Some Help

Query: NC_017379:996500:999258 Helicobacter pylori Puno135 chromosome, complete genome

Start: 999258, End: 1001108, Length: 1851

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017355:997089:1000599100059910022631665Helicobacter pylori v225d chromosome, complete genomehypothetical protein01008
NC_017378:986611:9893459893459904511107Helicobacter pylori Puno120 chromosome, complete genomehypothetical protein0652
NC_012973:967380:971047971047971931885Helicobacter pylori B38 chromosome, complete genome2e-148526
NC_017378:986611:990454990454991200747Helicobacter pylori Puno120 chromosome, complete genomehypothetical protein5e-141501
NC_000915:1044000:104871410487141049427714Helicobacter pylori 26695, complete genomehypothetical protein5e-105382
NC_018939:1044000:104873210487321049427696Helicobacter pylori 26695 chromosome, complete genomehypothetical protein2e-101370
NC_018939:454000:473403473403474071669Helicobacter pylori 26695 chromosome, complete genomehypothetical protein3e-75283
NC_000915:453958:473368473368474066699Helicobacter pylori 26695, complete genomehypothetical protein3e-75283
NC_017362:992293:996466996466996900435Helicobacter pylori Lithuania75 chromosome, complete genomehypothetical protein3e-75283
NC_012973:967380:970520970520970966447Helicobacter pylori B38 chromosome, complete genome3e-59230
NC_017355:997089:100218710021871002456270Helicobacter pylori v225d chromosome, complete genomehypothetical protein1e-35151
NC_010170:4463000:4499522449952245012851764Bordetella petrii, complete genomehypothetical protein4e-33143
NC_017362:992293:996972996972997208237Helicobacter pylori Lithuania75 chromosome, complete genomehypothetical protein1e-29131
NC_010002:4572573:4595113459511345961951083Delftia acidovorans SPH-1, complete genomehypothetical protein1e-29131
NC_009092:1874888:191257119125711913092522Shewanella loihica PV-4, complete genomehypothetical protein6e-1273.2