Pre_GI: BLASTP Hits

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Query: NC_017512:2161000:2168383 Neisseria meningitidis WUE 2594, complete genome

Start: 2168383, End: 2169246, Length: 864

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014532:1579419:159131215913121592256945Halomonas elongata DSM 2581, complete genomeputative glycosyl transferase5e-0962
NC_017323:689512:7004047004047026652262Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequencecapsular polysaccharide biosynthesis protein2e-0756.6