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Query: NC_017516:123618:129117 Neisseria meningitidis H44/76 chromosome, complete genome

Start: 129117, End: 129812, Length: 696

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010120:2055803:207160620716062072301696Neisseria meningitidis 053442, complete genomeconserved hypothetical protein2e-136484
NC_017501:121902:127395127395128090696Neisseria meningitidis 8013, complete genomehypothetical protein1e-136484
NC_013016:2041890:205769320576932058388696Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein2e-136484
NC_017513:115870:121363121363122058696Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein6e-137486
NC_017512:2116295:213209621320962132791696Neisseria meningitidis WUE 2594, complete genomehypothetical protein1e-136484