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Query: NC_017514:1721416:1733744 Neisseria meningitidis M01-240149 chromosome, complete genome

Start: 1733744, End: 1734322, Length: 579

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017501:543000:5458665458665515895724Neisseria meningitidis 8013, complete genomehemagglutinin/hemolysin-related protein TpsA13e-85313
NC_017505:497603:531688531688532293606Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein2e-84311
NC_017518:1843705:1882025188202518836951671Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein2e-0652
NC_017514:446616:4746014746014764061806Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein2e-0652
NC_017505:1783476:1820936182093618228461911Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein2e-0652
NC_017515:1744500:1825933182593318284672535Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein4e-0651.2