Pre_GI: BLASTP Hits

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Query: NC_017516:123618:130562 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 130562, End: 130879, Length: 318

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017501:121902:128780128780129157378Neisseria meningitidis 8013, complete genomeputative DNA-binding protein8e-55211
NC_013016:2041890:205662520566252057002378Neisseria meningitidis alpha14 chromosome, complete genomeputative transcriptional regulator8e-55211
NC_017513:115870:122809122809123126318Neisseria meningitidis G2136 chromosome, complete genomeDNA-binding protein1e-54211
NC_010120:2055803:207053920705392070838300Neisseria meningitidis 053442, complete genomeconserved hypothetical protein9e-51198
NC_017512:2116295:213102621310262131406381Neisseria meningitidis WUE 2594, complete genomeputative DNA-binding protein9e-45178