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Query: NC_017516:1613762:1618235 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 1618235, End: 1618495, Length: 261

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017517:703811:715921715921716271351Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein1e-43175
NC_017505:670919:687943687943688293351Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein1e-43175
NC_017513:618500:638803638803639063261Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein6e-43172
NC_003112:673772:686091686091686351261Neisseria meningitidis MC58, complete genomehypothetical protein6e-43172
NC_017515:1601954:160642616064261606686261Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein1e-42171
NC_008767:613394:630897630897631076180Neisseria meningitidis FAM18, complete genomeconserved hypothetical protein (fragment)2e-27120