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Query: NC_017512:2209000:2217556 Neisseria meningitidis WUE 2594, complete genome

Start: 2217556, End: 2217873, Length: 318

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008767:2160000:217165521716552171972318Neisseria meningitidis FAM18, complete genomehypothetical protein1e-56218
NC_017516:2220000:223106722310672231384318Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein4e-56216
NC_011035:1908000:191757319175731917776204Neisseria gonorrhoeae NCCP11945 chromosome, complete genomehypothetical protein8e-27119
NC_002946:1902642:191483219148321915035204Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein8e-27119
NC_017511:1812000:182141618214161821619204Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein2e-26117