Pre_GI: BLASTP Hits

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Query: NC_017376:57500:94832 Helicobacter pylori SNT49 chromosome, complete genome

Start: 94832, End: 97330, Length: 2499

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010698:870312:9080599080599105572499Helicobacter pylori Shi470, complete genomeDNA transfer protein01686
NC_017358:220900:2311372311372336352499Helicobacter pylori Cuz20 chromosome, complete genomeDNA transfer protein01685
NC_017367:278916:2876102876102901082499Helicobacter pylori F57, complete genomeDNA transfer protein01684
NC_017379:1035464:1054184105418410566822499Helicobacter pylori Puno135 chromosome, complete genomeDNA transfer protein01680
NC_017361:930280:9679779679779704752499Helicobacter pylori SouthAfrica7 chromosome, complete genomeDNA transfer protein01665
NC_017371:1030148:1034552103455210364771926Helicobacter pylori Gambia94/24 chromosome, complete genomeDNA transfer protein01277
NC_000921:1007519:1015042101504210164691428Helicobacter pylori J99, complete genomeDNA transfer protein0940
NC_000915:453958:4593334593334617562424Helicobacter pylori 26695, complete genomeVirB4 homolog3e-180632
NC_018939:454000:4593394593394617622424Helicobacter pylori 26695 chromosome, complete genomeVirB4-like protein3e-180632
NC_017361:1528239:1530624153062415330472424Helicobacter pylori SouthAfrica7 chromosome, complete genomeVirB4-like protein2e-179629
NC_014555:1526775:1540379154037915427482370Helicobacter pylori PeCan4 chromosome, complete genomeVirB4-like protein6e-175615
NC_014256:448710:4557574557574579102154Helicobacter pylori B8 chromosome, complete genomeprotein virB44e-155548
NC_011498:448000:4871074871074895292423Helicobacter pylori P12, complete genome1e-129464
NC_014256:485969:5220375220375246132577Helicobacter pylori B8 chromosome, complete genometype IV secretion system protein VirB45e-129462
NC_011498:1391788:1397130139713013997062577Helicobacter pylori P12, complete genomeVirB4 type IV secretion ATPase8e-129461
NC_017371:1470582:1516315151631515188912577Helicobacter pylori Gambia94/24 chromosome, complete genomeVirB4 type IV secretion ATPase2e-128460
NC_017372:748097:7931967931967957782583Helicobacter pylori India7 chromosome, complete genomeVirB4 type IV secretion ATPase9e-125448
NC_005090:1033746:1054413105441310567012289Wolinella succinogenes DSM 1740, complete genomeVIRB4 HOMOLOG1e-101371
NC_000921:1007519:101645710164571016879423Helicobacter pylori J99, complete genomeDNA transfer protein5e-56219
NC_017366:1055319:1061646106164610626621017Helicobacter pylori F32, complete genomevirB4 type IV secretion ATPase1e-50201
NC_017366:1055319:1060409106040910615571149Helicobacter pylori F32, complete genomevirB4 protein9e-46186
NC_015674:1562968:157503915750391575908870Helicobacter bizzozeronii CIII-1, complete genomeATPase4e-41170
NC_007798:758873:7709267709267733372412Neorickettsia sennetsu str. Miyayama, complete genometype IV secretion system protein VirB42e-35151
NC_006831:849500:8734978734978759022406Ehrlichia ruminantium str. Gardel, complete genomeVIRB4 protein precursor1e-32142
NC_006832:853500:8778888778888802932406Ehrlichia ruminantium str. Welgevonden, complete genomeVIRB4 protein precursor2e-32141
NC_005295:873500:8983268983269007282403Ehrlichia ruminantium str. Welgevonden, complete genometype IV secretion system protein VirB42e-32141
NC_007799:474931:4813444813444837462403Ehrlichia chaffeensis str. Arkansas, complete genometype IV secretion system protein VirB43e-32140
NC_007354:756500:7787647787647811662403Ehrlichia canis str. Jake, complete genomeCagE, TrbE, VirB family component of typeIV transporter system7e-32139
NC_009488:1871912:1877046187704618794632418Orientia tsutsugamushi str. Boryong, complete genometype IV secretion system ATPase VirB42e-26121
NC_017028:180219:1951301951301975472418Candidatus Rickettsia amblyommii str. GAT-30V chromosome, completetype IV secretion system ATPase VirB42e-26121
NC_010793:794494:7995707995708019872418Orientia tsutsugamushi str. Ikeda, complete genometype IV secretion system protein VirB43e-26121
NC_009879:107890:1122791122791146962418Rickettsia canadensis str. McKiel, complete genomeType IV secretion/conjugal transfer ATPase, VirB4 family protein4e-26120
NC_016929:109500:1131401131401155572418Rickettsia canadensis str. CA410 chromosome, complete genometype IV secretion system ATPase VirB44e-26120
NC_017044:130000:1353941353941378112418Rickettsia parkeri str. Portsmouth chromosome, complete genometype IV secretion system ATPase VirB41e-24115
NC_010688:1908012:1937139193713919395922454Xanthomonas campestris pv. campestris, complete genometype IV secretion system energizing component VirB41e-24115
NC_017048:452000:4560924560924585092418Rickettsia prowazekii str. GvV257 chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_017049:109000:1122221122221146392418Rickettsia prowazekii str. Chernikova chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_017051:109000:1122251122251146422418Rickettsia prowazekii str. Dachau chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_017056:110500:1140311140311164482418Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_017057:110000:1141481141481165652418Rickettsia prowazekii str. RpGvF24 chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_000963:110500:1140231140231164402418Rickettsia prowazekii str. Madrid E, complete genomeVIRB4 PROTEIN PRECURSOR (virB4)4e-24114
NC_017050:110500:1140211140211164382418Rickettsia prowazekii str. Katsinyian chromosome, complete genometype IV secretion system ATPase VirB44e-24114
NC_017066:33268:4454644546469632418Rickettsia typhi str. TH1527 chromosome, complete genometype IV secretion system ATPase VirB45e-24113
NC_017062:33268:4451344513469302418Rickettsia typhi str. B9991CWPP chromosome, complete genometype IV secretion system ATPase VirB45e-24113
NC_006142:33268:4454644546469632418Rickettsia typhi str. Wilmington, complete genomeVirB4 protein precursor5e-24113
NC_003919:3060484:3079127307912730815802454Xanthomonas axonopodis pv. citri str. 306, complete genomeVirB4 protein9e-24112
NC_015593:1587684:1602558160255816049302373Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completetype IV secretion/conjugal transfer ATPase VirB4 family4e-23110
NC_003902:2933121:2943358294335829458112454Xanthomonas campestris pv. campestris str. ATCC 33913, completeVirB4 protein3e-23110
NC_007086:1936505:1964408196440819668612454Xanthomonas campestris pv. campestris str. 8004, complete genomeVirB4 protein3e-23110
NC_017271:2935643:2964110296411029665512442Xanthomonas campestris pv. raphani 756C chromosome, completeVirB4 protein2e-22108
NC_010943:3034366:3043399304339930458462448Stenotrophomonas maltophilia K279a, complete genomeputative type IV secretion conjugal transfer protein4e-22107
NC_011092:76993:8981789817925672751Salmonella enterica subsp. enterica serovar Schwarzengrund strTriC protein4e-22107
NC_011071:2733438:2745103274510327475502448Stenotrophomonas maltophilia R551-3, complete genometype IV secretion/conjugal transfer ATPase, VirB4 family2e-21105
NC_013722:2150882:2156995215699521594662472Xanthomonas albilineans, complete genomeprobable type iv secretion system protein virb42e-21105
NC_016513:2103958:2125571212557121283422772Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeATPase2e-21105
NC_014801:1:2335823358261262769Campylobacter jejuni subsp. jejuni ICDCCJ07001 plasmid pTet,type IV secretion system protein VirB41e-21105
NC_019973:5694620:5708002570800257103712370Mesorhizobium australicum WSM2073, complete genometype IV secretion/conjugal transfer ATPase, VirB4 family1e-21105
NC_014923:5765660:5779042577904257814112370Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completetype IV secretion/conjugal transfer ATPase, VirB4 family1e-21105
NC_015675:6276357:6333713633371363360822370Mesorhizobium opportunistum WSM2075 chromosome, complete genometype IV secretion/conjugal transfer ATPase, VirB4 family1e-21105
NC_015947:2752450:2763456276345627659032448Burkholderia sp. JV3 chromosome, complete genometype IV secretion/conjugal transfer ATPase, VirB4 family1e-20102
NC_010688:1908012:1944292194429219458151524Xanthomonas campestris pv. campestris, complete genomeVirB4 protein9e-2099.4
NC_013416:939668:9496729496729512131542Aggregatibacter actinomycetemcomitans D11S-1, complete genomeATPase1e-1999.4
NC_010515:1124298:1135251113525111377312481Burkholderia cenocepacia MC0-3 chromosome 2, complete sequencetype IV secretion/conjugal transfer ATPase, VirB4 family5e-1997.1
NC_008543:127675:1494901494901519702481Burkholderia cenocepacia HI2424 chromosome 2, complete sequencetype IV secretion/conjugal transfer ATPase, VirB4 family8e-1996.3
NC_008061:2106848:2117799211779921202792481Burkholderia cenocepacia AU 1054 chromosome 2, complete sequencetype IV secretion/conjugal transfer ATPase, VirB4 family8e-1996.3
NC_016626:1699500:1740570174057017432332664Burkholderia sp. YI23 plasmid byi_1p, complete sequenceType IV secretion system protein VirB42e-1895.5
NC_013592:2968500:2998530299853030012742745Dickeya dadantii Ech586, complete genomeCagE, TrbE, VirB component of type IV transporter system, conserved region3e-1894.7
NC_011001:372185:3810183810183834982481Burkholderia cenocepacia J2315 chromosome 2, complete sequenceputative type IV secretion system protein VirB43e-1894.7
NC_004547:1873390:1874142187414218768892748Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeputative conjugal transfer protein9e-1892.8
NC_014500:3097362:3147941314794131507212781Dickeya dadantii 3937 chromosome, complete genomeATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB4)2e-1791.3
NC_012912:1701231:1705041170504117077882748Dickeya zeae Ech1591, complete genomeCagE TrbE VirB component of type IV transporter system4e-1790.5
NC_009254:365812:3658123658123682802469Burkholderia vietnamiensis G4 chromosome 3, complete sequencetype IV secretion/conjugal transfer ATPase1e-1689
NC_010676:2793237:2793237279323727957022466Burkholderia phytofirmans PsJN chromosome 2, complete sequencetype IV secretion/conjugal transfer ATPase, VirB4 family1e-1689
NC_017047:2079368:2079368207936820821152748Rahnella aquatilis HX2 chromosome, complete genomeputative conjugal transfer protein2e-1688.6
NC_016818:1795576:1829965182996518327122748Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completetype IV secretory pathway, VirB4 component3e-1687.8
NC_020181:473170:4949524949524976902739Enterobacter aerogenes EA1509E, complete genomeATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB4)3e-1687.8
NC_009792:859228:8810098810098837472739Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein3e-1687.8
NC_012731:3411161:3450241345024134529792739Klebsiella pneumoniae NTUH-K2044 chromosome, complete genometype IV secretory pathway VirB3-4 component2e-1585.1
NC_011283:1811000:1847938184793818506852748Klebsiella pneumoniae 342 chromosome, complete genometype IV secretion/conjugal transfer ATPase3e-1584.7
NC_016845:3448881:3469356346935634720942739Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,putative type IV secretory pathway VirB4 component4e-1584
NC_018691:3082000:3099974309997431024242451Alcanivorax dieselolei B5 chromosome, complete genomeATPase5e-1480.5
NC_009656:3817261:3838044383804438404972454Pseudomonas aeruginosa PA7 chromosome, complete genomeconjugal transfer ATPase TrbE9e-1479.7
NC_015381:2859000:2877033287703328794832451Burkholderia gladioli BSR3 chromosome 1, complete sequenceATPase2e-1379
NC_014910:2930860:2930860293086029333192460Alicycliphilus denitrificans BC chromosome, complete genomecage, trbe, virb component of type iv transporter system, conserved region protein2e-1379
NC_015422:1643000:1663023166302316654762454Alicycliphilus denitrificans K601 chromosome, complete genomeCagE, TrbE, VirB component of type IV transporter system, conserved region2e-1378.6
NC_013422:1755875:1755875175587517583342460Halothiobacillus neapolitanus c2, complete genomeCagE, TrbE, VirB component of type IV transporter system, conserved region2e-1378.2
NC_008781:2611702:2636646263664626390902445Polaromonas naphthalenivorans CJ2, complete genomeCagE, TrbE, VirB component of type IV transporter system2e-1378.2
NC_008577:1489643:1495263149526314977132451Shewanella sp. ANA-3 chromosome 1, complete sequenceAAA ATPase2e-1378.2
NC_010170:3908500:3916385391638539188292445Bordetella petrii, complete genometype IV secretion system protein VirB44e-1377.4
NC_015410:3209954:3207528320752832099572430Pseudomonas mendocina NK-01 chromosome, complete genomeconjugal transfer ATPase TrbE4e-1377.4
NC_014500:894136:8941368941368966042469Dickeya dadantii 3937 chromosome, complete genomeConjugative transfer protein TrbE8e-1376.3
NC_003295:2787371:2787371278737127898212451Ralstonia solanacearum GMI1000, complete genomePROBABLE CONJUGAL TRANSFER PROTEIN TRBE8e-1376.3
NC_011206:1293880:1291361129136112938832523Acidithiobacillus ferrooxidans ATCC 53993, complete genomeCagE TrbE VirB component of type IV transporter system1e-1276.3
NC_011985:3869998:3871859387185938742462388Agrobacterium radiobacter K84 chromosome 1, complete genometype IV secretion protein AvhB42e-1275.5
NC_014256:448710:455488455488455736249Helicobacter pylori B8 chromosome, complete genomeDNA transfer protein2e-1275.1
NC_015942:1889421:1889881188988118924332553Acidithiobacillus ferrivorans SS3 chromosome, complete genomeCagE, TrbE, VirB component of type IV transporter system2e-1274.7
NC_015850:2048251:2076658207665820790212364Acidithiobacillus caldus SM-1 chromosome, complete genometype IV secretory pathway VirB4 components-like protein3e-1274.3
NC_014914:127873:1317401317401341452406Taylorella equigenitalis MCE9 chromosome, complete genomeVirB4 ATPase like protein4e-1274.3
NC_010725:3315007:3312572331257233150102439Methylobacterium populi BJ001, complete genomeAAA ATPase6e-1273.6
NC_009720:4406991:4425146442514644275842439Xanthobacter autotrophicus Py2, complete genomeconjugal transfer ATPase TrbE7e-1273.6
NC_009720:670853:6708536708536732822430Xanthobacter autotrophicus Py2, complete genomeconjugal transfer ATPase TrbE1e-1172.8
NC_015556:2265940:2265940226594022683692430Pseudomonas fulva 12-X chromosome, complete genomeCagE, TrbE, VirB component of type IV transporter system, conserved region1e-1172.8
NC_009720:3317642:3338681333868133411192439Xanthobacter autotrophicus Py2, complete genomeconjugal transfer ATPase TrbE1e-1172.4
NC_010338:4148667:4148667414866741511232457Caulobacter sp. K31, complete genomeAAA ATPase4e-1170.9
NC_014834:959986:9776529776529801172466Rhodopseudomonas palustris DX-1 chromosome, complete genomeAAA ATPase4e-1170.9
NC_008686:1439328:1441768144176814442782511Paracoccus denitrificans PD1222 chromosome 1, complete sequenceAAA ATPase5e-1170.5
NC_015385:1875671:1875671187567118782442574Treponema succinifaciens DSM 2489 chromosome, complete genomeAAA ATPase6e-1170.1
NC_010682:1593108:1614519161451916169662448Ralstonia pickettii 12J chromosome 1, complete sequencetype IV secretory pathway VirB4 components-like protein1e-1069.3
NC_010002:2933909:2964490296449029669612472Delftia acidovorans SPH-1, complete genomeAAA ATPase1e-1068.9
NC_011992:3752867:3752867375286737553382472Acidovorax ebreus TPSY, complete genomeCagE TrbE VirB component of type IV transporter system2e-1068.6
NC_009668:529175:5351505351505376602511Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequenceconjugal transfer ATPase TrbE3e-1068.2
NC_006833:976010:9866539866539890072355Wolbachia endosymbiont strain TRS of Brugia malayi, completeType IV secretory pathway, VirB4 components4e-1067.8
NC_015386:125499:1367791367791393552577Treponema succinifaciens DSM 2489 plasmid pTRESU01, completeCagE, TrbE, VirB component of type IV transporter system, conserved region4e-1067.4
NC_010170:4800000:4880844488084448833062463Bordetella petrii, complete genomeconjugal transfer protein TrbE5e-1067.4
NC_009937:4392108:4411982441198244144202439Azorhizobium caulinodans ORS 571, complete genomeATPase precursor8e-1066.6
NC_007925:3911323:3930710393071039331512442Rhodopseudomonas palustris BisB18, complete genomeATPase2e-0965.1
NC_015437:697051:7258257258257282902466Selenomonas sputigena ATCC 35185 chromosome, complete genomeAAA ATPase6e-0963.5
NC_011365:1135750:1136493113649311389192427Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomeconjugal transfer ATPase TrbE6e-0963.5
NC_014834:614890:6148906148906173312442Rhodopseudomonas palustris DX-1 chromosome, complete genometype IV transporter subunit CagE/TrbE/VirB3e-0861.6
NC_008757:77023:97607976071000722466Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, completeType IV secretory pathway VirB4 components-like protein8e-0860.1
NC_012026:960000:9603409603409627692430Anaplasma marginale str. Florida, complete genomeVirB4 protein1e-0759.7
NC_004842:950058:9562099562099586382430Anaplasma marginale str. St. Maries, complete genomeVirB4 protein1e-0759.7
NC_007950:206474:2165752165752191272553Polaromonas sp. JS666 plasmid 2, complete sequenceType IV secretory pathway VirB4 components-like4e-0757.4
NC_013192:1033177:1054164105416410566472484Leptotrichia buccalis DSM 1135, complete genomeCagE TrbE VirB component of type IV transporter system8e-0756.6
NC_015844:3580591:3589954358995435922932340Zobellia galactanivorans, complete genomeconjugative transposon protein TraG2e-0655.5