Pre_GI: BLASTP Hits

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Query: NC_017376:57500:70062 Helicobacter pylori SNT49 chromosome, complete genome

Start: 70062, End: 78488, Length: 8427

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017375:1498000:1504994150499415134118418Helicobacter pylori 83 chromosome, complete genomeDNA methylase05101
NC_011498:448000:4620964620964705228427Helicobacter pylori P12, complete genomeDNA methylase05058
NC_011333:1040192:1067764106776410761908427Helicobacter pylori G27 chromosome, complete genomeadenine specific DNA methyltransferase05057
NC_010698:870312:8833758833758917868412Helicobacter pylori Shi470, complete genomehypothetical protein05054
NC_017367:278916:3063993063993148558457Helicobacter pylori F57, complete genomehypothetical protein05012
NC_017362:1512959:1542212154221215508128601Helicobacter pylori Lithuania75 chromosome, complete genomeadenine specific DNA methyltransferase04989
NC_017372:748097:7732547732547818548601Helicobacter pylori India7 chromosome, complete genomeadenine specific DNA methyltransferase04969
NC_017361:1528239:1550176155017615585848409Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein04962
NC_017361:930280:9432999432999517078409Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein04947
NC_017063:834674:8539908539908625368547Helicobacter pylori ELS37 chromosome, complete genomeadenine specific DNA methyltransferase04922
NC_014560:1366747:1382017138201713905218505Helicobacter pylori SJM180 chromosome, complete genomeadenine specific DNA methyltransferase04907
NC_017378:1518529:1526278152627815321095832Helicobacter pylori Puno120 chromosome, complete genomehypothetical protein03594
NC_000921:1007519:1025324102532410320196696Helicobacter pylori J99, complete genomehypothetical protein03439
NC_014256:448710:4717384717384792947557Helicobacter pylori B8 chromosome, complete genomehypothetical protein02978
NC_017366:1055319:1062619106261910661703552Helicobacter pylori F32, complete genomehypothetical protein02152
NC_014801:1:2447244782545808Campylobacter jejuni subsp. jejuni ICDCCJ07001 plasmid pTet,cpp1401076
NC_009714:113975:1366831366831430366354Campylobacter hominis ATCC BAA-381, complete genomeCpp140797
NC_000921:1007519:1023777102377710251741398Helicobacter pylori J99, complete genomehypothetical protein0650
NC_018867:10238:3975439754464676714Dehalobacter sp. CF chromosome, complete genomeDNA methylase2e-160568
NC_016048:2873669:2873669287366928818468178Oscillibacter valericigenes Sjm18-20, complete genomeputative helicase3e-148528
NC_014828:2038692:2038692203869220460807389Ethanoligenens harbinense YUAN-3 chromosome, complete genomeDEAD-like helicase2e-147525
NC_008023:1070986:1103910110391011111607251Streptococcus pyogenes MGAS2096, complete genomeSuperfamily II DNA and RNA helicase5e-138494
NC_018866:63498:8623786237938087572Dehalobacter sp. DCA chromosome, complete genomeSuperfamily II DNA and RNA helicase4e-113411
NC_012781:3315614:3326686332668633343687683Eubacterium rectale ATCC 33656, complete genomepossible adenine-specific DNA methylase3e-113411
NC_012470:1390285:1417879141787914266298751Streptococcus equi subsp. zooepidemicus, complete genomehelicase6e-112407
NC_004116:1276791:1283738128373812905626825Streptococcus agalactiae 2603V/R, complete genomeSNF2 family protein3e-111405
NC_004668:2198027:2223189222318922327109522Enterococcus faecalis V583, complete genomehypothetical protein3e-111405
NC_014393:2771774:2771774277177427805028729Clostridium cellulovorans 743B chromosome, complete genome4e-109398
NC_013316:2033906:2098383209838321071128730Clostridium difficile R20291, complete genomeputative helicase9e-109397
NC_016630:1247251:1274510127451012833448835Filifactor alocis ATCC 35896 chromosome, complete genomesuperfamily II DNA and RNA helicase5e-109397
NC_013192:1033177:1035019103501910414146396Leptotrichia buccalis DSM 1135, complete genomehelicase domain protein3e-107391
NC_018867:121512:1272861272861351547869Dehalobacter sp. CF chromosome, complete genomehypothetical protein5e-106387
NC_012471:1197534:12378191237819124974611928Streptococcus equi subsp. equi 4047, complete genomeconjugative transposon DNA recombination protein9e-106387
NC_009089:478328:4961224961225048458724Clostridium difficile 630, complete genomeputative helicase1e-105386
NC_009089:2150062:2155769215576921648049036Clostridium difficile 630, complete genomeputative conjugative transposon DNA recombination protein3e-105385
NC_013164:67500:8255982559888556297Anaerococcus prevotii DSM 20548 plasmid pAPRE01, complete sequencehelicase domain protein7e-105384
NC_012654:237175:2477992477992517193921Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequencesuperfamily II DNA and RNA helicase2e-104382
NC_015977:3424178:3490227349022734964846258Roseburia hominis A2-183 chromosome, complete genomehelicase4e-103378
NC_015600:1161640:1169203116920311751995997Streptococcus pasteurianus ATCC 43144, complete genomeSNF2/helicase family protein1e-102376
NC_014624:1768226:1789525178952517970187494Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein2e-101372
NC_015422:3413386:3448201344820134532435043Alicycliphilus denitrificans K601 chromosome, complete genomeDEAD-like helicase2e-101372
NC_013211:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-020, completeDNA methylase/helicase SNF27e-94347
NC_017105:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-01-42C plasmid pAPA42C_020,DNA methylase/helicase SNF27e-94347
NC_017113:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-020, completeDNA methylase/helicase SNF27e-94347
NC_017118:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-020, completeDNA methylase/helicase SNF27e-94347
NC_017122:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-07 plasmid pAPA07-020, completeDNA methylase/helicase SNF27e-94347
NC_017126:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-22 plasmid pAPA22-020, completeDNA methylase/helicase SNF27e-94347
NC_017131:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-020, completeDNA methylase/helicase SNF27e-94347
NC_017149:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-020, completeDNA methylase/helicase SNF27e-94347
NC_011881:46654:4665446654514744821Arthrobacter chlorophenolicus A6 plasmid pACHL02, completehelicase domain protein3e-89332
NC_008757:206036:2060362060362109854950Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, completehelicase, C-terminal5e-88328
NC_008539:1:101047374728Arthrobacter sp. FB24 plasmid 3, complete sequencehelicase domain protein3e-88328
NC_014041:3715000:3721081372108137266095529Zunongwangia profunda SM-A87 chromosome, complete genomeputative DNA methylase5e-81304
NC_015311:2531616:2533794253379425400756282Prevotella denticola F0289 chromosome, complete genomehelicase C-terminal domain-containing protein5e-80301
NC_016749:1371997:1375578137557813823996822Streptococcus macedonicus ACA-DC 198, complete genomeSNF2 family protein2e-79299
NC_015571:1030527:1030527103052710360195493Porphyromonas gingivalis TDC60, complete genomeDNA methylase1e-76290
NC_016776:215500:2197882197882252745487Bacteroides fragilis 638R, complete genomeputative DNA methylase4e-76288
NC_015177:1859879:1863608186360818690465439Pedobacter saltans DSM 12145 chromosome, complete genomeN-6 DNA methylase9e-74280
NC_015052:1313311:1342134134213413485806447Bifidobacterium longum subsp. infantis 157F, complete genomehypothetical protein8e-73277
NC_015164:438000:4633524633524683254974Bacteroides salanitronis DSM 18170 chromosome, complete genomehelicase domain-containing protein4e-72275
NC_010729:1179008:1196323119632311997903468Porphyromonas gingivalis ATCC 33277, complete genomeputative DNA methylase2e-71272
NC_016776:2411154:2416657241665724223925736Bacteroides fragilis 638R, complete genomeputative DNA methylase1e-70270
NC_004663:2859158:2903302290330229090285727Bacteroides thetaiotaomicron VPI-5482, complete genomeputative DNA methylase8e-70267
NC_015571:2044000:2044072204407220474853414Porphyromonas gingivalis TDC60, complete genomeDNA methylase8e-70267
NC_015164:2935363:2947762294776229535935832Bacteroides salanitronis DSM 18170 chromosome, complete genomehelicase domain-containing protein2e-68263
NC_016610:1310275:1323084132308413289485865Tannerella forsythia ATCC 43037 chromosome, complete genomehelicase C-terminal domain-containing protein3e-68262
NC_019744:20500:2169421694268115118Cylindrospermum stagnale PCC 7417 plasmid pCYLST.02, completeDNA methylase1e-67260
NC_014371:849198:8669838669838715964614Prevotella melaninogenica ATCC 25845 chromosome chromosome II,hypothetical protein5e-67258
NC_004663:6223442:6231192623119262351543963Bacteroides thetaiotaomicron VPI-5482, complete genomeputative DNA methylase4e-67258
NC_006347:143876:1500911500911559075817Bacteroides fragilis YCH46, complete genomeputative DNA methylase1e-66256
NC_009614:2723262:2728033272803327319953963Bacteroides vulgatus ATCC 8482 chromosome, complete genomeDNA methylase2e-66256
NC_015311:1860666:1875988187598818804634476Prevotella denticola F0289 chromosome, complete genomehypothetical protein1e-64250
NC_018866:63498:6349863498695276030Dehalobacter sp. DCA chromosome, complete genomeSuperfamily II DNA and RNA helicase3e-64249
NC_012470:1390285:1402182140218214043142133Streptococcus equi subsp. zooepidemicus, complete genome5e-42175
NC_000921:1007519:103202510320251032477453Helicobacter pylori J99, complete genomehypothetical protein2e-41172
NC_014828:1019533:1042524104252410437381215Ethanoligenens harbinense YUAN-3 chromosome, complete genomehypothetical protein8e-36154
NC_002950:1571383:1576239157623915785302292Porphyromonas gingivalis W83, complete genomehypothetical protein6e-30135
NC_015311:1860666:1898091189809118995661476Prevotella denticola F0289 chromosome, complete genomehelicase C-terminal domain-containing protein3e-28129
NC_018939:1044000:106220310622031062439237Helicobacter pylori 26695 chromosome, complete genomeadenine specific DNA methyltransferase4e-28129
NC_002950:879930:9078949078949094741581Porphyromonas gingivalis W83, complete genomehypothetical protein7e-28128
NC_012471:719000:748826748826749062237Streptococcus equi subsp. equi 4047, complete genome5e-20102
NC_000915:1044000:106223610622361062421186Helicobacter pylori 26695, complete genomehypothetical protein5e-1999
NC_015385:1838268:1857415185741518661208706Treponema succinifaciens DSM 2489 chromosome, complete genomeSNF2-related protein3e-1896.3
NC_015386:150000:1544931544931609006408Treponema succinifaciens DSM 2489 plasmid pTRESU01, completeSNF2-related protein4e-1895.9
NC_015571:2044000:2047485204748520497642280Porphyromonas gingivalis TDC60, complete genomeN-6 DNA Methylase3e-1483.2
NC_017177:192933:194771194771195619849Clostridium difficile BI1, complete genomeN-6 DNA methylase1e-1277.8
NC_008255:1701195:170564117056411706405765Cytophaga hutchinsonii ATCC 33406, complete genomepossible adenine-specific DNA methylase1e-1071.2
NC_012654:237175:244155244155245033879Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequencesuperfamily II DNA and RNA helicase2e-0863.9
NC_013716:3512950:3527236352723635287381503Citrobacter rodentium ICC168, complete genomeputative type I restriction modification system HsdM component5e-0758.9
NC_008023:1070986:109209210920921093030939Streptococcus pyogenes MGAS2096, complete genomeSuperfamily II DNA and RNA helicase2e-0657
NC_014306:4376012:4401437440143744029091473Erwinia billingiae Eb661, complete genomeType I restriction enzyme EcoEI M protein2e-0656.6
NC_019968:1084288:1111083111108311121651083Prevotella dentalis DSM 3688 chromosome 2, complete sequence3e-0656.6