Pre_GI: BLASTP Hits

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Query: NC_017372:902043:911423 Helicobacter pylori India7 chromosome, complete genome

Start: 911423, End: 912883, Length: 1461

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014256:636000:6415956415956430551461Helicobacter pylori B8 chromosome, complete genomeintegral membrane protein MviN0705
NC_009715:905134:9296089296089310081401Campylobacter curvus 525.92 chromosome, complete genomeintegral membrane protein MviN2e-72273
NC_014315:3278386:3279917327991732814551539Nitrosococcus watsoni C-113 chromosome, complete genomeintegral membrane protein MviN3e-37156
NC_007484:3429140:3433639343363934351771539Nitrosococcus oceani ATCC 19707, complete genomeVirulence factor MVIN-like3e-34146
NC_012846:1679184:1696368169636816979391572Bartonella grahamii as4aup, complete genomevirulence factor MviN6e-32139
NC_004088:2491303:2503559250355925050941536Yersinia pestis KIM, complete genomevirulence factor2e-31137
NC_003143:2309500:2314426231442623159611536Yersinia pestis CO92, complete genomehypothetical protein2e-31137
NC_005810:2091930:2096856209685620983911536Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-31137
NC_010159:2546590:2558924255892425604591536Yersinia pestis Angola, complete genomeintegral membrane protein MviN2e-31137
NC_008149:1718000:1723042172304217245771536Yersinia pestis Nepal516, complete genomemembrane protein2e-31137
NC_006155:2378526:2383495238349523850301536Yersinia pseudotuberculosis IP 32953, complete genomevirulence factor mviN, possible MOP Superfamliy efflux pump3e-31137
NC_008150:1593500:1598714159871416002491536Yersinia pestis Antiqua, complete genomehypothetical protein2e-31137
NC_009381:1205900:1218072121807212196071536Yersinia pestis Pestoides F chromosome, complete genomemembrane protein2e-31137
NC_014029:2285323:2297547229754722990821536Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-31137
NC_009708:2347350:2358289235828923598241536Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeintegral membrane protein MviN2e-31137
NC_010634:2297000:2301404230140423029391536Yersinia pseudotuberculosis PB1/+, complete genomeintegral membrane protein MviN2e-31137
NC_017265:2213500:2225222222522222267571536Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative inner membrane protein2e-31137
NC_017168:3433804:3446012344601234475471536Yersinia pestis A1122 chromosome, complete genomevirulence factor MviN2e-31137
NC_017160:2212806:2225046222504622265811536Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-31137
NC_017154:2306421:2311347231134723128821536Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-31137
NC_010465:2383219:2395386239538623970141629Yersinia pseudotuberculosis YPIII, complete genomeintegral membrane protein MviN3e-31136
NC_018080:5192264:5212249521224952137871539Pseudomonas aeruginosa DK2 chromosome, complete genomevirulence factor, membrane protein4e-31136
NC_008463:5364428:5383305538330553848431539Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative virulence factor, membrane protein4e-31136
NC_008800:2592500:2602499260249926040341536Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein1e-30135
NC_007645:6049340:6071246607124660728141569Hahella chejuensis KCTC 2396, complete genomeintegral membrane protein MviN1e-30135
NC_010161:1811000:1826661182666118282321572Bartonella tribocorum CIP 105476, complete genomeMviN protein1e-30134
NC_020301:1449616:1467232146723214688031572Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomevirulence factor6e-30132
NC_009092:1263964:1264478126447812660371560Shewanella loihica PV-4, complete genomeintegral membrane protein MviN1e-29131
NC_013939:1417750:1437371143737114388521482Deferribacter desulfuricans SSM1, complete genomevirulence factor MviN1e-29131
NC_005955:1259393:1272665127266512742361572Bartonella quintana str. Toulouse, complete genomeVirulence factor mviN homolog3e-29130
NC_014532:349384:3661023661023677271626Halomonas elongata DSM 2581, complete genomeK03980 virulence factor5e-29129
NC_011420:2692857:2697251269725126987921542Rhodospirillum centenum SW, complete genomeintegral membrane protein MviN1e-28128
NC_011894:6001144:6016648601664860181771530Methylobacterium nodulans ORS 2060, complete genomeintegral membrane protein MviN2e-28127
NC_010995:3821327:3844192384419238457961605Cellvibrio japonicus Ueda107, complete genomeintegral membrane protein MviN2e-28127
NC_017059:967309:9800579800579816791623Rhodospirillum photometricum DSM 122, complete genomeVirulence factor MVIN-like4e-28126
NC_008322:3585601:3605321360532136068801560Shewanella sp. MR-7, complete genomeintegral membrane protein MviN8e-27122
NC_015424:3890293:3910355391035539118751521Aeromonas veronii B565 chromosome, complete genomeintegral membrane protein MviN3e-26120
NC_009052:1211989:1211989121198912135481560Shewanella baltica OS155, complete genomeintegral membrane protein MviN3e-26120
NC_016901:1367443:1367443136744313690021560Shewanella baltica OS678 chromosome, complete genomeintegral membrane protein MviN2e-26120
NC_015677:2939301:2964735296473529663001566Ramlibacter tataouinensis TTB310 chromosome, complete genomevirulence factor4e-26119
NC_006677:2042387:2057316205731620588721557Gluconobacter oxydans 621H, complete genomeVirulence factor MviN2e-25117
NC_010943:1332243:1368167136816713697861620Stenotrophomonas maltophilia K279a, complete genomeputative transmembrane virulence factor MmviN2e-24114
NC_009659:2849000:2851336285133628528861551Janthinobacterium sp. Marseille chromosome, complete genomevirulence factor MviN2e-23110
NC_008702:2378890:2396768239676823983061539Azoarcus sp. BH72, complete genomeprobable virulence factor3e-23110
NC_004344:129798:1510111510111525551545Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein2e-1687.8
NC_015633:2565753:2566760256676025683401581Vibrio anguillarum 775 chromosome chromosome I, complete sequenceMviN2e-1480.9
NC_010718:2492895:2506780250678025083241545Natranaerobius thermophilus JW/NM-WN-LF, complete genomeintegral membrane protein MviN5e-1376.3
NC_004347:3670145:3689664368966436912231560Shewanella oneidensis MR-1, complete genomeMviN protein4e-1273.6
NC_019757:4739206:4750188475018847515641377Cylindrospermum stagnale PCC 7417, complete genomeintegral membrane protein MviN2e-1171.2
NC_004842:1081271:1097053109705310984171365Anaplasma marginale str. St. Maries, complete genomevirulence factor MVIN4e-1169.7
NC_014774:239865:2575752575752591341560Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completeintegral membrane protein MviN7e-1168.9
NC_014831:786011:7860117860117876121602Thermaerobacter marianensis DSM 12885 chromosome, complete genomeintegral membrane protein MviN4e-1066.6
NC_014410:2511753:2519518251951825210741557Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,integral membrane protein MviN8e-1065.5
NC_009617:1165539:1181367118136711828931527Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeintegral membrane protein MviN9e-1065.5
NC_015577:862659:8798868798868814781593Treponema azotonutricium ZAS-9 chromosome, complete genomeintegral membrane protein MviN1e-0964.7
NC_012985:465354:4653544653544669101557Candidatus Liberibacter asiaticus str. psy62, complete genomeintegral membrane protein MviN2e-0964.3
NC_016148:1877711:1903176190317619046991524Thermovirga lienii DSM 17291 chromosome, complete genomeintegral membrane protein MviN5e-0962.8
NC_013222:2209340:2216535221653522178811347Robiginitalea biformata HTCC2501, complete genomeVirulence factor MVIN-like protein7e-0962.4
NC_008593:980731:9972499972499987961548Clostridium novyi NT, complete genomeintegral membrane protein MviN1e-0862
NC_009925:4864367:4868100486810048694851386Acaryochloris marina MBIC11017, complete genomevirulence factor MviN, putative2e-0861.2
NC_015714:542679:5538705538705554501581Treponema paraluiscuniculi Cuniculi A chromosome, complete genomeintegral membrane protein MviN9e-0858.5
NC_015573:2063925:2064976206497620665651590Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeintegral membrane protein MviN2e-0757.8
NC_000919:545141:5563275563275579071581Treponema pallidum subsp. pallidum str. Nichols, complete genomevirulence factor (mviN)2e-0757.4
NC_010741:546573:5577595577595593391581Treponema pallidum subsp. pallidum SS14, complete genomevirulence factor2e-0757.4
NC_016842:546661:5578475578475594271581Treponema pallidum subsp. pertenue str. SamoaD chromosome, completeintegral membrane protein MviN2e-0757.4
NC_016843:547149:5583355583355599151581Treponema pallidum subsp. pertenue str. Gauthier chromosome,integral membrane protein MviN2e-0757.4
NC_016844:547069:5582555582555598351581Treponema pallidum subsp. pallidum DAL-1 chromosome, completeintegral membrane protein MviN2e-0757.4
NC_016848:547115:5583015583015598811581Treponema pallidum subsp. pertenue str. CDC2 chromosome, completeintegral membrane protein MviN2e-0757.4
NC_017268:546376:5575625575625591421581Treponema pallidum subsp. pallidum str. Chicago chromosome,integral membrane protein MviN2e-0757.4
NC_021508:546592:5577785577785593581581Treponema pallidum subsp. pallidum SS14, complete genomeintegral membrane protein MviN2e-0757.4
NC_013525:766848:7668487668487683921545Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genomeintegral membrane protein MviN6e-0756.2
NC_015635:5154730:5202418520241852040191602Microlunatus phosphovorus NM-1, complete genomehypothetical protein1e-0654.7