Pre_GI: BLASTP Hits

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Query: NC_017379:1035464:1072519 Helicobacter pylori Puno135 chromosome, complete genome

Start: 1072519, End: 1073688, Length: 1170

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017357:973392:9970029970029981711170Helicobacter pylori 908 chromosome, complete genometype1 capsular polysaccharide biosynthesis protein J0781
NC_014624:3538094:3556097355609735572301134Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein6e-82304
NC_014638:1509637:1527051152705115282411191Bifidobacterium bifidum PRL2010 chromosome, complete genomeglycosyltransferase5e-68258
NC_021184:2013058:2032061203206120332511191Desulfotomaculum gibsoniae DSM 7213, complete genomeglycosyltransferase1e-1377.8
NC_008541:1503835:1507789150778915089851197Arthrobacter sp. FB24 chromosome 1, complete sequenceglycosyl transferase, group 12e-1377.4
NC_012803:691215:7245097245097257291221Micrococcus luteus NCTC 2665, complete genomeglycosyltransferase4e-1376.3
NC_014550:3839389:1146511465126401176Arthrobacter arilaitensis Re117, complete genomeputative group 1 glycosyl transferase5e-1375.9
NC_014550:7560:1146511465126401176Arthrobacter arilaitensis Re117, complete genomeputative group 1 glycosyl transferase5e-1375.9
NC_014958:3094500:3108903310890331100511149Deinococcus maricopensis DSM 21211 chromosome, complete genomegroup 1 glycosyl transferase8e-1375.1
NC_007645:5397526:5414719541471954157771059Hahella chejuensis KCTC 2396, complete genomeGlycosyltransferase4e-1169.7
NC_009051:165102:1651021651021665321431Methanoculleus marisnigri JR1, complete genomeglycosyl transferase, group 17e-1168.6
NC_015690:632565:6452676452676464151149Paenibacillus mucilaginosus KNP414 chromosome, complete genomegroup 1 glycosyl transferase8e-1168.6
NC_007503:919808:9201219201219212631143Carboxydothermus hydrogenoformans Z-2901, complete genomeglycosyl transferase, group 1 family1e-1068.2
NC_006177:2883476:2909176290917629102611086Symbiobacterium thermophilum IAM 14863, complete genomeputative glycosyl transferase4e-1066.2
NC_019968:891904:9058139058139069131101Prevotella dentalis DSM 3688 chromosome 2, complete sequenceglycosyltransferase6e-1065.9
NC_014355:2321957:2337284233728423385191236Candidatus Nitrospira defluvii, complete genomeputative glycosyl transferase, group 16e-1065.9
NC_014219:3254268:3275867327586732769611095Bacillus selenitireducens MLS10 chromosome, complete genomeglycosyl transferase group 11e-0964.3
NC_009464:2523092:2552912255291225540721161Uncultured methanogenic archaeon RC-I, complete genomeglycosyltransferase (group 1)2e-0963.9
NC_014153:2282725:2292111229211122932861176Thiomonas intermedia K12 chromosome, complete genomeglycosyl transferase group 15e-0962.8
NC_019974:2960872:2976680297668029777831104Natronococcus occultus SP4, complete genomeglycosyltransferase5e-0962.4
NC_016148:1877711:1886949188694918880251077Thermovirga lienii DSM 17291 chromosome, complete genomegroup 1 glycosyl transferase1e-0861.2
NC_005140:444353:4587264587264597661041Vibrio vulnificus YJ016 chromosome II, complete sequenceputative lipopolysaccharide biosynthesis protein1e-0861.2
NC_013204:2826500:2861584286158428626391056Eggerthella lenta DSM 2243, complete genomeglycosyl transferase group 12e-0860.8
NC_014966:431342:4466904466904477301041Vibrio vulnificus MO6-24/O chromosome II, complete sequenceglycosyltransferase3e-0860.1
NC_009483:2993818:3000629300062930017501122Geobacter uraniireducens Rf4 chromosome, complete genomegroup 1 glycosyl transferase3e-0860.1
NC_014355:2635500:2647792264779226489161125Candidatus Nitrospira defluvii, complete genomeglycosyl transferase group 1 protein2e-0860.1
NC_004460:1718088:1733425173342517344651041Vibrio vulnificus CMCP6 chromosome II, complete sequenceGlycosyltransferase4e-0859.7
NC_000916:251000:2675232675232687251203Methanothermobacter thermautotrophicus str. Delta H, completeLPS biosynthesis RfbU related protein7e-0858.9
NC_018876:703633:7134267134267145531128Methanolobus psychrophilus R15 chromosome, complete genomeglycosyl transferase, group 11e-0758.2
NC_015978:996933:1016396101639610176071212Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein2e-0757.4
NC_007907:3722500:3749265374926537503771113Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-0757
NC_007413:3168931:3189341318934131906061266Anabaena variabilis ATCC 29413, complete genomeGlycosyl transferase, group 12e-0757
NC_019967:29448:4827448274494581185Natrinema pellirubrum DSM 15624 plasmid pNATPE01, completeglycosyltransferase2e-0757
NS_000195:1785910:1814801181480118159731173Candidatus Cloacamonas acidaminovoransputative glycosyltansferase3e-0756.6
NC_014828:1795781:1795781179578117969141134Ethanoligenens harbinense YUAN-3 chromosome, complete genomeglycosyl transferase group 13e-0756.6
NC_000917:40111:4796647966516073642Archaeoglobus fulgidus DSM 4304, complete genomemannosyltransferase A (mtfA)7e-0755.5
NC_020389:2245368:2261555226155522626611107Methanosarcina mazei Tuc01, complete genomeglycosyl transferase, group 1 family protein9e-0755.1
NC_003901:2626426:2643372264337226444781107Methanosarcina mazei Go1, complete genometransposase1e-0654.7
NC_012804:1:2029520295214731179Thermococcus gammatolerans EJ3, complete genomeGlycosyltransferase, family 11e-0654.7
NC_003364:225500:2421682421682432501083Pyrobaculum aerophilum str. IM2, complete genomeglycosyltransferase (type 1)2e-0654.3
NC_012489:652319:6609456609456620271083Gemmatimonas aurantiaca T-27, complete genomeputative glycosyltransferase2e-0654.3
NC_009454:358044:3697703697703708941125Pelotomaculum thermopropionicum SI, complete genomeglycosyltransferase2e-0653.9
NC_012883:1817358:1844587184458718457951209Thermococcus sibiricus MM 739, complete genomeGlycosyl transferase, group 13e-0653.5
NC_015578:2026741:206950820695082070413906Treponema primitia ZAS-2 chromosome, complete genome3e-0653.5
NC_011027:1971580:1998239199823919993841146Chlorobaculum parvum NCIB 8327, complete genomeglycosyl transferase group 15e-0652.8
NC_008701:1363665:1363665136366513647591095Pyrobaculum islandicum DSM 4184, complete genomeglycosyl transferase, group 15e-0652.4
NC_012793:3275751:3291318329131832924511134Geobacillus sp. WCH70, complete genomeglycosyl transferase group 15e-0652.4
NC_015216:1278706:1319070131907013202091140Methanobacterium sp. AL-21 chromosome, complete genomegroup 1 glycosyl transferase5e-0652.4
NC_016631:3114000:3149900314990031510901191Granulicella mallensis MP5ACTX8 chromosome, complete genomegroup 1 glycosyl transferase6e-0652.4
NC_007955:742834:7522887522887534091122Methanococcoides burtonii DSM 6242, complete genomeglycosyl transferase, group 16e-0652.4
NC_015311:1612366:1628609162860916297451137Prevotella denticola F0289 chromosome, complete genomeglycosyltransferase group 1 family protein6e-0652.4