LOCUS NC_007355:12 18214 bp DNA linear BCT 04-OCT-2011 DEFINITION Methanosarcina barkeri str. fusaro chromosome 1, complete sequence. ACCESSION NC_007355 SOURCE Methanosarcina barkeri str. fusaro chromosome 1, complete sequence. COMMENT locus start: 3153386; locus end: 3171599 FEATURES Location/Qualifiers source 1..18214 /organism="Methanosarcina barkeri str. fusaro chromosome 1, complete sequence." gene 0..1760 /gene="" /locus_tag="" /db_xref="3153386..3155146" CDS 0..1760 /gene="" /product="hypothetical protein" /translation="MLFSKLRLTKKQFGIIGTLILAILLVVVELIPAVSAEEEENYSV TAEKAFEHANAHIIDFMSSGAPGFENWTGASIDPEPLELYDINGQKLFYEFSTYKHNI LVGKIYVGANKTLGPSVQVIETTTNLYNTTEALKKSIEVARNEYPDGEIKSTKMVEYS YPRIGAMTVVKDKTSGDEHRIFVDVYSLEVVPDRPVTETQLGVWSMYEHKVKNRVGGN LIEWNKSDKYTKSIEKEVANKGICISVPVILDNYSNYETSNVYYGYYHYFFGLDSYGN TVIARYGKLPVLKSDEQKENWNSTLGELGNNIKDTVASKYMYPHGEVVTCGTNSKGYF VILFKYGNVSESLINDIYSLIDNSAKQMDIQDIPVEFGYGIYREEIPLDSEQGIYHWF GDSTANLSESDIHVLEEYMKEKPTIPMDKTVVAYGKIPLLKDQNEIMTWADKLSAISG STQDKITPYMEKGQVIVYGAELTRLDVGINETLPSEEKNAIVKEIYQIIDEEARKQNV TTVPVIFDEGIFIDELVTEDVKIPLEENNEELSNSNNSNSKSDNGSKPSESSEIRSTP GFGLLGSLICLYGGWKFRKK" gene 1953..2576 /gene="" /locus_tag="" /db_xref="3155339..3155962" CDS 1953..2576 /gene="" /product="hypothetical protein" /translation="MTKKPIYKILLIVVFIIFLIFIIPMILFTSTNTDSKMSIDTKTP VNELKAAGLFIKFEDGVSESEVKTILESYNLTMNYSIKYNTHYVEGKYYIILDKDNWD IRREISKKMREEKKDWIISSPAHVIRKGDDYVFMVSEQAVQDENFLAILNKYNIQVNK FVECLVRFEKPEGSRYWIPERNAIQIKNELEMNENIFSVYIDHIYDQ" gene 2842..3441 /gene="" /locus_tag="" /db_xref="3156228..3156827" CDS 2842..3441 /gene="" /product="50S ribosomal protein L15" /translation="VFKLVKSYYTYVRDAWKNPDETYVNELRWERMQVWRKQGSVTRI ERPTRIDKARSLGYKAKQGIVVARVKVRRGGLGKTRPNRGRRTQKMGTSKITGGMRIQ RIAEARADRKYPNLEVLNSYWVGEDGKNKWFEVILVDPFHPVIKSDKNLKWVCDPSVR DRAARGKTSAGQKGRGMSARGKGTEKTRPSIRANKSRGK" gene 3438..3881 /gene="" /locus_tag="" /db_xref="3156824..3157267" CDS 3438..3881 /gene="" /product="hypothetical protein" /translation="VIHHIILRVIAHATEDVTRVREALDFFLSGAGVREDGKLIEELQ AEGHHGNPITILSVQLKRKADCLNFARFIREGFSEEDVAKLREEMPERLDDDQVFHLR FDKQAAYLQQVRLTDSSDAIIAKVKIETYPKNREKAGAIVEELFG" gene 3874..4593 /gene="" /locus_tag="" /db_xref="3157260..3157979" CDS 3874..4593 /gene="" /product="ribonuclease P protein component 3" /translation="LGKPKFYDFCVHAVPDGENTVDQLSALARHLGYSGIALTNHSDK LPQSQPVLPSTNEFEVFKGIELVEENPSKLHGLIGKFRKSVDVLIVHGGSENVNRAAL ENPRVDILNHPAFAKSSGLNQVLAKSAAENDVAISLIIRPLLHSRGPRRVRLLSNLRA NLDLARKYDVSLVLSSGAMSCFDLRSPMETLALAEVCGLEEDEALEAITVVPERIISR NRPGPGHVREGIEVLEEGDYS" gene 4590..4997 /gene="" /locus_tag="" /db_xref="3157976..3158383" CDS 4590..4997 /gene="" /product="putative ribonuclease P subunit P14" /translation="LKRLLPSLRAKKRYLAFELISEVPVSRSDLVKEVMFSASSLLGD VTASECDIKVLGFEESKGIIQCAHTKVKETRASMATLTRINGKRATVHILGTSGTIKR ATEKFLQNTAFEPEIRINPKRLKNNNLSRVQES" gene 6060..6809 /gene="" /locus_tag="" /db_xref="3159446..3160195" CDS 6060..6809 /gene="" /product="proteasome subunit alpha" /translation="MQMAPQMGYDRAITVFSPDGRLFQVEYAREAVKRGTTAVGIKAA DGVVLLVDKRITSRLVEAESIEKIFQIDDHIGAATSGLVADARSLVDRARVEAQVNRV SYDEPIGVEVISKKICDHKQTYTQYGGVRPYGTALLIAGVDDNLPRLFETDPSGALLE YKATAIGAGRNAVVEVFEAEYRQDMNMDAAILLGMDALYRAAEGKFDASTLEVGIVSL QDKKFRKLVPEEVENYVQQILEKHKETENKE" gene 6888..7580 /gene="" /locus_tag="" /db_xref="3160274..3160966" CDS 6888..7580 /gene="" /product="hypothetical protein" /translation="MVSLDEAVTARLKRGSKHFEVLVEPEGALAYKRGEDVNLEDILA VETIFEDANRGDRAAESDILNSFETTDPFKIAAVILKSGELQLTAEQRKRMLEEKKKK VIYTISRNAINPQTKAPHPPARIEKAMEEAKVHIDPLKSVDQLVNITMKAIRPLIPIR FEEVNIAVKIPPEYAPKAYGDISKIGSITKEEWQRDGSWIAVVRIPAGVQTDLYALIN HLTKGEAQTKLL" gene 7592..8374 /gene="" /locus_tag="" /db_xref="3160978..3161760" CDS 7592..8374 /gene="" /product="exosome complex RNA-binding protein 1" /translation="MDKKIVIPGDLISENSKKAGYGTYVKNDKIYSLFCGIENLKEDK VGVIPLAGVYIPSANDVVIGIVIVVTPSNWIMDIASPYDGLFHVSEYPRRIESREMHE VLNVGDSIILRVKDVDNSMKVELALRDSSFHKLKTGQIVEVEPVKVPRVIGHGGSMIS MLKKETNCSIFVGQNGRIWIDGKDDDVELLSKALRKIEAEAQRSGLTDRIYNFLKNER SKQKESKPAKFFKSGKKEVKLPKEDHSEEIYRKIDVLLDPNN" gene 8448..9953 /gene="" /locus_tag="" /db_xref="3161834..3163339" CDS 8448..9953 /gene="" /product="exosome complex exonuclease 1" /translation="MSDKPEKLITDDGLRLDGRHADEIRPMKIEIGVLSRADGSCYLE WGRNKVLVGVFGPREAHPRRSQRADTAVIRYKYNMASFSTEDRARPGPSRRSIEISKV SREAFEPVIMAELFPKTAIDIFVEILQADAGTRTAAINASSIALADAGIPMKGLVTSC AFGKVDGQIVLDLNKEEDNYGEADFPVAMTQDGEITLLQMDGNLTTDEIRKGFELVKK GCKEILEIQQAVLRTKFETPVEEPEAKAAEEVEETELEVVETESSLEYAPEAAVVEEI IEEAEEPEEGISEETVEACAVNKEAPECEELEKVIKDAEAEVVEGEVTEKVVEAEVEE EAEEEAFEDKADFESSFEASFEEVSEAEELEEPESEEVVSGEEAEVESEIEESADEEA QPEVETQLEVETQLEEKAEVEEETQLEEKVQPEEEAGIEEVQPEEEAGIEEVASEETF ESEPEIESEAESKKEAPAEQTIEESEEEKCKGPWKVVKDPSESGSRGENDE" gene 9946..10728 /gene="" /locus_tag="" /db_xref="3163332..3164114" CDS 9946..10728 /gene="" /product="exosome complex exonuclease 2" /translation="MSEVIATLKKDYIYNLMIKGKRQDGRGFKDFRDIKLETNVIPKA EGSAKVTLGDTQVLVGVKLQPGTPFPDSQDEGVIITNLELNPIASPEFEPGPPREEAI EMARVVDRGIRESGAIDIKKLCISVGESVWIAYIDVHVLNDDGNIIDASSLAAIAALM TTIVPNEQHGIGADVPLAMKEMPVGVTLAKIGSKLMVDPSLDEGAVCETKLTVVSSSD GSVAGMQKMGTVPFTEAEVLEAIDMACEKAAEIRKLYLEALV" gene 10911..11195 /gene="" /locus_tag="" /db_xref="3164297..3164581" CDS 10911..11195 /gene="" /product="50S ribosomal protein L37" /translation="MAKKFTKKGRISRSAGRFGARYGRKDRKLVADLEERMRAPHVCT KCARPTVKRIGTGIWKCSKCGHTFAGGTYIPYTSVGQTLLRTMKNVAEAK" gene 11216..11353 /gene="" /locus_tag="" /db_xref="3164602..3164739" CDS 11216..11353 /gene="" /product="DNA-directed RNA polymerase subunit P" /translation="MGYKCTRCKQKVEIDYEYTGIRCPYCGHRILVKERPTTIKRIKA E" gene complement(11895..12368) /gene="" /locus_tag="" /db_xref="3165281..3165754" CDS complement(11895..12368) /gene="" /product="transcriptional regulator" /translation="MVKERILIVEDEQIVAMGIRMMLKNLGCTVTGIASSGEEAISKA ESTRPDLVLMDIMLKGTLNGIEASKEIISRFGIPVVYLTACSDRKLLEQIWNMGFGCI LKPFDEKDLEKSINIVLSRCELENADVKKNSRKLQNDSEKFNSASGYLPGLEGSK" gene 13249..14439 /gene="" /locus_tag="" /db_xref="3166635..3167825" CDS 13249..14439 /gene="" /product="transposase" /translation="MRKMAIYCCKCSNNQSLSHFISTSPWRPADLLKSVRTYAIKTIG KNGVLILDESSIKKSGNSSVGVSHQYCGNLGKKNNCQVGVFLAYFKKQKRMLIDERLY LPQKWINDKARCLKAKIPPEKIKFRTKHELGLEMIDNAIEEGIPFSYVTMDGFYGENP ELLTELENRGLTFVADVAVDTLVYIEEPLVGIPEKKGTRGRKPTISKVLNTLSTRIDS LSSSIDGWKLIKVRKTERGYKKVYFKAIKVWRRQNKLPCEKPLWLLISKDVESNDIKY SLCNASEDTSLDELAKMQSSRYWIERAFQDAKVYCGMSEYMVRSWNAWHHHMALVMLA MLILLSYKIKFMKFHKISLHGVILIMKFHNPLKILNAGELARILNHDNEMRDRARASR LKGS" gene complement(15145..15855) /gene="" /locus_tag="" /db_xref="3168531..3169241" CDS complement(15145..15855) /gene="" /product="3-oxoacyl-(acyl-carrier protein) reductase" /translation="MSLAGQTALVTGGSKGIGRAICLALAKEGANIVIAARNESEIKE MVNKLKAMGSKAMAVQADVQNEEDVRRLISMTIDKCGRLDILVNNAGVAYKKKLEDTT LEEYNQTMDTNLKGVFLCTKYAIPYIRESNNGKIINISSVGGLHGLPDFSAYCASKFG VNGITESVAAELEGEIKVYAICPGAVDTDMYRSLFSDRPSLKPEHIAEKVLELASPDS KVTSGKIIEIQALPVPQL" gene 16953..18035 /gene="" /locus_tag="" /db_xref="3170339..3171421" CDS 16953..18035 /gene="" /product="hypothetical protein" /translation="MYFLRLITMDLSQINTKLIIILLLIFVASIFYTFNAKYSGIYPE KSLDNISNNSINADLHSGEPVKNNLDNIDNDPIDAKIYPGDSVQNAINTVSSGGTVIV YPGLYKENLVVDKPLKVISSNEGGSAYASIQAADPEKDVFHITADNVTISGFNITGSQ DKAGIYYSGSGGNITRNKLSYNNYGVYFNDSKVNILENNEVNNNSLGIYLRNSNNNQL KSNNITGVGIFVGLDNNATGIYLEDSDNNKLMSNTIAKLWDGVNFTESSNNELNNNSI LHNYFSLSLINSNNNKVLNNTIVRRGYSFSVVLANSQNNTLQGNNKNLNTDFKIYYSF KSTNNTLEGELYTSNEQGTGGVFRVI" ORIGIN 1 atgttattca gtaaactacg attaactaag aaacagtttg gaataatagg aacactaatt 61 ttagcaatac tgctggttgt tgtggagtta ataccagctg ttagcgcaga ggaagaggag 121 aattattctg taactgcgga gaaagccttt gaacacgcaa atgcgcacat aatagatttt 181 atgtcatccg gcgcccccgg ttttgaaaac tggacagggg cgtctattga tcctgaaccg 241 cttgaacttt atgatataaa cggtcaaaaa ttattttatg aattttcaac atataaacat 301 aatatattag taggtaaaat ttacgttggt gcaaataaaa cactggggcc atcagtccag 361 gtcatcgaaa ctactacaaa cctgtacaat acaactgaag ccttgaaaaa atcaattgaa 421 gttgccagaa acgaatatcc ggatggggaa ataaaatcaa ctaagatggt tgaatatagc 481 tatccccgta ttggggcaat gaccgtagta aaagacaaga cttcaggaga tgaacatcga 541 atatttgtag atgtatacag tcttgaggtg gtaccggata gacctgtaac tgaaacacaa 601 cttggcgtct ggtcaatgta cgaacacaaa gtgaagaata gagtaggcgg aaatttaata 661 gagtggaata aaagtgataa atatactaaa tctatagaaa aagaggtagc taataaggga 721 atttgcatca gtgtgccagt tatactggat aattattcaa attatgaaac cagcaatgta 781 tactatggct attatcacta cttttttggt cttgattcat atgggaatac tgtaattgcc 841 aggtatggaa aacttcctgt actaaaatct gatgaacaaa aagaaaattg gaactctact 901 cttggagagc ttggcaataa tataaaagat acagttgcct ccaaatacat gtatcctcat 961 ggagaagtcg taacatgtgg aactaattcc aagggatact ttgtgatttt attcaagtat 1021 ggtaacgtaa gtgaatcgct tataaacgat atctactctc taattgataa ttctgcaaag 1081 cagatggata tacaggatat tccggtagaa ttcgggtatg gtatctatag agaagaaatt 1141 ccactggatt cggaacaggg catctatcat tggtttgggg atagtaccgc gaacctgtcc 1201 gaatcagaca tacatgttct tgaagaatat atgaaggaaa aaccaacaat accaatggat 1261 aaaactgttg tagcttatgg aaaaattcct ttattaaaag atcaaaatga aatcatgacc 1321 tgggcagata aactttctgc gatttctggt agcacccagg ataaaatcac tccatatatg 1381 gaaaaaggtc aggtaatagt atacggagcg gagctaacta gactggatgt aggaattaac 1441 gaaacgttgc cttctgaaga aaagaatgcc atagttaagg agatttatca gattattgat 1501 gaagaagcaa gaaaacaaaa tgtgactact gttccagtta tttttgatga gggaatattt 1561 atcgatgaac tcgtgactga agatgtaaag atacctctag aagaaaacaa tgaagaactc 1621 agtaattcaa acaatagcaa ttccaaatct gataatggaa gtaaaccaag tgaatcaagt 1681 gaaattagat ctactccagg ttttggatta ttgggaagct tgatttgttt atatggagga 1741 tggaagttca gaaagaagta atgccaaaat ggggttcatg ttattattta ccattgaaat 1801 ttctattgga ttaattctag aaccttttac taaagcaaaa ggtatgttct ctaaaccgaa 1861 gcaaatgtag atcgagaaaa ttacagtata taagggggct aagactccta atttttttaa 1921 acatggggaa tattacacag gagtttgttt ttcatgacga aaaaaccaat ttataaaata 1981 ttgcttatag ttgttttcat tatttttctg attttcataa tccctatgat attatttaca 2041 tcaacaaaca ctgattcgaa aatgtcaatt gatacgaaaa ctccagttaa tgaactaaag 2101 gcagctggct tatttatcaa atttgaagac ggtgtttccg aatcggaagt taaaactatt 2161 cttgaaagct acaacctaac tatgaactat agcataaagt ataacactca ttatgtagaa 2221 ggcaaatact acataatatt agacaaagac aattgggaca taaggcgtga aataagtaaa 2281 aagatgaggg aagagaaaaa agactggatt atatcttctc ctgctcatgt aatcaggaaa 2341 ggcgatgatt acgtatttat ggtatctgaa caagcggtcc aagatgaaaa ttttcttgcg 2401 atactgaata aatacaatat tcaggtgaat aaatttgtcg agtgcttagt tcgttttgaa 2461 aagccggagg ggtccaggta ttggattcca gagagaaatg caatccaaat aaaaaatgag 2521 cttgaaatga acgaaaatat tttttctgta tacattgacc acatatatga tcagtagttt 2581 atttctacat ctgagaaata gcttgagttc taacggttac ttccctgaat tttctcagaa 2641 acccacagct tttctttttc tctttttaat atatttccca tcttctctct ttttgcgtag 2701 agttttcact taatcgagct gtttatgggc aaagctttaa atcagatggt tcagtttatc 2761 ccatgtttca ttttcgggat tagatcccgt tggaatgtgg tcctgcaggc agggctgaac 2821 cgtgaaacaa aagtgaaact tggtgtttaa attggtaaaa tcttattata catacgtacg 2881 tgatgcatgg aaaaaccctg atgagactta cgtgaacgaa ctccgctggg agcgcatgca 2941 ggtctggaga aagcagggat ccgtgaccag aattgaaaga cccacaagaa tcgacaaagc 3001 acgatctctt ggatacaaag ccaagcaggg cattgtcgtc gccagggtaa aagtacgccg 3061 cggaggactt ggtaaaacaa ggcccaatcg tggaagaaga acccaaaaaa tggggacgag 3121 taagatcaca ggtggcatga gaattcagag aattgccgaa gctcgtgcgg accgcaagta 3181 cccgaacctt gaagtcctga actcctactg ggtaggggag gacggaaaga acaagtggtt 3241 tgaagttatt cttgtagacc ccttccaccc tgtaattaag agcgataaaa accttaaatg 3301 ggtatgcgac ccgtccgtta gggacagagc cgcaaggggc aagaccagtg ccggccagaa 3361 gggcagaggc atgtctgcac gcggaaaagg tactgaaaag accaggccga gtatccgtgc 3421 aaacaagagt cgaggcaagt gattcatcac ataatactgc gtgtgatcgc ccacgcaacc 3481 gaagacgtaa ccagagtccg tgaggctctg gacttttttt tatccggtgc cggcgttcgg 3541 gaagatggca aactgattga agaactccag gctgaagggc accatggaaa tcccattact 3601 attctgagcg tacagcttaa aagaaaggca gactgtctga attttgcacg ctttattcgg 3661 gagggatttt ccgaagaaga cgtagcaaag cttagggaag aaatgcccga gaggctggac 3721 gatgatcagg tctttcatct ccgctttgac aagcaggctg catacctgca gcaggtgagg 3781 ctgactgatt cctcggatgc gattattgca aaagtcaaga tcgagactta tccgaaaaat 3841 agggaaaaag ctggagctat tgtggaggaa ttgtttgggt aaacctaaat tctacgactt 3901 ttgcgttcat gcagtgcctg atggagaaaa tacggttgat caactttctg ctcttgcccg 3961 gcatttaggg tacagcggaa ttgcgcttac aaaccattcg gataaacttc ctcaatcaca 4021 acctgtattg ccctctacta acgaatttga ggttttcaag ggaatcgagc ttgtggagga 4081 aaatccctcg aaacttcacg gactcatcgg aaaattcagg aagtccgtgg atgtcctgat 4141 agttcacgga ggttcagaaa acgtcaacag ggctgctctg gaaaacccga gagtagatat 4201 cctgaaccac ccagcttttg ctaaaagcag tggattaaat caggtgcttg caaaatccgc 4261 agccgaaaac gatgttgcaa tcagcctgat aataaggccc ctccttcatt caagaggtcc 4321 aaggcgcgtt cgtctgctgt ctaatctaag agcaaacctt gaccttgcca gaaagtacga 4381 tgtttccctt gttctttcaa gtggcgcaat gtcctgtttt gatcttcgct ctcccatgga 4441 gactcttgct ctggctgaag tctgcgggct tgaagaagat gaggcccttg aagccattac 4501 tgttgtacct gaaagaataa tctcaaggaa ccgccctggt cccggccatg ttagagaagg 4561 tattgaggtg cttgaggagg gagattactc ttgaaacgcc tgcttccttc gcttcgtgca 4621 aaaaagcgct atctggcctt tgagctgatc tccgaggtgc cagtcagcag gagtgatctg 4681 gtcaaagagg tcatgttttc ggcttcgtcc ttgcttggag atgtcactgc cagtgaatgt 4741 gatatcaaag tgctcggttt tgaagaatct aaaggtatta ttcaatgtgc tcatacgaaa 4801 gtaaaagaaa cgagagcatc catggcaact cttacaagga tcaacggaaa aagggcaact 4861 gtgcatatac ttggaacttc aggcacaatt aaaagagcaa ccgaaaaatt tcttcagaat 4921 acggcctttg agccagaaat caggatcaat ccaaaacgtc tgaagaataa taacctgagc 4981 agggttcagg aaagctaaac tgcaagggtt cagaaaaact gaatctagga ttcgtgaatg 5041 tcaaagccca ggaatttaaa agtttcaaac tttccgggtt cgggaaagtt aattaagcag 5101 tttttctgat aacggctttg cgccagggtt gagaatcctc agctttgagg ttttaaggaa 5161 actattataa taaactatca ggacgctgtc tgatatatac tatgatgaat gagtatatta 5221 atgagtatat tgatgtaaca gataatattc attgggtaac agatttaatg aatatattga 5281 tgtaacagat aatattcatt gggtaacaga tttaatgagt atattgatgt aacagatata 5341 atattcattg gataacagat tcaatgaata tattgatgta acagatataa tattcattgg 5401 caaagctgat tagcagtaaa atagttggtc cagagtaaat tcaaacgatt gcgagcctca 5461 tcggaacgca gattgaaacc tgaattgagt gaaacggtgg aagcaaaaac ccttttatag 5521 agggctcaaa atacggcttt aagcacggga aaatttcggg tctcataagc attataactg 5581 agtaaataca ctttattagc ggacttagtt aacattgaaa ctggacctta atgactatta 5641 aaaacctcct gaagtgcgcg aacccaggtt ctggaaaacg tactttgcag ggtagaagtt 5701 ttgcagggta gaagtgcctt tgaattccct gtaaccggga tatttctcgc aggtttcgtc 5761 ctaaaaagta tctcaggatt ggaagttccg aataaaaggt aaaaaactct aataaggaag 5821 aaatacgtta taggaaatca aaaattggtt tccttacctg aatgctgggt cggggacttt 5881 aagctcctga attttcggga tatcctcgca gcagttcacg atcactgacc aaagcctttt 5941 tggggagggc ggtgatttag ctacgaacct gcggacaaag atcctttaag gaaaaaaaga 6001 ccggtttctt gccgggaaga tgaaaacaat atacaataaa aattaaggga gatacggaat 6061 atgcagatgg caccacagat gggctatgat agggcaatta cggtttttag ccctgatgga 6121 agactttttc aggtagaata tgcccgcgaa gcggtcaaga ggggaacaac agccgtggga 6181 atcaaagcag ctgatggggt agtgctgctt gttgacaagc gaataaccag caggcttgta 6241 gaagccgagt caatcgaaaa gatatttcag attgacgacc acataggggc tgcgacttca 6301 gggcttgtgg cagatgcccg ttcccttgtt gacagagccc gtgtagaagc gcaggtcaac 6361 agagtttctt atgatgaacc cataggtgtg gaggttatct ctaagaaaat ctgcgaccac 6421 aagcaaactt acacccagta tggtggagtt cgcccatatg ggactgcact tctgattgca 6481 ggcgtggatg acaatctgcc aaggctcttt gagactgacc cgagcggtgc tcttctggaa 6541 tacaaggcaa cagctatagg cgcaggcaga aacgcagtcg ttgaggtctt tgaagcagaa 6601 tacagacaag acatgaatat ggatgcggct atccttctag gtatggatgc actctataga 6661 gctgccgaag gcaagttcga tgcgtctacc cttgaggtag gtatcgtgtc acttcaggac 6721 aagaaattca ggaaattagt tcctgaagaa gttgagaatt atgttcagca gatccttgaa 6781 aaacataagg aaactgagaa caaagaataa aatctatata tagttgagat tgagtactca 6841 gagaatcttc ggattctcaa aattatattt tggagaaggt atttgaaaat ggtgtccctg 6901 gacgaggcag tgactgcgcg gcttaagaga ggcagtaaac acttcgaagt cttggtcgag 6961 cccgaaggag ctctggccta taagcgagga gaagacgtaa accttgaaga tattctggcg 7021 gttgaaacta tcttcgaaga cgcaaaccga ggggaccgag cagcagagtc cgatattctc 7081 aattcttttg agacaacgga tcccttcaag attgctgccg tgatcctgaa aagtggggag 7141 cttcagctca ctgctgaaca gagaaagcgc atgcttgagg aaaaaaagaa aaaagttatt 7201 tataccattt ctaggaatgc aataaacccc cagacaaaag cacctcatcc tcccgcaagg 7261 atagaaaagg caatggaaga ggcaaaggtg cacatagacc ccttaaaaag cgtggatcag 7321 ctggtcaata tcacaatgaa agccattcgc ccgcttatac ctatacgctt tgaagaggtc 7381 aatattgctg tgaaaatccc tcccgaatat gctcccaaag catacggaga tatttccaag 7441 ataggaagca ttacgaaaga agaatggcag cgtgacggct cctggattgc agtggtaaga 7501 attccggcag gagtccagac tgatctttac gctcttataa atcatcttac gaagggagag 7561 gctcaaacta aacttttata agaggatgtt ggatggataa aaaaatagtg atccctggtg 7621 acctgatatc cgagaattcg aaaaaagctg gatacgggac ttatgtcaag aacgacaaga 7681 tctattcttt attttgtggc attgaaaatc tcaaagaaga taaagttgga gtgatccctc 7741 ttgcgggagt ttatatccct tccgcaaatg atgtggtgat cgggatcgtt attgtggtta 7801 ctccatccaa ctggataatg gatattgctt ctccttatga cggcctgttc catgtatccg 7861 agtatcccag aagaatagaa tcccgggaga tgcatgaagt tctgaatgta ggcgactcta 7921 taatccttag agtaaaagat gtagataatt ccatgaaagt cgagcttgcc cttagagatt 7981 cgagcttcca taaattgaaa acaggtcaga tcgttgaagt tgagcctgtg aaagtcccac 8041 gtgtgatagg acacggtggt tccatgatct caatgctgaa gaaagaaaca aactgcagca 8101 ttttcgttgg ccagaacggc agaatatgga tcgatggaaa ggacgatgat gtggagcttt 8161 taagtaaggc tctccggaag atcgaagccg aagcccagcg ttccggattg acggacagga 8221 tctacaactt tttgaaaaat gagcggagca agcagaaaga gtcaaagccc gccaagtttt 8281 ttaaaagtgg taagaaagag gtaaagttgc caaaagaaga tcattccgaa gagatttaca 8341 ggaagatcga tgtgttactg gatccaaata actgagttct ggctaggcat gagggatttt 8401 agggaagctt ctgtaaagta tttgttagga gtttttggag attaaagtat gagtgataaa 8461 cctgaaaaat taatcactga cgatgggctg cgccttgacg ggaggcatgc ggatgaaatc 8521 aggcccatga aaatagagat cggcgttctt tcacgagccg atggttcatg ttatcttgaa 8581 tggggaagga ataaggtcct tgtaggcgta tttggtccta gggaagctca cccccgtcgt 8641 tcacagcgcg cagatactgc agttatccgt tataaatata atatggcttc tttttccact 8701 gaagaccgag ctaggcctgg acctagcaga cggagtattg aaatttctaa agtttccagg 8761 gaagcttttg agccggtaat tatggcagag ctcttcccga aaactgcaat cgatattttt 8821 gtggaaatac ttcaggctga tgcagggaca aggacagcag caattaatgc ttcaagcata 8881 gcgcttgcag atgcaggcat tcctatgaaa ggcctggtta cttcctgtgc ttttggaaaa 8941 gttgacgggc agatagtgct tgatcttaac aaagaagagg acaattatgg cgaggctgat 9001 tttcctgttg caatgactca ggatggagaa attaccctgc tccagatgga tggaaatcta 9061 actactgatg aaattagaaa aggcttcgag cttgttaaga aaggctgcaa ggaaatcctt 9121 gaaattcagc aggcagtgtt gagaacgaag tttgagactc ctgttgaaga acctgaagcc 9181 aaagccgctg aagaggttga agagactgag cttgaggttg tggaaacgga atcttctcta 9241 gaatatgctc ccgaagcagc agttgtagaa gagattattg aggaagctga agagcctgag 9301 gaaggtatct ctgaagaaac cgttgaagcc tgtgctgtta ataaagaggc tccagagtgt 9361 gaggagctag aaaaagtcat taaagatgcc gaggctgaag tagtagaagg ggaagttaca 9421 gaaaaagtag ttgaagcaga agtcgaagaa gaagctgaag aagaggcatt tgaagacaaa 9481 gctgactttg aatcttcttt cgaggcttct tttgaggaag tttccgaagc tgaggagctt 9541 gaagaacctg aatctgaaga agtcgtttcc ggggaagaag cagaagtcga gtccgagatc 9601 gaggaatctg ctgatgaaga agctcagcct gaagtagaaa ctcagcttga agtagaaact 9661 cagcttgaag agaaggcaga ggttgaagaa gaaactcagc ttgaagaaaa agtgcaacct 9721 gaagaagaag ccggaattga agaagtacag cctgaagaag aagccggaat tgaagaagtt 9781 gcttcagaag aaacttttga atccgagcca gagatagagt ccgaagctga gtccaagaaa 9841 gaggctcctg ccgaacaaac catagaggag tccgaagaag aaaagtgcaa aggaccctgg 9901 aaggtagtaa aagacccctc tgaatcagga agcagaggtg aaaacgatga gtgaagttat 9961 tgctacgctt aagaaggact atatttataa ccttatgatt aagggaaaac gccaggatgg 10021 tcgtggattt aaagatttca gagatatcaa acttgaaaca aatgttatcc cgaaagccga 10081 gggctcggca aaggtaacgc tgggagacac ccaggtcctt gtaggagtta agcttcagcc 10141 aggaactcct tttccggatt ctcaggacga aggcgtaatt attactaatc tggaactcaa 10201 tcctattgct tccccggaat ttgagccagg cccacccaga gaagaagcaa tcgaaatggc 10261 aagggttgta gacaggggaa tcagagaatc aggcgcaatt gatataaaga agctttgcat 10321 aagcgttgga gaatccgtct ggattgccta tatagatgtc catgtcctca atgatgatgg 10381 aaatatcatt gatgcatcca gtctcgctgc tattgcggca cttatgacta caattgtccc 10441 gaatgagcag catggaatcg gtgcggacgt acctcttgca atgaaagaga tgcctgttgg 10501 cgtgactctt gccaagatcg gctcaaagct gatggtggac ccgtcactgg atgagggagc 10561 ggtttgtgag acaaaattaa ctgtggtctc aagttcggat ggatccgtcg caggcatgca 10621 aaaaatgggc actgttccgt tcaccgaggc tgaggtgctg gaagcaatag atatggcatg 10681 tgaaaaggca gctgagatca ggaaacttta cctggaagca ctggtataaa aggaatgatc 10741 aggcaggatt aattaaatat aaatattaaa tgcagtatta cggtttaagt atacgtgcaa 10801 taagtggtta tagaacctgg taatctggac ctcagggatc cgacctgcga gccagcaggt 10861 ttcgaattca atcacttaga attaaacgtt tcattttagg gagttttaac gatggcaaaa 10921 aagttcacta agaaaggaag gatttccagg tcagcaggca gattcggtgc cagatatgga 10981 cgaaaagaca gaaagcttgt tgcagacctg gaagaacgca tgcgagctcc gcacgtatgt 11041 acaaaatgtg ccaggcctac cgtgaagaga atcgggaccg gcatctggaa atgcagcaag 11101 tgcggacaca ccttcgctgg cggaacttat attccatata ccagtgttgg tcagactctg 11161 ctgcgtacta tgaagaatgt cgctgaggca aagtaatatc tcaaggttgt ggttgtatgg 11221 gttataaatg cactcgatgt aaacagaaag tggaaatcga ttacgagtac acaggcataa 11281 ggtgtccgta ctgcggacac agaatcctgg tcaaagagcg tcctacaacc attaaacgca 11341 ttaaagccga gtaaggatgc tggtttaaac ctagctgaca agcagaaaag tattagataa 11401 aaaatgggct tctgtgaatg taagccctcc tatctaataa ttcaatgcgt agaattcaat 11461 gcgtaggaca ctgttttatt caaaaattat ttcgcttttt taatttcttt tattgcagtt 11521 atattatagt atgcaggtga cacgttattt tacttaaact ttcgatatct ttcttttata 11581 tggtcgttct aaagtactaa aatgaaattg aaatttactc agtgtttagc ttttcttaac 11641 cgtttgcgtc gcctgttgtt gcattatata tcgaactctt aagtatttct gaatctgcga 11701 actcatttca ggatgaaaaa cattagatct gtataatatt agatctgtat aatattagat 11761 ctgtataata ttagatctgt ataatattag atctgtataa tattagatct gtataatatt 11821 agatctgtaa aaatagatta cccaatctac caaaatatat aaccttacaa aaatattgac 11881 acattgcctg aaagtttact ttgaaccttc gagaccgggt aagtaacctg aagcagaatt 11941 aaatttttct gaatcgtttt gaagctttcg cgagtttttt ttcacatccg cattctctag 12001 ctcgcacctt gaaagaacga tgttgatact tttttccaga tctttttcat cgaaaggttt 12061 caaaatacat ccaaacccca tattccagat ctgttcgaga agcttacggt ccgaacaggc 12121 cgtaaggtaa acaactggaa taccgaaccg ggaaattatc tcctttgatg cttctatgcc 12181 attcagggta ccttttaaca taatatccat aagcacaagg tcaggtcggg tgctttcggc 12241 tttgctaatg gcctcctcac cggatgaagc tatacccgta acagtacatc ccagattctt 12301 cagcatcatc cgtattccca ttgcaacaat ctgctcgtcc tcaacaatca gaattctttc 12361 ttttaccatt tactgctgca cctttattca gcctcggaga gctgggtttg aaacaggttt 12421 cctacctttt tcaggattaa gttcctccaa tctgtcaatg aaattatagg ccggaacaga 12481 aacactcgag cacattcgat ctctaagtta tgaaaacaaa ttcaagaatt tcactaacta 12541 tgatttcact aactatgatt tcactaacta tgatttcact aactatgatt tcactaacta 12601 tgatttcact aactatgatt tcactaactg tttgatttca ctaactgttt gatttcacta 12661 actgtttgat ttcactaact acttgatttc aataattatt cacaaacctg ggactaaggg 12721 caaacttctc tattgttacc tgcattgaac cctatataaa ttaagatata taacccaccc 12781 catatggcac ttacaaaaga gcaggaactt taagctgaca ctgtccatgg caaaggggaa 12841 gaactttgtc cgggttcaaa ggatattttg atccaattaa aaattttaat tatactgtca 12901 gcaaaaattg aatgagaaat aaagaaaaag acagcgaaga ataagagagc tcctttgctt 12961 ttaaagaaaa agaagtaaac tttggcagtc cggaagattt tcaggatttc ttaacttgac 13021 tttgtcacat ttccttttca catcaaccgt gaagtcctaa tttttcctct ataaatttgg 13081 tttagtgaaa caaataacag atgattttat caagtcaaat aatatttctg tagaaaaata 13141 catttcagag aaacatcttg aatcctattt ccaaacgaaa actcgttgtg ttgtttcaac 13201 cggcattgat taccttaatg gtttgtttct tctcccctat aggaaaaata tgagaaaaat 13261 ggcaatctat tgttgtaaat gctctaacaa ccaatcacta agccatttta tctcaacttc 13321 tccttggcgt cctgcagatc tcctcaaatc tgttcgaaca tatgccatta aaactatagg 13381 caaaaatggt gttcttatac ttgacgaatc aagcataaaa aaatctggaa atagttctgt 13441 tggagtttct catcagtatt gcggcaacct tggaaaaaag aataattgtc aggttggtgt 13501 gttccttgct tattttaaga aacagaagag aatgttgatt gatgagagat tatatctccc 13561 acaaaaatgg attaatgaca aggcacgttg tttaaaggct aaaattcctc ctgagaaaat 13621 aaagttccga accaagcatg agcttggcct tgaaatgatt gataacgcaa tagaggaagg 13681 tattcctttt tcctatgtta caatggatgg attctacggt gaaaatccgg agttattgac 13741 agaacttgaa aatagaggct taacttttgt tgcagatgta gcggtcgata ctcttgttta 13801 tattgaggaa ccattagttg ggattcctga aaaaaaggga acaagaggaa gaaaacccac 13861 aatttctaag gttttgaata cattatcaac aagaattgat tctctttcca gttcaattga 13921 tggatggaaa cttatcaaag ttagaaaaac ggaaagaggg tacaaaaaag tctattttaa 13981 ggctataaaa gtttggagac gtcaaaataa attaccttgt gagaagccat tatggcttct 14041 cataagtaaa gatgtagagt ctaatgacat taaatattca ttatgtaacg cttctgagga 14101 tacttcatta gacgaacttg caaaaatgca gagctcaagg tactggattg agagagcatt 14161 tcaagatgca aaagtatatt gtggaatgtc tgaatacatg gtgagaagct ggaatgcatg 14221 gcatcaccat atggcattgg ttatgcttgc gatgcttatt ctgttgtcgt acaaaataaa 14281 atttatgaaa tttcataaga tttcacttca tggtgtcatt ttgattatga aattccataa 14341 tccattgaag atattaaatg cgggagagct tgcaagaata ttaaatcatg ataatgagat 14401 gagagacaga gcaagagcaa gtagattgaa aggttcttga caaaaaacat gagtaggatt 14461 ttactgaatt ttcgttctgg ttactgataa gtatgcaatt ttgaaagtga aaatgaagga 14521 cattacaaat aattactgta ttgatcaagg tgaataatga gaaaacaaaa atgtcgagtc 14581 aaaaatattc aaaatagggg aatcaattgg aaaaatatgt agtaacaact ccaaaaaaga 14641 gataatctga caatgtcaag ctaattaata gatgatatta ctatttaatc ggaaattaat 14701 atgatgattt tacattttat taacaatgta gcttacgagg ctgtttttac attaattcat 14761 atgagagaaa gcggcaagga aaattgcaag gataatatgg caccttatta taaatgacga 14821 gatgtatgaa gactagaccg gatatcaacc ggatatcaaa aggagatatt caaaagagga 14881 agattgttga gaccacgata ttctcggttg atgaatgaat taaaataatg agttaaataa 14941 ccgtaattat gggataaaat gaagaaggga gtatgtgcaa aacaaataat cacgtacctt 15001 catgccaaag aaaatggaaa atttataaaa aaatagacaa gtttaaagaa gaaagaataa 15061 ttctggcaaa agaatacagt aagacatgac aaaaatattg taagttcgcc agaattgccg 15121 gatgcccgct ctttggtttt tacagttaaa gctgagggac tggaagagcc tgtatctcga 15181 ttatcttccc ggatgtaact tttgaatcag gcgaggcaag ttccagcacc ttttctgcga 15241 tgtgctctgg cttgagcgaa ggtctgtccg aaaagagtga tctgtacata tccgtatcca 15301 cagcgcccgg gcagattgca tagactttta tttctccttc cagctcggca gcaacggact 15361 ctgttatgcc gtttactcca aacttcgaag cacagtatgc agaaaaatcc ggaagcccgt 15421 gtaatcctcc tactgaagat atattgatga ttttcccatt attgctctcc ctgatgtatg 15481 gaattgcata ctttgtgcag agaaaaactc cttttaagtt ggtgtccatg gtttgattgt 15541 actcttccag ggtggtatct tccagctttt ttttgtaggc cactcctgcg ttgttgacaa 15601 gaatatcaag cctgccgcat ttgtcaattg tcattgaaat caggcgtctt acgtcctcct 15661 cattctgcac gtcagcctgg acagccatgg ctttactgcc cattgctttt aatttattta 15721 ccatctcttt gatttcactc tcattccttg ctgcaataac gatgtttgct ccctcttttg 15781 ccagagcaag gcagatagct cttcctatcc ctttgctccc cccggttaca agagctgttt 15841 gacctgctaa actcattact atccctttta tcagtttatt tttatctaat tgttttttat 15901 taaataatag ataaaacgga taaaaaaagg gatatatttt tggaaattaa gtttctgaaa 15961 agaagttctt ctcgtgagaa tgaacttttt gttattctca atttcttcgg ttgtcagcct 16021 cttatgatag gtgtaggact tacgcacttc aagtacggaa tcataagttc attaggcatt 16081 gtaattaaaa ctcgtgtttt agatagtttg aggtttaatg ctattgattt atcagttcaa 16141 ctgcgtaagt cctaaggtgt agtgatgggc actcaagcct aattttgact tgattaattc 16201 tcataccttt taagatcttt ttccgcctgg gttgaccagt cccaaactcc caggtttgac 16261 ctcgtggcaa gcctgtaaag agctacaagg tacccgtcct ggatatgcct gctcaaatct 16321 ggggcaattc tgcattggtt aagtatatag aagatagtgc ttgttgaaag aacaatccca 16381 agaagcacac gttttgaggg ctatagctct cgatttttat cctcttttga aacctgtggt 16441 ttcattgaga gccctgtatg aaaatcaaaa atagagagct ctataaagag gctaccctac 16501 aagggcaaca attccgaaaa tcaagtgtaa tatatgttga aaatcaaatt cgttttagaa 16561 tctgcaattg tttgtattat atataatttt ggtatgaggc ttcgagctaa tattcacgaa 16621 cttgtcttag atatatgaat atgtttgtaa aggtatacag ggtatcacta ttagatattt 16681 tttgcataaa acatataaag aataattcaa ttattgtaaa gtgaaataga aaatggacat 16741 tccaaccgct acggagatca cgctgttaca tgtatgggtt ctaaaaaata atgggttcta 16801 aaaaataggt tcaaaagctt atatttacat aagagtttat gtttacataa atgattgttg 16861 ggattcaaat atttattata ttacttttgg aaattggaaa aaggcaatgg caacgagggt 16921 gagaccttaa gagggtgaga ccttaattac catatgtatt ttttgagatt gataactatg 16981 gatctctcac aaattaatac aaaattaata attatcttat tgttaatttt tgtcgcctca 17041 atattttaca ctttcaatgc aaagtatagt ggaatatatc ctgaaaaatc tcttgacaat 17101 attagcaaca attcaataaa tgctgacttg cattccggag agccggtaaa aaataatctg 17161 gataatattg acaatgatcc gatagatgct aaaatatacc caggagattc agtacagaac 17221 gcaataaaca ctgtgagttc tggtggcact gttattgttt acccagggtt atataaggag 17281 aatttagttg tagacaaacc gctgaaggtt ataagctcaa acgaaggagg atctgcatat 17341 gcttctattc aagctgcaga cccagaaaaa gatgtattcc acataactgc ggataatgtg 17401 acaatcagcg gcttcaatat aactgggtca caggataaag ctggcatcta ttatagtggg 17461 tctggtggca acatcactag aaataaacta agttataaca attatggagt ctactttaac 17521 gactcaaagg tgaatatcct ggaaaataat gaagtgaata acaattcact tggaatctat 17581 ctaaggaatt ctaataataa ccaattaaaa agtaacaata tcacaggcgt tgggatattt 17641 gttggcttag ataataatgc aacaggaatc tatcttgaag attcagacaa caataaatta 17701 atgagtaaca ccatagcaaa gttatgggat ggcgtgaact tcactgagtc ttctaataat 17761 gagctaaata ataattcgat tttacataat tatttcagcc tcagtctcat taactcaaat 17821 aataataaag ttttgaataa cactattgtg agacgtggat attcattttc agttgtcctt 17881 gccaattctc aaaataacac gttacaaggc aacaataaaa atttgaatac tgacttcaaa 17941 atatactata gctttaaaag cacaaacaat acgctagaag gagaactcta tacatcaaac 18001 gagcagggta ctggcggcgt ttttagagta atataacgaa aaagtttacc tataagtaaa 18061 gaagttattt tcctcatgta tttccaataa tgacttgctg ctttcagtga atcatgttgc 18121 tatcaaaggc ttgcgcgtgg atgattatag gcaaccgcta cgggtgacaa ttaacagtca 18181 aaacccggtt aatattgttc gaaaacctga catt //