LOCUS NC_008563:28 18420 bp DNA linear BCT 05-OCT-2011 DEFINITION Escherichia coli APEC O1, complete genome. ACCESSION NC_008563 SOURCE Escherichia coli APEC O1, complete genome. COMMENT locus start: 4905186; locus end: 4923605 FEATURES Location/Qualifiers source 1..18420 /organism="Escherichia coli APEC O1, complete genome." gene complement(0..1529) /gene="yjgR" /locus_tag="yjgR" /db_xref="4905186..4906715" CDS complement(0..1529) /gene="yjgR" /product="predicted ATPase" /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTDKTVTLQKLA ESLSEIGVPVFMADVKGDLTGVAEEGTSSEKLLARLKNIGVNDWQPHTNPVVVWDIFG EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAV KAAAQTMRANPTFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE DERNGLINHSPVYGKYEDDVDRESAYEMLQKGFQASIEQQNNPPAKGKEVAVDDGILG GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGEKKVSQVRFVF A" gene complement(1607..2605) /gene="idnR" /locus_tag="idnR" /db_xref="4906793..4907791" CDS complement(1607..2605) /gene="idnR" /product="L-idonate regulatory protein" /translation="MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIM EEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSVHNYQTIIANYN YDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV GFDNRQAAFDMVCTMLDKRVRRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNP RAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFH GLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL" gene complement(2672..3991) /gene="idnT" /locus_tag="idnT" /db_xref="4907858..4909177" CDS complement(2672..3991) /gene="idnT" /product="L-idonate and D-gluconate transporter" /translation="MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQ AVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALV ITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGP TAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEE MPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFT LGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGQYISHLMTGTTL SPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASH VNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH" gene complement(4056..4820) /gene="idnO" /locus_tag="idnO" /db_xref="4909242..4910006" CDS complement(4056..4820) /gene="idnO" /product="gluconate 5-dehydrogenase" /translation="MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAE RAELAVEKLNQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPF TEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAA SKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARW GDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV" gene complement(4844..5875) /gene="idnD" /locus_tag="idnD" /db_xref="4910030..4911061" CDS complement(4844..5875) /gene="idnD" /product="L-idonate 5-dehydrogenase" /translation="MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDL HYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSKLHEGQTVAINPSKPCGHCKYCIEH NENQCTEMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIH AAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVL VNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPM MTLIGKEISLKGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKT QAAKVQLVF" gene 6092..6655 /gene="idnK" /locus_tag="idnK" /db_xref="4911278..4911841" CDS 6092..6655 /gene="idnK" /product="thermosensitive gluconokinase" /translation="MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNID KMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHF LWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQDDEQDIVRIDINHDIANVTE QCRQAVLAIRQNRICAKEGCASDQRCE" gene complement(6659..7720) /gene="yjgB" /locus_tag="yjgB" /db_xref="4911845..4912906" CDS complement(6659..7720) /gene="yjgB" /product="putative oxidoreductase" /translation="MLYTSQTTPEKDQKMSMIKSYAAKEAGGELEVYEYDPGELRPQD VEVQVDYCGICHSDLSMIDNEWGFSQYPLIAGHEVIGRVVALGSAAQDKGLQVGQRVG IGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIES AGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAK EQEVLAMGADKVVNSRDPQALKTLAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVG AVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDA IQHVRDGKARYRVVLKADF" gene 8767..10683 /gene="" /locus_tag="" /db_xref="4913953..4915869" CDS 8767..10683 /gene="" /product="hypothetical protein" /translation="VLRISSIYYNRFSVQTEVEYNNTFKKCINELVNSFPDNIELISE FESQCKIMHDINNSFFAATKCAGIWRKNTKKSHALILNLIMFCEMFLSSLSSLVVVND PKKMKRIFPLFIVSENINIHAEPDIECFRVIDRAFDEVANYTGRIFSYLRTHGPLKLT SCVNKQTLLSMGGYLNEWNVFDSLSRVRDFFRLSSAVFTKLDNNIYSLEVDSFCLYRD YEIARNRLMMRASHLYSEVHEFSNKHFHLNSWVKDHMPSYLNSDGVFSSFHLSELENM SPDDLHEEYGNISLFNWVHAYQCLVELSKEEMSKRFSSTKPIPLQLDRWLIIKSRESW LSFFQRKGIAADAAKKLIDYFTFNSKSHDLNDCPFIPCMDGLCLMPALIANSSVTRSL MSLFGSKKISQASKGRFHEQQFIKRVRDAGIKASPIDAHANYQCDCVILLDDCLIFTE LKSNGQPIYYGKYYQQVCNIVGDSSLIHDHNNKFMRSYFQQINRISEHYLNHLDVIIK EFELPSTWQPKGVYKLIVTTTMLGGKYHVDDTYVADKYALSSFFQRIPGVIYQTNENG KMAKNIIDGFECCEGEITIDKFIDYLSSLPSINAVRKNIKKLTYSVRFNEKLVHHPYY DSWAFGPYIRKGND" gene complement(11306..12211) /gene="" /locus_tag="" /db_xref="4916492..4917397" CDS complement(11306..12211) /gene="" /product="hypothetical protein" /translation="MIAIISLPGISMASSKSLQQAIANIKIWHKGEQRAPHKPLLLLY VLAGYLNGHPRLFDYGSEIYEPLHSLLERFGPQRSQYRPDMPFWRLQGDGFWQLRNAE LCSTAGSSRQPPVKELTEHRVAGGFDEQHYALVTGNKKLINTLAQQILEAHFTESIQE EIADELGFDLQQIRKQRDPLFRKNVLRAYKYQCAICGFNMRHDDTTVALEAAHIKWKQ HGGPCEIPNGLALCAIHHKAFDKGSIGLDENMRVLVSDAVNGGGIVERLFWDFDGKTI TLPQVRKNYPFEGFVEWHRKEVFRG" gene complement(12390..13370) /gene="yjhS" /locus_tag="yjhS" /db_xref="4917576..4918556" CDS complement(12390..13370) /gene="yjhS" /product="hypothetical protein" /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDKEDAPHPRIKQL ARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK LLPFIPDNAGVLIVPCCRGGSAFTAGSEGTYSEPHGASHDACRWGSDTPLYQDLVSRT RAALAKNPQNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVDAFRRALKQYHSQLNKIT DAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGERGLTNVPDEDPD DLSTGYYGSAYRSPENWTTALRSSHFSAAARRGIISNRFVEAILQFWRER" gene complement(13435..14649) /gene="yjhT" /locus_tag="yjhT" /db_xref="4918621..4919835" CDS complement(13435..14649) /gene="yjhT" /product="hypothetical protein" /translation="MTTLTVRVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTITAL TIIMASFATNASVLPETPVPFKSGTGAIDNDTVYIGLGSAGTAWYKLDTQAKDKKWTA LAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHA PMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTTIDKINAHYFDKKAED YFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFE LDFTGNNLKWNKLAPVASPDGVAGGFAGMSNDSLIFAGGAGFKGSRENYQNGKNYAHE GLKKSYSADIHLWHNGKWDKSGELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVL ISVKDNKVTVQN" gene complement(14561..15286) /gene="yjhA" /locus_tag="yjhA" /db_xref="4919747..4920472" CDS complement(14561..15286) /gene="yjhA" /product="hypothetical protein" /translation="VKYMKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYET RLKVSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGML THFSSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYV TYHINSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDR QGVYNGRDNLSENSYRIGVSFKL" gene complement(16076..16483) /gene="" /locus_tag="" /db_xref="4921262..4921669" CDS complement(16076..16483) /gene="" /product="hypothetical protein" /translation="MQLILSIYHVICSVTSKINIKNSAKFNICSTIRLTYDIISQLHL PQNGYFMERSNFLVAIIMLMLRSLAIIPAWFVSLRHEIVTFLFQTVYFLEIWGNAGDA FSSTFVGKYGFGHCDLNLPQSQLFAGRYGKQPI" gene 16743..17345 /gene="fimB" /locus_tag="fimB" /db_xref="4921929..4922531" CDS 16743..17345 /gene="fimB" /product="type 1 fimbriae regulatory protein FimB" /translation="MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIH GFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEIQALKNWLSIRTSYPHA ESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL" gene 17823..18419 /gene="fimE" /locus_tag="fimE" /db_xref="4923009..4923605" CDS 17823..18419 /gene="fimE" /product="type 1 fimbriae regulatory protein FimE" /translation="VSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL GHRNIRHTVRYTASNAARFAGLWERNNLINEKLKREEA" ORIGIN 1 tcaggcaaag acaaatcgca cctggcttac cttcttctcc ccccccagca aactccccaa 61 catcccgcgc acaatctgat tcgtcacctg gcgggcggcg ctttttgcca ttgtttgcac 121 cacaccatct ttcttcccgc cgcgtggtcc ggtagtgcca aacaaaatat ccttcaatcc 181 accgagaata ccgtcatcca ccgccacctc tttccctttc gcgggaggat tattttgctg 241 ctcgatactg gcctgaaagc ctttttgcaa catctcatag gcggattccc ggtccacgtc 301 atcctcgtac ttgccataca ccggggagtg gttaatcaag ccattgcgct catcttccgt 361 caccggcccc attcgtgaac agggggcaat caccatcgcc cgttccacca ctgaagggct 421 tcctttcgca tcgagaaacg agattaacgc ttcgcccgtc cccagttcct ggattgcctt 481 ttcggtatca aatgttggat tggcccgcat ggtttgcgcc gctgccttca ctgctttctg 541 atctttaggc gtaaaagcac gcaaagcgtg ttgaacgcga ttaccgagct gcccgagcac 601 gttatccggg atatctgacg ggttttgcga aacgaaccag acgcccacgc cttttgagcg 661 aataagcctt atcacctgct caatcttatc cagcagtacc tgcggtgcat cgttaaacag 721 cagatgcgct tcgtcgaaga aaaacaccag ttttggtttc tccagatcgc ccgcttccgg 781 caattgttca tacaactctg aaagcatcca cagcaggctg gcggcgtaca gtttcggcat 841 ctggtagagc ttctcggcgc tgaggatatt gataacgcct ttaccgttgg catcggtgcg 901 catccagtct ttgatatcca gcatcggctc accaaagaag tgtgctgcgc cttgctgttc 961 cagcgacaac agcccgcgct ggatggcacc aaccgatgca ctactgatat taccgtactg 1021 attctggaag gatttggcgt tatcgccgat gtactgggta attgcccgca gatctttaaa 1081 gtcgagcagc aacaatccct gatcgtcagc aatgcggaaa atgatattca gcacgccaga 1141 ttgcacatcg ttgagattca acagtcgtgc cagcaacagc ggccccagat ccgaaaccgt 1201 cgcccgcacc ggatggcctt tctcgccaaa gatatcccac accaccaccg gattagtatg 1261 aggttgccag tcatttacgc cgatattttt aagccttgcg agcagttttt ccgaagatgt 1321 accttcctcc gcaactcccg ttaaatcacc tttcacatca gccataaaca caggcacgcc 1381 gatttccgac aatgactccg ccagtttttg cagcgtaacg gttttatccg tccccgttgc 1441 gccggtaatc agcccatggc ggttagccat tcccggcagt aaaaacagtt ctgtgtccgg 1501 cgtgcgggca attaacaggg gttcgctcat gagatttcct ccagtttcct gcctggagta 1561 taggcaacgt ccggcaaaga gaatatgtgt aatgcagaga aaataaccta aagcgtgtta 1621 ccgtgataaa tctgataccc gaggtcaaca gtgttgtggt tgtgatcgtt attcttaatt 1681 ttgctcagca acatttgggc ggccatccga ccaatatcaa aacggggagt aattacgctg 1741 gcgaggcttg ggatcatttg cctgccaatc tccagcccat gaaaacccgc aatggaaatt 1801 tgttctggca cggcgaggtt tcgctcgcgg cacagcagaa gcgcacccat cgcaatatcg 1861 tcattggtgc aaaatacacc gtctaaatcc gggtttgcgc taagggcatc acgcattaac 1921 tgcattccta aatgaatgga tgagatggcg cgtggattca tgcgtaatgg ggaaagatta 1981 tgcagcatca tcgcatcgca atacccctga taacgctgtt catcgcgggt gtcatctttg 2041 gaaccgagat acagaatttt gcgcctgact cgcttatcca gcatggtaca caccatgtca 2101 aaagcagcct gccgattatc aaaaccgacc tccatatcca gccgttctcc ctgtacatcc 2161 atcaattcca cgaccggaat ggtggctgaa cgcagaaatt tcaccgtcct gatggtgtga 2221 tatttttccg aaagaataat cccgtcaatg ttataagaga gcaggttaat caccgactct 2281 tcttcggaat cgcgatcgta attgtaatta gcaataatgg tctgataatt atgcacagag 2341 gtgacggatt ctattcccgc gagaatgtca gcgaagagtt gattttgaaa tgacggaatc 2401 aagataccga gggtataact ttgtgcattc aacaacatgc cgggagcgcg attagggata 2461 taattgatct cttccataat tttggcgatg cgctcgcctg tttcctttgc cacctttttc 2521 ggcgagcgga tataacgact cacggtcatt tttgttacgc cagccagcgt agcgatatcc 2581 tgtaaagaaa ttctgtgatt gcgcataact tctcccaacg tcgggggaat cttcaatctt 2641 cccccgaaac tacatcacaa tattttattc tttcagtgca atacggcgtt aatggctaac 2701 acgcccagca aacccataat agaaataagg gtttccatca ccgtccaggt acgcaacgtt 2761 tcaccaaccg tcagattaaa atacccttta aatagccaga agccagggtc gtttacgtgt 2821 gacgcgatca cgctgcccgc accggttgcc agtaccatta aagcgggatc ggcatgggta 2881 acgttgataa tcggcaacac cacacccgcg gtggtaatgg ccgcgacggt ggcagagccc 2941 agagcgatac gcaacagcgc cgcgacagtc cagcacatca ataacggcga aagtgtagtt 3001 ccggtcatta agtgtgaaat atactgcccg acaccgctat ctactaatac ctgcttaaac 3061 gcgccgccgc cagcgataat aaacacaatc atcgcgatag cgcctataga atccccaatg 3121 atatccatga tttgctcgat ggtgcgtcca ttacgtcggc ccagtgtgaa aatcgcaata 3181 acaatggcaa taaacagcgc aacggcaggg ttaccgacaa attcaaagaa gaggcgcacg 3241 gtgttagttt tcggtaacgt aatttcacaa acggcggcga tagccatcag gatgaccggg 3301 atcacggcag cgaaaatact gttccagaag gagggcatct cctcttcgct aaacagatga 3361 ggattaaata agccttccgg tggtgctttc tcaaagcgag ttagcagttt agaaaacagc 3421 ggtcctgcga caataactgt cggaatggta atgataaatc catacagtaa agtcgttccg 3481 agattagcct caaagatagt cgcgatggca gtaggccctg gatgtggcgg cagaaaacag 3541 tgggttacag agagcgctgc taccatcggt acgccaacat acaacagggg taatccagat 3601 gatgccacga tggtaaatac caacggcaac agcaggacaa agcccacttc aaaaaacatg 3661 gcgaggccca caaccagacc ggtgatcact agcgcccatt gcacgcgttt tttaccaaaa 3721 gtggcaatca gcgtagtggc gatacgttgt gccgcacccg tatcagaaat cagcttgcct 3781 aacatggccc cgaaaccgag gatcattgcc agcccgccga gcgtgctgcc gataccattt 3841 tgtatagagt gcaggacggc ctgtgcatcc atcccttcgg caaatccgac gacggcagcg 3901 accagaacga gggcaataaa gccgttaact ttaaagccga tcatcaggat aagaagcagc 3961 gcgacgcctg ccgcaataat gattaatggc atagtcttta tctcttatta gtgccagaaa 4021 agcagcgctt tcgcgctgca cgtagggtag taggtgttaa acagccacta acatgccgcc 4081 atcaacaaac aacaggtggc cgtttacgaa atcagaggct tttgaagaaa ggaacaccgc 4141 agcaccaatc agttcctgcg gatctcccca gcgtgcggcg ggggtccgtt tgcacaacca 4201 ggcggtgaag gcttcgtcct caaccagtgc tttagtcatt tctgttttga aatagcccgg 4261 cgcaataccg ttgacctgaa tattgtggcg cgccagctcg acgcacatgc cgcgggtgag 4321 catttttacc gcccctttcg atgcggcata aggggtgatg gtgtcacgtc ccagttcgct 4381 ttgcatcgag caaatattaa taactttacc tgccttgcgt tcaaccatgt gacgagttac 4441 cgcttgcgat accaggaaca cggcggtctg gtttactgcg atcacatcat tccactcttg 4501 ttcagggaac tcagtaaaag gatgacggcg ctggataccg gcgttattca ccagcacatc 4561 aatggggccg atgtcctttt cgatatgttc aacggcggca tcaatttcat gtttatgagt 4621 aacattaaaa ggtgcggcaa cggcctgaat accctcctgg ttgagttttt ctacagcaag 4681 ttctgcgcgt tcggcagtaa tatcattaat aattatttgt gcgccatatt tacccaggcc 4741 ggttgccagt aaaaagccaa tgccctgtgc tgaaccggta atcaagatat tttttcctgc 4801 cagtgaaaat agatcgttca ttgtattatt cctttattta tctcttagaa aacaagctgg 4861 acttttgctg cctgggtttt atcaccggcg aaacgtagcg cctcttccag gtctgtgaag 4921 ggatattcag cactcagtaa aggcagtgga ttaataacgc cattcgccag ccatgacact 4981 gcggtattaa attcgctggt aaaacggaaa gagcctttga gtgaaatctc cttaccaatc 5041 aacgtcatca ttgggaattc tgccatcgcg cctcccatcc ctacctgcac cattacgccg 5101 cgtgcacgag tgacctccag acaggtattc actgatgaag gatgaccgga cacttcaaag 5161 ctgacatcga aatagccttt ttccgctttc cagtgatcca tgtcgtcgtt ttgtgggttt 5221 acgagcacat ccgcccccat ctctttgccc agcgaaaggg aacggggact cacatcggca 5281 cagacaattt ccgcggcccc cagtgtttta acagcactga caatcaggca gccaatgggc 5341 ccaacaccag aaataaatac tcgcttgccc tgtaactcgc cggcctgatg tgcggcatga 5401 atcgcgacgg ctaaaggttc ggcaaaagcc ataacctttt cgtcagcttt ggccggataa 5461 gggacacatt gcgacgtttc gaccatttta taacgggtaa agccaccatc aacatgaggg 5521 aaatacatgg cactgccaaa aaaacgcatc tctgtacact gattctcgtt atgttcaatg 5581 cagtatttgc agtgaccgca cggtttagac ggattaatgg ctaccgtttg cccttcatgt 5641 aattttgatg agtcgctatg aataacttta ccgataactt catgacctaa caccatcggt 5701 gcctttatca tgaaattacc tacttttcct tcctgataat aatgtaaatc ggaaccgcaa 5761 attccacctc gggttatttg tactaatgtt ccattattat tccaatctat cgtctgctcg 5821 gtaacggcaa cagttttctt gcccgcaaca acgcaggact gtgttttcac ttgcataaat 5881 tcctcactgg tcaggtagac acctcggaag catttaagcg gttttaattg tcattatttg 5941 tgatgaagat cacgttagaa aattgttaca ttacgatgtt acgcataacg tgatgtgcct 6001 tgtaattctt atcagcagaa ataaaaaaac gtgaaattat tatgccacca ggcgtagtat 6061 cgcagcaggt aagatgattc aggagatttt aaatggcggg tgaaagcttt attttgatgg 6121 gcgtttcagg gagtggtaaa acattaattg gtagcaaggt tgccgcgtta ttatctgcta 6181 aatttattga tggtgacgat cttcatccag ccaaaaatat agataaaatg tcgcagggta 6241 ttccattatc tgatgaagat cgacttccct ggctggaacg cttaaatgat gcttcataca 6301 gtctttataa aaagaatgaa acaggattta ttgtctgttc atcattaaaa aaacagtatc 6361 gtgatatttt acgcaagggt agcccccatg ttcatttcct ctggttagat ggcgactatg 6421 aaactattct cgcgcgaatg cagcgtcggg ctgggcattt tatgccggta gcgttactaa 6481 aaagtcagtt tgaggcactg gagcgtccac aagacgatga acaggatatt gtgcgcattg 6541 atatcaacca tgatattgcc aatgtcaccg aacaatgtcg gcaggctgtg ctggcgatac 6601 gacaaaacag aatatgtgcg aaagagggct gcgcctcaga tcagcgctgc gaatgatttt 6661 caaaaatcgg ctttcaacac cacgcggtaa cgcgccttac cgtcgcgcac atgctggatg 6721 gcgtcgttaa ttttcgacat cgggaacagt tcggtagtcg gcgcaacctt gctgcgggcg 6781 gcaaagcgca tcagcttacg caactcataa ggtgtaccgg tagcagagcc agagacactg 6841 cgatcgcccg caatcagcgt aaaggccgga accggcaacg gcgtgagaac cgcaccgacg 6901 gtgtggaaat taccgccata cgtcagcgcc tcaaaataag gctgccagtc gaggctgacg 6961 ttcacagtat tgataatgag atcaaactgc cccgccagag ttttcagtgc ctgcggatcg 7021 cggctattca ccactttatc ggcacccatc gccagtactt cctgctcttt cgccggattt 7081 gaactaaagg ctgtcacctc gcatcccatt gcgtgcagaa gttttatagc gatatgtccc 7141 agcccgccaa taccaattac cccaacgcgg ctggtagcag tgatatggtg catcaacagt 7201 ggtttaaaga ccgtgatacc accacacagc agcggcccgg cggactcgat atcgatattt 7261 tccggcagtg ggatcaccca ttgccagtct gcacgcaact tctcggcaaa accgccgcga 7321 ttcataattg ttggcaccgc accttgctcg cagttgatct gattaccgct aatacaggca 7381 tcgcaatgcc cgcagctacg cgccgtccag ccaatcccga cacgctgacc gacctgcaaa 7441 cctttatcct gcgcggcgct cccgagcgcc accacgcgac caatcacctc atgcccggca 7501 atcagcggat attgtgaaaa tccccattca ttgtcgatca tcgatagatc ggaatggcag 7561 atcccgcaat aatccacctg cacttcaaca tcttgtggcc tcagctcacc gggatcgtac 7621 tcataaactt ccagttcgcc gcccgcttct tttgcggcat agctttttat catcgacatt 7681 ttttggtcct tctctggtgt tgtctgggaa gtgtagagca tggcagggcg gggtgcctgg 7741 agtgtgacaa aggttacaca tcgcggtatg caatgctgaa aatttcagca cttagcgagg 7801 tgcgagcaag ctggcgcttg catggtggcg tgcgacaggt ataatccaca acgttttccg 7861 catacctctt cagtgccgaa gtggcgaaat cggtagacgc agttgattca aaatcaaccg 7921 tagaaatacg tgccggttcg agtccggcct tcggcaccac accgtatgca aatcgagtcg 7981 ctcaagagcg gctttttttg tgtctgaaat cacccatatc cgtgcagtat ataggcctgc 8041 cagaaaagca gttcagtatt cttcattttg tagtcgatgg tcccaagttt gctctggctg 8101 gaagctgcat cgtccacatt acgtgggcag ggtggtttcg ctatgctact tgaacgtttt 8161 gaccatgtgg ctcaggtagc taatatcaaa agacgtcatt ttgtctccac gcccaccttg 8221 gtgaacattc aataaatagt ttcggtcgag agcagttatg tagggctagc agacgagatg 8281 cgcagacatc ttgttgaaga caattttact gaccacctga gaacgctatt ctaccgaata 8341 atatttatta tcttggtgaa taatgatgat tacctgtgta actatggttt tatgctgatg 8401 ggaccggcag tacaatttct gtagtgtact cgcaatttca ggtctctggc gtttattctg 8461 gtgcaaagga ggtatgtgat gaaaactttg ctaccatgcc attaaatgcg accaatatcg 8521 gattatccat cagttgattg ttgtagattt cattggttat aaaaatgcaa ggtgtaaaag 8581 atgaaattta taattattag ttaagtggct agttttatag taatttagac aataggatgt 8641 atggaaaaat ggaaaaagtt tatgatacca ctagaattag taatcttgct aacgacccga 8701 aacagttttg ttcttttttt gtgagtacat aaaaagagat gatattagta tagatatcgc 8761 cttggatgtg ctgagaatat cttccatcta ttataataga ttttcagttc agactgaagt 8821 tgagtataac aatacattca aaaaatgtat taatgagcta gtaaactcat ttcctgataa 8881 cattgaacta atctctgagt tcgagagtca atgtaaaatt atgcatgata taaataattc 8941 tttctttgcg gctacaaaat gtgctggtat ttggcgtaaa aatacaaaaa aatcacatgc 9001 attaatactt aatctcatca tgttttgtga gatgttttta tcatcattat catccttggt 9061 tgtggtcaat gatcctaaaa aaatgaagag gatttttcca ttatttatcg tttctgaaaa 9121 tattaatatt catgctgaac ctgatatcga atgttttcga gttatcgata gggcatttga 9181 tgaggtagcc aattacaccg gaagaatatt ttcttattta cggactcatg ggccattgaa 9241 actaacttct tgtgtgaata aacaaacctt gctttcaatg ggagggtacc ttaatgagtg 9301 gaatgttttt gactcattaa gcagagtaag agactttttc agactaagta gtgcagtatt 9361 tacaaaattg gataataaca tttactctct tgaggttgat agtttttgtt tataccgaga 9421 ttatgagatt gcaagaaata gactaatgat gagagcgtca catctatata gcgaagttca 9481 tgaatttagt aacaaacatt ttcatctaaa tagttgggta aaggatcata tgccatctta 9541 cttaaattct gatggcgttt ttagctcatt tcatctaagc gagttggaaa atatgtctcc 9601 tgatgacctt catgaagaat atgggaatat atcattattt aattgggtgc acgcttatca 9661 atgtttagtc gagttatcta aagaagaaat gagcaaaaga ttttcatcga caaaacctat 9721 acccctacag ttggatcgct ggctgatcat aaaaagccgt gagagttggt tatcattctt 9781 tcaacgtaag gggattgcag cagatgcagc aaaaaaactg atagattatt ttaccttcaa 9841 ttcaaaatca catgatctta atgattgccc atttattccc tgtatggacg gtttatgctt 9901 aatgcctgca ttaatagcaa atagctcagt gactcgctct ctaatgtcat tatttggttc 9961 caaaaaaatt tctcaagcaa gtaaagggcg atttcatgag caacaattta taaaacgagt 10021 tcgtgatgcg gggattaaag cttctccaat tgatgctcat gctaattatc agtgtgattg 10081 cgtgattctc ctggatgatt gtttgatttt tacagaacta aaatcaaatg gtcaaccaat 10141 atattatggt aagtactatc agcaagtgtg taacatcgtt ggagatagct cattaataca 10201 tgatcataat aataaattta tgcgttctta ttttcaacaa ataaatcgaa tttctgaaca 10261 ttatcttaat catcttgatg tgatcattaa agaattcgaa ctaccatcaa catggcaacc 10321 caaaggtgtg tataagctta ttgttactac aactatgctc ggtgggaaat atcatgtgga 10381 tgatacatat gtagcggata aatatgcatt atctagtttt tttcaacgaa tacctggagt 10441 gatatatcaa acaaatgaaa atggaaaaat ggcgaaaaat atcattgatg ggtttgagtg 10501 ttgcgaaggg gaaatcacta tcgataagtt tatagattat ctttcctctt tgcccagtat 10561 taatgctgta cgtaaaaata taaaaaaatt aacttatagt gttcgattta atgaaaaatt 10621 agtccatcac ccttattatg attcttgggc ttttggtcca tatattcgta agggaaatga 10681 ttagagcaat ttattatata gtccatgtta ttcactgatt atattattga taatataatc 10741 agtgaataac tctaattttt ttaatgttgg ggtttggcct gaagttgaaa ttggtactac 10801 ggaacggtat gatcatatcg catcaaaata tcaaggtagt gatgattttc tacgcgccga 10861 tccagaaacg tggattttat catcaccata agcaatggca gcgacaacac catcaatttc 10921 tatatcaaag gtggtgaaat aaattagaaa attgtttatt taatccatta gcgataagtt 10981 ttattgttat ttagccgaga tatattccat tgaaaaaagt aaattggcac tgatattata 11041 tcaaatggga ataatccttt tgtaaataag ctgaggaatg tgttaattca catccagcgc 11101 cttataaacc gcatcaaccg gttctgagta aaaacttacc tgaaacttgg taaacaactc 11161 tgccggaact gttggaatat ccatagccga ggatatcggc aacagaactc gttttgcgtc 11221 gctatcgaag gcgagttgta aactagtggc aagatcctgc actgattatg tcagcaatat 11281 tgaacatact gcgatagtta tcaacctcac cccctaaaaa cctctttccg atgccactcc 11341 acaaacccct caaaagggta atttttacgc acctgcggca acgtaatagt tttcccgtca 11401 aaatcccaga ataatctctc aacgatccct ccgccgttta ccgcatctga taccagtacc 11461 cgcatatttt cgtccaggcc aatcgatcct ttatcaaagg ctttatggtg aattgcgcaa 11521 agcgccaggc cattaggaat ttcacaagga ccgccgtgct gtttccattt tatatgcgcc 11581 gcttccaacg cgacggtggt gtcgtcgtgg cgcatattaa agccacatat cgcgcactgg 11641 tatttataag cgcgtaatac atttttgcga aataacgggt cgcgctgttt acggatttgc 11701 tggagatcaa aacccagctc gtcagcaatt tcttcctgaa tactctcggt gaagtgcgct 11761 tcgagtatct gttgcgccag ggtattgatg agttttttat tgccggttac cagggcgtag 11821 tgctgttcat cgaaaccgcc tgcaacgcgg tgttcggtca gttccttcac tggcggttgt 11881 cggctgctac ctgctgttga gcaaagctcg gcattgcgta attgccagaa tccgtcgcct 11941 tgtaatcgcc agaacggcat atcaggtcgg tactgtgaac gctgtggacc aaaacgttcc 12001 agtaaactgt gcagaggttc gtagatttcc gagccataat cgaaaaggcg tggatgtcca 12061 ttcaggtatc ccgctaatac gtatagcaat aacaatggtt tatgcggcgc gcgctgttca 12121 cccttgtgcc agatttttat gttggcaatt gcctgctgta gcgatttact ggaagccatt 12181 gatatccctg gcagtgaaat aattgcgatc atgctcgcaa attttctgct gttcaagcct 12241 gcaagcgaag atatattacc ttgatctcat atgttttttt acttcctgtg tgccctaatt 12301 gccatgcgat gttgcaccga cgcaaaccac cgtttacgcc ggagcagtta aaagcgctga 12361 tggatgcgaa taaatcaaat taatgaacgc tcacctttcg cgccaaaact gcaaaattgc 12421 ttctacaaac ctgttagaaa taatccctcg acgggctgcc gcgctgaaat gactgcttcg 12481 cagtgccgtc gtccagttct ccggtgaccg gtacgctgaa ccgtaatatc ccgtgcttaa 12541 atcgtccggg tcttcatcag gcacgttcgt cagtcctctt tcaccttgtt gctggaagtc 12601 gacgaaaata atattggcta aaacattatt ttgataattg ccataaatag cttcatacgc 12661 atgagggaaa ttttctttcc agtaccaggt ggtatcgccg caaaaccacg gcgcgtcagt 12721 aattttatta agctgagaat ggtattgttt tagagcccta cgaaaggcgt caaccatatg 12781 attaaagtgt tgagggtgtg acgcgtagtc actggtcatt aagtcaaatt cgccttgcat 12841 ccagcatacg ccgaggaatt tgttctgcgg attttttgcc agtgcggctc gcgttctgct 12901 gactaaatcc tggtatagcg gagtatccga tccccaacga caagcatcat ggctggctcc 12961 gtgcggttct gaatatgtcc cttcgctgcc cgcggtaaaa gctgatccgc cacggcaaca 13021 cggaacgatg agaacccctg cattatcagg aataaagggc agtaatttcc gtgctatatg 13081 cagtgcctgg ccaacggtgc cgtactgtgt ttgatgattc gttgccagag gatggtgata 13141 accctgcata tcctgaacat cgtgtgggca gtgagtcagt ggaataatgt cgttaaagtg 13201 acatgacggg cctccgggat gtgtatgcgc aaatctcgct aattgtttaa ttctgggatg 13261 aggcgcatct tccttgtccg gtaatggtag tccttcgcca tacgccatgg cattagactg 13321 accagcaacg gtaagaacat agtaataatc gggcgatatt attgcgttca tataattttc 13381 gcgtaataca aatgacaaat tgatagcagg gcccctttac cggggccctg aagcgttagt 13441 tttgtactgt gactttatta tccttcacag aaatcaaaac tgaatccgtc accgctttgc 13501 cgcctgcagt ttcaccgcca ataattaata aactattatt ccagggcaat gatactccgt 13561 aggcccgacc ttgcgataat tcgcccgatt tatcccattt cccgttatgc caaagatgaa 13621 tatcagcgct atatgatttt ttcaggcctt catgcgcata gttcttaccg ttctggtaat 13681 tttctcgtga acctttgaat ccggcccctc cggcaaatat aagtgagtca ttgctcatgc 13741 ctgcaaaacc gccagcgacg ccatctggtg atgcgacggg agcaagctta ttccatttta 13801 aattattacc ggtgaaatca agttcaaata cggcatccgt tcgcaatcct ggtttggctt 13861 cgccattaat aagccaggtt ttatcacctt tattcacaac cgccgcacca gccgttccgt 13921 accagggaga ttcgccagcg taactccatt gctgtgtaga gggatcaaaa gataacagaa 13981 acttattgaa gaaataatct tctgcttttt tgtcaaaata gtgggcgttg attttatcta 14041 tagtggttga atcttttcca gcttcgttga gatcttcaaa atagccattg aagatattct 14101 ggttaacacc gccagtaaca taagccttgc cgttgtgtac aaaagtcaca tggcccgcca 14161 tgcccatcgg cgcgtgcgac atcaatttaa cccagctatt ggttttgggg ttgtatttgt 14221 gtacgtcatt aaatacctga gtcaagccct cgctgttttt gccaatgccg ccaaacacat 14281 acagattgcc atcaataaat gcagaggttg cttgatctct cggtccgcca gggaatgcag 14341 ctaacgccgt ccatttttta tctttggcct gtgtatccag cttgtaccat gccgtacctg 14401 cgctacctaa cccaatgtag acagtgtcgt tatcaattgc tccggtacca cttttaaatg 14461 gcacaggagt ttccggtaat acagacgcgt ttgtggcaaa tgaagccatt atgatagtaa 14521 gcgccgttat tgttttattc attgtgactg tctcctgtct actacagttt aaatgacaca 14581 ccaatgcgat aactgttttc cgataaatta tctctgccgt tgtaaacacc ctgacggtca 14641 aggtagtcat attctatata tggcgtaata tcgggcgtca tatggtattg tagaacaaat 14701 gcattttccg tcgcccattt cttatggttt gcatagcgat aatcgttctg tttgctgtat 14761 agcgtcgttt gccatgcgaa ggtgaaatca ctattaatat ggtaagtgac atatccatcc 14821 caacgatgaa cgttatcacg agacatatca ccggataagt cttgttgtcg gtaagctttc 14881 cagtcgtaac gatagcgaat gccaaaatta agatcttttg tcgcgtccca ggacagtttt 14941 acgtagggtc cgtagcgtgt gccgttgctg ctaaaatgcg ttaacattcc cgggcgcacc 15001 gtccattgat catcaagttt aatcgcgtaa ttaacttcaa cctgaacatc attgagtgcg 15061 gcattttcct ttttattatc atgaatggta ttccaggtat tactttccat acttgcccac 15121 catccatttt gccatccctc actgactttg agtcgagtct cataggcgtg gcttccacta 15181 cgatatccac cacgtacgtc cagtgtcgca gcctgagaaa ttagtggtga cgaaaagcac 15241 agtaataata cgccagaaag tattttagcc tttttcatat atttcactca tttgtaggat 15301 acagaaagca atacaaagcc cgcataaaca attagcattt atgttgtgta atattttttg 15361 ccaggcttat agtgtctttg gcaacgagta gctgtatttt tatatttttt gtataaggtc 15421 tcctgtgaaa attctctttc cacattattt aaataaacag agaaccagat taaatacctg 15481 agtataaaat ctcttctgat gtttaattga tttgaatgtt cgtaagctat atcacttact 15541 caatccattt tacccagagt cataaaatag agtgtctgtt aatctcattt tcatattcct 15601 ttcagactga agtgcgtttt catcacccga tgagaaagaa ctgaagtgat gtttgccata 15661 gattgcgaga tgccctgtct cattgactgt cgcggtgcac ctttatacct gttataccag 15721 atcaaaaatc acgcaatcca tacaacaaaa cgagatttgc aattcgtgtc acaaaatatg 15781 tcgatctttt tctaagagga agatgccatg tgaagccaga cgaacacttg aggtggtctt 15841 caaaaactaa aggcattctt ttaactattt gttttataaa tgatttattt agggtctaaa 15901 caagggaagc tttgcaagct aactcagtga gcgtggtgaa aataagtgtt tacccgccat 15961 caggctgatc ataattctca tcatgaaata tgtttcctgg tttttggctt gtaagtggtc 16021 acccctgaag tcgatctgga aaggcttgta gatgttggtg ttttcaggat gatgtttcag 16081 ataggttgtt tgccgtatcg cccggcgaat agctgtgatt gaggaaggtt taagtcgcag 16141 tgaccaaagc catatttacc aacgaatgta gatgaaaaag cgtctcctgc gttcccccat 16201 atctccagga aatacacagt ctgaaaaagg aatgtaacaa tctcatggcg taagctgacg 16261 aaccaggcag gaataatcgc tagggaccta agcattagca tgataatagc cactaagaaa 16321 ttactgcgtt ccatgaaata gccattttgt ggcaaatgca gttgactaat aatgtcatat 16381 gtgagacgga tagttgaaca aatattaaat tttgctgaat tttttatgtt gattttactt 16441 gttacagaac atatcacatg atatatagat aagattagtt gcattaatga tgagggttat 16501 tattcgattc gtatcagatt gataaatata taaaggtaca tagcatgcaa gagcatggcg 16561 tttgtatggc aaagttatta taagtaacta tcgctactcc atttaagttc actcagaaga 16621 actggtccac ttacgttagt tattaagaaa acgttcgctt ttataaacat aatcaggatt 16681 aaaatgttgg attattgcta acccagcaca gctagtgcgc gtctgtaatt ataagggaaa 16741 acgatgaaga ataaggctga taacaaaaaa aggaacttcc tgacccatag tgaaatcgaa 16801 tcactcctta aagctgcaaa taccgggcct catgctgcac gtaattattg tctgacatta 16861 ctttgtttta ttcatggttt ccgggcgagt gaaatttgcc gattgaggat ttcggatatt 16921 gatcttaagg caaagtgtat atatatccat cgattaaaaa aaggcttttc aacaacgcac 16981 ccgctattga acaaagaaat tcaggcttta aaaaactggt tgagtatccg tacttcttat 17041 ccgcatgctg agagcgagtg ggtattttta tcacgtaagg ggaatccact ttctcggcaa 17101 cagttttacc atattatctc gacttccggt ggtaatgccg ggttgtcact ggagattcat 17161 ccgcacatgt tacgccattc gtgtggtttt gctttggcga atatgggaat agatacgcga 17221 cttatccagg attatcttgg acatcgcaat attcgtcata ctgtctggta taccgccagc 17281 aatgcagggc gtttttacgg catctgggat agagccagag gacgacagcg tcacgctgtt 17341 ttatagagat agttgagata ccagggatgg tgttaaaaac tacattattc ttacgatata 17401 tcaaaaatga ttaaccattt attaattgat gttattgtaa gtatgattct taattataat 17461 aataaacatt aagttaacca tatccataca aaatacaatg gtttatgttc ttcaaaataa 17521 ataaacaaaa tcattcataa atttacacat cacttaaatt cgcctgtttc catacttttt 17581 tctttatttt ttaagcaact ggaagttaat ccactgcaat ctattgttat attgaatcaa 17641 atcaatgaaa atagatgttg tcacatcagt gatattttat ttttgtatga tatttaatgt 17701 aattgactga tagccacatc acttcgggtg tggttatctt tttatctatt gggctaattt 17761 tgaccgattg aggtttccta taggtattca ttcaaatata tctcagtcag gagtactact 17821 attgtgagta aacgtcgtta tcttaccggt aaagaagttc aggccatgat gcaggcggtg 17881 tgttacgggg caacgggagc cagagattat tgtcttattc tgttggcata tcggcatggg 17941 atgcgtatta gtgaactgct tgatctgcat tatcaggatc ttgaccttaa tgaaggtcga 18001 ataaatattc gccgactgaa gaacggattt tctaccgttc acccgttacg ttttgatgag 18061 cgtgaagccg tggaacgctg gacccaggaa cgtgctaact ggaaaggcgc tgaccggacc 18121 gacgctatat ttatttctcg ccgtgggagt cggctttctc gccagcaggc ctatcgcatt 18181 attcgcgatg ccggtattga agctggaacc gtaacgcaga ctcatcctca tatgttaagg 18241 catgcttgtg gttatgaact ggctgagcgt ggtgcagata cccgtttaat tcaggattat 18301 ctcgggcatc gaaatattcg ccatactgtg cgttataccg ccagtaatgc tgctcgtttt 18361 gccggattat gggaaagaaa taatctcata aacgaaaaat taaaaagaga agaagcttga //