Pre_GI: BLASTP Hits

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Query: NC_018939:1583653:1587330 Helicobacter pylori 26695 chromosome, complete genome

Start: 1587330, End: 1588490, Length: 1161

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_000915:1583967:1587307158730715884671161Helicobacter pylori 26695, complete genomeselenocysteine synthase0740
NC_017367:1505780:1508599150859915097591161Helicobacter pylori F57, complete genomeselenocysteine synthase0691
NC_017378:1489818:1493117149311714942771161Helicobacter pylori Puno120 chromosome, complete genomeselenocysteine synthase0687
NC_017365:1466500:1466515146651514676751161Helicobacter pylori F30, complete genomeselenocysteine synthase0681
NC_014555:1477934:1477934147793414790941161Helicobacter pylori PeCan4 chromosome, complete genomeselenocysteine synthase0681
NC_017354:1465925:1465925146592514670851161Helicobacter pylori 52 chromosome, complete genomeselenocysteine synthase0677
NC_011498:1571840:1571840157184015730121173Helicobacter pylori P12, complete genomeselenocysteine synthase0676
NC_017371:1601452:1604318160431816054781161Helicobacter pylori Gambia94/24 chromosome, complete genomeselenocysteine synthase0655
NC_000918:707801:7149287149287162861359Aquifex aeolicus VF5, complete genomeselenocysteine synthase4e-38159
NC_015873:790961:8094818094818108781398Megasphaera elsdenii DSM 20460, complete genomeL-seryl-tRNA(Sec) selenium transferase3e-37155
NC_012721:1052883:1053832105383210552951464Burkholderia glumae BGR1 chromosome 2, complete genomeL-seryl-tRNA selenium transferase3e-36152
NC_009053:1785447:1787279178727917886641386Actinobacillus pleuropneumoniae L20, complete genomeL-seryl-tRNA(Sec) selenium transferase3e-36152
NC_010939:1809446:1811278181127818126631386Actinobacillus pleuropneumoniae serovar 7 str. AP76, completeL-seryl-tRNA(Sec) selenium transferase2e-35150
NC_010498:3988351:3991534399153439929251392Escherichia coli SMS-3-5, complete genomeL-seryl-tRNA selenium transferase6e-35148
NC_008751:607209:6109826109826124511470Desulfovibrio vulgaris subsp. vulgaris DP4, complete genomeL-seryl-tRNA(Sec) selenium transferase7e-35148
NC_003869:1812642:1816203181620318176001398Thermoanaerobacter tengcongensis MB4, complete genomeselenocysteine synthase2e-34147
NC_002663:1988000:1992896199289619942781383Pasteurella multocida subsp. multocida str. Pm70, complete genomeselenocysteine synthase3e-34146
NC_012559:731859:7346817346817361141434Laribacter hongkongensis HLHK9, complete genomeSelenocysteine synthase4e-34145
NC_013894:672840:6967136967136980591347Thermocrinis albus DSM 14484 chromosome, complete genomeL-seryl-tRNA selenium transferase6e-34145
NC_016148:1175999:1194571119457111959711401Thermovirga lienii DSM 17291 chromosome, complete genomeL-seryl-tRNA(Sec) selenium transferase6e-34145
NC_004337:3590323:3734155373415537355461392Shigella flexneri 2a str. 301, complete genomeselenocysteine synthase1e-33144
NC_014972:2659388:2669336266933626707811446Desulfobulbus propionicus DSM 2032 chromosome, complete genomeL-seryl-tRNA(Sec) selenium transferase1e-33144
NC_009800:3787320:3789161378916137905521392Escherichia coli HS, complete genomeL-seryl-tRNA selenium transferase9e-34144
NC_010468:111504:1335761335761349671392Escherichia coli ATCC 8739, complete genomeL-seryl-tRNA(Sec) selenium transferase9e-34144
NC_012947:126596:1452341452341466251392Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeselenocysteine synthase9e-34144
NC_014150:582093:5974345974345987891356Brachyspira murdochii DSM 12563 chromosome, complete genomeL-seryl-tRNA selenium transferase2e-33143
NC_010718:1229355:1230422123042212318521431Natranaerobius thermophilus JW/NM-WN-LF, complete genomeL-seryl-tRNA(Sec) selenium transferase3e-33143
CP002516:119935:1423751423751437661392Escherichia coli KO11, complete genomeL-seryl-tRNA selenium transferase3e-33142
NC_014844:1270618:1317169131716913185811413Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeL-seryl-tRNA selenium transferase3e-33142
NC_016902:119935:1423751423751437661392Escherichia coli KO11FL chromosome, complete genomeL-seryl-tRNA selenium transferase3e-33142
NC_014633:713285:7132857132857146731389Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequenceL-seryl-tRNA selenium transferase7e-33141
NC_015856:940625:9617809617809632371458Collimonas fungivorans Ter331 chromosome, complete genomeL-seryl-tRNA(Sec) selenium transferase7e-33141
NC_016584:2244966:2255807225580722571891383Desulfosporosinus orientis DSM 765 chromosome, complete genomeseryl-tRNA(Sec) selenium transferase2e-32140
NC_010322:583842:6130836130836145101428Pseudomonas putida GB-1 chromosome, complete genomeselenocysteine synthase2e-32140
NC_013416:668152:6667616667616681551395Aggregatibacter actinomycetemcomitans D11S-1, complete genomeL-seryl-tRNA selenium transferase4e-32139
NC_016513:974402:9730119730119744051395Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeselenocysteine synthase4e-32139
NC_013282:116649:1362901362901377141425Cronobacter turicensis, complete genomeL-seryl-tRNA(Sec) selenium transferase8e-29128
NC_012225:377441:3969463969463982921347Brachyspira hyodysenteriae WA1, complete genomeselenocysteine synthase1e-28127
NC_004347:103967:1142381142381156591422Shewanella oneidensis MR-1, complete genomeselenocysteine synthase2e-28127
NC_016012:396910:4075114075114088991389Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeL-seryl-tRNA(Sec) selenium transferase8e-28125
NC_007650:832507:8334218334218349081488Burkholderia thailandensis E264 chromosome II, complete sequenceL-seryl-tRNA selenium transferase2e-27123
NC_008570:2768795:2791890279189027933261437Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomeL-seryl-tRNA selenium transferase4e-25115
NC_016024:156000:1731221731221745551434Candidatus Chloracidobacterium thermophilum B chromosome chromosomeseryl-tRNA(sec) selenium transferase2e-24113
NC_015424:2357600:2389841238984123913191479Aeromonas veronii B565 chromosome, complete genomeL-seryl-tRNA selenium transferase5e-24112
NC_014623:4535544:4555837455583745572371401Stigmatella aurantiaca DW4/3-1 chromosome, complete genomel-seryl-tRNA selenium transferase7e-24111
NC_019902:831911:8609598609598624041446Thioalkalivibrio nitratireducens DSM 14787, complete genomeL-seryl-tRNA(Sec) selenium transferase6e-23108
NC_009380:636000:6568396568396581341296Salinispora tropica CNB-440 chromosome, complete genomeselenocysteine synthase8e-21101