Pre_GI: BLASTP Hits

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Query: NC_017517:1915842:1927283 Neisseria meningitidis M01-240355 chromosome, complete genome

Start: 1927283, End: 1927534, Length: 252

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013016:354000:363521363521363940420Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein3e-38156
NC_017501:1913360:192533119253311925750420Neisseria meningitidis 8013, complete genomehypothetical protein2e-38157
NC_008767:877904:888453888453888872420Neisseria meningitidis FAM18, complete genomeputative integral membrane protein2e-2098.2