Pre_GI: BLASTP Hits

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Query: NC_018939:454000:464987 Helicobacter pylori 26695 chromosome, complete genome

Start: 464987, End: 466132, Length: 1146

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_000915:453958:4650454650454661271083Helicobacter pylori 26695, complete genomehypothetical protein0734
NC_017378:986611:99825099825010014803231Helicobacter pylori Puno120 chromosome, complete genomehypothetical protein0659
NC_017379:996500:1008689100868910113852697Helicobacter pylori Puno135 chromosome, complete genomehypothetical protein2e-103375
NC_017379:996500:100815510081551008685531Helicobacter pylori Puno135 chromosome, complete genomehypothetical protein1e-75283
NC_012973:967380:9771909771909807923603Helicobacter pylori B38 chromosome, complete genomehypothetical protein7e-75281
NC_010002:4572573:4589202458920245925823381Delftia acidovorans SPH-1, complete genomeAAA ATPase1e-53210
NC_010170:4463000:4503816450381645071963381Bordetella petrii, complete genomehypothetical protein1e-53210
NC_017355:997089:100967710096771010057381Helicobacter pylori v225d chromosome, complete genomehypothetical protein4e-52205
NC_017068:1450049:1451482145148214550603579Selenomonas ruminantium subsp. lactilytica TAM6421, completehypothetical protein4e-50199
NC_017355:997089:101036410103641010666303Helicobacter pylori v225d chromosome, complete genomehypothetical protein6e-43175
NC_008757:111292:1320491320491353753327Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, completeSuperfamily I DNA and RNA helicases and helicase subunits-like protein5e-40165
NC_012108:1694817:1696283169628316996063324Desulfobacterium autotrophicum HRM2, complete genomehypothetical protein7e-40164
NC_013410:2691437:2701566270156627047123147Fibrobacter succinogenes subsp. succinogenes S85 chromosome,Superfamily I DNA and RNA helicase and helicase subunits-like protein2e-38159
NC_012654:237175:2407082407082438603153Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequenceprotein kinase domain protein4e-27122
NC_016776:1470596:1472902147290214768103909Bacteroides fragilis 638R, complete genomehypothetical protein2e-26120
NC_007958:2370619:2376912237691223816694758Rhodopseudomonas palustris BisB5, complete genomeATPase2e-24113
NC_011004:2457778:2464559246455924693164758Rhodopseudomonas palustris TIE-1, complete genomeNERD domain protein2e-24113
NC_011000:1397611:1428615142861514334864872Burkholderia cenocepacia J2315 chromosome 1, complete sequencehypothetical protein6e-22105
NC_006370:1810842:1818063181806318230244962Photobacterium profundum SS9 chromosome 1, complete sequencehypothetical protein8e-22104
NC_016831:2667561:2698569269856927007282160Salmonella enterica subsp. enterica serovar Gallinarum/pullorumNERD domain-containing protein7e-21102
NC_014394:707305:7182267182267231904965Gallionella capsiferriformans ES-2 chromosome, complete genomeNERD domain-containing protein9e-21101
NC_012691:2097287:2102959210295921079294971Tolumonas auensis DSM 9187, complete genomeNERD domain protein2e-20100
NC_008312:3923071:3938984393898439439454962Trichodesmium erythraeum IMS101, complete genomeSuperfamily I DNA and RNA helicases and helicase subunits-like6e-2098.6
NC_007645:7136956:7154626715462671595904965Hahella chejuensis KCTC 2396, complete genomeSuperfamily I DNA and RNA helicase and helicase subunit2e-1997.4
NC_009953:3509229:3512609351260935154342826Salinispora arenicola CNS-205 chromosome, complete genomeputative helicase2e-1790.5
NC_006370:1810842:1805869180586918108454977Photobacterium profundum SS9 chromosome 1, complete sequencehypothetical protein5e-1789.4
NC_012779:346998:3701113701113750724962Edwardsiella ictaluri 93-146, complete genomehypothetical protein5e-1789
NC_012731:600518:6093686093686143234956Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomehypothetical protein2e-1687.4
NC_007949:121747:1311081311081359704863Polaromonas sp. JS666 plasmid 1, complete sequenceSuperfamily I DNA and RNA helicases and helicase subunits-like4e-1685.9
NC_017355:997089:101021010102101010371162Helicobacter pylori v225d chromosome, complete genomehypothetical protein6e-1685.5
NC_015167:2498666:2505107250510725084333327Cellulophaga lytica DSM 7489 chromosome, complete genomeserine/threonine protein kinase9e-1684.7
NC_007925:4355413:4357953435795343615253573Rhodopseudomonas palustris BisB18, complete genomeSuperfamily I DNA and RNA helicases and helicase subunits-like1e-1584.3
NC_008758:143907:1804521804521843063855Polaromonas naphthalenivorans CJ2 plasmid pPNAP02, completeSuperfamily I DNA and RNA helicases and helicase subunits-like protein8e-1581.6
NC_000961:801902:8181038181038200731971Pyrococcus horikoshii OT3, complete genomeDNA-binding protein8e-1478.6
NC_008698:903759:9088359088359107241890Thermofilum pendens Hrk 5, complete genomeAAA ATPase2e-1377
NC_013929:7278414:7278414727841472823553942Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein7e-1375.1
NC_009615:1305678:1305678130567813076001923Parabacteroides distasonis ATCC 8503 chromosome, complete genomehelicase1e-1274.3
NC_012560:5276000:5285069528506952887073639Azotobacter vinelandii DJ, complete genomeSuperfamily I DNA and RNA helicases and helicase subunits-related protein1e-1274.3
NC_021150:5234000:5242961524296152465993639Azotobacter vinelandii CA6, complete genomeSuperfamily I DNA and RNA helicases and helicase subunits-related protein1e-1274.3
NC_013720:1605240:1630319163031916322381920Pirellula staleyi DSM 6068, complete genomeAAA ATPase1e-1274.3
NC_014623:2962330:2976897297689729804153519Stigmatella aurantiaca DW4/3-1 chromosome, complete genomeprotein kinase1e-1274.3
NC_015711:8964410:8988065898806589915833519Myxococcus fulvus HW-1 chromosome, complete genomeprotein kinase3e-1273.6
NC_013849:397947:4060154060154078111797Ferroglobus placidus DSM 10642 chromosome, complete genometype III restriction protein res subunit3e-1273.2
NC_009142:2480608:2491194249119424949223729Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein1e-1171.2
NC_014933:3942156:3949999394999939519541956Bacteroides helcogenes P 36-108 chromosome, complete genomehelicase1e-1171.2
NC_007925:4355413:4381145438114543861004956Rhodopseudomonas palustris BisB18, complete genomeSuperfamily I DNA and RNA helicases and helicase subunits-like6e-1168.9
NC_015277:3351504:3356971335697133588631893Sphingobacterium sp. 21 chromosome, complete genomeAAA ATPase7e-1168.6
NC_015385:2135456:2135456213545621384913036Treponema succinifaciens DSM 2489 chromosome, complete genomehypothetical protein6e-1065.5
NC_014256:683384:715093715093715953861Helicobacter pylori B8 chromosome, complete genomeregulator of nonsense transcripts 16e-0962.4
NC_013849:397947:4039154039154057801866Ferroglobus placidus DSM 10642 chromosome, complete genomeAAA ATPase7e-0962
NC_009939:16437:232342323423998765Deinococcus geothermalis DSM 11300 plasmid pDGEO02, completesuperfamily I DNA/RNA helicase-like protein1e-0860.8
NC_017063:775337:7864377864377882481812Helicobacter pylori ELS37 chromosome, complete genomeregulator of nonsense transcripts 11e-0860.8
NC_009792:3225965:3236534323653432400493516Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein2e-0860.5
NC_015761:4355335:4360324436032443638393516Salmonella bongori NCTC 12419, complete genomehypothetical protein2e-0860.5
NC_006396:320853:3224483224483246732226Haloarcula marismortui ATCC 43049 chromosome I, complete sequenceDNA binding protein eukaryotic-like3e-0860.1
NC_014228:3505320:350787435078743508407534Xenorhabdus nematophila ATCC 19061, complete genome2e-0757.4
NC_011750:4775770:4796684479668448002113528Escherichia coli IAI39 chromosome, complete genomeputative superfamily I DNA helicase3e-0756.6
NC_019974:1280500:128386912838691284354486Natronococcus occultus SP4, complete genome4e-0756.2
NC_014393:1022843:1022843102284310257462904Clostridium cellulovorans 743B chromosome, complete genomeputative DNA helicase5e-0755.8
NC_019897:938921:9616169616169645642949Thermobacillus composti KWC4 chromosome, complete genomehypothetical protein2e-0653.9