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Query: NC_017514:1568591:1581523 Neisseria meningitidis M01-240149 chromosome, complete genome

Start: 1581523, End: 1582275, Length: 753

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017501:1680075:1698173169817317005722400Neisseria meningitidis 8013, complete genomeputative MafB-related protein3e-137487
NC_017517:703811:7062827062827086812400Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein3e-137487
NC_017518:743955:752747752747753499753Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein4e-136483
NC_017513:618500:627304627304628056753Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein4e-136483
NC_014752:834616:8549188549188638818964Neisseria lactamica ST-640, complete genomelarge surface adhesin7e-26117
NC_014147:765941:7792147792147802241011Moraxella catarrhalis RH4 chromosome, complete genomehemolysin2e-1789.7
NC_014147:765941:776968776968777879912Moraxella catarrhalis RH4 chromosome, complete genomehypothetical protein5e-1374.7