LOCUS NC_008818:2 18148 bp DNA linear BCT 23-AUG-2011 DEFINITION Hyperthermus butylicus DSM 5456, complete genome. ACCESSION NC_008818 SOURCE Hyperthermus butylicus DSM 5456, complete genome. COMMENT locus start: 702452; locus end: 720599 FEATURES Location/Qualifiers source 1..18148 /organism="Hyperthermus butylicus DSM 5456, complete genome." gene 0..3111 /gene="" /locus_tag="" /db_xref="702452..705563" CDS 0..3111 /gene="" /locus_tag="" /product="SRSR cluster" /translation="FSFELF*AMSKEKSL*EKHLAILF*VVRAPAADHRV*IVEGDLQ FSFELFREDKDDPLEAIAIGVILQFSFELFPGEHGYRAAALVAKRLAILF*VVHE*GT GVEENYGT*LSCNSLLSCSFLPFGGKVLPPAHFSCNSLLSCSVVTRQQVIVQLCIPKD LQFSFELFRWRGCWAVRPWQV*RLAILF*VVHPLLPAYLPLYD*SCNSLLSCSYVLLP *AQGPGH*NLQFSFELFQQLL*GLRHPHGVLWCLQFSFELFGGERYE*KM*IRILQFS FELFR*DRAAARGVRSR*LAILF*VVPNLRYLNDLPPTIDILQFSFELFR*DRAAARG VRSR*LAILF*VVPNLRYLNDLPPTIDILQFSFELFPGTVTYCLNPTA*HQEGILQFS FELFHYTDDVQYCYSNGSLAILF*VVLVEIVK*GDRHADVLQFSFELFKRGGSEENVD CDGRNLAILF*VVRVVLWVVED*EGEESCNSLLSCSLLGERYIAEICLYLQFSFELFS HGSVFPQNHAFIVRLAILF*VVH*SNHNHWELRSTKEHLQFSFELFQASPHLPAPATP RPQDLQFSFELFLIVGAQGGGGNNAFALQFSFELFWHAGSTTTTE*TSWTLAILF*VV PSSCSAVSTM*RLRCLAILF*VVLARWRWRRRDRKIESLQFSFELFIQLRGTRRAWPL ASCPLQFSFELFQYA*TSLSAG*SPISRLAILF*VVQRMFEERLREMQETIHLQFSFE LFLVES*KKVVSAS**ILQFSFELFLKKDLHEVAHHALACNSLLSCSEPVHPHSGQMG AQRLQFSFELFTGERDGKGRVSDQYTCNSLLSCSSHHSLSTQQERAT*RLAILF*VVH SHRIQRHIHDGMQTLQFSFELFRP*ETRQTTRQPGSGGLQFSFELFTLETPMQR*RH* ALQFSFELFDIPRRPPRDKHTVRLQFSFELFLHLAALQQQGRGVHLQFSFELFKTMSA QRCSSST*SSMTCNSLLSCSKKVGNKWRGVKALACNSLLSCSAS*SLNSATWRAALQF SFELFCT" gene complement(3577..4794) /gene="" /locus_tag="" /db_xref="706029..707246" CDS complement(3577..4794) /gene="" /locus_tag="" /product="ribosomal RNA small subunit methyltransferase B" /translation="MPRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSA ALQAILEPPARYYVRVNVLRADPGTVLDEMRAQGLEVYADEELPEALWLPVRGPVEPR DTGCRLVVDKRAAESIMLGANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAE DYRRAMEEGRGLVAVNVRPRYRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAV IVDMCAAPGGKTSHIYELVRGEARIIAVDHSARKTERMRMELGRLGHTRIEVIRADSR YLDRILGSGVADYVLLDPPCTSLGVIPKIYDRKTLRDVANTAEYQRQFLRAAAKLLKP GGVLVYSTCTMTLMENEENTQYAIEKLGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHR TTGYYIARLRKKP" gene complement(4722..5312) /gene="" /locus_tag="" /db_xref="707174..707764" CDS complement(4722..5312) /gene="" /locus_tag="" /product="nucleic acid-binding protein, PIN domain, Zn-ribbon module" /translation="LPVRAAGEDSPVPGGEEAEDALELVYVLDTTAFIARWPLYAPRG RMYTTSLVLGEVRDPSSREGLELALSLGRVEVRDPSPGSIRRVEKLAARHGLHVSLSR TDLSVLALALELAGEGRRVVVVTDDYSVQNLAALLGLEYRSLRTRGISRVEDYEAVCP ACGYRSRRPGERVCPVCGTPLSRRRTSRRTSGRRPS" gene complement(5240..6052) /gene="" /locus_tag="" /db_xref="707692..708504" CDS complement(5240..6052) /gene="" /locus_tag="" /product="ATP-NAD kinase" /translation="LLRRVAIYARPDRREALELAREAYRRLREAGAEAFYDASIAGLV GGPSTDVRFDDVDGVVVIGGDGTLLRLLQLLGSKTPVLHLVRLGRKAFFFDEEPGEAL DRIGDFVAGHFEVEQRVRLHVEVQGVPVYAFNEAAVLGSGSKILVVRVRAGDDTVYER LEGDGLIVATPMGSTAYSYSAGGPVLYLDLDAVVLTPVNPLDRRYGSVVVPGRPGVEV ELIHATRPAKLIVDGVYEKLLSRGAVVRACLCGPPVRIARYRGVRRLRTPWS" gene 6033..7082 /gene="" /locus_tag="" /db_xref="708485..709534" CDS 6033..7082 /gene="" /locus_tag="" /product="Methyltransferase" /translation="MATLRSNPGPPGNCTLLVTEPRCGETVRAELKKHGLRAKNLRPT SPPARARLPAFPVADTGSARMLREELLSACRGLAELIEAECLHVERVEPPVSYVLVGP VAIVSLDERVRGREREVAEQLLRIPGVRAVYGKEATEGEYRVQRLVHLAGERLEEVVY REHGLEIPIPLGRVYINPRLATEHMRVAEMTAADDTVLDMFAGWGGFPLVISKLGRAR LVVANDANPWAIATLARALERNRGKLKTPIIPVMADAALLPELLRPVFTRIIMNLPHS SKQYLPAALKLCSPRGCTIHLYTVASSPEEAAEGITVGEVARIVKVLDYAPYKYIYRV DLKLEGREKNPSTIG" gene 7486..8655 /gene="" /locus_tag="" /db_xref="709938..711107" CDS 7486..8655 /gene="" /locus_tag="" /product="Single-stranded DNA-specific exonuclease" /translation="MPAGVSQRGCRGRNPINRLRGLEVRVLLLLLSSGSYAHQIVLLR GAAPVDALAWCRSLLDGLGEPLLVHHWDADGIASAALLERIMGWRRRLVPRIGFYSAE AVTGQAPLRGAAGLVVVDYGVPQHLPAAAQALGATSIVYIDHHRAECPGGIACCNPVA LGLGGEDEYPSTSLLLAWLLGAGREHLDLALVGLVSDLPGFTETRWAQLVEELERMQG FGLAELLKAVEAVDSCYPLLDTACIDHAVELLAAKGLAAVLDDPRLMEARRRFRELVG EALRDAEANAIREGAVIATEVAVDALVTPKVGRILAREHPDSVVIVQHWIPNLGKGMV YVRSRKHMVGWIAARARAMGYEAGGKDRVAVIHYYQQSQGGKIVEAVTRMLKDIL" gene 8897..9871 /gene="" /locus_tag="" /db_xref="711349..712323" CDS 8897..9871 /gene="" /locus_tag="" /product="Methionine synthase II (cobalamin-independent)" /translation="MAVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAM LVGVQAGAGLTYVSDPALAWHDLLRPFVEAWRGVAVGGLARFFDNNFFYRVPVFTGKP DPKYYVLAKRAVFLSKIAPRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILG EEARRALEAGASVVEVAEPLLGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPS KEVAKELAVLKAQYLALDYADRPETFREAVKIACPEGLAVGAVDARSIYLEPVERVEK ALQTAKELCSPDRLALTTTAPLDLIPQQHAIAKTRHLGHLARRLEEGA" gene 10006..10410 /gene="" /locus_tag="" /db_xref="712458..712862" CDS 10006..10410 /gene="" /locus_tag="" /product="hypothetical protein" /translation="VGGPACFEGSLEELARMYGLELPSSVRGRVTVEGDCGLMNRLGR EIAMVFRAFRSPLSMLNPMNLFRLMSALQEYRRLLKSCCYEEKGRETIVHAVLGDERH VLRVRALLDAGSPLELTALPSLSSLCTRCSSV" gene 10653..11486 /gene="" /locus_tag="" /db_xref="713105..713938" CDS 10653..11486 /gene="" /locus_tag="" /product="conserved crenarchaeal protein" /translation="VPPSVQVYAVPRCGAAGCSARLAGVAAGLELWAEVSPSRSRKKL SQLAGRLHGLADYIDVPDSPMGIPVAHALGVAGFLALRGLRVVANIRLADINANALLS LAGAARLLGVQGLVLLQGDPPVYGKHVGQVSTEYGVKLLRGWEGAEGLRLGVILSLAR GDEELASRLSLPVDFVLATRLWEPGQLDRPPIREARRRGIRVIPYVVVAPENRVGELA KLLSGHQPVFTVEEMLDFVLGLRGLVDGVLVSSPLSHSLLVEALRRLREALGHRSRGT D" gene 11527..12531 /gene="" /locus_tag="" /db_xref="713979..714983" CDS 11527..12531 /gene="" /locus_tag="" /product="Methionine synthase II (cobalamin-independent)" /translation="LAYRVPRAFPVTVVGSYPKMPEALEAIKLRKKGVIGEEEFHERV KPAIRSVVEDYLEAGVDIISDGEQSREDMVVYFAERIQGYEIGDWVRVFDNEYFRKPV VTARLEYVAPMAVMDWEYAQSISQGRPVKAIITGPYTMADWSFDLHYGDRRELVLELA KVLRREIEEFVRRGAQYIQVDEPALPARPRKEEAELVKEALEILFKGVEAKKIIHICY GRIEKLIPYILEFPVDQVDFEFKNSDFKLLPYLKEYGFDKELGYGVIDVHSTRVETVD EIVADVERLMKLDILPPEKIYLDPDCGLKRLPREIAKAKLKNLAEAARRLRKAYGYED" gene complement(12704..13435) /gene="" /locus_tag="" /db_xref="715156..715887" CDS complement(12704..13435) /gene="" /locus_tag="" /product="hypothetical protein" /translation="LSDKIAEEEIAKNPKFIMFNLLRILKFFYSFKELEKMLNIPSQV LWRYTTLRVTPEKETAQKIIAKINELKLIEKAVSKTITGKWELWEIFRNPGILELAAL KIVNEFKKNRIDVVLPAPDPYSIALGSIIAAYLRARLCIPVRMFPPGNSLVEVYMPAP NMLDVAAIPRSCIPRKSKVLIVAATTENQSLIEAAVNLALKSRAEIRGLFSLEGSRDA MRRMLAERGQNDSKILVLVEAAESA" gene 14034..14666 /gene="" /locus_tag="" /db_xref="716486..717118" CDS 14034..14666 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MVIRVLYFASGDLAYGGKLHGLMAGSIFAGRISAVGLELRDCSV LLPGSGRRDARLSGEAYYIDAWRLSELDSRLEGFGARRATVRVEHGDVVLNAETHLAE DCRPATDTAAGRGWVRLLLVLPPRAPPPVQPMAVYLADIAGVSLCSSASRLLCRGGSI ENAAMADVYVELGRLADWLEELGGEPVQVTGRMKPLDLTVFAVAPVAKKV" gene complement(14678..15586) /gene="" /locus_tag="" /db_xref="717130..718038" CDS complement(14678..15586) /gene="" /locus_tag="" /product="pyruvate synthase subunit, porB" /translation="VAVNLRTLPKKRYVLPGTAACPGCPEAMGLRFLGMALGEKAVLV VPAGCTSVIQGLGPKQATNMPILNIVFAASAATASGLSRALKRRGVDAQVVVWAGDGG TADIGFQALSAAAERGEDIIYICVDNEAYMNTGIQRSGLTPYGAWTTTTHTGKRESKK PMPQIVAAHRVPYVATASVGYPWDFIAKLRKAASIRGFKYIHLHAPCPVGWRFDPGLT VHIAKLAVETGAWILYEYENGRLKLNPPSNKLIDPSKRKPVEEYLKLQGRFRHFKPED VQRFKEDIERNWQEIIAILKAQGDLK" gene complement(15606..16826) /gene="" /locus_tag="" /db_xref="718058..719278" CDS complement(15606..16826) /gene="" /locus_tag="" /product="Ketoisovalerate oxidoreductase, alpha subunit" /translation="MGRLMAMRGNDAVAYAVKYARVEVVAAYPITPQTIIVEKIDELI AKGEMDAEMIHVESEHSALAATYGAAVGGVRAFTATSSHGLMYMYEMLWWAAASRIPV VMAVVTRAIGPPWNIHVEHADILATRDTGWLISMSENNQEVFDLTIIMFRVTEDPRVY LPGIVGLDGFILSHTVEPVELPDQETVDAFLPPRRQPYTMEPGKPIAMGNIFPDETFE EMRMDMHRSMLEAKKVIAEVGREYGKLTGRYYDKLVECYRCEDADYIIAGMGSWMGDA KIAADMLREKGIRAGVLRLRWVRPFPWEEVREAAISKKAVIVLDRSVSFGQTGPLFLE LSAALEAKPSMIGVPAGVGGVDISYEDIAAIVEKALAEVEEKGRVYIPSLWYHLGKFY PIMHGEEVLPFPKA" gene complement(16836..17051) /gene="" /locus_tag="" /db_xref="719288..719503" CDS complement(16836..17051) /gene="" /locus_tag="" /product="Ketoisovalerate oxidoreductase subunit vorD" /translation="LRSVFGCYMCWLYCPEHVIEMAAGRGPRGQDIPVIDYEYCKGCG VCAQVCPVKAISMVSEEEFLKKMQEQG" gene complement(17188..17814) /gene="" /locus_tag="" /db_xref="719640..720266" CDS complement(17188..17814) /gene="" /locus_tag="" /product="pyruvate oxidoreductase gamma subunit" /translation="LQRAEGASYIPVLRETLELRFHGRGGQGAVTAATLLVQAALVEG KWGQAIPSFGAERRGAHVLAFARIAPGPVPLHSMVRKPQVLVVLDPGLLAIERDRVLS GFQPGGKIVANLPEPVDLGVHATLYYVNATRIAKELGLVVAGWPVVNTAMLGALARAT GLVSIDSVVEAIKSYWSSSPKIAEANAEAARRAYEETRMVQLAGREVA" ORIGIN 1 ttctcttttg agttgttcta ggctatgtca aaagagaaat cgctataaga aaaacatctt 61 gcaattctct tttgagttgt tcgagcgcct gctgcagatc atagagtatg aattgtcgaa 121 ggagacttgc aattctcttt tgagttgttc agggaggata aggacgaccc gctggaggca 181 atagcaatag gtgtcatctt gcaattctct tttgagttgt tccctggcga acatggttat 241 cgtgctgccg ccctcgtagc caaacgcctt gcaattctct tttgagttgt tcacgagtga 301 ggtacgggcg tcgaggaaaa ctacggtaca tgattgtctt gcaattctct tttgagttgt 361 tcatttttgc cgtttggtgg gaaggttctc ccacctgctc acttctcttg caattctctt 421 ttgagttgtt cagtggtgac aaggcagcaa gtaatagtgc aactctgcat accgaaagac 481 ttgcaattct cttttgagtt gttcaggtgg agaggctgct gggcggtgag gccctggcag 541 gtataaagac ttgcaattct cttttgagtt gttcatccac tcctccctgc ttaccttcct 601 ctttacgact agtcttgcaa ttctcttttg agttgttcct atgtcctcct cccgtaggct 661 caggggccag ggcattagaa cttgcaattc tcttttgagt tgttccagca gttgctctag 721 ggtcttcggc acccacatgg agtgctgtgg tgcttgcaat tctcttttga gttgttcgga 781 ggtgagaggt atgagtagaa aatgtaaatt cgtatcttgc aattctcttt tgagttgttc 841 agatgagata gagcagctgc tagaggagtg cgaagccgtt gacttgcaat tctcttttga 901 gttgttccaa acctgcgcta cctcaacgac ctaccaccaa ctattgatat cttgcaattc 961 tcttttgagt tgttcagatg agatagagca gctgctagag gagtgcgaag ccgttgactt 1021 gcaattctct tttgagttgt tccaaacctg cgctacctca acgacctacc accaactatt 1081 gatatcttgc aattctcttt tgagttgttc ccaggtacgg tgacctactg cttaaacccg 1141 actgcctagc accaggaggg gatcttgcaa ttctcttttg agttgttcca ttataccgat 1201 gatgttcagt actgctacag caatggcagc cttgcaattc tcttttgagt tgttctggtg 1261 gagattgtga agtgaggtga tcggcatgca gatgtcttgc aattctcttt tgagttgttc 1321 aagagaggtg gcagtgagga aaacgttgat tgtgatggaa gaaatcttgc aattctcttt 1381 tgagttgttc gcgtggtgct atgggtcgtc gaggactagg agggcgaaga gtcttgcaat 1441 tctcttttga gttgttccct cctcggagag cgttacattg ctgagatatg cctttacttg 1501 caattctctt ttgagttgtt ctcacatggc tcggttttcc cccaaaatca cgcattcatt 1561 gtacgtcttg caattctctt ttgagttgtt cattaatcaa atcacaatca ttgggagctg 1621 cgatcaacaa aagaacactt gcaattctct tttgagttgt tccaagcatc accgcatcta 1681 ccggctcctg ctacgcctcg gccccaggac ttgcaattct cttttgagtt gttcttgatt 1741 gtaggcgcgc aaggcggtgg tggcaataac gctttcgcct tgcaattctc ttttgagttg 1801 ttctggcacg ctggaagtac tactacaacg gagtgaacca gttggaccct tgcaattctc 1861 ttttgagttg ttccttcgtc ctgttcggca gtatcaacta tgtgaagact gagatgcctt 1921 gcaattctct tttgagttgt tctcgctcgc tggcggtggc gtcgtcgaga tcgcaaaatc 1981 gaatccttgc aattctcttt tgagttgttc atacagcttc gaggaacgcg aagagcctgg 2041 ccgcttgctt cttgtccctt gcaattctct tttgagttgt tccagtatgc atagacaagt 2101 ctatcggcag gatagagccc tatatcaagg cttgcaattc tcttttgagt tgttcagagg 2161 atgttcgagg agcggctgag ggagatgcag gagacgatac acttgcaatt ctcttttgag 2221 ttgttcttag tagaatcata gaagaaggta gtatcagcat cttgatagat cttgcaattc 2281 tcttttgagt tgttcttgaa aaaagacctg catgaggtgg ctcatcatgc gcttgcttgc 2341 aattctcttt tgagttgttc agagcccgtt cacccgcata gcggtcaaat gggagcccag 2401 cgcttgcaat tctcttttga gttgttcacc ggtgagaggg atggtaaggg tcgagtttca 2461 gatcaataca cttgcaattc tcttttgagt tgttcttcac atcattcatt gagtacacaa 2521 caggagagag ctacatagag gcttgcaatt ctcttttgag ttgttcatag tcatcgaata 2581 caacggcata ttcatgatgg aatgcaaacc ttgcaattct cttttgagtt gttcagaccc 2641 tgagaaacga gacagactac ccgccagcca ggctctggag gcttgcaatt ctcttttgag 2701 ttgttcacgt tagaaacccc gatgcagcga taaagacact gagccttgca attctctttt 2761 gagttgttcg atattccacg tagaccacca cgagacaagc ataccgttcg cttgcaattc 2821 tcttttgagt tgttcctaca tctcgctgcg ctacagcagc aaggacgagg cgtccacttg 2881 caattctctt ttgagttgtt caagaccatg agtgcacaac gatgcagcag ttctacatag 2941 tcttcaatga cttgcaattc tcttttgagt tgttcgaaga aggttggcaa caaatggagg 3001 ggcgttaaag cccttgcttg caattctctt ttgagttgtt cagcaagctg aagtttaaac 3061 tctgcaacgt ggagagctgc cttgcaattc tcttttgagt tgttctgcac tgtgggggtg 3121 ttggggtttc tctgttgagt tgggggtccg ggttttctcc cggttttgtg gctgttttat 3181 ttcttttggt ttcctggggg cgtacttgtg gctatggatt tggggttgga atgtgttctc 3241 atggatttgt atgggtttgc atggagcaat gcaagaacac ttgcagttcc gccacgtgta 3301 tgttcgcaag aagacatata tagaattgca agaaactctg acagcaatgg acacccacaa 3361 cacaggatag gagaacatag tgggacaaaa caactagctg taggatgcgc gttgtaaagg 3421 gttctggaac aggtttgcta tgtgttgggt tggtggtgtg ttttgtgggt gggattgctg 3481 tggtgggtgt gttgtggggg ttcagtgccc aaggatttct tcatgccccc ctttctgtgg 3541 gggtctgggg cccatcagtt catcatgggg tgttgggtta tggtttcttg cgtaggcgtg 3601 ctatgtagta gcctgttgtg cggtgtacgt gtgggtggct gcgctgtgcg taccatgcct 3661 ggtttaggcc tctgctgaac ctgtggtatt gtggttcctc cgggtttagg cctagcttct 3721 ctatggcgta ttgtgtgttt tcctcgttct ccattagtgt catggtgcat gttgagtaga 3781 ctagtactcc gcctggcttg agcagcttgg ctgctgcgcg gaggaactgg cgctggtact 3841 ccgcggtgtt ggcgacgtct cggagtgtct tacggtcgta gatcttgggg attacgccta 3901 ggcttgtgca tggggggtct aggagcacgt agtcggcgac cccgctgccg aggatgcggt 3961 cgaggtatct ggagtcagcc cgtatgacct ctatgcgggt gtggccgagc cggcctagct 4021 ccattctcat cctctcggtc ttcctggcgg agtggtctac ggcgatgatc cttgcctcgc 4081 cccttactag ctcgtagatg tggcttgtct tgcctccggg ggctgcgcac atgtccacta 4141 taactgctcc gggctccggg tctaggatcc tggacgcgta catggagggg aggctttgct 4201 cgtagatgac gccccggcgc caccacacgg tgtcccggag gcttggcacc cggtagcggg 4261 gccggacgtt gaccgctacg aggcccctcc cctcctccat tgcacggcgg tagtcctcgg 4321 ctagcacggc gttggcgacg ggtacgccgt tctccgagac tactgtgacc tctgctccgg 4381 ggttggcgca cgcctcgtcc agcgctacga cgccgggggc gtacacgttc gcgcccagca 4441 tgatgctctc ggcggccctc ttgtcgacca ctagcctgca cccggtgtcc cggggctcca 4501 cgggcccccg gaccgggagc cacagggcct ccggcagctc ctcgtcagca tagacttcca 4561 ggccctgggc cctcatctcg tcgagcaccg tgccggggtc agcccggagc acgtttaccc 4621 ggacgtagta cctggcgggg ggctccagta tcgcctggag cgccgcgctt agggctccgc 4681 cgtagaccct gcgcagctcc cgcagcagcc cagcatcata gtctagctgg ggcggcgccc 4741 ggatgtcctc ctggatgtcc tcctcctgga tagcggggtt ccgcacacgg ggcatacccg 4801 ttcacccggc ctccgggacc ggtagccgca cgctgggcag acagcctcgt agtcctccac 4861 cctgcttata ccccgtgtgc ggaggctccg gtactccagg ccgagcagcg cggccaggtt 4921 ctggacgcta tagtcgtcag tgaccaccac gacacggcgg ccctccccag ccagctcgag 4981 cgccagtgcc aggacgctga ggtcggtcct gctgagcgag acgtggagcc cgtgccgcgc 5041 cgcgagcttc tccaccctgc ggatgctccc cggggagggg tcgcggacct cgaccctgcc 5101 gaggctcagc gccagctcca ggccctccct gctagacggg tcccggacct cgcccaggac 5161 gaggctcgta gtgtacatcc tgcccctcgg cgcgtagagg ggccacctgg ctatgaacgc 5221 ggtcgtgtcg agcacgtaga ctagctccag ggcgtcctca gcctcctcac cccccggtac 5281 cgggctatcc tcaccggcgg cccgcacagg caagccctca ccacggcccc gcgggacagc 5341 agcttctcgt agacaccatc cactatcagc ttggccggcc tggtcgcgtg tataagctct 5401 acctccaccc ccggccgccc gggaaccacc acgctcccat accgccggtc tagggggttc 5461 accggggtca acaccaccgc gtccaggtcg aggtagagga cggggccgcc cgcgctgtag 5521 ctataggcgg tgctccccat aggcgtcgca actatgaggc cgtcaccctc aagcctctca 5581 tacaccgtgt cgtcgccggc ccgaaccctc acaaccagta tcttggagcc cgaccccagc 5641 acagcggcct cgttgaaagc gtagaccggc acaccctgca cctcaacgtg gagcctcacc 5701 cgctgctcga cctcaaagtg ccccgcaacg aagtccccga tcctgtcgag ggcctctccg 5761 ggctcctcgt cgaagaagaa cgccttccgg ccgagcctca ccaggtggag caccggcgtc 5821 ttggagccca ggagctggag gagccggagc agcgtaccgt caccgccaat caccacgacg 5881 ccgtccacgt cgtcgaatcg cacgtcggtg ctggggcccc cgaccagccc ggctatcgag 5941 gcatcgtaga aggcctccgc ccccgcctcc ctcaagcggc ggtaagcctc tctagccagc 6001 tccagcgcct ccctacggtc gggcctcgcg tatatggcga ccctgcggag caacccaggc 6061 ccaccaggca actgcacgct gctagtaacg gagccgagat gcggcgagac cgtacgcgcc 6121 gagctgaaaa agcatgggct acgggctaag aacctacgcc ccacctcgcc gccagccagg 6181 gccaggctac cagcattccc cgtagcggat acaggctccg cgaggatgct cagggaggag 6241 ctgctatcag cgtgccgggg cctagccgag ctcatcgaag ccgaatgcct ccacgtggag 6301 agggtggagc cgcccgtctc ctacgtcctc gtaggcccgg tagccatcgt ctcgctggac 6361 gagagggtga ggggccggga gagggaggtg gcagagcagc tgctccgcat ccccggcgtc 6421 cgggccgtct acggtaagga ggctacggag ggcgagtacc gggtccagcg cctcgtacac 6481 ctcgcgggcg agaggctgga agaggttgtc taccgcgagc acggcctgga gatcccgatc 6541 cccctgggca gggtctacat caacccacgg ctagccaccg agcacatgcg cgtcgcggag 6601 atgacagccg cggacgacac cgtgctggac atgttcgccg ggtggggagg cttcccacta 6661 gtaatcagca agctgggcag ggcgaggcta gtagtagcga acgacgccaa cccctgggcc 6721 atagcaacgc ttgccagggc cctggagagg aaccgtggga agctgaagac cccgataatc 6781 ccagtgatgg ctgacgcggc gctgctccca gagctgctaa ggcccgtgtt cacgaggata 6841 atcatgaacc tgccacacag ctccaagcag tacctacccg cagcactgaa gctctgcagc 6901 cccaggggct gcaccatcca cctctacacc gtggcttcga gccccgagga ggcagctgag 6961 gggatcacgg tcggcgaggt agccaggatc gtcaaggtgt tggactacgc cccgtacaag 7021 tacatctacc gtgtagactt gaaactggag ggtagagaga agaacccgtc tacgataggg 7081 taagtggtgg gagcggggcg gggccctgga agccatgcat gcccagcaca gcacccccag 7141 gccctgggcc gggatcagaa ggctgctcga gatgattcta cagcctctcg agctcatggg 7201 agagctggag cgaaggctgc gctgcatcaa gtgggagcag gactgccggt tcctgggccg 7261 caactgtata aggtacaagc taacatgcag cgacaccaag cctctgggcc agctgctcca 7321 agagctacgg gacagtgtta gggagctgct acgctagcag cacatcccag ccctaagcca 7381 gtgcgacgac ctcccggtag gctgcgccga ggcccaggaa ggcctagctc ggattccgac 7441 attcttcatg cagatcgcat agctgtagca agcagctctg ccgggcatgc cggctggggt 7501 gtcccagcgg ggatgtagag gccgcaaccc cataaaccgc ctaagggggc ttgaagtccg 7561 ggtcctcctc ctcctcctct cctcggggag ctatgctcac cagatagtgc tgcttcgggg 7621 tgccgcgccg gtggatgctc tggcctggtg tcgcagcctc ctcgatgggc ttggggagcc 7681 gctgctggtg caccactggg acgctgatgg tatcgcatcg gcggcgcttc tcgagaggat 7741 catgggttgg aggaggcgcc tagtgccccg tataggcttc tacagcgccg aggctgttac 7801 gggccaggcg ccgctgaggg gtgccgctgg gctggtcgtg gtggactatg gcgtgccgca 7861 gcacctcccc gcggctgcac aggccctagg cgcaaccagt attgtctaca ttgaccacca 7921 ccgcgccgag tgccccggcg gcatagcctg ctgcaacccg gtagccctgg ggctaggcgg 7981 ggaggacgag tatccctcca cgagcctcct cctggcatgg ctgctcggtg ctgggcggga 8041 gcacctcgac ctggcccttg taggccttgt cagcgacctc ccaggattca ccgagacacg 8101 gtgggcccag ctggtggagg agctggagag gatgcagggg ttcgggctgg ccgagctgct 8161 gaaggctgtg gaggctgttg actcctgcta ccccctccta gacacggcat gcatagacca 8221 cgcggtggag ctgctggcgg cgaagggcct cgcagccgtt ctggacgacc cgaggctcat 8281 ggaggctcgt aggaggttcc gggaactggt gggggaggcg ctgcgggatg ctgaggcgaa 8341 tgctatacgg gagggagcag tgatagccac cgaggtcgcg gtggacgcgc tggtgacacc 8401 aaaggttggc cgcatattag ccagggagca ccccgacagc gtggttatcg tacagcactg 8461 gataccaaac ctcggcaagg gaatggtgta cgtgaggagc cggaaacaca tggtgggctg 8521 gatagccgcc agggcacgcg ccatgggcta cgaggcgggg ggcaaggacc gagtagcagt 8581 catacactac taccaacaga gccagggcgg gaagatagtc gaggccgtga cgagaatgct 8641 gaaggacatc ctttaggccc cgaaaccccg ggagtactgc agcacgctag gctaaaccct 8701 atgtagctca ggctcgtccg ccctgtgcga gcagcccgga tcaggatggc gagggtttaa 8761 cccctgggcg atgggttgcc gtggggttgc tccgcagcct gccctgctgg ggggctgatt 8821 ggttgtgtgt aacccttttt tagctggttg tcttggcgtg ttgcgggtga ggcttgatag 8881 ctggttggta ggggtggatg gctgtggacg tgtttgtgct tggcggctac tcgcgcggca 8941 ttggtgcacg gaaggttttg agggagtttg aacgcggtgg cgtgggctgg ggcgaggccg 9001 aggctgttat cgggcttgag gaggcaatgc ttgtcggtgt tcaggctggt gctgggctga 9061 cctacgtgtc tgaccctgct ctggcgtggc acgacctgct ccggcccttc gttgaggcct 9121 ggcgtggcgt tgctgtgggt ggtctcgcga ggttcttcga caacaacttc ttctaccgtg 9181 tcccggtgtt tacgggtaag cccgatccga agtactatgt gctcgctaag cgtgcagtat 9241 tcctctcaaa gattgccccc cgcggtgccg gcgtgaaggt cttcatgccc gggccggtga 9301 ccttcgcagc tctctccgat accagcgtgt tcggcggcat ggaggaggct gcaagggaga 9361 tagcacgcat cctcggcgaa gaggccagga gggccctgga ggccggcgcc tccgtggtgg 9421 aggtcgccga gccgttgcta ggcgatatcg atgccaggcc ggagcacgcc gggctcctcg 9481 tggacctcct ctccaagtac ttccccgacc cctcaaagct catcgtatca atctactacc 9541 acccgcccag caaggaggta gcaaaggagc tagcagtgct aaaggcacag tacctcgcgc 9601 tagactacgc tgataggccg gagaccttcc gcgaggcagt aaagatcgcc tgccccgagg 9661 gcctagctgt gggtgccgtg gatgcccgta gcatctatct ggagcctgtg gagagggtgg 9721 agaaggccct gcagacagca aaggagctat gcagcccgga taggctagca ctaacaacga 9781 cagcaccact agacctcata ccacagcagc acgccatcgc gaagaccagg cacctaggcc 9841 acctcgcgag gaggctcgag gagggagcct aggcagccac taccccgccg ccatccccac 9901 atccatgcac cagtgccact gcatagtaga gccatcgtgt acaggcttgg gggtgtacag 9961 caaagcttat actattcaat tcccgatgga gtatctggtg cagggtgtgg gcgggcccgc 10021 ctgcttcgag gggagcctcg aggagctagc taggatgtac ggcctggagc tccccagctc 10081 tgttaggggc cgcgttaccg tggagggaga ctgcggcctc atgaataggc tgggccgcga 10141 aatagccatg gtgttcaggg cgttccgaag ccctctcagc atgctgaacc ctatgaacct 10201 ctttaggctc atgagcgccc tccaggagta ccggaggctg ctcaaaagct gctgctacga 10261 ggagaagggg cgtgagacaa ttgtacatgc agtactaggc gatgagcgcc acgtgctccg 10321 tgtaagagcc ctgcttgatg cgggtagccc gctggagctg acggcgctgc ccagcctctc 10381 gagcctctgc acgcgatgca gcagcgtata gccggcatag tagcgccgcg catccaccat 10441 ggctctaccg tggggcctcc ttgcccggtg ttttcggcag ccaccacccg ccacaagcta 10501 tatcgccgag ccgctaggca gttgcccacg tcaccgctgt agcccgtgac gctcggagtg 10561 ctgcccgccg cggagctagt gttctccgcg cattttatca gtgataaact gttttagagg 10621 tgggaaagct tgattaggcg tattcgggac taggtgccgc ccagcgtaca agtgtacgcc 10681 gtgccccgct gcggggctgc agggtgctca gcaaggctag ctggggtggc tgctgggttg 10741 gagctgtggg ctgaggtttc gccgtcgcgg agccgcaaga agctctcgca gctagccggg 10801 aggttgcacg gcctagccga ctatatcgac gtgcctgact cgcctatggg catacctgtc 10861 gcccatgctc ttggcgttgc cgggtttttg gcgctccgcg gactgcgcgt cgtcgcgaac 10921 ataaggcttg cagacattaa cgccaatgct ctgctctccc tcgccggcgc cgccaggctc 10981 ctcggcgttc aagggctcgt gcttctacag ggcgacccgc cggtctacgg taagcatgtc 11041 ggccaggtct caacagagta tggcgtcaag cttctccggg gctgggaggg cgctgagggg 11101 ctaaggctcg gcgtcatact cagcctcgcg cggggcgacg aggagctagc gtcgaggctc 11161 agcctccccg tggacttcgt cctcgccaca aggctctggg agccggggca gctcgaccgg 11221 cccccgatac gggaggcccg ccggaggggc atccgcgtca taccctacgt cgtggttgcc 11281 cccgagaacc gggtgggcga gttagccaag ctcctcagtg gccaccagcc agtcttcacc 11341 gtggaggaga tgcttgactt tgttctcggg ctccgcggcc tggtagacgg cgttctcgtc 11401 tcctccccgc tctcacacag cctcctcgta gaggccctcc ggaggctacg tgaggcacta 11461 gggcaccgga gtagaggcac cgactaaacc cccctgcatg cggggctgag ggttgagggg 11521 ctaagccttg gcctaccggg tgccccgcgc gttccccgta accgtggtgg gcagctaccc 11581 gaagatgccg gaggctctgg aggctatcaa gctccggaag aaaggcgtta taggcgagga 11641 ggaattccat gaacgggtca aacccgccat aaggagcgtt gtcgaggact acctcgaggc 11701 cggcgtagac ataatcagcg acggggagca gagcagggag gacatggtag tatacttcgc 11761 cgagaggatc cagggctacg agatagggga ctgggtccgc gtcttcgaca acgagtactt 11821 caggaagccc gtggtaaccg caaggctcga gtacgtcgca ccaatggctg tcatggactg 11881 ggagtacgcc cagagcatct cccagggccg cccagtaaag gcgatcatca ccggccccta 11941 cactatggct gactggagct tcgacctaca ctacggcgac cggcgcgagc tggtactgga 12001 gcttgcaaag gtgctccgga gggagataga ggagttcgtc cggaggggcg cccagtacat 12061 ccaagtcgac gagcccgccc tccccgccag gccccgcaag gaggaggctg aactggtgaa 12121 ggaggcgctc gagatactct tcaagggtgt cgaggcgaag aagataatcc acatctgcta 12181 cggcaggatc gagaagctga taccatacat cctcgagttc cccgtggacc aggtagactt 12241 cgagttcaag aactctgact tcaagctact accatacctc aaagagtacg gtttcgacaa 12301 ggagctaggc tacggcgtga tagacgtcca ctcaacccgc gtagaaaccg tggacgagat 12361 cgtagccgac gtcgagcgcc taatgaagct cgacatactc ccaccagaga agatctacct 12421 agacccagac tgtggcctca aacgcctccc aagagagatc gccaaggcca agctgaagaa 12481 cctagcagag gcggcaagga ggctacggaa agcatacggc tacgaggact aatacatggt 12541 ataacaacta gctgcaatcc tctttcaact cttcaggcca gcaaggaatt ccgcaagaag 12601 ctaccctgtt tctgccaaga acccccagcg gtgctgggcc ggaacctcct actacaggga 12661 ggcgcatccc taggctgtgg agataaaagt atgcgctaaa ggctttaggc ggattctgcg 12721 gcttcaacta ggacgagtat tttggagtca ttctgccctc tttcagctag cattctcctc 12781 atagcgtccc ttgatccttc aagcgagaat aggcccctta tctcggcgcg gctttttagt 12841 gcgaggttta ccgcagcctc gattagcgat tggttctccg tggtagctgc tacgattagc 12901 accttagact ttctaggtat gcaggagcgt ggtatggcag ctacatctag catgtttggg 12961 gctggcatgt atacctccac aaggctgttg cctggcggga acatgcgtac gggtatgcac 13021 agtctagccc tcaaatacgc agctataatc gaccccaacg ctatagagta gggatcgggg 13081 gcggggagca ccacatctat cctattcttc ttaaactcgt taacgatttt taatgcggca 13141 agctcgagta tgccggggtt cctgaagatc tcccatagct cccacttacc tgtaatggtc 13201 tttgagacgg ccttctctat tagtttcagc tcatttattt tcgcgattat cttttgtgct 13261 gtctctttct cgggtgttac tctcaacgtg gtatatctcc acaatacttg ggatggtatg 13321 tttagcattt tctctagctc tttaaaagag tagaagaact tcagtatccg aagcaggtta 13381 aacattatga acttagggtt ctttgcaatc tcttcctcag ctatcttatc agacaaactc 13441 ccacaccctc accagcaccc taagcaatga cggggttaaa acaaggttca acgatgcacg 13501 tacaagtagc atatagtaca atacaactcc acctaccagg tgtagcatca caacatgcta 13561 ctccaagcta ggcgcctcga tctagccaca acattgtagt gatacacgct aggatatagc 13621 gctccagtag acatagagaa atccggccga gaggcaggtg ggcagaatgg caaagggcag 13681 aaaagagggc aagaagggaa agggtaagaa gcaggagcag cagcagggta gttagatccc 13741 taagggtaac tggtggctga gacagctaca ccaggcctag gaggttttta aggcgaatta 13801 ttctctatgc atgcgggtct cccagcgctt cgagctgttg accgcaggag ggctggtacc 13861 actaaacaat aaatggtctg gcactgcgtc gtagcggaaa cctagctaga tgctgggccg 13921 ggatggtatc cttattagtt tggctaggct tgcttctgct ccgagtacac gggtactagg 13981 gagctacgcc atagtgttgc tgtttacgat gccttgcatg gagtgtgtag gggtatggtt 14041 atccgtgtac tgtattttgc ttccggagac ctggcttatg gtggtaagct tcacggccta 14101 atggctggca gcatttttgc tggtagaata tctgctgtag ggcttgagct gcgtgactgt 14161 agcgtgctgc tgccgggcag tggacgccgt gacgctaggc ttagcggcga agcatactat 14221 attgatgcct ggcggctcag cgaactcgac agcaggcttg aaggttttgg cgcacgccgc 14281 gcaacagtac gtgtagagca tggcgatgtc gtgctcaacg cggagacgca cctagccgag 14341 gactgcaggc ccgccacaga cacagcggct gggcgggggt gggttcgtct cctcctcgtg 14401 cttccgccca gggctccgcc acccgtgcag cccatggctg tctacctggc tgatattgct 14461 ggcgtatcgc tctgtagcag tgctagccgc ctcctctgcc gtggaggcag tatcgagaat 14521 gctgccatgg ctgatgtcta tgtcgagctt ggcaggctag ctgactggct cgaagaactt 14581 ggcggggagc ctgtacaggt gacgggtagg atgaagccgc tcgacttgac cgtgttcgcg 14641 gttgcgccag tggcgaaaaa agtgtagtgt gtggtggcct actttaggtc tccctgtgcc 14701 ttcagtatcg ctattatctc ctgccagttc ctctcaatat cctccttgaa cctctgtacg 14761 tcctctggct tgaagtggcg gaagcggccc tgcagcttga ggtactcctc caccggcttc 14821 ctcttcgacg ggtctatgag cttgttgctt ggcgggttga gtttgagcct gccgttctcg 14881 tactcgtaga gtatccaggc gcccgtctcc actgctagct ttgctatgtg gactgttagc 14941 ccggggtcga atctccagcc caccgggcac ggggcgtgga ggtgtatgta cttgaagcca 15001 cggatgctcg ccgccttcct cagctttgct atgaagtccc atggatagcc aacactcgcc 15061 gtggctacgt atggcaccct atgcgcagct actatctggg gcatcggctt cttcgactcc 15121 cgcttgccgg tgtgggtcgt ggttgtccag gcgccatagg gtgtcaagcc gctcctctgg 15181 atgccagtgt tcatgtaggc ctcgttgtcc acacagatgt atatgatgtc ctcgcccctc 15241 tccgccgcag cgctaagcgc ctggaagcct atgtcggccg tgccgccgtc gccagcccac 15301 accaccacct gggcatcgac gcctctcctc ttcagtgcgc gggagagccc gctggctgtg 15361 gcagcactag cggcgaagac tatgtttagt atcggcatat tcgttgcctg ctttggtccg 15421 aggccctgga tgacggatgt gcagcctgct gggacgacca ggacagcctt ctcgcccagg 15481 gccatgccga ggaagcgtag ccccatagcc tctgggcagc cggggcacgc cgctgtacct 15541 ggcagcacat acctcttctt gggtagcgtc ctcaagttaa cagccacgcg ggttcacctc 15601 cacactctag gcctttggga agggtaaaac ctcctcgccg tgcatgattg ggtagaactt 15661 gcctaggtgg taccagagcg atggtatgta gacccggccc ttctcctcga cctccgctaa 15721 agccttttcg acaatagcag ctatgtcctc gtatgatatg tctacgccgc cgacgcctgc 15781 aggcacacct atcatgctgg gcttggcttc tagggccgcg ctaagctcta ggaatagcgg 15841 gcccgtctgg ccgaaggata cgctgcggtc caggactatc acagccttct tcgatatcgc 15901 tgcctctctc acctcctccc aggggaacgg cctcacccaa cgcagccgga gtacgccggc 15961 acggataccc ttctcccgta gcatgtccgc tgctatcttg gcgtcaccca tccaggagcc 16021 catgccagcg attatgtagt cggcgtcctc gcaccggtag cactccacca gtttgtcgta 16081 gtacctgccg gtgagcttgc catactccct gccgacctca gctataacct tcttcgcctc 16141 tagcatgctg cggtgcatgt ccatcctcat ctcctcgaat gtctcgtcgg ggaatatgtt 16201 gcccatcgca atcggcttac cgggctccat ggtgtatggc tgcctcctgg gcggcaggaa 16261 cgcgtcaaca gtctcctggt cgggcagctc cacgggctcc acggtgtggc tgagtatgaa 16321 gccgtcaaga cccactatgc ctggcaggta gacccgcggg tcctcggtga cacggaacat 16381 tattatcgtg aggtcgaata cctcctggtt gttctcgctc atcgatatta gccagccagt 16441 atccctcgta gcgaggatgt ccgcgtgctc aacatggatg ttccatggcg ggcctatggc 16501 cctggttacg acggccatta ccacgggtat cctgcttgca gctgcccacc agagcatctc 16561 gtacatgtac attaggccgt ggctggacgt tgcagtgaac gctctaacac cacccacggc 16621 tgcgccgtag gttgctgcta gggcgctgtg ctcgctctcc acgtgtatca tctcggcgtc 16681 catctcaccc ttcgctatta gctcatctat cttctccacg atgatggtct gcggcgtgat 16741 agggtatgct gcgacgactt caacgcgggc gtattttact gcataggcta cagcgtcgtt 16801 gccacgcata gccatgagcc tacccatagc cagggatcac ccctgctcct gcatcttctt 16861 gaggaactcc tcctcggaaa ccatgcttat ggccttcacg gggcagacct gggcgcatac 16921 accgcagccc ttacagtact cgtagtctat cacgggaatg tcctggcctc gcggccccct 16981 ccccgcagcc atctctatca cgtgctcggg gcagtagagc caacacatgt aacagccaaa 17041 cacacttctc aacgtttact actggtctct cagtcctcca cgtaccagtc ctacccatgg 17101 cacccggcga gcccgttgag aggggcagcg ggtgccccgc cggatccacc acggctacga 17161 gcccactcct gcgggccccg gacacggcct aggccacctc cctccccgcg agctggacca 17221 tgcgtgtctc ctcgtaggcc ctcctcgccg cctcagcgtt cgcctcggcg atctttggac 17281 tagagctcca gtacgacttt atcgcctcga ctacagagtc tatggagacg aggcccgtag 17341 ccctcgccag ggcgccgagc atcgctgtat tcaccaccgg ccatccggcc acgaccaggc 17401 ctagctcctt ggcgatacgg gtagcgttaa cgtagtagag cgtggcgtgc acacccagat 17461 ccacgggctc ggggagattc gctactatct tgccgccggg ctggaacccg gagaggaccc 17521 ggtccctctc aatggcgagc aggccgggat caagcactac taggacctgg ggcttccgca 17581 ccatgctgtg cagcggcacc ggccctggag ctatcctggc aaatgctagt acgtgggctc 17641 cacgcctctc agcaccaaag ctgggtatcg cttggcccca cttaccctca acaagagctg 17701 cctgaaccag cagtgttgca gcggtaacag cgccctgccc gccacgccca tggaaccgca 17761 gctccaaggt ttccctcaga accgggatgt aggaggcacc ctctgcgcgt tgcaacctgg 17821 acacgctctc ccaagaagat attccattca tgatggaaca ttttatacat agctaaatgc 17881 ataacagaac tgttaccagg gtggcccgtc agtaccacga ctagccatct tgcaactcct 17941 cccgctgtat gccataggcc ctctacagac cacagcgccc ggctagcagc ttgcaaatac 18001 gagctgagac ttcacgccat actgtggcat gcgagcccca gccgaggcag cagcgtgaaa 18061 gccaacgcca cacatcccat acgcaaacag cagcatccag cagctatgcc agctgcgagg 18121 aagctacacc ctcaccaacc ataactat //