Pre_GI: BLASTP Hits

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Query: NC_017379:505350:520614 Helicobacter pylori Puno135 chromosome, complete genome

Start: 520614, End: 521372, Length: 759

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017378:502806:517799517799518557759Helicobacter pylori Puno120 chromosome, complete genomecag pathogenicity island protein (cagV, cag10)5e-144509
NC_017359:813500:816258816258817016759Helicobacter pylori Sat464 chromosome, complete genomecag pathogenicity island protein (cagV, cag10)5e-144509
NC_017355:493237:508436508436509194759Helicobacter pylori v225d chromosome, complete genomecag pathogenicity island protein (cagV)5e-144509
NC_010698:819912:828660828660829418759Helicobacter pylori Shi470, complete genomecag pathogenicity island protein V5e-144509
NC_017358:563336:577737577737578495759Helicobacter pylori Cuz20 chromosome, complete genomecag pathogenicity island protein V4e-143506
NC_014256:683384:686072686072686830759Helicobacter pylori B8 chromosome, complete genomecag pathogenicity island protein V1e-142505
NC_014555:502151:517022517022517780759Helicobacter pylori PeCan4 chromosome, complete genomecag island protein1e-142505
NC_017063:800156:815831815831816589759Helicobacter pylori ELS37 chromosome, complete genomecag pathogenicity island protein V3e-142504
NC_017376:538000:554451554451555209759Helicobacter pylori SNT49 chromosome, complete genomecag island protein2e-142504
NC_011333:514464:529735529735530493759Helicobacter pylori G27 chromosome, complete genomecag pathogenicity island protein V2e-142504
NC_014560:518582:521298521298522056759Helicobacter pylori SJM180 chromosome, complete genomecag pathogenicity island protein V2e-142504
NC_017366:535188:550698550698551456759Helicobacter pylori F32, complete genomecag pathogenicity island protein2e-142504
NC_011498:553525:568917568917569675759Helicobacter pylori P12, complete genomecag pathogenicity island protein V2e-142504
NC_008086:513407:529409529409530167759Helicobacter pylori HPAG1, complete genomecag pathogenicity island protein V2e-142504
NC_017368:852490:855066855066855824759Helicobacter pylori F16, complete genomecag pathogenicity island protein1e-142504
NC_000915:547783:563237563237563995759Helicobacter pylori 26695, complete genomecag pathogenicity island protein (cag10)6e-142503
NC_018939:547793:563247563247564005759Helicobacter pylori 26695 chromosome, complete genomecag pathogenicity island protein (cag10)6e-142503
NC_017362:506950:522279522279523037759Helicobacter pylori Lithuania75 chromosome, complete genomecag pathogenicity island protein V4e-142503
NC_017372:855384:858071858071858829759Helicobacter pylori India7 chromosome, complete genomecag pathogenicity island protein V4e-142503
NC_017360:1052473:105535610553561056114759Helicobacter pylori 35A chromosome, complete genomecag pathogenicity island protein4e-142503
NC_017365:848500:851257851257852015759Helicobacter pylori F30, complete genomecag pathogenicity island protein4e-142503
NC_017367:562918:577819577819578577759Helicobacter pylori F57, complete genomecag pathogenicity island protein4e-142503
NC_017354:848500:851272851272852030759Helicobacter pylori 52 chromosome, complete genomecag pathogenicity island protein V4e-142503
NC_000921:511642:526781526781527539759Helicobacter pylori J99, complete genomecag island protein1e-141502
NC_017357:495213:512300512300513058759Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein1e-141502
NC_017374:498588:511321511321512079759Helicobacter pylori 2017 chromosome, complete genomeInner membrane protein1e-141502
NC_017381:500699:513421513421514179759Helicobacter pylori 2018 chromosome, complete genomeinner membrane protein1e-141502
NC_017375:872478:875058875058875816759Helicobacter pylori 83 chromosome, complete genomecag pathogenicity island protein9e-142502
NC_017371:530673:546163546163546921759Helicobacter pylori Gambia94/24 chromosome, complete genomecag pathogenicity island protein V3e-141500
NC_012912:1701231:170212117021211702804684Dickeya zeae Ech1591, complete genomeVirB8 family protein1e-0860.5
NC_014500:3097362:315295931529593153642684Dickeya dadantii 3937 chromosome, complete genomeInner membrane protein forms channel for type IV secretion of T-DNA complex (VirB8)3e-0858.9