Pre_GI: BLASTP Hits

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Query: NC_017514:1721416:1747028 Neisseria meningitidis M01-240149 chromosome, complete genome

Start: 1747028, End: 1747633, Length: 606

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017518:1843705:190041919004191901402984Neisseria meningitidis NZ-05/33 chromosome, complete genomeinitiator repB protein family2e-115414
NC_017516:1755500:178139217813921782294903Neisseria meningitidis H44/76 chromosome, complete genomeinitiator repB protein family2e-115414
NC_017515:1744500:177710717771071778090984Neisseria meningitidis M04-240196 chromosome, complete genomeinitiator repB protein family2e-115414
NC_017505:497603:520179520179521162984Neisseria meningitidis alpha710 chromosome, complete genomereplication protein2e-115414
NC_003112:498465:518212518212519195984Neisseria meningitidis MC58, complete genomereplication protein2e-115414
NC_017501:543000:543148543148544050903Neisseria meningitidis 8013, complete genomeputative replication initiation protein9e-112402
NC_017517:527687:551879551879552862984Neisseria meningitidis M01-240355 chromosome, complete genomeinitiator repB protein family1e-110398
NC_009651:19909:289402894029788849Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN5,replication initiator protein1e-1273.2
NC_013016:354000:360247360247360582336Neisseria meningitidis alpha14 chromosome, complete genomeputative initiator RepB protein1e-1066.2
NC_017501:1913360:192871219287121929029318Neisseria meningitidis 8013, complete genome2e-1065.5