LOCUS NC_007929:13 18820 bp DNA linear BCT 22-AUG-2011 DEFINITION Lactobacillus salivarius subsp. salivarius UCC118, complete genome. ACCESSION NC_007929 SOURCE Lactobacillus salivarius subsp. salivarius UCC118, complete genome. COMMENT locus start: 1637261; locus end: 1656080 FEATURES Location/Qualifiers source 1..18820 /organism="Lactobacillus salivarius subsp. salivarius UCC118, complete genome." gene complement(0..1223) /gene="rfaG" /locus_tag="rfaG" /db_xref="1637261..1638484" CDS complement(0..1223) /gene="rfaG" /locus_tag="rfaG" /product="Glycosyltransferase" /translation="LEKVLILTSDSNTGYPVPATKGGAVSELVENIIDSNEKNPVFNF ELVSIYEEKAEKKAKKYNYTKFHWCTPRTIVNSLDKVIFKIAKLLLKERSKSFKSMLA LIQYILFARKILKNNTYDKVIIENTMLLFWTVRGLKKYQGKYYYHAHNLPSTNAFLKK TLLNTTKVLTVSEFVKKRVSAGKTKFPKFDNKKIVVFQNRIDLNNFRILNNFETEKLQ QKFGLNKTDKVILFAGRISWEKGIDKLIDAVKKINSNNIKILIVGSTLHGENKVRKTK YIKKLEDKIHDLNSKIIFTGYISYEIMPVVYNLADIAVLPSMWEEPAGLTPLEAMACG TPVITTDSGGIPEYVGKSAVVLKRNTNLVSDIARNITNLLNDKELYELYRSEGLSRVQ LYNSNNYAEELRKIL" gene complement(1243..2418) /gene="" /locus_tag="" /db_xref="1638504..1639679" CDS complement(1243..2418) /gene="" /locus_tag="" /product="Hypothetical membrane spanning protein" /translation="MYNLLLVIYIILVLLAITNLTEYDRLIYFISTIIFATIGFFFNP IKAFAMGNYLDSYRIFLELDLYREWGWNAGKTLLYRSYNYLGNYDDLPLIKCYWYVVS RFNNNGWLAFINTFLIFTMAYLSINRLAKKLEISGIHKQISATFIFFIIIEDFSRTIA NIRMPLAIAVFTLALAYDVTNDDKKNKIIYWLGYFSTMLLHNSMFMFVIIRVLASLYK KVNIRKIILFIFLIFPIISSGVISIFSKYLSITTVDKINYTMDKGLGGLSGILTLRYG TIIIIIRILISLIMIYELRRINIDSQNSSLGLLVFFSEIVIAFSISSTFLSWNLTNRL SLVLVNLLPLLIIVRKYLANDRKSIFYLNRQGILVWIMAITSMMYYFGTYVYQVLIF" gene complement(2438..3361) /gene="" /locus_tag="" /db_xref="1639699..1640622" CDS complement(2438..3361) /gene="" /locus_tag="" /product="Capsular polysaccharide synthesis protein" /translation="MRIYQIKNKIRKYDFIDIIKKIGIYTYVYPLKLSKKEKELIWRN TVKKDIKKSICFFNDEIIQEPMRQKYIFICWLQGIEKAPYIVQQCVASVKKNSGDFKV IIIDGNNYKEWVDIPDFLIKRWQEGKMLDAWFSDILRLFLLCKYGGLWIDATVYMFDK VPNYIVESNRFMFQSSFLESETTHISNWLIFVKSKNDPFLVGLKNSMVTYLKKKEKPA DYYIFHDFVSVMAVSKEYSKYWKEIPYVNNVNPHMLQYLGNLPYDNSMFNYIKSTSPV QKLTYKLDYNNLKRNTYYDHIFSIDKLKDNY" gene complement(3336..4448) /gene="rfaG" /locus_tag="rfaG" /db_xref="1640597..1641709" CDS complement(3336..4448) /gene="rfaG" /locus_tag="rfaG" /product="Glycosyltransferase" /translation="VKKILIIGMTSGVGGVETFITNIVDKIDQTKFHIDILLFQEPNK KYNEVLNKANKVIRIHAINKEPMRYFIDIIKLYAKENYDIIHLNECSSKLFIYCWPVI FRNNSKLIVHSHNSSDGSIKLHKIMAKIQNVVADKMVACSNEAAVWMFGEATATSGKV QFIKNGIDLNVYKFEKNMRNMYRKKYNLEGKTVLGSVARFERQKNHRRIIDIFEKYHE KNKNSVLVLLGEGSKKSEIEKYVSKKSLKQNVLFLGNRVDVVNWLSTFDVLLMPSLYE GLPFIALEAQACSLPVITSKEISNEVNITTLVDSIPLENSNDVWVKKIDNVLLNEDVR LDLRNKIKNDFKKKGYSLGDTVNVIEEEYENLSNKK" gene complement(4451..5494) /gene="rfaG" /locus_tag="rfaG" /db_xref="1641712..1642755" CDS complement(4451..5494) /gene="rfaG" /locus_tag="rfaG" /product="Glycosyltransferase" /translation="MISIIVPIYNAENSLRECIDSVIYQDYSNIELILVDDGSVDRSY EICKEYKNKDKRIRLHHQSNLGVSSARNKGISMANGEYVFFLDSDDQCENILSYCVSI MKKENIDLLVGGTDYYKNNNFLISENANLFGEEYKIYSDDSKSKLNRWVMERNITDFP ELLVSSRKTIRIGGVAAKLIRKKSMGGLRFIENLGYSEDLVFLYELLKKIDRLVVLNK SIYRYNYREDSATNSGYNPKIIRFNKELSKYIYKISTDYDEVYENSMYEKILEIYWGS IIHGITYNPNSKFYEKLRKISDESKYYNSMLKKLKIHNVRKKKNKLILFLYKNNMSLC IFFLSYIKKIKGE" gene complement(5534..6628) /gene="rfaG" /locus_tag="rfaG" /db_xref="1642795..1643889" CDS complement(5534..6628) /gene="rfaG" /locus_tag="rfaG" /product="Glycosyltransferase" /translation="LNRIMKREKLLFIVEAMGGGIFTYITNLTNELVKKYDVYVAYSV RKETPKDFKKSFNVNVKLIKVENFVRSINILQDLKAYIEIKKIVKKVNPDIIHLHSSK AGVLGRLAFSFFNNKYTVFYTPHGYSFLMSDTSKVKRLVYRNIEKILGMGNAVIISCS PGEDKESQKIAKYTEHVNNGINMKEITNVVGDYKKSNSNKVKVATLGRISYQKNPALF NRIAENMPEKEFIWIGNGELKEEITSPNVRITGWLDRNAALRKLNEADIFILTSRWEG LPMALLEAMYMGKLCIVSDTIGNNDVIKNNVNGFICDSIEDYINAINVSKEKKKELIE HAIDDVKKEYNTITMARKYSEIYDRLKYKK" gene complement(7150..7275) /gene="" /locus_tag="" /db_xref="1644411..1644536" CDS complement(7150..7275) /gene="" /locus_tag="" /product="hypothetical protein" /translation="LTKNQKNLVVFYLKSNPNPQILKWIKEKFGEENVINLGAEK" gene complement(7348..8637) /gene="" /locus_tag="" /db_xref="1644609..1645898" CDS complement(7348..8637) /gene="" /locus_tag="" /product="Transposase ISLasa4t, ISL3 family" /translation="MDNNIKLLLGITDPNLTIDPKYQYTSYIEEKIIKNSKTLLCHLY LSYPMYCPNCKALMLHNGTKVANNVHLSSAGKKLVLSIRKQKYLCPECKKTATAKFKD TNYHDHFSNAVKAKLVRDLSLSRPMCEIAADSFTSSNTIIRSLESVENNFKVNRNWLP SHLSLDDFKSGKRFSSSGMSMCLINAVNHRIIDIIPERNNKFLRNYFIQYSYKARLSV MTITVDLYAPYRSLIKKLFPNAFIIADKFHVVAQAYTAMNKIRTRVMKEYGAGTHEYR ALKRFWKLLLKNQDNVDYHRYYPRINFKYAELSDSEVLDRLSDMSSELKTAYEYYQLL LQMYRKNSCQSLNLLIDTSSWNLPPEMRQALKTIKKHKAEIENSFVLPRLTNGPIEGI NNHIKVIKRIAYGYNNFKHFRLRILLSLKNNVIFFST" gene complement(8753..10444) /gene="" /locus_tag="" /db_xref="1646014..1647705" CDS complement(8753..10444) /gene="" /locus_tag="" /product="DNA helicase" /translation="MDTKIEPEVQRAIECIRSKTNFIMEGGAGSGKTRSLSEVIGEIG QRYPDRRILCITYTNNAVNEIINRVNVKNIVVSTIHKFLWNLIKQFQDEIKWALNELI KEELINKNIPENFDARKLEKITYDDYVSWNRGVISHNEVLSIAKKLFDTKPKLSKIVE GIYSYIFIDEYQDTDKNVVEMFLKNLNNEKVVIGFFGDSMQAIYDRGIGDLNDYNLDR IEKKKNWRNPNAVIKVGNNLRIDKMQQESGKTNNIEGKALFFYGKSEELLKQHPRYQE LKLSDDDFKRLQLTKKSIASAVGFPNLYELYNIDMVINLIKDVKEKNENVEDKTLKEV VKIYCKKRDSWKFKKESYKRFEHKNFKELINQKINRDSLLSFDGNLSNSNPNRDEILK YLDRIYEIITLYEDGKIGEFLTKSKMKIGSISDKNKISESMRKLLDGVNDDNICIGSV VELAKEELEIKTGDNFDKFIKEEGQYLWERIKEIPFKEYKKSIEYLEKKTPYATQHSV KGSEYDNVFVMLESSWQKYSFDGMMLEDGEEPSKRALKLFYVCCTRAQKNWLYNI" gene complement(10429..12468) /gene="" /locus_tag="" /db_xref="1647690..1649729" CDS complement(10429..12468) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MYLNEVKVKNYRSLKDVKLVLDKEKGTPNLSLIIGKNNSGKTSF LKIMKKMIAEDRKLSWDDFNIQYRREIHNILVSKEEGNEEDIEGIILDLYMEYDDNDD LNNILPLMLDLNMENNIVVLEFKCQPIIHKIEELRNLVNDTELKEYRKFSDFMQENLN KYFETNVYARGYDYESHELTDAIEKLDSSIVKKIINITGISAKRDTSNNEKDRTLSQI AAKYYENFSDEEDKIRSLREEVSKTDGILNKEYNKLFKDVIDDFRNFGNFPNGEEDVN IHSKMDVSKLLKGNTVFSYQYDKEDLPENYNGLGYMNLLGIIFEVKACFQKFRQDSNR SKINILYIEEPEAHTHPQLQYVFIKNIGKLIENEKDNLNVQTIITTHSSHIVSQCKFE DTNFFIKEKDNAQIKSYADLENLYKNEKEVFEFVKKYITLSRAEIFFADKLILIEGDT ERILLPTMMERVDNNKNNGKDVPPLLSQNISVLVIGNHAHVLSKLISFLNLKTLVITD IDAKGIKGGKIKNPAEGKITTNGSLKKFFKGKSFKDLRNLGKDKKILSIEVKTEDRGK ENVEYKEDPNGNLRIAYQIKEKNSKEESYQATSFEDSFIHLNLEFVQKLADEHGRNAG LKLVKKLKETKFTPYELSSNCIDSKTNFAIGILMYGNNRWQIPKYIEEGLEWIRK" gene complement(12662..14059) /gene="" /locus_tag="" /db_xref="1649923..1651320" CDS complement(12662..14059) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSENRFCPNCGQKVDAGEKFCANCGYQLSEDVEKVEENKSLESS NPTEVSQSTGQFSRPNNNNYNRPKKPINKKVMIPVVVLVALIGAYIAGNKYYSSQNQL NRFTTALSKSDSDVSGYLTTTEGSKKVPKEEAKAFKKQFSGSQSSIYYMKQSLMSNGS YGNYSWVQSGRRLFVFPAYKLQADPGYAYVSTNNKNVKIYQDGNKIATTKDDSRTVKV GPIYPGKYTFKAQGTVNGEKLSSKKDFYVKSGKDNNVELNLSTATFTVKGMKDSNIYI NDKKVGKLDSDGEKKFTNYPITNGLKLYLTTDVNGKEIKSKQVSVEDKINQGVHTITP GYKGLVSKDEAESLLSSVFSGLRYGASSSTADHFIDGENNDSYNELVDFFKTIEDHLE DVDVVKINSITPLGNNKAEVSYSVKYSFENDDQRKVQQFTYNGAQIEKEDGEYKVKSI GKTGSSPDWERRYDD" gene complement(14084..14920) /gene="" /locus_tag="" /db_xref="1651345..1652181" CDS complement(14084..14920) /gene="" /locus_tag="" /product="Hypothetical membrane spanning protein" /translation="MNKCPNCGSDIKEGAKFCTSCGYQLVQGNVNNTVNTTNTTNVNR ARQTVDTDRMKEVSMSYWDWLVTSWKHPFKVQAGEKYTGLVTLAIEGVMFALSVMILV RKIAGAFVESSNSIMSFFSGGSSSSTSNPVGFNVFVVFFLAVFIAALAIIGAVLLIEK GFSDSNKEYLDLVNEVAHKTSSLVLLNAVLFVYSFIVSNASVNSVVLIDVVLGLMSMI WVIGILSVAFELKETKMDNIYVGLVIYIAHIIIISIAGWIVVNHYAGMLTDVISELIG AI" gene complement(14981..16084) /gene="" /locus_tag="" /db_xref="1652242..1653345" CDS complement(14981..16084) /gene="" /locus_tag="" /product="Beta-N-acetylhexosaminidase" /translation="MRKFLLVVIICLSCIVAFQDKVFAKNISDKKIQKIVNNMTLDEK IGQLYMSPSSGDAAKMTNDIKKYNLGGIVLFGEDFSNQNADTMKQKDANFQNASKYGL FISTDQEGGIVSRLSTSPQLTNGRKFPSPQEVYKQSGMSGVVKEYSSVAEILRNLGIN WDFAPVADVSNDPNSFIYDRTLGQNYQLTAQYVSKVVPAIQKQQVAATVKHFPGYGSA GDTHTGFASDGRSINEFRQNDFLPFKAGIKAKADSVLVGHVVVNNLDATKPASVSKPV HEILRKELKFKGVIITDDMGMGALTSFAQKQHTNIDVMAIEAGNDMLLSNGYVDGIPA IKDAIKRGDISQKQIDNSVKRILRLKAKLNIMK" gene complement(16303..17139) /gene="rfbD" /locus_tag="rfbD" /db_xref="1653564..1654400" CDS complement(16303..17139) /gene="rfbD" /locus_tag="rfbD" /product="dTDP-4-dehydrorhamnose reductase" /translation="MKILITGANGQLGQEMQHLLDERGQEYLAEDSQGLDITDKKAVD AYFEKNKPEVVYHCAAYTAVDKAEGEGKELNWKVNVDGTENIAKACQKVGATLLYVST DYVFDGNRTSGEYLPDDPKGPRNEYGKAKLAGEEAVQKYCDKYYIIRTAWVYGQWGHN FVYTMLNLAKNHDKLTVVDDQIGRPTWTRTLAEFLTYLVDNKIEYGVYHCCNDGQCSW YEFAKEILKDTDVDVQPVTSDQYPTAAFRPHYSVMKLAKETGFVFPDWKEALDEFLSE VK" gene complement(17195..18226) /gene="rfbB" /locus_tag="rfbB" /db_xref="1654456..1655487" CDS complement(17195..18226) /gene="rfbB" /locus_tag="rfbB" /product="dTDP-glucose 4,6-dehydratase" /translation="MFKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKE NLAGLPQDRVELVVGDICDKELVDKLVQNADAVVHYAAESHNDNSLRNPDPFIQTNIV GTSVLIEACTKYDVRFHHVSTDEVYGDLPLREDLPGHGEGRGEKFTPESPYKPSSPYS SSKASSDLLVRAWVRSFGLKATISNCSNNYGPYQHIEKFIPRQITNILSGIRPKLYGT GKNVRDWIHTNDHSSAVWKILNEGKIGETYLIGADGEKNNKEVLELILKLMGQPADAY DQVKDRPGHDLRYAIDASKLRNELGWEPQYTNFEEGLKATIDWYTNHREWWQDQKAAV EAKYAKNGQ" gene complement(18238..18819) /gene="rfbC" /locus_tag="rfbC" /db_xref="1655499..1656080" CDS complement(18238..18819) /gene="rfbC" /locus_tag="rfbC" /product="dTDP-4-dehydrorhamnose 3,5-epimerase" /translation="MGKLIVKETKLQDVKLITPAVFGDNRGFFTESYSDRDFKAAGID FDFIQDNHSLSTQAGVLRGLHFQRGKAAQTKLIRVATGAVLDVIVDLRKGSPTYKQWE GYILSESNHRQLLVPKGYAHGFVTLTDNVNFLYKCDNYYDAEADGGISFKTPELNIDW PIDLDKAITSEKDANQPTLTEFEKGNPFVYGEI" ORIGIN 1 ttacaatatt tttctcaatt cttctgcata attattacta ttatataatt gaaccctgct 61 tagtccctct gatctatata attcatatag ttccttatca tttagtaaat tcgtaatgtt 121 tctagcaata tcacttacta aattcgtatt tctttttaaa acaacagcag atttcccaac 181 atactcaggg attccacctg aatcggtagt tataacaggt gtcccacaag ccattgcttc 241 taacggagtt aagccagctg gctcttccca catagacgga agtactgcaa tatctgctaa 301 attatacact accggcatta tttcatatga gatatatcct gtgaatatta ttttactatt 361 taaatcatga atcttatctt ctaatttttt tatatattta gtttttctta ctttattttc 421 accatgtaaa gtactgccca caattaaaat ctttatgtta ttagaattta ttttttttac 481 agcatcaatc aacttatcta tacctttttc ccaagatatt ctccctgcaa aaagtataac 541 tttatcagtt ttatttaatc caaacttttg ttgtaatttc tctgtttcaa aattatttaa 601 aattctaaaa ttatttaagt ctattctatt ctgaaaaacc actatttttt tattatcaaa 661 cttaggaaac ttagtttttc cagctgacac tctttttttt acaaactcgc taactgttaa 721 tactttagta gtatttaata atgttttttt taaaaaagca ttagtactag gtaagttatg 781 tgcatgataa taatactttc cttggtattt ttttaaccct ctaactgtcc aaaataataa 841 cattgtattt tcaataatga ctttatcata agtattgttt ttcaatattt tcctagcaaa 901 aagtatatat tgtatcagag ctaacataga tttaaatgat ttacttcgct cttttaataa 961 taattttgct atcttgaata ttactttatc taaactatta actatagttc gaggggtaca 1021 ccaatgaaat ttagtataat tatacttttt agcttttttt tctgctttct cctcgtatat 1081 agaaactagt tcaaaattaa aaactggatt tttctcatta ctatctatta tattctctac 1141 taactctgat accgcaccac ctttagtagc aggaaccgga taccctgtat ttgaatcaga 1201 agtcaaaatt aatactttct ccaaaaatat catcctccta acattaaaaa attagaactt 1261 gatatacata tgttccaaaa taatacatca tagaagtaat agccatgatc cacactaaaa 1321 taccttgtct attaagataa aaaatacttt ttctatcatt ggctaaatat ttccttacta 1381 ttattaataa tggtaataaa ttaaccaata ctaacgatag cctatttgtt aaattccagc 1441 ttaaaaaggt actacttata ctgaaagcta taacaatttc actaaaaaag accaacagtc 1501 ccaaactact gttttgtgaa tcaatattaa ttcttcttaa ctcatatatc attattaaac 1561 ttattaaaat tctaataata attattatcg taccatatct taatgttagt attcctgata 1621 aaccacctaa ccctttatcc atagtatagt taatcttatc aactgttgtt atggataaat 1681 actttgaaaa tatactaata acaccactag aaataattgg aaatatcaga aaaataaata 1741 gaattatttt tctaatatta actttcttat ataagcttgc taacacacgt ataataacaa 1801 acataaacat agaattatgt agtaacattg tgctaaaata acctagccaa tatattattt 1861 tgtttttctt atcatcattt gtcacatcat atgctaaagc taatgtaaat acagcaatag 1921 ctaggggcat tcgtatattt gctatagttc tactaaaatc ttctattatt ataaaaaaga 1981 taaaggtagc tgaaatttgc ttatggatgc cactgatttc caattttttt gccaatctat 2041 ttattgataa ataagccatt gtaaatatta aaaaagtatt tataaatgct aaccatccat 2101 tattattgaa tctagaaact acataccaat aacatttaat tagcggtaaa tcatcgtaat 2161 tacctaaata attataactt cggtacaaca aagtcttacc agcattccag ccccattccc 2221 tatataaatc taattctaga aatattctat aactatctaa atagtttccc attgcaaaag 2281 ccttaatggg gttaaaaaag aatcctatag tagcaaatat tatagtacta ataaagtaaa 2341 ttagtctatc atattcagtt aaattcgtaa tagcaagtag aactaatata atatatatta 2401 ctaatagtaa gttgtacata taaaatttaa tacctcactt aataattatc ctttaactta 2461 tctatagaaa aaatatgatc gtaataggta tttcttttta agttattata atctaattta 2521 tatgttaatt tttgaacagg agatgtactc tttatataat taaacataga attatcatat 2581 ggaagatttc caagatactg gagcatgtgg gggttcacat tatttacata tggaatctct 2641 ttccaatatt ttgaatattc ttttgaaaca gccataacgc taacaaagtc atgaaatata 2701 taataatcag caggcttctc tttcttcttt aaataagtta ccatgctgtt ttttaatcct 2761 accaaaaaag gatcgttttt actttttaca aaaattaacc aattagaaat atgtgtagtt 2821 tcactttcta aaaatgaaga ttgaaacata aatctattgc tttctactat atagtttgga 2881 accttatcaa acatgtaaac tgttgcatca atccacaagc caccatactt acacaataaa 2941 aacaatctta gtatatcaga aaaccatgca tccaacattt ttccttcctg ccatcttttt 3001 ataagaaaat caggaatatc aacccactcc ttatagttat ttccatctat aattataacc 3061 ttaaaatctc cagaattttt tttaacagat gctacacatt gttgtacaat atacggagct 3121 ttttctattc cttgtaacca acatataaat atatatttct gccgcattgg ttcttgaata 3181 atttcatcat taaaaaaaca tatactcttt tttatatctt tttttactgt atttctccat 3241 atcaattctt tttctttttt agataactta agtggatata catatgtata tatccctatc 3301 ttttttataa tatctataaa atcatatttt cttattttat tttttatttg ataaattctc 3361 atattcttct tcgataacat ttactgtatc acctaaacta tacccttttt tcttaaaatc 3421 attttttatt ttatttctta aatctaatct tacatcttca tttaataata cattatcaat 3481 tttcttaacc caaacatcat tactattttc taaaggaata ctatctacca atgtagtaat 3541 attcacttca ttagaaattt ctttagaggt tattactggt aatgaacagg cttgtgcttc 3601 tagggcaata aatggcaacc cctcgtataa tgaaggcatt aataatacat caaaagtact 3661 taaccagtta actacatcaa ctctatttcc taaaaataaa acattttgct taagagattt 3721 cttactcaca tatttctcaa tttcactttt tttactacct tcacctagca atactaatac 3781 agaattttta tttttttcat gatatttttc aaaaatatct attattcttc gatgattttt 3841 ttgtctttca aatctagcta cacttcctag aactgtttta ccctctaaat tgtatttttt 3901 tctatacata tttctcatat ttttttcaaa tttatagaca tttaaatcaa taccattttt 3961 tataaactga acttttccac ttgttgcagt ggcttctcca aacatccaaa ctgctgcttc 4021 attagaacaa gcaaccattt tatcagcaac cacattttgt attttagcca taattttatg 4081 aagttttata cttccatcac tactattatg actatgaact attaatttgc tgttatttct 4141 aaatattact ggccaacaat atataaataa ttttgatgag cattcattta aatgaataat 4201 atcataattt tcttttgcat ataattttat gatgtctata aaatatctca ttggttcttt 4261 atttatagcg tgtattctta tgactttatt agctttattt aatacttcgt tatatttttt 4321 atttggctct tgaaaaagta aaatgtctat atgaaacttc gtttgatcaa ttttatcaac 4381 aatatttgtt atgaatgttt ctacccctcc aacgccactt gtcattccta taattaaaat 4441 cttcttcact tctattctcc ctttattttt tttatatacg atagaaaaaa tatgcataaa 4501 ctcatattat tcttgtacaa aaataatatg agtttattct tttttttcct tacattatga 4561 atttttaatt tttttaacat actattatag tatttcgatt catcagatat ttttctaagt 4621 ttttcataga atttactatt aggattgtat gttattccat gaataataga accccagtat 4681 atttctaata ttttttcata cattgaattt tcatatacct catcataatc agtagaaatt 4741 ttatatatat acttacttaa ctctttatta aatctaatta ttttaggatt atatcctgaa 4801 ttagtagcag aatcctcacg ataattatat ctatatatgg atttattaag tactactaat 4861 ctatcaattt tcttcaacaa ttcatataga aaaactaaat cttcactata tcctagattt 4921 tctataaatc ttaaaccacc catgctcttt tttcttatca gttttgcagc aactccacct 4981 atacgaatcg ttttcctact tgatactagc agctcaggaa aatcagtaat attcctctcc 5041 attacccaac gattcagctt gcttttacta tcatccgaat atattttata ctcctcacca 5101 aacaaattag cattctcaga tattaaaaag ttattatttt tataatagtc tgttccccct 5161 actaataaat caatattttc ttttttcatg atacttacac aatagcttaa tatattttca 5221 cattggtcat cactatctaa gaaaaataca tattccccat tcgccatact tatccctttg 5281 tttctagcac tggaaacccc caaattagat tgatgatgta atcttattct tttatcttta 5341 tttttatact ctttgcaaat ttcataactt ctatcaacag atccatcatc tactaaaatc 5401 aattctatgt tggaataatc ttgatatata acactatcaa tacactctcg tagactattt 5461 tcagcattat atattggtac aataattgat atcatatctt taaccatata ctttaaaccc 5521 tctaagtttt taatttattt cttgtatttt aacctatcat aaatttcact atattttctg 5581 gccatagtta ttgtattgta ttcctttttc acatcatcta tagcatgttc tataagctct 5641 tttttctttt ctttactaac gttgattgca tttatatagt cttcaatgga atcacatata 5701 aaaccattta cattattttt aataacatca ttatttccta tcgtgtcact aacaatacac 5761 aatttaccca tatacattgc ttctaacaat gccattggca agccttccca acgagaagtc 5821 aatataaata tatccgcttc attcaatttt ctcaatgctg catttctgtc taaccatccc 5881 gtgattctta cattaggaga cgttatttct tcttttaatt ctccattacc tatccatata 5941 aactcttttt ccggcatatt ctcagctatc ctattaaata aagctggatt tttttgatat 6001 gatattcgtc ccaaggtagc aactttaact ttattactat tactcttctt ataatcacct 6061 acaacattag taatttcttt catatttatc ccattattaa catgttctgt atatttagca 6121 attttctggg attctttatc ttctccagga ctacacgata taattacagc atttcccatc 6181 cctaatattt tttcaatatt tctataaacc aatcttttaa ctttactcgt atcagacatt 6241 aaaaaactgt aaccatgtgg tgtataaaat accgtatatt tattattaaa aaaagaaaaa 6301 gccaacctac ccaatacacc cgcctttgat gaatgcaaat gtattatatc tggattcact 6361 tttttcacta ttttttttat ttctatgtat gcttttaaat cttgcaatat atttatagat 6421 cttacaaaat tttctacttt tattagtttt acattgacat taaaactttt tttgaaatct 6481 ttaggtgttt ctttccttac agaataggct acataaacat catacttttt gactagttca 6541 ttagttaaat tagttatata cgtaaatata cctccaccca tagcttcaac aataaaaagt 6601 aatttttctc ttttcataat tctgttcaac ctcttactga tctaatactt aaaactaact 6661 atcagaagat atgtttttat ctaacccact cttatccctt attctatatt ttccttttat 6721 ttctatgacg ttcataatat ttagtgttta catcatattg tttcatcaat tagtttatat 6781 aattttaaat aacaaactaa tttaacccca attaaataat acatggtaaa cttactcgtt 6841 ttccatttta ttacataaca atgtaatcag caatgataga taataaaaca caacattttt 6901 gaaatatatg taagaataaa aatttctgct tcgattatat tttcatgatt attttttatt 6961 aactttttct gattttccat ctagacacag gaccaatttt ttaatttctg caaatttagc 7021 gcttacttgc ataaattttt atatttcttc tatatctaaa tatgccaata actaaaataa 7081 gcctattatt actttaagtt tgtaataata gacttcattt taattactta cattctataa 7141 tttaacattt ctatttttca gctcctaaat taataacatt ttcctctcca aatttttctt 7201 taatccattt taaaatttga gggttaggat tacttttaag ataaaatact actaaatttt 7261 tttggttctt tgtcaaaaag gactgatgcc aaaattttaa ttattatttt caaactatta 7321 gatgaaagtc taatagtttt tttttgtttt aagtagagaa gaaaattaca ttattcttta 7381 gcgaaagcag aatcctgagt ctaaaatgct taaaattatt atagccatag gctatacgct 7441 taattacttt aatgtgatta ttgatacctt caataggacc gttggtaagt ctaggtaaaa 7501 caaaactatt ttctatttct gccttatgtt tcttgatagt ttttaaagct tgtctcattt 7561 ctggtggaag attccaggaa gatgtatcaa ttaataaatt tagtgattga caactatttt 7621 tacggtacat ttgtagaagt aactgataat attcataggc tgtcttcaat tcagaagaca 7681 tatcagataa acgatctaaa acttcagaat cgcttaattc agcatattta aaatttatcc 7741 ttggataata tctatgataa tcaacattat cttgattttt tagaagtagt ttccaaaaac 7801 gtttcaaagc tcgatactca tgggttccag ctccatattc tttcataacc ctagttctaa 7861 ttttattcat agctgtatat gcctgtgcaa ctacatgaaa tttatctgca ataataaatg 7921 cattagggaa taacttctta atcaaactgc ggtaaggtgc atataagtca acagttatag 7981 tcattactga taatctagct ttgtaactat attgaatgaa ataattccta aggaatttat 8041 tatttctttc tggaattata tctataattc gatggttgac tgcgttgatt aaacacatac 8101 tcataccact agatgaaaat cttttaccag atttgaagtc atctaaggat aagtgactag 8161 gaagccagtt acgattgact ttaaaattat tttctacact ctctaaagat ctaataattg 8221 tgtttgaaga tgtaaaagag tccgcagcaa tttcacacat aggtctggat agacttaaat 8281 cacgtacaag tttggcttta acagcattag aaaaatgatc atgatagtta gtatctttaa 8341 atttagctgt cgcagtcttc ttgcattcag gacacagata cttctgtttt cttatagaaa 8401 gcacaagctt tttaccagca gaagaaagat gaacattatt agctacttta gtgccgttat 8461 gtaacatcaa tgccttacaa ttagggcaat acataggata agacaaatac agatgacaga 8521 gcaaagtctt actattttta ataatttttt cttcaatata cgaagtatat tgatatttag 8581 ggtcaatagt taaattaggg tctgtaattc caagtaaaag tttgatatta ttatccatag 8641 agatggtgtc ctttctttaa ttagattggc gtgtgggcca tctcttttat tttgccgcaa 8701 aaatggagaa aataaaagaa ggacagtaat aaaaaaattt tacattatca gtcctaaata 8761 ttatacaacc aatttttttg agctctggta caacacacat agaaaagttt taatgctctt 8821 ttcgatggct cttccccatc ttctaacatc attccatcaa agctatactt ttgccaacta 8881 gactccaaca tcacaaacac attatcatat tcactacctt tcacactatg ttgcgttgca 8941 tatggggttt tcttttccaa atattcaatt gattttttat attctttaaa tggtatttct 9001 tttattcttt cccataaata ctgtccttcc tcttttataa acttatcaaa attatctcct 9061 gtctttatct ccagttcctc ttttgcaagt tcaacaacac ttcctataca gatgttatca 9121 tcgttaactc catccaataa ttttctcata ctctcactta ttttgttttt atccgaaatg 9181 ctaccaattt tcattttact tttcgttaag aattcgccta ttttgccatc ttcatataga 9241 gtaataattt catatattct atctaaatat tttagaattt catctctatt agggttggaa 9301 ttagaaagat tcccatcaaa agataataat gaatctctat taattttttg attaattaac 9361 tctttaaaat tcttatgctc aaatctttta tatgattcct ttttaaattt ccaactatct 9421 ctttttttac aataaatttt aacaacttcc ttaagagttt tatcctctac attttcattt 9481 ttttccttaa catcttttat taagttgata accatatcga tattatataa ctcatataaa 9541 tttggaaatc ctactgcact agctatactc tttttagtta attgtaatct tttaaaatcg 9601 tcatcactta attttaactc ctgataacgt ggatgctgct ttaacaactc ttctgactta 9661 ccataaaaaa ataatgcttt tccttctatg ttatttgttt ttccagattc ttgttgcatc 9721 ttatctatcc taagattatt tccgactttt attacagcat ttggattacg ccaattcttt 9781 ttcttttcta ttctatctag attataatca tttaaatcac ctatacctct gtcataaatc 9841 gcttgcatag aatctccaaa aaaacctatt actacttttt cattatttaa attttttaga 9901 aacatttcaa caacattttt atctgtatct tgatactcat ctataaaaat ataactgtat 9961 ataccttcta caattttact taatttaggt tttgtatcaa ataatttttt tgcaatgctt 10021 aatacttcat tatgtgaaat tactccccga ttccaactta cataatcatc ataagttatt 10081 ttttctaatt ttcttgcatc aaaattttca ggaatattct tattaattaa ttcttctttg 10141 ataagttcat ttaatgccca ttttatctca tcttgaaatt gcttaattaa attccagaga 10201 aatttatgga ttgtactaac aactatattt tttacattta ccctgtttat aatctcattg 10261 actgcattat tcgtataagt tatacataaa attctgcgat ctggatatct ctgaccaatt 10321 tctcctataa cttcacttaa tgaccttgtt ttcccacttc cagctccacc ttccatgata 10381 aaatttgttt tactccttat acattcaata gctctttgaa cttctggctc tattttcgta 10441 tccattctaa tccctcctct atatatttag ggatttgcca tctattatta ccatacatga 10501 gtatccctat tgcaaaattt gtttttgaat cgatacaatt actagataat tcgtatggcg 10561 taaattttgt ttcctttaat tttttaacca atttcaatcc agcatttcta ccatgttcat 10621 ctgctaattt ctgtacaaat tccaaattta agtgtataaa cgaatcttca aagcttgttg 10681 cttggtaact ttcttcctta ctattttttt ctttaatctg atatgcaatt ctcaaatttc 10741 cattaggatc ttctttatac tccacatttt ctttacctct atcttctgtt ttcacttcta 10801 tactaagtat tttcttatct ttccctaaat ttctgaggtc cttaaaactc ttacctttaa 10861 aaaatttttt caaagaacca ttagtagtta ttttcccttc tgctggattt tttattttcc 10921 caccttttat tcctttagca tctatatcag ttataactaa agtttttaaa ttaaggaaac 10981 ttattaattt cgataataca tgggcatgat ttcctattac taaaaccgaa atattttgtg 11041 ataataacgg tggtacatct tttccattat ttttattatt gtctactctc tccatcatag 11101 tgggcaataa tattctttct gtatctcctt ctattaaaat taacttatca gcaaaaaata 11161 tttctgctct acttagagtt atatattttt ttacaaattc aaatacttct ttttcattct 11221 tatataaatt ttcaaggtct gcatatgact ttatttgagc attgtccttt tctttaataa 11281 agaaattagt atcttcaaat ttacattgcg atactatatg agaggaatgt gttgtaatta 11341 tagtttgaac atttaaatta tctttttcat tctctattag tttcccaata ttttttataa 11401 aaacatattg gagctgagga tgagtatgtg cttccggctc ttctatatat aaaatattaa 11461 tttttgatct attactatct tgtctaaact tttgaaaaca tgcttttact tcgaaaataa 11521 tacctaataa attcatatat cccaatccat tataattttc tggcaaatct tctttatcat 11581 attgataact aaatacagta ttccctttta atagcttgct cacatccatt ttggaatgga 11641 tatttacatc ctcttcacca ttaggaaaat taccaaagtt tctaaagtcg tctattacgt 11701 ctttaaaaag tttattatat tccttattta aaattccatc tgttttacta acttcttccc 11761 ttaagctacg tatcttatcc tcctcgtcag aaaaattttc ataatatttt gcagcaattt 11821 gggataatgt acggtctttt tcattgttag aagtatctct tttagcagaa attccagtaa 11881 tatttattat cttctttact atgctactgt ctaatttttc aatagcatct gttaactcat 11941 gactttcata atcatatcct cgtgcataaa cattagtctc aaagtattta tttagatttt 12001 cttgcataaa atcactaaat ttacgatact ctttcaattc tgtatcattg actagatttc 12061 gtaactcttc aattttatga ataattggtt gacacttaaa ctctaacaca actatattgt 12121 tttccatgtt taagtccaac atcaatggta gtatattatt caagtcgtca ttatcatcat 12181 actccatata taaatccaat ataattcctt caatatcttc ttcgttcccc tcttctttag 12241 atactaaaat attatgtatt tctcttctat attgaatatt aaaatcatcc catgataatt 12301 tcctgtcttc agctatcatt ttcttcataa tcttaaggaa tgaagtcttc ccactattat 12361 ttttaccaat tattaatgac aaattagggg ttcccttttc cttatctagt actaatttta 12421 catcttttag acttctatag tttttcactt taacttcatt taaatacata agctcctcct 12481 tttgaacatt tcatttaaaa attatgcatt cgttttcatt ggacgcaatt ttattttata 12541 cactaatcac tacgatttaa ttactaatat gttacattag tattacagaa tataaaaaag 12601 gccaaaaaca atttcatttt tgacctttaa tataaattat caataattaa aatatggata 12661 gattaatcat catatctacg ttcccaatct ggactggaac ctgtcttacc aatggatttt 12721 actttatatt ctccatcttc tttttcaatt tgagcaccgt tatatgtgaa ttgttgtact 12781 ttacgctgat catcattttc aaaactatat ttcacagaat atgatacttc agctttatta 12841 tttcctaggg gagttatact atttatcttt actacatcaa catcttctag atgatcttca 12901 atagtcttga aaaagtcgac caattcatta taagaatcgt tgttctcacc atctatgaaa 12961 tgatctgcag ttgaactgct agccccatat cttaatcctg agaatactga tgataataat 13021 gattcagctt catctttact tactaatcct ttatatcctg gagttattgt gtgaactcct 13081 tggttaatct tatcttcaac agatacttgt ttagatttga tttcttttcc atttacatca 13141 gtagttagat acaacttgag accattagta attggatagt tagtgaattt tttctctcca 13201 tcactatcaa gctttcctac ctttttatca ttaatgtaga tattactatc tttcatacct 13261 ttaacagtga aagtagctgt acttaggtta agttcaacgt tattatcttt accactcttt 13321 acatagaaat ctttctttga actcaacttt tctccattaa cagttccttg agctttaaat 13381 gtatattttc ctggatatat aggtcctacc ttaactgtac gtgaatcatc tttagtagtt 13441 gctattttat taccatcttg atagattttt acattcttat tatttgtaga cacgtaagca 13501 tatcctggat cagcttgtaa tttataagca ggaaagacaa atagtcttct gcctgactgt 13561 acccaactat aattaccata actaccatta gacattaagc tttgtttcat gtagtatatg 13621 ctactttgac tacctgaaaa ttgcttttta aaagctttcg cctcttcttt aggaactttc 13681 tttgaacctt cagttgtagt tagatagcca gatacatcgc tatcgctttt tgataatgca 13741 gttgtaaatc tattcaactg gttctgtgat gaataatatt tatttcctgc aatatatgct 13801 ccaattaggg caacaagtac tacaacaggt atcataactt ttttattgat aggtttcttt 13861 ggcctattat agttgttgtt atttggtcgg ctaaattgtc cagtactttg gcttacttcg 13921 gtaggatttg aagattcaag gcttttattt tcttcaacct tctctacatc ctctgacaac 13981 tgatagccac agttagcaca aaacttttca ccagcatcaa ctttttgacc acaatttggg 14041 caaaatctgt tttcactcat cgctatctcc cccatttcaa ataactatat agctcctatt 14101 aattcactaa ttacatcagt taacataccc gcataatggt taactacaat ccatcctgca 14161 atacttatta taattatatg ggcaatgtaa attaccaagc ctacataaat attatccatt 14221 tttgtttctt tcaattcaaa tgctactgat aatattccta ttacccatat cattgacatt 14281 agtcctaaaa caacatcaat taatacaacg gagttcacac ttgcattaga tacaataaat 14341 gaatatacaa atagcactgc atttaataac actaatgaag aagtcttatg tgcaacttca 14401 ttcactaaat ctaaatactc tttattacta tctgaaaatc ctttttctat taataatacc 14461 gctccaatta ttgcaagtgc agctataaac actgctaaaa agaatactac aaatacatta 14521 aaacctactg gattacttgt gctagaagaa cttccaccag aaaagaatga cattattgaa 14581 tttgaacttt caacaaaagc acctgctatt tttcttacta aaatcattac tgataatgca 14641 aacataacac cttcaattgc taaagttact aagccagtat atttttcgcc agcttgaact 14701 ttaaatggat gtttccatga agtaactaac caatcccaat agctcataga tacttctttc 14761 attctgtctg tgtctacagt ttgtctagct ctgttaacat tagtggtatt ggtagtatta 14821 accgtattat tgacatttcc ctgtactaac tgatatccac aagatgtaca aaattttgca 14881 ccttctttta tgtctgaacc acaatttgga cacttgttca tagtaaattc cccctaataa 14941 aaatatgtct acattatact actatgtttc ttaaaattta attatttcat aatatttaat 15001 ttggctttta atctcaatat tctttttact gaattatcaa tttgtttttg ggatatatct 15061 ccacgcttta ttgcatcttt gatggctggt attccatcta cataaccatt gcttagtaac 15121 atatcatttc cagcttcaat cgccatcaca tctatatttg tgtgctgctt ctgcgcaaag 15181 ctagttaatg ctcccattcc catatcatca gtaataataa cacctttaaa tttcaattct 15241 tttcttaaaa tttcatgtac tggttttgat acagaagctg gtttagttgc atctaaatta 15301 ttaacaacaa catgtcccac caatactgaa tcagctttag cttttattcc agctttaaat 15361 ggtagaaaat cattttgcct aaattcattt atactacgtc catcgctagc aaaacctgta 15421 tgtgtatctc cagctgaacc ataccctgga aaatgcttta ctgtcgcagc tacttgttgc 15481 ttttgaattg ctggtacgac ctttgacaca tattgtgctg ttaattgata attctgaccc 15541 agtgtcctat catatataaa gctgtttgga tcattagaaa catctgcaac tggtgcaaag 15601 tcccaattaa tacccaaatt acgtaaaatt tcagctacac tactgtattc tttcactact 15661 ccagacattc cagattgttt atatacttct tgtggggaag gaaattttct tccatttgtt 15721 aattgtggac ttgtacttaa tctagaaaca attccacctt cttggtcagt agagataaac 15781 aacccatact tactagcatt ttgaaaattt gcatcttttt gtttcattgt atctgcattt 15841 tggttgctga aatcttctcc aaataaaaca attcccccta aattatattt ctttatatca 15901 tttgtcattt tagcagcatc gcctgaacta ggactcatat ataattgccc tatcttctca 15961 tctaatgtca tattatttac gattttctga atttttttat cagaaatatt cttagcgaat 16021 accttgtctt gaaaagctac tatacacgat aagcatataa taactaccag taaaaacttt 16081 ctcatacatt ttctccctct aactatatta ataactcaag tttatagtaa cataagatta 16141 tatgtctata aataaaaagg ttgttcacta tgtgaatttt gttattaaaa tattacacaa 16201 cgtgtccacg atatgatatc tagacagcaa ataactaaaa taagcccatt attactctat 16261 aactgcaata ataggctcta acaaaattat ttacttgtta attttactta acttcactta 16321 aaaactcatc caacgcttct ttccaatctg gaaatacaaa tcctgtttcc ttagctaact 16381 tcattacact gtagtgtggt ctgaatgcag ctgttggata ttgatctgaa gttacaggtt 16441 gtacatcaac atctgtatct ttcaatattt ctttcgcaaa ttcataccat gaacattggc 16501 catcattaca acaatgatat acaccatatt caatcttatt atctactaaa tatgtcaaga 16561 attctgctaa tgttctagtc catgtagggc gtcctatctg atcatcaaca actgtcaact 16621 tatcatgatt ctttgctaga tttaacatag tgtatacgaa gttatgtccc cattgcccat 16681 atacccaagc tgttctaatt atgtaatact tatcgcaata tttttgtact gcttcttcgc 16741 cggcaagttt tgctttacca tattcattgc gtggaccttt aggatcatct ggtaaatact 16801 caccacttgt acgattacca tcaaaaacat aatcagtact tacatagagt aatgttgccc 16861 caactttttg acatgcttta gcaatatttt ctgtcccatc aacgttgact ttccagttaa 16921 gttctttacc ttctccttca gccttatcca ctgctgtata agctgcacaa tgataaacta 16981 cttcgggttt attcttttca aagtaagcat ccactgcttt cttatctgtt atatctaatc 17041 cttgtgaatc ttctgctaga tattcttgtc cacgttcatc taacagatgt tgcatttctt 17101 gacctaattg tccatttgca ccagtaatta aaattttcat ctaatatctt ccttccaatg 17161 ataaagtaaa accccaggaa aacctgggga aatttttatt gcccattttt agcgtattta 17221 gcttcaactg cagccttttg atcttgccac cattcacgat ggttagtata ccaatcaatt 17281 gttgctttta ggccttcttc aaagttagta tattgaggtt cccaacctaa ttcgttgcgt 17341 aatttacttg catcaatagc atagcgtaaa tcatgtcctg gacggtcttt aacttgatcg 17401 taagcatctg ctggttgtcc cattaatttc aagattaatt ctagaacttc tttattgttc 17461 ttttcaccat cagcaccgat taagtatgtt tcgccaatct taccttcatt caaaatcttc 17521 caaactgcac ttgaatgatc gttagtatgg atccagtcac gtacattctt acctgttcca 17581 tataattttg gacgaatacc acttaaaata tttgttatct gacgtggaat gaatttttca 17641 atatgttggt aaggaccata gttatttgag caattggaaa tagttgcttt taatccaaat 17701 gaacgcaccc atgctctaac taacaaatct gaacttgcct ttgaagatga gtaaggacta 17761 cttggtttat atggagattc aggtgtgaat ttttcacctc gaccttcacc atgtcctggt 17821 aaatcttcac gtaatggcaa gtcaccataa acttcatcag tagaaacatg atggaaacgt 17881 acatcatact tagtacatgc ttcaattaga actgatgtcc caacaatatt agtttggata 17941 aaaggatcag gatttctaag tgagttatca ttatgacttt cagcagcata atgtaccacc 18001 gcatcagcat tttgaactaa cttatctact aattccttat cacaaatatc cccgacaact 18061 aactctacac gatcttgtgg taagccagca agattttctt tatttccagc atatgttagt 18121 ttatccaata ctgtcacatg aacttcagga tgattattga ctacataatg tacaaagttt 18181 gaaccgatga atccagctcc accagttaca atgatattct taaacatcaa gatacctcct 18241 aaatttcgcc atagacaaat ggattgcctt tttcaaattc tgttaaagta ggttggttag 18301 catctttttc agatgtgatt gccttatcta aatcgattgg ccaatcaata ttaagttcag 18361 gagtcttgaa ggagatacca ccatcagctt ctgcatcata gtaattatca catttgtaaa 18421 ggaagttaac gttgtctgtc aaagtaacaa atccatgagc atagccctta ggtactaaca 18481 attgacgatg attactttca gataagatgt atccttccca ttgcttatat gtaggagatc 18541 ccttacgtaa atcaacgatt acatctaaaa ctgccccagt tgctactcga atcaactttg 18601 tttgtgcagc tttaccacgt tgaaaatgca agccacgtaa aacacctgct tgagtagaaa 18661 gagagtgatt atcttgaata aaatcaaaat caattccagc tgctttgaaa tcacgatctg 18721 aataactttc tgtgaaaaaa ccacggttat ctccaaatac tgctggtgta attaatttaa 18781 catcttgtaa ttttgtttct tttacaatta attttcccat //