gtcactttaa caggcaattc cacctgatct ggcaaagcct ctataatctc taactcctga 10321 gccatactat tggtcacctt ggctaaatac ttcaccccat catcaaagac caagacaact 10381 tctgcctcgt cagccaagcg catcacttga aacatgtgct tgatggtatc tttatcggta 10441 attgttacct ctttttctgc tttgccttta ataaaatact gttgcattag ccgccaatca 10501 ctcctgagat atcatctgtt tttttaaaga caagggcatt ccactcacct tgaatcatgt 10561 gtgtctcgag gaagaagcct gcgctaaagg cagcttccag aaccatatcc aatttctcag 10621 aaatgatacc agataaaatg agatagcctt ggtccttgac caaacggtaa gcatcatcag 10681 tcaataagac taagatatcc gccaagatat tggctacaat cacatccgct tcttggctaa 10741 ccccttttaa aaggtcgccg gcagccacat gaatgttgtc tgttccttgg tttaaatcaa 10801 tgttttcttg agccactcga acagccacat catctaaatc ataagcgtag atggttttag 10861 cacctagtaa ggaactggca atcgagagga cacctgatcc ggtccctaca tcgataactg 10921 tctcaccacc acgaaggatt tgttctagag caaaaaggct catcttagtt gtgggatgtg 10981 tccctgtccc aaatgccatt ccaggatcta atttaatcac tttttcccca gcagaagcgt 11041 cataatctgt ccaactaggg acaatggtta aatcatgcgt gatgcgagct ggttcatagt 11101 attttttcca attgtctgcc cagtcttcct cagctaattc ttgactgtcc acagtaacct 11161 gaccaacctg taacccaaaa ctagctaact ccgctaactg ttcattaatg gtcgcaataa 11221 catccgccaa attagtgcta cttgggtaat aggctgtgat agctatcatg tcagactgct 11281 ccacatctgg gtataactcc ccaaagcggt ccttttgccc aatatagtct gcgctatctg 11341 cgatagcaac cccttggctg cctgtctcaa tcaacacata tgaaacagcc tcttgcgcat 11401 cacgatgcac atgaaccgtc acttcttgcc acgtttccat aagtatgtcc tttctatttt 11461 gaccttttgg ttattgtcct aatagtgtta gcaccatctc gtgtgtcacc ttagtacctt 11521 ggataagggt aactttctcc ttcttctaat ccttgttgac cttcttcaaa agcttgcgca 11581 ttccattcca agccgaaatc aaccttgctg tcatctgcta agaaatccat caaatcgctg 11641 tgcccttcaa tagcaacatc gttgagaaat tgcgcaaagt aagctaagaa ttcacgagaa 11701 aagccctttt tagcgtcaaa aggaatagta accaaataat ctgctgcatc aaattgagac 11761 ttggcagggt tgtaaaagag cacatagtcc tcaaagacaa tatcatcttg ggtcacttcg 11821 ccactatcat caatggtttt tatggcctct ttattttgag cttctaaaac aaaagtcact 11881 tcaaccgcat gatttttctt gtcccaatcc atagcataat catattgaaa atgcttgtcc 11941 atttcttctt ctattactga taaaaagccg tattttgcca tctaattgtc ctttttccta 12001 acgattattt gcttccattg tagcataatt tgagctaact ttcactggca aatgctgact 12061 gatgggcctt ctgtatttta gtaagcgttt taccccttac tttcctccca ttatgttaaa 12121 ctaataagcg attatgatgt taggagaaaa agaatgaaat attctagacg ctacccttct 12181 cagacaagac agatgcttct tgccttgtta ttaatgactg ccagcctaca agctggagct 12241 atgactactt atgcggatga ggttaatacc aaccatcaac caccaacggc ccaagtggaa 12301 gctagtaagc cgacagccat ggaatctgtc acttcacctg cagaccagac ccatccaatc 12361 tcaacgcaag aggcttcgtc tcctttacac cctttaacaa cagaggccac tcctgccgcc 12421 caagaatctc cgattacctt agaagactat aaggcagcca gtgcgagcca attagctgag 12481 tgggctcgcc agcaacggct cacaggtcaa cagctgctag attttgcctt ggaaaccatc 12541 aaagaaacta accctgagct caataatgtc atttctctgc gtgaaccatt ggctcgacaa 12601 gagagcgagc aaatgacaga tgaagggcaa cccttttaca aggttcctat tctggttaaa 12661 gggttaggac acaccgttgc tggaagtagc aacaccaacg ggcttgcctt tttgaaagac 12721 aaaaccagct catctaccag cgcctttgtc aaacaactcc aaaaggctgg ttttatcgtg 12781 gtagggcagt cctctttccc tgaaatggga tggattaatg tgacgaattc caatctttac 12841 ggaaatacac ataacccatg gcagcttgac caaaatcctg gcgggtcctc tggtggctct 12901 gcagctgctg tggcttcagg acaagtcagt ctagccagtg cttctgatgg tgggggctca 12961 acccgcattc cagcttcttg gagtggcttg attggcctac acccaacacg tggcatttta 13021 gagggaaatc cgacttctga acgtagcaat gttagccatt ttgctctaac taagagcatg 13081 gaagacactg aaaagctctt ccaattcctc ttaaaagaca aggctaaagc gcaacaaaac 13141 ccacagcgtt tagacacaag tatccccatt gcttacagca cccagacacc agctggaaca 13201 ccaattagtg aggaagctat tgctgcgatc aaagaagctg tagccttttt acaggagcaa 13261 ggttatcaaa ccgtagaagt gccttacccc gttgatggta agctcatgat gcaatactat 13321 tacactattg ctgcttctgc agcgccatct atcaatttta tggcgcaaca aaccttgaaa 13381 cgcccccttc aaaaagagga tgtcgaactc ctatcatggg cgctctacca aactgggaaa 13441 gacttgacca aagaggatgt caacaaagcc tgggagggta tcgcagccat gaccgagcaa 13501 ttaaaccagt tctaccaaaa ataccccatc ttcttaacac cgacaacagc ctatcccgcc 13561 cctgctgctg attaccacca cattcctaaa gacctagtag cacagctcag tgacatgtca 13621 ggcttgagca aagaagaaaa attgggcctt atttaccggc aatggttacc tgcatggacg 13681 ctaacaccat ttacccagct tgctaacctg acgggaacac catccttgtc tttaccaacc 13741 cacgtgacga aaagcggtct acctcttggc attttggtga atagcggagc tcataacgac 13801 agtctcctgt tacaactggg acagctcttt gaaaaagcaa atcgtttcca tatcctgacg 13861 gctggcaaaa aaggattact agaaacacct acacatgagc ataacctctc aactcaatct 13921 gaaaacaagc aagacgttgc cattccagtg acttatcaaa ccaagggatt tactactgta 13981 ccaaccaagg gccagaacgg cttagtaacc ctccctcaaa ctggtgatgg tcagtcaaaa 14041 ggtgtattgt taactagcta catcagcctt ttccttggaa ccctcttctt agcaggaagc 14101 ttctggagca ataaggtaaa agactaggct attgtcgtcg gagatttaac ctacctaaac 14161 attcactgct gcttgcctta cgataagagt atattgtagt caatcaagac tgaactttct 14221 tagtaaacgt tccgtctttt cacgtggcca aaagacagtt gttgcctgtt ctcattaggc 14281 ctggcaaccg cttttatgat ataatttggg tatgcataga aaaacgatta ttgatttcaa 14341 agagctcggg caacgctatc tttttgatga gccattagta gaattggtag ccaaaacctt 14401 agatcaggtc gatccagtca ttcagcaagt tcagcactac caagaactag gctactacgt 14461 ggtgggttac ctcagttacg aagcagctgc tttttttgac aatgccttac aaacccataa 14521 tgacagacta ggcaacgagt accttgccta ttttacagtg cacaaaacct gtcaaaaaaa 14581 agacctacct cttgattatg acagtattac tatccctaac caatgggtca gcgccactca 14641 aaaaaaggcc tatcaaaaaa ccattgaaac cattcaccgt gagatgcgac agggcaatac 14701 ttatcaggtt aactatacca ttcaattaac tcaggaactc aatgcagctg acagcttagc 14761 catttacaat aaactcgtcg ttgaacaggc tgctggctac aatgcctata tcgcccatga 14821 tgactttgct gttatttcag ctagtcctga attgttcttt aaacaagaag gcaacaggtt 14881 aactactagg cctatgaaag gcaccaccaa acgaggggtt aatacctggc tggatcaaca 14941 agaacatgac tggctccaag ctgacgggaa aaatcgctct gaaaacatga tgattgtgga 15001 tttgctccgc aatgacatgg ggaaaatttg ccaaataggc agtgtttgtg ttgataggct 15061 ctgtgaggtc gagcgatact ctaccgtctg gcaaatgacc tcaactattg ttggtgacct 15121 caaagcggac tgtgacctga tagacattct cacagctctc tttccttgtg gctctatcac 15181 gggggcacca aaagtctcca ccatggcaat tatcacatct ctggagccaa aaccaagggg 15241 gatttattgt ggaagtattg gcatttgcct acctgacggt cgccgtttct tcaatgttcc 15301 cattagaacc atccagctca gtcataatca agcgacttat ggtgtcggag gcggcatcac 15361 ttggcaaagc aagtgggaag acgaatacga agaagtccat caaaaaacag cttttctcta 15421 tcggcacaaa caaatctttg acctcaaaac aaccgccaag gtggaacaca aaaaaatagc 15481 cttccttgag caacacctca atcgccttaa agaagcagcc acttattttg cttaccctta 15541 taatgaaaaa gctttgcaga aacaactgtc aacctatttg gaaaataaga ataatgctgc 15601 ctaccgcttg atgattcgtt tatccaaaga tggaaaaatt agcctctctg atcaaccctt 15661 ggaacctttg tcagccgagt ttctgacagc tcaactctct ttacagaaaa aggacgtgac 15721 agcttcgcct tttacctact ttaagaccag ctaccggcct catattgagc aaaaatctta 15781 tgaacagcta ttctataacc aagcggggca attattggaa acgtccattg gcaatctttt 15841 tatccagctg ggtcagaccc tctacacacc accagtggct gtggggattt taccaggact 15901 ttttcgccaa gagctgctag ctactggtca agctcaggaa aaagaggtga cactagctga 15961 tttaaaagag gctagcgcta tttttggagg aaatgctgtc cgtggcctct atcctctcaa 16021 ccttgagctt actcaccttg atgccctctt agctaagagt caagcctaaa ctgccactca 16081 tcttttgtta ttaaggaacc tatgatactc ttaattgata attacgattc atttacctac 16141 aacctcgccc aatatttaag taaatttgac gagacgattg tcttgtataa ccaagaccca 16201 aacttatatg acatggccaa aaaagctaac gctctagtcc tctcacctgg tcctggtcgg 16261 cccaaggaag ccaaccaaat gccaaaactc attcaagatt tttaccaaac aaaacctatc 16321 ttaggagtgt gtctgggaca ccaagcgatc gctgaaacat tagggggaac cttacgcttg 16381 gccaaacgcg tcatgcatgg gagacaaagc accattgaaa cgcaaggccc tgctagtctt 16441 tttcgctccc tgccacaaga gatcaccgtc atgcgctacc attccatcgt tgtggatcag 16501 ttaccaaaag gttttagcgt aactgctaga gactgtgacg atcaagaaat catggccttt 16561 gaacaccaca ccctgccact ttttgggcta caatttcacc cagaaagcat cggaactcct 16621 gatggcatga ccatgattgc caacttcatc gcagctattc cccgttaatc ccatccccca 16681 aaagaaagga ggacagttac atgcctgatc atttagcgct cagaatgcgc cccaaaacca 16741 tttcagaggt catcggacaa aaacaccttg ttggcgaagg caaaatcatc cgtcgcatgg 16801 tggaagcaaa tagactatcg tccatgatcc tctatggccc tccaggaatc ggtaaaactt 16861 ccattgcttc tgctattgct ggtactacta gatatgcctt tcggaccttt aatgccacca 16921 ttgacagcaa aaaacgtctc caagaaattg cggaagaagc taaattttct ggtggcttgg 16981 tattattact agacgagatt catcgccttg acaagacaaa acaagatttt cttttaccct 17041 tacttgagaa cggcaccatt atcatgattg gcgcaaccac tgagaatccc ttcttttcag 17101 tgacacccgc tatcagaagc agggtccaga tttttgaatt ggaaccactt tctaacgagg 17161 atattaaaac agccattcag ctagcaattt ccgacaaaga acggggattt ccttttttag 17221 tgacaattga tgatgaggcg ctagatttca ttgttaccgc cacaaatgga gacctacgat 17281 ctgcttataa ttccttggat ctagcagtca tgtctacttc tcctaatgaa gatagtagcc 17341 gtcatattag tctagagaca atggaaaata gtctgcagcg tagttatatt accatggata 17401 aaaacgggga cgggcattat gatgttttat ctgccttaca aaaatccatt agaggttctg 17461 atgtcaatgc cagcctgcac tacgccgctc gtttagtaga agctggagac ttgcctagtt 17521 tagcaagacg attgaccatt attgcttacg aagatattgg cttagccaac cctgacgccc 17581 aagttcatac cgtcaccgca ctagatgccg ctcaacgcat tggttttcca gaagctcgta 17641 ttcttatcgc taacgtggtc attgatttgg ctctatcacc taaatccaat tcagcttatt 17701 tagctatgga tgcagcttta gctgatttga gaacatcagg taacctcccc attccaaggc 17761 atcttagaga cgggcattac gctggcagca aggacctagg caatgccaaa gattacctct 17821 acccacacgc ctaccctgaa aaatgggtca aacaacaata cctaccagat aaattagtag 17881 gacatcatta ttttgaagcc aatgaaaccg gtaaatacga acgcgcactt ggttcaaata 17941 aagagcgtat tgataagctc tcagattgac tgctagtttt aaaaatcgca accgatttca 18001 aaaatcgata attttgcttg aaaaaatttt aaaaagtggt attataaaag tacagaaaca 18061 ttgctgtggc atacgaatcc acatctaagt gttgaccgac tatttctttg tattttcggg 18121 aaacaaagac tctttctagt ctgcaagccg tttcacgcgg acgcaacttc caagaaagag 18181 cgcgttaccc acctgcttat actgcgcggg ctcaatacaa aaacgtggat caccggtgcc 18241 aatacagcat tcttgcctcc ttagctcagt tggtagagca gtagactctt aatctatggg 18301 tcacaggttc gagccctgta gggggtatac aactatacat gaaaaaacct ttgtttaaag 18361 gctttttttg cttgtcagaa gaggatttgt tccatcattt atccccgcag taattttttt 18421 atggtatgat accaattaaa gcgcttaaga ttaaggtgga gactgttatg aaaataattg 18481 agtacaaagg aaattacaga gatgacctca tttttatggt cttggaagca aaaaatgcct 18541 taaggagaat tcccagcatt aacccggatc ttttgacaat tgaaacaagt tatttggaaa 18601 aaggggattg tttttggcta gcggtcaatg aagaaagtcg tgttattggc tcaatcgctt 18661 attcttctat tcccaaaaca aatgaggtct tcttgcaccg tctcttcatc aaaccaagct 18721 taaaacatca aggcattggc agtcaacttc tggcgtttgc agaagattat ctaaggaaaa 18781 tcggcaagag tcatgttcgt atccacttag gtcaacctaa agaacaatgg tttgagtctt 18841 atcggtttta tcctaaacat ggttatcaat tttatgatga cacgcatctc atcaagaaac 18901 taatctaaac acatttcata ccctttatag tcatttcata cgtcattttt aggaggtatc 18961 cattgaaaat tgccatcatt ggacatagtg gctctggaaa gtcaacctta gcacgatttt 19021 taggccaaca ttaccattgt gaggtattcc atttagacca actacacttc tcatcgaact 19081 ggcaagaacg gtcagatcat gacatgatag ctgatttatc aacatgcctg ctcaaacaag 19141 attggattat tgaggggaat tatgccaatt gtctctatga agagcgcatg agtgaagctg 19201 attacattat ctatgttaat ttcagtcggt ttcattgtgt ctatcgagca tttaagcgtt 19261 atttaaacta taggggaaaa acgcgtcctg atatggctga caactgtcag gaaaaatttg 19321 acgttgcgtt tgtgaaatgg attctactag atggacgttc aagaaaccag ttaaaaaaat 19381 accaatccgt tgtccaaaaa tactctcata aaaccattgt cttaacaaat caaaagcagc 19441 taagtcatta tatgaatacg atcaactaat tagagtgcaa aactaaaata accacgggta 19501 atccgggcta ttcagactga aagcctttgt ttaaaggctt ttttgcttgt ttcataacta 19561 atcggcttaa ttaaaagcgt caatccactt ttagtatcat gtctcaattt tcatttgata 19621 gtcagcaagt atatctacaa aattgttaat gattatttct tttgaaagtg ttatattaaa 19681 acataataaa ataataactc ctgaaaagag gctatttatg aaaaaaacaa aacttatttt 19741 ttctttgact tcaatattca ttgcaataat ttctcgtcct gtgtttggat tagaagtaga 19801 taataattcc cttctaagga atatctatag tacgattgta tatgaatatt cagatatagt 19861 aattgatttt aaaaccagtc ataacttagt gactaagaaa cttgatgtta gagatgctag 19921 agatttcttt attaactccg aaatggacga atatgcagcc aatgatttta aaactggaga 19981 taaaatagct gtgttctccg tcccatttga ttggaactat ttatcaaaag gaaaagtcac 20041 agcatatacc tatggtggaa taacacccta ccaaaaaact tcaataccta aaaatatccc 20101 tgttaattta tggattaatg gaaagcagat ctctgttcct tacaacgaaa tatcaactaa 20161 caaaacaaca gttacagctc aagaaattga tctaaaggtt agaaaatttt taatagcaca 20221 acatcaatta tattcttctg gttctagcta caaaagtggt agactggttt ttcatacaaa 20281 tgataattca gataaatatt ctttcgatct tttctatgta ggatatagag ataaagaaag 20341 tatctttaaa gtatacaaag acaataaatc tttcaatata gataaaattg ggcatttaga 20401 tatagaaatt gactcctaat tcaatttttc aatataactt ttatacacta agctattcca 20461 aatagattga atcctctaaa aagtaagtat gtcttttttt atatcactta ggttttgttc 20521 taaatttgtt ctagaatgct atactttcta tattaatttt aaaaaacaaa aattgataaa 20581 ttccttgata atactagcca tttttgttta taaattttct ttattatgct ttttctactt 20641 gtagggggta tgatacaaaa atgaagaaag cttttagaac gtagacagac ccaatgtgat 20701 gctcaaaaag catgaactac tctgctaatg tgatacccga tttcctattt ctgcgaacga 20761 agtaagccaa gaccaaaaca gatgtttttt cctgtggaga aagtcgctgc cgtccgaacc 20821 acctcaaaaa aagtatcaaa aaagactttt ttcactgtta tttttacctg tattaatggc 20881 tatctgaagt ttttgattcc cttcgtaaac tacaattcct ttatttctta gtgaccagtt 20941 taattctttt tttcatctaa aataagtcat gaaacctctt tatcttttgt taatacatca 21001 acttataaaa aagccctgag tatcttcctg aaaataacaa aaattctaat taaccagtta 21061 aacaattgcc ctcctatttg tttattgcta taatgagatg gagtcgttac tattattatt 21121 tattaattag attagaaata aggagatttg attgtgtcaa aatacctaaa atacttctct 21181 attatcacgt tatttttgac tgggcttatt ttagttgcat gtcaacaaca aaagcctcaa 21241 acaaaagaac gtcagcgcaa acaacgtcca aaagacgaac ttgtcgtttc tatgggggca 21301 aagctccctc atgaattcga tccaaaggac cgttatggag tccacaatga agggaatatc 21361 actcatagca ctctattgaa acgttctcct gaactagata taaaaggaga gcttgctaaa 21421 acataccatc tctctgaaga tgggctgact tggtcgtttg acttgcatga tgattttaaa 21481 ttctcaaatg gtgagcctgt tactgctgat gatgttaagt ttacttatga tatgttgaaa 21541 gcagatggaa aggcttggga tctaaccttc atcaagaacg ttgaagtagt tgggaaaaat 21601 cagatcaata tccatttgac tgaggcgcat tcgacattta cagcacagtt gactgaaatc 21661 ccaatcgtcc ctaaaaaaca ttacaatgat aagtataaga gcaatcctat cggttcagga 21721 ccttacatgg taaaagaata taaggctgga gaacaagcta tttttgttcg taacccttat 21781 tggcatggga aaaaaccata ctttaaaaag tggacttggg tcttacttga tgaaaacaca 21841 gcactagctg ctttagaatc tggtgatgtt gatatgatct acgcgacacc agaacttgct 21901 agtaagaaag tcaaaggcac tcgcctcctt gacattccat caaatgatgt gcgcggctta 21961 tcattacctt atgtgaaaaa aggcgtcatc actgattctc ctgatggtta tcctgtagga 22021 aatgatgtca ctagtgatcc agcaatccgc aaagctttga ctattggttt aaatagacaa 22081 aaagttctcg atacggtttt aaatggttat ggtaaaccag cttattcaat tattgataaa 22141 acaccatttt ggaatccaaa aacagccatt aaagataata aagtagctaa agctaagcaa 22201 ttgttgacaa aagcgggatg gaaagaacaa gcagacggta gccgtaaaaa aggtgacctt 22261 gatgcagcgt ttgatctgta ctaccctact aatgatcaat tgcgagcgaa cttagctgtt 22321 gaagtagcag agcaagccaa agccctaggg attactatta aactcaaagc tagtaactgg 22381 gatgaaatgg caacgaagtc acatgactca gccttacttt atgccggagg acgtcatcac 22441 gcgcagcaat tttatgaatc acatcatcca agcctagcag gtaaaggttg gaccaatatt 22501 acgttttata acaatcctac cgtgactaag taccttgaca aagcaatgac atcttctgac 22561 cttgacaaag ctaacgaata ttggaagtta gcgcagtggg atggcaaaac aggtgcttct 22621 actcttggag atttgccaaa tgtatggttg gtgagcctta accatactta tattggtgat 22681 aaacgtatca atgtaggtaa acaaggcgtc cacagtcatg gtcatgattg gtcattattg 22741 actaacattg ccgagtggac ttgggatgaa tcaactaagt aacgcgttta gttaatacag 22801 cgactttaag tttggagtct gagaaaacaa gatacacaaa actgtgctga tcgtttcctc 22861 ggctcctttt cttatcgatt aaggagattt cattgtgaaa cgtactacca ttattatcat 22921 ctggaaaatc atcagatgta tcacacttat ttttggggta tctgttttga ccttcgtttt 22981 gttaaaacaa tctccagtag atcccgtcat ggcaagtgtc aattatgaca catcactaac 23041 ccctgctcag tacaaagcga ttgctcacca ctatggcttg gataagccag ctctagtcca 23101 atattttatt tggttgaaaa atgtgataca gggacattta gggacctcgc tcgtttatcg 23161 gcaacctgtt agtgatatta ttagatcacg ggcaggtgct tctttcatac ttatgggact 23221 ctcttggatc ttatcgggtc ttattggatt tatcttagga acgttatccg ctttccatca 23281 agggaaatta cttgatcgag ttgtcaggtg gttttcttac cttcagatat cagtaccaac 23341 gttttggatt ggcctcattt ttttattaat cttttctgtc cagttggggt ggttcccgat 23401 tggtatttct tctccgatag gcactttaag tcaagatatt acgttagctg atcggattaa 23461 gcaccttatg ttacctgttt tcacgctaag tattctaggc attgccaatg tcactcttca 23521 tacgagaact aaaatgatgt cggtgctttc tagtgaatat gtcttatttg ccagagcgcg 23581 tggggaaaca cagtggcaaa tttttaaaaa tcattgtctt agaaatgcta tcgtaccagc 23641 tattacactg catttttcct attttggaga attgtttgga ggatctgttc ttgctgagca 23701 agttttctca tatcctggct tagggtctac cctcactgaa gcaggactta aaagtgatac 23761 accgctactt ctagctatcg tgatgatagg gacattattt gtttttgcgg gcaatcttat 23821 tgcggacatt ttaaatagca tcatcaatcc acagttaagg agaaaagtat gatattgaaa 23881 cgtcgaacga tggttttatg gcaactaggt atcgccattt ctctcattct tagtattcta 23941 gccttaaacc tttatttcta taggacgcct ttggaaacca atgcagcttt acgcaacctc 24001 gctccttcct taaaccatct ttttgggaca gatggtttag gtagggatat gtttgtcaga 24061 acgattaaag ggctttattt ctctttacaa gtcggcttat taggtgccct tatgggagtc 24121 tttcttgcga ccgtttttgg agtgcttgca ggtttaggaa atagccttat tgataaaata 24181 atagcctggt tagttgattt gtttattggt atgcctcatt tgatttttat gattctcatt 24241 tcttttgttg ttggtaaagg ggctcaaggg gttatcattg caacggctgt tacccattgg 24301 ccctctctag caaggcttat ccgcaatgaa gtctatgatc taaagaataa agcctttgtc 24361 cagctctcta aaagcatggg aaaaacgcct tattatattg tgaggcatca tatcttgcct 24421 ttgattgctt ctcaaatttt cattgggttt atcctcttat ttccgcacgt catcttgcat 24481 gaagcatcca tgactttctt aggatttggc ctttctgccg aacaaccttc ggttggtatc 24541 attctgtcag aagcagctaa gcatatctct cttggcaatt ggtggttggt ggtttttcca 24601 ggcctttatc ttattttggt tgtcaatgcc tttgatacta tcggagaatc tttaaagaaa 24661 ctcttttacc ctcaaacgga tcatttttag //