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Query: NC_017517:1377617:1377617 Neisseria meningitidis M01-240355 chromosome, complete genome

Start: 1377617, End: 1378171, Length: 555

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017505:1338661:134064113406411341195555Neisseria meningitidis alpha710 chromosome, complete genomeputative membrane lipoprotein9e-59226
NC_013016:1257942:125997512599751260529555Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein9e-59226
NC_017516:917817:936995936995937549555Neisseria meningitidis H44/76 chromosome, complete genomeputative lipoprotein1e-57222
NC_002946:618439:638163638163638717555Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein1e-56218
NC_011035:1033942:103394210339421034559618Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeMembrane lipoprotein2e-56218