LOCUS AP010958:23 18269 bp DNA linear BCT 27-AUG-2011 DEFINITION Escherichia coli O103:H2 str. 12009 DNA, complete genome. ACCESSION AP010958 SOURCE Escherichia coli O103:H2 str. 12009 DNA, complete genome. COMMENT locus start: 4707712; locus end: 4725980 FEATURES Location/Qualifiers source 1..18269 /organism="Escherichia coli O103:H2 str. 12009 DNA, complete genome." gene complement(0..587) /gene="mtlR" /locus_tag="mtlR" /db_xref="4707712..4708299" CDS complement(0..587) /gene="mtlR" /locus_tag="mtlR" /product="DNA-binding repressor MtlR" /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK" gene complement(587..1735) /gene="mtlD" /locus_tag="mtlD" /db_xref="4708299..4709447" CDS complement(587..1735) /gene="mtlD" /locus_tag="mtlD" /product="mannitol-1-phosphate dehydrogenase MtlD, NAD(P)-binding" /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH SYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHF RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ" gene complement(1830..3743) /gene="mtlA" /locus_tag="mtlA" /db_xref="4709542..4711455" CDS complement(1830..3743) /gene="mtlA" /locus_tag="mtlA" /product="fused mannitol-specific PTS enzymes: IIA component /IIB component/IIC component" /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL KTSKVKEEDDIEAATRRMQDMKAESKGTSPLSAGDVTNDLSHVRKIIVACDAGMGSSA MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT NFLDSGLYTSLTERLVAAQRHTENEVKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT SVDEVLELLAGRK" gene 4280..4642 /gene="yibI" /locus_tag="yibI" /db_xref="4711992..4712354" CDS 4280..4642 /gene="yibI" /locus_tag="yibI" /product="predicted inner membrane protein" /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL EHQLAAEKKTDYSTFPEI" gene 4645..5781 /gene="yibH" /locus_tag="yibH" /db_xref="4712357..4713493" CDS 4645..5781 /gene="yibH" /locus_tag="yibH" /product="conserved predicted protein" /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE QTVIRAPSNGYVTQVLIRPGTYAVALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH" gene complement(6240..6677) /gene="" /locus_tag="" /db_xref="4713952..4714389" CDS complement(6240..6677) /gene="" /locus_tag="" /product="conserved predicted protein" /translation="LADKAILWALISASTKEGRKACSLSYFACKAAEAELGLAYMAAN DNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIETVNK IKDKNKKIIDINSVNICSDDKNIKLRVNSTIMAIDDSIKCIDE" gene complement(7384..7845) /gene="yibG" /locus_tag="yibG" /db_xref="4715096..4715557" CDS complement(7384..7845) /gene="yibG" /locus_tag="yibG" /product="conserved predicted protein" /translation="MKACLLLFFYFSLIGQLHGADVKIKENESVMGSTAMTYDLSEEK LMKLKYKSQHGDSEASFRLYQYYCFTKNNIDKQLRFLERSASQGNVTAQFNYGVFLSD TNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP" gene complement(7857..8795) /gene="" /locus_tag="" /db_xref="4715569..4716507" CDS complement(7857..8795) /gene="" /locus_tag="" /product="" /translation="MLDRLESEILADRVSEESRRWLASCGLTVEQMKNQMDPVYTPAR KIHLYHCDHRGLPLALISTEGATAWCAEYDEWGNLLSDENPHHLQQLIRLPGQQYDEE SGLYYNRHRYYDPLQGRYITQDPIGLKGGWNFYQYPLNPVINVDPQGLVDINLYPESD LIHSVADEINIPGVFTIGGHGTPTSIESATRSIMTAKDLAYLIKFDGNYKDGMTVWLF SCNTGKGQNSFASQLAKELHTNVIGPDTLWTWWGRGTNGKLKMDTVLTAPTNLNSNKD LMAITTKDLGNWITYGPSGHPISNMQGTPEKPSDIR" gene complement(8843..9685) /gene="yibA" /locus_tag="yibA" /db_xref="4716555..4717397" CDS complement(8843..9685) /gene="yibA" /locus_tag="yibA" /product="lyase containing HEAT-repeat" /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA RVLQLRGGQDAVRLAIEFCSDKNYIRRDIGAFILGQIKICKKCEDNVFNILNNMTLND KSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAFDKSTNVRRATAFAISVINDKAT IPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEMLQDKNEEVRIEAIIRLSY RKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTMLYKFDDNEIITSAIDK LKRS" gene complement(9790..10173) /gene="" /locus_tag="" /db_xref="4717502..4717885" CDS complement(9790..10173) /gene="" /locus_tag="" /product="conserved predicted protein" /translation="MSAEFMVICKKILFRNCVIVSLFVFTYNTWAQCNNNIKIMRKYE SEGKYTVRNLVKNKAIALELAEIYVKNRYGQDAAEEEKPYEITELTTSWVVEGTIHSD QIAGGVFIIEIGKNDGRILNFGHGK" gene complement(10145..14314) /gene="rhsB" /locus_tag="rhsB" /db_xref="4717857..4722026" CDS complement(10145..14314) /gene="rhsB" /locus_tag="rhsB" /product="Rhs core protein with extension" /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT SGHPVNPLLGAKVLPGETDIALPAPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI RLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQ ALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGR TQTFHREAAGEFSGEITGVTDGAGRHFRLVLTTQAQRAEEARQQAISGGTEPSAFPDT LPGYTEYGRDNGIRLSAVWLTHDPEYPENLPAAPLVRYGRTPRGELAVVYDRSGKQVR SFTYDDKYRGRMVAHRHTGRPEIRYRYDSDGRVTEQLNPAGLSYTYQYEKDHITITDS LDRREVLHTQGEAGLKRVVKKEHADGSVTQSQFDAVGRLKAQTDAAGRTTEYSPDVVT GLITRITTPDGRASAFYYNHHSQLTSATGPDGLEMRRKYDEYGRLIQETAPDGDITRY RYDNPHSDLPCATDDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQVTAVHRE EGLSQYRAYDSRGQLIAVKDTQGHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAI CTTQGGLTRSMEYDAAGRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLT GKLIRSEDEGLVTHWHYDEADRLTHRTVKGETAERWRYDERGWLTDISHISEGHRVTV HYGYDEKGRLTGERQTVHHPQTEALLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYG SGWLSGMKLGDTPLVEYTRDRLHRETLRSFGRYELTTAYTPAGQLQSQHLNSLLSDRD YTWNDNGELIRISSPRQTRSYSYSTTGRLTSVHTTAANLDIRIPYATDPAGNRLPDPE LHPDSTLSMWPDNRIARDAHYLYRYDRHGRLTEKTDLIPEGVIRTDDERTHRYHYDSQ HRLVHYTRTQYAEPLVESRYLYDPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWD GDRLTTIQNDRSRIQTIYQPGSFTPLIRVETATGEQAKTQRRSLADTLQQSGGEDGGS VVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQNQMDPVYTPARKIHLY HCDHRGLPLALISTEGATAWCAEYDEWGNLLNEENPHQLQQLIRLQGRYITQDPIGLK GGWNLYGYQLNPISDIDPLGLSMWEDAKSGACTNGLCGTLSAMIGPDKFDSIDSTAYD ALNKINSQSICEDKEFAGLICKDNSGRYFSTAPNRGERKGSYPFNSPCPNGTEKVSAY HTHGADSHGEYWDEIFSGKDEKIVKSKDNNIKSFYLGTPSGNFKAIDNHGKEITNRKG LPNVCRVHGNM" gene complement(14474..14686) /gene="rpmE" /locus_tag="rpmE" /db_xref="4722186..4722398" CDS complement(14474..14686) /gene="rpmE" /locus_tag="rpmE" /product="50S ribosomal subunit protein L31" /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF TGKQRDVATGGRVDRFNKRFNIPGSK" gene 14889..17087 /gene="priA" /locus_tag="priA" /db_xref="4722601..4724799" CDS 14889..17087 /gene="priA" /locus_tag="priA" /product="primosome factor n'" /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF NDAALQALRKKGLCDLASETPEFSDWQTNYAVSGERLRLNTEQATAVGAIHSAADTFS AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL DLKGQKVQAGLAPALITRMRQHLQANNQVILFLNRRGFAPALLCHDCGWIAECPRCDH YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPDVPIS RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADDKLWVLGPVPALAPK RGGRWRWQILLQHPSRVRLQHIISGTLALINTIPDSRKVKWVLDVDPIEG" gene 17243..18268 /gene="cytR" /locus_tag="cytR" /db_xref="4724955..4725980" CDS 17243..18268 /gene="cytR" /locus_tag="cytR" /product="DNA-binding transcriptional dual regulator CytR" /translation="VKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR GSTRALP" ORIGIN 1 ttacttttga aaggcttttt ttaagctgat tctggaaatc agctcagtca gtgaaaggac 61 cattgttgat cgcacagcct gttgatagcg ctgaatttgc attgcataca aactggagtc 121 tgctggttca aactgtggcg gcggtggtaa cgccgccacg cagtgcagtt caccaaaggg 181 tccaaggatc tcgtcgtcgg taaaggcgta ctcgttgccg tcgtgattta gttcttcacg 241 caatgccatc agcagctccg catcttcgta ttcctggcgg ttaatgacgc ccaacccgta 301 aatgagtttt aaacgcacag aaagatcgcc cagcggaccg tcgccgtcga gtaacggttc 361 tacagcatac ttcaccgcgt aatcgtcttt gcggaatacc tgaagcacca gaagatttac 421 cgcctcggtc aaaagctcga cggcggtgat cagaaagctt cgcacggttt tgccagcatt 481 cagacgctca agcacacggt tttcaaaggc ctgggtttgt tccattgttg cctgcatatc 541 tgacaatctg ttattcgggc gcagggtgtc ctgcgcctgg tccaccatta ttgcattgct 601 ttataagcgg ttaccgcctc ggatacaacc tcgctgttgg catcaagacc ggaaatctgt 661 gccagcgccg cctgcggacc tttgtcagcg atcagtgctg ccagttcctg agcctgcgga 721 tcatcttcac tgcggaagtg cattgcacca gcaatcccct gaatcagatt cttgtgcgga 781 aggctgtatt ccagcgtacc gagcagtggc ttgatcagac ggtcgccagc actcagttta 841 cgcagcggct gacggcctac gcgctctaca tcatctttca gatacgggtt ctcaaaacga 901 ccgaggattt tctggatgta cgccgcatgt ttgtctgcgt caaagccgta gcgcttgatc 961 agtaccgcac cactttcttc catcgcacct tttaccaccg cgcggatttt ctcgtcgaga 1021 atagcgtcac gaatggtctg atgaccagcc agttttccga ggtacgcggt tatagcatga 1081 cccgtgttca gggtgaagag tttacgttcg acaaatgcca tcaggttgtc ggttaactcc 1141 atgcctggga tgttcggcag tgcgcctttg aactgcgttt tatcgacaat ccattcgctg 1201 aaagtttcta ccgtcacttc cagcggatcg ttagttgccg aagccgaagg cggtacgatg 1261 cggtcaacgg cggaatcgac aaagccaacg tgttcttcta cccacgcttt ggcgtcttcc 1321 ggcagggcgt tcatcacatg gcctttcagc tgcgtggtac cgcgtaccat gttttcacag 1381 gcgatgatgt tcagcgggga ttcattacct tgttctttac gtttcaccag ccctttggcg 1441 atagccggag caatacgttc cagcacaacc gggccaacgg cggtagtgac taaatcgacc 1501 tgagcaatca gatcaacgac atcatcacca atgctgctga cagcatcgac gccggaaacg 1561 gtatctacct gctcggtttc accaaccaca tgaacctgat agctatgacg ggcattcagg 1621 gcatcaagta ccacctgatt gacatcggca aacgtcagtt ggatacccgc gtctgccagc 1681 agtttaccga taaagccacg accgatatta cctgcgccaa aatgtaatgc tttcatagta 1741 ttaaccttca tcaatgtttt tacccgagag ggctggggtg aggcttttcc ctcacccaaa 1801 ccctctccgt gaggagaggg taggattgga ttacttacga cctgccaaca gttccagcac 1861 ttcatccacg ctggtggtgt gtgccagacg ctcgatgacg gactcatcat ccagtgcatt 1921 ggtcaggctg gtgataacct gaatgtgctc gttgttacgg gctgcaatac caatcaccag 1981 acgggcaatg tcatcttctt cttcaccgaa gcgcacgcct tccgggtact ggcagaacac 2041 cacgcccgtt ttcagtacgc gatctttcgc ttcaaccgta ccgtgtggca ccgcgataga 2101 ctcacccaga taagtcgggg tcagtttttc acgatccagc atcgcctgaa cgtattccgg 2161 ctcaacgtaa ccgcctttca ccagctgctc gccagcaaaa cgaatcgctt cttctttggt 2221 tgctgctttg cgaccgagga agatgttctc cgcgcccagt ttgaacaggt tagcactgga 2281 atcgtcaaag ctgtctttca gactgtcttt cactttcact tcgttttcag tatggcgctg 2341 ggcagcaacc agacgttcgg ttaggctggt gtacaggccg ctgtcgagga agttggtcag 2401 cgaaatatgc tgcgcctgcg gaacctggcg catagcgcgt tcggtcaggt cacggtgagt 2461 gatgacgagg tccacatctg gcggcaggtt gttgatcgcg ctgttagtga ccgaaatctg 2521 tgacagacct gcatcctgaa ttttcttacg cagcacgcct gcgcccatcg cactggaacc 2581 cataccggcg tcacaggcaa cgatgatttt acgtacgtgg ctcaggtcgt tagtcacatc 2641 gcccgcagac agcggagatg tgcctttaga ctcagctttc atgtcctgca tacgacgagt 2701 tgctgcttca atatcatctt cttctttcac tttgctggtt ttcagcaaaa tagcagagac 2761 aacgaaggag acagccatcg ccgcacacac acccgcgatg ttagcgaaat aagcaccttt 2821 tggtgtcatc gccagtacag caaggataga acccggagat gccggagaaa ccagaccacc 2881 gcccaggata gtcagcgtga acacgccagt cataccgccg aggatgactg cgaggatcag 2941 acgcggattc atcagcacat acgggaagta gatttcgtgg atacccccca ggaagtggat 3001 gattgccgca ccgcccgcag actgtttagc gctaccacga ccaaagaaca tgtacgccag 3061 cagcacgccc atacctggac ctgggttagc ttcaatcagg aagaagattg atttacccag 3121 ttcatgggac tgctgaatac ccagcggcga gaagataccg tggttaatgg cgttgttgag 3181 gaacaggatt ttcgccggtt caacaaagat agacgccagc ggcagcatgt catggacaac 3241 catgaagtta acgcccgcag ccagcatttt ggacagggct tcaacaatcg ggccaatgcc 3301 gaggaatgcc agaatagcga ggatcatccc gatgatgcct gcggagaagt tattcaccag 3361 catctcaaaa ccggatttga tcttaccgtc tacccagcgg tcgaagtgct taatgcacca 3421 gccgcccaga ggacctgcaa tcatagaacc gaggaacatc ggcatgtctg cgccgacgat 3481 aacgcccatg gtggtgatgg caccgactac gccgccacgt tcgccgccta ccagcttacc 3541 accggtataa ccgatcagca gcggcaggag ataagtgatc atcggcccga ccagcttcgc 3601 cagcgtctcg ttcggtaacc accctgttgg aataaataac gcggtgatga taccccacgc 3661 gataaacgcg ccgatatttg gcatcaccat gttgctgagg aaacgaccaa agctttgcac 3721 tttgatctta atatcggatg acataaaaac accccttctt atgtttgctg tcgcgcaggc 3781 tggaagcccg aggttttttg ttaatgtggc ggcagaggta gccggacctt gtagatactg 3841 cgaaatctgg cactgaatcg gttaactgtc cagtcgacgg ccttttgtgt gatatcaatc 3901 acataaatat agggggtaga gaggtaattg acgtgacgtt catcacaaaa cgcttgtgta 3961 aaaaagcaac aaggcggcga ttttcgctaa aaatggcatt taaatgtgag tagtgtcaca 4021 tttttgtttt gatggtttgt tgaatctttg tgatctgaat cacaagatat tttcttacgg 4081 cgttcacctg atgtgatcta cagcatgtta tgccttcgtc atacaatcgt tatgtaacta 4141 agcaactcat cacctctaaa aattattctt tggtgttatg gcgagaatcg cgaacccgga 4201 ttattgtcaa aatatcagcc tgactccctt ctggctgcca gcccaaaaac aacactgata 4261 aacgtgaatc cgaggcagat atgtttctaa actatttcgc gttgggagtg ctgatcttcg 4321 tctttctggt gattttttat ggaatcatcg cgatacatga catcccttat ctgattgcca 4381 aaaagcgcaa ccatccccat gccgacgcta ttcatacggc gggctgggtg agcctgttta 4441 ctctgcatgt tatctggccg tttctgtgga tctgggcgac gctctatcaa ccggagcgtg 4501 gctggggtat gcagtcacat gttgcgtcgc aggagaaagc gactgacccg gaaatcgccg 4561 cactttctga ccgaatttcc cggctggagc atcaactcgc cgccgagaaa aagactgact 4621 attccacgtt cccggagatc taattatgga tctattgatt gttttaactt acgtggcgct 4681 ggcgtgggcg gtctttaaaa tcttccgcat tccggtaaat cagtggacgc tggcgacggc 4741 ggcgctggga ggcgtgtttc tggtgagtgg tttgattttg ttgatgaact acaaccaccc 4801 ttacactttt accgcgcaaa aggcagtgat agcgatccct atcacgccac aggtgacggg 4861 aattgttact gaagtcactg acaagaataa tcagcttatt caaaagggcg aggtgctttt 4921 taagctcgac ccggttcgtt accaggcgcg agttgacaga cttcaggctg acctgatgac 4981 ggcgacgcat aatataaaga cgctgcgtgc gcagctcact gaagcgcagg ccaacaccac 5041 ccaggtttca gcggagcgcg accgtctgtt taaaaattat caacgttact tgaaaggcag 5101 ccaggcggcg gtgaatccgt tctcggaacg tgacatcgac gatgcgcggc aaaatttcct 5161 cgcgcaggat gcgctggtga aaggctcggt ggcggagcag gcgcagatcc agagccagct 5221 cgacagtatg gttaacggcg agcaatcgca gattgtgagc ttaagagcgc aacttactga 5281 agcaaaatat aaccttgagc agactgtcat tcgcgcgccg agcaatggct acgttactca 5341 ggtactgatc cgcccaggta catacgcagt tgccttgccg ctgcgtccgg tgatggtctt 5401 catccccgag caaaaacggc aaattgtcgc ccaatttcgg caaaactcgc tgttacgtct 5461 gaaacccggc gatgatgcgg aagtggtgtt taacgcgcta cctgggcagg tgtttcacgg 5521 caaactgact agtattttac ctgtcgtgcc aggcggttct tatcaggcgc agggggtatt 5581 gcaatcatta acggtcgtgc ccggcacgga cggtgtgctg ggaaccattg aactggaccc 5641 taacgatgat atcgatgcct tacccgacgg catctacgcc caggtggcgg tttactccga 5701 ccatttcagc catgtttcgg tgatgcggaa agtgctgcta agaatgacca gctggatgca 5761 ttatctttat ttggatcatt gagggggagg ggggagatta tggaactttg ctccttgtaa 5821 ggactaatta tttttgcata ttacttcatt agctgcgatg atttttcttt aatattcatt 5881 atgttaataa gttctggatg agtgtgctct cattggattt tttatccgtc ttgttctgcc 5941 gcaggatgag actatacatc gtcgagatcg caatgatgat atgagttgtt cctcctgcga 6001 cggctctaat caaaaaagag caggagtgct tttccatcta ttgcgatgat ggctttatta 6061 tctgaaggat gacagtcaca tttaaaaaat atttaatcta tagatcacaa tgtagggtca 6121 tggaatatat gtatacaact attttcttct tcacttttaa ttatcgtatt cattataaaa 6181 ctaagttaaa aaactcctgg agagtgtgtt attaatatat ttttaaataa aattaagtta 6241 tcattcatcg atgcacttta tagaatcatc aatggccata atagtactat taactctcaa 6301 ttttatattt ttatcatcac tgcaaatatt aactgaattt atatcaatga tttttttatt 6361 cttatctttt attttattta ctgtttcaat gcaatcagcg gcaagttgga gtggatttag 6421 atttttcaga tatggtctta tgatctttcc cttacttaat aaatagcatg tataggattc 6481 ggaaagtcca gcatctattt tgtacctcat tatattagat aaggatgtga gaaattcctt 6541 gttatcattc gcagccatat atgccagtcc gagttcagcc tctgcggcct tacaggcaaa 6601 atagcttagt gaacacgctt ttcgtccctc tttagtactg gctgatatta gtgcccataa 6661 tattgctttg tctgccaaat ctaactctct ctgaaattgt cttgcagtaa ctgcactcgc 6721 agaaatagag aaaaaaatac aattgttaat aaccttgcca tattttttag tccgtaactg 6781 ttaatgtgct atctggctct gaaaatatta actcatttaa tttttgcatg tcattagata 6841 aaccagttat acaaccctcg gaacagaatc gaggtcctaa agacggacca aaagcgttta 6901 aacaactatg tattgaaaat ccattgcgat tataagttcc tgtattaact gacggtacta 6961 atcgtatgcc gtcaggtttt ctattgcttg ctcccgggtc attaacattc taactccata 7021 ggccttgagg tattggccat ctatttataa atgtgtacaa cggggattat ttttacattg 7081 catattatta ccagaagcga ctggaatact aagcacatca taaaaattat catcacatgg 7141 tatatctgaa acacacgaaa gcatacctaa agttatactg tataaacagg tggctaatcc 7201 caaggggatc gattccagaa atcgggttca acggatactg ataaaaattc cacctacctt 7261 ccagcccaat cggagcctga gtgttatacc gcccctgctg cggttaatgt taccgataat 7321 agttatagta cagccctgat tcatcatcat actactgctg cggcagtctg atgaactatt 7381 gcttttacgg attctcctta ttcttccttc tatccattcg ctttagcttt ttgagctctt 7441 gaagtttgct ctttgcatca atattaccgt tatttacagc gaattccatc caataaatag 7501 ctctattcaa attataatat tctgataatg ttggatttgt atctgataaa aagaccccat 7561 aattaaactg cgctgtaaca ttcccctgag atgctgatct ttccaagaat cgcaattgtt 7621 tatcaatatt atttttagta aagcagtaat attgatatag tcgaaatgat gcctctgaat 7681 caccatgttg tgatttatac ttcagtttca tcagcttttc ttcacttaaa tcataggtca 7741 ttgctgtaga tcccatcaca ctttcgtttt cttttatttt cacatcagca ccatgcaatt 7801 gaccaataag agaaaaataa aaaaatagta acaagcatgc tttcatacat ctacaaccta 7861 tcttatatca ctgggttttt ctggcgtacc ttgcatatta gaaatggggt gcccagatgg 7921 cccatatgtt atccaattac caaggtcttt tgttgttata gccattagat ccttatttga 7981 attaaggttc gttggtgctg ttagcactgt atccattttt aacttaccat tagttcctcg 8041 cccccaccac gtccatagcg tgtcaggtcc tattacattt gtatgtaact ctttagctaa 8101 ttggctagca aatgaatttt gtcctttacc tgtattacaa gaaaataacc aaactgtcat 8161 cccatcttta taattcccat caaatttaat tagatatgct agatctttag ctgtcatgat 8221 actgcgcgtt gcggattcaa tagatgtggg ggtaccatgc cccccgattg tgaaaacgcc 8281 tgggatatta atctcatcag ctacagaatg gataagatca ctttcggggt ataaatttat 8341 atcaaccaaa ccttgcggat ctacatttat gaccggattc aacggatact gataaaaatt 8401 ccatcccccc ttcagcccaa tcggatcctg agtgatatac cgcccctgca gcgggtcata 8461 atagcggtgg cggttgtaat acaggccgga ctcctcatca tactgctgac ccggcaggcg 8521 aatgagctgc tgcagatgat gcgggttctc atcactcagc aggttgcccc attcatcata 8581 ttctgcgcac cacgctgttg ccccttccgt gctgatgagc gccagcggca ggccgcgatg 8641 gtcgcagtgg tacaggtgga tttttcgcgc cggcgtgtac accgggtcca tctggttttt 8701 catctgctcc acggtcaggc cgcacgatgc cagccagcgg cggctttcct cactcacccg 8761 gtcagccagg atttcacttt ccagccggtc gagcatctgc accgtgccgg cgggaatccc 8821 ccactgtgca taggcaactc acgctatgaa cgcttcagct tatcaatagc ggaagttata 8881 atttcattgt catcaaactt gtacaacata gtatctaaaa caggaagtag cgttttatca 8941 cctaattcac ccgcagcttc aatgatatca tcataaacag tatttttttt taactcatcg 9001 cataaaacag ataaaaccct tttatctttt ctgtaggaaa gtctgattat tgcttcaata 9061 cggacttcct catttttatc ctgaagcatc tccacaaaac aatccctaat atcactatta 9121 tcatatttat tgatatttat tgcaaatgcg gcccagtttc tgacatctcc atttggatct 9181 tttaacagat taatcaatag tggaattgtt gctttatcat tgataacaga aatagcaaat 9241 gctgtagcac gtctgacatt agtcgattta tcaaaagcag taatttgaga ttgttctact 9301 attttaggtg aataaattgg gtttttcttg catcgctgag ccgttgactc gattgccgta 9361 gctcgaacgc aagcgctctt atcattcaat gtcatattgt tcaaaatatt aaaaacatta 9421 tcttcgcatt ttttgcaaat ttttatttgc ccgagtataa atgctccgat atctctacgg 9481 atataatttt tatcagagca gaactcaatt gccaatctaa cagcgtcttg cccacctctt 9541 aactgtaata ctctggcaga tgaaatcctt ttcaaggaat tgtgatcatc aagtaagcga 9601 aataattcat catcatttag tttcttacat tgattatata aaccatactc tttacttgcc 9661 tttcttttct ggtatgtatt tgacattgca ggaacctcca taaaggctat ctttttctat 9721 cgtttgactg tctggagtcc tccacctact ctgccatcag cgcacacgat gtttgattat 9781 ccttacatac ttattttccg tggccaaaat tcagaattct cccatcattt ttgcctattt 9841 ctataataaa aaccccacca gcaatttggt ctgagtgaat ggtaccttca acaacccaac 9901 ttgttgttaa ctcagtgatt tcgtatggtt tttcttcttc tgcggcatcc tgtccataac 9961 gattcttaac atatatctca gctaattcca atgctatagc tttattttta accaaatttc 10021 taacggtata tttaccttca ctttcatact tgcgcattat tttaatatta ttattacact 10081 gcgcccatgt gttgtatgta aaaacaaaca aagatacaat gacacagttc ctaaacaata 10141 tttttttaca tattaccatg aactctgcag acattaggta atccttttct gtttgttatt 10201 tccttcccgt ggttatctat tgctttaaaa ttaccactgg gcgtacctaa ataaaatgac 10261 ttgatattgt tatctttact tttaactatt ttctcatctt tacctgaaaa tatttcgtcc 10321 caatattctc catgactatc tgcaccatga gtatgataag ctgatacttt ctcagtacca 10381 ttagggcaag ggctattgaa tggatatgat ccttttcttt ctcctcggtt aggtgctgtt 10441 gagaaatatc tgccactatt atccttacat attaaaccag cgaactcttt atcttcgcaa 10501 atagattggc tatttatttt atttaaggcg tcatatgcgg tgctatctat agaatcaaat 10561 ttatctggac ctatcatagc ggatagtgtg ccgcaaagac cattagtaca tgcccccgat 10621 tttgcatcct cccacataga taaacccagg gggtcgatgt ctgatatcgg attcaattga 10681 tatccataca ggttccatcc ccccttcagt ccaatcggat cctgagtgat atatcgcccc 10741 tgcagccgga taagctgctg cagctgatgc gggttctctt cattcagcag gttgccccat 10801 tcatcatatt ctgcgcacca cgctgttgcc ccttccgtgc tgatgagcgc cagcggcagg 10861 ccgcgatggt cgcagtggta caggtggatt tttcgcgccg gcgtgtacac cgggtccatc 10921 tggttttgca tctgctccac ggtcaggccg cacgatgcca gccagcggcg gctttcctca 10981 ctcacccggt cagccaggat ttcactttcc agccggtcga gcatctgcac cagcaccggc 11041 gggaacacca cactgccacc gtcttcgccg ccggactgct gaagggtatc cgccaggctg 11101 cggcgctgcg ttttcgcctg ctcaccggtg gcggtttcaa ccctgatgag tggcgtgaag 11161 ctccccggct gataaatcgt ctggatgcgg ctcctgtcgt tctgtatcgt ggtcagccgg 11221 tcgccgtccc agccgtacca ggtcacttgc ggtttccgtg acagcgacat ccagcccgtc 11281 aggtcccgtt cacgccgcca cacccgtttt gccaccctgc ggcccagcgg gtcgtaaaga 11341 tagcgacttt cgaccagcgg ctctgcatat tgtgtccgcg tgtagtgcac cagccggtgc 11401 tgactgtcgt aatggtaccg gtgagtccgc tcatcatccg tgcggataac cccttccggg 11461 atgaggtcgg ttttctctgt cagcctgccg tgacggtcat accggtaaag atagtgcgcg 11521 tcacgggcga tacggttatc cggccacatg ctgagggtgc tgtccgggtg cagctccggg 11581 tcgggcaggc ggttacctgc cgggtctgtg gcatacggga tgcggatatc cagattcgct 11641 gcggtggtgt gaacgctggt cagcctgccg gtggtgctgt agctgtaact ccgggtctgg 11701 cgcgggctgc tgatgcggat gagttcgccg ttgtcgttcc aggtgtaatc gcggtcagac 11761 agcaggctgt tcaggtgctg gctctgtaac tgcccggcag gggtgtaagc ggtggtgagt 11821 tcataacggc cgaagctgcg cagcgtttcc cggtgcaggc ggtcgcgggt gtactccacc 11881 agcggtgtgt cgccgagttt catgcctgac agccagccgc tgccgtaggt cagccattcc 11941 acggcgggca ggctgtccgg tatacagcgg ttcgccagcc cctgcgcgtt gtacgcatgt 12001 ctggtctcat gctgccagag cagtgcttcc gtctgcgggt gatgcaccgt ctgacgctca 12061 ccggtcaggc ggcctttctc atcatacccg taatgcaccg tcacccggtg cccttcgctg 12121 atatggctga tgtctgtcag ccagccgcgt tcgtcgtacc gccaccgctc tgcggtttca 12181 cccttcacgg tgcggtgcgt gaggcggtct gcttcgtcat agtgccagtg ggtgaccagc 12241 ccctcatcct cgctgcggat aagtttgccg gtcaggtcgt ggtgataacg ctgtgtgcgg 12301 ccgtcaaagc cggtttcctg tatcagccgg tcgagtacat cgtaacggaa ggtggtgtgg 12361 ctgccgtttt cactggtcag gcggatgacc cgtccggcag catcgtattc catactgcgc 12421 gtcagaccgc cctgcgtggt acagatggct tttccccacg catcgtactg tgtcccgttt 12481 ctgctgccgt ccggggcaat gacggtggtc aggtcaccgg cggcgttgta ttcataccgc 12541 gtttcatggc cctgcgtgtc tttcacggca attaactgtc cacggctgtc gtatgcgcgg 12601 tactgactca gcccttcctc gcggtgcacc gccgtcacct gaccaaaacg gtcatggtca 12661 tagcgggtta cataaccgga acagtcagtg aagctcagca actgaccgta acggctccac 12721 gtcatggttt tccggctgcc ggtggcatcg tccgttgcgc aggggaggtc actgtgtgga 12781 ttatcataac ggtagcgggt gatatcgccg tcaggggcgg tttcctgaat cagacgtccg 12841 tactcatcat atttgcggcg catttccagc ccgtctggcc cggtggctga cgttaactgg 12901 ctgtggtggt tatagtaaaa cgccgatgcc ctgccatccg gcgtggtgat gcgcgtgatg 12961 aggcccgtca ccacatccgg gctgtactct gttgtccggc ctgcggcatc cgtctgtgcc 13021 ttaagcctgc ccaccgcatc aaactgactc tgcgtgacgc tgccgtccgc gtgttccttt 13081 ttcaccaccc gcttcagccc ggcttcgccc tgcgtgtgca gcacttcacg gcggtccagg 13141 ctgtcggtga tggtgatgtg gtctttctca tactgatacg tgtagcttaa gcctgccggg 13201 ttaagctgtt ctgtcacccg cccgtcgctg tcgtaacggt aacggatttc cggccggccc 13261 gtgtgacggt gcgccaccat ccggccccgg tatttatcat cgtaagtaaa gctgcgcacc 13321 tgtttgccac tacggtcata caccaccgcc agttcgccgc gtggcgtccg gccatagcgc 13381 accagcggcg cggcaggtaa attctccggg tattccgggt cgtgcgtcag ccacacggca 13441 gacagacgga tgccgttgtc ccggccatat tcggtgtaac ccggcagggt atcaggaaaa 13501 gcggacggtt ccgtcccgcc ggaaatggcc tgctgccggg cttcttctgc ccgctgcgcc 13561 tgcgtggtca gtaccagccg gaagtgacgc ccggcaccat ccgtcacgcc ggtgatttcg 13621 ccgctgaatt caccggcggc ttcgcggtgg aacgtctgtg tgcgcccgaa gcggtccacc 13681 agcccggtca gtacccggta cggcggcagc ggcgcaggca gcacctcatc cgcttccggc 13741 acccgctcac accagccgag cagccaccac ggcccctgcg gactgtttgt cgccagataa 13801 cgatgcggac ttaagcggag ttcttccggc agcgcctgcc agagtgcggc cagccggtga 13861 ccttcatcca gtttcgccac gccgccgcgc accagccaca gtgactcgct gcggctgtaa 13921 ccgtcctcac cgggaaacag gtgctcaaaa tacaggcttc tgccgccgtt atcactgagt 13981 atcagtgtgt tatcgcgcag ctgtaagcgg atatccgcag gcattttcca gccggggccg 14041 aggctcccca ccggcgcggg cgtttttgtc cggtaactgc tgtaggtgcg ggagaggatg 14101 aacggcagcg gggcgggcag ggcgatgtcg gtttcaccgg gaaggacctt tgcaccgagc 14161 agcggattga ccggatggcc ggacgtcacc ccgccggggc acaccgaaca ggccacgccg 14221 gtgggggcac cgatgcgcac cccggctgaa ccctggacaa tgctaccgcc atactgcgtc 14281 atgtcgccct gacgcgccgc cggttttccg ctcatcgtaa aatccttttg aaataaataa 14341 gaaccagaag cctagcgcca gtcaacaaca ggaaatgata atgagttaac accccggaat 14401 ttttcagaat ttataaaagg caaattacag gcacaaaaaa agcgccgtgc ggcgcttttt 14461 tcggaaatcc ggtcttattt gctgcccggg atgttgaaac gcttgttgaa gcggtcaaca 14521 cggccaccgg tagcaacatc acgctgtttg ccagtgaaga acgggtggca cttgctgcac 14581 acgtcgaggt tcaggtcatg accaacggtg gagcggattt tcattacgtt accgcaagag 14641 cagctagcag taatttcttc gtatttcggg tgaatatctt ttttcatggg aaaacctcgg 14701 tttaaggccg cgtcgctctt ccagccctaa cgccagacac cacgcgatgt taaaagtata 14761 gcttcaatac gatcatttcg tacgaaggcg cgaaatcata cagaaattaa ccagcgtatg 14821 caaactgatc cgcactcttc tacggcaatg tgtatactaa cccaccgaat ttcaagtcag 14881 gatgatgcta tgcccgttgc ccacgttgcc ttgcccgttc cgcttcctcg tacctttgac 14941 tatctgctgc cagaaggcat gacggttaaa gccgggtgtc gcgtgcgcgt gccgtttggc 15001 aaacagcagg agcgcatcgg ggttgtggtg tcagttagcg atgtcagtga gctgccgctt 15061 aacgagctga aagcggtagt ggaagtgctg gacgttgagc cggtatttac tcactccgtc 15121 tggcggttac tgctctgggc ggcagattac tatcatcatc cgattggcga tgtgctgttt 15181 catgccttgc cgattttact gcgccagggg cggcctgcgg cgaacgcgcc gatgtggtac 15241 tggtttgcca ctgaacaagg ccaggcggtg gatctgaaca gcctgaaacg ctcccccaag 15301 caacaacagg cgctggcggc gttacggcaa ggcaaaatct ggcgcgacca ggtcgccacg 15361 ctcgaattta atgatgccgc gttgcaggcg ctacgcaaaa aaggtctgtg tgatttagca 15421 agtgaaacac cagagtttag cgactggcaa acgaactatg ccgtttctgg tgagcggttg 15481 cgattgaata ccgaacaggc caccgccgtt ggcgcaattc atagcgcggc agatactttt 15541 tctgcctggc tgctggcggg cgttaccggt tccggtaaaa cggaggttta tctcagtgta 15601 ctggaaaacg tgctcgctca gggcaaacag gcgctggtga tggtgccgga aatcggcctg 15661 acaccgcaaa ctatcgcccg ttttcgtgaa cgttttaatg cccccgtgga agttctgcat 15721 tccggcctga acgacagcga gcggctttcg gcgtggttga aagcgaaaaa tggcgaggcg 15781 gcgattgtga tcggcacccg ctccgcgctg tttacgccgt ttaaaaatct cggcgtgatt 15841 gtcattgatg aagagcacga cagctcctac aagcagcagg aaggctggcg ctatcatgcc 15901 cgcgacctgg cggtgtatcg tgcgcatagc gagcaaatcc cgattattct tggctccgca 15961 acgcccgcgc tggaaacgtt gtgcaacgtc cagcagaaaa aataccgcct gctgcgcctg 16021 acgcgccggg cggggaatgc gcgtccggca attcaacacg tgctggattt aaaaggtcag 16081 aaggtgcagg caggtctggc tccggcgtta atcacccgta tgcgccagca tttacaggcc 16141 aacaatcagg ttatcctctt tcttaatcgt cggggttttg cgcctgcgct actgtgccac 16201 gactgcggct ggattgccga atgcccacgt tgcgatcact actacacgct gcatcaggcg 16261 caacagcatt tgcgctgtca ccactgtgac agtcagcgtc cggtgccgcg ccagtgccct 16321 tcctgcggtt ccacgcacct ggtacccgtg gggctgggca ccgaacagct tgaacagacg 16381 cttgcgccgc tgttccctga tgtgcccatt tctcgtatcg accgcgatac caccagccgc 16441 aaaggggcgc tggaacagca actggcggaa gtacatcgcg gcggtgcgag gattttgatc 16501 ggcacacaaa tgctggcgaa aggtcaccac tttccggatg tgacgctggt ggcgttactg 16561 gatgtggacg gcgcgctgtt ttctgccgat tttcgctcgg cagagcgttt cgctcagctt 16621 tacacccagg tcgctggtcg tgccgggcgt gcgggtaaac aaggcgaagt ggtgctgcaa 16681 acgcaccatc cagaacatcc tctgttgcaa acgttgctct ataaaggcta cgacgccttt 16741 gccgaacagg cgctggctga gcgacggatg atgcaactgc cgccatggac cagccatgtg 16801 attgtgcgtg cggaagatca taacaatcag catgcgccgc tgttcctgca acaactgcgt 16861 aatctgatcc tctccagccc gctggcagac gacaaactgt gggttctcgg tccggttccg 16921 gcactggcac ctaaacgtgg cggtcgctgg cgctggcaga tattgttgca gcacccttcc 16981 cgcgtgcgct tgcaacacat cattagtggt acgctggcgc tcatcaatac aataccggat 17041 tcccgcaagg tgaaatgggt actggatgtt gatccgattg agggttaaac cgcttacgat 17101 gcgaggcgga tcgaaaaatt caatattcat cacacttttc atgaaaattc tgtaaccgtt 17161 ttcacgcgct atctgctaaa aatgttgccg atgtgaagta aacatggatg tagtacgcct 17221 gacgtgccag gcgaggagtg agtgtgaaag cgaagaagca ggaaactgcc gcgaccatga 17281 aagacgttgc cctcaaggca aaagtctcta cagcgactgt ctcccgagca ttaatgaatc 17341 ccgataaagt ctcccaggcc acccgtaatc gggttgaaaa agcggcccgg gaagtgggtt 17401 atttaccgca gcctatgggg cgcaacgtca agcgtaatga atcccgcacc attctggtga 17461 ttgtcccgga tatctgcgat cccttcttta gcgaaattat tcgcggtatc gaagttacgg 17521 cggcaaatca cggatatctg gtgctgattg gcgactgtgc gcatcaaaat cagcaggaaa 17581 aaacctttat cgatttgatc atcaccaagc aaattgatgg catgttgctg ctgggttcaa 17641 ggctgccgtt tgatgccagc attgaggaac agcgtaatct gccgccgatg gtgatggcga 17701 acgaattcgc accggaactg gagctaccta cagttcatat cgacaatctg accgccgcat 17761 ttgatgcagt aaattatcta tatgagcaag ggcataaacg gattggctgt atagccggtc 17821 ccgaagagat gccgctgtgt cactaccgcc tgcaaggtta cgttcaggcg ctgcgtcgct 17881 gcggcattat ggttgatccg caatacatcg cccgtggcga cttcaccttc gaagccggaa 17941 gcaaagcgat gcagcagctg cttgatcttc cacaaccgcc tactgctgtc ttctgccata 18001 gcgatgtgat ggcgctcggc gcactttctc aggcaaaacg ccaggggctg aaagtcccgg 18061 aagacctttc cataatcggt tttgataaca tcgacctgac gcaattttgt gatccgccgc 18121 tgacaaccat cgcgcagccg cgttacgaaa tcggtcggga agctatgctg ttattgcttg 18181 atcaaatgca ggggcaacac gttggcagtg gctctcgttt aatggactgc gaacttatca 18241 tccggggatc aacacgcgcg ttaccttaa //