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Query: NC_017501:1633436:1652100 Neisseria meningitidis 8013, complete genome

Start: 1652100, End: 1652540, Length: 441

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003116:867943:869249869249869689441Neisseria meningitidis Z2491, complete genometranscriptional regulator6e-73272
NC_017518:795113:796419796419796859441Neisseria meningitidis NZ-05/33 chromosome, complete genomeputative transcriptional regulator FolI4e-72269
NC_017514:1520245:153798615379861538426441Neisseria meningitidis M01-240149 chromosome, complete genomeputative transcriptional regulator FolI4e-72269
NC_017505:721395:722701722701723141441Neisseria meningitidis alpha710 chromosome, complete genomeputative transcriptional regulator4e-72269
NC_017517:749031:750336750336750782447Neisseria meningitidis M01-240355 chromosome, complete genomeputative transcriptional regulator FolI6e-68255
NC_003112:719490:720795720795721241447Neisseria meningitidis MC58, complete genomefolI protein9e-68254
NC_017515:1555500:157209915720991572545447Neisseria meningitidis M04-240196 chromosome, complete genomeputative transcriptional regulator FolI4e-66249