LOCUS NC_002695:7 19390 bp DNA linear BCT 17-AUG-2011 DEFINITION Escherichia coli O157:H7 str. Sakai, complete genome. ACCESSION NC_002695 SOURCE Escherichia coli O157:H7 str. Sakai, complete genome. COMMENT locus start: 1417912; locus end: 1437301 FEATURES Location/Qualifiers source 1..19390 /organism="Escherichia coli O157:H7 str. Sakai, complete genome." gene complement(0..224) /gene="" /locus_tag="" /db_xref="1417912..1418136" CDS complement(0..224) /gene="" /locus_tag="" /product="hypothetical protein" /translation="VTFQGNNSFMRLAGQVLITLITWRSHVSGSIPLSFAATDQAVHH CRTIARHLKVLSRQQEGIILSRHFSRGPVR" gene complement(458..2548) /gene="" /locus_tag="" /db_xref="1418370..1420460" CDS complement(458..2548) /gene="" /locus_tag="" /product="Iha" /translation="MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAA SVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDG VRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN ADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGSSVTSL SDTAATRIPYPTESQNYNLGARLDWKASEQDVLWFDMDTTRQRYDNRDGQLGSLTGGY DRTLRYERNKISAGYDHTFTFGTWKSYLNWNETENKGRELVRSVLKRDKWGLAGQPRE LKESNLILNSLLLTPLGESHLVTVGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDE WHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLH KGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTGFMTDFSNKIVSY SINDNTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSY TPEHMVNAKLNWQITEEVASWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAW TVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYV IPERNYWMSLNYQF" gene 3947..4219 /gene="" /locus_tag="" /db_xref="1421859..1422131" CDS 3947..4219 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LPGNWTYNYSSVLKERSEMFKYAEMLMAEEDDKVCELIFKQQDN LILKINVRFPRIIIKKYRTLQGKVVWLWILPFVIEWLIVCTLGVNS" gene complement(5968..6162) /gene="" /locus_tag="" /db_xref="1423880..1424074" CDS complement(5968..6162) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MNENKIKRLEQLLQARQREFATKWGRAALPHERLTYFPLEDLIK NNGKKIRSDKKHFLECNEDK" gene 6242..6466 /gene="" /locus_tag="" /db_xref="1424154..1424378" CDS 6242..6466 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LELSSTKGDEARLYRNGSMALMPVCCSIMASLSIRCCSSRKNFA SSGDKSIVITRKAMRCSALRYRADGSYPFY" gene 6482..6754 /gene="" /locus_tag="" /db_xref="1424394..1424666" CDS 6482..6754 /gene="" /locus_tag="" /product="hypothetical protein" /translation="VSYQPGGLVLPDLSRRGYLSKNASSSNRFGLVNGDGLSKDSRCW CTFSRWRSSMDNAIACSSSLVIVCTWEAIYRSTSHYGKNVLLLQLA" gene 7059..7253 /gene="" /locus_tag="" /db_xref="1424971..1425165" CDS 7059..7253 /gene="" /locus_tag="" /product="hypothetical protein" /translation="LCHRAHQSCTTRDVALDRHLPDCEDILKEVIWAFSDFVRDNRGV YDPEARYPAGNPWYPVTGQF" gene 7319..7516 /gene="" /locus_tag="" /db_xref="1425231..1425428" CDS 7319..7516 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MLTTTSHDSVFLRADNSLIDMNYITSFTGMTDKWFYKLISEGHF PKPIKLGRSSRWYKSEVEQWK" gene 8246..9370 /gene="" /locus_tag="" /db_xref="1426158..1427282" CDS 8246..9370 /gene="" /locus_tag="" /product="putative glucosyl-transferase" /translation="MRKRILFIGPPLYGLLYPLISLAQAFRVIGHDVVISSAGKFANK AAEAGLVVFDAVPGLDSEAGYRHQEELRKKSNIIGHFSFFSDEMADNLIDFAGKWRPD LIVYPPLDPAGPLVAAKYRIPSVMLAVGFAHTSAHIQMLNRSLSNAYRRHGVSGPLCD LAWIDVAPPSMSILKNAGEPVISMRYIPYNGGAVKETWWDRDSDRKRLLISLGTVKPM VDGLELISWVMDSANEVDADIILQLAINARTGLRKLPSNVRLVDWIPMGVFLNGADGF IHHGGAGNTLTALYSGIPQIVFGEGADRSVNAEIVAKRGCGIIPDKHGLTSDLVNRLL YDDSLRFCSDQVAAEMAEQPSPAEIAEVLMRKLKNNGKQL" gene complement(9789..10292) /gene="" /locus_tag="" /db_xref="1427701..1428204" CDS complement(9789..10292) /gene="" /locus_tag="" /product="transposase" /translation="MSRQCTHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMD EQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVWMTDG WPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHY LNIKHYQ" gene complement(10211..10486) /gene="" /locus_tag="" /db_xref="1428123..1428398" CDS complement(10211..10486) /gene="" /locus_tag="" /product="InsA" /translation="VASISIRCPSCSATEGVVRNGKSTAGHQRYLCSPCRKTWQLQFT YTASQPGKHQKIIDMAMNGVGCRASARIMGVGLNTVLRHLKNSGRSR" gene complement(10724..11182) /gene="" /locus_tag="" /db_xref="1428636..1429094" CDS complement(10724..11182) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MKIYWTRKRIPELSALPPSLRKKNFTDAYNAASSHIEYWIGAGV SFISMMILSRVYDFLLPAQDTFPGDIIRSLCVVCPSILIWFQFSVYVMRKYYRHILVR GKETETISERLIREADTREYELWRPVRRFFSIVFLIVLLGCIHSLITTIK" gene 11247..11438 /gene="" /locus_tag="" /db_xref="1429159..1429350" CDS 11247..11438 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MTTSPFILEFHDNDRDNHYQLIVSVILTYITLSWFNQVIDLMKR VCLWMYCVYVLPGICSYIN" gene 11640..12149 /gene="" /locus_tag="" /db_xref="1429552..1430061" CDS 11640..12149 /gene="" /locus_tag="" /product="hypothetical protein" /translation="VQITEALISEPGEIRRFVQQAVDHWPNLLAFHFTLYSAEGIYGQ QIQTFCSSFHRRVHERITEHNHTVSPSAPVVLRWLREQHEGAQIRCLLLLSQTSICHP RVGVMADEECAQLVDLLQQTWSVISAGGQCRVERCFRVARPGSSGQYVALKTAVQSFM SQVIATIIR" gene 12238..12861 /gene="" /locus_tag="" /db_xref="1430150..1430773" CDS 12238..12861 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MRTRIDYLADKYCFTERNESPRLRRQWQDVLEECRQTEAGPEER LRIALLNVDYVTSFELPFRLLLTRTPQLIAALREEWGISQKNVVFNDKRFGCVYSLKA SLSGVPDTYRYHLSHRIRRVVGNENTSLPYQQVAREVKAPRERLKYALEAGLLVTALD GLFRFGSQRIAADVLRLRKAGMPVVTTTVEVHDNLTGTTRKVPAYHL" gene 12957..13190 /gene="" /locus_tag="" /db_xref="1430869..1431102" CDS 12957..13190 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MARSDYDIINLSLEHELNEWLAERGYAGLVDNRNRLAEVVTRKL QDSFYINVSRDALNTAYSEHPEWFSGLVSGDEN" gene 13201..13416 /gene="" /locus_tag="" /db_xref="1431113..1431328" CDS 13201..13416 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MLLSGSVIAGRDFVLFCFFPGFGFEFSQKVVHRSHAGMRIAVLH KHHPGFLNTGQGDKRTMIVFVSLIDFR" gene complement(13243..13434) /gene="" /locus_tag="" /db_xref="1431155..1431346" CDS complement(13243..13434) /gene="" /locus_tag="" /product="hypothetical protein" /translation="MSEDVPLPKVNQRYKDDHGALVTLTSVEETRVVFMQDGYPHPCM RPMYNFLGKFKPEPREETE" gene complement(14028..14915) /gene="" /locus_tag="" /db_xref="1431940..1432827" CDS complement(14028..14915) /gene="" /locus_tag="" /product="putative transposase" /translation="MPLLDKLHEQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARA QRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGK KVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGCIV GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYISLAYTERLKEAKLLASTG STGDSYDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHIP PAEAEKAYYASIRNDDLAA" gene complement(14915..15241) /gene="" /locus_tag="" /db_xref="1432827..1433153" CDS complement(14915..15241) /gene="" /locus_tag="" /product="putative transposase" /translation="MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTP ETLRVWVRQHERDTGSGDGGLTTAERQRLKELERENRELRRSNDILRQASAYFAKAEF DRLWKK" gene 15734..16468 /gene="" /locus_tag="" /db_xref="1433646..1434380" CDS 15734..16468 /gene="" /locus_tag="" /product="HecB-like protein" /translation="MSTLQNRLVDHGYVTTRVLAPSQDLKSGILRLVIIPGVVRHVRL TPDSDDYIQLYSSFPAHEGSLLDLRDIEQGLDLGNSRIQGQHTELNATSGNLSTQNAQ LSADTLSARTAGQFSSNGGTINADTLQISAQSLSNRKGSLIQTGTGDFSLSLPGSVDN REGLLAANGAVRLDALSLDNRKGKVQAEQSPSLQKSPPTFLKPFVAGVCAALLAVSVA IPGWQFLTQPSPEEQHFTWGNGCKKQ" gene 16709..17224 /gene="" /locus_tag="" /db_xref="1434621..1435136" CDS 16709..17224 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MVTICVDGENKTHKITDWTLWAGNDDREVMLTCHFRSGRKYTRP LSVCQITPTVNLRNVFLERKGNAVTSRAELVIIYGDKYAAVYYREGERPYIMKTTGLD FQQCSAFTEHAVFNYLCRVANERIFYARGNNRNIDENILRQIKKIVPHPDTALHAYCS GQSKNVIRHGV" gene 17452..19389 /gene="" /locus_tag="" /db_xref="1435364..1437301" CDS 17452..19389 /gene="" /locus_tag="" /product="hypothetical protein" /translation="MARLGSTENRQQFFSTSISRSEEVLPDSPSANAIDDVLQQVKKH LNAINQVASLKAEINELNIEYKYLQQWQSQNLRPEELFSHKYRFSSQKTTDLMAYIHY LSDRRIGFRNRIDLLLNFMILKVKPLMIPERRLALFTSLQLSYYEKNIREKQISLNEY EEAFKKSDFKILLGRLTSWSMLYLKQHLRRNVSTRSSFSAETYRDEFDRFIKRFPIIG SSTHSIINSIGKGALLDYVIIDEASQQDIVPGILGLGCARNVIVVGDRKQLPHVPVLL PNSPSPPAEYYNCEKYSLLDSVCMLFRNMVPVTLLKEHYRCHPKIIQFCNKQFYDNAL IPLTVDSGEASLSLVITAKGNHTRNFSNLRELESLEGHYWDEESSRGYIAPYNAQVNL AEKVLPADFVKSTVHKFQGRECDEIVFSTVLDKKRSSQHSRNIAFVDNPELVNVAVSR ARNKFTLVTGNDVFERHAGHIAALIRYIKYYADDGEIFESPVISAFDLLYSEYDKSLE RLNSRLNSNDSHFKSEQIVACLLRDILSQDSYRSMMFHSQIALNQLVLLERGDFTHRE QLFMRNRASCDFVVYYKVGKTPLGVIEVDGGYHLTSVQAERDELKNSILKKCGLPLLR LRTIDSDIEGKLGAFLSGLTG" ORIGIN 1 ttatctgacc gggcccctgg aaaaatggcg ggagagaatg ataccttcct gctgacgaga 61 caggactttg agatgacgag cgatagtgcg gcagtgatgt acagcctgat cggtagctgc 121 aaaacttaac ggaatcgagc cggaaacgtg gctacgccac gtgatcagtg taatcaacac 181 ctggcctgcc aaccgcatga aagagttgtt gccctggaac gtcactctct ctgtaaacta 241 atttttaccc cacgtccttc acggtgcgct tacactctgg acaagtatgt aaatgataag 301 ttaaaaataa tccgtgcatt tcctgtgacg atattagttg ttggtaacga aatctcatta 361 gcggatcgga aatgcactta acctaatacg ttgccactgt tccgccagga gttgcagtgg 421 caacgtattc taccgtcagt gatagcgttt tgttattatc agaactgata gttcagcgac 481 atccagtaat ttcgctcagg tatcacatat cctgttgttg atgatcccgt ctggaagtaa 541 tcaccggcat acagcgtact cttaccggca ctgtacaggc tcacgtcact gtaatccttg 601 ttgagcaggt tattcaccgc agcattcagc gtcagggcat ccgtcatctt ccacgacaga 661 cctgcatcca ccaccgtcca ggctttcagg tattctcctt tctcatcata cactttcttc 721 tgtacagcgc tcagtgacga ataattctgg gtgaaacgtg gtgttttccc gcgataacgg 781 gcacccagcc atgatgccac ctcttcggtg atctgccagt tcagtttcgc attcaccatg 841 tgttcagggg tataactcag cggcgcacct ttgttatcac catcacgttg ttcacttcgg 901 gtccaggtgt aattcagtga cagcgtgaca tcctctgacc acagcggcaa tgtgccggca 961 aattccacac cgtgcaaccg ggcctttccg ctgtttacat agctattggt gttatcattt 1021 atggaataag agacaatctt gttggagaag tcagtcataa aacctgtgac attggcattt 1081 agaccggcgg ggttatcgta atacacccca gcctcataac tgacgctctc ttccggcttc 1141 aggtcggggt taccaagtag atttgttttt ccctgcccgg acacaccact aatcccttta 1201 tgtagctgcc ccattctggg tgccttatat cccgtggtca caccgccttt cagcgtccag 1261 gcatctgcca catcccagac cagatatgca cgcggactga agtgtccccc gaattgctca 1321 tgatgttcat agcggctgcc cgcagtcagc gcaagtgcat ccgtgagatg ccactcatcc 1381 tcagcaaata ccgaccagct tttctgccgg aaagtttcac ctgtgctggc aaggacaact 1441 ccgtctttca tggacgagct ctgaaactcg ccccccaccg taaccagatg agattctccc 1501 agaggggtaa gcagtaatga attcaggata aggttcgatt ccttaagctc ccgcggctga 1561 ccggcaagcc cccatttgtc gcgcttcagt acactgcgta caagctcacg acctttattt 1621 tctgtctcgt tccagttcag atacgatttc catgttccga aggtgaaagt atgatcatag 1681 ccagctgaaa ttttgtttcg ctcatagcgc agggtccggt catatccccc cgtcagactc 1741 cccagttgcc catcccggtt atcataacgc tgccgggtgg tatccatatc aaaccagagc 1801 acatcctgct ccgacgcctt ccagtcaaga cgtgcaccaa gattataatt ctgtgactcc 1861 gtgggataag gaatacgcgt ggctgctgta tcgctcagtg atgtgaccga tgaaccctga 1921 cgctgttgtg tgctaccgcg tacctgcagg ctgacagaat catccacaag gggaccactg 1981 ctccagaaat taaactggct gctgttaccc catttgttgc tttcctgcag attcagccct 2041 gcattgacgg aagagagcca tttgtctgca ttctttctgg taatgatatt caccacaccg 2101 cccatcgcat cagagccata cagtgtggac atcggccccc tgataacctc aatacgctca 2161 atggcggcca gagggggcat gaacccggta ttcatggcag aaaaaccgtt gggagtcacg 2221 tcactgcttc cgccctgacg aacaccatca atcagtatca gcgtgtaact ggctggcatt 2281 cctcggatgc tgatttccag ccctccggtt ttacccgtac cactttcaac atccacaccc 2341 tctactgatc tcagagcctc cgccagatcg tggtactggc tggactgcaa ttcctcctgg 2401 ctaatcacag aaacactggc ggctgcgtta gtcagctttt tctcatagcc ggatgccgag 2461 acaatcatca catcctctgc agcagctatg ctgctggctg aaaatccgag acagggaatg 2521 actacggaag ccagagtggt tattcgcata ttactaatct ccgatcatgt taaccggcaa 2581 gacaatacac aaatacaaac aataatgaga ataatttata tttgcctttt acaaaaaata 2641 aagattattg acaaaaccaa atataaataa cgactgcctc ggcatgccag ttaacagcta 2701 tccgtatggc gtgttcggtt ttgcgaataa aaaatggtta ctgtagaagc ggatttccac 2761 cacatgtcaa ccatgaatgg tcagtgatgc gagacgactg ggatgatttg gtcgatgact 2821 tcttccggcg aatactgata gaaacattga aatattgtaa gagaaagcgt tcaaaattct 2881 gtggcacgtg aaaaattcta cagcgtcatc accttattca gtcgaccttc aaaataaacg 2941 tttaacagag acaatcacca tttggattgt ccgctgagga ggcgaacaat ttcctagaca 3001 gctttatcat gtcagcccac attgttggcg ctggcaatac taaggacaaa cgatggggaa 3061 gtagcttttt agcgttattt tcgggagtaa aaaacgtggt atctttccgt atgtcagttg 3121 tatcttgctg gtattcgtag tcgtgataag gcatacaacg atatttatct tgacgttagt 3181 gaagaataag ttgttttgtg atctatgtta atctgggatt acaatccggg cttgatacat 3241 cgcatcacga cttttattct cttcagaata gaatatgtta ctccccgctt tacaggctca 3301 ggatttgaat tacaaattat acttttaagt gaacaataac caagggtatt tcttatttcc 3361 tgaaaccagg cttggcccat ttcgggatga gtttgaaaaa actcttgacg catacgatag 3421 tgatgaaata aacgaaacaa attacgtcaa caaactcagg cgtcttgcct gacatgctcc 3481 tgacatcatt gatattcacg ctcatctggc atatgcattt gcgctcttta tgctgcaatt 3541 ctggcgaatg ttcatttaca gcgtcatcag gatgccgtta tactcattga taaaatacta 3601 acatataacc ctgagaataa tcagggaaca cgctggttac tgggggcgga attgttacgt 3661 gctggcaagc atggcagggc tctgtacgta ttgacaggac atgtcaatga atttcccccc 3721 tactggtacg agcttgctct tttacatttt atgaatgagg catatattaa tgctgcaacg 3781 gcatttcgat atggattttt aacaagtata tattgttgaa atgctttgtt agaatcttta 3841 tccattccct agggctgtat agtatgattt ttcaggtatt tctgaatact gccaaatatt 3901 attgcaaaat attctctaaa ttatgaatta aatatccata agcattattg cctgggaact 3961 ggacatataa ttactcttct gtgctaaagg aacgttctga aatgtttaag tatgcagaga 4021 tgttgatggc ggaagaagat gataaagtat gtgaacttat ttttaaacaa caagataatt 4081 tgattttaaa aataaatgtt agatttccca gaataattat aaagaaatac cgaacattac 4141 aaggtaaagt cgtatggcta tggatattgc catttgttat tgaatggtta attgtgtgta 4201 ctttgggtgt aaacagttag cttggtaaaa gtaaatatcc tgattgttgt ttgttaagga 4261 gtgagatgcc tgtgcgtctg gtgtctatta tattcccaat attattggcg ctattcttgc 4321 tggcgtaggc atcgccatac tatgaatatt gtgtttgtcg tgattcaatt tttatttata 4381 acctctaccc ggagcaaatt caggtaggtc atgcataaaa atatctttct atactacgaa 4441 aattattttt gtgaaagtat tgacaacgct aactattttt aattatatat tcatgatgct 4501 ctaggcatca cattttctcc atggggtatt ccctccgccg gcactatgtg ttgctggcgt 4561 ttttttatca attcttactt tttaatccca ctgtcctttc caccagaaac atacctcgtt 4621 tctactgtat tttgagaata tagttcccag aataccaatt atatataata cgttgtaata 4681 tatgtattcc aattaaagcc gttattataa taattatcat atatggttat tttcatattg 4741 atttcgtcag aaatagaaaa tgctgatgat gaattgtgaa taatcaaact gacctctaat 4801 tatcctgtat ggagtagtgc ttattttcga ctcaatttct actgattaga ttatggttat 4861 cagtacagtg ggttatgaaa aacggactgg atctgccagc agtgcttcta ttattattca 4921 aaaagaactt cagccggaca atgctataat ccagggaaag gctataagct ctgttggacg 4981 gaatgtggaa atcagcactg gtaaaagggg aactgacatt aacacaagaa ggattcctgc 5041 aagcaactgc ttatctgccc ggaacgcaga attaaagcat aaccacacag gagccagaat 5101 actgtggtcg tacgcattca gtattgtgac aactaataga aataaaaatc tggccggtgc 5161 gaatattaaa cgatgcgata ccgtatagtg taagtcaaaa gtaacggggt atttaaacca 5221 tctttttata tttatttaac ataatgcaga ttctgatgta ttagttcagt tgttcgccag 5281 aatcagcgct cgatcactat gcgttttagc agtgtgctga agaagttctt catcactgcg 5341 ttattcagac cgtttccttt gtgcggcata ttttgtgcta ctccatgggg ctttaacttt 5401 gcctatagcc tgcaattcga tattgccaac cctgatccat atgcagcgac ggggcatcct 5461 ctggccgggc actgtgaatg catcgtatag catcgtatta acgatgctcc atcaccgacc 5521 tttctgacaa gctgtaggag ataatttccc ggttaaacag atcggagaac tggcgacagg 5581 taccactttt cccctgtacc gagaactctg taacatccgc tcccattttt cgttggcctt 5641 tgtcaaagtt ccggctcagg atattgggcg cagatcactt atttggtgga caccactttg 5701 tcggatgctt cagattatga ccagatggat ttcgctggac gcttacgatt acatgcacca 5761 tattgtcaac gattacgcca ctgagtgtat gacacacatt aaagcgttag gctcaggcct 5821 tattacaatg tcatgctagt gtgcttgtac gccgtaaata tctgcatgat accagaatga 5881 ccggcaaact cgtcagtgga tataaagaaa atcaagtgcg ctgataacga tgccacatct 5941 gtggttggtg gcaatatgca gattgttgtt atttgtcttc attgcattct aagaagtgtt 6001 tcttatcaga cctgattttt ttgccattat ttttaatgag gtcttcaagt ggaaaatagg 6061 ttaggcgttc atgtggcagc gcggcacgtc cccatttagt ggcaaactcc cgttggcgtg 6121 cctgtaacag ttgctccagc ctttttattt tgttctcatt catccggttt tcctcgtatg 6181 ctgcatcaca ccactgtgct aatgaaaaat gtaatcagtg tggtggacgt gttttatccg 6241 cattggaatt gtcgtcaact aaaggagatg aggcccgttt gtatcgcaat gggtctatgg 6301 cgctcatgcc cgtttgctgt tcgataatgg cttctctgag catacggtgt tgcagttctc 6361 gtaaaaactt tgcgtcttct ggtgataaat ccattgttat tactcgtaaa gcaatgcgct 6421 gtagtgcctt acgctaccgc gctgatggtt cttatccgtt ttattgaatc ggagaacaaa 6481 ctgtgagcta tcagcctggt ggtctggttt tgcctgattt aagccgccgt gggtatttgt 6541 ccaagaatgc ttcaagctcc aatcgttttg gcctggtgaa tggagatggg ttaagcaaag 6601 actctcgttg ctggtgtact ttttcgcgct ggcgctcaag catggataat gcgattgcct 6661 gtagttcttc gttagtcatt gtctgcacct gggaagcaat ttaccggagt acctcacact 6721 acggcaaaaa tgttttattg ttgcaacttg cgtaattatt caggtcagtt tggaacgcac 6781 tgtataaaca taaataacct gatactgttg tgtgttttca aagaaaacac aggtattttt 6841 cacataaacc ttcccctttt catatccgac cacttaatca aaaaacggtt ttatacttgt 6901 tgcccccact ggggtcatct tgggtgactt ttaacgtcag gtgacgcatt gtcacttcag 6961 acctgctacc tatacgccgg aatataatgg tcagagaggc atatttcgac gcccctaatc 7021 tggggcgttt gattcaggat gtctggaaca atccgggctt tgtgtcaccg ggcgcatcaa 7081 agctgtacca cccgggatgt ggcgctggat cgtcatttac cggactgcga agacatactt 7141 aaagaggtga tatgggcgtt cagtgatttt gtccgcgata atcgtggtgt gtatgatccg 7201 gaagcccgtt accccgccgg taatccctgg tatcccgtaa caggccagtt ctgaaagcac 7261 agctcagtag atttcccgca ttcgcacaat cttcataaat ctcacaggac attctgacca 7321 tgttgactac aacaagccac gacagcgtat ttctgcgtgc cgataattcc ctgatcgaca 7381 tgaactatat caccagtttc accggtatga ccgacaaatg gttttacaag ttgatcagtg 7441 aaggccattt ccctaaaccc atcaaactgg ggcgcagcag ccgctggtac aaaagtgaag 7501 tggagcagtg gaagtgaagt agagcagtgg atgtagcaac gaatcgagga atcctggggg 7561 gcagcagcat gaaacgtgtt gtaatgccgg tacgctggca atgtgcaaaa tgccagcgct 7621 ggtattgtgg aacccggccc tgcccttggt gctggcgata ttcccgttca tcttcctgct 7681 gataccttcc gttcagcagc gggttgttat cccttcctga ctgattcgtc attccattct 7741 tattgattag aactggcatt acaccggtgc cggcgtgctt tcctgcgtgt ctgcgccggt 7801 tcagtaaatt agaaaagaaa catttgtcag cgccagtgat ataaggcgta acggctaaca 7861 atcttggcgt taatacattc cgagcaaata accgaagcgt tacttttagt gacggggtta 7921 tccaatactt ttctagtcag tgtttagtat ttatgcaagc gatataagta gtcaccgctt 7981 agactattga cattcatgat gcctgttaat tcaaatttca ggtatgatca gtcatttatt 8041 gttgtgatac tgattccgct agtttagcat aactgtcctg caaatcattg ttcaaaaaag 8101 aaagctccta caaactgtat cctgaatctc taccagaaga taatatactt ggttattttt 8161 gtgcataagc tcacataaaa ataatattaa ttatgttttc ttagagatag aaaaataaac 8221 aggtaagcag aagacggact tttttaatgc gaaaacgtat tctttttatt ggcccaccgc 8281 tgtacggttt gttataccca ttgatttctc tggctcaggc ctttcgtgta attggacatg 8341 atgtagtaat tagtagcgct ggcaaattcg cgaataaagc agcagaagct ggactggttg 8401 tttttgatgc agttccaggt ttagattcag aggctggata tcgccatcag gaagagttga 8461 ggaaaaaaag taatattatt ggtcatttct ctttttttag cgatgaaatg gcagataacc 8521 tcatcgattt tgcaggaaaa tggaggccag atttaatagt ctatccccct cttgatccgg 8581 caggcccatt ggttgctgct aaatatagaa ttccttcagt gatgctggct gttggattcg 8641 cgcatacatc tgcccatatt cagatgttaa accgttcttt aagcaatgct tacaggcggc 8701 atggagtcag cggtccacta tgtgatttag catggattga tgttgctccc ccaagtatga 8761 gcattcttaa aaatgctgga gaaccggtta tctcaatgag atatattcct tataacggag 8821 gtgctgtaaa ggaaacatgg tgggacaggg attctgatcg gaaacgttta cttatcagcc 8881 ttggcactgt aaaaccaatg gttgatggtc tggagctgat ttcatgggtt atggattctg 8941 caaatgaagt tgatgctgat atcattttgc aacttgcaat aaatgctcgt actggtttac 9001 gaaaactacc atcaaatgta cgtctggttg actggatacc tatgggtgta ttccttaatg 9061 gagctgatgg atttattcat cacggtggcg caggtaatac cctgacagcg ctgtatagtg 9121 gaataccaca gattgtgttt ggcgaaggtg cagatcgctc tgttaatgca gaaattgttg 9181 cgaagcgtgg gtgtgggatt attccggaca agcatggact gaccagtgat ttggtaaatc 9241 gccttcttta tgatgattca ctacgcttct gttcagatca ggtagccgct gaaatggctg 9301 aacaacccag tcctgcagag attgcagagg ttttgatgag aaaattaaaa aacaacggga 9361 aacaattgta gcgtattgct gaaattttca acgagaaatg ttatgagtaa tataatgtcc 9421 ttcatcacat aaatgaagga catcactaaa taaatgagat agtctcccat aataatattg 9481 cagaaagagt tatctgacga taaaacgata ttttacacag agttattatt tgataccttc 9541 ctgcaattat aatttgctaa ttcatcaata attgctccgc gccaccaggc ataatcgtga 9601 ccaccggtat agacagtgag gttactttcc aaaccagctg cgattaacga atgatgcaat 9661 cgctgaacat gtgagacggt tgtaccttct aaagaaccga ctccaagtcg aatatttaca 9721 tctttcggag gcgctgaaag tatctgctca cttacccagg aggtattatt ctcaggtaat 9781 gactccaact tactgatagt gttttatgtt cagataatgc ccgatgacct tgtcatgcag 9841 ctccaccgat tttgagaacg acagtgactt ccgtcccagc cttgccagat gttgtctcag 9901 attcagatta tgtcgctcaa tgcgctgagt gtaacgcttg ctgataacgt gcagctttcc 9961 cttcaggcgt gattcataca gcggccagcc atccgtcatc cataccacga cctcaaaggc 10021 cgacagcagg ctcagaagac gctccagtgt ggccagagtg cgttcaccga agacgtgcgc 10081 cacaaccgtc ctccgtatcc tgtcatacgc gtaaaacagc cagcgctgac gtgatttagc 10141 accgacgtag ccccactgtt cgtccatttc agcgcagaca atcacatcac tgcccggttg 10201 tatgcgcgag gttaccgact gcggcctgag ttttttaagt gacgtaaaac cgtgttgagg 10261 ccaacgccca taatgcgtgc actggcgcga catccgacgc cattcatggc catatcaatg 10321 attttctggt gcttaccggg ctgagaggcg gtgtaagtga actgtagttg ccatgtttta 10381 cggcaaggag agcagagata gcgctgatgt ccggcagtgc ttttgccgtt acgcaccacg 10441 ccttcagtag cggagcagga aggacatctg atggaaatgg aagccacgca agcaccttaa 10501 aatcaccatc atacactaaa tcagtaagtt ggcagcatta ccagaaaatg ataaggtaaa 10561 cattgaaaag cagccgactg atgactgttt tttatagttg catttttatt ttttgttatt 10621 ttcatttata ttcccttact tgtcgtttaa aattcttcta tataacagga agaggtaacc 10681 atagaatgaa cgtttatttt cctgtatcag aacagccata acttttattt tatagttgtt 10741 atcagtgaat gaatgcaacc taatagaaca atgaggaaaa caatggagaa aaagcgacgg 10801 accggacgcc atagttcata ttctcgtgta tcagcctcac gtatcaacct ttctgaaatg 10861 gtttcggttt cttttcctcg caccagaata tgtctgtaat atttcctcat gacatatacc 10921 gaaaactgaa accagattaa tatggatgga cacacaacac ataaacttct gatgatatca 10981 cccgggaaag tatcttgggc gggtaaaaga aagtcatata ctctggataa aatcatcatc 11041 gagataaatg agacgccagc acctatccag tattcgatat gagaagatgc tgcattatat 11101 gcgtcagtaa aatttttctt tcttaatgaa ggtggaagtg ctgaaagttc aggaatacgt 11161 tttcttgtcc agtatatttt catatagtaa ctcatataaa aagtgttcta ctttactatg 11221 atgatgacga tttataaaag gcttataatg actacttctc ctttcattct cgaatttcac 11281 gataatgata gagataatca ttatcaattg atagtatcag taattttgac ttacatcaca 11341 ctttcatggt ttaatcaggt gattgattta atgaaaagag tgtgtttgtg gatgtattgt 11401 gtatatgtcc taccgggcat ctgttcttac attaattaat atattgctat ttaagtattg 11461 gtagtattgt cagtaacatt cttttggtta atttagttat tattcctcac tgattaattg 11521 tccttccgtt cttattgttt gtaacttgtg tttgtatcgt acctttcagg tgttgatgcg 11581 cgctttactg tgtctgcacc ggcttgacaa aattcaacag gggttgaaaa ggaacatttc 11641 gtgcaaataa ccgaagcctt aatttcagag ccgggggaaa tccggcgttt tgttcagcag 11701 gcggtggacc actggccaaa tctgttggca tttcacttca cgctctattc ggcagaagga 11761 atctatggtc aacagattca gacattttgt agttcctttc accgacgggt acacgaacgt 11821 attacggagc ataatcacac ggtcagccca tcagcgccgg tggtattacg ctggttgcgg 11881 gaacaacatg aaggagcaca gatacgatgt ctgttgctgc tcagccagac gagtatttgc 11941 catccgcgag tcggcgtcat ggctgatgaa gaatgtgcgc aactggtgga tttactgcaa 12001 cagacctggt cggtgataag tgctggcgga caatgccggg tggaaagatg ttttcgggtg 12061 gcccggcctg gttcatcagg gcaatacgtg gcgttaaaaa cggctgttca gtcctttatg 12121 tcgcaggtta ttgcaacaat catccggtga ttgtcgggag gaatatcaat gcttccgtta 12181 atttttactg gctgataaag ttttgtctgc tgaatcttta tacggaattc ctttcagtat 12241 gcgtacacga attgactatc tggcggataa atactgtttt acagaacgga acgaatcccc 12301 ccgtcttcgc cggcagtggc aggatgttct ggaggagtgc cggcagacag aggccgggcc 12361 agaagaacgg ttgcgtattg cactgctgaa tgtggattac gtcaccagtt ttgaactgcc 12421 ttttcgcttg ctgcttaccc gtacaccgca attgattgcc gcgctgcgtg aagaatgggg 12481 catcagccag aaaaatgtgg tgtttaacga taaacggttt ggctgcgtgt acagcctgaa 12541 ggccagcctt tctggtgtgc cggatacata ccggtatcat ctgtctcacc gtattcgtcg 12601 cgtggttggg aatgaaaaca catcattgcc atatcagcag gttgcccggg aagtgaaagc 12661 gccccgtgaa cggctgaagt atgcactgga ggcgggttta ctggtgactg cactggacgg 12721 cctgttcagg tttggcagtc agcgtattgc ggctgatgtt ctgaggctga gaaaggccgg 12781 aatgccggtg gtgaccacga ccgtggaggt gcacgataac ctgacgggaa caacccgcaa 12841 agtaccggca taccatctct gatacaacca tcagggggaa tattgctctg gcagcagcag 12901 tatgacattc tttatacttt atccccgtgc ctgaaaacat gtgctaagga aacgggaatg 12961 gcaaggtccg attatgatat tatcaatctg tctctggaac atgaactgaa tgagtggctg 13021 gcagagagag gttatgccgg actggtggat aaccggaatc gcctggcaga agttgttacc 13081 cgcaaattgc aggacagctt ttatataaac gtttccaggg atgcgctgaa cacggcatac 13141 agtgaacacc cggagtggtt ttctgggctt gtctccgggg atgagaatta ataagtggat 13201 tatgctgcta tcaggtagtg tgattgccgg cagggatttc gttttattct gtttcttccc 13261 ggggttcggg tttgaatttt cccagaaagt tgtacatcgg tcgcatgcag ggatgcggat 13321 agccgtcctg cataaacacc acccgggttt cctcaacact ggtcagggtg acaagcgcac 13381 catgatcgtc tttgtatcgc tgattgactt tcggtaatgg aacatcttct gacataaatt 13441 ttagtacggt aacagttaac taaattttca tgtggtagca ctgaatcagg agactgcgtt 13501 tcctgatgtg cgctgttaat tttctgtttt tacgaaacat tttccccttc ttcctgtgta 13561 ttttattgcg ctcctccttt catgtccttc ccatatcctg aaactcactt aaatgctgtt 13621 gaatcgtcaa acattgcaac tttcaatgac tgaaatcaaa aattgctatt ttttaagcta 13681 accaactgta ttaaaagcat tcagtggaat aattttctgc acttttccag taattatggt 13741 tataaatttt gtaatgtgct gtttttgcga tatttgtcag aataaagaac tgttcatttg 13801 tgttatatcg atcgataaat ctgtcatgtt gctgtagttc agatcattat tctataatga 13861 tcaaaattaa gtcaattcta gctggtttgt tactcagcat tctggtaccg gttgatgcgg 13921 gtaaataccg gaagggcggt agcgtgccat cgcaaaacat ggtgggaggt atcgtcagga 13981 ggctggtgaa ccgccccggt tttcctggag agtgttttat ctgtgaactc aggctgccag 14041 atcatcgttt ctgatggaag cataataagc tttttctgct tctgccggag ggatatgacc 14101 cagccttccc agcaatcgtc gattgttata ccagtccacc cacgtgagtg tggccagttc 14161 cacttctgca cggtttttcc agctcttacg gtgtattacc tccgctttgt aaagaccatt 14221 gatgctctcc gccatcgcgt tgtcatacga gtcacctgta ctccctgttg atgccagcag 14281 ttttgcttct tttagtcgct ccgtataggc cagtgatata tactgagaac ctttatcact 14341 gtgatggact gtgccggacg gccgacgggc ccacaacgcc tgctccagtg catccagcac 14401 gaatgtcgtt tccatagacg atgagactcg ccaccccacg atacatccgg caaacacatc 14461 aatgatgaac gccacataga cgaagccctg ccatgtgctg acgtaagtaa aatcagccac 14521 ccacagctgg tcaggacgtt ctgccacgaa ctgacggttt acgcggtcgc ctgcggaaac 14581 ggctttccgg ctgacggtag tacggacctt tttaccccgg agaacaccgg caagtcccat 14641 aaccgccatg aggcgcgcca ctgtacatct ggccaccctg ataccttcgc gtaacaactg 14701 gcgccagact ttacgcacac cgtacacctg atgattttca tcgtatacgc gctgtatctc 14761 tctcttcagc cagtcatcgc gctgagcacg ggcactgcgt ttatcaggat gatgtcgctg 14821 ttgctgacag tggtaatacg ttgacggggc aatatgcagt tcactgcata ccggtccgac 14881 cccgtactgc tcatgcagct tatccagcag cggcattatt ttttccagag gcggtcgaac 14941 tccgccttcg caaaataagc ggaagcctgg cgaaggatat cgttactgcg gcgcagttca 15001 cgattttcac gttccagctc tttcagacgc tgacgttcag cggtggtgag tccaccatca 15061 ccactcccgg tatcccgctc atgctgacga acccacacac gcagagtctc tggtgtacag 15121 ccaatctttg gggcaatgga acaaattgcc gcccattgtg agtcatattc gccctgactt 15181 tccagaacca tacgaactgc tcgttgacgg acctcggggg aaaaacgtgt atttttagtc 15241 atcctgttta cctctttctc agggagttta gtctccagga ttcccggggc ggttcatggt 15301 gattgttggt atgacatgaa taaaaggttt ttcgtttgac tggaaaatta tgttgcagga 15361 acgagaggac tgaggaacaa agcttattcc ggcgctgtcc gtccttgctg tcactgacac 15421 tgatgtctgc tttattatcg cctttatctc ttcaggcagc ggatgtccgg cgtagcggag 15481 atgaagcatt tatcattcag cagcagcgtc aggaagccct tgagcaacaa ctgacgcctt 15541 cagcccctga tgttcgcctt tctgcacctg gctcttttgc ccataagatt aattttcctg 15601 ttgaaacgcc ctgttttcag attaaacaga cggaactgaa gggggctgat gcgttaccac 15661 actggctgcc tttacaaaaa atcgccaacg gggcggtcgg gcattgcctg ggggcgaaag 15721 gaattaatct gctgatgagt acattgcaga accgtctggt cgatcatggt tatgtcacca 15781 cccgtgttct ggcaccttcg caggatttaa aaagcggtat cctccggctg gttattattc 15841 ccggtgttgt gcgacatgtg cgtctgacac cggacagtga tgactatatt cagttgtatt 15901 cctcattccc ggcacacgaa ggttctctgc tggatttacg ggacattgag caggggctgg 15961 atttaggtaa cagccggata cagggacaac atactgagct gaatgcaacc agtggaaatc 16021 tgtctacaca gaatgcgcaa ctgagtgccg atacgctttc cgcccggact gccgggcagt 16081 tcagcagtaa tggcggtacg ataaatgccg acacactgca gatatcggca caaagcctgt 16141 caaatcgtaa aggcagtctg attcagacgg gaacagggga tttttcgctg agtctgccgg 16201 gaagcgtgga taaccgggaa gggctgcttg cggcaaatgg cgcggtgcgt ctggatgcac 16261 tgagccttga taatcgcaag gggaaagtgc aggcggagca gtcaccctcc cttcagaaat 16321 ccccgcccac gtttctgaaa ccgtttgtgg ctggtgtctg tgcggcattg ctggcggtca 16381 gcgtggctat tccgggatgg cagtttctga cacagccatc accggaggag cagcatttta 16441 cctgggggaa tggttgtaaa aagcagtgaa aacagtaaat acagagtatc gtgatgaatt 16501 agtgctcagg ggctaccagt attcaataac cagcgtatcg gcatcgcatt cctgtaattc 16561 tggtattgac tgttatgact aaattcaatg tatatatggc aggcagaaat atgttaacag 16621 tcccggagtt gtggaaaatc ctccggagct aatatcggga gtgccttaac aattttccgt 16681 aagttaaatg ataatttctg agtaagaata tggtcacgat ttgtgttgac ggtgaaaata 16741 agactcataa aattaccgac tggacgctgt gggctggaaa tgacgacaga gaggttatgc 16801 tgacctgtca ttttcgcagc gggagaaaat atactcgtcc gctttctgta tgtcagataa 16861 cgccaactgt aaatttgcga aatgttttcc tcgaaaggaa agggaacgct gtaacatccc 16921 gggctgaact ggttattata tatggtgata aatatgctgc tgtttattac cgcgagggtg 16981 aacgacccta catcatgaaa acgaccggcc ttgactttca acagtgttca gcatttacag 17041 agcatgccgt gtttaattac ttgtgtaggg tggctaatga acgtattttt tatgcccgtg 17101 gtaataacag aaatatcgat gagaatatcc ttaggcagat aaagaaaata gttcctcatc 17161 cggataccgc cttgcatgca tactgttcag gacagagtaa aaacgtgatt cgccatgggg 17221 tttgattttt ccgtttggtc ttaatgaaag tcagttgctg gctgtcgaac gggcattttc 17281 ctcacagatt tcagttattg aaggaccacc tggaacaggt aaaacacaga ctatactcaa 17341 tattgttgct aatatattaa ttcagaataa aacagtggca attttgtcca ataataactc 17401 agctgtcagt aatgtttatg aaaagatgga caaacagcaa ctgggatatg tgatggcacg 17461 actggggagt acggagaaca ggcaacagtt tttttcaacg tcgatttcgc gttctgagga 17521 agtcttacct gactcaccgt ctgcaaatgc gattgatgat gtacttcaac aagtgaaaaa 17581 acacctgaat gccattaacc aggtcgcttc gttaaaagca gaaattaatg agctgaatat 17641 tgagtataaa tacctgcagc aatggcagag tcagaatctt cgaccggagg agcttttttc 17701 tcacaaatac cgattttcct cacaaaaaac aaccgacctg atggcttata ttcattacct 17761 ttctgacagg cggattggat tcagaaacag aattgatttg ttgttaaact tcatgatact 17821 gaaagtcaaa ccattgatga ttccggagag aaggctggcg ctatttactt ctcttcagct 17881 ttcttattat gaaaaaaata tccgggaaaa acaaatttct ctgaatgaat atgaggaagc 17941 atttaaaaaa tctgatttta aaattttact ggggcgcctg acatcatggt ctatgcttta 18001 tttaaagcaa catctgcgaa gaaatgtttc aacaagaagt tcattctcgg cagagacata 18061 cagggatgaa tttgaccgtt ttataaagcg ttttccgatt attggtagca gtacgcattc 18121 gattattaac tctatcggca agggggccct tcttgattat gttattattg atgaagcctc 18181 gcagcaggat attgttccgg gcattctggg actgggatgt gcccgtaatg taatcgttgt 18241 aggggatcgt aagcaacttc cacatgttcc tgtattactc ccgaacagcc catctccacc 18301 ggcagaatac tataattgtg agaaatatag tctacttgat tcggtttgta tgttgttcag 18361 gaacatggtg ccagtaaccc ttcttaaaga gcattatcgt tgtcatccta aaatcattca 18421 attttgtaat aagcagtttt atgataatgc tctgataccg ttaacggttg attccggtga 18481 agcctcatta tctctggtca tcacggcaaa aggaaaccat acccgtaatt tttcaaatct 18541 cagggagctt gaatctctgg aaggtcatta ctgggatgaa gaaagtagca ggggatacat 18601 tgccccatat aatgcacagg ttaatctggc tgaaaaagtg ctgcctgctg attttgtgaa 18661 atcgacggtg cataaatttc agggacggga gtgcgatgaa attgtgtttt ccactgtgct 18721 ggataagaag cgcagcagcc agcacagtcg gaacatcgcg tttgttgata atcctgaact 18781 ggtgaatgtc gctgtttcaa gggcccgaaa taaatttacg ctggtgactg gtaatgatgt 18841 atttgaacgc cacgctggac atattgcggc gctgattcgt tacatcaaat actacgctga 18901 tgacggagag attttcgaga gcccggtcat atcagcattt gatttgctgt acagtgagta 18961 tgacaaatca ctggaacgac tgaatagtag attgaattca aatgattcac actttaagtc 19021 agaacagatt gtggcctgcc tgttgcggga tatcctgtcg caggatagtt atcggagtat 19081 gatgtttcat tcacaaatag cgctgaatca gttggtgttg ctggagcggg gggattttac 19141 acaccgtgaa cagttattca tgcgtaaccg ggccagttgt gactttgttg tttactataa 19201 ggtcgggaag actccattag gggttattga agtggatgga ggttatcatc tgaccagtgt 19261 tcaggctgaa cgtgatgaac ttaaaaacag tatactgaag aaatgcggcc tgccattgct 19321 aagattacgt actatagaca gtgatataga agggaagttg ggagcgtttc tgtcaggcct 19381 gacaggctaa //