Pre_GI: BLASTP Hits

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Query: NC_018939:547793:554216 Helicobacter pylori 26695 chromosome, complete genome

Start: 554216, End: 559999, Length: 5784

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_000915:547783:5542065542065599895784Helicobacter pylori 26695, complete genomecag pathogenicity island protein (cag7)02881
NC_017362:506950:5132665132665190315766Helicobacter pylori Lithuania75 chromosome, complete genomecag pathogenicity island protein (cag7, cagY)02720
NC_017365:848500:8552608552608610405781Helicobacter pylori F30, complete genomecag pathogenicity island protein02695
NC_017354:848500:8552788552788609745697Helicobacter pylori 52 chromosome, complete genomeconjugation TrbI family protein02629
NC_010698:819912:8326658326658382295565Helicobacter pylori Shi470, complete genomecag pathogenicity island protein (cag7)02575
NC_017376:538000:5458135458135512065394Helicobacter pylori SNT49 chromosome, complete genomecag pathogenicity island protein (cag7)02556
NC_017366:535188:5414455414455474536009Helicobacter pylori F32, complete genomecag pathogenicity island protein Y VirB10-like protein02551
NC_017378:502806:5088765088765145515676Helicobacter pylori Puno120 chromosome, complete genomecag pathogenicity island protein (cag7)02536
NC_017360:1052473:1059362105936210647555394Helicobacter pylori 35A chromosome, complete genomecag pathogenicity island protein02531
NC_017372:855384:8620738620738673525280Helicobacter pylori India7 chromosome, complete genomecag pathogenicity island protein (cag7)02512
NC_017367:562918:5691785691785745715394Helicobacter pylori F57, complete genomecag pathogenicity island protein Y VirB10-like protein02508
NC_017379:505350:5117665117665173695604Helicobacter pylori Puno135 chromosome, complete genomecag pathogenicity island protein02501
NC_017355:493237:4998824998825051885307Helicobacter pylori v225d chromosome, complete genomecag pathogenicity island protein02427
NC_000921:511642:5180745180745235335460Helicobacter pylori J99, complete genomecag island protein02251
NC_014560:518582:5253015253015307815481Helicobacter pylori SJM180 chromosome, complete genomecag island protein02239
NC_017371:530673:5371025371025429185817Helicobacter pylori Gambia94/24 chromosome, complete genomecag pathogenicity island protein Y VirB10-like protein02186
NC_017368:852490:8590688590688644585391Helicobacter pylori F16, complete genomecag island protein01816
NC_011498:553525:5599645599645656695706Helicobacter pylori P12, complete genomecag pathogenicity island protein Y VirB10-like protein01771
NC_017375:872478:8809778809778844533477Helicobacter pylori 83 chromosome, complete genomeDC-EC Repeat superfamily protein01710
NC_014256:683384:6900696900696955345466Helicobacter pylori B8 chromosome, complete genomecag pathogenicity island protein Y01699
NC_008086:513407:5202275202275241143888Helicobacter pylori HPAG1, complete genomecag pathogenicity island protein Y01692
NC_017359:813500:8202648202648254235160Helicobacter pylori Sat464 chromosome, complete genomecag pathogenicity island protein (cagY, cag7)01654
NC_017063:800156:8070168070168125865571Helicobacter pylori ELS37 chromosome, complete genomecag pathogenicity island protein (cag7)01501
NC_017358:563336:5694205694205718042385Helicobacter pylori Cuz20 chromosome, complete genomecag pathogenicity island protein (cagY, cag7)01388
NC_017357:495213:5058855058855075881704Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein01031
NC_017381:500699:5071275071275087281602Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein0992
NC_017374:498588:5050165050165066171602Helicobacter pylori 2017 chromosome, complete genomecag pathogenicity island protein0992
NC_008086:513407:5241735241735261611989Helicobacter pylori HPAG1, complete genomecag pathogenicity island protein Y0874
NC_017375:872478:8790618790618809471887Helicobacter pylori 83 chromosome, complete genomehypothetical protein0799
NC_017374:498588:5066765066765080761401Helicobacter pylori 2017 chromosome, complete genomecag pathogenicity island protein3e-173610
NC_017381:500699:508787508787509452666Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein3e-96355
NC_017357:495213:507751507751508416666Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein4e-95351
NC_017381:500699:509590509590509976387Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein7e-26120
NC_020301:1449616:1448453144845314496191167Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genometype IV secretion system protein VirB102e-22109
NC_016513:54802:6161261612628831272Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeconjugal transfer protein TrbI/VirB105e-22108
NC_010170:3908500:3923502392350239246351134Bordetella petrii, complete genometype IV secretion system protein VirB104e-22108
NC_016845:3448881:3476000347600034772501251Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,type IV secretory pathway VirB10 component4e-21105
NC_020300:1344453:1344453134445313456161164Bartonella australis Aust/NH1, complete genometype IV secretion protein VblB105e-21105
NC_019973:5694620:5703452570345257045941143Mesorhizobium australicum WSM2073, complete genometype IV secretory pathway, VirB10 component7e-21104
NC_015675:6276357:6329163632916363303051143Mesorhizobium opportunistum WSM2075 chromosome, complete genomeconjugation TrbI family protein7e-21104
NC_014923:5765660:5774492577449257756341143Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completeconjugation TrbI family protein7e-21104
NC_009792:859228:8758598758598771031245Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein6e-21104
NC_020181:473170:4898024898024910461245Enterobacter aerogenes EA1509E, complete genomeInner membrane protein of type IV secretion of T-DNA complex, TonB-like, VirB106e-21104
NC_012731:3411161:3456877345687734581271251Klebsiella pneumoniae NTUH-K2044 chromosome, complete genometype IV secretory pathway VirB10 component2e-20103
NC_013592:2968500:3005132300513230063731242Dickeya dadantii Ech586, complete genomeconjugation TrbI family protein5e-20101
NC_017381:500699:509994509994510176183Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein3e-1999
NC_016612:5296076:5294782529478252960861305Klebsiella oxytoca KCTC 1686 chromosome, complete genomeconjugation TrbI-like protein5e-1998.6
NC_011092:76993:9640296402975981197Salmonella enterica subsp. enterica serovar Schwarzengrund strTriI protein7e-1894.7
NC_012912:1701231:1700032170003217012341203Dickeya zeae Ech1591, complete genomeconjugation TrbI family protein1e-1794
NC_009254:365812:3718713718713730971227Burkholderia vietnamiensis G4 chromosome 3, complete sequenceconjugation TrbI family protein1e-1793.6
NC_016818:1795576:1824749182474918260441296Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completetype IV secretory pathway, VirB10 component2e-1793.2
NC_014500:3097362:3154529315452931557371209Dickeya dadantii 3937 chromosome, complete genomeInner membrane protein forms channel for type IV secretion of T-DNA complex (VirB10)2e-1792.8
NC_011283:1811000:1842712184271218440191308Klebsiella pneumoniae 342 chromosome, complete genomeconjugation TrbI-like protein4e-1792
NC_011001:372185:3870723870723882951224Burkholderia cenocepacia J2315 chromosome 2, complete sequenceputative type IV secretion system protein VirB106e-1585.1
NC_016814:18000:3574535745369561212Sinorhizobium fredii HH103 plasmid pSfHH103c complete sequenceType IV secretion system protein virB106e-1584.7
NC_008061:2106848:2113004211300421142271224Burkholderia cenocepacia AU 1054 chromosome 2, complete sequenceconjugation TrbI-like protein9e-1584.3
NC_010515:1124298:1130454113045411316771224Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceconjugation TrbI family protein2e-1483.2
NC_015593:1587684:1598790159879015998811092Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeconjugation TrbI family protein8e-1480.9
NC_017357:495213:508565508565508897333Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein3e-1379
NC_017271:2935643:2969405296940529706671263Xanthomonas campestris pv. raphani 756C chromosome, completeVirB10 protein2e-1276.3
NC_012751:409333:418766418766419431666Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeVirB10 conjugal transfer protein5e-1275.1
NC_003902:2933121:2948624294862429498051182Xanthomonas campestris pv. campestris str. ATCC 33913, completeVirB10 protein5e-1171.6
NC_007086:1936505:1960414196041419615951182Xanthomonas campestris pv. campestris str. 8004, complete genomeVirB10 protein5e-1171.6
NC_003919:3060484:3084400308440030855691170Xanthomonas axonopodis pv. citri str. 306, complete genomeVirB10 protein6e-1171.6
NC_010688:1908012:1933152193315219343211170Xanthomonas campestris pv. campestris, complete genometype IV secretion system putative channel component VirB48e-1171.2
NC_011071:2733438:2750462275046227517151254Stenotrophomonas maltophilia R551-3, complete genomeconjugation TrbI family protein9e-1170.9
NC_010943:3034366:3048752304875230500051254Stenotrophomonas maltophilia K279a, complete genomeputative putative bacterial secretion system protein1e-1070.5
NC_015947:2752450:2768815276881527700861272Burkholderia sp. JV3 chromosome, complete genomeconjugation TrbI family protein2e-1069.7
NC_013722:2150882:2162487216248721636621176Xanthomonas albilineans, complete genomeputative virb10 protein4e-1068.9
NC_007798:652317:6615286615286629011374Neorickettsia sennetsu str. Miyayama, complete genometype IV secretion system protein VirB102e-0967
NC_013422:1755875:1793675179367517949941320Halothiobacillus neapolitanus c2, complete genomeconjugation TrbI family protein6e-0965.1
NC_015186:491930:4949124949124961711260Acidiphilium multivorum AIU301, complete genomeconjugal transfer protein TrbI2e-0863.5
NC_005090:1033746:1050597105059710517001104Wolinella succinogenes DSM 1740, complete genomeCOMB35e-0861.6
NC_015186:2839668:2855282285528228565591278Acidiphilium multivorum AIU301, complete genomeconjugal transfer protein TrbI8e-0861.2
NC_017357:495213:507545507545507706162Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein1e-0760.5
NC_015850:110364:1668211668211681371317Acidithiobacillus caldus SM-1 chromosome, complete genomeconjugation TrbI family protein1e-0760.1
NC_006371:1743982:1756319175631917574551137Photobacterium profundum SS9 chromosome 2, complete sequencehypothetical protein TrbI2e-0759.7
NC_017249:2109843:2116976211697621181871212Bradyrhizobium japonicum USDA 6, complete genomeconjugal transfer protein1e-0657.4
NC_017375:77142:9799997999992011203Helicobacter pylori 83 chromosome, complete genomeconjugal transfer protein TrbI2e-0656.6
NC_017371:1470582:1512192151219215134001209Helicobacter pylori Gambia94/24 chromosome, complete genomeVirB10 type IV secretion protein2e-0656.2
NC_007797:1451804:1463517146351714648211305Anaplasma phagocytophilum HZ, complete genometype IV secretion system protein VirB103e-0656.2
NC_012026:1135041:1162590116259011639271338Anaplasma marginale str. Florida, complete genomeVirB10 protein (virB10)3e-0656.2
NC_004463:1772541:1776632177663217778341203Bradyrhizobium japonicum USDA 110, complete genomeconjugal transfer protein3e-0655.8
NC_014256:485969:5179145179145191221209Helicobacter pylori B8 chromosome, complete genometype IV secretion system protein VirB103e-0655.8
NC_004842:1132441:1158480115848011598171338Anaplasma marginale str. St. Maries, complete genomeVirB10 protein3e-0655.8
NC_017063:834674:8455588455588467661209Helicobacter pylori ELS37 chromosome, complete genomeVirB10 type IV secretion protein4e-0655.5
NC_006831:4500:1563515635169751341Ehrlichia ruminantium str. Gardel, complete genomeVirB10 protein4e-0655.5
NC_005295:21995:3463334633359791347Ehrlichia ruminantium str. Welgevonden, complete genometype IV secretion system protein VirB104e-0655.5
NC_017358:220900:2382162382162394511236Helicobacter pylori Cuz20 chromosome, complete genomecompetence protein5e-0655.5
NC_017372:748097:7891127891127903141203Helicobacter pylori India7 chromosome, complete genometype IV secretion system protein VirB105e-0655.1
NC_009720:3317642:3333207333320733344631257Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein7e-0654.7
NC_010725:3315007:3319252331925233205171266Methylobacterium populi BJ001, complete genomeconjugation TrbI family protein7e-0654.7
NC_011498:1391788:1402591140259114038291239Helicobacter pylori P12, complete genomeVirB10 type IV secretion protein8e-0654.7
NC_015850:2048251:2087030208703020884121383Acidithiobacillus caldus SM-1 chromosome, complete genomehypothetical protein9e-0654.3