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Query: NC_017516:123618:146160 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 146160, End: 146309, Length: 150

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017514:2096452:212238921223892122538150Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein3e-22103
NC_002946:1786000:181222218122221812371150Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein2e-1890.9
NC_014752:834616:8362878362878375911305Neisseria lactamica ST-640, complete genomehypothetical protein1e-1168.6