Pre_GI: BLASTP Hits

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Query: NC_017379:1035464:1048353 Helicobacter pylori Puno135 chromosome, complete genome

Start: 1048353, End: 1049618, Length: 1266

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014555:1526775:1547587154758715488521266Helicobacter pylori PeCan4 chromosome, complete genomeVirB10 type IV secretion protein0808
NC_011498:448000:4809874809874822521266Helicobacter pylori P12, complete genomeVirB10 type IV secretion protein0798
NC_017361:1528239:1539861153986115411231263Helicobacter pylori SouthAfrica7 chromosome, complete genomeVirB10 type IV secretion protein0786
NC_017367:278916:2946922946922959271236Helicobacter pylori F57, complete genomeComB3 protein6e-176617
NC_011333:1040192:1056088105608810573231236Helicobacter pylori G27 chromosome, complete genomecompetence protein6e-176617
NC_017376:57500:8901489014902491236Helicobacter pylori SNT49 chromosome, complete genomecompetence protein4e-175614
NC_017361:930280:9621619621619633961236Helicobacter pylori SouthAfrica7 chromosome, complete genomecompetence protein3e-173608
NC_017358:220900:2382162382162394511236Helicobacter pylori Cuz20 chromosome, complete genomecompetence protein2e-173608
NC_010698:870312:9022439022439034781236Helicobacter pylori Shi470, complete genomeComB3 protein5e-173607
NC_017371:1030148:1039276103927610405231248Helicobacter pylori Gambia94/24 chromosome, complete genomecompetence protein5e-170597
NC_014256:448710:462746462746463504759Helicobacter pylori B8 chromosome, complete genomeDNA transformation compentancy4e-132471
NC_011498:1391788:1402591140259114038291239Helicobacter pylori P12, complete genomeVirB10 type IV secretion protein7e-83308
NC_017063:834674:8455588455588467661209Helicobacter pylori ELS37 chromosome, complete genomeVirB10 type IV secretion protein7e-83308
NC_017375:77142:9799997999992011203Helicobacter pylori 83 chromosome, complete genomeconjugal transfer protein TrbI1e-82307
NC_017371:1470582:1512192151219215134001209Helicobacter pylori Gambia94/24 chromosome, complete genomeVirB10 type IV secretion protein5e-82305
NC_014256:485969:5179145179145191221209Helicobacter pylori B8 chromosome, complete genometype IV secretion system protein VirB103e-82305
NC_017372:748097:7891127891127903141203Helicobacter pylori India7 chromosome, complete genometype IV secretion system protein VirB101e-81304
NC_005090:1033746:1050597105059710517001104Wolinella succinogenes DSM 1740, complete genomeCOMB32e-70266
NC_014256:448710:463629463629464009381Helicobacter pylori B8 chromosome, complete genomeDNA transformation compentancy4e-69262
NC_000921:1007519:102149810214981022304807Helicobacter pylori J99, complete genomehypothetical protein2e-25117
NC_011666:1601983:1601983160198316031911209Methylocella silvestris BL2, complete genomeconjugation TrbI family protein3e-21103
NC_004463:1772541:1776632177663217778341203Bradyrhizobium japonicum USDA 110, complete genomeconjugal transfer protein8e-21102
NC_016814:18000:3574535745369561212Sinorhizobium fredii HH103 plasmid pSfHH103c complete sequenceType IV secretion system protein virB103e-1996.7
NC_017249:2109843:2116976211697621181871212Bradyrhizobium japonicum USDA 6, complete genomeconjugal transfer protein8e-1995.1
NC_009720:3210387:3212089321208932132941206Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein4e-1893.2
NC_014834:614890:6214596214596226701212Rhodopseudomonas palustris DX-1 chromosome, complete genomeconjugation TrbI family protein5e-1892.8
NC_009720:813157:8273798273798285841206Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein9e-1891.7
NC_009485:8138314:8141321814132181425201200Bradyrhizobium sp. BTAi1 chromosome, complete genomeconjugal transfer protein TrbI2e-1790.5
NC_013422:1755875:1793675179367517949941320Halothiobacillus neapolitanus c2, complete genomeconjugation TrbI family protein3e-1789.7
NC_014834:959986:9842109842109853851176Rhodopseudomonas palustris DX-1 chromosome, complete genomeconjugation TrbI family protein3e-1789.7
NC_015186:491930:4949124949124961711260Acidiphilium multivorum AIU301, complete genomeconjugal transfer protein TrbI6e-1789
NC_010338:4148667:4155362415536241565971236Caulobacter sp. K31, complete genomeconjugation TrbI family protein7e-1789
NC_006371:1743982:1756319175631917574551137Photobacterium profundum SS9 chromosome 2, complete sequencehypothetical protein TrbI1e-1688.2
NC_007925:3911323:3925335392533539265701236Rhodopseudomonas palustris BisB18, complete genomeconjugation TrbI-like protein1e-1688.2
NC_015381:2859000:2871875287187528731911317Burkholderia gladioli BSR3 chromosome 1, complete sequenceconjugation TrbI family protein2e-1687.4
NC_009668:529175:5418135418135429401128Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequenceconjugation TrbI family protein4e-1686.3
NC_015186:2839668:2855282285528228565591278Acidiphilium multivorum AIU301, complete genomeconjugal transfer protein TrbI5e-1685.9
NC_009720:3317642:3333207333320733344631257Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein5e-1685.9
NC_010725:3315007:3319252331925233205171266Methylobacterium populi BJ001, complete genomeconjugation TrbI family protein6e-1685.5
NC_008577:1489643:1501877150187715031571281Shewanella sp. ANA-3 chromosome 1, complete sequenceconjugation TrbI family protein1e-1584.7
NC_007798:652317:6615286615286629011374Neorickettsia sennetsu str. Miyayama, complete genometype IV secretion system protein VirB102e-1584.3
NC_014834:3472000:3498618349861834998261209Rhodopseudomonas palustris DX-1 chromosome, complete genomeconjugation TrbI family protein2e-1584.3
NC_008757:77023:8012680126814451320Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, completeconjugation TrbI family protein2e-1584.3
NC_008781:2611702:2647158264715826486301473Polaromonas naphthalenivorans CJ2, complete genomeconjugation TrbI family protein2e-1584.3
NC_008254:534590:5542065542065554051200Mesorhizobium sp. BNC1, complete genomeconjugation TrbI-like protein1e-1584.3
NC_015422:1643000:1657600165760016588861287Alicycliphilus denitrificans K601 chromosome, complete genomeconjugation TrbI family protein2e-1584
NC_010170:4800000:4887431488743148886841254Bordetella petrii, complete genomeconjugal transfer protein TrbI2e-1584
NC_009656:3817261:3832621383262138338981278Pseudomonas aeruginosa PA7 chromosome, complete genomeconjugation TrbI family protein3e-1583.6
NC_009720:4406991:4419880441988044211241245Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein3e-1583.6
NC_011992:1381843:1384940138494013862231284Acidovorax ebreus TPSY, complete genomeconjugation TrbI family protein3e-1583.2
NC_007950:206474:2077542077542090221269Polaromonas sp. JS666 plasmid 2, complete sequenceconjugation TrbI-like protein8e-1582
NC_009720:750612:7800217800217811721152Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein8e-1582
NC_006831:4500:1563515635169751341Ehrlichia ruminantium str. Gardel, complete genomeVirB10 protein1e-1481.3
NC_005295:21995:3463334633359791347Ehrlichia ruminantium str. Welgevonden, complete genometype IV secretion system protein VirB101e-1481.3
NC_010002:2933909:2959059295905929603271269Delftia acidovorans SPH-1, complete genomeconjugation TrbI family protein3e-1480.1
NC_002978:4973:5784578472441461Wolbachia endosymbiont of Drosophila melanogaster, complete genometype IV secretion system protein VirB108e-1478.6
NC_014500:894136:9000959000959013391245Dickeya dadantii 3937 chromosome, complete genomeConjugative transfer protein TrbI7e-1478.6
NC_012416:4973:5784578472801497Wolbachia sp. wRi, complete genometype IV secretion system protein VirB101e-1378.2
NC_012912:1295653:1317386131738613186241239Dickeya zeae Ech1591, complete genomeconjugation TrbI family protein1e-1378.2
NC_009720:670853:6772356772356784821248Xanthobacter autotrophicus Py2, complete genomeconjugation TrbI family protein4e-1376.3
NC_007797:1451804:1463517146351714648211305Anaplasma phagocytophilum HZ, complete genometype IV secretion system protein VirB105e-1376.3
NC_014414:2569494:2569494256949425707501257Parvularcula bermudensis HTCC2503 chromosome, complete genomeconjugal transfer protein trbI2e-1273.9
NC_015410:3209954:3213749321374932150141266Pseudomonas mendocina NK-01 chromosome, complete genomeconjugation TrbI family protein3e-1273.2
NC_015593:2914384:2917552291755229188531302Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeconjugation TrbI family protein5e-1272.8
NC_010125:2813653:2829722282972228308941173Gluconacetobacter diazotrophicus PAl 5, complete genomeputative conjugation TrbI-like protein5e-1272.8
NC_015850:110364:1668211668211681371317Acidithiobacillus caldus SM-1 chromosome, complete genomeconjugation TrbI family protein5e-1272.8
NC_002678:5714000:571716757171675717682516Mesorhizobium loti MAFF303099, complete genomesimilar to CONJUGAL TRANSFER PROTEIN TRBI5e-1272.4
NC_015850:2048251:2087030208703020884121383Acidithiobacillus caldus SM-1 chromosome, complete genomehypothetical protein6e-1272.4
NC_020301:1449616:1448453144845314496191167Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genometype IV secretion system protein VirB107e-1272.4
NC_014006:2932959:2951831295183129530931263Sphingobium japonicum UT26S chromosome 1, complete genomeconjugal transfer protein TrbI1e-1171.6
NC_010125:1011430:1025592102559210267521161Gluconacetobacter diazotrophicus PAl 5, complete genomeputative conjugation TrbI-like protein2e-1170.5
NC_013209:2582878:2587892258789225890611170Acetobacter pasteurianus IFO 3283-01, complete genomeconjugal transfer protein TrbI3e-1170.5
NC_016513:54802:6161261612628831272Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeconjugal transfer protein TrbI/VirB104e-1169.3
NC_004842:1132441:1158480115848011598171338Anaplasma marginale str. St. Maries, complete genomeVirB10 protein1e-1067.8
NC_012026:1135041:1162590116259011639271338Anaplasma marginale str. Florida, complete genomeVirB10 protein (virB10)1e-1067.8
NC_016818:1795576:1824749182474918260441296Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completetype IV secretory pathway, VirB10 component2e-1067.4
NC_016612:5296076:5294782529478252960861305Klebsiella oxytoca KCTC 1686 chromosome, complete genomeconjugation TrbI-like protein2e-1067
NC_014500:1862000:188295018829501883471522Dickeya dadantii 3937 chromosome, complete genomeConjugative transfer protein TrbI2e-1067
NC_015385:1875671:1894075189407518954721398Treponema succinifaciens DSM 2489 chromosome, complete genomeconjugation TrbI family protein3e-1066.6
NC_012912:1701231:1700032170003217012341203Dickeya zeae Ech1591, complete genomeconjugation TrbI family protein4e-1066.2
NC_014500:3097362:3154529315452931557371209Dickeya dadantii 3937 chromosome, complete genomeInner membrane protein forms channel for type IV secretion of T-DNA complex (VirB10)5e-1065.9
NC_016929:825413:8398688398688413161449Rickettsia canadensis str. CA410 chromosome, complete genomehypothetical protein8e-1065.5
NC_020300:1344453:1344453134445313456161164Bartonella australis Aust/NH1, complete genometype IV secretion protein VblB101e-0965.1
NC_015386:107000:1161811161811176171437Treponema succinifaciens DSM 2489 plasmid pTRESU01, completeconjugation TrbI family protein9e-1065.1
NC_011092:76993:9640296402975981197Salmonella enterica subsp. enterica serovar Schwarzengrund strTriI protein1e-0964.7
NC_009879:835227:8497528497528512001449Rickettsia canadensis str. McKiel, complete genomehypothetical protein1e-0964.3
NC_011283:1811000:1842712184271218440191308Klebsiella pneumoniae 342 chromosome, complete genomeconjugation TrbI-like protein2e-0963.5
NC_015593:1587684:1598790159879015998811092Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeconjugation TrbI family protein6e-0962.4
NC_016616:2699350:2740060274006027413851326Dechlorosoma suillum PS chromosome, complete genometype IV secretory pathway, VirB10 component3e-0860.1
NC_003919:3060484:3084400308440030855691170Xanthomonas axonopodis pv. citri str. 306, complete genomeVirB10 protein1e-0758.5
NC_003902:2933121:2948624294862429498051182Xanthomonas campestris pv. campestris str. ATCC 33913, completeVirB10 protein1e-0758.2
NC_007086:1936505:1960414196041419615951182Xanthomonas campestris pv. campestris str. 8004, complete genomeVirB10 protein1e-0758.2
NC_010170:3908500:3923502392350239246351134Bordetella petrii, complete genometype IV secretion system protein VirB102e-0757.4
NC_017271:2935643:2969405296940529706671263Xanthomonas campestris pv. raphani 756C chromosome, completeVirB10 protein3e-0756.6
NC_009254:365812:3718713718713730971227Burkholderia vietnamiensis G4 chromosome 3, complete sequenceconjugation TrbI family protein6e-0755.8
NC_013722:2150882:2162487216248721636621176Xanthomonas albilineans, complete genomeputative virb10 protein8e-0755.5
NC_010515:1124298:1130454113045411316771224Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceconjugation TrbI family protein9e-0755.1
NC_017358:563336:5694205694205718042385Helicobacter pylori Cuz20 chromosome, complete genomecag pathogenicity island protein (cagY, cag7)2e-0653.9
NC_017357:495213:5058855058855075881704Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein3e-0653.5
NC_010688:1908012:1933152193315219343211170Xanthomonas campestris pv. campestris, complete genometype IV secretion system putative channel component VirB43e-0653.5
NC_017381:500699:5071275071275087281602Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein3e-0653.5
NC_017374:498588:5050165050165066171602Helicobacter pylori 2017 chromosome, complete genomecag pathogenicity island protein3e-0653.5
NC_011001:372185:3870723870723882951224Burkholderia cenocepacia J2315 chromosome 2, complete sequenceputative type IV secretion system protein VirB105e-0652.8
NC_017375:872478:8809778809778844533477Helicobacter pylori 83 chromosome, complete genomeDC-EC Repeat superfamily protein4e-0652.8
NC_010943:3034366:3048752304875230500051254Stenotrophomonas maltophilia K279a, complete genomeputative putative bacterial secretion system protein6e-0652.4
NC_011071:2733438:2750462275046227517151254Stenotrophomonas maltophilia R551-3, complete genomeconjugation TrbI family protein6e-0652.4
NC_014923:5765660:5774492577449257756341143Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completeconjugation TrbI family protein7e-0652.4
NC_015675:6276357:6329163632916363303051143Mesorhizobium opportunistum WSM2075 chromosome, complete genomeconjugation TrbI family protein7e-0652.4
NC_019973:5694620:5703452570345257045941143Mesorhizobium australicum WSM2073, complete genometype IV secretory pathway, VirB10 component7e-0652.4
NC_015947:2752450:2768815276881527700861272Burkholderia sp. JV3 chromosome, complete genomeconjugation TrbI family protein7e-0652