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Query: NC_017516:1613762:1618621 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 1618621, End: 1618950, Length: 330

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017515:1601954:160681216068121607141330Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein1e-57221
NC_003112:673772:685636685636685965330Neisseria meningitidis MC58, complete genomehypothetical protein1e-57221
NC_017513:618500:638348638348638677330Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein9e-57218
NC_010120:609323:627502627502627831330Neisseria meningitidis 053442, complete genomeconserved hypothetical protein9e-57218
NC_008767:1829500:184147018414701841805336Neisseria meningitidis FAM18, complete genomehypothetical protein6e-37152
NC_017511:1257663:126779712677971268132336Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein5e-35146
NC_017501:1680075:169202816920281692363336Neisseria meningitidis 8013, complete genomehypothetical protein5e-35146
NC_011035:1348659:135941913594191359754336Neisseria gonorrhoeae NCCP11945 chromosome, complete genomehypothetical protein5e-35146
NC_014752:197000:197000197000197335336Neisseria lactamica ST-640, complete genomehypothetical protein6e-35145