Pre_GI: BLASTP Hits

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Query: NC_017516:123618:129832 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 129832, End: 130383, Length: 552

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017501:121902:128110128110128661552Neisseria meningitidis 8013, complete genomehypothetical protein7e-101365
NC_017512:2116295:213152521315252132076552Neisseria meningitidis WUE 2594, complete genomehypothetical protein3e-98357
NC_010120:2055803:207103520710352071586552Neisseria meningitidis 053442, complete genomeintegral membrane protein3e-98357
NC_017513:115870:122238122238122630393Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein9e-53206
NC_013016:2041890:205712120571212057513393Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein9e-53206