Pre_GI: BLASTP Hits

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Query: NC_017375:1498000:1504994 Helicobacter pylori 83 chromosome, complete genome

Start: 1504994, End: 1513411, Length: 8418

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014393:2771774:2771774277177427805028729Clostridium cellulovorans 743B chromosome, complete genome2e-104382
NC_012470:1390285:1402182140218214043142133Streptococcus equi subsp. zooepidemicus, complete genome8e-43177
NC_019968:1084288:1111083111108311121651083Prevotella dentalis DSM 3688 chromosome 2, complete sequence4e-0656.2
NC_012471:719000:748826748826749062237Streptococcus equi subsp. equi 4047, complete genome3e-20102
NC_017362:1512959:1542212154221215508128601Helicobacter pylori Lithuania75 chromosome, complete genomeadenine specific DNA methyltransferase04987
NC_017063:834674:8539908539908625368547Helicobacter pylori ELS37 chromosome, complete genomeadenine specific DNA methyltransferase04922
NC_014560:1366747:1382017138201713905218505Helicobacter pylori SJM180 chromosome, complete genomeadenine specific DNA methyltransferase04926
NC_018939:1044000:106220310622031062439237Helicobacter pylori 26695 chromosome, complete genomeadenine specific DNA methyltransferase1e-29134
NC_011333:1040192:1067764106776410761908427Helicobacter pylori G27 chromosome, complete genomeadenine specific DNA methyltransferase05074
NC_017372:748097:7732547732547818548601Helicobacter pylori India7 chromosome, complete genomeadenine specific DNA methyltransferase04943
NC_012471:1197534:12378191237819124974611928Streptococcus equi subsp. equi 4047, complete genomeconjugative transposon DNA recombination protein1e-102376
NC_014801:1:2447244782545808Campylobacter jejuni subsp. jejuni ICDCCJ07001 plasmid pTet,cpp1401047
NC_009714:113975:1366831366831430366354Campylobacter hominis ATCC BAA-381, complete genomeCpp140786
NC_015422:3413386:3448201344820134532435043Alicycliphilus denitrificans K601 chromosome, complete genomeDEAD-like helicase3e-99365
NC_014828:2038692:2038692203869220460807389Ethanoligenens harbinense YUAN-3 chromosome, complete genomeDEAD-like helicase9e-139496
NC_011498:448000:4620964620964705228427Helicobacter pylori P12, complete genomeDNA methylase05078
NC_019744:20500:2169421694268115118Cylindrospermum stagnale PCC 7417 plasmid pCYLST.02, completeDNA methylase5e-66255
NC_017376:57500:7006270062784888427Helicobacter pylori SNT49 chromosome, complete genomeDNA methylase05129
NC_018867:10238:3975439754464676714Dehalobacter sp. CF chromosome, complete genomeDNA methylase3e-157558
NC_015571:2044000:2044072204407220474853414Porphyromonas gingivalis TDC60, complete genomeDNA methylase4e-66255
NC_009614:2723262:2728033272803327319953963Bacteroides vulgatus ATCC 8482 chromosome, complete genomeDNA methylase1e-64250
NC_015571:1030527:1030527103052710360195493Porphyromonas gingivalis TDC60, complete genomeDNA methylase7e-76287
NC_017126:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-22 plasmid pAPA22-020, completeDNA methylase/helicase SNF29e-92340
NC_017105:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-01-42C plasmid pAPA42C_020,DNA methylase/helicase SNF29e-92340
NC_017131:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-020, completeDNA methylase/helicase SNF29e-92340
NC_017113:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-020, completeDNA methylase/helicase SNF29e-92340
NC_017149:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-020, completeDNA methylase/helicase SNF29e-92340
NC_017118:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-020, completeDNA methylase/helicase SNF29e-92340
NC_017122:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-07 plasmid pAPA07-020, completeDNA methylase/helicase SNF29e-92340
NC_013211:163390:1633901633901685165127Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-020, completeDNA methylase/helicase SNF29e-92340
NC_012470:1390285:1417879141787914266298751Streptococcus equi subsp. zooepidemicus, complete genomehelicase1e-108396
NC_015977:3424178:3490227349022734964846258Roseburia hominis A2-183 chromosome, complete genomehelicase2e-97358
NC_015311:2531616:2533794253379425400756282Prevotella denticola F0289 chromosome, complete genomehelicase C-terminal domain-containing protein2e-77292
NC_015311:1860666:1898091189809118995661476Prevotella denticola F0289 chromosome, complete genomehelicase C-terminal domain-containing protein3e-28129
NC_016610:1310275:1323084132308413289485865Tannerella forsythia ATCC 43037 chromosome, complete genomehelicase C-terminal domain-containing protein9e-68260
NC_013164:67500:8255982559888556297Anaerococcus prevotii DSM 20548 plasmid pAPRE01, complete sequencehelicase domain protein1e-101373
NC_011881:46654:4665446654514744821Arthrobacter chlorophenolicus A6 plasmid pACHL02, completehelicase domain protein4e-86322
NC_013192:1033177:1035019103501910414146396Leptotrichia buccalis DSM 1135, complete genomehelicase domain protein6e-101370
NC_008539:1:101047374728Arthrobacter sp. FB24 plasmid 3, complete sequencehelicase domain protein2e-86322
NC_015164:2935363:2947762294776229535935832Bacteroides salanitronis DSM 18170 chromosome, complete genomehelicase domain-containing protein4e-68261
NC_015164:438000:4633524633524683254974Bacteroides salanitronis DSM 18170 chromosome, complete genomehelicase domain-containing protein4e-74281
NC_008757:206036:2060362060362109854950Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, completehelicase, C-terminal3e-85318
NC_000921:1007519:1025324102532410320196696Helicobacter pylori J99, complete genomehypothetical protein03994
NC_014828:1019533:1042524104252410437381215Ethanoligenens harbinense YUAN-3 chromosome, complete genomehypothetical protein4e-36155
NC_002950:879930:9078949078949094741581Porphyromonas gingivalis W83, complete genomehypothetical protein3e-28129
NC_017361:930280:9432999432999517078409Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein04997
NC_017366:1055319:1062619106261910661703552Helicobacter pylori F32, complete genomehypothetical protein02159
NC_014371:849198:8669838669838715964614Prevotella melaninogenica ATCC 25845 chromosome chromosome II,hypothetical protein3e-64249
NC_000921:1007519:103202510320251032477453Helicobacter pylori J99, complete genomehypothetical protein2e-39166
NC_017367:278916:3063993063993148558457Helicobacter pylori F57, complete genomehypothetical protein05131
NC_017361:1528239:1550176155017615585848409Helicobacter pylori SouthAfrica7 chromosome, complete genomehypothetical protein05014
NC_014256:448710:4717384717384792947557Helicobacter pylori B8 chromosome, complete genomehypothetical protein02966
NC_000921:1007519:1023777102377710251741398Helicobacter pylori J99, complete genomehypothetical protein0674
NC_018867:121512:1272861272861351547869Dehalobacter sp. CF chromosome, complete genomehypothetical protein6e-103377
NC_015052:1313311:1342134134213413485806447Bifidobacterium longum subsp. infantis 157F, complete genomehypothetical protein6e-70268
NC_000915:1044000:106223610622361062421186Helicobacter pylori 26695, complete genomehypothetical protein3e-20102
NC_010698:870312:8833758833758917868412Helicobacter pylori Shi470, complete genomehypothetical protein05184
NC_017378:1518529:1526278152627815321095832Helicobacter pylori Puno120 chromosome, complete genomehypothetical protein03607
NC_004668:2198027:2223189222318922327109522Enterococcus faecalis V583, complete genomehypothetical protein2e-105385
NC_014624:1768226:1789525178952517970187494Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein4e-101371
NC_015311:1860666:1875988187598818804634476Prevotella denticola F0289 chromosome, complete genomehypothetical protein3e-60235
NC_002950:1571383:1576239157623915785302292Porphyromonas gingivalis W83, complete genomehypothetical protein2e-31140
NC_015177:1859879:1863608186360818690465439Pedobacter saltans DSM 12145 chromosome, complete genomeN-6 DNA methylase4e-75285
NC_017177:192933:194771194771195619849Clostridium difficile BI1, complete genomeN-6 DNA methylase3e-1379.7
NC_015571:2044000:2047485204748520497642280Porphyromonas gingivalis TDC60, complete genomeN-6 DNA Methylase7e-1688.6
NC_008255:1701195:170564117056411706405765Cytophaga hutchinsonii ATCC 33406, complete genomepossible adenine-specific DNA methylase3e-1173.2
NC_012781:3315614:3326686332668633343687683Eubacterium rectale ATCC 33656, complete genomepossible adenine-specific DNA methylase1e-108396
NC_009089:2150062:2155769215576921648049036Clostridium difficile 630, complete genomeputative conjugative transposon DNA recombination protein1e-103379
NC_016776:215500:2197882197882252745487Bacteroides fragilis 638R, complete genomeputative DNA methylase2e-76289
NC_004663:2859158:2903302290330229090285727Bacteroides thetaiotaomicron VPI-5482, complete genomeputative DNA methylase5e-70268
NC_010729:1179008:1196323119632311997903468Porphyromonas gingivalis ATCC 33277, complete genomeputative DNA methylase4e-69265
NC_014041:3715000:3721081372108137266095529Zunongwangia profunda SM-A87 chromosome, complete genomeputative DNA methylase4e-80301
NC_006347:143876:1500911500911559075817Bacteroides fragilis YCH46, complete genomeputative DNA methylase6e-67258
NC_016776:2411154:2416657241665724223925736Bacteroides fragilis 638R, complete genomeputative DNA methylase5e-70268
NC_004663:6223442:6231192623119262351543963Bacteroides thetaiotaomicron VPI-5482, complete genomeputative DNA methylase5e-65251
NC_016048:2873669:2873669287366928818468178Oscillibacter valericigenes Sjm18-20, complete genomeputative helicase7e-143510
NC_009089:478328:4961224961225048458724Clostridium difficile 630, complete genomeputative helicase7e-104380
NC_013316:2033906:2098383209838321071128730Clostridium difficile R20291, complete genomeputative helicase2e-107392
NC_007681:542494:5628195628195643451527Methanosphaera stadtmanae DSM 3091, complete genomeputative type I restriction-modification system, methyltransferase subunit4e-0656.2
NC_004116:1276791:1283738128373812905626825Streptococcus agalactiae 2603V/R, complete genomeSNF2 family protein2e-112409
NC_016749:1371997:1375578137557813823996822Streptococcus macedonicus ACA-DC 198, complete genomeSNF2 family protein3e-80302
NC_015386:150000:1544931544931609006408Treponema succinifaciens DSM 2489 plasmid pTRESU01, completeSNF2-related protein1e-1897.4
NC_015385:1838268:1857415185741518661208706Treponema succinifaciens DSM 2489 chromosome, complete genomeSNF2-related protein2e-19100
NC_015600:1161640:1169203116920311751995997Streptococcus pasteurianus ATCC 43144, complete genomeSNF2/helicase family protein3e-104381
NC_018866:63498:8623786237938087572Dehalobacter sp. DCA chromosome, complete genomeSuperfamily II DNA and RNA helicase5e-112407
NC_016630:1247251:1274510127451012833448835Filifactor alocis ATCC 35896 chromosome, complete genomesuperfamily II DNA and RNA helicase3e-107392
NC_012654:237175:2477992477992517193921Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequencesuperfamily II DNA and RNA helicase8e-99363
NC_018866:63498:6349863498695276030Dehalobacter sp. DCA chromosome, complete genomeSuperfamily II DNA and RNA helicase2e-62243
NC_012654:237175:244155244155245033879Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequencesuperfamily II DNA and RNA helicase1e-0761.2
NC_008023:1070986:1103910110391011111607251Streptococcus pyogenes MGAS2096, complete genomeSuperfamily II DNA and RNA helicase3e-114415
NC_008023:1070986:109209210920921093030939Streptococcus pyogenes MGAS2096, complete genomeSuperfamily II DNA and RNA helicase2e-0657