Pre_GI: BLASTP Hits

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Query: NC_017517:898771:909041 Neisseria meningitidis M01-240355 chromosome, complete genome

Start: 909041, End: 909157, Length: 117

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017515:1402218:140962614096261409742117Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein2e-1477.4
NC_003116:1018813:103038810303881030504117Neisseria meningitidis Z2491, complete genomehypothetical protein2e-1477.4
NC_017516:1408000:141525314152531415369117Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein3e-1270.5