LOCUS NC_003552:5 19255 bp DNA linear BCT 03-OCT-2011 DEFINITION Methanosarcina acetivorans C2A, complete genome. ACCESSION NC_003552 SOURCE Methanosarcina acetivorans C2A, complete genome. COMMENT locus start: 1157294; locus end: 1176548 FEATURES Location/Qualifiers source 1..19255 /organism="Methanosarcina acetivorans C2A, complete genome." gene 0..2492 /gene="" /locus_tag="" /db_xref="1157294..1159786" CDS 0..2492 /gene="" /product="sensory transduction histidine kinase" /translation="LQEYSKINSWSQKGIQKGNMNAKVEQTPATNQNLVLSVDNNGTI IHSNEASEPILKEWGVSVGEKLPSSIVDLVQRVISRNSPEKTEVKVGNKLYLVVFSPL PEEQRVSISGFDISDQKEFEKGMVSETREKAERDTLVEELRKSEKKYRTLFDTIDEGF CVIEVLFDEADCPIDYRFLEINASFERQTGIKNAVGRRMREIAPEHEEHWFQIYGNVA LTGEPVRFENPAIALGHFYDVYAFRTGDPDHRRVGILFNDIAKRKRAEEMLRESAERQ AFLLQLSDALRPLFDPIEIQAVATRVLGEHLGIARVAYGEVTDDDTFIVFERNYVAPG VPLVTGRFRMADFGPSLLSALKEGRTIVVPDLASSTELSEAERSGYANLGIASLMGVP LVKGGRFVAELVVHHTAPRQWSPAEVALIEETAERTWAAVERAKAEEALKESEERFRT LSETSPIGVGVSSAESKIIYTNPAYDRILGYNPSELIGRNSTDVYWNPEERKSWCRTL KDKGVVRDFETKFKKKDGTPVWVSINTSPISFGGRKAAMGTIQDISERKQAEEALRES ELKFRTLSNTLEEKVKERTVELEKAYKFLQEIDIIRKQEIHHRIKNNLQVISSLLDLQ AEKFRGKKNIEDSKILEAFKESQDRVISMALIHEELHKSGEIDTLNFSAYIHELSGNL FLSYRLGNDGISLDMDIEEDIFFDMDTSVPLGMIVNELVSNSLKHAFSDRDKGEIRIK LHRKKNRESDIEDCCIAFILSVSDNGIGIPKDLEIEDIESLGLQLVTTLIDQLDGELE LKRDDGTEFIVRFSITERDNQANSPTQQFNEF" gene complement(2916..3365) /gene="fur" /locus_tag="fur" /db_xref="1160210..1160659" CDS complement(2916..3365) /gene="fur" /product="ferric uptake regulation protein" /translation="MSNLQDSDPLIIKALRGKGYKATPQRIAIGQFVLHNHAHPTAQR IYSEVKKVYPTVSLATIYKTVQILKEVGLIQEFNLEKDQARFDPNMEPHAHLVCLQCK SINDCTDPMISEIVDRMSNEVDFSAGEWNFNIFGICSNCRRKKSICD" gene 3606..5816 /gene="" /locus_tag="" /db_xref="1160900..1163110" CDS 3606..5816 /gene="" /product="catalase/peroxidase" /translation="MGGNVMTDDKMNSVTSGANKQETGRDMSNRDWWPNHLKLEILHQ HSSKSNPMGEDFNYAKEFKSLDLAAVKKDLAALMTDSQDWWPADFGHYGPLFIRMAWH SAGTYRAGDGRGGGGRGQQRFAPLNSWPDNVNLDKARRLLWPIKQKYGRKISWADLMI LTGNVAMETMGFKTFGFGGGREDVWEPDQDVYWGSEDTWLGDERYTGDRDLENPLAAV QMGLIYVNPEGPNGNPDPIAAAKDIREVFARMAMNDEETVALIAGGHAFGKTHGAGPA SHVGPEPEAASIEAQGLGWKSSFGTGKGDDTITGGLEVTWTNTPTKWSNNFFRILFGY EWELTKSPAGAYQWKPKGGAGAGTIPDAHDPSKRHAPSMMTTDLSLRFDPVYEKISRH FYENPGQLADSFARAWFKLTHRDMGPRARYLGPEVPAEELIWQDPIPAVNHELIDEKD IAFLKDRILASGLSISQLVSTAWVSASTFRGSDKRGGANGARIRLAPQKDWEVNQPAE LAKVLNTLEGIQSEFNSAASGGKKVSLADLIVLAGCAGVEQAAKNAGYDVTVPFLPGR MDALQEQTDVVSFALLEPIADGFRNYLKAQYPLPAEELLVDKAQLLTLTAPEMTVLVG GMRVLNTNFGHTQHGVFTQKPEALTNDFFVNLLDMGTEWKAVSDVKDIFEGCDRKTGE VKWTGTRVDLIFGSNSQLRALAEVYGSADAQEKFVQDFVAAWTKVMNLDRFDLA" gene 6151..7437 /gene="" /locus_tag="" /db_xref="1163445..1164731" CDS 6151..7437 /gene="" /product="hypothetical protein" /translation="MGKGNIAIDKSMIKTIVDGKIIIPLPKVLVGNRYYPMFSIFSPT QCDSCGSKLHVNSHHTRFIISRYGTISLNVTYWLCPTCKKHYHDQVIGVQGSANYSSE YYDTQINVRYDGRCSLHNSRRIGETYTEGVINVCGRAPCPTSLWLYEQKLAKLSKQEL LNQGVSFEETLYVDGNWIKNGWKKKLEEFIGTKLTKKEWKKMRYKSVYVVATKEKVIL DFEVTERLPTIEALMPLFIRIKNRFPEDKIKKIVSDEDKAIIGAVKMVFPEVTHSFCV FHQLKNVSKRYYEEFSSIEEIPDNDKITYNEISQLILSDTVISAVAHIQKIREFNSDL ELSEASHKAISYAEEIFSKNVSFLKKGFTPETDNTMEQIFSLICDIVDKARSFKTNNG LTNFCYNLFTFFNKRCFSTGKWKGFSPLMRARFQYG" gene 7875..8201 /gene="" /locus_tag="" /db_xref="1165169..1165495" CDS 7875..8201 /gene="" /product="hypothetical protein" /translation="MGISKVEELANCDIQRLTERFGKMGLRLKQAAHGLDFSEIEESG EAIKSIIWSSTFKENTNDPIKIAGYLEMLAESVHKSLFKHRLYFLRSPAPLLPKNSVI FGGWKC" gene 8398..9768 /gene="frhA" /locus_tag="frhA" /db_xref="1165692..1167062" CDS 8398..9768 /gene="frhA" /product="coenzyme F420 hydrogenase, subunit alpha" /translation="LTKVVEISPTTRHEGHSKLTLKVNDQGIVERGDWLSITPVRGIE KLAIGKTMEQVPKIASRVCGICPIPHTLASIEAMEASIGCEIPTDVKLLRVILHAANR LHSHALHNILILPDFYIPGTETKINPFSKEQPLRSVAVRIFRIREIAQTIIAVAGGEA IHPSNPRVGGMYRNVSPRAKQKMADLAKEGLVLAHEQMEFMLEVIRNMQNRGFTDVAG KEIPIPRNLGYHNQGVMATAPMYGSSSLDEKPMWDFARWKDTRPWDWYMGEVTIDLED PSYPIGGTTKVGTKANPRMEACNTVPTYDGQPVEVGPRARLATFKNFTEKGTFAQHIA RQLEYPNCFYTILKCLDNLDTSGKVLADHIPQGDGSMGWAANEAPRGTDVHIARVKDG RVLWYEMLVPTTWNLPTCSRALTGAPWQIAEMVVRAYDPCVACATHMIVTDEENRIVA KKLLQW" gene 9775..10254 /gene="frhD" /locus_tag="frhD" /db_xref="1167069..1167548" CDS 9775..10254 /gene="frhD" /product="hydrogenase maturation protease" /translation="MDSLYSEIVVAGCGTPLYADDGFGPAVVESLKGLELPENVTVVD AGLGGPHFVFTLLNPESTKTLIIVDIADFGGEPGELRWLAVDELPVGSYRDAHSWDLA EPLQYIKDDIRIRVLACQKKYVSTPEMVIGITDEVQRAIPDAVSEILKEIGMNYGTA" gene 10259..11047 /gene="frhG" /locus_tag="frhG" /db_xref="1167553..1168341" CDS 10259..11047 /gene="frhG" /product="coenzyme F420 hydrogenase, subunit gamma" /translation="VEATKEAKPVANKIKLGHVHFSGCTGCLVSVADIYQGLLKILDD YADLVYALTLVDVRHIPEMDVALVEGSVCIQDRESVEDIKETRKKSRIVVALGSCATY GNITRFCRGGQHNQPQHESFLPIGDLIDVDVYIPGCPPSPELIRNVTVMAYLFLEGNE EQKALAGRYLKPLMALAKRGTTGCFCDLMNDVINQGLCIGCGTCAASCPVRAITHEFG KPQGDLNLCVKCGSCYGACPRSFFNFDVIPEFESISELIADALR" gene 11058..11933 /gene="frhB" /locus_tag="frhB" /db_xref="1168352..1169227" CDS 11058..11933 /gene="frhB" /product="coenzyme F420-reducing hydrogenase beta subunit" /translation="MVSDPYLGKYTTCISARSTDREILKKAQDGGIATTLMVYALEEG IIDGVIVAGEGDLPWKPRPFVAMSRKDILKAQKAKYNISPQISWIKEATRSFGLDKVG VTGVCCQIQAVRKAQLYPINMRDVPGKIAFVVGLFCMENFLYDSIQAIVEDHTNQSLS SVKKMRIGKGKFQVYTERGNVATAPLQATHKYGQPGCYVCLDYVSNLGDISTGSVGSP DGWSTVFVRTRVGNDIWSKAVDAGLFETKPIEEVKPGLELVMKLAKIKLDGNRKTLEE RRNFGVNKALRDPYA" gene complement(12191..13591) /gene="" /locus_tag="" /db_xref="1169485..1170885" CDS complement(12191..13591) /gene="" /product="hypothetical protein" /translation="MKGFKVDYIKEPKLLFNSGGTSLNPCIGLTKYGPRFSGSKNNDF REFKVGIIGSSKSIALTKELFETLQYKILPLGEIKPWKIPFPGLNSNSKLKFRFVFNP EWESIIEPTDLDKLQAANSSSEAALNLIKRKLKLIYEKETPPDIILISFPQEFYTICE CSETDKPLIKVGIDDFRNRIKLLAMQQKIPSQIVRPETLLLDGTQERCIVAWNLVVGM LYKCQKGHPWKLTHLEENTCYVGISFFNEKGKETRRASLAQIFLDTGESFVLRGDSFN WTNMKHPKSPHLSKDDAYNLMNYVLEHYRSIRRQNPNRVVVHKSSNFWNDELEGFREA TKNVPQKDFITILESSLKLFTQGRYPILRGTLLSLEDDTSGFLFSTGFVPSLNTYPGF SIPRALEIRPFNLDTSLVQVCKEILSFTKLDWNNTFVYSRMPVTISVSRKVGQVMSET EAQKFSELDSHYYFYM" gene complement(13593..14990) /gene="" /locus_tag="" /db_xref="1170887..1172284" CDS complement(13593..14990) /gene="" /product="hypothetical protein" /translation="MPFINLEGEREATTQNSKEYGKKIIEFLNLQGYHLEHDSNIEGI FSDKVFRNPKLDGYKRTVVEVKETKLSLSDTDFLKEFAKYFMSSLKEEFNLFIFVREV ANINKWKKIFDLSIQSEEELRHFYDKIKRVTELQDSNYGSFIKFINSTKVYQASYVKL FQKIEQIREDNVYDSGADYLEETENLVFQPEKLDSNCYLVKSFPESICLAELKSQVDL NSYWGNNSSKFHVPFKGILYSIREIPENLLSDYCEINSYRKINFCDIGLESTDKNSLI SQLIRTQIIQKASEQGFRLFGKSLYKPHTDFDCAISKIKVENEKLRYLSRIYFKEDGS INFIVHRALKFRTMVLNGHFFVLFDNYRLFSTDGKNIITGEHAKRLNYKFPPTKAFND PEKSKMYFLLKAIGLQISNSNILDFNQFNYKNQFTFERMIFEMPCKVESGEIFDENFD YEDNYYPKLTDYFEE" gene 15691..15960 /gene="" /locus_tag="" /db_xref="1172985..1173254" CDS 15691..15960 /gene="" /product="hypothetical protein" /translation="MSFKVLIHPKVFEKVPVDRRDQIKDALQELKDPLPGGNKKEVKG SHKTVYRLRIGDFRILYEIDFERSEVLVFNIITAEQAHKKYNRFK" gene 16579..16932 /gene="" /locus_tag="" /db_xref="1173873..1174226" CDS 16579..16932 /gene="" /product="Pin protein" /translation="LGRMKFFVDTSIFVDCLRKEVIPSSKSFLERIGDEYSGYTSSIT VAELSVGAHLSRSQDALEKTLELLNIVEVIDLDSRIAIDAGKIYADLIRSGKRIELND CLIAATALSLGINRE" gene 17157..17537 /gene="" /locus_tag="" /db_xref="1174451..1174831" CDS 17157..17537 /gene="" /product="hypothetical protein" /translation="LLRKVFSPKALNVQLYSFFNIFFGFFKGFTLRSHIEFRTSCNKK VIFFCYSYEKLSHGLLQVWFSHVFLQIFVAILFYIGVETVQSGSVLSLQNLLYTINFR EIETQFIFVCRFYHKICAYSWLSF" gene 18103..19254 /gene="" /locus_tag="" /db_xref="1175397..1176548" CDS 18103..19254 /gene="" /product="hypothetical protein" /translation="MSFPPYKSGYAPKIELKAKECIDAVLRPLNDHVTIKINGSLTSE DVFRTVVSMAVNRNSVHSVSTQYQDVACETSLRYHLKKLDMDELIKSNEKILLQELIE TLKTGKSYEFAVDYTNDPYYGKKDSSNEKYVIGGQAKKSTNSFYSYVSLYIINKTERF TLSVLPVEKKKTKVEYLSHFIDLIKRLDFKIKILCLDREFCTIDVFKFLQSKQIPHIV PVIKKGERMKKLLKGNKARNEQYVMGNSKKNILLDIVIDVKYLKGKRGKKGRKNLGFV VFGVKWSPRKVSTVYRRRFAIESSYRMRNVVKPKTSSKNASIRYFYALISFLLKNVWL FLQKKHFTIVKRGPQVIDEDKFRFRMFVVLIEEWLKRKLRVRLMVECLR" ORIGIN 1 ttgcaggaat atagtaaaat aaactcatgg tcacaaaagg gaatccaaaa agggaatatg 61 aacgctaaag tggaacaaac cccagcaacg aatcaaaatc ttgttctcag tgtagataat 121 aatggtacta ttattcactc aaatgaagcg agtgagccta tattaaaaga atggggtgta 181 agtgtaggag aaaaactacc ttcgagtatc gtagatcttg tacaaagggt aatctcccga 241 aatagccctg agaaaactga agttaaagtg ggaaataagc tatatttggt tgttttttct 301 cccttacctg aagaacaacg cgtaagtatc tctggattcg atataagtga ccagaaagaa 361 ttcgaaaagg gtatggtaag tgaaactcga gagaaagcag aacgggatac cttggtggaa 421 gaattaagga agagcgaaaa gaagtaccgc actctcttcg acacgattga cgaaggcttc 481 tgtgtgatcg aagtgttgtt tgatgaagca gactgcccta ttgactaccg ctttctggaa 541 atcaacgcct ctttcgagag gcagacaggc atcaagaacg ctgttgggcg acggatgcga 601 gagattgccc ccgagcacga agagcattgg tttcagatct acgggaacgt cgccctaacg 661 ggcgagcccg tacgcttcga gaatccggct attgctctcg gtcacttcta cgacgtctac 721 gcctttcgca ccggcgatcc cgatcaccgg cgggtaggta tcctcttcaa cgacatcgcc 781 aagcgcaagc gggcagagga gatgctgcgg gagagcgcgg agaggcaggc gttcctgctg 841 cagctctccg acgccctgcg gccgctcttc gatcctatcg agatccaggc ggtggcaacc 901 cgcgtcctcg gcgagcacct gggcatcgcc cgcgtggcct acggggaggt cacggatgat 961 gatacgttca tcgtcttcga acgcaactac gtcgcgcctg gcgtcccgtt ggtcaccggt 1021 aggttccgga tggccgactt tggtccgagc ctcctctctg cgctaaaaga ggggcgcacc 1081 atcgtcgtgc cggacctcgc atcctcgacc gaactttcgg aggctgaacg gtcgggatac 1141 gcgaatcttg gcattgcctc cctgatgggg gtgccgctgg tcaagggcgg ccggtttgtg 1201 gcggagctcg tcgtccatca tactgcccca cgacagtggt ctccagcgga ggtagcactc 1261 atcgaggaga cggctgagcg tacttgggcg gcggtcgaac gggcaaaagc cgaagaagct 1321 ttgaaagaga gtgaagagcg ttttagaaca cttagtgaaa catccccaat tggggtaggt 1381 gtgagctcag cagagagcaa aattatttac accaatcctg catatgatcg gattttaggt 1441 tataatccta gcgagcttat cggtaggaac tccacggatg tctattggaa ccccgaagag 1501 agaaagtcat ggtgtcgtac tttgaaagat aagggagtag tccgggattt tgagacaaag 1561 ttcaagaaaa aggatggtac gccagtttgg gtttccataa atacttcacc tatttccttt 1621 gggggcagga aagcagcgat gggtacgatt caggatatca gcgagcgcaa gcaggccgag 1681 gaggcgctac gcgaatcaga actaaaattc cgtaccttat caaacacttt agaagagaaa 1741 gttaaagaac gtacagttga gcttgagaaa gcttataagt ttttgcaaga aatcgatatt 1801 attcgcaaac aggaaattca ccatcgcatt aagaacaatc ttcaggttat ttcttccctt 1861 ctcgaccttc aggctgaaaa gtttagaggc aagaagaata ttgaagattc aaaaattctg 1921 gaagctttca aagaaagtca agaccgtgtc atttctatgg ctcttatcca tgaggaatta 1981 cacaaaagtg gagaaatcga tactcttaac ttttctgcat atatacacga actttctggt 2041 aatttatttc tctcctatag gcttggaaat gatggcataa gcctggatat ggatatagaa 2101 gaagacattt tctttgatat ggatacatct gttccactag gtatgatcgt taatgaactt 2161 gtctccaatt ctctaaaaca tgcattttct gacagggata aaggagaaat tagaattaag 2221 ctccacagaa agaaaaatag agaatccgat atagaagact gctgtatcgc tttcattctg 2281 tctgtttcag acaatggtat aggtattcca aaagatcttg aaatcgaaga tattgaaagt 2341 ctggggcttc agttggtaac tactctcata gaccagttag atggggaact tgagctgaaa 2401 agggatgatg ggactgagtt cattgttagg ttttctatca cagaaaggga taatcaggca 2461 aattctccaa cacaacagtt taatgagttt tgaggtacct attaaatatt ttttaaattt 2521 aatataaatt ccagctgcac actttcgtag gaagattgaa acactttaac ctaatttaga 2581 aaataagaag taaatatatt tataactaaa ttcaggtctt caaataccct aattattttt 2641 tgaagtaaaa ttcttactct gtcaagtcta cggaagctaa agaatttttc cagctacggt 2701 taaacgtaaa aatgcccatc ctccgccaac cggacagaac ttcaaatact ttttggtaac 2761 tgaataattg cccaacaatt ttttcttttc tatttatcac ataaactttt tttccattag 2821 gagttactgt atctccgtaa gaaaatattc ctacatgtat cgtggcaata acagtaagtt 2881 attgtgtcta taattgaaac aatgttataa acagagtcag tcacatatac tctttttccg 2941 tctacagttg ctgcaaatgc caaatatgtt aaaattccat tctccagcag aaaaatctac 3001 ttcatttgac attcgatcca caatttcaga aatcatgggg tctgtgcagt cattgatgct 3061 tttgcattgg aggcaaacca gatgcgcgtg tggctccata ttgggatcaa atctggcctg 3121 atctttctct aaattgaatt cctggatcaa acctacctct ttcaagattt gaacagtttt 3181 atatattgtt gcaagactga ctgttggata gaccttcttg acctcgctat aaattctctg 3241 agccgttgga tgggcatgat tgtggagaac aaattgaccg atcgctattc tctggggtgt 3301 agccttgtat ccttttccgc gcagagcttt gattatgagt gggtctgagt cctgaaggtt 3361 actcatagtt tattattaag taataatcaa tcttaaatag atttgtgtta tatagttgaa 3421 tatcgaactg gaatgagttc tttggggaag taaaccatta gactatcaaa acagcatgta 3481 agaattttca agctcttgga aagtagacct aaattaatca ctctggcaat cggcactcaa 3541 atctcccaag aggagacaag attgaagaga ttgcatacta gagatttggt cttgaatttt 3601 tagtcaatgg gaggtaacgt tatgactgac gacaaaatga attctgtaac gagcggagca 3661 aacaaacaag aaaccggtag agacatgtcg aaccgcgact ggtggccgaa ccatttgaag 3721 cttgagatcc tgcaccagca ttcctccaag tccaacccga tgggcgagga cttcaattac 3781 gcgaaggagt tcaagagcct agatctggcg gctgtgaaaa aagatcttgc ggcgctgatg 3841 accgattcgc aggactggtg gccggcggat tttggccatt atggcccttt gtttattcgc 3901 atggcatggc acagcgcagg cacttatcgc gccggtgacg gccgcggcgg cggcggtaga 3961 ggccagcaac gcttcgcgcc gctcaacagt tggccggaca atgtcaacct ggacaaagcg 4021 cgtcgtctgc tctggccgat caagcagaag tatggccgga aaatttcatg ggccgacctt 4081 atgattctta cgggcaacgt cgcaatggaa actatgggat tcaaaacgtt tggtttcggg 4141 ggcggtcgcg aggacgtctg ggagccggac caggacgtct attggggctc tgaggacacg 4201 tggctgggtg atgaacgcta caccggcgac cgggacctcg aaaatccgct cgctgccgtg 4261 cagatggggc tgatctatgt caatccggaa ggcccgaacg gcaatccgga tccgatagcg 4321 gcggccaaag atatccgcga ggttttcgct cgcatggcca tgaacgacga agagaccgtt 4381 gcgctcatcg ctggcggtca cgccttcgga aaaacccacg gtgccggccc tgcgtcccat 4441 gtcgggcctg agccagaagc ggccagtatc gaggcgcaag gtctcggttg gaagagcagc 4501 ttcggcactg gcaaaggcga tgacacgatc accggcggcc tggaggtcac ctggaccaac 4561 acaccaacga agtggagtaa caacttcttc aggatcctgt tcggctacga gtgggaattg 4621 acgaagagcc cggccggtgc atatcagtgg aaacctaaag gtggcgcagg tgccggcacg 4681 attccggacg cccacgaccc ttccaagcgt cacgcgccaa gcatgatgac cactgacctt 4741 tccttgaggt tcgaccccgt ctacgaaaag atttcaaggc acttctacga gaacccgggt 4801 caattagcgg actcattcgc ccgcgcatgg ttcaagctga ctcaccgcga catgggtccg 4861 cgcgcccgct atctcggtcc ggaggttcct gccgaagagc tcatctggca agacccaatc 4921 cccgcggtca atcacgagtt gatcgatgag aaggatattg ccttcctcaa ggacaggatc 4981 cttgcctcag ggctgtcgat ctcgcaactg gtttcgaccg cctgggtgtc ggcgtccacc 5041 ttccgtggct ccgacaaacg tggcggtgca aacggcgcac gaattcgcct cgcgccgcag 5101 aaggattggg aagtcaacca accagccgaa ctggcgaaag tgctgaacac tctcgagggt 5161 atccagagcg agttcaacag cgcggcctcc ggtggcaaga aggtatcgct tgctgacctg 5221 atagttctgg ctggttgtgc aggcgtcgag caggctgcga agaatgctgg ttacgatgtg 5281 actgttccct tcttgccggg gcgcatggat gccttgcagg agcagaccga tgttgtctcc 5341 ttcgctttac tcgaaccgat cgcggatggc ttccgcaact atctcaaggc ccagtacccc 5401 ttaccggccg aggagttgct ggttgacaag gcgcaattgc tgactctgac cgcaccagag 5461 atgacggtgc ttgttggcgg catgcgcgtg ctgaacacca acttcggaca tacccagcac 5521 ggcgttttta cccagaagcc ggaagcgcta accaacgact tcttcgtgaa cctgctcgac 5581 atgggtacgg aatggaaggc ggtatcggac gtcaaggaca tatttgaagg gtgcgatcgc 5641 aagactggcg aagtcaagtg gaccggcacg cgtgtcgatc tcatcttcgg ttctaactcc 5701 cagctccggg ctcttgccga ggtctacgga agcgcggatg cgcaggagaa gtttgttcag 5761 gacttcgtgg cggcctggac caaggtaatg aaccttgatc gcttcgacct agcctgatcg 5821 agtagaaatg tcttcaaggg cttgaagatc ttcaaaacaa aagactttac ccaggctgga 5881 gaaaggtatc ggtcgcttga caagataggg caggaacata tgattggtaa acttgtgggc 5941 gacctgagcc acgtcaccat tccagctatt cagagacgtg aaaacgaaaa ctcacggcag 6001 gctgatgaga ctttgcagca tctgtagatc cagaaggagt tcgaggatat attgaaataa 6061 gagacttttt attattttct ggtttttcgt tttccctcta tatcgtgcaa aacaataaaa 6121 ttttaattat attgatatat tttttctatt tatgggaaaa ggaaacattg caatagataa 6181 atcaatgata aaaacgatag ttgacggcaa aataataatt cctttgccaa aagttttggt 6241 tggaaatcga tactatccca tgttctctat attctcccct actcagtgtg atagttgtgg 6301 aagtaaatta catgttaact ctcatcacac tcgttttatt atatcacgtt acggcactat 6361 atctctcaat gttacatact ggctttgtcc cacttgtaag aaacattatc atgatcaggt 6421 tattggtgtt cagggttctg caaattacag ttctgaatat tatgatacac aaataaatgt 6481 cagatacgat ggacgatgca gtctgcacaa ttctcggcga attggggaaa catatacaga 6541 aggagtaata aatgtctgtg gaagagctcc ttgtcccact tcattgtggt tatatgaaca 6601 gaaactagca aaactttcaa agcaagaact tttgaaccaa ggagttagct ttgaagaaac 6661 attgtatgtt gatgggaatt ggatcaagaa tggatggaaa aaaaagcttg aagaatttat 6721 tggaacgaaa ctcacaaaga aagaatggaa aaaaatgcga tataaatctg tttacgttgt 6781 tgctaccaaa gagaaggtca ttttagattt tgaagtaact gagaggttac caacaattga 6841 ggctctgatg cctcttttta tacgaataaa gaaccgattt cctgaagata aaatcaaaaa 6901 gattgtttct gatgaggata aagcgatcat tggagccgta aaaatggtct ttcctgaagt 6961 gactcattct ttttgtgtgt ttcatcaatt aaaaaacgtt agtaagaggt attatgagga 7021 attcagttct attgaagaga ttccagataa cgataagatt acctacaatg agatatctca 7081 attgatactt tctgatacgg ttatcagtgc tgttgcgcat attcagaaga tacgagaatt 7141 taactctgat cttgaacttt ctgaagcgtc tcataaagcg atttcttatg ccgaagagat 7201 tttcagcaag aatgtgagct tcttgaaaaa aggttttaca cctgagacag ataatacaat 7261 ggaacagata ttttctttga tatgtgatat agtagacaaa gcgaggtcat tcaaaaccaa 7321 taatggacta actaattttt gttacaatct atttactttt ttcaacaaac ggtgtttcag 7381 cactggaaaa tggaaaggtt tctcaccttt aatgagagca agattccaat atggataatg 7441 ctagaattgg agaataatta gttcttaaac ttgatggctt atagctgtag ctgtcggaaa 7501 ttcccacaaa aatagttcca caatttggaa aattttggtg gatgcttgtg tgaatgaatc 7561 aacattttta aatgagtgaa ttgatttgct caaattggga taaaattttg tggttgtctt 7621 gagattgaag aaaaaccaga aaaaattaaa aagactctga aataaagaag gctatcctcg 7681 aattctctat tttttatcgc ggaattgtcc attgattgca ctcactttgg cttctgggtt 7741 gcctgattgt tatgctagat tactatttcc gcaagttaac aatctctatg aatcaacgac 7801 cccactcttg ttttcccgtc agatgtctca taaatccctg gaattgatca aaaaactaca 7861 gaggcacttt aactcatggg aataagcaaa gttgaagagc ttgcgaactg cgatatccag 7921 aggcttactg aaaggttcgg gaaaatgggt ctccggttga aacaggcggc acatggtctg 7981 gatttcagtg aaattgagga aagtggggaa gctataaaat caattatctg gagcagtact 8041 tttaaggaga acacaaacga tccaataaaa atagcggggt atttagagat gcttgctgag 8101 agcgtgcaca aatctctctt taagcatcga ttatattttt taagatctcc ggcccccctc 8161 cttcccaaaa attcggtaat tttcggaggc tggaaatgtt aaggaaggta tgcactccat 8221 ctggagtgaa tcattagctg aagaacttga tctgagtcag agtatccagt atgtattatt 8281 atagaaccta atattataga atgtaatatt atatcactat aatcgattaa tatcactata 8341 atcgtaactc tggaaggggg aaatccaaga gtacagaatc gaaagcgagg ggatgccatt 8401 gacgaaagtt gtagagatct ctccaaccac tagacatgaa ggccactcca agctcaccct 8461 gaaggtgaat gatcagggta tcgtcgagcg aggagactgg ctctctatca ccccggtaag 8521 gggtattgag aaactcgcca taggtaagac gatggaacag gttccgaaga ttgcatctcg 8581 ggtctgtggt atctgtccca tcccccacac cctggcaagc atcgaggcta tggaggcctc 8641 tatcggctgc gagatcccca cggacgtaaa gctcctgcgg gtcattctcc atgccgcgaa 8701 ccgcctccac agccacgccc tgcacaatat cctgatcctt ccggactttt acatccccgg 8761 gacggagacg aagatcaacc cgttttccaa ggagcagcct ttaaggagcg ttgcggtgag 8821 aattttccgc attcgtgaga ttgcacagac cattatagcc gtcgcaggcg gcgaggcgat 8881 ccacccctcc aacccgaggg tcggcgggat gtaccgcaac gtgagccccc gggcaaagca 8941 gaagatggcc gacctggcaa aggaaggcct cgtccttgcc cacgaacaga tggagttcat 9001 gctcgaggtc atcaggaaca tgcagaatag ggggttcacc gatgtcgcgg gcaaggagat 9061 cccgattccc agaaatctag ggtaccacaa ccagggggtt atggccacag cccctatgta 9121 cggctcatcc agtctggacg agaagcccat gtgggacttt gcccggtgga aagatacccg 9181 accatgggat tggtacatgg gtgaggttac catcgatctt gaggatccga gctacccgat 9241 aggcggcacc acgaaggtcg gcactaaagc caatccccgg atggaggcct gcaacaccgt 9301 tccgacctac gacggccagc cggttgaggt cggtccgaga gcaagactcg ctactttcaa 9361 gaacttcacc gagaagggca ccttcgccca gcacatcgcc aggcagctgg agtaccccaa 9421 ctgcttctac accatcctca agtgccttga caatctggat acttcgggaa aggtcctcgc 9481 cgaccacatc cctcagggag acgggtccat gggctgggct gcaaacgagg ccccgcgcgg 9541 gaccgatgtc cacatcgcac gggtgaagga cgggcgggtg ctgtggtatg agatgcttgt 9601 acccacaacc tggaacctcc cgacctgtag ccgcgctctg acgggagcgc cctggcagat 9661 cgccgagatg gttgtccggg cctatgaccc gtgcgttgcg tgcgcaaccc acatgatcgt 9721 aacggacgag gagaacagga tagttgccaa gaagctcctc cagtggtgaa gggaaatgga 9781 ttcgctgtac tccgagatcg tggtggcagg ctgtggcacc ccgctctatg cggacgatgg 9841 gttcggaccc gcagtcgtgg agagtctcaa gggacttgag cttcccgaga acgtcacggt 9901 cgttgacgca gggctcggag gtccccattt tgtctttacc ctcctcaatc ccgagtccac 9961 gaagactctt atcatcgtgg acattgcgga cttcggaggg gaacccggcg aactcaggtg 10021 gcttgccgtt gacgagctcc ccgtcgggag ctaccgggac gcccactcct gggatctggc 10081 cgagccactc cagtacatta aggatgatat ccggatccgg gtccttgcat gccagaagaa 10141 gtacgtttct acccctgaga tggtcatcgg gattacagat gaggtgcaga gagccattcc 10201 ggacgctgta tccgagatac tgaaggaaat cgggatgaat tatggaactg cttaagaagg 10261 tggaagctac aaaggaggcg aaaccagtgg caaacaagat caagctcggg catgtacact 10321 ttagcggctg taccggctgc cttgtgtccg tggccgatat ctaccaggga cttctcaaaa 10381 tcctggacga ctacgccgac ctcgtctacg ccctcacgct tgtcgacgtc cgacatatcc 10441 cggagatgga cgtggcgctt gtcgaggggt cggtctgcat ccaggaccgt gaatcggtgg 10501 aggatatcaa ggagacgcgg aagaagtcca ggatcgtggt ggctctcggc tcctgtgcga 10561 cctacgggaa catcacccgg ttctgccgcg gagggcagca caaccagccc cagcatgagt 10621 ccttcctccc tatcggggat ctcatcgacg tggatgtcta catccccgga tgccctccaa 10681 gcccggagct aataaggaac gtcactgtca tggcgtacct gttcctggaa gggaatgagg 10741 aacagaaggc ccttgcaggc aggtacttaa agcccctcat ggcccttgcg aagcgtggca 10801 caaccggatg cttctgcgac ctgatgaacg acgtgatcaa ccagggcctc tgcataggct 10861 gtggcacctg cgctgcatcc tgtcccgtgc gggcgatcac ccacgagttc gggaagccgc 10921 agggtgacct taacctctgc gtcaagtgcg ggtcctgcta tggcgcctgc ccgaggtcgt 10981 ttttcaactt cgacgtgatt cctgaattcg agagcatcag cgagctaatc gcagacgcgc 11041 ttaggtgagg tgagaaagat ggtttcggat ccgtatctcg gaaaatacac aacctgcatc 11101 tcggcacgga gcacggacag ggagatcctg aagaaggcac aggacggcgg catcgccacc 11161 actctcatgg tctatgccct cgaagagggg ataatcgacg gggtcattgt ggcaggtgag 11221 ggcgacctgc cctggaagcc caggccattc gtcgcgatga gccgcaagga tatcctcaag 11281 gcacagaagg ctaagtacaa catcagcccc cagatctcct ggatcaaaga ggcgacccgg 11341 tccttcggcc tcgacaaggt cggggtcacc ggcgtctgct gccagataca ggctgtcagg 11401 aaggcccagc tatatcctat caacatgcgg gatgtccccg gcaagatcgc gttcgtagta 11461 gggctcttct gcatggagaa cttcctgtac gattccatac aggccattgt cgaggaccac 11521 acgaaccaga gcctcagctc cgtaaagaag atgaggatcg ggaagggtaa gttccaggtc 11581 tacaccgagc gtgggaacgt agccaccgcg ccgctccaag cgacccataa atacgggcag 11641 cccggctgct acgtctgcct cgattatgtc tcaaacctcg gcgacatctc aaccggctcg 11701 gtcggaagcc ccgacggctg gtccacggtc ttcgtccgca ccagggtggg gaatgacatc 11761 tggtccaaag cagtcgacgc aggccttttt gagactaagc ccatcgagga ggtcaaaccc 11821 ggcctggagc tcgtcatgaa gcttgcgaag ataaagctcg acgggaaccg gaagacactc 11881 gaggaacgca ggaatttcgg tgttaataag gcgttaaggg atccttacgc ctgaatttat 11941 ctttttttcg tcatagaaat tattcggcgt tattgcacca aaaaaagaga tgggaggttc 12001 tcatcctcaa attctgattt ccaactctgt aacttatcta tcgagctata gcggctgaga 12061 gatgccgaat ctatgggagt ggagtctctt caaatattgt acttgggaat taaagaatag 12121 aatttcagtg tcaataattc ctatgcaaca caaactcata atcataccta aaaagtacta 12181 ggaaccattt ttcacatata aaaataataa tgtgaatcaa gttctgagaa tttttgtgcc 12241 tcagtttcac tcattacttg accaactttc cttgagactg atatagtaac aggcattctt 12301 gagtacacaa aagtattgtt ccagtctaat ttagtaaatg ataatatttc cttgcatact 12361 tgaaccaatg aagtgtctaa attgaaaggc cttatctcca aggctcttgg aattgaaaaa 12421 ccaggataag tgtttaaaga agggacaaag cctgttgaaa ataagaaacc cgatgtatca 12481 tcttcaagtg acagtaatgt tcctctcaaa ataggatatc ggccttgggt gaatagtttt 12541 aaacttgact ctagtatcgt aataaaatcc ttttgaggaa cattttttgt ggcttcacga 12601 aagccttcta actcatcatt ccagaagtta gaacttttat gaactacgac cctgtttgga 12661 ttttgtcgtc ttattgatct gtaatgttcc aaaacgtaat tcattaaatt gtaggcgtca 12721 tctttagata aatggggact tttaggatgc ttcatattag tccaattaaa agagtctcct 12781 cttaatacaa aactttctcc tgtatctaaa aaaatttgag ctaagctagc ccttctagtt 12841 tctttaccct tctcattaaa aaaagaaata ccaacatagc atgtgttttc ctctaagtgc 12901 gtaagtttcc aaggatgtcc tttttggcat ttgtataaca taccaactac aagattccaa 12961 gcaactatgc atctctcttg tgttccgtct aacaaaagtg tttctggtct aacgatttga 13021 gatgggatct tttgttgcat ggccagtagc ttaattctat tgcgaaaatc atcaatccca 13081 actttaatca aaggtttatc tgtttctgag cattcacaaa tagtataaaa ttcttgtgga 13141 aaactgatta aaattatgtc aggaggagtt tctttttcat aaattagttt taattttctt 13201 tttattaggt tcaaagccgc ttctgaagaa gaatttgctg cttgtagttt atctaaatca 13261 gtaggctcta ttattgattc ccattctgga ttaaaaacaa acctgaattt taactttgaa 13321 ttcgaattca aacctggaaa tggtattttc caaggtttta tttctcctaa aggtaatatt 13381 ttatactgaa gggtttcaaa taactccttt gtcagagcaa tagatttgga agaaccaata 13441 attcctactt taaattctct aaaatcatta tttttactac ctgagaagcg gggaccatat 13501 tttgttagcc caatgcacgg atttaaagat gttcctccac tattaaacaa cagctttggc 13561 tctttaatgt aatctacttt aaaccctttc atttcattcc tcgaaataat cagtcaactt 13621 tggataataa ttgtcttcgt agtcaaaatt ctcatcgaat atttctccac tctccacttt 13681 gcagggcatc tcaaatatca ttctctcaaa agtaaattga tttttataat taaactggtt 13741 aaaatcaagt atatttgaat tggaaatctg taaacctata gccttcaata aaaagtacat 13801 tttacttttc tcaggatcat taaacgcttt tgtgggaggg aacttataat tcagcctttt 13861 tgcgtgttca ccagttatta tatttttccc gtcagtacta aataatctat agttgtcaaa 13921 tagtacaaaa aaatgtccat taagtaccat cgtcctgaat ttcaaagccc tatgaacaat 13981 gaaatttatg gagccgtctt ctttgaaata aattcttgat aagtacctta acttttcatt 14041 ttcaacttta atttttgata ttgcacaatc aaagtctgta tgtggtttat acaaactttt 14101 tccaaagaga cgaaaacctt gctctgaagc tttttgaatt atttgagttc gaatcagttg 14161 ggatatcaag ctattcttat cggtagactc aagccctatg tcacaaaagt taattttccg 14221 gtaagagtta atttcacaat agtctgacaa caaattttcg ggaatttctc taattgaata 14281 taaaattcct ttgaatggaa catgaaattt cgaggaatta tttccccaat atgagtttaa 14341 atcaacttga gacttcagct ctgctaaaca aatagattct gggaatgatt tcactaaata 14401 gcagttacta tccaacttct cgggttgaaa gactaaattc tcagtttctt ctaagtagtc 14461 tgctccagaa tcataaacat tatcttctct aatttgctcg attttttgga ataatttaac 14521 ataactcgct tgatagactt ttgtggaatt gataaatttt ataaaggatc cataatttga 14581 atcttgtaat tctgtgaccc ttttaatctt atcgtaaaaa tggcgcagtt cttcctcaga 14641 ttgaattgac aaatcgaata tttttttcca tttgtttata ttagctacct ctctaacaaa 14701 tataaacaga ttgaattctt cttttaaact gctcatgaaa tatttagcga attcctttag 14761 aaaatctgta tcgcttaaac tcagttttgt ctctttgact tctacaactg ttcttttata 14821 tccatcaagt tttggatttc taaatacttt atctgagaaa ataccctcaa tatttgagtc 14881 gtgttccaag tgataacctt gcaagtttag gaattcgatt attttcttcc catattcttt 14941 actattttgt gttgtagctt cgcgctctcc ttccaaattt ataaacggca ttctgctccc 15001 ttcataactt tttaggagaa atcattgagt taattaggta atataattat aatcatgaaa 15061 tgtaagcact tcactaacat caaaaattca taatattata aagacaactc taatatttat 15121 aatggtagta attgtattcg aaaacatttt tgctaacaaa aagtaatgtt ttgctatcgt 15181 aggcgcagcg tcaagatgta aaaggtaaag ttataatcat aaggttcctt ggtgcttatt 15241 aacctaatta tgaggataaa tactgctaat attgtaccat ctgtaacgcg ttttatgaat 15301 ctactgattc tacttcgctt tttttgcccg tttccgcccg atatcttctc ctttcgcgag 15361 catgcgggcg tggagggaag ttttaagatg agtctaaaaa agcttatttt aagcagattg 15421 ttaaagctga gaaagtaaaa gcatgagtaa ctttatcagt ttttcaattg tcataatata 15481 aatgctataa ttgctatagt aactattatg tcagaaacta caactataca gatatctaaa 15541 gacacccgtg atgagttaaa agccattggg aaaatggggg atgactacaa tacagttata 15601 cgaaaattga tccatgaaca caactgcaat aaacttatag aagaaggcga taggctcata 15661 agagaacatc gtgatgagtt cgtgagcatc gatgagcttt aaagttctga tccaccctaa 15721 ggtcttcgaa aaggttcctg tagatcgtag ggatcaaata aaagatgccc ttcaagaact 15781 aaaagacccc ttgccagggg gaaacaaaaa agaagtaaaa ggaagtcaca aaactgtcta 15841 tcggcttcgt ataggcgatt ttcgtatttt atacgaaatt gattttgaac gaagcgaggt 15901 tcttgttttt aatataataa cggctgaaca ggcgcataag aagtacaacc gttttaaata 15961 atccctaaac gtttttttct cacgattgaa aagaggcaga aaagtgtgag agtcagaacg 16021 tcgaagacat aataaagata catccgaaga ggcgagggct cacttcatcc tcatcatgtg 16081 cactcttctt gggatcctgg ctgttttctc ctcttcgggc tactgggtta ctctcttcct 16141 ctctccctct cttcctctct tcctggacta tatgaacctc tcatggcttc tccttatctt 16201 tttttgccag catctgcccg atatcttctc ctttcgttag catacgggcg tggagggaag 16261 tttcagatta attgaattta ctcaaatcaa gcttgaaaac gctattggaa atatgtctta 16321 gtaaatcgga ggaaaattta agcttccggt taaataaggt tatacggaat taagactaat 16381 tgatatttat gggatcaaca gcagaaatcg agaagagact tatcgaactc gataaggaaa 16441 ttcattccat cctcaacatg gttagaaaaa aagaaggaaa aagctcaaag gaaattgtag 16501 aatcggcctg tggggcatgg ggttacgatg tagagagtga agagtttgtt gaccagctga 16561 ggaaatcttc acgtctggat tgggtagaat gaaatttttt gtagacacat cgatatttgt 16621 tgactgtctt cgaaaagagg tcattccgtc ttccaaaagc tttctggaac gtatcggaga 16681 tgaatattca ggttatacgt catcaattac cgtcgccgaa ctgagtgttg gcgctcacct 16741 ttcaagatcc caggatgccc ttgaaaaaac acttgaacta cttaatattg tagaagtaat 16801 agatcttgat tcgagaatag caatagatgc agggaaaatt tatgctgatc tcatcagaag 16861 cggaaagaga attgagttga atgactgcct gattgcagca acagcccttt ctctaggcat 16921 aaatagagaa tagtaaccag aaacaaaaaa catttcattc gaatagaaga tattgaagca 16981 gtaactcctg aagagacttg gatttaatct tgatccaacc aattgaaaac ttgatttcaa 17041 aacccctact attttctatt cttcgatttt ctttcgagtt catgctaaac aataccgaat 17101 acaactggta atttagacat tggagacttc cacgagggtc aggtaaggtt tggatacttg 17161 ttgcgaaagg tcttcagtcc caaagctctc aatgtacagc tctatagctt ctttaatatt 17221 ttcttcggtt tcttcaaggg tttcaccctg agaagtcaca ttgagttcag gacatcttgc 17281 aataaaaaag tcatcttctt ttgttatagc tacgagaaat tgtctcatgg tctactccaa 17341 gtctggtttt cacatgtttt tcttcaaata tttgttgcga ttctatttta tattggcgta 17401 gaaactgtcc agtcaggtag tgtgcttagt ttacaaaact tgctttatac cattaatttt 17461 agagagattg aaactcaatt tatttttgtg tgtaggtttt accataaaat ctgtgcatat 17521 tcatggttga gtttttaggt tctgtccttc ttttttgaca gtgggaccgt ccggtatctg 17581 ctcacttcgt gggcatgcgg gcgtgggggg acgttttaaa atgaattttt aaaaaaaatt 17641 gaaaactctt tcataatcaa caaggtgctg cttgatccct acacctaaaa ctctcctatt 17701 tttcaccgtt gaaattatta gcgttatcta cacgaacatg gggtggagta gagttcatcc 17761 cgggatgatg aatcttaaag caaaataatt ttaggattga acaatctgtc tcttgtaata 17821 aattattgag aatgatggct taaaagttat gaaagaataa tgaacagtaa tttggagaga 17881 gataagacga aaaaaaacat atggttcgtg attgcctcgt tgagttatat tatagcaatt 17941 ggttttatta ttgcatattt tatcggtgga tactttccct atatagttat agctgtgatg 18001 tgggcgtgta taggaagtct ggatatacag tacttctcta attttcattt cctcataaac 18061 gaggctgttc gataccttta tatgtgataa aatctgcctc cgtatgtctt ttccgccata 18121 taaatctgga tatgccccta aaattgaatt aaaggcaaaa gaatgtattg atgccgtatt 18181 aagacctctc aatgaccatg taaccataaa gatcaatggt tcccttacaa gtgaagacgt 18241 ttttcgtact gttgtaagta tggcagtcaa caggaattct gttcattcag tctcaacaca 18301 gtatcaggat gttgcttgtg aaacctctct tcgataccac cttaagaaac tggatatgga 18361 tgaactgatc aaatcgaatg aaaagattct ccttcaagaa ctaatagaaa ccctaaaaac 18421 aggtaaaagc tacgaattcg ctgtcgatta taccaatgat ccctattacg ggaaaaaaga 18481 ttcatctaac gagaaatatg taataggtgg acaggctaaa aagtcaacaa actcatttta 18541 ctcgtatgtc tccctttata tcattaacaa aactgagagg tttaccttat cagttcttcc 18601 tgtcgaaaag aaaaagacaa aggttgaata tctctcccat ttcattgatc tcatcaaaag 18661 actggacttt aaaattaaaa ttctctgcct ggatagagag ttttgtacta ttgacgtttt 18721 taaatttttg caaagtaagc agattccaca catcgttccg gttattaaaa aaggagagcg 18781 gatgaagaaa ctacttaagg gaaataaggc gcgtaatgaa caatatgtta tggggaactc 18841 taagaaaaat attcttttgg acattgtaat tgacgtcaag tatctgaaag gcaaaagagg 18901 aaaaaaggga cgtaagaacc ttggttttgt ggtttttgga gtcaaatggt ctccaagaaa 18961 ggtcagtacg gtttacagaa gaagatttgc tattgaatcg tcgtacagga tgagaaatgt 19021 agttaaacca aagacctcat ccaaaaacgc cagtatcagg tacttttatg cactgatatc 19081 tttcctgtta aaaaacgtat ggctatttct tcagaaaaag cattttacga ttgtcaaaag 19141 aggccctcag gtaatagatg aggacaagtt cagatttaga atgtttgtag ttctaattga 19201 ggaatggttg aaaagaaagt tgagagttag gttaatggtg gagtgtttga ggtaa //