Pre_GI: BLASTP Hits

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Query: NC_017512:1264542:1268500 Neisseria meningitidis WUE 2594, complete genome

Start: 1268500, End: 1269045, Length: 546

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003116:1488576:149253414925341493079546Neisseria meningitidis Z2491, complete genomehypothetical protein6e-95345
NC_013016:1257942:126457112645711265116546Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein2e-92338
NC_017517:1377617:138227513822751382799525Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein7e-91332
NC_002946:618439:633541633541634086546Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein1e-90332
NC_017511:950411:954425954425954949525Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein6e-87319
NC_011035:1033942:103859510385951039119525Neisseria gonorrhoeae NCCP11945 chromosome, complete genomehypothetical protein6e-87319