Pre_GI: BLASTP Hits

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Query: NC_017376:57500:90246 Helicobacter pylori SNT49 chromosome, complete genome

Start: 90246, End: 91787, Length: 1542

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017358:220900:2366782366782382191542Helicobacter pylori Cuz20 chromosome, complete genomeconjugal plasmid transfer system protein0994
NC_017367:278916:2931542931542946951542Helicobacter pylori F57, complete genomeComponent of conjugal plasmid transfer system0992
NC_010698:870312:9034759034759050161542Helicobacter pylori Shi470, complete genomeComponent of conjugal plasmid transfer system0989
NC_011498:448000:4822524822524837841533Helicobacter pylori P12, complete genomeVirB9 type IV secretion protein0988
NC_011333:1040192:1054550105455010560911542Helicobacter pylori G27 chromosome, complete genomecomB9-like competence protein0987
NC_017379:1035464:1049618104961810511351518Helicobacter pylori Puno135 chromosome, complete genomeconjugal plasmid transfer system protein0961
NC_017361:930280:9633939633939649341542Helicobacter pylori SouthAfrica7 chromosome, complete genomecomB9-like competence protein0956
NC_014555:1526775:1546070154607015475871518Helicobacter pylori PeCan4 chromosome, complete genomeVirB9 type IV secretion protein0951
NC_017361:1528239:1538332153833215398641533Helicobacter pylori SouthAfrica7 chromosome, complete genomeVirB9 type IV secretion protein0938
NC_017371:1030148:1038062103806210392791218Helicobacter pylori Gambia94/24 chromosome, complete genomeconjugal plasmid transfer system protein0735
NC_014256:448710:461230461230462117888Helicobacter pylori B8 chromosome, complete genomecomponent of conjugal plasmid transfer system5e-154544
NC_017381:982216:991578991578992324747Helicobacter pylori 2018 chromosome, complete genomeConjugal plasmid transfer system protein7e-116417
NC_017374:974279:983623983623984369747Helicobacter pylori 2017 chromosome, complete genomeconjugal plasmid transfer system protein7e-116417
NC_017357:973392:982736982736983482747Helicobacter pylori 908 chromosome, complete genomehypothetical protein7e-116417
NC_017357:973392:983476983476984003528Helicobacter pylori 908 chromosome, complete genomeconjugal plasmid transfer system protein5e-87322
NC_017374:974279:984363984363984890528Helicobacter pylori 2017 chromosome, complete genomeconjugal plasmid transfer system protein5e-87322
NC_017381:982216:992318992318992845528Helicobacter pylori 2018 chromosome, complete genomeConjugal plasmid transfer system protein5e-87322
NC_014256:448710:462243462243462746504Helicobacter pylori B8 chromosome, complete genomehypothetical protein3e-87322
NC_017372:748097:7903117903117919061596Helicobacter pylori India7 chromosome, complete genometype IV secretion system protein VirB97e-59228
NC_005090:1033746:105169710516971052626930Wolinella succinogenes DSM 1740, complete genomeCOMB23e-51203
NC_014256:485969:5191195191195207741656Helicobacter pylori B8 chromosome, complete genometype IV secretion system protein VirB94e-36152
NC_017371:1470582:1513397151339715150521656Helicobacter pylori Gambia94/24 chromosome, complete genometype IV secretion system protein VirB94e-36152
NC_017063:834674:8441078441078455611455Helicobacter pylori ELS37 chromosome, complete genometype IV secretion system protein VirB97e-36152
NC_011498:1391788:1400969140096914026241656Helicobacter pylori P12, complete genomeVirB9 type IV secretion protein3e-35150
NC_017375:77142:991989919899674477Helicobacter pylori 83 chromosome, complete genomecompetence factor transporter ComB4e-35149
NC_017375:77142:9977099770100213444Helicobacter pylori 83 chromosome, complete genomehypothetical protein4e-0963.2
NC_007799:186000:206250206250207062813Ehrlichia chaffeensis str. Arkansas, complete genometype IV secretion system protein, VirB94e-0756.6
NC_007354:1087456:110492211049221105734813Ehrlichia canis str. Jake, complete genomeConjugal transfer protein TrbG/VirB9/CagX4e-0653.1
NC_012026:75812:771727717277984813Anaplasma marginale str. Florida, complete genomeconjugal transfer protein trbG precursor (trbG)9e-0652
NC_004842:62000:777757777578587813Anaplasma marginale str. St. Maries, complete genomeconjugal transfer protein trbG precursor1e-0552