Pre_GI: BLASTP Hits

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Query: NC_017375:1498000:1520887 Helicobacter pylori 83 chromosome, complete genome

Start: 1520887, End: 1521963, Length: 1077

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017358:220900:2651522651522662281077Helicobacter pylori Cuz20 chromosome, complete genomeintegrase/recombinase (xerD)0690
NC_010698:870312:8749988749988760741077Helicobacter pylori Shi470, complete genomeintegrase/recombinase (xerD)0687
NC_017361:930280:9347909347909358661077Helicobacter pylori SouthAfrica7 chromosome, complete genomeintegrase-recombinase protein0680
NC_017362:1512959:1520655152065515217221068Helicobacter pylori Lithuania75 chromosome, complete genomeintegrase/recombinase (xerD)2e-108392
NC_014560:1366747:1408465140846514095321068Helicobacter pylori SJM180 chromosome, complete genomeintegrase/recombinase (xerD)8e-108390
NC_014256:485969:4933274933274943941068Helicobacter pylori B8 chromosome, complete genomehypothetical protein1e-107390
NC_017063:834674:8796738796738807401068Helicobacter pylori ELS37 chromosome, complete genomeintegrase/recombinase (xerD)2e-107389
NC_014555:1526775:1534128153412815351951068Helicobacter pylori PeCan4 chromosome, complete genomeintegrase/recombinase (xerD)1e-107389
NC_017372:748097:7561247561247571911068Helicobacter pylori India7 chromosome, complete genomeintegrase/recombinase (xerD)3e-107388
NC_018939:1044000:1056175105617510572421068Helicobacter pylori 26695 chromosome, complete genomeintegrase/recombinase (xerD)3e-107388
NC_000915:1044000:1056158105615810572251068Helicobacter pylori 26695, complete genomeintegrase/recombinase (xerD)3e-107388
NC_017371:1470582:1477848147784814789181071Helicobacter pylori Gambia94/24 chromosome, complete genomeintegrase/recombinase (xerD)8e-107387
NC_011498:448000:4524234524234534961074Helicobacter pylori P12, complete genomeintegrase/recombinase XercD family6e-100364
NC_000921:1007519:1055965105596510570381074Helicobacter pylori J99, complete genomeINTEGRASE/RECOMBINASE (XERCD FAMILY)6e-100364
NC_014256:485969:5275845275845286571074Helicobacter pylori B8 chromosome, complete genomeXerCD family integrase/recombinase2e-99362
NC_017375:77142:791237912380088966Helicobacter pylori 83 chromosome, complete genomeintegrase/recombinase9e-94343
NC_014560:1366747:137234113723411373312972Helicobacter pylori SJM180 chromosome, complete genomeintegrase/recombinase XercD family protein8e-88323
NC_000921:1007519:104368410436841044679996Helicobacter pylori J99, complete genomeINTEGRASE/RECOMBINASE (XERCD FAMILY)1e-76286
NC_017376:57500:622216222162580360Helicobacter pylori SNT49 chromosome, complete genomeintegrase-recombinase protein8e-62237
NC_015674:1605923:160943716094371610171735Helicobacter bizzozeronii CIII-1, complete genomeintegrase/recombinase XerD2e-60233
NC_017381:982216:9995029995021000038537Helicobacter pylori 2018 chromosome, complete genomeintegrase/recombinase9e-50197
NC_017374:974279:991547991547992083537Helicobacter pylori 2017 chromosome, complete genomeXERCD family protein/integrase/ recombinase9e-50197
NC_017357:973392:990660990660991196537Helicobacter pylori 908 chromosome, complete genomehypothetical protein9e-50197
NC_017357:973392:991163991163991750588Helicobacter pylori 908 chromosome, complete genomeintegrase/recombinase1e-43177
NC_017374:974279:992050992050992637588Helicobacter pylori 2017 chromosome, complete genomeXERCD family protein/integrase/ recombinase1e-43177
NC_017381:982216:100000510000051000592588Helicobacter pylori 2018 chromosome, complete genomeintegrase/recombinase1e-43177
NC_015674:1605923:160891616089161609266351Helicobacter bizzozeronii CIII-1, complete genomeXerCD family integrase/recombinase1e-35150
NC_018012:4054000:405605640560564056955900Thiocystis violascens DSM 198 chromosome, complete genometyrosine recombinase XerD2e-1170.9
NC_010371:57683:7555775557766361080Finegoldia magna ATCC 29328 plasmid pFMC, complete sequenceputative integrase2e-1170.1
NC_020291:4357425:436516743651674366105939Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genometyrosine recombinase XerC4e-1065.9
NC_010338:2136193:215343121534312154423993Caulobacter sp. K31, complete genomeintegrase family protein2e-0963.9
NC_010278:1989500:1989861198986119908711011Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,site-specific tyrosine recombinase XerC1e-0861.2
NC_016612:477407:507534507534508430897Klebsiella oxytoca KCTC 1686 chromosome, complete genomesite-specific tyrosine recombinase XerD1e-0860.8
NC_009053:2025782:2028258202825820292681011Actinobacillus pleuropneumoniae L20, complete genomeTyrosine recombinase xerC1e-0860.8
NC_010939:2085000:208550420855042086424921Actinobacillus pleuropneumoniae serovar 7 str. AP76, completeTyrosine recombinase xerC2e-0860.5
NC_006361:1665378:170699417069941707866873Nocardia farcinica IFM 10152, complete genomeputative phage integrase2e-0860.1
NC_020064:3825916:384373738437373844636900Serratia marcescens FGI94, complete genometyrosine recombinase XerD5e-0858.9
NC_012781:2552723:255584125558412556761921Eubacterium rectale ATCC 33656, complete genomeintegrase/recombinase-like protein1e-0758.2
NC_021184:4456904:446240944624094463341933Desulfotomaculum gibsoniae DSM 7213, complete genomesite-specific recombinase XerD8e-0858.2
NC_016510:2312481:2327858232785823288921035Flavobacterium columnare ATCC 49512 chromosome, complete genometyrosine recombinase XerD1e-0757.4
NC_005877:864118:866941866941867771831Picrophilus torridus DSM 9790, complete genomeDNA integration/recombination/invertion protein2e-0757
NC_012962:1068102:1084715108471510861331419Photorhabdus asymbiotica, complete genomeputative integrase/recombinase3e-0756.6
NC_012962:3463644:3471785347178534732031419Photorhabdus asymbiotica, complete genomeputative integrase3e-0756.6
NC_012962:1068102:1092488109248810939061419Photorhabdus asymbiotica, complete genomeputative integrase/recombinase3e-0756.6
NC_016048:308342:325057325057325737681Oscillibacter valericigenes Sjm18-20, complete genomeputative site-specific recombinase4e-0756.2
NC_013199:1407742:142829114282911429190900Lactobacillus rhamnosus Lc 705, complete genometyrosine recombinase XerC subunit6e-0755.5
NC_016048:2055199:2072316207231620733231008Oscillibacter valericigenes Sjm18-20, complete genometyrosine recombinase XerC5e-0755.5
NC_009922:1917271:192236419223641923302939Alkaliphilus oremlandii OhILAs, complete genomeintegrase family protein7e-0755.1
NC_021184:4456904:446146844614684462346879Desulfotomaculum gibsoniae DSM 7213, complete genomesite-specific recombinase XerD1e-0654.7
NC_014933:220146:2444792444792456091131Bacteroides helcogenes P 36-108 chromosome, complete genomeintegrase family protein1e-0654.3
NC_009253:829913:844973844973845854882Desulfotomaculum reducens MI-1 chromosome, complete genomephage integrase family protein1e-0654.3
NC_003228:2010643:203162020316202032504885Bacteroides fragilis NCTC 9343, complete genomeputative tyrosine recombinase1e-0654.3
NC_019960:1658657:168363516836351684561927Prevotella dentalis DSM 3688 chromosome 1, complete sequencesite-specific recombinase XerD1e-0654.3
NC_014644:1:9188918810021834Gardnerella vaginalis ATCC 14019 chromosome, complete genomephage integrase1e-0654.3
NC_009712:669647:689909689909690829921Candidatus Methanoregula boonei 6A8, complete genomephage integrase family protein2e-0653.5
NC_018645:3029785:304225930422593043233975Desulfobacula toluolica Tol2, complete genometyrosine recombinase subunit C XerC32e-0653.5
NC_012416:753500:784436784436785356921Wolbachia sp. wRi, complete genomesite-specific recombinase, phage integrase family4e-0652.8
NC_010163:1193237:121498912149891215909921Acholeplasma laidlawii PG-8A chromosome, complete genomeintegrase/recombinase, XerD-like protein6e-0652
NC_014377:1060000:106688810668881067784897Thermosediminibacter oceani DSM 16646 chromosome, complete genometyrosine recombinase XerC8e-0651.6
NC_016001:905164:911276911276912172897Flavobacterium branchiophilum, complete genomeTyrosine recombinase XerC8e-0651.6