LOCUS NC_004342:5 18263 bp DNA linear BCT 18-AUG-2011 DEFINITION Leptospira interrogans serovar Lai str. 56601 chromosome I, ACCESSION NC_004342 SOURCE Leptospira interrogans serovar Lai str. 56601 chromosome I, COMMENT locus start: 1648977; locus end: 1667239 FEATURES Location/Qualifiers source 1..18263 /organism="Leptospira interrogans serovar Lai str. 56601 chromosome I," gene 0..941 /gene="hlpA" /locus_tag="hlpA" /db_xref="1648977..1649918" CDS 0..941 /gene="hlpA" /locus_tag="hlpA" /product="hemolysin hemolytic protein hlpA" /translation="MSLAPIALFVYNRPEHTKRTIDSLSNNDYAEQSELFVFCDGPKP NTNMDKIREVRSIVKQATGFKKVIVYEKENNVGLAKSIISGVTELVTKHGKIIVLEDD MITSKYFLTYLNHGLEYYENLNQVVSIHAYRLPFTAKTPETYFLRGADCWGWATWKRG WDLFEVDGQKLLDKLISEKLIYQFDMQGSYPYTQMLKDQIAGKNDSWAIRWYASTFLQ NKLTLYPARSLVFNIGLDASGTHCEVTNEYDVDLSSIPIRIETIQIEENVYIRNLYRD YFRKLSQSDLRTRIFGRLKQLLERIKTRIWPDKSNLL" gene 1044..1265 /gene="" /locus_tag="" /db_xref="1650021..1650242" CDS 1044..1265 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LVRIEKFYIKFKKIRVSPKNLSERPKTRPGKSSECFSKVYRYLG RSSRRETLSFHRSIEKCLLSFSNDFSEGN" gene 1642..2535 /gene="" /locus_tag="" /db_xref="1650619..1651512" CDS 1642..2535 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNSILKTYIKKIAYKFSPPIFWDLLKFVRRQFHKRVKFKIHGKL FYDDFNGIYKTWEEASQFCGSYDSDLILEKCKQSLLKVKRGEAVYERDSVVFEKIQYS WPLTSGLLYAATMSNSKLNVLDFGGSLGSSYYQNRNFLKGIKNLSWNIVEQPNFVQAG KKYFKDDILNFYDSIESCINDKNQKINVFLASSSFPYIKDPFVLIKKIIQYKFAYIII DRTYFIDLPKSIVSIQSVPSEIYEASYPAWFFNFEEFISLFQTMYHLVTDFESYLQAT GRLEGLSTQEKGMIFELKKTL" gene 3176..4198 /gene="" /locus_tag="" /db_xref="1652153..1653175" CDS 3176..4198 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKYLCTLFDFNYLPLGISLYESIRLHFGDFHLWVLAMDDKTCTF FKENSFDHVTVLSLSDIESEDVLVAKGNRTWQEYCWTLSPVLPSYVLAKNRAIDHITY LDSDIYFFSDVEPVYNEIGKYSVMIIPHRFPDRLKYLEANGIYNVQMVYFKRDEIGMK CLNRWREQCLEWCYNRLEEGRLGDQKYLDIWPQAYKNVCVLKNEQAGVALWNVEKYKI ELKNGRIFIDDVLLVFYHFHMFKFYAGNIYGTGISDYGLNYKTLKIIYEVYVEQLIKV VSRFDLKLRNLNILEMCNMIEKKNFYSYSFFNKFFWNVFLYGFVVLKKILKIGRNSLL KVYPEA" gene 4348..4767 /gene="" /locus_tag="" /db_xref="1653325..1653744" CDS 4348..4767 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MDEIIVKNSGYINLKKIRDDRDGNLIILESLKDIPFEIKRVYYI NNLENSVSVRGQHAHKEIEQAIFCVSGSFTLRLDDGKTKQEILMNKDNVGVLLGKMLW HAMENFSSGCILLVAASDYYREDDYIRNYSDFIRLAG" gene 4781..5872 /gene="" /locus_tag="" /db_xref="1653758..1654849" CDS 4781..5872 /gene="" /locus_tag="" /product="probable DegT/DnrJ/EryC1/StrS family protein" /translation="MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQF AEYNGNRYCIGVGNGLDALILALKALGLEKNSEIIVPSNTYIASILAILHAGLKPVLV EPDIRTYNIDPQKIEEKINFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS HGALYKNKKTGTFGEMSGFSFYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIK YKNDLVGYNSRLDELQATILSIKLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEV YDVYHIFNIRHTKRDDLRDYLLKNGVKTEVHYPIPPHKQIAMKDVILYAEGEFAISEE IHRTTLSLPISTFHTEEDIYKIVEIMNRF" gene 6015..6812 /gene="" /locus_tag="" /db_xref="1654992..1655789" CDS 6015..6812 /gene="" /locus_tag="" /product="glycosyl transferase" /translation="MTAKEPKISIITINLNNLEGLRKTLESVKSQTYTNFELIVVDGG STDGSFEYLKSNLDLIKKFISEKDKGIYNAQNKGILLSKGEYLVFLNAGDTLLQKNIL LEISKFLDQDVDLVYGNILIDSKDNGIIERKYPDRLNYFYWSIKSLCHQAVFIRKSLF DLYGYYNEEYLFAADFEFFHRFWFNKNIKIKHASVFVTLYDFNGVSAQPKNRKRIAEE YQKIKKKYFPIWAYVVYKVNSYLLERFSNTFVWNLLFKFYRFINPKR" gene 7322..8143 /gene="" /locus_tag="" /db_xref="1656299..1657120" CDS 7322..8143 /gene="" /locus_tag="" /product="glycosyl transferase" /translation="MYNTPIVSVIIPCYNYGKYIEQAIQSILEQSYKNWEIIVVDDGS DDEYTIEKLEELKKEYAVIKIDRSGPAVARNVGIEAAKGKFILPLDSDDTIHSDYLLE AISAYEKKPSLGIVYCEAEFFGSMKGRWNLPKYSFPEILLDNCIFVSAVFRKSDWKEV GGFNGNMKNEWEDYDFWLSLIEKGRDVYKIPRVMFYYRRGHVSRSSRSIETYLPLYLQ LFKNHKRLYTENIEVLFKRHLKARELEEQFSILTKNPIIYGIVRFLVSCLKFFAK" gene 8857..10605 /gene="" /locus_tag="" /db_xref="1657834..1659582" CDS 8857..10605 /gene="" /locus_tag="" /product="glycosyl transferase" /translation="MKTLILKIDEFYRKLKYLFRQYQYYFRIYKDSKIPSEFVYSPLV SILVPVYNTRLDHLKEMVDSVTSQSYTNWELILIDDASPDENPGNYLKERSKTDSRIL YFRLNKNGGISLTTQKAFEYSKGEYIAFLDHDDRLSKNALSIVVKTLQEEKNRPEFLY SDEVFQSKIPGIFSLSVKPEFSPEKLISHNYICHFVVVSKNLIYRMGGIREGYDGSQD HEFALRASRFTNQIKKLPYFLYIWRLHGGSFSRKKAEICEASSKKAILEHYNDKKEEV EKIVSGNYPFTYHVFRKLKKKYIVSVIARNCSDLNWVFFRESIQNFLSFPLDVKIELW LPEQSVLKQIQEEKNIKLEYYKLFNNSLVSRELNQIVAATKGDFVFFWNPGFQPNNQS WLYELLQHAQFSEIGAVSPIVLNKKKELVYSSLILGKYGFIGRSRNNLTVSKTKIWSG EWVEKNVSAISGNCLLISKKSWNVINGLDESFQKYYWDIDLCLRLRRAGFRLVSNPFS EFIQTISDYKIFKELNPKFLESVNDRKKLITKWGVFLDVDDFYSSHSDLVGKDMIPKG LNHGFLEWYWKKKWSI" gene 10801..11361 /gene="rfbC" /locus_tag="rfbC" /db_xref="1659778..1660338" CDS 10801..11361 /gene="rfbC" /locus_tag="rfbC" /product="dTDP-4-dehydrorhamnose 3,5-epimerase" /translation="MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQF SQDNHSRSSRGVLRGMHLQIPPYDQGKLVRVVRGKVIDVVVDVRVGSPNYGKWLSVEL SEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWL SDSEFIVSQRDQVTPFFADFKSPFVY" gene 11365..12285 /gene="rmlD" /locus_tag="rmlD" /db_xref="1660342..1661262" CDS 11365..12285 /gene="rmlD" /locus_tag="rmlD" /product="dTDP-4-dehydrorhamnose reductase" /translation="MIYYTGKNGQLGWELAERFKSNGLEAVGFGREEWDLADLDSAAR ILKDSPRILVHCGAYTAVDKAESDSENAYKINSLSVKKISEECLKRKIHLIYVSTDFV FDANSETIGDTIRFWKPDSTLSPKGIYGLSKAEGEKWIRNTFVDSKQANIVRTSWVYS SHGNNFPKTIVKLLQDSNRHELRVIEDQLGRPTWAGRLADFIIFLIYGILKGESYPEI LHFSNSGVASWYDFALAVRDFSHSFSLIENLKPIYPIPTEGYPTPAPRPRYSILDLEE TRKIFGVVPHWREDLTLCLKELAEVSGKKV" gene 12222..13331 /gene="rfbB4" /locus_tag="rfbB4" /db_xref="1661199..1662308" CDS 12222..13331 /gene="rfbB4" /locus_tag="rfbB4" /product="dTDP-glucose 4,6-dehydratase" /translation="LERGFNPLSERTCRSFRKKSMKKILVTGGAGFIGSNFVNLILND TKEYQVVVFDKLTYAGNLRSLESWKKDSRFIFVKADIANKEEVSSIFQEHKFNYIAHF AAESHVDRSISGPEEFIKTNVLGTFYLLDAARLQWNGSYEGKKFLHVSTDEVFGTLGD SGYFTEETPYAPNSPYSASKASSDHIVRSYYHTYHMPVVTTNCSNNYGPYHFPEKLIP LMILNCLQGKPLPVYGDGKNIRDWLYVKDHCEALRVALFQGLSGETYNIGTRNEKKNI DIVDSICSIMDELHPSGAPHSKLIQYVKDRPGHDFRYAIDPSKIEKELGWKPKFAFES ALKETVRWYLENESWWKEILSGQYKEYYENQYEKR" gene 13332..14216 /gene="rmlA" /locus_tag="rmlA" /db_xref="1662309..1663193" CDS 13332..14216 /gene="rmlA" /locus_tag="rmlA" /product="Glucose-1-phosphate thymidylyltransferase" /translation="MKSRKGIILAGGSGTRLYPVTYVVSKQLLPVYDKPMIYYPLTTL MLAGIKEILLISTPQATPMYKELLGDGKQWGISIEYAVQPNPGGLAQAYWIGENFVNG HPSVLILGDNIYFGHNLASLLENASKKENGSTVFAYPVHDPERYGVVEFDSERRAVSI EEKPSKPKSNYAVTGLYFYDEEVVNIAKSIKPSARGELEITDVNRIYLERGILNVQVM GRGYAWLDTGTHESLLEASVFIETIEKRQGLKVACPEEIAFRKGFIDGSQLEKLISPL KKTGYGEYLVKVLNEKIY" gene 15198..16172 /gene="" /locus_tag="" /db_xref="1664175..1665149" CDS 15198..16172 /gene="" /locus_tag="" /product="glycosyl transferase" /translation="MKYYNIITITYNSKKYISALDQSMQLPSNWTWIIWDNDSKDGTQ EQLKLLSKKNKRSIHFSSKNLGFAGGNNEAIKVAPKSDWTLLINPDSRLSDNFFSECE RTLESKGKEYSIISFLMLKDNQEEKKLIDGAGDIYHVSGAAWRRGYKRILSEEYLRES EIFSACGGAMAIRTEVYERIGGFDSDFFCYMEDVDLSFRARLMGERVLFSPNIKVYHH GFGSTEEKSTFSLYYGLRNALVVYWKNMPLPYALRYILHHILFFGVSICFHTVFTSPK ILGVPFGFLRMLPGIIRKRLDIQNIQGNKFSKTLMWMNRGWFTPFRKK" gene 16177..17088 /gene="rfbF2" /locus_tag="rfbF2" /db_xref="1665154..1666065" CDS 16177..17088 /gene="rfbF2" /locus_tag="rfbF2" /product="dTDP-rhamnosyl transferase rfbF" /translation="MPEKFSPLAVIVTFNPDINLTYKNVQNLNLNSVPVLIVDNQSKN VSAIRSKIKKQNFLIENESNLGLGFALNRGIEYAQSNLYTHVWLFDQDSFLETSAIRL FLQKIREYEIQKFPNEKVASYGPNIFDTIKNRNIYGILKDETGILNAKFLITSGSFYS LEVLKEVGLMYQDFFIDYLDYEWCFRANDKGYVHKIISDVKMKHSIGSDSRSIFGIFK VAIHSPFRWYFLFRNGIYICKMPHIPFRFKLEVVLKTIFRFLILPIFSDSKYQTYLHI LCGICDGITGRKSSFYKHLVGETFSTT" gene complement(17173..17370) /gene="" /locus_tag="" /db_xref="1666150..1666347" CDS complement(17173..17370) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MWELTQFAGFTVKFKMWELTQFAGFTVKFKMWELTPKSGLGIIF ENFLIFIKLIVNFGYKCQASE" gene 17414..18262 /gene="" /locus_tag="" /db_xref="1666391..1667239" CDS 17414..18262 /gene="" /locus_tag="" /product="glycosyl transferase" /translation="LEFGITVSIVLYKPNVSILKESLLSLLNSITYQISNASKSILYK IEILDNTPQYGEEVKNIVNDLEKKFSSKNRVKFEYFHFPENLGYGVANNRSILKSNME FHLVLNPDIKMIPETLDLCVRYLEEHPGCDAVVPSVWDWESDSNKKRNMQFLVKSYPT VFVLFLRSFAPDILKKVFRKYLDQYDLRDKDWNQIQEDVSLISGCFIFARTKSLKQIG GFDERFFLYFEDFDLSMRLKRKDYFPKIQIYHKGGNSSKKGFLHVRLFVISAIRFFMK FGWKLI" ORIGIN 1 atgtcattag ctccgattgc actttttgtt tataatagac cggaacatac aaaaagaacg 61 atcgattctt tatcaaacaa cgattatgcg gaacagtctg aattatttgt attttgtgat 121 ggacctaagc ccaatacaaa tatggataag attagagaag ttagatcgat tgtcaaacaa 181 gcgactggtt ttaaaaaagt tatcgtttat gaaaaagaaa acaatgtagg tttagcaaaa 241 tctattatat ctggagtgac tgaactagta acaaaacatg gaaaaattat cgttttagaa 301 gacgatatga taacttcgaa atattttttg acttatttaa atcatggatt agaatattat 361 gaaaatttaa atcaggtagt ttctatacac gcttatcgat tgccgtttac cgcaaaaact 421 cccgagacgt attttttaag aggtgctgat tgttggggct gggcgacttg gaaaaggggc 481 tgggatctat tcgaggtcga tgggcaaaaa cttttggata aattaatttc agaaaaacta 541 atttatcaat ttgatatgca agggtcttat ccttataccc aaatgttaaa agatcagatt 601 gcaggtaaga atgattcctg ggcgataaga tggtatgctt ccactttttt acaaaataaa 661 ttaactttat atcctgcaag atctttagtg tttaatattg gattggatgc ttccggaaca 721 cattgtgaag ttacaaacga atacgatgtg gatttgagtt cgattccgat tcggattgaa 781 acgattcaaa ttgaagagaa cgtttacatt agaaatttat atagagatta ttttcgcaaa 841 ctcagtcaat cagatttaag aactcgaatt tttggtcgat tgaaacaact tttagaacgt 901 ataaaaacga gaatttggcc agacaaatct aatttgctct aggatttaaa ttcttaaatt 961 gtgaaatttt atcttctgga attgttttga gttttatagt ttatttataa aaacaatata 1021 tataaaaatt agaatggttt tgctttggta aggatagaga aattttatat aaaattcaaa 1081 aaaataagag tctctcccaa aaatctgtcg gagcgtccta aaacgcgacc cggaaaatcc 1141 agcgaatgct tttctaaagt atatcggtat ttaggaagaa gttcaagaag agagactctg 1201 agtttccacc ggtccatcga aaagtgtttg ttgagttttt cgaacgattt ttcggaagga 1261 aattgagttt cacaaaaatg tgagacccgt atagaaatta taataataac aaaagagtat 1321 taaaaaacta taaatccttt atagcgattt ttgtgagaac tatcatattt tgtttaagat 1381 tcaaaggcga ttgattttaa ggttttggga caaactctaa atataaaatc tttgcaaaaa 1441 cactgcttct aaacaccgta aaaattatag aaattttcaa attttggctt tatttagaat 1501 ttgccgattc attgtttgta aattttagaa agactttgaa aatttataat gtttaaaact 1561 tggatataaa atagttataa ttttttaaaa aatacgctct tattctaaag aatacgaaag 1621 taaaattttt agattttttc ttatgaattc aattttaaaa acatatataa agaaaatcgc 1681 atataaattt tcacctccca ttttttggga tttattaaag tttgtcagaa ggcaattcca 1741 taaacgagtt aaattcaaaa tacacggcaa gcttttttat gacgatttta atggaattta 1801 taaaacttgg gaggaggctt ctcagttctg tggttcttat gattctgatc taattttaga 1861 aaagtgtaaa caatctttat taaaagtaaa acgaggagaa gccgtttatg aaagagattc 1921 agtcgttttt gaaaaaattc aatattcttg gcctttgaca tcagggttac tttatgcagc 1981 gactatgtcc aattcaaagc tgaacgtatt agattttgga ggttctctag gaagtagcta 2041 ttatcaaaat cgaaatttct taaaaggaat taaaaattta tcttggaata tagtagaaca 2101 accgaatttt gttcaagcag gtaaaaaata ttttaaagat gatattttaa atttttatga 2161 ttctattgaa tcctgtatta atgataaaaa tcagaaaatc aatgtattct tagcttctag 2221 ttcttttcct tatataaagg atccgtttgt gttaatcaaa aaaattattc aatacaaatt 2281 tgcttatatt ataatagata gaacttactt tatagattta cctaaatcca ttgtatcgat 2341 tcagagtgta ccttcggaaa tttacgaagc gtcttatccg gcttggtttt ttaattttga 2401 ggaatttatc tctttatttc aaacaatgta tcacttagtt acggattttg aaagttattt 2461 acaggcaacc ggtagattag aaggtctatc aactcaagaa aaaggaatga tttttgaact 2521 taagaaaact ttgtaaagtt atattaaatt tttaaaatgt tttgaattta tgttcaatct 2581 tttattatag aaacctatgc actggatgat cttagaaaaa acagtttaaa aattcataat 2641 gccctgttgt gtagggttgt tataatgttt tgtaaaagct tgtcctaaag ccttaaaatc 2701 tggagactac tacgaaaatt agagctactc gaaggtttgc aaattgctaa tataatctaa 2761 tttgtagaaa ctgctgtatt ttattaaaaa tttctaaaaa attatcgcct aaaattcttt 2821 aaggttttgg gacaagttct aagtaaaaat tgatgcaagt tcatgaaagt ttaatttcaa 2881 ttcatttcat aaacttttaa aacgttttaa ataattttta aatgaataat agagttattc 2941 aaaaattatt tttcttttat ttatttttca ttaagttgag tgggtgattt cgttttgcta 3001 agaattatct taaaagtgct ttgtctttgt ttaacatatt gactctgatt attctaagat 3061 atttttgaga tagtttctaa tatcgaatct caatagtttg aatgtagctt ttgtaatata 3121 tattttaata tttaataatg tatttatgtt atacatttaa aaataaataa ctgccaatga 3181 aatacctctg cactttattc gattttaatt atttaccctt gggaatatct ttatacgagt 3241 ctattcggct gcattttgga gattttcatc tttgggttct tgcgatggac gataagactt 3301 gtactttttt taaagaaaat tccttcgatc atgttacagt gctttcgtta agtgacatcg 3361 agtccgaaga tgttttagtg gcaaaaggaa atagaacctg gcaagaatat tgctggactc 3421 tttcgccagt tttaccttct tacgtattgg ctaaaaatcg agctatagat cacataacgt 3481 atttagattc agatatatat tttttttccg atgtagaacc agtttataat gaaatcggaa 3541 aatattccgt aatgattata ccacaccgtt ttccagatcg tcttaaatat ctcgaagcca 3601 acggaattta taacgttcaa atggtatatt ttaaacgaga cgaaatcgga atgaaatgtc 3661 ttaatcgttg gagagaacaa tgtttggaat ggtgttataa ccgattagaa gaagggcgtt 3721 tgggagatca aaagtattta gacatatggc ctcaagctta caaaaacgta tgtgtattaa 3781 aaaacgaaca agcaggagtc gctctctgga atgtggaaaa atataagatt gaattgaaaa 3841 atggaaggat ttttatcgat gatgttcttt tagtatttta tcattttcat atgtttaagt 3901 tttatgcggg aaatatctat ggaactggga tttccgatta cggattgaat tacaaaactt 3961 taaaaattat ttatgaagtt tatgtggagc aattgatcaa agtggtttct cgttttgatc 4021 taaaattaag aaatttaaat attctagaaa tgtgtaatat gatcgaaaaa aagaattttt 4081 attcatattc tttttttaat aaattttttt ggaatgtttt tctctacggt tttgtagttt 4141 tgaaaaagat tctaaaaatt ggccgaaatt ctcttttaaa agtttatccg gaagcttgaa 4201 atatcgattt tgaatcttta gataaaatat gtaggttctg taaattacat cgagtaaaat 4261 gaaatcttgt tctgatacag attaaaatat tcaattctga ttttgtgtag ttttttagca 4321 aaagtattgt ggaaattagg ttattcttat ggatgaaatt atagtcaaaa attcaggtta 4381 tataaaccta aaaaaaatca gagacgatag agacggaaat ttaattatat tagaaagttt 4441 gaaagatata ccttttgaaa taaaacgagt ttattatatt aataatttag aaaactctgt 4501 aagtgtaaga ggccagcacg ctcataaaga gattgaacaa gcgatttttt gtgttagcgg 4561 gagttttacc ttgagattag atgatggaaa aacaaaacag gaaattttaa tgaacaaaga 4621 taatgtggga gtccttttgg gaaaaatgct ttggcatgct atggaaaatt tttcttccgg 4681 ttgtatcctt cttgttgccg cttcggatta ttatagagaa gacgattaca taagaaatta 4741 ttctgatttt atcaggctgg ctggttgaaa aaaaattaaa tatgattgaa tatgaaaatt 4801 tacgtttagc gaatgaacgc ttttttgacg agtataaaac taaactttta gaaaccatag 4861 aaagcggatg gtatatatta ggaaaagaag tttctaactt tgaaagtcaa tttgcagaat 4921 acaatggaaa tagatattgt attggggtag gaaatggtct agatgcgttg atactcgcct 4981 taaaggcgtt aggtctagaa aagaattctg aaattatagt tccttcaaat acgtatatag 5041 cttctatatt agcaattttg catgcaggtt tgaaacccgt tttagttgaa ccagatattc 5101 ggacctataa cattgatccc caaaagatag aggaaaaaat aaattttaaa acaaaaggga 5161 ttttgatcgt acatctgtat ggtaaacctt gtgaaatgga ttctatttta aagataaaag 5221 aaaaaaataa tctgtttcta gtggaagatt gtgcgcagtc tcatggggcc ttgtataaga 5281 ataaaaaaac gggaacgttt ggagaaatga gtggattcag tttttatccc actaaaaatt 5341 taggagctct tggggatgcg ggtgcggttg taactgataa tgatttatat cacgatgaga 5401 ttcggaaatt aagaaattat ggttcttcaa tcaagtataa aaatgatttg gtcggatata 5461 actctcgttt agatgaatta caagcaacaa tcttaagtat caagctgaaa catttggatg 5521 taatgaacga gcataaaaga agtttggcga aaatttatct agaaaatcta aaagaagatt 5581 ttataaaacc aatagtcgac gaagaagttt acgacgtata tcatatcttt aatattcgtc 5641 atacaaaacg tgacgatttg cgagactatc tgttaaaaaa tggcgtaaaa acagaagttc 5701 attacccaat tcctcctcat aaacaaatag cgatgaagga cgtaatctta tacgcagagg 5761 gcgagtttgc gatctcagaa gagattcatc gtacaactct tagtcttcct atttcaactt 5821 ttcatacaga agaagatatt tataaaattg tagaaattat gaatagattt taaagaaaga 5881 ttttcattta tcaaaaataa aaatttcttc atataagaat ttcataaaaa ctaaatgttt 5941 gtataaaaat tttactgata ttattagaca catttcaaat ctgatttttg aaaaactttg 6001 aattaatttt tatatatgac cgctaaagag ccaaaaattt caataattac tattaattta 6061 aataatctgg aagggttacg taaaacttta gaaagtgtta agtcgcagac ttatacaaat 6121 tttgaattga tagtcgtaga tggaggttca acggatggaa gttttgaata tttaaaatca 6181 aacttagatt taatcaaaaa gtttatctct gaaaaagata aagggattta taatgcacaa 6241 aacaaaggaa ttttgctttc taaaggagag tatctcgttt ttttaaatgc gggagatact 6301 ttgctacaaa aaaatattct attagagatt tctaaatttt tagaccaaga tgttgattta 6361 gtatatggaa atatactgat agattctaaa gataatggaa ttattgaaag aaaatatccg 6421 gatcgattga attattttta ttggtcgata aaatctttat gtcatcaagc ggtttttatt 6481 cgtaaaagcc tttttgattt atacggatat tataatgaag aatatttatt tgctgccgat 6541 tttgaattct ttcacagatt ttggtttaat aaaaatataa aaataaaaca cgcatctgta 6601 tttgtaactt tatatgattt taatggagta agtgctcaac caaaaaatag aaaacgaata 6661 gcagaagaat atcagaaaat taaaaaaaag tattttccaa tctgggctta cgtagtttat 6721 aaggtgaata gttatttact tgaaagattc tctaacactt tcgtttggaa tttacttttt 6781 aaattctata gatttataaa cccaaaaaga taaaatttgt ttcgaagcct aaaagatatt 6841 aaaggcaatt actcatactt actacgaaga tttatagact aacaccaaaa aacagtctaa 6901 aaatatagta gttcttacaa attgcttcta tcccgaaatt tatagttctt tttgaggaaa 6961 atcctacagt tcaaattttg aataacttag taaaattatt tttatataac ggaatgacaa 7021 taagatatta ctaattttga agctgactct tgtttaaaaa gcaaaatatt gaataattaa 7081 atattctaat atattttttg gatgataaaa gaaccattta aaaatagtag aaagtatatt 7141 agaattattg aaaaattaat tctccatttg tttctatttt atgggaatgg gcaattgaag 7201 cagttttgtt aattggaact agggaatttt tcaacaactc tatttaattt tggaaattac 7261 tacttttaaa aattttttaa acctaatatt tataaatatt tttatttctg aatattctaa 7321 aaatgtataa tactcctatt gtttctgtga tcataccgtg ctataactac gggaaataca 7381 ttgaacaagc gattcaaagt atactcgaac agagttataa gaattgggaa attatagtcg 7441 tagacgacgg atctgatgat gagtatacga tcgaaaaact agaggaactc aaaaaagaat 7501 atgcggtaat taaaattgac cgatctggtc cagccgtggc cagaaatgta ggaatcgaag 7561 cagccaaagg aaagttcatc ttaccattag attcagacga tacaattcat tcggattatc 7621 ttttagaagc aatttctgct tatgaaaaaa aaccatcctt aggaattgtg tattgtgaag 7681 ctgaattttt tggctctatg aaaggaagat ggaatcttcc gaaatatagt tttccggaaa 7741 tacttttaga caattgtata ttcgtatcag cagtgtttag aaaatcggat tggaaggagg 7801 ttggcggatt taatggaaac atgaaaaacg aatgggaaga ttatgacttt tggctttcgt 7861 tgattgaaaa aggaagggac gtttataaaa tacctcgagt aatgttttat tatagaagag 7921 gtcacgtatc tcgctctagc agatctattg aaacgtattt acctctttat ttacagttat 7981 ttaagaatca taaacgttta tatactgaaa acattgaagt tctgtttaag cgtcatttaa 8041 aggcaagaga attagaagaa cagttctcaa tactaactaa aaacccaatc atttacggaa 8101 tcgtaagatt tttagtcagt tgtcttaagt tttttgcaaa gtgaaattca taaataaaaa 8161 agtttaggca tttctgcatc ataaattagt ataaaataaa attcttatat ataaagtaca 8221 ggttggagcc tctccactct aggcaacaaa ttaaaaatca aaagttaaaa aattaactat 8281 tcccgcaatt tgttaactca gctcaatttc taacgccgcg tcccataaaa agtggtgttg 8341 ctgagtttgc ccagattttt tagctttaat tttcttggag tgttttgatt tcaaaattgc 8401 atcttaagtt ttaaaagcta aaatttagag aaaaatacaa ttctgatgaa tatttattca 8461 gagttatata atagaacgtt gtaacgctct atgcaaaaaa ctgtcttacc tatttctata 8521 aaattgagca cataaatatt tattataaag tgtcgtttta cgtaagtttg atttaatccc 8581 atttgaaagc gcttgaagtg taggagaact gagcaaacgt tcctatgaat cacgttctaa 8641 attaaagcta aaggagatat attgtataat gtttcgttca tgcaatttac taactgaagc 8701 tgaaaccgtg ctctggcaac aatgaattca ccagattttt tttacgcaga attcgcttta 8761 ttgaagtgca aactgggtgt tttattatgt agttcggaat attaagtata ttttatatgg 8821 tatcagtaaa aattaaaacg taatgatata attaaaaatg aaaaccttaa ttttaaaaat 8881 cgatgaattt tatcgaaagc taaaatacct ttttaggcag tatcaatatt attttagaat 8941 atacaaagat tctaagattc catctgagtt tgtatactct cctttggtga gtattttagt 9001 cccagtgtat aatactcggc tcgatcattt aaaagaaatg gtagactcag taacttcaca 9061 aagttataca aattgggaat taatacttat agacgatgct tctccagacg aaaatccagg 9121 aaattatctg aaagaaagaa gcaaaacaga ttctagaatt ttatattttc gtttgaataa 9181 aaacggagga atcagtttaa caactcaaaa agcttttgaa tattctaaag gagaatacat 9241 agcgttttta gatcatgatg atcgtttgtc aaagaatgct ttatcaattg tcgtgaaaac 9301 gttacaggaa gaaaaaaata gacctgaatt tctttattca gacgaagttt ttcaatctaa 9361 aattccagga attttttcac tttctgtaaa gcctgaattc tcacctgaaa aattaatctc 9421 tcataattat atctgccact ttgtagtagt ttcaaaaaac ttaatttatc gaatgggtgg 9481 aattcgagaa ggatatgacg gaagtcagga tcatgaattc gctcttagag catctagatt 9541 tactaatcaa attaaaaagc tgccgtattt tttatatata tggcgtcttc atggaggaag 9601 tttttctaga aaaaaagcag agatttgcga agccagctcc aaaaaagcta ttttagaaca 9661 ttataatgat aaaaaggaag aagttgaaaa aattgtttct ggaaattacc cttttaccta 9721 tcacgttttc cgtaaattaa agaaaaaata tatagtatca gtgatagcgc gaaactgtag 9781 cgacttaaat tgggtgtttt ttcgagaaag tatacaaaat tttctttctt ttcccttaga 9841 tgttaaaatc gaactttggc ttccagaaca aagtgtactg aaacaaattc aggaagagaa 9901 aaatataaaa ttagaatatt ataaattatt taataattct ttagtttctc gagagttaaa 9961 tcaaattgtt gcagccacaa aaggagattt tgtttttttt tggaatcctg ggtttcagcc 10021 taataatcaa agctggctct acgaactatt acaacatgcg cagttctctg agattggagc 10081 agtttcacct atcgttctca ataaaaaaaa ggaactcgtt tattcttcgt taattcttgg 10141 taaatatggg tttattggaa ggtctagaaa taatcttact gtgtccaaaa ctaagatatg 10201 gtccggagaa tgggttgaaa aaaatgtttc cgctatatct ggaaactgtt tgttgatttc 10261 gaaaaaaagt tggaatgtga taaacggatt ggacgagtct tttcagaaat actattggga 10321 tatagattta tgtctgagac ttcgaagggc gggttttagg ctggtgagta atccgttttc 10381 agaattcatt cagacgatct ctgattataa aatttttaaa gaattaaatc caaaattttt 10441 ggaaagtgta aatgatcgta aaaaactcat aacaaaatgg ggagtttttt tggatgtaga 10501 tgatttttac tcttcacatt ctgatttagt tggaaaagat atgattccga aaggtttaaa 10561 tcatggtttc ctagaatggt attggaaaaa aaaatggtcc atctaataaa aaatattcca 10621 atattagaaa ttaataaagt atcttggttt taaggagaaa ttttttagaa ttttagttta 10681 tataaagttt aaaaaataaa tttagagata ataaaacaaa aaactcttat tctttatgat 10741 tacgaatttt agtttattag aaaaattgaa tttatattaa ttgaacgtca gttgaagtat 10801 tatgcaattt aaaaaatttc agatagaagg tccagtttta attgaaccta aagtttttgg 10861 agatgaaaga ggtttttttt tggagacctt taaggcatct attttcgaaa aagaaaacat 10921 accatttcaa ttttcccaag ataatcattc tagatcttct cgaggggtat tgagggggat 10981 gcatctgcaa attcctcctt acgatcaagg aaagttagtc cgagtagtga gaggtaaggt 11041 gatagatgtg gtggtagacg ttagggtagg ttcccccaat tatggaaaat ggctttccgt 11101 ggaactgtct gaagaaaata aaaatatatt ttgggttcct cctggatttg ctcatggatt 11161 tttaacctta gaagataaaa cagatttttt atataaagtg accggagaat acagtcctca 11221 gaatgaggta ggaattcgtt gggatgatcc tgcgttaggt attccttgga agacatggtt 11281 gtctgattct gaatttatag tatctcagag ggaccaagtg actccttttt ttgcagactt 11341 taaaagtcca ttcgtatatt agaatatgat ttattatact ggaaaaaacg gtcagttagg 11401 ttgggaattg gccgaaagat ttaaatctaa tggattggaa gcagtaggat ttggtaggga 11461 agaatgggat cttgcagatc ttgattctgc cgcacgaatt ttgaaggatt ctcctcggat 11521 tttagttcat tgtggagctt atactgcggt agataaggca gagtccgact cagagaacgc 11581 ttacaaaatc aattcgttat ctgtaaaaaa aatttcggaa gaatgtctaa aaagaaaaat 11641 ccatttaatt tatgtatcca ctgattttgt gtttgatgca aactcggaaa cgatcggtga 11701 tacgattcgt ttttggaaac cggattctac actttctcca aaaggaatct acggattatc 11761 aaaggcggaa ggggaaaagt ggattcgaaa tacatttgta gattctaaac aagcaaatat 11821 agttcgtacc agttgggtat attcctctca tggaaataat tttccaaaaa caattgtgaa 11881 acttttacaa gattccaatc gtcatgaatt aagagtgatc gaagatcaat tgggaagacc 11941 tacttgggct ggtaggcttg cggattttat aatattctta atttatggaa ttctaaaagg 12001 agaatcttat cctgagattc tacatttttc taactcagga gttgcgagct ggtacgattt 12061 tgcacttgcg gttcgggatt tttcacattc tttttcattg atagaaaatt tgaagccgat 12121 ttatccaatt cctacggaag gttatccaac acctgcacct aggcctagat attcaatttt 12181 agatttagaa gaaactcgaa aaatttttgg cgttgttccg cattggagag aggatttaac 12241 cctttgtctg aaagaacttg ccgaagtttc cggaaaaaaa gtatgaaaaa aattttagtt 12301 acgggtggag ccggttttat aggttccaat tttgtaaatc tcatcttaaa cgataccaaa 12361 gaatatcagg tagtcgtatt cgataagctg acttatgctg gaaatctgag aagcttggaa 12421 tcttggaaaa aagattctcg atttattttt gtaaaggcag atatcgccaa taaagaagag 12481 gtatcttcga tttttcaaga gcataaattt aattacattg cacactttgc ggcagaaagc 12541 cacgtagatc gttctatttc aggaccggaa gaattcatca aaacgaatgt gcttggtact 12601 ttttatcttt tggatgctgc tagactacaa tggaatggat cttatgaagg aaaaaaattt 12661 cttcatgtat ctacggacga agtatttgga acgttaggag atagcggata tttcacagag 12721 gaaactcctt atgcacctaa ttctccttat tcggcctcta aagccagttc ggatcatatc 12781 gtaagatctt actaccatac ttatcatatg ccggtagtga ctacaaattg ttccaataat 12841 tatggacctt atcattttcc cgaaaagttg attcctttga tgattttaaa ttgtttacaa 12901 ggaaaacctc tacccgttta cggagacgga aagaatatta gagattggtt atatgttaag 12961 gatcattgtg aggctctacg tgttgctttg ttccagggat tgtccgggga aacttacaac 13021 ataggaacta gaaacgaaaa aaagaatata gacatagtag attccatttg ttccattatg 13081 gacgagttgc atccttcggg ggctccacat tctaaattga ttcagtatgt aaaggacaga 13141 ccaggtcacg attttcgtta tgcaattgat ccttccaaga tcgaaaaaga attgggatgg 13201 aagcctaaat ttgcatttga atcggcttta aaagaaactg ttcggtggta tttagagaat 13261 gaatcttggt ggaaggaaat tctttccggt caatataaag aatattatga aaatcagtac 13321 gagaaacgtt agatgaaatc tagaaaagga attatactcg caggcggttc tggaacaaga 13381 ctttatccgg tcacatacgt agtttccaaa caacttttac cggtttatga taaaccgatg 13441 atctactacc cactaacaac gcttatgcta gcgggtatca aagaaatact tttgatttcc 13501 acacctcaag ctactcctat gtataaagaa ctgttaggag atggaaaaca atggggaatt 13561 tccatagaat atgcggtaca acccaatccg ggaggattgg cgcaagcgta ttggatcgga 13621 gaaaatttcg tcaacggaca tccgtctgtt ttgattcttg gagataatat ctatttcggt 13681 cataatcttg cttctctttt agaaaacgct tctaaaaaag agaacggttc tactgtgttc 13741 gcgtatccgg ttcatgatcc agaaaggtat ggagtggtag agtttgattc tgaaagacgt 13801 gcggtttcga tcgaagaaaa accttctaaa ccgaaatcta attatgcagt cactggatta 13861 tatttttatg atgaagaagt tgttaatata gctaaatcta ttaaaccttc tgcaagggga 13921 gaattggaga ttacagacgt aaataggatt tatttagaaa gaggaatttt aaacgttcaa 13981 gtgatgggac gagggtatgc ttggttggac actgggactc acgaatcact tttagaggca 14041 tctgtattta tagaaacgat tgaaaaaaga caaggactta aagttgcctg cccggaagaa 14101 attgcgttta gaaaaggttt tatagatgga tctcaattag aaaaattgat aagtcctctt 14161 aaaaaaacag gttatggaga atatcttgta aaagtactta atgaaaagat ttactaaatt 14221 tcatagaggc tttacatttt taaattgttc gtttcttaat tttactataa acatattatt 14281 ttcagattgt tattggatcg tgtaattagt gtttaccttt tgaatctagg atatttgata 14341 taatcttaat atttctcttt gtaataatgt attgctttag tagtatttaa gaatcatctt 14401 gctctaaatg acttgcattt aatatattca aaagattgaa tttttatgga attgttgaat 14461 cctactaaca cagtttgaat tttactaaaa attcatattg agataaaaag tctgtcttaa 14521 aatttgaaaa gaaaccaatc atagtcattt tgataatttc attattagag ttgttgaaaa 14581 attccatagc aacaattaac aaaacgcctc aatcgaccgt ttccatgaaa tagaaatcaa 14641 tggaaaatta atttttcaac aattctatta gaatagtagt tttcactaat tgtgtcgtat 14701 taaagtctca agttgtctaa gaattcatat tactcattct tatagaattg agtacccaca 14761 acgtgccatt taacgtaagt tcggtataat ctaattcgaa agcgattgag gcgaaggaac 14821 tcaagcagaa cgctctttca aacttatcgt cttactccct gaatgtcgat cttagagaag 14881 tattcgctga gttttccggg ttgagtttga actcagcaaa acgctttcct aaactcaaat 14941 ctcgctccca atggtcgtta gataggtcgt ttgacggatc gagttctata acaaattgaa 15001 atcatgaaaa gattttgttt ttaaatgcct cgatcaattt gttgattgga attgaaatcg 15061 cgcggtctag taatgcccga ctttattaca cagaatccat attattgaag tgtaagctta 15121 ttgaatcggg tattttatta tatagttctg aatagatatt ttaaaccacg gtttcaaaaa 15181 acagacttat tctaataaat gaaatattat aatattataa caattacata taattccaag 15241 aaatatattt ctgcattgga tcaatccatg caattgcctt ctaattggac ttggataatt 15301 tgggacaatg attccaagga tggcacacag gagcagctta aactactttc caaaaaaaat 15361 aaaagatcga tccattttag ttctaaaaat ttaggttttg cgggtggaaa caacgaggcg 15421 atcaaagtgg cacctaagtc ggattggact ttactaatca atccggattc tcgcttgagc 15481 gataatttct tttccgaatg cgagaggaca ctcgaatcta agggaaaaga gtattctatc 15541 atttcctttt taatgcttaa agataatcaa gaggaaaaaa agttaataga cggggccggg 15601 gatatttatc acgtttctgg ggctgcatgg agaagggggt ataaaagaat tctctctgaa 15661 gaatatctaa gagaatctga aatattttct gcatgtggtg gtgcgatggc aattcgaaca 15721 gaagtatatg aaagaatagg cggatttgat tctgattttt tctgttatat ggaagatgtg 15781 gatctaagct ttcgtgctag acttatggga gagagagtac tttttagtcc gaacattaag 15841 gtttatcatc acggatttgg atctaccgaa gaaaaaagta ctttttccct ttattatggt 15901 ctaagaaacg cgttagtcgt ttattggaaa aatatgcctc tgccttatgc tttacgttat 15961 atactccatc atatactttt ttttggagta agtatttgtt ttcatacagt ctttacgagc 16021 cctaaaatat taggagtacc ttttggcttt ttaagaatgt tgcctggaat tatccgtaaa 16081 agattagata ttcagaatat tcagggtaat aaatttagta aaactttaat gtggatgaac 16141 cgaggatggt ttaccccgtt tcgtaaaaaa tagtaatatg ccagagaagt tttctccatt 16201 agctgtcatt gttactttta atcctgatat aaatttaact tataaaaacg tacaaaatct 16261 aaatttaaat tcagttccag ttttgatcgt agataatcag tcaaagaatg tgtctgcgat 16321 tcgttctaaa attaaaaaac aaaattttct tatagagaat gaatcgaatc tgggtttggg 16381 gtttgcccta aatagaggaa ttgaatatgc ccagtcgaat ttatatacac acgtttggtt 16441 gtttgatcaa gatagctttt tagaaacttc ggcgatacga ttatttcttc aaaaaattag 16501 agaatatgaa attcaaaaat ttccaaatga gaaagttgct tcttatggtc ctaatatatt 16561 tgatacaatc aaaaaccgta atatttatgg aattctaaaa gacgaaaccg gaattttaaa 16621 tgcaaagttt ctaataactt ctggaagttt ttattcatta gaagttttaa aagaagtggg 16681 tttaatgtat caagatttct ttatagacta tttggattac gagtggtgct ttcgggccaa 16741 tgataaaggt tatgttcata aaattatttc cgatgtaaaa atgaaacatt ctattgggag 16801 tgattctagg agtatattcg ggatttttaa agttgcaatt cattcgcctt ttagatggta 16861 ttttcttttt agaaatggaa tttatatttg taaaatgccg catattccgt ttcgatttaa 16921 attagaagta gttttaaaaa caatctttcg atttttgatt ttgcctattt tttctgattc 16981 taaatatcaa acgtatcttc atattctttg cggaatttgt gatgggatta ccggaagaaa 17041 atcctctttt tataaacatc ttgtaggtga aactttttct acaacttaaa acaaatctaa 17101 gttcaaatac ttttttgtga atttttagaa aattgaaaat gaaatagaaa aactgcgtca 17161 gtcatttttg ttactattcg gacgcttggc atttgtatcc aaaattaaca atcaatttta 17221 taaagattaa aaagttctca aaaattatgc ctaatccgga ttttggtgtg agttcccaca 17281 ttttaaattt aactgtaaaa cccgcaaatt gtgtgagttc ccacatttta aatttaactg 17341 taaaacctgc aaattgtgtg agttcccaca tttttaaaat attaaactga taaaatttac 17401 ttgagggctg aattttggaa tttggaatta ccgtttcgat tgtattatat aaaccgaatg 17461 tatcaatttt aaaagaatcg cttttgtctc ttctgaactc aatcacatat caaatttcta 17521 atgcttcaaa atcgatttta tataaaatcg agatattgga taatacccca caatacggag 17581 aagaagtaaa aaatatagtg aacgatttag aaaaaaagtt ttcgtccaaa aatcgtgtca 17641 aatttgaata cttccatttt cccgaaaatc ttggatacgg agttgccaat aaccgttcta 17701 ttttaaaatc aaatatggaa tttcatttag ttctcaatcc agatattaaa atgattccgg 17761 aaacattgga tttatgtgtt cgttatttgg aagaacatcc aggctgcgac gcggtagttc 17821 cttcagtttg ggattgggag agtgattcta ataaaaaacg taatatgcaa tttttagtaa 17881 aatcttatcc cactgttttt gtattatttt tgagatcttt tgcaccggat attttaaaaa 17941 aggtatttcg aaagtattta gatcaatacg atctaaggga taaggattgg aatcaaattc 18001 aggaagatgt atctttaatc agcggttgtt ttatttttgc aagaacaaag tctttaaaac 18061 aaatcggagg atttgacgaa agattttttt tgtatttcga ggattttgat ctttctatgc 18121 gtttgaagag aaaggattac tttccaaaga ttcaaattta tcacaaaggt ggaaattcgt 18181 ctaaaaaagg ctttttacac gtaaggcttt ttgtcatttc tgcaatccgt ttttttatga 18241 aattcggttg gaaactaatt taa //