Pre_GI: BLASTP Hits

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Query: NC_018939:547793:560014 Helicobacter pylori 26695 chromosome, complete genome

Start: 560014, End: 561582, Length: 1569

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_000915:547783:5600045600045615721569Helicobacter pylori 26695, complete genomecag pathogenicity island protein (cag8)0910
NC_008086:513407:5261765261765277471572Helicobacter pylori HPAG1, complete genomecag pathogenicity island protein X0904
NC_017362:506950:5190465190465206141569Helicobacter pylori Lithuania75 chromosome, complete genomecag pathogenicity island protein X VirB9-like protein0902
NC_017359:813500:8186818186818202491569Helicobacter pylori Sat464 chromosome, complete genomecag pathogenicity island protein (cagX, cag8)0902
NC_014256:683384:6884866884866900541569Helicobacter pylori B8 chromosome, complete genomecag pathogenicity island protein X0901
NC_017367:562918:5745865745865761541569Helicobacter pylori F57, complete genomecag pathogenicity island protein0900
NC_017355:493237:5052035052035067711569Helicobacter pylori v225d chromosome, complete genomeCag80899
NC_000921:511642:5235485235485251161569Helicobacter pylori J99, complete genomecag island protein0899
NC_010698:819912:8310828310828326501569Helicobacter pylori Shi470, complete genomecag pathogenicity island protein (cag8)0899
NC_017358:563336:5745045745045760721569Helicobacter pylori Cuz20 chromosome, complete genomecag pathogenicity island protein (cagX, cag8)0897
NC_017378:502806:5145665145665161341569Helicobacter pylori Puno120 chromosome, complete genomecag pathogenicity island protein (cagX, cag8)0897
NC_017354:848500:8536958536958552631569Helicobacter pylori 52 chromosome, complete genomepenicillin-binding protein0897
NC_011498:553525:5656845656845672521569Helicobacter pylori P12, complete genomecag pathogenicity island protein X VirB9-like protein0896
NC_017360:1052473:1057779105777910593471569Helicobacter pylori 35A chromosome, complete genomecag pathogenicity island protein0895
NC_017376:538000:5512215512215527861566Helicobacter pylori SNT49 chromosome, complete genomecag pathogenicity island protein X0892
NC_017063:800156:8126018126018141661566Helicobacter pylori ELS37 chromosome, complete genomecag pathogenicity island protein X0890
NC_017366:535188:5474685474685490331566Helicobacter pylori F32, complete genomecag pathogenicity island protein0890
NC_017379:505350:5173845173845189491566Helicobacter pylori Puno135 chromosome, complete genomecag pathogenicity island protein0889
NC_017365:848500:8536808536808552451566Helicobacter pylori F30, complete genomecag pathogenicity island protein0889
NC_014560:518582:5237215237215252861566Helicobacter pylori SJM180 chromosome, complete genomecag pathogenicity island protein X0888
NC_017375:872478:8774818774818790461566Helicobacter pylori 83 chromosome, complete genomecag pathogenicity island protein0887
NC_011333:514464:5265065265065280711566Helicobacter pylori G27 chromosome, complete genomecag pathogenicity island protein X0886
NC_017368:852490:8574888574888590531566Helicobacter pylori F16, complete genomecag pathogenicity island protein0886
NC_014555:502151:5137925137925153571566Helicobacter pylori PeCan4 chromosome, complete genomecag pathogenicity island protein X0885
NC_017371:530673:5429335429335444981566Helicobacter pylori Gambia94/24 chromosome, complete genomecag pathogenicity island protein X0885
NC_017357:495213:5089165089165103641449Helicobacter pylori 908 chromosome, complete genomecag island protein0814
NC_017381:500699:5101915101915116391449Helicobacter pylori 2018 chromosome, complete genomecag island protein0812
NC_017374:498588:5080915080915095391449Helicobacter pylori 2017 chromosome, complete genomecag island protein0812
NC_016513:54802:607116071161601891Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeCmgb94e-0963.2
NC_011092:76993:955129551296405894Salmonella enterica subsp. enterica serovar Schwarzengrund strP-type conjugative transfer protein VirB96e-0756.2
NC_019973:5694620:570459157045915705472882Mesorhizobium australicum WSM2073, complete genometype IV secretory pathway, VirB9 component5e-0653.1
NC_015675:6276357:633030263303026331183882Mesorhizobium opportunistum WSM2075 chromosome, complete genomeP-type conjugative transfer protein VirB95e-0653.1
NC_014923:5765660:577563157756315776512882Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completeP-type conjugative transfer protein VirB95e-0653.1