Pre_GI: BLASTP Hits

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Query: NC_017512:2209000:2209317 Neisseria meningitidis WUE 2594, complete genome

Start: 2209317, End: 2209766, Length: 450

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008767:2160000:216289121628912163340450Neisseria meningitidis FAM18, complete genomeputative integral membrane protein8e-57218
NC_017516:2220000:222283022228302223279450Neisseria meningitidis H44/76 chromosome, complete genomeDoxX family protein2e-56217
NC_011035:1908000:191071919107191911168450Neisseria gonorrhoeae NCCP11945 chromosome, complete genomemembrane protein3e-56216
NC_002946:1902642:192147019214701921919450Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein2e-55213
NC_017511:1812000:181456218145621815011450Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein3e-55213
NC_012913:1041969:105898910589891059429441Aggregatibacter aphrophilus NJ8700, complete genomeintegral membrane protein5e-28123
NC_012968:1191037:119399611939961194520525Methylotenera mobilis JLW8, complete genomeDoxX family protein2e-1270.9