Pre_GI: BLASTP Hits

Some Help

Query: NC_018939:1044000:1058391 Helicobacter pylori 26695 chromosome, complete genome

Start: 1058391, End: 1060217, Length: 1827

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017362:1512959:1517467151746715195002034Helicobacter pylori Lithuania75 chromosome, complete genomerelaxase01127
NC_017371:1470582:1474666147466614766962031Helicobacter pylori Gambia94/24 chromosome, complete genomerelaxase01126
NC_000915:1044000:1058373105837310601751803Helicobacter pylori 26695, complete genomehypothetical protein01122
NC_000921:1007519:1045778104577810478112034Helicobacter pylori J99, complete genomehypothetical protein01106
NC_017372:748097:7529897529897550192031Helicobacter pylori India7 chromosome, complete genomehypothetical protein0999
NC_017379:996500:1015676101567610177152040Helicobacter pylori Puno135 chromosome, complete genomehypothetical protein0989
NC_014256:485969:4907314907314921731443Helicobacter pylori B8 chromosome, complete genomehypothetical protein0831
NC_014256:485969:488306488306488938633Helicobacter pylori B8 chromosome, complete genomehypothetical protein3e-72273
NC_015674:1605923:1610985161098516131712187Helicobacter bizzozeronii CIII-1, complete genomehypothetical protein2e-63243
NC_011498:448000:4730424730424749551914Helicobacter pylori P12, complete genomerelaxase3e-22107
NC_017358:220900:2454762454762473831908Helicobacter pylori Cuz20 chromosome, complete genomehypothetical protein9e-22105
NC_017376:57500:8102181021829311911Helicobacter pylori SNT49 chromosome, complete genomerelaxase2e-21104
NC_014256:448710:4670384670384689331896Helicobacter pylori B8 chromosome, complete genomehypothetical protein2e-21104
NC_010698:870312:8942988942988962051908Helicobacter pylori Shi470, complete genomehypothetical protein4e-21103
NC_014555:1526775:1555149155514915570591911Helicobacter pylori PeCan4 chromosome, complete genomehypothetical protein3e-21103
NC_017361:930280:9542129542129561221911Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein3e-21103
NC_011333:1040192:1063336106333610652461911Helicobacter pylori G27 chromosome, complete genomehypothetical protein3e-21103
NC_017367:278916:3019963019963039061911Helicobacter pylori F57, complete genomehypothetical protein2e-20101
NC_000915:1044000:106605310660531066874822Helicobacter pylori 26695, complete genomehypothetical protein3e-20100
NC_009714:113975:1282331282331298551623Campylobacter hominis ATCC BAA-381, complete genomerelaxase/mobilization nuclease domain-containing protein6e-1892.8
NC_017361:1528239:1546885154688515488731989Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein3e-1584