LOCUS AP010958:10 18135 bp DNA linear BCT 27-AUG-2011 DEFINITION Escherichia coli O103:H2 str. 12009 DNA, complete genome. ACCESSION AP010958 SOURCE Escherichia coli O103:H2 str. 12009 DNA, complete genome. COMMENT locus start: 2134556; locus end: 2152690 FEATURES Location/Qualifiers source 1..18135 /organism="Escherichia coli O103:H2 str. 12009 DNA, complete genome." gene complement(0..611) /gene="ruvA" /locus_tag="ruvA" /db_xref="2134556..2135167" CDS complement(0..611) /gene="ruvA" /locus_tag="ruvA" /product="component of RuvABC resolvasome, regulatory subunit RuvA" /translation="VIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL" gene 886..1350 /gene="" /locus_tag="" /db_xref="2135442..2135906" CDS 886..1350 /gene="" /locus_tag="" /product="" /translation="VNINYPAEYEIGDIVFTCIGAALFGQISAASNCWSNHVGIIIGH NGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTEQQKQRIVEQVPSRLR KLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTF" gene complement(1490..2011) /gene="ruvC" /locus_tag="ruvC" /db_xref="2136046..2136567" CDS complement(1490..2011) /gene="ruvC" /locus_tag="ruvC" /product="endonuclease RuvC" /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM SESRLNLARGRLR" gene complement(2046..2786) /gene="yebC" /locus_tag="yebC" /db_xref="2136602..2137342" CDS complement(2046..2786) /gene="yebC" /locus_tag="yebC" /product="conserved predicted protein" /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD ANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR LIDMLEDCDDVQEVYHNGEISDEVAATL" gene complement(2815..3267) /gene="nudB" /locus_tag="nudB" /db_xref="2137371..2137823" CDS complement(2815..3267) /gene="nudB" /locus_tag="nudB" /product="dATP pyrophosphohydrolase" /translation="VEDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA" gene complement(3385..5157) /gene="aspS" /locus_tag="aspS" /db_xref="2137941..2139713" CDS complement(3385..5157) /gene="aspS" /locus_tag="aspS" /product="aspartyl-tRNA synthetase" /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMI FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE APSFANPTALAELSIQVVKKAENN" gene 5467..6033 /gene="yecD" /locus_tag="yecD" /db_xref="2140023..2140589" CDS 5467..6033 /gene="yecD" /locus_tag="yecD" /product="predicted hydrolase" /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS AEQHNNSINHIYPRIARVRSVEEILHAL" gene 6387..6635 /gene="" /locus_tag="" /db_xref="2140943..2141191" CDS 6387..6635 /gene="" /locus_tag="" /product="putative DNA damage-inducible protein" /translation="MRIEICIAKEKMTKMPTGAVDALKDELTRRISKRYDDVEVIIKA TSNDALSVTRITDKDSAKTFVQETLKDTWESADEWFVH" gene complement(6881..7471) /gene="" /locus_tag="" /db_xref="2141437..2142027" CDS complement(6881..7471) /gene="" /locus_tag="" /product="T3SS secreted effector EspM-like protein" /translation="MPMKTTGTSFSSFGVSCHRENSFRNPFRGKNDEVIKCSIGERTI RFSVDKFSGNILDTVRRQSAKNIDGWVKDEQMVYPSRVINQEIDNYCLQRNEKITTEV KQRVFSLVSQKYQLSLDIKAAQSSINHVIMGNASFGKKIDALCDGMSRDVKNRTSDSI ANLLADKFYQKHIDSDIDIVKLRNEIPDYLRFAIQA" gene 7655..8305 /gene="" /locus_tag="" /db_xref="2142211..2142861" CDS 7655..8305 /gene="" /locus_tag="" /product="T3SS secreted effector NleG-like protein" /translation="MPVILNFSNGSVLPENELEALRHIARSNQNDTITIGSRNMRLHY IQFMDGFSVEPIPGGLRDRLGARETHHLADSLTRQLNGGNTFLQAYSLYLEQRHAAPL VQESVIKTLLDRINLNAFPVSLQDFSCTEEYLNCPITLHIPETGVFVRNALSSEICAL YDQKALTELIRRNALHPFSREPFSPEMIIRKETCHFNIAKQCFCAFPIYPLQQNSI" gene 8384..9442 /gene="" /locus_tag="" /db_xref="2142940..2143998" CDS 8384..9442 /gene="" /locus_tag="" /product="T3SS secreted effector EspW-like protein" /translation="MPKISSVVSSCYYLFREHQQLSNETTMTNSASRRIVHKEHGISL KSVPVWLATAKTPLALLNGKHTRSHSFIIAGTPGMGGRSGAQYYAINSDDKRSRIDID SLFLKKLNNARNQNKFSIDVKETVIKLQGQKFTCIEDFHKKYSEIRLKTNSNIQQKQI TDEVKSLTYLIPSEKKEMWIYKNNGKDNAKPNLGERDVRMFENISPDDTDKITGRKFS ELGEYLYSGNVIKLSQLSIRYLPNINSISLIETKQSLLLHRLYSDEVLQRNGTLIPTP LHEEKSIPAANIKTMLNNIPTYKMLPPFTETQGNCSSGAATFLRKSGAEEKDILACSP RNYGLHHNIKTWDPLVRN" gene complement(9570..10205) /gene="" /locus_tag="" /db_xref="2144126..2144761" CDS complement(9570..10205) /gene="" /locus_tag="" /product="T3SS secreted effector NleG-like protein" /translation="MPVTTLSIPSISQLSPAGVQSLQDAARLESGIRISIGSGQYSVH YVQLLDGFSVEPVRGGLLDRLLGREHRMERRAVALERQLNGGVDFLSSVNNYFQSVMA EHRENKTSNKILMEKINSCVFRPDSNHFSCPESFLTCPITLDTPENGVFMRNSRGAEI CSLYDKDALVQLVETGGAHPLSREPITESMIMRKDECHFDSKKEAFVASDA" gene complement(10284..10856) /gene="" /locus_tag="" /db_xref="2144840..2145412" CDS complement(10284..10856) /gene="" /locus_tag="" /product="T3SS secreted effector NleG-like protein" /translation="MPGLVSYISSTSFANEMAEMRQQVMEGQIGGFLLGGERVRVSYI LDTGRFLAESEGLGVVYAELLNIVFNDGVDALRNRMLSVLPGMAAQRQENSLQAKISE CTFTVDIEKLHCTGEVLQCPITLEQPEKGIFVKNSDGSDVCTLFDAAAFSRLTGEGLP HPLTREPITASIIVKHEECAFMTIPEETSL" gene complement(10967..11236) /gene="" /locus_tag="" /db_xref="2145523..2145792" CDS complement(10967..11236) /gene="" /locus_tag="" /product="conserved predicted protein" /translation="MNVLKKLMQRLCGCGKHDDREHGELLTAQLRLGPADILESDENG IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK" gene complement(11238..12551) /gene="" /locus_tag="" /db_xref="2145794..2147107" CDS complement(11238..12551) /gene="" /locus_tag="" /product="putative side tail fiber protein" /translation="MAVKISGVLKDGTGKPVENCTIQLKARRTSSTVVVNTVASENPD EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSQPGTLNDFLGAMSEDDVRPEA LRRFELMVEEAARHAEEAKKNAGEAETSARNAGISSSKAEASAANADTSAGDASESAR QAAESAAAAKQSEEASSSSASAAAQKASESSQSAAEAELSRKTAESAAGNAARDATTA TEKARESAESARSAEQSRIAAEEAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGD TGPVGATGERGPAGDAGPAGPQGPKGDMGERGETGLTGNAGPQGPKGDTGAAGPAGPQ GPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSNGWFPGTDGALITGL TFLDPKDATQVQGLFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE" gene complement(12616..13215) /gene="" /locus_tag="" /db_xref="2147172..2147771" CDS complement(12616..13215) /gene="" /locus_tag="" /product="putative outer membrane precursor Lom" /translation="MRKLYAAILSAAICLAVSVAPAWASEQQATLSAGYLHVSTNVPG SDELNGINVKYRYEFTDTLGMVTSFSYAGDRNRQLTRYSDTRWHEDSVRNRWFSVMAG PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF" gene complement(13282..16761) /gene="" /locus_tag="" /db_xref="2147838..2151317" CDS complement(13282..16761) /gene="" /locus_tag="" /product="putative host specificity protein" /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVEGLKS VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR TITSANIDRLRFTFGVQALVETNSKGDRNPSQVRLLVQIQRNGGWVTEKDITIKGKTT SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQGYPNTALV GVKVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTLKPAYSNNPAWCL WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISIGGRVLAVNSQTRTLTLD REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGLKVKVNRVPDGVAEYSVWGLKLPTL RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL TAEVTADSGEYQVLARWDTPKVVKGVSFMLRLTVAADDGSERLVSTARTAETTYRFRQ LALGNYRLTVRAVNARGQQGDPASVSFRIAAPTAPSRIELTPGYFQITATPHLAVYDP TVQFEFWFSEKRITDIRQVETTARYLGTGMYWIAASINIKPGSDYYFYIRSVNTVGKS AFVEAVGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNP PAFSLTPDGKLTAKNADISGSVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVG KAFPRDSRAPERWPSGTITVRIYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLI VRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLV VVMKKATAGISIS" gene complement(16822..17493) /gene="" /locus_tag="" /db_xref="2151378..2152049" CDS complement(16822..17493) /gene="" /locus_tag="" /product="putative tail assembly protein" /translation="MAATHTLPLASPGMARIRLYGDLQRFGRRIDLRVKTGAEAIRAL ATQLPAFRQKLSNGWYQVRIAGRDVSTSGLTAQLHETLPDGAVIHIVPRVAGAKSGGV FQIVLGAAAIAGSFFTAGATLAAWGAAIGAGGMTGILFSLGASMVLGGVAQMLAPKAR TPTAASTDNGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQV VVIGR" gene complement(17391..18134) /gene="" /locus_tag="" /db_xref="2151947..2152690" CDS complement(17391..18134) /gene="" /locus_tag="" /product="putative tail assembly protein" /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE DYFRMAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRNGQNLYLDNMEAT GFYRVALTEAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR THSLWRHRAWRASAFTGIYNDLAAASTFV" ORIGIN 1 tcataacgcg gcgcgtaggg cttcgcgaat taatgtttca ctgctggcgt cagggcgagc 61 gattttgctc accatgcggc ttgcttcttg tggtttatag cccagcgcca ccagcgcggc 121 aaccgcttct tgttcagcat cgtcggtcgc cgggctggca ggagacgtga gcaccagatc 181 ggcggctggc gtaaagagat cgccgtgcaa acctttaaat cggtctttca tttcgacaat 241 taaacgctcg gcggtttttt taccaatgcc cggcagtttc accagtgctc ccacttcttc 301 acgttcaacg gcattaacga actgctgcgc tgacattccg gagaggatcg ccagcgccaa 361 cttcgggccg acgccgttgg ttttgattaa ctctttaaac aacgtgcgct cttgcttatt 421 gttaaagccg tacagcagct gcgcgtcttc acgcaccaca aagtgggtga aaacgatcgc 481 ttcctgaccc gcttcaggga gttcataaaa acaggtcatc ggcatatgca cttcatagcc 541 tacgccgccc acttcaatta acaccagcgg gggttgtttt tcaatgatga tgcctctgag 601 tctgcctatc acatgacgct cctgcgtaat gaatcaaaga taatgctgta tgataaaaaa 661 atgctggata gatatccagc gaaggatgaa gaaaacttgc gaggcgtccc aacgatctga 721 aaaatggcgc agtataattt attctacagg ttatattgga agcaaatatt tgaatattac 781 atattcagtg aagaaatgcg taataaaaat atacattgcg actcctgaaa taataaattt 841 tttatgctat tacgtatatt catatctatt tcaatggaat gacaacgtga atattaatta 901 ccctgctgaa tatgaaattg gagatatcgt ctttacatgt ataggtgctg ccttatttgg 961 tcaaatatca gctgcatcaa attgctggag taatcacgtc gggatcatta tcggtcataa 1021 cggtgaagac ttcctggttg cagaaagccg ggttcccctt tcaaccatca ccacgctatc 1081 tcgttttatt aaacgttcgt ctaatcaacg ctatgctata aagcgattag acgctgggct 1141 gacagaacaa caaaaacaac gaattgttga acaggttccc tcccggctac gcaaacttta 1201 ccacaccggt tttaaatacg aatcttcgcg ccagttctgt tcaaaatttg tttttgatat 1261 ttataaagaa gcgctatgca ttccggtggg tgaaatagaa acgtttggag aactgttaaa 1321 tagcaatccg aatgcaaaac tcactttctg aaaattctgg ttcttaggtt ctattccgtg 1381 ggagcgtaaa accgtcacgc cagccagttt gtggcatcat ccgggtttgg tgttgattca 1441 cgcggaggga gttgaaacgc ctcagcctga actgaccgag gcggtataac ttaacgcagt 1501 cgccctctcg ccaggttcag ccgcgattcg ctcatctgca tcgcattctg actaacgtgg 1561 cagtgggtga tggcaatcgc cagtgcatcg gcggcatccg cttgtggatt agcgggcagt 1621 ttcagcaagg tgcggaccat atgctgcacc tggcttttct cggcgctacc aatgcctacc 1681 accgtttgct ttacctgacg tgccgcgtat tcaaatactg gcaactcctg attcaccgcc 1741 gccacaatcg ccacgccgcg cgcctggccc agtttcaggg ctgagtcagc gttcttcgcc 1801 ataaagactt gttcaatggc gaaataatca ggctggaact gggtgatgat ttccgtcacg 1861 cccgcataga tgagcttcag acgagacggt aaatcatcca ctttggtgcg tatgcatccg 1921 ctacccaggt aggacagttg cctgcctacc tggcgaatta cgccatagcc ggtcacgcgc 1981 gaacccggat caatgccgag aataatagcc atcacgcgtc tccgttttgc tgtttagcag 2041 gcctcatcag agagtcgctg cgacctcatc agagatttca ccgttatggt aaacttcctg 2101 cacgtcgtcg caatcttcca gcatatcgat cagacgcatc agtttcggtg cggtttctgc 2161 atccatatca gctttggtgg acgggatcat ggaaacttcc gcgctgtctg ctttcagacc 2221 tgccgcttcc agagcgtcgc gcactttacc catttcttcc catgcagtgt agacatcaat 2281 cgcgccgtca tcataggtca caacgtcttc agcacctgct tccagagctg cttccatgat 2341 ggtgtcttca tcgcctttct cgaaggagat cacgcctttt ttgctgaaca gataggctac 2401 ggaaccatct gtaccgaggt taccgccaca tttgctgaat gcatgacgca cttcagcaac 2461 ggtacggttg cggttgtcag acagacattc aatcatgatt gccgtgccgc caggaccgta 2521 accttcgtag atgatggttt ccatgtttgc atcatcatca ccgcccacac cacgtgcaat 2581 tgcgcggttc agtgtgtcac gggtcatgtt gttagacagt gctttatcca ccgccgcacg 2641 cagacgcggg ttagcgtccg gatcgccacc gcccagctta gccgcggtta ccagctcacg 2701 aatgatttta gtgaagattt taccgcgctt agcatcctgc gcagctttac gatgtctggt 2761 gttggcccat ttactatgac ctgccataaa aatatctcca gatagccctg cctgttcagg 2821 cagcgttaat tacaaactgt tcaatcgcct gccggttgct ccaggactta gtgagcgccg 2881 ccgcagcagg cgcatcaagc cacttgtaag ccagatgttc agtgaaaacg atctgccgct 2941 cgtgcggaag cgcaagacag aaccatgatt ccgtattacg cgtcacgccc ggcgcatagc 3001 gatgacgtaa atgtgaaaaa atttcaaact ctaccgtgcg ctgacagtca attaaggtca 3061 gttgttcagc gacaacatca atggtgacct cttcctttac ttcgcgcatg gcagcttgcg 3121 gcgcggtttc accctcttcc acgctgccgg ttaccgactg ccagaaatcg ggatcgtcac 3181 gccgctgcaa catcagcacc cgtttcgtat cttgtgcata gatgaccact aagatcgaaa 3241 cgggacgctt atacacttta tcctccacgc tgcctcttcg ttgactgcct tcgctcatcc 3301 cattcacata gttatctatg ctcatgggag ttcactcagt tgccgccttg atgcaacgcg 3361 aatgatttcg tgtatttgag tcatatcagt tattctcagc cttcttcaca acctgaatgc 3421 tcagctcagc cagtgcagtc gggttagcaa agctcggtgc ttcagtcatc agacacgctg 3481 ccgccgtggt tttcgggaag gcgataacgt cacggatatt gtcggtgccg gtcagcagca 3541 tggtcagacg gtcaagaccg aatgccagac ctgcgtgcgg cggagtaccg tatttcagag 3601 cgtcgagcag gaagccgaat ttctcgcgct gttcctcttc gttgataccc agaataccaa 3661 acaccgtctg ctgcatatca ccattatgga tacgtactga accaccgccc acttcgtaac 3721 cattgatgac catatcgtaa gcgttcgcca ccgcattttc cggtgcagct ttcagttctg 3781 cagcagtcat gtctttcggt gaggtgaacg gatggtgcat tgccgtcagg ccgccttcac 3841 cgtcgtcttc aaacatcggg aagtcgataa cccacagcgg tgcccatttg ctttcgtcgg 3901 tcagaccaag gtctttaccc actttcaggc gcagtgcgcc catcgcgtcg gcaacaattt 3961 tcttgttgtc ggcaccgaag aaaatcatat cgccatcttg cgcggcagta cgatccagga 4021 tggcttcgat gatttctgca ttaaggaact tcgctaccgg gctgttgata ccttccagac 4081 ctttcgcgcg ttcgttaact ttgatgtaag ccagaccttt cgcgccgtag attttaacga 4141 agttaccgta ttcgtcgatc tgcttacggg tcagcgatgc gccgcccgga acgcgcagag 4201 cggcaacgcg acctttcgga tcgttcgccg gacctgcaaa tactgcaaac tcaacagatt 4261 tcagcagatc agcaacgtcg gtcagttcca tcgggttacg cagatccggt ttatcagaac 4321 cataacggcg ttctgcttcc gcaaaggtca ttaccgggaa atcgcccaga tccacgccct 4381 tcacttccag ccacagatgg cgcaccagcg cttccatcac ttcacgcact tgcggcgcgg 4441 tcatgaaaga agtttccaca tcgatctgag taaattcagg ctgacgatca gcgcgcaggt 4501 cttcgtcacg gaagcattta acgatctgat agtagcggtc aaagccggac atcatcagca 4561 gctgtttgaa caactgcggg gattgtggca gcgcgtagaa tttacctttg tgcacacgag 4621 aaggcaccag gtagtcacgc gcgccttccg gcgtggcttt ggtcagcatc ggagtttcga 4681 tgtcgaggaa gccgtggtca tccataaaac ggcgcaccag gctggtgatt ttagcgcggg 4741 ttttcaggcg ctgagccatt tccgggcgac gcaggtcgag gtagcggtat ttcagacgcg 4801 cttcttcggt gttgacgtgg ttagagtcaa gcggcagaac atctgcgcgg ttgatgatag 4861 tcagcgagga cgccagcact tcgatttcgc cggtcgccat atcgcggtta atattttttt 4921 cgtcacgcgc acgtacggtg cccgtgacct gaatgcagaa ctcattacgc agttcagagg 4981 ccagctttaa cgcgtccgca cgatccggat cgaaaaatac ctgcacgata ccttcgcggt 5041 cgcgcatatc gatgaagatc aggctaccaa gatcacgacg acggttgacc caaccacaca 5101 gagtcacctg ctgccccacg tgggacaaac ggagctgtcc acaatattct gtacgcatga 5161 gatatccctt aacttagctg ccggcggatg ccccctgctg cgcaggtgac caagtcgcag 5221 cgttagctgt atgtcacaac tgaatgaaaa aaggcggcta ttatactgga aattctgccg 5281 caccgtaaga gcctggcccg cgctggaacg cctcgttacc actttatatc gggcctgaaa 5341 tcagactcta cgccagtttg ctataaaggt gttgcccgaa ctcataaaaa ttaacaaaat 5401 ttgtcgttcc gccatcggct aatcgcatta aggtgtgagg cacgattttg ttttttcagg 5461 agtcattatg cttgaactta atgctaaaac cactgcgctg gtggtgatcg atttacaaga 5521 aggcatctta ccttttgccg gtggtccaca tactgccgat gaggtagtta atcgcgccgg 5581 gaagctggcg gcgaaatttc gcgccagcgg tcagcccgtg tttctggtgc gcgttggctg 5641 gtctgccgat tacgccgaag cattaaaaca gccggttgat gccccctccc ccgctaaagt 5701 gttgcccgaa aactggtggc aacatccagc tgcattaggt gcaactgaca gtgatatcga 5761 aatcatcaaa cgtcagtggg gtgcgtttta cggtacggat ctggagttgc aactgcgccg 5821 ccgaggtatc gatacaatag tgttatgtgg gatctcgacc aatatcggtg ttgaatccac 5881 cgcccgcaat gcctgggaac ttggctttaa tctggtgatt gccgaagacg cctgtagtgc 5941 cgctagcgcc gagcagcaca ataacagcat caaccatatc tacccacgca tcgcccgtgt 6001 gcgtagcgtg gaagagatcc ttcacgcgtt atgatttaca tcggtctacc gcaatggtcg 6061 catcctaaat gggtgcggtt ggggatcacc agccttgaag agtatgcccg ccactttaac 6121 tgcgtgatac gggattttta aaaatcacta aagaacgccc aagagcatgt gttttcttta 6181 gcataatcaa actgttggat tgccatatca tatgaaaatc ggcaaagttc atatgtaaca 6241 aagtgtccca atcatgcccc aaaatgcccc acaacagata tttttgtccc atgcatgccc 6301 caaaaaatca ctttccctcg ccttgacact gtttatccgt acagttaaaa ataatactgt 6361 atacaaacac agtgtagggg gatttttatg cgtattgaaa tctgcatagc caaagaaaaa 6421 atgactaaaa tgccaaccgg tgctgtggat gcgttaaagg atgaattaac cagacgcatc 6481 agtaagcgtt atgacgatgt agaggtgatc ataaaagcaa ccagcaacga tgccctttca 6541 gttacccgca tcaccgataa agattctgca aaaacatttg ttcaggagac tctgaaagat 6601 acctgggagt ctgctgacga gtggtttgtt cactaataaa cacgtaaaat cggtaacggc 6661 tggaaatcat tcaatcctcg cactatcgaa aagctcacca gtcaacagcg gtaagttctt 6721 tcatacgacg taccgctgtt ttctttatga ttgatagctg tactggtaaa ttatgagcaa 6781 tctgaatcca tgcatgacgt atggcgcctg ttgtgcattt ttccgcgtct ctttttacca 6841 gagcaaaacc aatgatactg acgtagttgt ctcccagaga cttatgcctg tatagcaaac 6901 ctcaaataat ctgggatctc atttcgtagt ttcacaatat caatatccga atcgatatgt 6961 ttctggtaaa acttgtccgc aagcaagttt gctatgctat ctgatgtacg attttttaca 7021 tcccggctca taccatcaca aagagcatct attttcttgc caaaagaagc attccccatt 7081 attacatgat taatagaact ttgtgctgcc ttaatatcaa gacttagttg atatttttga 7141 ctcacaagag aaaagactct ttgcttcact tcagtagtaa ttttttcatt tctttgaaga 7201 cagtaattat caatctcctg attgatcacc cttgatggat ataccatctg ttcatctttc 7261 acccacccat caatattttt agcactctgc ctgcgcactg tatccagtat attgccgcta 7321 aatttgtcaa cagaaaagcg aatagtccgc tctccaattg aacattttat gacctcatca 7381 ttcttccctc ggaaagggtt ccgaaaggaa ttttctctat gacaacttac accaaaagag 7441 ctgaaagatg tacctgtagt cttcatcggc atggtaattc ctttttataa aaatatgttt 7501 acaagattgc atacttgtgt ttattgtagc cagaaaaaac acacatgcaa ataacattct 7561 attagaagtt gtaatgtttg agttacatat catgatcggt atgttgactt ttgttaccaa 7621 tatagttcac aaaatgggtt gaaaaggata ataatatgcc tgtcatatta aatttttcta 7681 atggaagtgt attgccggaa aatgagctgg aggctttacg gcatattgca agaagcaatc 7741 agaatgacac tattaccata ggaagccgta atatgaggct tcattatatc cagtttatgg 7801 atggttttag tgtagagcct attcctggtg gacttaggga ccgtcttggg gcaagagaga 7861 ctcatcatct cgcagacagc ctgacaagac agcttaacgg aggtaacact tttctgcagg 7921 catacagctt atatctggag cagaggcacg ctgccccgct tgtgcaggaa agcgtcataa 7981 aaacactact ggatcgaata aatttgaatg catttcccgt tagtttacaa gacttttcct 8041 gtactgagga gtatcttaat tgtccgataa cgctacatat tcctgaaacc ggtgtttttg 8101 tcagaaatgc tctaagttca gaaatatgtg cattatatga tcagaaagca ttgactgaac 8161 ttattcggcg caacgcccta catccattca gccgtgaacc cttttctcca gaaatgatta 8221 taagaaaaga gacatgtcat tttaatatag caaaacaatg tttttgcgca ttccccatat 8281 acccccttca acaaaatagt atttaaaaat aaaaatacaa tataagaagc atattttcaa 8341 taatttaatc accatataac aaacatatag agaggagact gtttatgccc aaaatatcat 8401 cagttgtatc atcatgttac tatttgttca gagaacatca acaactttca aatgaaacaa 8461 caatgacgaa ctccgcctcc agaagaattg ttcataaaga acatggtata tctttaaaat 8521 ccgttcccgt atggttggct acagctaaaa ctccccttgc tctactcaat ggcaaacata 8581 caagaagtca ctcatttatt attgcaggga ccccaggaat gggaggcagg agcggagccc 8641 aatactatgc cataaacagt gatgataaac gctcccgcat agacattgac tctttatttt 8701 taaaaaagtt aaataatgcg cgaaatcaaa ataaattttc aatcgatgta aaagaaacgg 8761 ttataaaact acaaggacaa aaatttacat gcattgaaga ttttcataaa aagtatagtg 8821 aaatcaggct aaagaccaat agcaatattc aacaaaaaca aattacagat gaagtaaaat 8881 cacttacata tttgattcct tcagaaaaaa aagagatgtg gatatataaa aacaatggaa 8941 aagataatgc aaaaccaaac ttaggagagc gagacgtaag aatgttcgaa aatattagtc 9001 ctgatgatac agataagata acaggaagga aattttcaga gttaggtgag tatctttatt 9061 caggaaatgt cataaaactc agtcagttat caattcgtta cctacccaat atcaactcaa 9121 tctcattaat agagacaaaa cagagtttgt tgctacatcg attatattca gatgaagtac 9181 ttcagagaaa tggaacactt atcccgacac cactacatga agaaaaatca attcccgctg 9241 ccaatataaa aacaatgctc aacaacatac caacttacaa aatgttaccg ccattcacag 9301 aaacacaagg taattgttct tctggcgcag ccacgttttt acgcaaatca ggcgccgaag 9361 aaaaagatat tcttgcatgt agcccccgaa attatgggct gcatcataac ataaaaacat 9421 gggacccctt ggttagaaat taaggatcca aatattatat atttcatata aagcaaggaa 9481 aatattgcct gaataattgt tcaggcaata tatccttaca tggcactatt ataataaact 9541 attaatataa aaacacacca acagaaaaaa ttaagcatca cttgcaacaa aggcttcttt 9601 ttttgaatca aagtgacatt cgtcttttct catgatcatt gattctgtta taggttctcg 9661 actcagagga tgagctccac cagtttcaac aagttgcact aacgcgtcct tatcatatag 9721 agagcatatc tcagcacctc gtgagtttct catgaacact ccattctcag gtgtgtccag 9781 cgttatcggg catgtcaaaa atgactccgg gcaagaaaag tgattagaat ccggtctaaa 9841 tacacaagaa tttatttttt ccattaatat tttattactt gttttatttt ctctgtgttc 9901 tgccatgaca ctctgaaaat agttattaac actacttaaa aaatcgacac ctccatttaa 9961 ttgcctttcc agagccacag cccttctctc cattcgatgc tcacgcccca atagcctatc 10021 cagtaagcct cctctcaccg gttcaactga aaatccatcc agtagttgga catagtgaac 10081 agaatattgg ccactaccaa tggatattct tattccactt tcaagtctgg ctgcatcctg 10141 caaagactgc actcctgcag gagataattg agatatactt gggatactta aggtggtaac 10201 aggcataaaa acctcattca gtaattcata tcagtttgca ggatgtttca ttaaataaag 10261 ggtaatgttc atttcaatta ccctttataa cgaagtttcc tctggtatcg tcataaatgc 10321 gcattcttca tgttttacaa ttattgatgc cgttattggt tcccgggtca gtgggtgggg 10381 taagccttca ccagtcaaac gagaaaatgc agcggcatca aataaagtac atacatctga 10441 accatctgaa ttcttcacaa aaataccttt ttcaggctgc tccagtgtaa ttggacattg 10501 aagcacctca ccagtacagt gaagtttttc aatatcaaca gtaaaggtac attccgatat 10561 tttggcctgc agagagttct cttgtcgttg cgccgccatt ccaggaagca cgcttaacat 10621 cctgtttctg agcgcatcaa ctccatcatt aaaaacaata ttcaataatt ctgcataaac 10681 cactcccagc ccttcacttt ctgctaaaaa acggcctgta tctagtatat aagaaactct 10741 aactctctcc ccacccagga gaaatccacc aatctgccct tccattacct gctgacgcat 10801 ctccgccatc tcattcgcga atgaggtcga tgatatatat gatactaatc caggcattac 10861 catattcctt catacagata aatatttcct ctgggcttca taacaaacat tccccataca 10921 tgacaacaaa aaccggagcc ggactccggt ttttgtgaaa ctgtcggcta tttcatcccg 10981 ccaatatttt cccacgtccc gtcagcacgc aggatttgca gcggtcttac cacgcactgt 11041 atctgctttt tatccgcatc cagtatcacc acctgcgtga ttaccctgtc ctgctccggg 11101 ataatgccat tctcatctga ctccaggatg tctgccggcc ccagtcgcag ctgtgctgta 11161 agtaactccc cgtgttcacg gtcatcatgc tttccgcaac cgcacagacg ctgcataagt 11221 ttttttagta cgttcatgtc attctcctgt tctgcctgta tcactgccca cttcatccag 11281 ccccttgaca tcctgccacg gcccgtcacc aaacctgacc tgcaaatgct gaaacagccc 11341 ctgaacctgt gtggcatctt tggggtcaag aaaggtcagt ccggtgatga gcgcaccatc 11401 tgtacccggg aaccagccat tgctgtttgt ctcaataatg ctcgccggcc ccagacgaaa 11461 acggatttgt gtctcccccg ggtcgccctt cggtccctga ggtccggttg cccccaccgg 11521 gccagccgca cctgtttctc ctttcggtcc ctgtgggcct gccgggcctg ccgcaccggt 11581 atctcccttt ggaccctgtg gacctgcatt tcccgtcaga ccggtctctc cccgctctcc 11641 catgtcacct ttcggcccct gcgggcctgc cggaccagca tcacctgccg gtccccgttc 11701 gccggttgcc ccgacagggc cggtgtcacc gcgctctccc ttatcaccct tcggcccctg 11761 aggacccgcg ggacccggtt ccccctttgg cccgggaggc cccaccacgg tcgggattcg 11821 gtttacggct tcttccgccg ctatcctgct ttgttccgct gaccgtgcgc tttctgctga 11881 ctcccgggct ttttctgttg cggtcgttgc atccctggct gcattaccgg ctgcactttc 11941 tgccgtcttt cttgacaatt cagcttctgc tgcactttgt gatgactcac tggctttttg 12001 agcggccgca gaggccgagg acgaggacgc ctcctctgac tgctttgcag cggctgcact 12061 ttctgccgcc tgccgggctg actccgatgc atcccctgct gaagtgtcag catttgccgc 12121 gctcgcttcc gccttactgg atgatatgcc ggcattcctc gcggacgtct ccgcctctcc 12181 ggcattcttc ttcgcctcct cagcgtgacg cgccgcttct tccaccatca gttcaaaacg 12241 acgcagtgcc tccggccgga cgtcatcctc cgacatggca ccaagaaaat cattcagcgt 12301 ccccggttga gaatcttcat acacggtgat ggtcccggca tgtgacggcg ggaatccttc 12361 caccaacaga atgacgctgt actgaccgta ctcaacgtcc atgctgtaac gaccggcttc 12421 atccggattt tcagaggcca ccgtgttcac caccaccgtg ctgctggtcc gtctggcttt 12481 cagttgaatg gtgcagttct ctaccggttt tcctgtgccg tctttcagta cacctgaaat 12541 ctttactgcc atattcaccc cacaaaaaag cccgcctgaa ccggcgggct gtcataacac 12601 tgtgttacct ggctaatcag aatttatagc cgacacccac gatgaagccg tcagtgcgcc 12661 agtcgccact gccggagcct tcataagcaa tatcaatggc cacggattcg gtcgggttaa 12721 actgcacgcc agccccccac gccagagacg tgttgctgtg gcgaccgtca tcacttccgg 12781 tcagcacgtc gtgcgttttc cccttgttgt cagttacgcg gagataatcc ccggagaaag 12841 tcgacacacg gctgtaagcc acacccgcca tcgcatacgc gctgaaccat tcattcacgc 12901 gcacagacgg ccccgccatt acgctgaacc agcggttacg aacggaatct tcatgccagc 12961 gggtatcgct gtaacgggta agctggcgat tcctgtctcc tgcatagctg aatgacgtca 13021 ccatccccag cgtatccgta aactcataac ggtatttcac gttaatcccg ttcagttcat 13081 cgctgccagg aacgttcgtc gagacatgaa gataccccgc gctcagcgtg gcctgctgct 13141 cagacgccca tgcaggcgcg acggatacgg ccagacagat ggctgcggac aaaatggcgg 13201 cataaagttt acgcataatt acctctcgct tttctgcaat aaaaaaggcg tcatttctga 13261 cgcccgttct gggttataaa attcagctga tactgatacc tgctgtggct ttcttcatca 13321 ccacaaccag caaatcgctg atacttgctg tgggatacca gttattcacc agccatgctg 13381 ataccgaaaa ctccagcgtc atgtgaccgt gaccggcagg catatcaata acgccactgt 13441 aaatcagcgt attatccagc gcggtacggt tataaatttc agcaccgttt ttccgcacta 13501 tcagacggca tgaggagtaa atatcagtat gctctctctc atgtttagcg ccgctgaatg 13561 ccaccgccgg aataacaatc tgccggtcaa acggctgatc gtcataaatc ctgacggtaa 13621 tggtccctga tggccaccgt tccggtgcac gggagtcccg ggggaaagct ttgcccactg 13681 ttttaacgag atcgccttca atctggttcg cggacagttt tcccagaacc cggcagttct 13741 cgttaatcgt gacgttgttg agcgtcccgg agttcgcatt cacactgcca ctgatatccg 13801 catttttagc ggtcagcttt ccgtccggtg tcagggaaaa tgccggagga ttgccgccac 13861 tggtaatggt gggagccgtc agatatttca ggaacacttc attcatgaat atctgatcac 13921 cctgaccaac aaacatcggc tttgtgttgc catttgcagg attaatcatc gcaatcctgt 13981 ctgccgccag cagcacctga ctctgcatgc cgtcgggggt gttctcaata ccggccccga 14041 tacccgcaat ataaaggcgt ccgtcctgca tctgttgcag cttcactgcc cacatgctgt 14101 tcaggttatt atttgtatca acctgaacct tctgtatctg ctgaattgcc gcactctggt 14161 cttccagttt cttattgacg gtctgtgtga tttcattgct gacatccgta atggacgtcc 14221 tgatttcagc caggtcaggc gcaagctgac cgttatcaat ctgcgtccac aactcctgag 14281 ccagatgggt tttccctatc tcgcctttga aaaaatccag gtaaccttcc gcatcatcgc 14341 tcgcccgacc gacggcctcc acgaatgccg atttgccaac ggtgttcaca ctgcggatat 14401 aaaagtagta atcagaaccc ggcttaatat tgatactggc ggctatccag tacatccccg 14461 tgccaaggta gcgggctgtg gtttcaacct gcctgatatc ggtaatccgc ttttccgaga 14521 accagaactc aaactgtacc gtcgggtcat aaaccgcaag atgcggcgtg gcggtgatct 14581 gaaaatagcc cggcgtcagc tcaatccgcg acggcgctgt cggtgcggca atccggaacg 14641 ataccgacgc agggtctccc tgctgccccc gggcatttac cgcccggact gtcagcctgt 14701 agttccccag cgccagttgc ctgaagcggt atgtggtttc cgccgtccgg gccgtgctga 14761 ccagccgctc actgccgtca tccgcggcca cggtcaggcg aagcatgaaa ctcacgccct 14821 tcaccacctt cggcgtgtcc cagcgggcca gtacctgata ctccccgctg tctgcggtga 14881 cttcggcagt caggtgctgc accgctggcg gcgtgacacc attcaccgtg ccgctctggt 14941 cgccgtcaaa gtgcgccccg ttatccacga tggcttcttt ttccggtaca tgctgcacgg 15001 cagtgatggc atacgtgccg tcatcgttct cacggatact cacgcagcgg aacaggcgct 15061 gacgcaacgt cggcaacttc agcccccaca cactgtattc tgcaacgccg tcaggaaccc 15121 ggttcacttt caccttaagt ccgtcggtga cggactgaac ttccacgctg accggattac 15181 cacttccgtc aaccaggctt atcagcgtgg taccggagga tggcagcgtg atttcacggt 15241 cgagcgtcag cgtccgggtc tggctgttca ccgccagcac gcgaccaccg atgctgatac 15301 cggcatagtc atcatcgcag atttcaataa catcgcccgg cacatggcga agcccttctg 15361 cgcccacgct gaaatccacg gtctgcgttt ccagcagttc cgttttaatc agccacagcc 15421 cggctcggtg tgcctgcccc cgactggtac aaccaaaggc atccatcttc gtgacattac 15481 gaccgtaacg ggcaatggcc tgcgtatctt caacaagctc tgtcgccgtc tcccagccgt 15541 tattcgggtc aatccagttc acctcaacgg cattatggcg gtccttcagg gcgctgaagc 15601 tgtagcggaa cggcgcacca tcatccggca tcaccacatt actgcggtta taggtccaca 15661 ccttatctga tggtcggtcc tgcacgaacg tcagcgtctg cccgttccat accggcatac 15721 agcgcatcgc cgagcagaaa tcactgagca catcccacgc cttacgctgt gtggtcaggt 15781 acgcattaca ggtaatgcgc ggctccgtgc cgccaaagcc gtccggcacc gactggtcgc 15841 agtactggcc gatgacatac agcgcccatt tatccacatc cgccgcacca agacgtttcc 15901 ccatgccgta gcgcgggtgg gtcagcatat cccacagaca ccaggccggg ttgttgctgt 15961 atgccggttt taacgttccg tcccagatac cgctgtattg ccgcgtctgc gggttatagt 16021 tcgacggcac ctgcagaata cgcccgcgaa gatgataatt acggctcacc tgctggctgc 16081 cgaactgctc cgaatccacc tttacgccga ccagtgccgt gttcgggtag ccctgtttca 16141 catcgatgat ttcggtgtat gacgaccaga gcgttttgtt ctgcagctgg tctgtggtgc 16201 tgtccggcgt cattctgcgc atccggatat taaacgggcg cggcggcagg ttatccacca 16261 ccaccgaggc cagatactgt gaggtggttt tgcccttaat ggtgatgtct ttttccgtca 16321 cccagccacc gttacgctgt atctgaacca gcaggcgaac ctgcgatgga ttcctgtccc 16381 cctttgagtt ggtttccacc agtgcctgca caccgaaggt aaagcgcaga cggtcgatgt 16441 ttgccgacgt gatggtccgg gttatcggcg tgtcatattt cacttccgta cccagcaccg 16501 tctcggagcc ggaggattca aacccttcag gcggtgtctg ctcctgctca ccggcccgga 16561 acaccaccgt gacgccggag atattggtat tcccctcact gtccagcacc ggcgtactgt 16621 tcagcagcac gctttttaat ccctccaccg gaccttcaat cggtccttca ctgatggcat 16681 caatcacact cagtaactgc gtggatttca ggttgtcctt cgcttcgcgc ggggtatgcc 16741 ccttactgct gcctttaccc attcctcact ctccagaaac gataaaaccg cccgcaggcg 16801 gtttcacata aaatgttttg catcagcgac caatcaccac aacctgacca ccgtcccctt 16861 cgtctgccgt gcttatctcc tgagaaacca cacgtgaccc cacgcgcatt tcaccgtaca 16921 gaacaggcag aacattgccc tgggcaacca tgttatccag tgaggagaaa taggtgttct 16981 gtttgccgtt atctgtactt gctgccgtgg gcgtcctggc tttcggtgcc agcatctgcg 17041 ccacaccacc gagcaccata ctggcaccga gagaaaacag gataccggtc ataccaccgg 17101 ccccaatggc tgccccccat gctgcaaggg tggctccggc agtaaagaat gatccggcaa 17161 tggcggcagc ccccagaaca atctggaata cgccacctga cttggccccg gcgactctgg 17221 gaacaatatg aatcacagcg ccgtcaggca gagtctcatg taactgcgcc gttaacccgg 17281 acgtgctgac gtcccgcccg gcaatccgta cctgatacca gccgttgctc agtttctgac 17341 gaaacgccgg gagctgtgtg gccagtgcgc ggatagcttc agcccccgtt ttcacacgaa 17401 ggtcgatgcg gcggccaaat cgttgtaaat ccccgtaaag gcggatgcgc gccatgcccg 17461 gtgacgccag agggagtgtg tgcgtcgctg ccatttgtcg gtatacctct ctcgtttgct 17521 cagttgttca ggaatatggt gcagcagctc gccgtcacca cagtaaatgg cggcatgatt 17581 cggcaccgat gaaccaaaac agcacagcag cacgtcgcca ggctgcgcct ctgtcagtgc 17641 gacacggtaa aaaccagtcg cctccatatt gtcaagatag agattctgac cgttacgcca 17701 ccagtcatcc ccgcgatgaa aatccggcat ctcaatcccc gccagatgat aagcatcccg 17761 gaacagcgtg taacagtccg tcaccccgtg ctcaaagcga cgcccggtga gatgcggcac 17821 acagcggaac ttgtgaatcg ccccccggca gaccagccac cacggcaaat cactctgcac 17881 ctgcagccgc cggtcagcct cactcagcca gggcagacca ccgggatgac tgtggaccag 17941 tgccacaatc tcaccctgca tctctgcctg cagccagtcc tccggagcca tccggaaata 18001 atcctccggc tcaccggaaa tattcacgca gggaaaatat ctttccccct ccggcgttct 18061 taccacgaag ccgcacgact ccgctggcgc acatcgccgg gcgtgcgcca gaatggctga 18121 ttctgtctct gtcat //