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Query: NC_017512:1264542:1278621 Neisseria meningitidis WUE 2594, complete genome

Start: 1278621, End: 1278749, Length: 129

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013016:1257942:127454212745421274751210Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein1e-0755.5
NC_017505:1338661:135477413547741354902129Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein4e-0753.1
NC_017516:917817:923365923365923574210Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein9e-0855.5
NC_017517:1377617:139302013930201393139120Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein2e-0651.2
NC_003116:1488576:150265515026551502783129Neisseria meningitidis Z2491, complete genomehypothetical protein4e-0753.1